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2014年发表论文





Light responses of primate and other mammalian cones.

Cao, L.-H.; Luo, D.-G.; Yau, K.-W.

Proc. Natl. Acad. Sci. U. S. A. 2014, 111, (7), 2752-2757. [PubMed]



Community detection for networks with unipartite and bipartite structure.

Chang, C.; Tang, C.

New Journal of Physics 2014, 16. [PubMed]



Break CDK2/Cyclin E1 Interface Allosterically with Small Peptides.

Chen, H.; Zhao, Y.; Li, H.; Zhang, D.; Huang, Y.; Shen, Q.; Van Duyne, R.; Kashanchi, F.; Zeng, C.; Liu, S.

PLoS One 2014, 9, (10). [PubMed]



Protein-Protein Interface Analysis and Hot Spots Identification for Chemical Ligand Design.

Chen, J.; Ma, X.; Yuan, Y.; Pei, J.; Lai, L.

Curr. Pharm. Des. 2014, 20, (8), 1192-1200. [PubMed]



Correlation between Oncogenic Mutations and Parameter Sensitivity of the Apoptosis Pathway Model.

Chen, J.; Yue, H.; Ouyang, Q.

PLoS Comput. Biol. 2014, 10, (1). [PubMed]



RNA Editome in Rhesus Macaque Shaped by Purifying Selection.

Chen, J.-Y.; Peng, Z.; Zhang, R.; Yang, X.-Z.; Tan, B. C.-M.; Fang, H.; Liu, C.-J.; Shi, M.; Ye, Z.-Q.; Zhang, Y. E.; Deng, M.; Zhang, X.; Li, C.-Y.

Plos Genetics 2014, 10, (4). [PubMed]



Cab45S inhibits the ER stress-induced IRE1-JNK pathway and apoptosis via GRP78/BiP.

Chen, L.; Xu, S.; Liu, L.; Wen, X.; Xu, Y.; Chen, J.; Teng, J.

Cell Death Dis. 2014, 5. [PubMed]



Differential simulated annealing: a robust and efficient global optimization algorithm for parameter estimation of biological networks.

Dai, Z.; Lai, L.

Molecular Biosystems 2014, 10, (6), 1385-1392. [PubMed]



Studies of the drug resistance response of sensitive and drug-resistant strains in a microfluidic system.

Jiang, X.; Kang, Y.; Pan, X.; Yu, J.; Ouyang, Q.; Luo, C.

Integrative Biology 2014, 6, (2), 143-151. [PubMed]



Pump-free multi-well-based microfluidic system for high-throughput analysis of size-control relative genes in budding yeast.

Kang, X.; Jiang, L.; Chen, X.; Yuan, H.; Luo, C.; Ouyang, Q.

Integrative Biology 2014, 6, (7), 685-693. [PubMed]



Square Turing patterns in reaction-diffusion systems with coupled layers.

Li, J.; Wang, H.; Ouyang, Q.

Chaos 2014, 24, (2). [PubMed]



Advantages of proteins being disordered.

Liu, Z.; Huang, Y.

Protein Sci. 2014, 23, (5), 539-550. [PubMed]



Multiple mechanisms determine the order of APC/C substrate degradation in mitosis.

Lu, D.; Hsiao, J. Y.; Davey, N. E.; Van Voorhis, V. A.; Foster, S. A.; Tang, C.; Morgan, D. O.

J. Cell Biol. 2014, 207, (1), 23-39. [PubMed]



Constructing the Energy Landscape for Genetic Switching System Driven by Intrinsic Noise.

Lv, C.; Li, X.; Li, F.; Li, T.

PLoS One 2014, 9, (2). [PubMed]



Systems Biology Brings New Dimensions for Structure-Based Drug Design.

Pei, J.; Yin, N.; Ma, X.; Lai, L.

J. Am. Chem. Soc. 2014, 136, (33), 11556-11565. [PubMed]



Discovery of Novel Secretory Phospholipase A(2) Inhibitors Using Virtual Screen.

Qiu, S.; Chen, F.; Liu, Y.; Lai, L.

Chem. Biol. Drug Des. 2014, 84, (2), 216-222. [PubMed]



Development of 3,5-dinitrobenzoate-based 5-lipoxygenase inhibitors.

Shang, E.; Liu, Y.; Wu, Y.; Zhu, W.; He, C.; Lai, L.

Bioorg. Med. Chem. 2014, 22, (8), 2396-2402. [PubMed]



Benzo d isothiazole 1,1-dioxide derivatives as dual functional inhibitors of 5-lipoxygenase and microsomal prostaglandin E-2 synthase-1.

Shang, E.; Wu, Y.; Liu, P.; Liu, Y.; Zhu, W.; Deng, X.; He, C.; He, S.; Li, C.; Lai, L.

Bioorg. Med. Chem. Lett. 2014, 24, (12), 2764-2767. [PubMed]



De Novo Design of Multitarget Ligands with an Iterative Fragment-Growing Strategy.

Shang, E.; Yuan, Y.; Chen, X.; Liu, Y.; Pei, J.; Lai, L.

Journal of Chemical Information and Modeling 2014, 54, (4), 1235-1241. [PubMed]



Discovery of highly potent TNF alpha inhibitors using virtual screen.

Shen, Q.; Chen, J.; Wang, Q.; Deng, X.; Liu, Y.; Lai, L.

Eur. J. Med. Chem. 2014, 85, 119-126. [PubMed]



A PATHWAY-BASED MEAN-FIELD MODEL FOR E.COLI CHEMOTAXIS: MATHEMATICAL DERIVATION AND ITS HYPERBOLIC AND PARABOLIC LIMITS.

Si, G.; Tang, M.; Yang, X.

Multiscale Modeling & Simulation 2014, 12, (2), 907-926. [PubMed]



Costs and Benefits of Mutational Robustness in RNA Viruses.

Stern, A.; Bianco, S.; Yeh, M. T.; Wright, C.; Butcher, K.; Tang, C.; Nielsen, R.; Andino, R.

Cell Reports 2014, 8, (4), 1026-1036. [PubMed]



Dimensional reduction of a V1 ring model with simple and complex cells.

Wang, C.; Tao, L.

J. Comput. Neurosci. 2014, 37, (3), 481-492. [PubMed]



Discovery of Novel Allosteric Effectors Based on the Predicted Allosteric Sites for Escherichia coli D-3-Phosphoglycerate Dehydrogenase.

Wang, Q.; Qi, Y.; Yin, N.; Lai, L.

PLoS One 2014, 9, (4). [PubMed]



iDrug: a web-accessible and interactive drug discovery and design platform.

Wang, X.; Chen, H.; Yang, F.; Gong, J.; Li, S.; Pei, J.; Liu, X.; Jiang, H.; Lai, L.; Li, H.

Journal of Cheminformatics 2014, 6. [PubMed]



Imputing missing values for genetic interaction data.

Wang, Y.; Wang, L.; Yang, D.; Deng, M.

Methods 2014, 67, (3), 269-277. [PubMed]



The minimal alpha-crystallin domain of Mj Hsp 16.5 is functional at non-heat-shock conditions.

Xi, D.; Wei, P.; Zhang, C.; Lai, L.

Proteins-Structure Function and Bioinformatics 2014, 82, (7), 1156-1167. [PubMed]



Synergistic and Antagonistic Drug Combinations Depend on Network Topology.

Yi, N.; Ma, W.; Pei, J.; Ouyang, Q.; Tang, C.; Lai, L.

PLoS One 2014, 9, (4). [PubMed]



Molecular Interactions of Bacterial Chemoreceptor Assemblies.

Yu, D.-Q.; Tu, Y.-H.; Lai, L.-H.

Acta Physico-Chimica Sinica 2014, 30, (7), 1347-1353. [PubMed]



Discovery of binding proteins for a protein target using protein-protein docking-based virtual screening.

Zhang, C.; Tang, B.; Wang, Q.; Lai, L.

Proteins-Structure Function and Bioinformatics 2014, 82, (10), 2472-2482. [PubMed]



Programming a Pavlovian-like conditioning circuit in Escherichia coli.

Zhang, H.; Lin, M.; Shi, H.; Ji, W.; Huang, L.; Zhang, X.; Shen, S.; Gao, R.; Wu, S.; Tian, C.; Yang, Z.; Zhang, G.; He, S.; Wang, H.; Saw, T.; Chen, Y.; Ouyang, Q.

Nature Communications 2014, 5. [PubMed]



A protein engineered to bind uranyl selectively and with femtomolar affinity.

Zhou, L.; Bosscher, M.; Zhang, C.; Oezcubukcu, S.; Zhang, L.; Zhang, W.; Li, C. J.; Liu, J.; Jensen, M. P.; Lai, L.; He, C.

Nature Chemistry 2014, 6, (3), 236-241. [PubMed]



Angle sensing in magnetotaxis of Magnetospirillum magneticum AMB-1.

Zhu, X.; Ge, X.; Li, N.; Wu, L.-F.; Luo, C.; Ouyang, Q.; Tu, Y.; Chen, G.

Integrative Biology 2014, 6, (7), 706-713. [PubMed]



Characterizing the strand-specific distribution of non-CpG methylation in human pluripotent cells.

Guo, W.; Chung, W.-Y.; Qian, M.; Pellegrini, M.; Zhang, M. Q.

Nucleic Acids Res. 2014, 42, (5), 3009-3016. [PubMed]



Salt-Induced Stabilization of EIN3/EIL1 Confers Salinity Tolerance by Deterring ROS Accumulation in Arabidopsis.

Peng, J.; Li, Z.; Wen, X.; Li, W.; Shi, H.; Yang, L.; Zhu, H.; Guo, H.

Plos Genetics 2014, 10, (10). [PubMed]



Refining network reconstruction based on functional reliability.

Zhang, Y.; Ouyang, Q.; Geng, Z.

J. Theor. Biol. 2014, 353, 170-178. [PubMed]



Prediction of Translation Initiation Site in Bacterial and Archaeal Genomes.

Zhu, H.; Wang, Q.

Current Bioinformatics 2014, 9, (2), 155-165. [PubMed]