中文   |   BBS   |   Mail   |    会场预定
Contact

TEL:010-62759647

FAX:010-62759595

HOME > People > ying liuying liu

 

 

 Ying LIU


 

Liuying_at_pku.edu.cn

 

Associate Professor, College of Chemistry and Molecular Engineering, Peking UniversityMember of Center for Theoretical Biology, Peking University

 

 

Education:

 

B.Sc., 1984.7, Lanzhou University.
M.Sc., 1990.6, Lanzhou University. 
Ph.D., 1999.7, Nankai University.

 

 

Research interests:

 

Our research focus is on protein-ligand interaction. 
We base on three-dimensional structure of the proteins or biologic network to design, synthesize and bioassay the potential drugs. We synthesize novel organic molecules as probes to modulate the biosystem.

 



Academic  Work 
experiences:

 

Associate Professor, College of Chemistry and Molecular Engineering, Peking UniversityMember of Center for Theoretical Biology, Peking University.
Postdoctor,1999.7-2001.10, Peking University. 
Visiting Fellow, 2004.9-2005.2, Free University of Berlin, Germany.
DFG visiting Fellow, 2006.7-9, Free University of Berlin, Germany.

 


 

Selected publications:

 

1. Xiaolu Jiang, Lu Zhou, Dengguo Wei, Hu Meng, Ying Liu*, Luhua Lai*. Activation and inhibition of leukotriene A4 hydrolase aminopeptidase activity by diphenyl ether and derivatives. Bioorg. Med. Chem. Lett. 2008, 18(24), 6549-6552. 

2. Lu Zhou, Chao Fang, Ping Wei, Shiyong Liu, Ying Liu,* Luhua Lai.* Chemically Induced Dimerization of Human Nonpancreatic Secretory Phospholipase A2 by Bis-indole Derivatives. J. Med. Chem. 2008, 51(12), 3360 - 3366.

3. Yuxiu Liu, Dengguo Wei, Yerong Zhu, Shaohua Liu, Yonglin Zhang, Qiqi Zhao, Baoli Cai, Yonghong Li, Haibin Song, Ying Liu,* Yong Wang,* Runqiu Huang, Qingmin Wang.* Synthesis, Herbicidal Activities, and 3D-QSAR of 2-Cyanoacrylates Containing Aromatic Methylamine Moieties. J. Agric. Food Chem.2008, 56(1), 204–212.

4. Lu Zhou, Ying Liu,* Weilin Zhang, Ping Wei, Changkang Huang, Jianfeng Pei, Yaxia Yuan, Luhua Lai.* Isatin Compounds as Noncovalent SARS Coronavirus 3C-like Protease Inhibitors. J. Med. Chem. 2006, 49 (12), 3440 – 3443.

5. Zhengming Liu, Changkang Huang, Keqiang Fan, Ping Wei, Hao Chen, Sen Liu, Jianfeng Pei, Lei Shi, Bo Li, Kun Yang, Ying Liu,* Luhua Lai.* Virtual Screening of Novel Noncovalent Inhibitors for SARS-CoV 3C-like Proteinase. J. Chem. Inf. Model. 2005, 45(1), 10-17.

 

 

Other Activities:

1. Lu-hua Lai, Ying Liu, Zhen-ming Liu, Ke-qiang Fan, Chang-kang Huang, Ping Wei, Jian-feng Pei, Shi-yong Liu, Hao Chen. Non-peptidic Inhibitors of SARS coronavirus 3C-like proteinase and their applications. Chinese Patent. Serial No. ZL 200510086932.3.
2. Ying Liu, Lu-hua Lai, Ya-bing Feng, Lei Jia. An improved synthesis of a kind of phospholipase A2 inhibitors. Chinese Patent. Serial No. ZL 02153407.1.