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Author: xili.liu

[Challenge Topic] How to grow a yeast cell as large as a grape (Xili Liu)

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Posted at 2012-6-8 15:37:49 | All floors
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    Your idea seems to be the only method we can use , but it needs a lot of time.this problem is so difficult.   

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Posted at 2012-6-13 23:56:37 | All floors

I think the entry point of the question is why and how some species choose to be single-celled organism with large cell size (like Xenophyophores), against to be multicellular organism with relatively smaller cell size. The costs and benefits of the choice optimize certain species’ cell size in evolution to best adapt to the extracellular environment.
The study in yeast reminds me that cell stress response and the control of cell size and proliferation may be closely interrelated. For example in stress states the cell cycle stay temporally at G1 phase as well. And yeast cell is proved to frequently employ MAP kinase pathway in stress responses, while this pathway is also linked to signals of cell size and cell cycle control. So would it be possible that they are two sides of the coin in some sense to cope with the environment?

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Posted at 2012-6-16 22:17:44 | All floors
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    Maybe we can solve this problem by increasing copy numbers of the necessary genes. Also, poluploid cells are larger than haploid cells.
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