News

 

Congratulations to Yuan Yuan and Huan Hu   


On May 2017, Yuan Yuan and Huan Hu successfully defended their Ph.D. thesis. In the thesis research, Yuan Yuan constructed an inducible cell apoptosis system. By combining single-cell quantitative experiments with mathematical modeling, she unraveled the rational behind the apoptosis circuitry and came up with a criterion for the life-death cell fate. Huan Hu developed a new method for mammalian genomic loci labeling: BiFC-TALE, and realized the imaging of telomere and alpha-satellite sequences. Compared with previous methods, the system dramatically improved the Signal-to-Background-Ratio of gene labeling by firstly introducing BiFC technology to this field. Congratulations to Drs. Yuan and Hu!

 

 


Students enjoyed the Workshop in korea   


Xiaochan Xu, Huixia Ren and Xiang Liu attended the "A3-NIMS Joint Workshop on interdisciplinary Research Connecting Mathematics and Biology" from May 12 to 14 at Daejeon, Korea. The A3 funding strongly encourages research communication and collaboration between China, Japan and Korea (Asia 3 counties). This year the workshop was hosted by National Institute for Mathematical Sciences (NIMS) in Korea. During the 3 days of well-organized meeting, researchers presented their recent progress and engaged in active discussions in many interdisciplinary areas between mathematics and biology, such as computing, modeling, data analysis and dynamic systems etc. All the three students benefited a lot from interacting with other participants. In particular, they were given opportunities to present their own work at the meeting. They also enjoyed the multi-culture atmosphere, and the natural beauty and hot springs in Daejeon.

 

 


Wenjia Shi obtains her Ph.D. degree   


On December 2016, Wenjia Shi defended her Ph.D. thesis. As a Ph.D. candidate, she chose adaptation as aim function, to investigate the impact of regulatory rules and network size on the design principles of complex biological networks. She found these two factors bring in rich network "sub-types", which mainly affects the forms of the control node. Congratulations to Wenjia!

 

 


Mathias L. Heltberg Visiting TangLab   


Mathias L. Heltberg,a graduate student from Niels Bohr Institute, University of Copenhagen visited Tang Lab from the 10th to the 17th of November, 2016. He talked about his research on mode locking in NF-kB system. Students from Tang lab shared with Mathias their work and the Chinese culture.

 

 


Congratulations to graduating students   


This summer, Yao Zhao, Qi Liu, Xin Wang and Chang Chang defended their Ph.D. thesis, and Xin Wang was awarded the Excellent Graduate award. In the research, Yao Zhao built an ODE model of cell cycle regulatory network of budding yeast, focusing on the system’s global stability and bifurcations; Xin Wang quantitative studied the optimal growth of unicellular organisms; Qi Liu systematically studied the dynamics and metabolic properties of cellular quiescence state in fission yeast; Chang Chang have systematically investigated mutation dynamics of both high and low abundance based on accurate asexual population sequencing data from the views of fitness and epistasis. Congratulations to them!

 

 


Prof. Kim Sneppen Visiting TangLab   


Prof. Kim Sneppen from Niels Bohr Institute, University of Copenhagen visited Center for Quantitative Biology (CQB) and Tang Lab from the 8th to the 28th of April, 2016. During his visit, he gave two seminars on the Biological Physics research. He interacted intensively with CQB faculty members and students. Students from Tang lab shared with Prof. Sneppen ideas about science and Chinese culture, as well as food.

 

 


Graduate student Jiayin Hong visiting Kyoto University   


From Jan 6th to Mar 29th, 2016, Jiayin Hong went to Japan to collaborate with Prof. Li Liu's group at iCeMs, Kyoto University on distinct pluripotent stem cell states derived from different cell-matrix adhesion. Jiayin was responsible for constructing the mathematical model and theoretical analysis. Besides work, she became a big fan of sushi and ramen.

 

 


2015 CQB Annual Retreat   


2015 CQB Annual Retreat was held on January 17th, 2016, in the Lecture Hall of the College of Chemistry and Molecular Engineering of Peking University. The goal is to promote communication, interaction and cooperation among the research groups. The agenda includes annual report of CQB, 6 invited lectures and 51 presentations by graduate students and postdocs. More than 100 people attended the retreat.

 

 


Go skiing!   


Members from tanglab went skiing on January 7 th , 2016. How fast and furious it was!

 

 


Prof. Tang won "Best 10 Teachers" award   


In the second PKU “Best 10 Teachers” competition organized by the Graduate School, Prof. Tang is one of the ten winners. Congratulation!

 

 


Teacher’s Day   


Happy Teacher’s Day to Prof. Tang, Prof. Yang and Dr. Gong.

 

 


UCSB Summer School   


Shanshan Qin and Haojie Li attended the 3rd Santa Barbara advanced summer shool for quantitative biology from Aug 3 to Sept 5 at UC Santa Barbara. The aim of this course was to make progress towards filling the gap between cell and evolutionary biology. With well desigened reseach projects, this course combined state-of-the-art in vivo microscopy, bioinformatics analysis and theoretical modeling aimed at uncovering the evolutionary basis of cellular function and behavior at multiple scales. Druing the five-week intense course, Shanshan did two rounds of experimental rotation projects about embroygenesis of various insects and Haojie did two rounds theoretical rotation projects. They enjoyed the multi-culture atmosphere, and benefited a lot from interacting with other participants

 

 


Q-bio conference and UCSD Summer School   


From July 12th to August 9th, 2015, Wenjia Shi, Xiang Liu, Jiayin Hong and Peipei Yin attended the Q-Bio Summer School and Conference. They also visited the Harvard Medical School to see the lab alumni Dr. Wenzhe Ma and Dr. Xili Liu.

 

 


Summer school in Italy   


From July 19th to July 25th, 2015, Mingyue Zhang, Binghui Tian and Huixia Ren attended the summer school on bioinformatics and computational biology. The main and special guest lectures addressed the scope focusing on “Computational Dynamic Analysis of Biological Process”. Topics such as Biological Networks at different spatial scales, Evolutionary Game-Theoretic Models and Immune System Analysis involve intriguing problems. The three students enjoyed greatly.

 

 


Farewell and Welcome to TangLab!   


Zhang Zidong, Yan Jiawei and Zhou Yuansheng finished their undergraduate research training projects at TangLab, and they will further their graduate studies at Princeton, Harvard and UCSD in the coming years. Good luck to them! Two Ph.D. students and one postdoctoral researcher joined TangLab recently. Welcome Zhang Lu, Li Yanjun and Dr. Liu Hao!

 

 


Xianfeng Ping obtains her Ph.D. degree   


On June 2015, Xianfeng Ping defended her Ph.D. thesis. As a Ph.D. candidate, she carried out an exhaustive computational analysis on the network topologies that robustly execute the patterning functions of C. elegans VPCs. Congratulations to Xianfeng!

 

 


The Pathfinder   


Prof. Chao Tang, the Executive Dean of Academy for Advanced Interdisciplinary Studies, chatted about his research and education path with a group of students on April 2, 2015. About 20 students from various departments and research centers participated in the event. Prof. Tang shared his academic and research experience and his view on interdisciplinary sciences. The event was filled with lively dialog and laughter.

 

 


Dr. Huili Feng Visited Tang Lab   


Dr. Huili Feng from Washington University in St. Louis visited CQB (Center for Quantitative Biology) and Tang Lab on March 25, 2015. During her visit, she gave a seminar on “Small RNA Regulation of Quorum Sensing in Vibrios”. She talked with CQB faculty members and students. Students from Tang lab shared with Dr. Feng ideas about science and life.

 

 


2015 CQB Annual Symposium   


CQB Annual Meeting was held on February 6th 2015, in the lecture hall of College of Chemistry and Molecular Engineering of Peking University. 10 students reported their research progress. A new year party was held at night, students and teachers participated and played games together. Happy new year!

 

 


Go skiing!   


Members from tanglab went skiing on January 17 th , 2015. How fast and furious it was, and welcome Peipei and Jiayin joining Tanglab!

 

 


HAPPY HOUR   


Tang Lab hosted a Happy Hour at 4th floor of the ISRC building on December 25, 2014. People from CQB got together to celebrate the new year's coming and share their research ideas. Happy New Year! Everyone!

 

 


Quantitative Biology: from Genes, Cells to Networks   


From October 13th to 17th, we attended the Cold Spring Harbor Asia conference: From Genes, Cells to Networks, which was held in Suzhou, China. The conference included eight oral sessions and one poster session covering the latest findings across many topics in quantitative biology. Social events throughout the conference provide ample opportunity for informal interactions. Professor Chao Tang gave an invited talk and, as one of the organizers, presented the posters prizes to winning students. Xin Wang was one of the winners. Congratulations!

 

 


Workshop on Systems Biology   


From September 7th to 9th, Workshop on Systems Biology was held at the lecture hall of Beijing International Center for Mathematical Research. This Workshop, including plenary lectures and poster presentations, provides a interdisciplinary forum for researchers to show their recent findings. Xin Wang won the First Prize in the poster session while Shanshan Qin won the Second Prize. Congratulations!

 

 


The Eighth q-bio Summer School and Conference   


From July 27th to August 16th, Xin Wang, Chang Chang and Yuan Yuan attended the 8th q-bio summer school and Conference. q-bio is famous for its advanced courses and annual conferences in quantitative biology.

 

 


2014 CQB Annual Symposium   


2014 CQB Annual Symposium was held on July 8th at the lecture Hall of College of Chemistry and Molecular Engineering. This symposium included work report of CQB, 4 invited speeches from Peng Chen, Fuchou Tang, Haiyan Liu, Guanghua Huang. 49 students’ research reports were also presented. Yuan Yuan, Shanshan Qin, Xin Wang and Chang Chang won the CQB Scholarships, while Zongmao Gao won Third Prize in the poster session. Congratulations!

 

 


Welcome to TangLab!   


In this summer of 2014, Sheng Huanjie from the School of Life Science and Xiong Liyang from the School of Physics finished their undergraduate research training projects at TangLab, and they will further their graduate studies at UC Berkley and UCSD in the coming years, respectively. Good luck to them and we are here waiting for your coming back with heavy harvest. Three Ph.D students from CQB and the School ofPhysics joined TangLab. Welcome Binhui Tian, Xiang Liu, and Yueming Zhang! Hope everyone has a good time in their experience at TangLab.

 

 


The first International Young Scholars Systems and Synthetic Biology Symposium   


The first International Young Scholars Systems and Synthetic Biology Symposium was held from June 23rd to June 25th at the CQB. 27 outstanding worldwide young scholars and about a hundred students and colleagues attended the meeting. Presentations, posters, lively discussions were focused on the advanced hot spots of related fields during the 3 days’ meeting. Cell cycle regulations, gene regulatory networks, dynamics of cell signalling transmission, cell development, new technologies and tools had gained extensive attention and energetic discussions.

 

 


“Breaking Barriers, from Physics to Biology” Conference   


The second conference “Breaking Barriers, from Physics to Biology” was successfully held in Xi’an on June 13rd-16th, 2014. During the conference, nearly forty scholars from around the world and a few graduate students got together and discussed the opportunities and challenges for physicists who are working on biological problems. They also use this occasion to celebrate Prof. Albert Libchaber’s 80th birthday and his inspiring and productive career in science. Prof. Tang gave a talk titled “Cell fate transformation”, Xin and Shanshan participated and presented posters in the meeting.

 

 


Prof. Don Kulasiri Visited Tang Lab   


Prof. Don Kulasiri from Centre for Advanced Computational Solutions (C-fACS) at Lincoln University, New Zealand visited CQB (Center for Quantitative Biology) and Tang Lab on April 21-24. During his visit, He gave a seminar on the Computational Systems Biology research at Lincoln University. He talked with CQB faculty members and Tang Lab students. Students from Tang lab shared with Prof. Kulasiri ideas about science, Chinese and New Zealand cultures, as well as food.

 

 


CLS Happy Hour   


CLS (Center for Life Sciences) students held "A Happy Hour" on April 15th in the Meeting Room of the Integrated Science Research Building. Profs. Yi Rao and Chao Tang participated in this event, discussing with the students about CLS's past, present and future. The happy hour lasted much longer than an hour and was filled with lively exchange and laughter.

 

 


The First IIAS-PKU Workshop ‘Strategies & Design Principles in Cellular Complex Systems’ was Successfully Held   


The First IIAS-PKU Workshop ‘Strategies & Design Principles in Cellular Complex Systems’ was held in Jerusalem, Israel during March 23rd to 26th, 2014. This workshop is jointly organized by the Center for Quantitative Biology, Peking University (PKU) and Israel Institute for Advanced Studies, Hebrew University (HBU). Many professors from PKU and Israel attended the workshop, including Chao Tang, Yuhai Tu and Yiyan Huang from PKU, Uri Alon and Naama Barkai from Weizmann Institute, Michal Linial, Sigal Ben-Yehuda and Nir Friedman from HBU. Nine PKU students and tens of Israel students participated in the workshop.

 

 


APS March meeting   


2014 APS( American Physical Society) March meeting was held from March 3rd to 7th in Denver, Colorado. Thousands of physicists, scientists, and journalists from around the world attended the meeting. It offered valuable opportunities for presenting research, sharing insights, and networking. Biophysics, Systems biology, Physics in cancer sessions were included. Shanshan and Wenjia participated and presented posters in this meeting. Professor Tang gave an invited lecture on "Reliable cell cycle commitment in budding yeast is ensured by signal integration”.

 

 


Go Skiing!   


Tang Lab and Wei Lab went skiing together on January 19th, 2014. Admiring the snow-covered mountain and breathing the fresh air fully recharged our batteries! Also, welcome Xiaochan and Teng for joining Tang Lab!

 

 


New Year’s Eve Happy Hour!   


Tang Lab hosted a New Year’s Eve Happy Hour at 4th floor of the ISRC building on December 31st, 2013. People from our lab, Wei Lab and Luo Lab got together to celebrate the new year's coming and share their research ideas. Happy New Year! Everyone!

 

 


Prof. Tang voted "The Most Popular Teacher of 2013"   


Students at the School of Life Sciences voted to select 5 teachers to received the honor-The Most Popular Teacher of 2013. The award was given on December 22rd in the New Year's Gala of SLS. Congratulations to Prof. Tang!

 

 


XiaoJing Yang Gave her talk at 6th Beijing Yeast Club   


On December 21st, 2013, 6th Beijing Yeast Club was held at No. 143 Lecture Hall, Life Science Building, Tsinghua University. Some graduate students from Tanglab attended the meeting. Researcher Xiaojing Yang gave her talk on "Design Principles of the Yeast G1/S Switch".

 

 


The Microfluidics and Quantitative Biology International Conference   


The Microfluidics and Quantitative Biology International Conference was held in Peking University from October 16th to 19th. Speakers from around the world reported their work in using microfluidics as a powerful tool to investigate biological and medical questions, and addressed issues such as potential new directions for microfluidics approaches in quantitative biology and challenges in microfluidic technology.

 

 


Attended The Autumn Conference of Chinese Physical Society   


The Autumn Conference of Chinese Physical Society was held from September 12th to 15th. More than 2000 people attended, including Nobel Laureate Samuel Chao Chung Ting. Zhao Yao and 11 other students from our lab attended the conference. At the conference, Lingli Jiang and Shanshan Qin received Poster Award. As an invited speaker, Professor Tang gave a lecture on the Physics of Life in the session of Statistical Physics and Complex Systems.

 

 


Happy Teacher’s Day!   


Happy Teacher’s Day to Profs. Tang and Yang!

 

 


Happy Hour by CLS   


Eleven laboratories from the School of Life Sciences, the Department of Psychology, BIOPIC and the Center of Quantitative Biology have now settled down in the new Equipment Building. Happy Hour, which is held by the Center for Life Sciences, aims to promote communication between different labs. All professors and students are welcome. It will be held biweekly from 16:00 – 17:00 on Friday afternoon in the Equipment Building.

 

 


Postdoctor Recruitment   


Postdoctoral positions are available for highly motivated candidates with theoretical, experimental, or computational background. Interested candidates should contact us at xiaojingpku_at_gmail.com.

 

 


14th International Conference on Systems Biology   


The 14th International Conference on Systems Biology was held in Copenhagen from Aug 30th to Sep 3rd. Five graduate students from our lab (Yao Zhao, Xin Wang, Xianfeng Ping, Chang Chang, and Yimiao Qu) attended this meeting. At the meeting, they presented posters to communicate with other scientists from all over the world.

 

 


CCTV13 Reported the Collaboration in Cellular Reprogramming   


On August 13th, CCTV13 reported an innovative breakthrough in the methods and mechanisms of cellular reprogramming by Deng Lab and Tang Lab. See the video here: http://162.105.160.8/vedio/.

 

 


7th Q-bio summer school   


From July 20th to August 6th, Zongmao Gao attended a computational neuroscience course of the 7th Q-bio summer school at UCSD. Q-bio is famous for its advanced courses and topics in quantitative biology. Xin Wang and Xianfeng Ping also attended last summer.

 

 


2013 CQB Annual Symposium   


From July 16th-20th, group members from Tang Lab attended the 2013 CQB Annual Symposium. The activities included research presentation, team challenge and brainstorming. Qi Liu and Zongmao Gao won the Third-Prize CQB Scholarship, while Zhiyuan Li won Second Prize in the poster session.

 

 


Lingli Jiang Obtains her Ph.D. degree   


On June 2013, Lingli Jiang defended her Ph.D. thesis. She will continue her post-doctoral study at Tang Lab. Congratulations to Lingli!

 

 


Induction of Pluripotency in Mouse Somatic Cells   


Induction of pluripotency in somatic cells is one of the central topics in stem cell research. Recently, Deng Lab and Tang Lab of Peking University collaborated in achieving an innovative breakthrough in the methods and mechanism of cellular reprogramming. They discovered that the conventional lineage specifiers are able to promote the induction of stem cells under certain conditions. Furthermore, they used computational methods to elucidate the underlying principles of this observation: the state of the cell-fate determination network needs to reach a balance in order to realize pluripotency. A “seesaw model” of cell fate determination was proposed, and following experiments validated the prediction of this model. The research paper is published in the journal Cell. (Shu et al., Induction of Pluripotency in Mouse Somatic Cells with Lineage Specifiers. (2013). Cell 153, 963-975)

 

 


Winter q-bio meeting   


From February 18th-21st, 2013, Prof. Chao Tang was invited to the first Winter q-bio meeting. Graduate students Lingli Jiang and Zhiyuan Li also attended the meeting. The meeting brings together scientists and engineers who are interested in all areas of q-bio. The focus this year was on Synthetic Biology, with about half of the invited speakers chosen being renowned experts in that area. A meeting report was published in the journal of Quantitative Biology( Please visit http://link.springer.com/article/10.1007/s40484-013-0017-z).

 

 


Simone Bianco's Paper Chosen as Editor's Choice   


Simone Bianco's paper was recently chosen as Editor's Choice of the Bulletin of Mathematical Biology for 2012. Eric Forgoston, Simone Bianco et al., Maximal Sensitive Dependence and the Optimal Path to Epidemic Extinction (2011).Bulletin of Mathematical Biology http://www.springer.com/?SGWID=0-0-1500-1967403-0&cm_mmc=AD-_-Journal-_-SOC17538_V1-_-0.

 

 


Prof. Tang Featured on the Cover Page of CHISA   


Magazines CHISA interviewed Professor Chao Tang and reported his research both in USA and China.

 

 


Prof. Tang Featured on the Cover Page of Scientific Chinese   


Magazines Scientific Chinese interviewed Professor Chao Tang and reported his research both in USA and China.

 

 


The core topology of cell polarization   


Self-organizing cell polarization is a common function of biological systems. Tang Lab collaborated with Wendell Lim’s Lab at UCSF to identify and experimentally verify core network topologies responsible for this function. The work was published in Cell (Chau et al., Designing synthetic regulatory networks capable of self-organizing cell polarization. (2012). Cell 151, 320-332) .

 

 


The Joint Symposium on Systems Biology between PKU and University of Toroto   


The Joint Symposium on Systems Biology between Peking University (PKU) and the University of Toronto (U of T) was held on Oct 19th-21st, 2012 in Beijing, China. Aiming to explore mutual interests and to develop future collaborations, the symposium was co-organized by PKU Center for Quantitative Biology (CQB), PKU Institute of Systems Biomedicine (ISB), and the Department of Molecular Genetics (MoGen) at University of Toronto.