Start	End	Path	Indirect or Direct	Datatype of start	Datatype of end	p.kruskal(start)	p.kruskal(end)	DM-DS vs HC(start)	DM-LS vs HC(start)	DM-LS vs DM-DS(start)	DM-DS vs HC(end)	DM-LS vs HC(end)	DM-LS vs DM-DS(end)	group
Blautia	Visfatin	Blautia+Visfatin	Direct	Genus	DM-associated hormones	1.36E-05	0.0229	up	dn	dn	dn	no	up	DM-DS
Parabacteroides	Visfatin	Parabacteroides+TXB2+blood+Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	DM-DS
Parabacteroides	Visfatin	Parabacteroides-16:0/18:2-PI+blood-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	DM-DS
Parabacteroides	Visfatin	Parabacteroides+16:0/22:6-PC+blood+Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	DM-DS
Parabacteroides	Visfatin	Parabacteroides+20:5/18:0-PC+blood+Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	DM-DS
Parabacteroides	Visfatin	Parabacteroides+18:1/20:4-PC+blood+Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	DM-DS
Parabacteroides	Visfatin	Parabacteroides-18:1/18:1-PE+blood-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+L-Phenylalanine+blood+MUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+Glycolysis / Gluconeogenesis+mTOR signaling pathway-Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+Glycolysis / Gluconeogenesis+EGFR tyrosine kinase inhibitor resistance-Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+Glycolysis / Gluconeogenesis+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+L-Tyrosine+blood-TXB2+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+GCDCA+stool-TXB2+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+L-Proline+blood-TXB2+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+GCDCA+stool+16:0/16:1-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+L-Glutamic acid+blood+L-Glutamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+GCDCA+stool-d18:1-20:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+GCDCA+stool+20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+CDCA+stool+20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+L-Glutamic acid+blood+PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+Glycolysis / Gluconeogenesis-Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea-20:1+blood+TMAO+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+L-Glutamic acid+blood+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+L-Phenylalanine+blood+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+GCA+stool+DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+Glycolysis / Gluconeogenesis+HIF-1 signaling pathway-Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea-20:1+blood+Resistin+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+Glycolysis / Gluconeogenesis+Intestinal immune network for IgA production-Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+Carbon metabolism+Intestinal immune network for IgA production-Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Dorea	Visfatin	Dorea+L-Tyrosine+blood+Leptin-Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium-d18:1-14:0-SM+blood-Taurine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium-Phenylacetic acid+stool-GUDCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium-Phenylacetic acid+stool-16:0/16:1-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium+GCDCA+stool+16:0/16:1-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium-Phenylacetic acid+stool+TXB2+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium+GCDCA+stool-TXB2+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium-d18:1-14:0-SM+blood-Serine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium-d18:1-16:1-SM+blood-MUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium-d18:1-14:0-SM+blood-MUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium+PDGF-bb-Leptin-Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium-Phenylacetic acid+stool-20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium+GCDCA+stool+20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium-d18:1-16:1-SM+blood-Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium-d18:1-16:1-SM+blood-UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium-d18:1-14:0-SM+blood-UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium-d18:1-14:0-SM+blood-PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium-d18:1-14:0-SM+blood-Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium-Phenylacetic acid+stool+d18:1-20:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium+GCDCA+stool-d18:1-20:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium-d18:1-14:0-SM+blood-Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
Faecalibacterium	Visfatin	Faecalibacterium-d18:1-14:0-SM+blood-L-Asparagine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-DS
TUDCA+blood	Visfatin	TUDCA+blood-TXB2+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.0229	no	no	dn	dn	no	up	DM-DS
TUDCA+blood	Visfatin	TUDCA+blood+L-Phenylalanine+urine-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.0229	no	no	dn	dn	no	up	DM-DS
Bacteroides	Visfatin	Bacteroides+d18:1-18:0-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.000267	0.0229	dn	dn	up	dn	no	up	DM-DS
Bacteroides	Visfatin	Bacteroides+16:0/22:6-PC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.000267	0.0229	dn	dn	up	dn	no	up	DM-DS
Propionic acid+stool	Visfatin	Propionic acid+stool+d18:1-20:1-SM+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.0229	dn	no	up	dn	no	up	DM-DS
[Ruminococcus]	Visfatin	[Ruminococcus]-TXB2+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0679	0.0229	no	no	dn	dn	no	up	DM-DS
[Ruminococcus]	Visfatin	[Ruminococcus]+18:1/18:1-PE+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0679	0.0229	no	no	dn	dn	no	up	DM-DS
[Ruminococcus]	Visfatin	[Ruminococcus]+18:0/18:1-PE+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0679	0.0229	no	no	dn	dn	no	up	DM-DS
[Ruminococcus]	Visfatin	[Ruminococcus]-18:1/20:4-PC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0679	0.0229	no	no	dn	dn	no	up	DM-DS
[Ruminococcus]	Visfatin	[Ruminococcus]+16:0/18:2-PI+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0679	0.0229	no	no	dn	dn	no	up	DM-DS
[Ruminococcus]	Visfatin	[Ruminococcus]-18:1-LPC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0679	0.0229	no	no	dn	dn	no	up	DM-DS
[Ruminococcus]	Visfatin	[Ruminococcus]-18:0/20:5-PC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0679	0.0229	no	no	dn	dn	no	up	DM-DS
GUDCA+blood	Visfatin	GUDCA+blood-Visfatin	Direct	serum_bileacids	DM-associated hormones	0.0766	0.0229	no	no	dn	dn	no	up	DM-DS
UDCA+blood	Visfatin	UDCA+blood+L-Phenylalanine+urine-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0939	0.0229	no	no	dn	dn	no	up	DM-DS
Acetic acid+stool	Visfatin	Acetic acid+stool+Serine+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.0229	dn	no	no	dn	no	up	DM-DS
Acetic acid+stool	Visfatin	Acetic acid+stool+18:1-LPC+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.0229	dn	no	no	dn	no	up	DM-DS
Alistipes	Visfatin	Alistipes-Betaine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0114	0.0229	no	up	no	dn	no	up	DM-DS
Alistipes	Visfatin	Alistipes-Serine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0114	0.0229	no	up	no	dn	no	up	DM-DS
Butyricimonas	Visfatin	Butyricimonas-UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.17	0.0229	no	no	no	dn	no	up	DM-DS
Butyricimonas	Visfatin	Butyricimonas-Serine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.17	0.0229	no	no	no	dn	no	up	DM-DS
Butyricimonas	Visfatin	Butyricimonas-L-Asparagine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.17	0.0229	no	no	no	dn	no	up	DM-DS
Butyricimonas	Visfatin	Butyricimonas-MUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.17	0.0229	no	no	no	dn	no	up	DM-DS
Butyricimonas	Visfatin	Butyricimonas-L-Glutamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.17	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella-Inflammatory mediator regulation of TRP channels-UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella-d18:1-16:1-SM+blood-UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella-Inflammatory mediator regulation of TRP channels-Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella+Roseburia+16:0/18:2-PI+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella-d18:1-20:0-SM+blood+d18:1-20:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella+Roseburia+GUDCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella-18:2/20:4-PC+blood+EPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella-Inflammatory mediator regulation of TRP channels+HCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella-Inflammatory mediator regulation of TRP channels-Serine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella-Inflammatory mediator regulation of TRP channels-PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella-DL-Indole-3-lactic acid+urine-Leptin-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella-d18:1-16:1-SM+blood-Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella-d18:1-16:1-SM+blood-MUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella+Roseburia+16:0/16:1-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella+Roseburia-TXB2+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella+Roseburia+20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella-Renin secretion-DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella+Roseburia-AA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella-Renin secretion+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella-Endocrine and other factor-regulated calcium reabsorption+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella-Inflammatory mediator regulation of TRP channels+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella-Renin secretion-Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
Collinsella	Visfatin	Collinsella-Inflammatory mediator regulation of TRP channels-Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-DS
5-Hydroxytryptamine+urine	Visfatin	5-Hydroxytryptamine+urine+L-Phenylalanine+urine-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.171	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Viral carcinogenesis+DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Glucagon signaling pathway-DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Osteoclast differentiation+DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Dopaminergic synapse-DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Cellular senescence+DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Human papillomavirus infection+DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Apoptosis+DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Amphetamine addiction-DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Circadian entrainment-DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Aldosterone synthesis and secretion-DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Fc epsilon RI signaling pathway+DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+C-type lectin receptor signaling pathway+DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Prolactin signaling pathway+DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Th17 cell differentiation+DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Osteoclast differentiation+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Inflammatory mediator regulation of TRP channels-Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+NF-kappa B signaling pathway+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Insulin resistance+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Amphetamine addiction-Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Neurotrophin signaling pathway+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Chronic myeloid leukemia+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Toll-like receptor signaling pathway+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+RIG-I-like receptor signaling pathway+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Prostate cancer+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+C-type lectin receptor signaling pathway+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Prolactin signaling pathway+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+TNF signaling pathway+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Th17 cell differentiation+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+B cell receptor signaling pathway+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Glucagon signaling pathway+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Osteoclast differentiation-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Inflammatory mediator regulation of TRP channels+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Dopaminergic synapse+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Human papillomavirus infection-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Apoptosis-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+NF-kappa B signaling pathway-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Insulin resistance-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Amphetamine addiction+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Circadian entrainment+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Toll-like receptor signaling pathway-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+RIG-I-like receptor signaling pathway-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Aldosterone synthesis and secretion+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Fc epsilon RI signaling pathway-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+C-type lectin receptor signaling pathway-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Prolactin signaling pathway-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+TNF signaling pathway-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+B cell receptor signaling pathway-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Inflammatory mediator regulation of TRP channels-Serine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Dopaminergic synapse-TMAO+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Th17 cell differentiation+TMAO+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Dopaminergic synapse-MUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Aldosterone synthesis and secretion-MUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Viral carcinogenesis-GUDCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Osteoclast differentiation-GUDCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Cellular senescence-GUDCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Human papillomavirus infection-GUDCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Apoptosis-GUDCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Amphetamine addiction+GUDCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Fc epsilon RI signaling pathway-GUDCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Prolactin signaling pathway-GUDCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Glucagon signaling pathway+HCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Osteoclast differentiation-HCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Inflammatory mediator regulation of TRP channels+HCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Cellular senescence-HCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Amphetamine addiction+HCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Aldosterone synthesis and secretion+HCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Fc epsilon RI signaling pathway-HCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Glucagon signaling pathway-Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Inflammatory mediator regulation of TRP channels-Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+NF-kappa B signaling pathway+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Amphetamine addiction-Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Neurotrophin signaling pathway+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Chronic myeloid leukemia+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Toll-like receptor signaling pathway+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+RIG-I-like receptor signaling pathway+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Prostate cancer+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+C-type lectin receptor signaling pathway+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+TNF signaling pathway+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+B cell receptor signaling pathway+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Human papillomavirus infection+Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Hepatitis C+L-Glutamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Th17 cell differentiation+L-Glutamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+NF-kappa B signaling pathway-HIF-1 signaling pathway-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Viral carcinogenesis+PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Glucagon signaling pathway-PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Osteoclast differentiation+PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Inflammatory mediator regulation of TRP channels-PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Cellular senescence+PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Human papillomavirus infection+PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Apoptosis+PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Amphetamine addiction-PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Toll-like receptor signaling pathway+PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Aldosterone synthesis and secretion-PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+C-type lectin receptor signaling pathway+PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+B cell receptor signaling pathway+PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+NF-kappa B signaling pathway-mTOR signaling pathway-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Fc epsilon RI signaling pathway-L-Phenylalanine+urine-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Prostate cancer+8-HETE+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+TNF signaling pathway+8-HETE+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+IP-10+Leptin-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Chronic myeloid leukemia+Taurine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Prostate cancer+Taurine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+TNF signaling pathway+Taurine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+B cell receptor signaling pathway+Taurine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Viral carcinogenesis+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Glucagon signaling pathway-UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Osteoclast differentiation+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Inflammatory mediator regulation of TRP channels-UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Dopaminergic synapse-UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Cellular senescence+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Human papillomavirus infection+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Apoptosis+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+NF-kappa B signaling pathway+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Amphetamine addiction-UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Toll-like receptor signaling pathway+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+RIG-I-like receptor signaling pathway+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina-Aldosterone synthesis and secretion-UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Fc epsilon RI signaling pathway+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+C-type lectin receptor signaling pathway+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Sarcina	Visfatin	Sarcina+Th17 cell differentiation+DHA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Methanosphaera	Visfatin	Methanosphaera-Roseburia-TXB2+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Methanosphaera	Visfatin	Methanosphaera-Roseburia+16:0/16:1-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Methanosphaera	Visfatin	Methanosphaera-Roseburia-AA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Methanosphaera	Visfatin	Methanosphaera-Roseburia+GUDCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Methanosphaera	Visfatin	Methanosphaera-Roseburia+20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
Methanosphaera	Visfatin	Methanosphaera-Roseburia+16:0/18:2-PI+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.0703	0.0229	no	no	no	dn	no	up	DM-DS
iso-DCA+stool	Visfatin	iso-DCA+stool+Propionic acid+stool+d18:1-20:1-SM+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	DM-DS
LCA+stool	Visfatin	LCA+stool-UDCA+stool+18:0/20:3-PI+blood-EPA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	DM-DS
LCA+stool	Visfatin	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+20:3n6+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	DM-DS
LCA+stool	Visfatin	LCA+stool-UDCA+stool+18:0/20:3-PI+blood+20:3n6+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	DM-DS
LCA+stool	Visfatin	LCA+stool-UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	DM-DS
LCA+stool	Visfatin	LCA+stool-TDCA+stool-12-ketoDCA+blood+Ethanolamine+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	DM-DS
LCA+stool	Visfatin	LCA+stool-UDCA+stool+L-Tyrosine+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	DM-DS
LCA+stool	Visfatin	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+20:2/18:0-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	DM-DS
LCA+stool	Visfatin	LCA+stool-UDCA+stool+18:0/20:3-PI+blood+20:2/18:0-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	DM-DS
LCA+stool	Visfatin	LCA+stool-TDCA+stool-12-ketoDCA+blood-18:0/18:1-PE+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	DM-DS
LCA+stool	Visfatin	LCA+stool-UDCA+stool+L-Tyrosine+blood-TXB2+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	DM-DS
LCA+stool	Visfatin	LCA+stool-TDCA+stool-d18:1-16:0-SM+blood+d18:1-20:1-SM+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	DM-DS
LCA+stool	Visfatin	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:0/18:1-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	DM-DS
LCA+stool	Visfatin	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:0/20:3-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	DM-DS
LCA+stool	Visfatin	LCA+stool-TDCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	DM-DS
Akkermansia	Visfatin	Akkermansia-Cholinergic synapse+EPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	DM-DS
Akkermansia	Visfatin	Akkermansia-Cholinergic synapse+18:0/20:5-PC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	DM-DS
Akkermansia	Visfatin	Akkermansia-Cholinergic synapse+18:1/20:4-PC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	DM-DS
Akkermansia	Visfatin	Akkermansia+Proteoglycans in cancer-Serine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	DM-DS
Akkermansia	Visfatin	Akkermansia-Cytokine-cytokine receptor interaction+Serine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	DM-DS
Akkermansia	Visfatin	Akkermansia-Longevity regulating pathway-Intestinal immune network for IgA production-Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	DM-DS
Akkermansia	Visfatin	Akkermansia+Proteoglycans in cancer-Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	DM-DS
Akkermansia	Visfatin	Akkermansia+Proteoglycans in cancer-UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	DM-DS
Akkermansia	Visfatin	Akkermansia-Cholinergic synapse+TXB2+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	DM-DS
Akkermansia	Visfatin	Akkermansia-Cytokine-cytokine receptor interaction+16:1/16:0-PC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	DM-DS
Akkermansia	Visfatin	Akkermansia+Proteoglycans in cancer+L-Phenylalanine+urine-Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	DM-DS
Akkermansia	Visfatin	Akkermansia-Cytokine-cytokine receptor interaction-HCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	DM-DS
Akkermansia	Visfatin	Akkermansia+Proteoglycans in cancer-MUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	DM-DS
Akkermansia	Visfatin	Akkermansia+Proteoglycans in cancer-PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	DM-DS
Akkermansia	Visfatin	Akkermansia+Proteoglycans in cancer-Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	DM-DS
Bifidobacterium	Visfatin	Bifidobacterium+HIF-1 signaling pathway-Visfatin	Indirect	Genus	DM-associated hormones	0.105	0.0229	no	dn	no	dn	no	up	DM-DS
3-Hydroxytyramine hydrochloride+urine	Visfatin	3-Hydroxytyramine hydrochloride+urine+5-Hydroxytryptamine+urine+L-Phenylalanine+urine-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.288	0.0229	no	no	no	dn	no	up	DM-DS
Phenylacetyl L-GlutaMine+urine	Visfatin	Phenylacetyl L-GlutaMine+urine+Visfatin	Direct	urine_cometabolism	DM-associated hormones	0.0909	0.0229	up	no	no	dn	no	up	DM-DS
Ruminococcus	Visfatin	Ruminococcus+20:2/18:0-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.335	0.0229	no	no	no	dn	no	up	DM-DS
Ruminococcus	Visfatin	Ruminococcus+18:0/20:3-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.335	0.0229	no	no	no	dn	no	up	DM-DS
Ruminococcus	Visfatin	Ruminococcus+Leptin-Visfatin	Indirect	Genus	DM-associated hormones	0.335	0.0229	no	no	no	dn	no	up	DM-DS
Ruminococcus	Visfatin	Ruminococcus-EPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.335	0.0229	no	no	no	dn	no	up	DM-DS
Ruminococcus	Visfatin	Ruminococcus-18:3n3+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.335	0.0229	no	no	no	dn	no	up	DM-DS
GCDCA+blood	Visfatin	GCDCA+blood+GUDCA+blood-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	DM-DS
GCDCA+blood	Visfatin	GCDCA+blood-TXB2+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	DM-DS
GCDCA+blood	Visfatin	GCDCA+blood-Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	DM-DS
GCDCA+blood	Visfatin	GCDCA+blood+HCA+blood-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	DM-DS
ACA+blood	Visfatin	ACA+blood+EPA+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.0229	no	no	no	dn	no	up	DM-DS
DCA+stool	Visfatin	DCA+stool-L-Tryptophan+stool+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.0229	no	no	no	dn	no	up	DM-DS
DCA+stool	Visfatin	DCA+stool-L-Tryptophan+stool+8-HETE+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.0229	no	no	no	dn	no	up	DM-DS
DCA+stool	Visfatin	DCA+stool+HDCA+stool-16:0/20:4-PI+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.0229	no	no	no	dn	no	up	DM-DS
DCA+stool	Visfatin	DCA+stool-GCA+stool+DPA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.0229	no	no	no	dn	no	up	DM-DS
2-hydroxyhippuric acid+urine	Visfatin	2-hydroxyhippuric acid+urine-L-Tryptophan+urine-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.215	0.0229	no	no	no	dn	no	up	DM-DS
Hippuric acid+urine	Visfatin	Hippuric acid+urine-IL-6-IP-10+Leptin-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.361	0.0229	no	no	no	dn	no	up	DM-DS
Butyric acid+stool	Visfatin	Butyric acid+stool+L-Histidine+blood+TMAO+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.102	0.0229	dn	no	no	dn	no	up	DM-DS
Butyric acid+stool	Visfatin	Butyric acid+stool-16:0/20:5-PC+blood-Glycine+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.102	0.0229	dn	no	no	dn	no	up	DM-DS
Butyric acid+stool	Visfatin	Butyric acid+stool-ACA+blood+EPA+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.102	0.0229	dn	no	no	dn	no	up	DM-DS
Butyric acid+stool	Visfatin	Butyric acid+stool-16:0/20:5-PC+blood+EPA+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.102	0.0229	dn	no	no	dn	no	up	DM-DS
Butyric acid+stool	Visfatin	Butyric acid+stool-16:0/20:5-PC+blood-L-Asparagine+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.102	0.0229	dn	no	no	dn	no	up	DM-DS
Butyric acid+stool	Visfatin	Butyric acid+stool+L-Citrulline+blood+Taurine+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.102	0.0229	dn	no	no	dn	no	up	DM-DS
Butyric acid+stool	Visfatin	Butyric acid+stool+L-Histidine+blood+Taurine+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.102	0.0229	dn	no	no	dn	no	up	DM-DS
Butyric acid+stool	Visfatin	Butyric acid+stool+L-Histidine+blood+PUFA%+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.102	0.0229	dn	no	no	dn	no	up	DM-DS
Butyric acid+stool	Visfatin	Butyric acid+stool-16:0/20:5-PC+blood+16:0/22:6-PC+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.102	0.0229	dn	no	no	dn	no	up	DM-DS
Butyric acid+stool	Visfatin	Butyric acid+stool-16:0/20:5-PC+blood+18:0/20:5-PC+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.102	0.0229	dn	no	no	dn	no	up	DM-DS
4-hydroxybenzoic acid+stool	Visfatin	4-hydroxybenzoic acid+stool+L-Tryptophan+stool+Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.0229	no	dn	no	dn	no	up	DM-DS
4-hydroxybenzoic acid+stool	Visfatin	4-hydroxybenzoic acid+stool+L-Tryptophan+stool+8-HETE+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.0229	no	dn	no	dn	no	up	DM-DS
Turicibacter	Visfatin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-d18:1-18:0-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.269	0.0229	no	no	no	dn	no	up	DM-DS
Turicibacter	Visfatin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-d18:1-18:0-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.269	0.0229	no	no	no	dn	no	up	DM-DS
Turicibacter	Visfatin	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-d18:1-18:0-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.269	0.0229	no	no	no	dn	no	up	DM-DS
Turicibacter	Visfatin	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-d18:1-20:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.269	0.0229	no	no	no	dn	no	up	DM-DS
Turicibacter	Visfatin	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-d18:1-20:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.269	0.0229	no	no	no	dn	no	up	DM-DS
Turicibacter	Visfatin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.269	0.0229	no	no	no	dn	no	up	DM-DS
Turicibacter	Visfatin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.269	0.0229	no	no	no	dn	no	up	DM-DS
Turicibacter	Visfatin	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.269	0.0229	no	no	no	dn	no	up	DM-DS
GCA+blood	Visfatin	GCA+blood-Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.0229	no	no	no	dn	no	up	DM-DS
GCA+blood	Visfatin	GCA+blood+HCA+blood-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.0229	no	no	no	dn	no	up	DM-DS
GCA+blood	Visfatin	GCA+blood-Serine+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.0229	no	no	no	dn	no	up	DM-DS
ACA+stool	Visfatin	ACA+stool-L-Tryptophan+stool+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.0229	no	no	no	dn	no	up	DM-DS
ACA+stool	Visfatin	ACA+stool-L-Tryptophan+stool+8-HETE+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.0229	no	no	no	dn	no	up	DM-DS
ACA+stool	Visfatin	ACA+stool-L-Phenylalanine+stool+8-HETE+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.0229	no	no	no	dn	no	up	DM-DS
CDCA+blood	Visfatin	CDCA+blood-UFA%+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.0229	no	no	no	dn	no	up	DM-DS
CDCA+blood	Visfatin	CDCA+blood-Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.0229	no	no	no	dn	no	up	DM-DS
CDCA+blood	Visfatin	CDCA+blood+L-Phenylalanine+urine-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.0229	no	no	no	dn	no	up	DM-DS
CDCA+blood	Visfatin	CDCA+blood-Glycine+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.0229	no	no	no	dn	no	up	DM-DS
CDCA+blood	Visfatin	CDCA+blood-Ethanolamine+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.0229	no	no	no	dn	no	up	DM-DS
CDCA+blood	Visfatin	CDCA+blood+HCA+blood-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.0229	no	no	no	dn	no	up	DM-DS
CDCA+blood	Visfatin	CDCA+blood+GUDCA+blood-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.0229	no	no	no	dn	no	up	DM-DS
CDCA+blood	Visfatin	CDCA+blood-PUFA%+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.0229	no	no	no	dn	no	up	DM-DS
capric acid C6+blood	Visfatin	capric acid C6+blood-HCA+blood-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.433	0.0229	no	no	no	dn	no	up	DM-DS
Prevotella	Visfatin	Prevotella-L-Glutamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	DM-DS
TCA+blood	Visfatin	TCA+blood+TUDCA+blood-TXB2+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.339	0.0229	no	no	no	dn	no	up	DM-DS
TCA+blood	Visfatin	TCA+blood+TUDCA+blood+L-Phenylalanine+urine-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.339	0.0229	no	no	no	dn	no	up	DM-DS
iso-DCA+blood	Visfatin	iso-DCA+blood+L-Asparagine+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.0229	no	no	no	dn	no	up	DM-DS
HCA+stool	Visfatin	HCA+stool-HDCA+stool-16:0/20:4-PI+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	DM-DS
Roseburia	Visfatin	Roseburia-TXB2+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.495	0.0229	no	no	no	dn	no	up	DM-DS
Roseburia	Visfatin	Roseburia+16:0/16:1-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.495	0.0229	no	no	no	dn	no	up	DM-DS
Roseburia	Visfatin	Roseburia-AA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.495	0.0229	no	no	no	dn	no	up	DM-DS
Roseburia	Visfatin	Roseburia+GUDCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.495	0.0229	no	no	no	dn	no	up	DM-DS
Roseburia	Visfatin	Roseburia+20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.495	0.0229	no	no	no	dn	no	up	DM-DS
Roseburia	Visfatin	Roseburia+16:0/18:2-PI+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.495	0.0229	no	no	no	dn	no	up	DM-DS
12-ketoDCA+stool	Visfatin	12-ketoDCA+stool-MUFA%+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.0229	no	no	no	dn	no	up	DM-DS
GLCA+blood	Visfatin	GLCA+blood-MUFA+blood+MUFA%+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.0229	no	no	no	dn	no	up	DM-DS
L-Tryptophan+stool	Visfatin	L-Tryptophan+stool+Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.0229	no	no	no	dn	no	up	DM-DS
L-Tryptophan+stool	Visfatin	L-Tryptophan+stool+8-HETE+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.0229	no	no	no	dn	no	up	DM-DS
CA+blood	Visfatin	CA+blood+GUDCA+blood-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.0229	no	no	no	dn	no	up	DM-DS
CA+blood	Visfatin	CA+blood+HCA+blood-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.0229	no	no	no	dn	no	up	DM-DS
CA+blood	Visfatin	CA+blood-MUFA%+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.0229	no	no	no	dn	no	up	DM-DS
CA+blood	Visfatin	CA+blood-Serine+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.0229	no	no	no	dn	no	up	DM-DS
CA+blood	Visfatin	CA+blood-Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.0229	no	no	no	dn	no	up	DM-DS
CA+blood	Visfatin	CA+blood-UFA%+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.0229	no	no	no	dn	no	up	DM-DS
GUDCA+stool	Visfatin	GUDCA+stool+TUDCA+stool-14:0/18:2-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.0229	no	dn	no	dn	no	up	DM-DS
L-Phenylalanine+stool	Visfatin	L-Phenylalanine+stool+8-HETE+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.0229	no	no	no	dn	no	up	DM-DS
butyric acid C4+blood	Visfatin	butyric acid C4+blood+L-Ornithine+blood+Taurine+blood+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.407	0.0229	no	no	no	dn	no	up	DM-DS
GCA+stool	Visfatin	GCA+stool+DPA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.0229	no	no	no	dn	no	up	DM-DS
Coprococcus	Visfatin	Coprococcus-14:0/18:2-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.612	0.0229	no	no	no	dn	no	up	DM-DS
Indole-3-Acetic acid+urine	Visfatin	Indole-3-Acetic acid+urine+Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.657	0.0229	no	no	no	dn	no	up	DM-DS
Indole-3-Acetic acid+urine	Visfatin	Indole-3-Acetic acid+urine-L-Tryptophan+urine-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.657	0.0229	no	no	no	dn	no	up	DM-DS
Indole-3-Acetic acid+urine	Visfatin	Indole-3-Acetic acid+urine-L-Phenylalanine+urine-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.657	0.0229	no	no	no	dn	no	up	DM-DS
Oscillospira	Visfatin	Oscillospira-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.62	0.0229	no	no	no	dn	no	up	DM-DS
HCA+blood	Visfatin	HCA+blood-Visfatin	Direct	serum_bileacids	DM-associated hormones	0.544	0.0229	no	no	no	dn	no	up	DM-DS
iso-LCA+stool	Visfatin	iso-LCA+stool-TCA+stool+18:1/18:1-PE+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-DS
iso-LCA+stool	Visfatin	iso-LCA+stool-TCA+stool-18:1/20:4-PC+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-DS
iso-LCA+stool	Visfatin	iso-LCA+stool-TCA+stool+16:0/18:2-PI+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-DS
iso-LCA+stool	Visfatin	iso-LCA+stool-TCA+stool-18:0/20:5-PC+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-DS
iso-LCA+stool	Visfatin	iso-LCA+stool-TCA+stool-d18:1-20:1-SM+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-DS
iso-LCA+stool	Visfatin	iso-LCA+stool-TCA+stool-16:0/22:6-PC+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-DS
iso-LCA+stool	Visfatin	iso-LCA+stool-TCA+stool-EPA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-DS
iso-LCA+stool	Visfatin	iso-LCA+stool-TCA+stool+18:0/18:1-PE+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-DS
iso-LCA+stool	Visfatin	iso-LCA+stool-TCA+stool-TXB2+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-DS
DCA+blood	Visfatin	DCA+blood+L-Histidine+blood+TMAO+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.0229	no	no	no	dn	no	up	DM-DS
DCA+blood	Visfatin	DCA+blood+L-Histidine+blood+Taurine+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.0229	no	no	no	dn	no	up	DM-DS
DCA+blood	Visfatin	DCA+blood+nutriCA+blood-Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.0229	no	no	no	dn	no	up	DM-DS
DCA+blood	Visfatin	DCA+blood+L-Histidine+blood+PUFA%+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.0229	no	no	no	dn	no	up	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	Visfatin	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-14:0/18:2-PC+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.0229	no	no	no	dn	no	up	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	Visfatin	"3-(3,4-dihydroxyphenyl)propionic acid+urine+3-Hydroxy-L-kynurenine+urine+L-Phenylalanine+urine-Visfatin"	Indirect	urine_cometabolism	DM-associated hormones	0.0125	0.0229	up	up	no	dn	no	up	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	Visfatin	"3-(3,4-dihydroxyphenyl)propionic acid+urine+DL-Indole-3-lactic acid+urine-Leptin-Visfatin"	Indirect	urine_cometabolism	DM-associated hormones	0.0125	0.0229	up	up	no	dn	no	up	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	Visfatin	"3-(3,4-dihydroxyphenyl)propionic acid+urine+3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine-Visfatin"	Indirect	urine_cometabolism	DM-associated hormones	0.0125	0.0229	up	up	no	dn	no	up	DM-DS
nutriCA+blood	Visfatin	nutriCA+blood-Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.726	0.0229	no	no	no	dn	no	up	DM-DS
4-hydroxybenzoic acid+urine	Visfatin	4-hydroxybenzoic acid+urine+Indole-3-Acetic acid+urine-L-Phenylalanine+urine-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.52	0.0229	no	no	no	dn	no	up	DM-DS
4-hydroxybenzoic acid+urine	Visfatin	4-hydroxybenzoic acid+urine+Indole-3-Acetic acid+urine+Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.52	0.0229	no	no	no	dn	no	up	DM-DS
4-hydroxybenzoic acid+urine	Visfatin	4-hydroxybenzoic acid+urine+Indole-3-Acetic acid+urine-L-Tryptophan+urine-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.52	0.0229	no	no	no	dn	no	up	DM-DS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-GUDCA+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-DS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-20:3n6+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-DS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool-nutriCA+stool+20:3n6+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-DS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool-nutriCA+stool+18:0/18:1-PC+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-DS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool-nutriCA+stool+18:0/20:3-PC+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-DS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool-nutriCA+stool+20:2/18:0-PC+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-DS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+d18:1-20:1-SM+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-DS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool-nutriCA+stool-AA+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-DS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool-nutriCA+stool+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-DS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+TXB2+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-DS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-16:0/16:1-PC+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-DS
TCA+stool	Visfatin	TCA+stool+18:1/18:1-PE+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.0229	no	no	no	dn	no	up	DM-DS
TCA+stool	Visfatin	TCA+stool-18:1/20:4-PC+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.0229	no	no	no	dn	no	up	DM-DS
TCA+stool	Visfatin	TCA+stool-TXB2+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.0229	no	no	no	dn	no	up	DM-DS
TCA+stool	Visfatin	TCA+stool-EPA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.0229	no	no	no	dn	no	up	DM-DS
TCA+stool	Visfatin	TCA+stool+16:0/18:2-PI+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.0229	no	no	no	dn	no	up	DM-DS
TCA+stool	Visfatin	TCA+stool-d18:1-20:1-SM+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.0229	no	no	no	dn	no	up	DM-DS
TCA+stool	Visfatin	TCA+stool+18:0/18:1-PE+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.0229	no	no	no	dn	no	up	DM-DS
TCA+stool	Visfatin	TCA+stool-16:0/22:6-PC+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.0229	no	no	no	dn	no	up	DM-DS
TCA+stool	Visfatin	TCA+stool-18:0/20:5-PC+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.0229	no	no	no	dn	no	up	DM-DS
HDCA+stool	Visfatin	HDCA+stool-16:0/20:4-PI+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-p53 signaling pathway-Axon guidance-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Prostate cancer+8-HETE+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-TNF signaling pathway+8-HETE+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Chronic myeloid leukemia+Taurine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Prostate cancer+Taurine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-TNF signaling pathway+Taurine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Glycolysis / Gluconeogenesis+EGFR tyrosine kinase inhibitor resistance-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Glycolysis / Gluconeogenesis-Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-JAK-STAT signaling pathway+Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Non-small cell lung cancer+Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-NOD-like receptor signaling pathway-20:2/18:0-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+TCA+stool+16:0/18:2-PI+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-p53 signaling pathway-16:0/18:2-PI+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Spliceosome-16:0/18:2-PI+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Tight junction+16:0/18:2-PI+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Leukocyte transendothelial migration+16:0/18:2-PI+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-FoxO signaling pathway-16:0/18:2-PI+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+TCA+stool+18:0/18:1-PE+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Small cell lung cancer-18:0/18:1-PE+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Vascular smooth muscle contraction+18:0/18:1-PE+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Tight junction+18:0/18:1-PE+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-FoxO signaling pathway-18:0/18:1-PE+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-JAK-STAT signaling pathway-18:0/18:1-PE+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Non-small cell lung cancer-18:0/18:1-PE+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+TCA+stool-16:0/22:6-PC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-NOD-like receptor signaling pathway-18:0/20:3-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+TCA+stool-18:0/20:5-PC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Renin secretion-DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Circadian entrainment-DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Vascular smooth muscle contraction-DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-JAK-STAT signaling pathway+DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-NOD-like receptor signaling pathway+DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+TCA+stool-18:1/20:4-PC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+L-Methionine+blood+PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-NOD-like receptor signaling pathway+PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+TCA+stool+18:1/18:1-PE+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+L-Methionine+blood+MUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-NOD-like receptor signaling pathway+MUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+TCA+stool-EPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Progesterone-mediated oocyte maturation+EPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+TCA+stool-TXB2+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+TCA+stool-d18:1-20:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Proteasome-Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-PD-L1 expression and PD-1 checkpoint pathway in cancer+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Hepatitis B+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Chronic myeloid leukemia+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Prostate cancer+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Autophagy - animal+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Cytosolic DNA-sensing pathway+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-RIG-I-like receptor signaling pathway+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Small cell lung cancer+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Transcriptional misregulation in cancer+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-TNF signaling pathway+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-NOD-like receptor signaling pathway+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-NF-kappa B signaling pathway+Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Proteasome+HIF-1 signaling pathway-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Glycolysis / Gluconeogenesis+HIF-1 signaling pathway-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-NF-kappa B signaling pathway-HIF-1 signaling pathway-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Proteasome+mTOR signaling pathway-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Glycolysis / Gluconeogenesis+mTOR signaling pathway-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Autophagy - animal-mTOR signaling pathway-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-FoxO signaling pathway-mTOR signaling pathway-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-NF-kappa B signaling pathway-mTOR signaling pathway-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Vibrio cholerae infection+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Proteasome+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Hepatitis B-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Adherens junction+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Insulin resistance-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Glycolysis / Gluconeogenesis+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Gastric acid secretion+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Platinum drug resistance-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Renin secretion+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Autophagy - animal-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Regulation of actin cytoskeleton+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-RIG-I-like receptor signaling pathway-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Circadian entrainment+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Hippo signaling pathway+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Vascular smooth muscle contraction+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Tight junction+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-FoxO signaling pathway-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Thyroid hormone signaling pathway+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-ErbB signaling pathway-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-TNF signaling pathway-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-JAK-STAT signaling pathway-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Focal adhesion+Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-NOD-like receptor signaling pathway-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-NF-kappa B signaling pathway-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Carbon metabolism+Intestinal immune network for IgA production-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Adherens junction+Intestinal immune network for IgA production-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-p53 signaling pathway-Intestinal immune network for IgA production-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Glycolysis / Gluconeogenesis+Intestinal immune network for IgA production-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Hippo signaling pathway+Intestinal immune network for IgA production-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Tight junction+Intestinal immune network for IgA production-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Leukocyte transendothelial migration+Intestinal immune network for IgA production-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-FoxO signaling pathway-Intestinal immune network for IgA production-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-JAK-STAT signaling pathway-Intestinal immune network for IgA production-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Focal adhesion+Intestinal immune network for IgA production-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Hepatitis B-GUDCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-NOD-like receptor signaling pathway-GUDCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-PD-L1 expression and PD-1 checkpoint pathway in cancer+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Hepatitis B+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Chronic myeloid leukemia+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Insulin resistance+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Prostate cancer+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-T cell receptor signaling pathway+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Renin secretion-Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Hepatocellular carcinoma-Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Regulation of actin cytoskeleton-Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Cytosolic DNA-sensing pathway+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-RIG-I-like receptor signaling pathway+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Small cell lung cancer+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Hippo signaling pathway-Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Transcriptional misregulation in cancer+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Arrhythmogenic right ventricular cardiomyopathy-Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-TNF signaling pathway+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Focal adhesion-Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-NOD-like receptor signaling pathway+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-NF-kappa B signaling pathway+Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Hepatitis B+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-RIG-I-like receptor signaling pathway+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-Transcriptional misregulation in cancer+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+L-Methionine+blood+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-NOD-like receptor signaling pathway+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-NF-kappa B signaling pathway+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Adherens junction+18:0/18:1-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Hippo signaling pathway+18:0/18:1-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Arrhythmogenic right ventricular cardiomyopathy+18:0/18:1-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira+Thyroid hormone signaling pathway+18:0/18:1-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Lachnospira	Visfatin	Lachnospira-NOD-like receptor signaling pathway-18:0/18:1-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-DS
Fusobacterium	Visfatin	Fusobacterium-Intestinal immune network for IgA production-Visfatin	Indirect	Genus	DM-associated hormones	0.628	0.0229	no	no	no	dn	no	up	DM-DS
Fusobacterium	Visfatin	Fusobacterium-18:0/18:1-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.628	0.0229	no	no	no	dn	no	up	DM-DS
Fusobacterium	Visfatin	Fusobacterium-GUDCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.628	0.0229	no	no	no	dn	no	up	DM-DS
GCDCA+stool	Visfatin	GCDCA+stool+20:3n6+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.0229	no	dn	no	dn	no	up	DM-DS
GCDCA+stool	Visfatin	GCDCA+stool+16:0/16:1-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.0229	no	dn	no	dn	no	up	DM-DS
GCDCA+stool	Visfatin	GCDCA+stool-TXB2+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.0229	no	dn	no	dn	no	up	DM-DS
GCDCA+stool	Visfatin	GCDCA+stool-d18:1-20:1-SM+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.0229	no	dn	no	dn	no	up	DM-DS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:1-PC+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-DS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PC+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-DS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool-nutriCA+stool+20:3n6+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-DS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool-nutriCA+stool+20:2/18:0-PC+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-DS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool-nutriCA+stool-AA+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-DS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool-nutriCA+stool+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-DS
Odoribacter	Visfatin	Odoribacter+16:0/20:4-PI+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.798	0.0229	no	no	no	dn	no	up	DM-DS
Actinomyces	Visfatin	Actinomyces+Coprococcus-14:0/18:2-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.621	0.0229	no	no	no	dn	no	up	DM-DS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool-nutriCA+stool+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-DS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool-nutriCA+stool+18:0/18:1-PC+blood-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-DS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/16:1-PC+blood-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-DS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool-nutriCA+stool+18:0/20:3-PC+blood-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-DS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+L-Phenylalanine+stool+8-HETE+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-DS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool-nutriCA+stool-AA+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-DS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool+d18:1-20:1-SM+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-DS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool-GUDCA+blood-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-DS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool-nutriCA+stool+20:3n6+blood-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-DS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool-20:3n6+blood-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-DS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool-nutriCA+stool+20:2/18:0-PC+blood-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-DS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool+TXB2+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-DS
2-hydroxyphenylacetic acid+urine	Visfatin	2-hydroxyphenylacetic acid+urine-L-Phenylalanine+urine-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.763	0.0229	no	no	no	dn	no	up	DM-DS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool-nutriCA+stool-AA+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-DS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool+L-Phenylalanine+stool+8-HETE+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-DS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PC+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-DS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool-nutriCA+stool+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-DS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool-nutriCA+stool+18:0/18:1-PC+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-DS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool-nutriCA+stool+20:3n6+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-DS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool-nutriCA+stool+20:2/18:0-PC+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-DS
L-Tryptophan+urine	Visfatin	L-Tryptophan+urine-Visfatin	Direct	urine_cometabolism	DM-associated hormones	0.226	0.0229	no	no	no	dn	no	up	DM-DS
Caproic acid+stool	Visfatin	Caproic acid+stool-TCA+stool+18:0/18:1-PE+blood-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.882	0.0229	no	no	no	dn	no	up	DM-DS
Caproic acid+stool	Visfatin	Caproic acid+stool+Phenylacetic acid+stool+TXB2+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.882	0.0229	no	no	no	dn	no	up	DM-DS
Caproic acid+stool	Visfatin	Caproic acid+stool-TCA+stool-TXB2+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.882	0.0229	no	no	no	dn	no	up	DM-DS
Caproic acid+stool	Visfatin	Caproic acid+stool-TCA+stool-16:0/22:6-PC+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.882	0.0229	no	no	no	dn	no	up	DM-DS
Caproic acid+stool	Visfatin	Caproic acid+stool-TCA+stool+16:0/18:2-PI+blood-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.882	0.0229	no	no	no	dn	no	up	DM-DS
Caproic acid+stool	Visfatin	Caproic acid+stool-TCA+stool-18:0/20:5-PC+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.882	0.0229	no	no	no	dn	no	up	DM-DS
Caproic acid+stool	Visfatin	Caproic acid+stool+Phenylacetic acid+stool-20:3n6+blood-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.882	0.0229	no	no	no	dn	no	up	DM-DS
Caproic acid+stool	Visfatin	Caproic acid+stool-TCA+stool+18:1/18:1-PE+blood-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.882	0.0229	no	no	no	dn	no	up	DM-DS
Caproic acid+stool	Visfatin	Caproic acid+stool+Phenylacetic acid+stool-16:0/16:1-PC+blood-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.882	0.0229	no	no	no	dn	no	up	DM-DS
Caproic acid+stool	Visfatin	Caproic acid+stool-TCA+stool-18:1/20:4-PC+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.882	0.0229	no	no	no	dn	no	up	DM-DS
Caproic acid+stool	Visfatin	Caproic acid+stool-TCA+stool-EPA+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.882	0.0229	no	no	no	dn	no	up	DM-DS
Caproic acid+stool	Visfatin	Caproic acid+stool-GCA+stool+DPA+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.882	0.0229	no	no	no	dn	no	up	DM-DS
Caproic acid+stool	Visfatin	Caproic acid+stool+Phenylacetic acid+stool+d18:1-20:1-SM+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.882	0.0229	no	no	no	dn	no	up	DM-DS
Caproic acid+stool	Visfatin	Caproic acid+stool-TCA+stool-d18:1-20:1-SM+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.882	0.0229	no	no	no	dn	no	up	DM-DS
Caproic acid+stool	Visfatin	Caproic acid+stool+Phenylacetic acid+stool-GUDCA+blood-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.882	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella+AMPK signaling pathway-DPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella-Yersinia infection-GUDCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella-Yersinia infection+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella-Yersinia infection+PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella+Phosphatidylinositol signaling system-PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella+AMPK signaling pathway+HCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella-Yersinia infection-HCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella+Phosphatidylinositol signaling system+HCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella-Influenza A-HCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella+nutriCA+stool+20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella+Phosphatidylinositol signaling system-Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella+nutriCA+stool+20:2/18:0-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella+Phosphatidylinositol signaling system-Taurine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella+nutriCA+stool-AA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella+nutriCA+stool+18:0/18:1-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella+AMPK signaling pathway-Serine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella-Yersinia infection+Serine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella+nutriCA+stool+Leptin-Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Eggerthella	Visfatin	Eggerthella+nutriCA+stool+18:0/20:3-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	DM-DS
Anaerotruncus	Visfatin	Anaerotruncus-Ruminococcus+20:2/18:0-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.904	0.0229	no	no	no	dn	no	up	DM-DS
Anaerotruncus	Visfatin	Anaerotruncus-Ruminococcus+18:0/20:3-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.904	0.0229	no	no	no	dn	no	up	DM-DS
Anaerotruncus	Visfatin	Anaerotruncus-Ruminococcus+Leptin-Visfatin	Indirect	Genus	DM-associated hormones	0.904	0.0229	no	no	no	dn	no	up	DM-DS
Anaerotruncus	Visfatin	Anaerotruncus-Ruminococcus-EPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.904	0.0229	no	no	no	dn	no	up	DM-DS
Anaerotruncus	Visfatin	Anaerotruncus-Ruminococcus-18:3n3+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.904	0.0229	no	no	no	dn	no	up	DM-DS
Anaerostipes	Visfatin	Anaerostipes+L-Tryptophan+urine-Visfatin	Indirect	Genus	DM-associated hormones	0.568	0.0229	no	no	no	dn	no	up	DM-DS
TUDCA+stool	Visfatin	TUDCA+stool-14:0/18:2-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.0229	no	no	no	dn	no	up	DM-DS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool-20:3n6+blood-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-DS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+L-Phenylalanine+stool+8-HETE+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-DS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool+TXB2+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-DS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool-GUDCA+blood-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-DS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/16:1-PC+blood-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-DS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool+d18:1-20:1-SM+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-DS
Paraprevotella	Visfatin	Paraprevotella+L-Phenylalanine+urine-Visfatin	Indirect	Genus	DM-associated hormones	0.118	0.0229	no	no	no	dn	no	up	DM-DS
Homovanillic acid+urine	Visfatin	Homovanillic acid+urine-IP-10+Leptin-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.45	0.0229	no	no	no	dn	no	up	DM-DS
TDCA+blood	Visfatin	TDCA+blood-IP-10+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.155	0.0229	no	up	no	dn	no	up	DM-DS
DL-Indole-3-lactic acid+urine	Visfatin	DL-Indole-3-lactic acid+urine-Leptin-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.00552	0.0229	up	up	no	dn	no	up	DM-DS
Phenaceturic acid+urine	Visfatin	Phenaceturic acid+urine+Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.737	0.0229	no	no	no	dn	no	up	DM-DS
¦Ø-MCA+stool	Visfatin	¦Ø-MCA+stool-L-Tryptophan+stool+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.0229	no	no	no	dn	no	up	DM-DS
¦Ø-MCA+stool	Visfatin	¦Ø-MCA+stool+CDCA+stool+20:3n6+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.0229	no	no	no	dn	no	up	DM-DS
¦Ø-MCA+stool	Visfatin	¦Ø-MCA+stool-L-Phenylalanine+stool+8-HETE+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.0229	no	no	no	dn	no	up	DM-DS
¦Ø-MCA+stool	Visfatin	¦Ø-MCA+stool-L-Tryptophan+stool+8-HETE+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.0229	no	no	no	dn	no	up	DM-DS
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool+d18:1-20:1-SM+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	DM-DS
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool-GUDCA+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	DM-DS
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool-16:0/16:1-PC+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	DM-DS
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool+TXB2+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	DM-DS
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool-20:3n6+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	"Gemmiger-12,13-EPOME+blood+16:0/18:2-PI+blood-Visfatin"	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	"Gemmiger-12,13-EPOME+blood+18:0/18:1-PE+blood-Visfatin"	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	"Gemmiger-12,13-EPOME+blood+18:1/18:1-PE+blood-Visfatin"	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+Colorectal cancer+HCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+PI3K-Akt signaling pathway+HCA+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	"Gemmiger-12,13-EPOME+blood-TMAO+blood+Visfatin"	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger-L-Threonine+blood+TMAO+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+Pathways in cancer-16:0/20:4-PI+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	"Gemmiger-12,13-EPOME+blood-d18:1-20:1-SM+blood+Visfatin"	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+d18:1-16:0-SM+blood+d18:1-20:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+d18:0-16:0-SM+blood+d18:1-20:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+Colorectal cancer-16:1/16:0-PC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+Central carbon metabolism in cancer-16:1/16:0-PC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+Colorectal cancer-PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+Colorectal cancer-MUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger-L-Threonine+blood+MUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+Pathways in cancer+18:1-LPC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	"Gemmiger-12,13-EPOME+blood-18:1-LPC+blood+Visfatin"	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+Colorectal cancer+L-Phenylalanine+urine-Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+Colorectal cancer-L-Asparagine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger-L-Threonine+blood+Taurine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+Central carbon metabolism in cancer-Taurine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+Colorectal cancer-UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+Colorectal cancer-Serine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger-L-Threonine+blood+Serine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+Central carbon metabolism in cancer-Serine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger-L-Threonine+blood-L-Tryptophan+urine-Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+Central carbon metabolism in cancer+Leptin-Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+Central carbon metabolism in cancer-Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+PI3K-Akt signaling pathway-Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
Gemmiger	Visfatin	Gemmiger+ErbB signaling pathway-Coronavirus disease - COVID-19-Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool-Phenylacetic acid+stool-20:3n6+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+16:0/20:3-PC+blood+20:3n6+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool-Phenylacetic acid+stool-16:0/16:1-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool-Phenylacetic acid+stool+d18:1-20:1-SM+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+16:0/18:1-PC+blood+16:1/16:0-PC+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+16:0/18:1-PC+blood+Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool-Phenylacetic acid+stool-GUDCA+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+16:0/20:3-PC+blood+18:0/18:1-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool-Phenylacetic acid+stool+TXB2+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+L-Tyrosine+blood-TXB2+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+16:0/20:3-PC+blood+18:0/20:3-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+16:0/20:3-PC+blood+20:2/18:0-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+L-Methionine+blood+MUFA%+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+L-Lysine+blood+MUFA%+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+L-Isoleucine+blood+MUFA%+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+L-Phenylalanine+blood+MUFA%+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+L-Methionine+blood+PUFA%+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+L-Lysine+blood+PUFA%+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+L-Tyrosine+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+IP-10+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+L-Methionine+blood+UFA%+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+L-Lysine+blood+UFA%+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+L-Phenylalanine+blood+UFA%+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool+L-Lysine+blood+Taurine+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+stool	Visfatin	GDCA+stool-20:4/18:0-PE+blood-L-Glutamine+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-DS
Methanobrevibacter	Visfatin	Methanobrevibacter-Cystine+blood+L-Asparagine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.629	0.0229	no	no	no	dn	no	up	DM-DS
Methanobrevibacter	Visfatin	Methanobrevibacter+d18:1-14:0-SM+blood-L-Asparagine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.629	0.0229	no	no	no	dn	no	up	DM-DS
Methanobrevibacter	Visfatin	Methanobrevibacter+d18:1-14:0-SM+blood-Taurine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.629	0.0229	no	no	no	dn	no	up	DM-DS
Methanobrevibacter	Visfatin	Methanobrevibacter-Cystine+blood+MUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.629	0.0229	no	no	no	dn	no	up	DM-DS
Methanobrevibacter	Visfatin	Methanobrevibacter+d18:1-14:0-SM+blood-MUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.629	0.0229	no	no	no	dn	no	up	DM-DS
Methanobrevibacter	Visfatin	Methanobrevibacter-Cystine+blood+PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.629	0.0229	no	no	no	dn	no	up	DM-DS
Methanobrevibacter	Visfatin	Methanobrevibacter+d18:1-14:0-SM+blood-PUFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.629	0.0229	no	no	no	dn	no	up	DM-DS
Methanobrevibacter	Visfatin	Methanobrevibacter-Cystine+blood+UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.629	0.0229	no	no	no	dn	no	up	DM-DS
Methanobrevibacter	Visfatin	Methanobrevibacter+d18:1-14:0-SM+blood-UFA%+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.629	0.0229	no	no	no	dn	no	up	DM-DS
Methanobrevibacter	Visfatin	Methanobrevibacter-Alcoholism-L-Phenylalanine+urine-Visfatin	Indirect	Genus	DM-associated hormones	0.629	0.0229	no	no	no	dn	no	up	DM-DS
Methanobrevibacter	Visfatin	Methanobrevibacter+d18:1-14:0-SM+blood-Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.629	0.0229	no	no	no	dn	no	up	DM-DS
Methanobrevibacter	Visfatin	Methanobrevibacter+d18:1-14:0-SM+blood-Serine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.629	0.0229	no	no	no	dn	no	up	DM-DS
Methanobrevibacter	Visfatin	Methanobrevibacter+d18:1-14:0-SM+blood-Glycine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.629	0.0229	no	no	no	dn	no	up	DM-DS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool+TUDCA+stool-14:0/18:2-PC+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-DS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool-nutriCA+stool+20:2/18:0-PC+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-DS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool-UDCA+blood+L-Phenylalanine+urine-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-DS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool+9-HODE+blood+Phenylacetyl L-GlutaMine+urine+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-DS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool-nutriCA+stool+20:3n6+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-DS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool+9-HODE+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-DS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool-nutriCA+stool+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-DS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool-nutriCA+stool+18:0/18:1-PC+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-DS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool-18:2/20:4-PC+blood+EPA+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-DS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool+9-HODE+blood+AA+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-DS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool-nutriCA+stool-AA+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-DS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool-nutriCA+stool+18:0/20:3-PC+blood-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-DS
CDCA+stool	Visfatin	CDCA+stool+20:3n6+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.0229	no	no	no	dn	no	up	DM-DS
CA+stool	Visfatin	CA+stool+nutriCA+stool-AA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-DS
CA+stool	Visfatin	CA+stool+16:0/20:3-PC+blood+20:2/18:0-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-DS
CA+stool	Visfatin	CA+stool+nutriCA+stool+20:2/18:0-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-DS
CA+stool	Visfatin	CA+stool+GCA+stool+DPA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-DS
CA+stool	Visfatin	CA+stool+16:0/20:3-PC+blood+20:3n6+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-DS
CA+stool	Visfatin	CA+stool+nutriCA+stool+20:3n6+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-DS
CA+stool	Visfatin	CA+stool+CDCA+stool+20:3n6+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-DS
CA+stool	Visfatin	CA+stool+16:0/20:3-PC+blood+18:0/18:1-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-DS
CA+stool	Visfatin	CA+stool+nutriCA+stool+18:0/18:1-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-DS
CA+stool	Visfatin	CA+stool+L-Tyrosine+blood-TXB2+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-DS
CA+stool	Visfatin	CA+stool+16:0/20:3-PC+blood+18:0/20:3-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-DS
CA+stool	Visfatin	CA+stool+nutriCA+stool+18:0/20:3-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-DS
CA+stool	Visfatin	CA+stool+L-Tyrosine+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-DS
CA+stool	Visfatin	CA+stool+nutriCA+stool+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-DS
HDCA+blood	Visfatin	HDCA+blood+Hypotaurine+blood+L-Glutamine+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.0229	no	no	no	dn	no	up	DM-DS
HDCA+blood	Visfatin	HDCA+blood+Hypotaurine+blood+Taurine+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.0229	no	no	no	dn	no	up	DM-DS
HDCA+blood	Visfatin	HDCA+blood+Hypotaurine+blood-Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.0229	no	no	no	dn	no	up	DM-DS
HDCA+blood	Visfatin	HDCA+blood+Hypotaurine+blood+L-Asparagine+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.0229	no	no	no	dn	no	up	DM-DS
UDCA+stool	Visfatin	UDCA+stool+16:0/20:3-PC+blood+18:0/18:1-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.0229	no	no	no	dn	no	up	DM-DS
UDCA+stool	Visfatin	UDCA+stool+16:0/20:3-PC+blood+18:0/20:3-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.0229	no	no	no	dn	no	up	DM-DS
UDCA+stool	Visfatin	UDCA+stool+L-Tyrosine+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.0229	no	no	no	dn	no	up	DM-DS
UDCA+stool	Visfatin	UDCA+stool+18:0/20:3-PI+blood-EPA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.0229	no	no	no	dn	no	up	DM-DS
UDCA+stool	Visfatin	UDCA+stool+L-Tyrosine+blood-TXB2+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.0229	no	no	no	dn	no	up	DM-DS
UDCA+stool	Visfatin	UDCA+stool+16:0/20:3-PC+blood+20:2/18:0-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.0229	no	no	no	dn	no	up	DM-DS
UDCA+stool	Visfatin	UDCA+stool+18:0/20:3-PI+blood+20:2/18:0-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.0229	no	no	no	dn	no	up	DM-DS
UDCA+stool	Visfatin	UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.0229	no	no	no	dn	no	up	DM-DS
UDCA+stool	Visfatin	UDCA+stool+16:0/20:3-PC+blood+20:3n6+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.0229	no	no	no	dn	no	up	DM-DS
UDCA+stool	Visfatin	UDCA+stool+18:0/20:3-PI+blood+20:3n6+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.0229	no	no	no	dn	no	up	DM-DS
TDCA+stool	Visfatin	TDCA+stool-d18:1-16:0-SM+blood+d18:1-20:1-SM+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.0229	no	no	no	dn	no	up	DM-DS
TDCA+stool	Visfatin	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PE+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.0229	no	no	no	dn	no	up	DM-DS
TDCA+stool	Visfatin	TDCA+stool-12-ketoDCA+blood+Ethanolamine+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.0229	no	no	no	dn	no	up	DM-DS
TDCA+stool	Visfatin	TDCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.0229	no	no	no	dn	no	up	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	Visfatin	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-PDGF-bb-Leptin-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.973	0.0229	no	no	no	dn	no	up	DM-DS
Desulfovibrio	Visfatin	Desulfovibrio+Human T-cell leukemia virus 1 infection-d18:1-18:0-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.27	0.0229	no	no	no	dn	no	up	DM-DS
Desulfovibrio	Visfatin	Desulfovibrio+Human cytomegalovirus infection-d18:1-18:0-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.27	0.0229	no	no	no	dn	no	up	DM-DS
Desulfovibrio	Visfatin	Desulfovibrio+Human immunodeficiency virus 1 infection-d18:1-18:0-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.27	0.0229	no	no	no	dn	no	up	DM-DS
Desulfovibrio	Visfatin	Desulfovibrio+Human T-cell leukemia virus 1 infection-d18:1-20:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.27	0.0229	no	no	no	dn	no	up	DM-DS
Desulfovibrio	Visfatin	Desulfovibrio+Herpes simplex virus 1 infection-d18:1-20:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.27	0.0229	no	no	no	dn	no	up	DM-DS
Desulfovibrio	Visfatin	Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.27	0.0229	no	no	no	dn	no	up	DM-DS
Desulfovibrio	Visfatin	Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.27	0.0229	no	no	no	dn	no	up	DM-DS
Desulfovibrio	Visfatin	Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.27	0.0229	no	no	no	dn	no	up	DM-DS
nutriCA+stool	Visfatin	nutriCA+stool+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.0229	no	no	no	dn	no	up	DM-DS
nutriCA+stool	Visfatin	nutriCA+stool+18:0/18:1-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.0229	no	no	no	dn	no	up	DM-DS
nutriCA+stool	Visfatin	nutriCA+stool-AA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.0229	no	no	no	dn	no	up	DM-DS
nutriCA+stool	Visfatin	nutriCA+stool+20:2/18:0-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.0229	no	no	no	dn	no	up	DM-DS
nutriCA+stool	Visfatin	nutriCA+stool+18:0/20:3-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.0229	no	no	no	dn	no	up	DM-DS
nutriCA+stool	Visfatin	nutriCA+stool+20:3n6+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.0229	no	no	no	dn	no	up	DM-DS
Bilophila	Visfatin	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-d18:1-18:0-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.528	0.0229	no	no	no	dn	no	up	DM-DS
Bilophila	Visfatin	Bilophila+Desulfovibrio+Human cytomegalovirus infection-d18:1-18:0-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.528	0.0229	no	no	no	dn	no	up	DM-DS
Bilophila	Visfatin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-d18:1-18:0-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.528	0.0229	no	no	no	dn	no	up	DM-DS
Bilophila	Visfatin	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-d18:1-20:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.528	0.0229	no	no	no	dn	no	up	DM-DS
Bilophila	Visfatin	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-d18:1-20:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.528	0.0229	no	no	no	dn	no	up	DM-DS
Bilophila	Visfatin	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.528	0.0229	no	no	no	dn	no	up	DM-DS
Bilophila	Visfatin	Bilophila+Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.528	0.0229	no	no	no	dn	no	up	DM-DS
Bilophila	Visfatin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.528	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+blood	Visfatin	GDCA+blood+PUFA/MUFA+blood+UFA%+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+blood	Visfatin	GDCA+blood+Hypotaurine+blood-Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+blood	Visfatin	GDCA+blood-IP-10+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+blood	Visfatin	GDCA+blood+PUFA/MUFA+blood-Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+blood	Visfatin	GDCA+blood+Hypotaurine+blood+L-Glutamine+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+blood	Visfatin	GDCA+blood+Hypotaurine+blood+Taurine+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+blood	Visfatin	GDCA+blood+PUFA/MUFA+blood+Taurine+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+blood	Visfatin	GDCA+blood+PUFA/MUFA+blood+PUFA%+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.0229	no	no	no	dn	no	up	DM-DS
GDCA+blood	Visfatin	GDCA+blood+Hypotaurine+blood+L-Asparagine+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.0229	no	no	no	dn	no	up	DM-DS
P-hydroxyhippuric acid+urine	Visfatin	P-hydroxyhippuric acid+urine+Eotaxin-IL-6-IP-10+Leptin-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.436	0.0229	no	no	no	dn	no	up	DM-DS
acetic acid C2+blood	Visfatin	acetic acid C2+blood+d18:1-20:1-SM+blood+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.000193	0.0229	up	dn	no	dn	no	up	DM-DS
isovaleric acid iso-C5+blood	Visfatin	isovaleric acid iso-C5+blood+n3+blood+TXB2+blood+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.117	0.0229	no	no	no	dn	no	up	DM-DS
isovaleric acid iso-C5+blood	Visfatin	isovaleric acid iso-C5+blood-L-Phenylalanine+blood+MUFA%+blood+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.117	0.0229	no	no	no	dn	no	up	DM-DS
isovaleric acid iso-C5+blood	Visfatin	isovaleric acid iso-C5+blood-L-Phenylalanine+blood+UFA%+blood+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.117	0.0229	no	no	no	dn	no	up	DM-DS
L-Phenylalanine+urine	Visfatin	L-Phenylalanine+urine-Visfatin	Direct	urine_cometabolism	DM-associated hormones	0.0908	0.0229	no	up	no	dn	no	up	DM-DS
Clostridium	Visfatin	Clostridium+Intestinal immune network for IgA production-Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	DM-DS
Clostridium	Visfatin	Clostridium+18:1/18:1-PE+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	DM-DS
Clostridium	Visfatin	Clostridium-Ethanolamine+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	DM-DS
Clostridium	Visfatin	Clostridium+20:3n6+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	DM-DS
Clostridium	Visfatin	Clostridium+18:0/20:3-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	DM-DS
Clostridium	Visfatin	Clostridium+18:0/18:1-PE+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	DM-DS
Clostridium	Visfatin	Clostridium+20:2/18:0-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	DM-DS
T-¦Á-MCA+stool	Visfatin	T-¦Á-MCA+stool+TUDCA+stool-14:0/18:2-PC+blood-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.0229	no	no	no	dn	no	up	DM-DS
12-ketoDCA+blood	Visfatin	12-ketoDCA+blood-18:1/18:1-PE+blood-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.0229	no	no	no	dn	no	up	DM-DS
12-ketoDCA+blood	Visfatin	12-ketoDCA+blood-18:0/18:1-PE+blood-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.0229	no	no	no	dn	no	up	DM-DS
12-ketoDCA+blood	Visfatin	12-ketoDCA+blood+Ethanolamine+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.0229	no	no	no	dn	no	up	DM-DS
Butyricicoccus	Visfatin	"Butyricicoccus+12,13-EPOME+blood-TMAO+blood+Visfatin"	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	DM-DS
Butyricicoccus	Visfatin	"Butyricicoccus+12,13-EPOME+blood+18:1/18:1-PE+blood-Visfatin"	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	DM-DS
Butyricicoccus	Visfatin	Butyricicoccus-18:2/20:4-PC+blood+EPA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	DM-DS
Butyricicoccus	Visfatin	Butyricicoccus+TUDCA+stool-14:0/18:2-PC+blood-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	DM-DS
Butyricicoccus	Visfatin	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood-Visfatin"	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	DM-DS
Butyricicoccus	Visfatin	"Butyricicoccus+12,13-EPOME+blood+18:0/18:1-PE+blood-Visfatin"	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	DM-DS
Butyricicoccus	Visfatin	"Butyricicoccus+12,13-EPOME+blood-d18:1-20:1-SM+blood+Visfatin"	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	DM-DS
Butyricicoccus	Visfatin	Butyricicoccus-DL-Indole-3-lactic acid+urine-Leptin-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	DM-DS
Butyricicoccus	Visfatin	"Butyricicoccus+12,13-EPOME+blood-18:1-LPC+blood+Visfatin"	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	DM-DS
3-Hydroxy-L-kynurenine+urine	Visfatin	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.401	0.0229	no	no	no	dn	no	up	DM-DS
3-Hydroxy-L-kynurenine+urine	Visfatin	3-Hydroxy-L-kynurenine+urine+L-Phenylalanine+urine-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.401	0.0229	no	no	no	dn	no	up	DM-DS
Blautia	PAI-1	Blautia+Longevity regulating pathway - multiple species-PAI-1	Indirect	Genus	DM-associated hormones	1.36E-05	5.10E-05	up	dn	dn	up	up	up	DM-DS
Parabacteroides	PAI-1	Parabacteroides+20:0/20:5-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	4.19E-05	5.10E-05	no	up	up	up	up	up	DM-DS
Dorea	PAI-1	Dorea+Glycolysis / Gluconeogenesis-PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.00362	5.10E-05	up	no	dn	up	up	up	DM-DS
Dorea	PAI-1	Dorea+Carbon metabolism-Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.00362	5.10E-05	up	no	dn	up	up	up	DM-DS
Dorea	PAI-1	Dorea+Carbon metabolism+Longevity regulating pathway - multiple species-PAI-1	Indirect	Genus	DM-associated hormones	0.00362	5.10E-05	up	no	dn	up	up	up	DM-DS
Dorea	PAI-1	Dorea+L-Tyrosine+blood+Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.00362	5.10E-05	up	no	dn	up	up	up	DM-DS
Dorea	PAI-1	Dorea+Carbon metabolism-Necroptosis+PAI-1	Indirect	Genus	DM-associated hormones	0.00362	5.10E-05	up	no	dn	up	up	up	DM-DS
Faecalibacterium	PAI-1	Faecalibacterium+PAI-1	Direct	Genus	DM-associated hormones	0.0039	5.10E-05	no	dn	dn	up	up	up	DM-DS
TUDCA+blood	PAI-1	TUDCA+blood+L-Phenylalanine+urine-Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0282	5.10E-05	no	no	dn	up	up	up	DM-DS
Bacteroides	PAI-1	Bacteroides+16:1/16:1-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.000267	5.10E-05	dn	dn	up	up	up	up	DM-DS
Bacteroides	PAI-1	Bacteroides+20:3/18:0-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.000267	5.10E-05	dn	dn	up	up	up	up	DM-DS
Bacteroides	PAI-1	Bacteroides+Longevity regulating pathway - multiple species-PAI-1	Indirect	Genus	DM-associated hormones	0.000267	5.10E-05	dn	dn	up	up	up	up	DM-DS
Propionic acid+stool	PAI-1	Propionic acid+stool-L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.0436	5.10E-05	dn	no	up	up	up	up	DM-DS
Propionic acid+stool	PAI-1	Propionic acid+stool-16:0/16:0-PC+blood+18:0/22:6-PA+blood-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.0436	5.10E-05	dn	no	up	up	up	up	DM-DS
[Ruminococcus]	PAI-1	[Ruminococcus]+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.0679	5.10E-05	no	no	dn	up	up	up	DM-DS
GUDCA+blood	PAI-1	GUDCA+blood+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0766	5.10E-05	no	no	dn	up	up	up	DM-DS
UDCA+blood	PAI-1	UDCA+blood+L-Phenylalanine+urine-Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0939	5.10E-05	no	no	dn	up	up	up	DM-DS
Acetic acid+stool	PAI-1	Acetic acid+stool-18:0/18:0-PS+blood+Leptin-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.0656	5.10E-05	dn	no	no	up	up	up	DM-DS
Acetic acid+stool	PAI-1	Acetic acid+stool-16:0/18:0-PS+blood+18:0/22:6-PA+blood-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.0656	5.10E-05	dn	no	no	up	up	up	DM-DS
Acetic acid+stool	PAI-1	Acetic acid+stool-18:0/18:0-PS+blood+18:0/22:6-PA+blood-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.0656	5.10E-05	dn	no	no	up	up	up	DM-DS
Acetic acid+stool	PAI-1	Acetic acid+stool-14:0+blood-20:3/18:0-PC+blood-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.0656	5.10E-05	dn	no	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes-16:0/16:0-PC+blood+18:0/22:6-PA+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes+nutriCA+stool+18:0/22:6-PA+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes+nutriCA+stool-18:2-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes+nutriCA+stool+Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes-18:2/16:0-PC+blood-Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes-Betaine+blood-Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes-Salivary secretion-Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes+nutriCA+stool-PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes-Influenza A-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes+MAPK signaling pathway+Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes+Platinum drug resistance+Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes-Rap1 signaling pathway-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes-Ferroptosis-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes-Ferroptosis+Necroptosis+PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes+Colorectal cancer-16:1/16:1-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes+Signaling pathways regulating pluripotency of stem cells-16:1/16:1-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes+Gastric cancer-16:1/16:1-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes+MAPK signaling pathway-Mitophagy - animal+PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes+MAPK signaling pathway-Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes+Platinum drug resistance-Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes-Ferroptosis+Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes-Vibrio cholerae infection+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes+MAPK signaling pathway-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes+Platinum drug resistance-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes-Ferroptosis+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	"Alistipes+T cell receptor signaling pathway-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	"Alistipes+MAPK signaling pathway-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	"Alistipes-Ferroptosis+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes+MAPK signaling pathway-Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Alistipes	PAI-1	Alistipes-Ferroptosis+Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-DS
Butyricimonas	PAI-1	Butyricimonas+Cholinergic synapse-Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.17	5.10E-05	no	no	no	up	up	up	DM-DS
Butyricimonas	PAI-1	Butyricimonas+Cholinergic synapse-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.17	5.10E-05	no	no	no	up	up	up	DM-DS
Collinsella	PAI-1	Collinsella-GnRH signaling pathway+Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.128	5.10E-05	no	no	no	up	up	up	DM-DS
Collinsella	PAI-1	Collinsella-Endocrine and other factor-regulated calcium reabsorption+Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.128	5.10E-05	no	no	no	up	up	up	DM-DS
Collinsella	PAI-1	"Collinsella-GnRH signaling pathway+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.128	5.10E-05	no	no	no	up	up	up	DM-DS
Collinsella	PAI-1	"Collinsella-Renin secretion+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.128	5.10E-05	no	no	no	up	up	up	DM-DS
Collinsella	PAI-1	"Collinsella-Inflammatory mediator regulation of TRP channels+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.128	5.10E-05	no	no	no	up	up	up	DM-DS
Collinsella	PAI-1	Collinsella-DL-Indole-3-lactic acid+urine-Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.128	5.10E-05	no	no	no	up	up	up	DM-DS
Collinsella	PAI-1	Collinsella-GnRH signaling pathway+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.128	5.10E-05	no	no	no	up	up	up	DM-DS
Collinsella	PAI-1	Collinsella-Renin secretion+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.128	5.10E-05	no	no	no	up	up	up	DM-DS
Collinsella	PAI-1	Collinsella-Endocrine and other factor-regulated calcium reabsorption+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.128	5.10E-05	no	no	no	up	up	up	DM-DS
Collinsella	PAI-1	Collinsella-Inflammatory mediator regulation of TRP channels+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.128	5.10E-05	no	no	no	up	up	up	DM-DS
Collinsella	PAI-1	Collinsella-GnRH signaling pathway-18:0/22:6-PA+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.128	5.10E-05	no	no	no	up	up	up	DM-DS
Collinsella	PAI-1	Collinsella+Roseburia+Faecalibacterium+PAI-1	Indirect	Genus	DM-associated hormones	0.128	5.10E-05	no	no	no	up	up	up	DM-DS
5-Hydroxytryptamine+urine	PAI-1	5-Hydroxytryptamine+urine+L-Phenylalanine+urine-Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.171	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina-Glucagon signaling pathway+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Osteoclast differentiation-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina-Inflammatory mediator regulation of TRP channels+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina-Dopaminergic synapse+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina-Amphetamine addiction+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina-GnRH signaling pathway+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina-Aldosterone synthesis and secretion+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Fc epsilon RI signaling pathway-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Prolactin signaling pathway-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina-Glucagon signaling pathway+Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Osteoclast differentiation-Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina-Dopaminergic synapse+Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina-GnRH signaling pathway+Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina-Aldosterone synthesis and secretion+Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Hepatitis C+Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	"Sarcina-Glucagon signaling pathway+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	"Sarcina+Osteoclast differentiation-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	"Sarcina-Inflammatory mediator regulation of TRP channels+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	"Sarcina-Dopaminergic synapse+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	"Sarcina+Cellular senescence-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	"Sarcina+Apoptosis-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	"Sarcina+NF-kappa B signaling pathway-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	"Sarcina-Circadian entrainment+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	"Sarcina+RIG-I-like receptor signaling pathway-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	"Sarcina-GnRH signaling pathway+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	"Sarcina-Aldosterone synthesis and secretion+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	"Sarcina+Fc epsilon RI signaling pathway-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	"Sarcina+Prolactin signaling pathway-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Viral carcinogenesis-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Acute myeloid leukemia-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Cellular senescence-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Human papillomavirus infection-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Apoptosis-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Neurotrophin signaling pathway-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Chronic myeloid leukemia-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Toll-like receptor signaling pathway-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Fc epsilon RI signaling pathway-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Prostate cancer-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+C-type lectin receptor signaling pathway-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Prolactin signaling pathway-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+TNF signaling pathway-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+B cell receptor signaling pathway-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+IP-10+Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Neurotrophin signaling pathway+PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Chronic myeloid leukemia+PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Prostate cancer+PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+C-type lectin receptor signaling pathway+PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+Prolactin signaling pathway+PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina+TNF signaling pathway+PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Sarcina	PAI-1	Sarcina-GnRH signaling pathway-18:0/22:6-PA+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
Methanosphaera	PAI-1	Methanosphaera-Roseburia+Faecalibacterium+PAI-1	Indirect	Genus	DM-associated hormones	0.0703	5.10E-05	no	no	no	up	up	up	DM-DS
iso-DCA+stool	PAI-1	iso-DCA+stool+Propionic acid+stool-L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-DS
iso-DCA+stool	PAI-1	iso-DCA+stool+Propionic acid+stool-16:0/16:0-PC+blood+18:0/22:6-PA+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-DS
LCA+stool	PAI-1	LCA+stool-UDCA+stool+L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.314	5.10E-05	no	no	no	up	up	up	DM-DS
Akkermansia	PAI-1	Akkermansia-Cholinergic synapse-Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	DM-DS
Akkermansia	PAI-1	Akkermansia-Cholinergic synapse-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	DM-DS
Akkermansia	PAI-1	Akkermansia-Cytokine-cytokine receptor interaction+16:1/16:1-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	DM-DS
Akkermansia	PAI-1	Akkermansia-Cytokine-cytokine receptor interaction-Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	DM-DS
Akkermansia	PAI-1	Akkermansia-Cytokine-cytokine receptor interaction+Longevity regulating pathway - multiple species-PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	DM-DS
Akkermansia	PAI-1	Akkermansia-Cytokine-cytokine receptor interaction-Mitophagy - animal+PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	DM-DS
Akkermansia	PAI-1	"Akkermansia-Cytokine-cytokine receptor interaction-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	DM-DS
Bifidobacterium	PAI-1	Bifidobacterium-16:0+blood-Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-DS
Bifidobacterium	PAI-1	Bifidobacterium+L-Tyrosine+blood+Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-DS
Bifidobacterium	PAI-1	Bifidobacterium+HIF-1 signaling pathway+Mitophagy - animal+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-DS
Bifidobacterium	PAI-1	Bifidobacterium-FoxO signaling pathway-Mitophagy - animal+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-DS
Bifidobacterium	PAI-1	"Bifidobacterium+HIF-1 signaling pathway+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-DS
Bifidobacterium	PAI-1	"Bifidobacterium-FoxO signaling pathway-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-DS
Bifidobacterium	PAI-1	Bifidobacterium+Vibrio cholerae infection+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-DS
Bifidobacterium	PAI-1	Bifidobacterium+Gastric acid secretion+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-DS
Bifidobacterium	PAI-1	Bifidobacterium-Autophagy - animal-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-DS
Bifidobacterium	PAI-1	Bifidobacterium+HIF-1 signaling pathway+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-DS
Bifidobacterium	PAI-1	Bifidobacterium-FoxO signaling pathway-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-DS
Bifidobacterium	PAI-1	Bifidobacterium+Leukocyte transendothelial migration-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-DS
Bifidobacterium	PAI-1	Bifidobacterium-FoxO signaling pathway-Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-DS
Bifidobacterium	PAI-1	Bifidobacterium-18:0/20:4-PI+blood+18:0/22:6-PA+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-DS
Bifidobacterium	PAI-1	Bifidobacterium-Transcriptional misregulation in cancer+PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-DS
Bifidobacterium	PAI-1	Bifidobacterium+Glycolysis / Gluconeogenesis-PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-DS
3-Hydroxytyramine hydrochloride+urine	PAI-1	3-Hydroxytyramine hydrochloride+urine+5-Hydroxytryptamine+urine+L-Phenylalanine+urine-Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.288	5.10E-05	no	no	no	up	up	up	DM-DS
3-Hydroxytyramine hydrochloride+urine	PAI-1	3-Hydroxytyramine hydrochloride+urine-Hippuric acid+urine-IL-6-IP-10+Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.288	5.10E-05	no	no	no	up	up	up	DM-DS
Phenylacetyl L-GlutaMine+urine	PAI-1	Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.0909	5.10E-05	up	no	no	up	up	up	DM-DS
Ruminococcus	PAI-1	Ruminococcus-PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.335	5.10E-05	no	no	no	up	up	up	DM-DS
Ruminococcus	PAI-1	Ruminococcus+Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.335	5.10E-05	no	no	no	up	up	up	DM-DS
GCDCA+blood	PAI-1	GCDCA+blood+GUDCA+blood+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.31	5.10E-05	no	no	no	up	up	up	DM-DS
GCDCA+blood	PAI-1	GCDCA+blood-Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.31	5.10E-05	no	no	no	up	up	up	DM-DS
GCDCA+blood	PAI-1	GCDCA+blood+L-Tyrosine+blood+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.31	5.10E-05	no	no	no	up	up	up	DM-DS
ACA+blood	PAI-1	ACA+blood-decanoic acid C10+blood+L-Phenylalanine+blood+L-Tyrosine+blood+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.338	5.10E-05	no	no	no	up	up	up	DM-DS
ACA+blood	PAI-1	ACA+blood-decanoic acid C10+blood+L-Isoleucine+blood+L-Tyrosine+blood+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.338	5.10E-05	no	no	no	up	up	up	DM-DS
ACA+blood	PAI-1	ACA+blood+EPA+blood-n6/n3+blood+PUFA/MUFA+blood-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.338	5.10E-05	no	no	no	up	up	up	DM-DS
ACA+blood	PAI-1	ACA+blood-decanoic acid C10+blood+n6/n3+blood+PUFA/MUFA+blood-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.338	5.10E-05	no	no	no	up	up	up	DM-DS
ACA+blood	PAI-1	ACA+blood+EPA+blood-n6/n3+blood+PUFA%+blood-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.338	5.10E-05	no	no	no	up	up	up	DM-DS
ACA+blood	PAI-1	ACA+blood-decanoic acid C10+blood+n6/n3+blood+PUFA%+blood-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.338	5.10E-05	no	no	no	up	up	up	DM-DS
DCA+stool	PAI-1	DCA+stool-GCA+stool+DPA+blood+PDGF-bb+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.195	5.10E-05	no	no	no	up	up	up	DM-DS
DCA+stool	PAI-1	DCA+stool-L-Tryptophan+stool+8-HETE+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.195	5.10E-05	no	no	no	up	up	up	DM-DS
DCA+stool	PAI-1	DCA+stool+HDCA+stool-16:0/20:4-PI+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.195	5.10E-05	no	no	no	up	up	up	DM-DS
DCA+stool	PAI-1	DCA+stool-GCA+stool+DPA+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.195	5.10E-05	no	no	no	up	up	up	DM-DS
DCA+stool	PAI-1	DCA+stool-L-Tryptophan+stool+9-HODE+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.195	5.10E-05	no	no	no	up	up	up	DM-DS
DCA+stool	PAI-1	DCA+stool-GCA+stool+L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.195	5.10E-05	no	no	no	up	up	up	DM-DS
DCA+stool	PAI-1	DCA+stool+HDCA+stool-16:0/20:4-PI+blood-18:2-LPC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.195	5.10E-05	no	no	no	up	up	up	DM-DS
DCA+stool	PAI-1	DCA+stool+iso-LCA+stool-TCA+stool-20:0/20:5-PC+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.195	5.10E-05	no	no	no	up	up	up	DM-DS
2-hydroxyhippuric acid+urine	PAI-1	2-hydroxyhippuric acid+urine-3-Hydroxy-L-kynurenine+urine+DL-Indole-3-lactic acid+urine-Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.215	5.10E-05	no	no	no	up	up	up	DM-DS
Hippuric acid+urine	PAI-1	Hippuric acid+urine-IL-6-IP-10+Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.361	5.10E-05	no	no	no	up	up	up	DM-DS
Butyric acid+stool	PAI-1	Butyric acid+stool-16:0/20:5-PC+blood+18:0/22:6-PA+blood-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.102	5.10E-05	dn	no	no	up	up	up	DM-DS
4-hydroxybenzoic acid+stool	PAI-1	4-hydroxybenzoic acid+stool-iso-LCA+stool-TCA+stool-20:0/20:5-PC+blood-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.0536	5.10E-05	no	dn	no	up	up	up	DM-DS
4-hydroxybenzoic acid+stool	PAI-1	4-hydroxybenzoic acid+stool+L-Tryptophan+stool+8-HETE+blood-Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.0536	5.10E-05	no	dn	no	up	up	up	DM-DS
4-hydroxybenzoic acid+stool	PAI-1	4-hydroxybenzoic acid+stool+L-Tryptophan+stool+9-HODE+blood-Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.0536	5.10E-05	no	dn	no	up	up	up	DM-DS
Turicibacter	PAI-1	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-20:0/20:5-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.269	5.10E-05	no	no	no	up	up	up	DM-DS
Turicibacter	PAI-1	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-20:0/20:5-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.269	5.10E-05	no	no	no	up	up	up	DM-DS
Turicibacter	PAI-1	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-20:0/20:5-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.269	5.10E-05	no	no	no	up	up	up	DM-DS
Turicibacter	PAI-1	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-20:0/20:5-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.269	5.10E-05	no	no	no	up	up	up	DM-DS
Turicibacter	PAI-1	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.269	5.10E-05	no	no	no	up	up	up	DM-DS
Turicibacter	PAI-1	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.269	5.10E-05	no	no	no	up	up	up	DM-DS
Turicibacter	PAI-1	Turicibacter+Desulfovibrio+Antigen processing and presentation+Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.269	5.10E-05	no	no	no	up	up	up	DM-DS
Turicibacter	PAI-1	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.269	5.10E-05	no	no	no	up	up	up	DM-DS
GCA+blood	PAI-1	GCA+blood-Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.16	5.10E-05	no	no	no	up	up	up	DM-DS
ACA+stool	PAI-1	ACA+stool-Kynurenic acid+stool-nutriCA+stool-PDGF-bb+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.417	5.10E-05	no	no	no	up	up	up	DM-DS
ACA+stool	PAI-1	ACA+stool-Kynurenic acid+stool-nutriCA+stool-18:2-LPC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.417	5.10E-05	no	no	no	up	up	up	DM-DS
ACA+stool	PAI-1	ACA+stool-Kynurenic acid+stool-nutriCA+stool+18:0/22:6-PA+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.417	5.10E-05	no	no	no	up	up	up	DM-DS
ACA+stool	PAI-1	ACA+stool-Kynurenic acid+stool-nutriCA+stool+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.417	5.10E-05	no	no	no	up	up	up	DM-DS
ACA+stool	PAI-1	ACA+stool-L-Tryptophan+stool+8-HETE+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.417	5.10E-05	no	no	no	up	up	up	DM-DS
ACA+stool	PAI-1	ACA+stool-L-Phenylalanine+stool+8-HETE+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.417	5.10E-05	no	no	no	up	up	up	DM-DS
ACA+stool	PAI-1	ACA+stool-L-Tryptophan+stool+9-HODE+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.417	5.10E-05	no	no	no	up	up	up	DM-DS
ACA+stool	PAI-1	ACA+stool-L-Phenylalanine+stool+9-HODE+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.417	5.10E-05	no	no	no	up	up	up	DM-DS
CDCA+blood	PAI-1	CDCA+blood-Ethanolamine+blood+PDGF-bb+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.506	5.10E-05	no	no	no	up	up	up	DM-DS
CDCA+blood	PAI-1	CDCA+blood-Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.506	5.10E-05	no	no	no	up	up	up	DM-DS
CDCA+blood	PAI-1	CDCA+blood+GUDCA+blood+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.506	5.10E-05	no	no	no	up	up	up	DM-DS
CDCA+blood	PAI-1	CDCA+blood-PUFA%+blood-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.506	5.10E-05	no	no	no	up	up	up	DM-DS
capric acid C6+blood	PAI-1	capric acid C6+blood-HCA+blood-Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.433	5.10E-05	no	no	no	up	up	up	DM-DS
Prevotella	PAI-1	Prevotella-20:3/18:0-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.287	5.10E-05	no	no	no	up	up	up	DM-DS
TCA+blood	PAI-1	TCA+blood+TUDCA+blood+L-Phenylalanine+urine-Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.339	5.10E-05	no	no	no	up	up	up	DM-DS
iso-DCA+blood	PAI-1	iso-DCA+blood-IP-10+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.38	5.10E-05	no	no	no	up	up	up	DM-DS
HCA+stool	PAI-1	HCA+stool-HDCA+stool-16:0/20:4-PI+blood-18:2-LPC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-DS
HCA+stool	PAI-1	HCA+stool-HDCA+stool-16:0/20:4-PI+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-DS
Roseburia	PAI-1	Roseburia+Faecalibacterium+PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+stool	PAI-1	12-ketoDCA+stool-GCA+stool+DPA+blood+PDGF-bb+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.505	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+stool	PAI-1	12-ketoDCA+stool+iso-LCA+stool-TCA+stool-20:0/20:5-PC+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.505	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+stool	PAI-1	12-ketoDCA+stool+GCA+blood-Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.505	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+stool	PAI-1	12-ketoDCA+stool-GCA+stool+DPA+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.505	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+stool	PAI-1	12-ketoDCA+stool-GCA+stool+L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.505	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+stool	PAI-1	12-ketoDCA+stool+HDCA+stool-16:0/20:4-PI+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.505	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+stool	PAI-1	12-ketoDCA+stool-MUFA%+blood+PUFA%+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.505	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+stool	PAI-1	12-ketoDCA+stool+HDCA+stool-16:0/20:4-PI+blood-18:2-LPC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.505	5.10E-05	no	no	no	up	up	up	DM-DS
GLCA+blood	PAI-1	GLCA+blood+TDCA+blood-IP-10+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.319	5.10E-05	no	no	no	up	up	up	DM-DS
L-Tryptophan+stool	PAI-1	L-Tryptophan+stool+9-HODE+blood-Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.557	5.10E-05	no	no	no	up	up	up	DM-DS
L-Tryptophan+stool	PAI-1	L-Tryptophan+stool+8-HETE+blood-Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.557	5.10E-05	no	no	no	up	up	up	DM-DS
CA+blood	PAI-1	CA+blood+GUDCA+blood+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	DM-DS
CA+blood	PAI-1	CA+blood-Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	DM-DS
GUDCA+stool	PAI-1	GUDCA+stool+TUDCA+stool+9-HODE+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0085	5.10E-05	no	dn	no	up	up	up	DM-DS
GUDCA+stool	PAI-1	GUDCA+stool+12-HEPE+blood-L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0085	5.10E-05	no	dn	no	up	up	up	DM-DS
GUDCA+stool	PAI-1	GUDCA+stool+12-HEPE+blood+16:0/20:5-PC+blood+18:0/22:6-PA+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0085	5.10E-05	no	dn	no	up	up	up	DM-DS
GUDCA+stool	PAI-1	GUDCA+stool+TUDCA+stool-d18:1-14:0-SM+blood-PDGF-bb+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0085	5.10E-05	no	dn	no	up	up	up	DM-DS
L-Phenylalanine+stool	PAI-1	L-Phenylalanine+stool+8-HETE+blood-Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.398	5.10E-05	no	no	no	up	up	up	DM-DS
L-Phenylalanine+stool	PAI-1	L-Phenylalanine+stool+9-HODE+blood-Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.398	5.10E-05	no	no	no	up	up	up	DM-DS
butyric acid C4+blood	PAI-1	butyric acid C4+blood+L-Ornithine+blood+PDGF-bb+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.407	5.10E-05	no	no	no	up	up	up	DM-DS
GCA+stool	PAI-1	GCA+stool+DPA+blood+PDGF-bb+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0809	5.10E-05	no	no	no	up	up	up	DM-DS
GCA+stool	PAI-1	GCA+stool+L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0809	5.10E-05	no	no	no	up	up	up	DM-DS
GCA+stool	PAI-1	GCA+stool+DPA+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0809	5.10E-05	no	no	no	up	up	up	DM-DS
Coprococcus	PAI-1	Coprococcus+Roseburia+Faecalibacterium+PAI-1	Indirect	Genus	DM-associated hormones	0.612	5.10E-05	no	no	no	up	up	up	DM-DS
Coprococcus	PAI-1	Coprococcus+16:0/16:0-PC+blood+18:0/22:6-PA+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.612	5.10E-05	no	no	no	up	up	up	DM-DS
Coprococcus	PAI-1	Coprococcus+L-Tyrosine+blood+Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.612	5.10E-05	no	no	no	up	up	up	DM-DS
Indole-3-Acetic acid+urine	PAI-1	Indole-3-Acetic acid+urine+Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.657	5.10E-05	no	no	no	up	up	up	DM-DS
Oscillospira	PAI-1	Oscillospira-PAI-1	Direct	Genus	DM-associated hormones	0.62	5.10E-05	no	no	no	up	up	up	DM-DS
HCA+blood	PAI-1	HCA+blood-Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.544	5.10E-05	no	no	no	up	up	up	DM-DS
iso-LCA+stool	PAI-1	iso-LCA+stool-TCA+stool-20:0/20:5-PC+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.72	5.10E-05	no	no	no	up	up	up	DM-DS
DCA+blood	PAI-1	DCA+blood+nutriCA+blood-Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.122	5.10E-05	no	no	no	up	up	up	DM-DS
DCA+blood	PAI-1	DCA+blood+L-Histidine+blood+PUFA%+blood-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.122	5.10E-05	no	no	no	up	up	up	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-d18:1-14:0-SM+blood-PDGF-bb+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool+9-HODE+blood-Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	PAI-1	"3-(3,4-dihydroxyphenyl)propionic acid+urine+DL-Indole-3-lactic acid+urine-Leptin-PAI-1"	Indirect	urine_cometabolism	DM-associated hormones	0.0125	5.10E-05	up	up	no	up	up	up	DM-DS
nutriCA+blood	PAI-1	nutriCA+blood-Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.726	5.10E-05	no	no	no	up	up	up	DM-DS
4-hydroxybenzoic acid+urine	PAI-1	4-hydroxybenzoic acid+urine+Homovanillic acid+urine-IP-10+Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.52	5.10E-05	no	no	no	up	up	up	DM-DS
4-hydroxybenzoic acid+urine	PAI-1	4-hydroxybenzoic acid+urine+Indole-3-Acetic acid+urine+Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.52	5.10E-05	no	no	no	up	up	up	DM-DS
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool-nutriCA+stool+18:0/22:6-PA+blood-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	DM-DS
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool-nutriCA+stool-18:2-LPC+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	DM-DS
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool-nutriCA+stool-PDGF-bb+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	DM-DS
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool-nutriCA+stool+Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	DM-DS
TCA+stool	PAI-1	TCA+stool-20:0/20:5-PC+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.458	5.10E-05	no	no	no	up	up	up	DM-DS
HDCA+stool	PAI-1	HDCA+stool-16:0/20:4-PI+blood-18:2-LPC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.176	5.10E-05	no	no	no	up	up	up	DM-DS
HDCA+stool	PAI-1	HDCA+stool-16:0/20:4-PI+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.176	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-p53 signaling pathway+Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-Chronic myeloid leukemia-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-Prostate cancer-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-Progesterone-mediated oocyte maturation+Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-Platinum drug resistance+Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-Cytosolic DNA-sensing pathway-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira+Rap1 signaling pathway-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-Spliceosome+Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira+Leukocyte transendothelial migration-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-TNF signaling pathway-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira+Vibrio cholerae infection+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-Progesterone-mediated oocyte maturation-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira+Gastric acid secretion+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-Platinum drug resistance-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira+Renin secretion+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-Autophagy - animal-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira+Vascular smooth muscle contraction+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-FoxO signaling pathway-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-JAK-STAT signaling pathway-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-NOD-like receptor signaling pathway-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-Chronic myeloid leukemia+PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-Prostate cancer+PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira+Glycolysis / Gluconeogenesis-PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-Cytosolic DNA-sensing pathway+PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-Transcriptional misregulation in cancer+PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-TNF signaling pathway+PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira+Carbon metabolism-Necroptosis+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-Progesterone-mediated oocyte maturation-Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-Platinum drug resistance-Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-Cytosolic DNA-sensing pathway+Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-FoxO signaling pathway-Mitophagy - animal+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	"Lachnospira-T cell receptor signaling pathway-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	"Lachnospira+Renin secretion+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	"Lachnospira-RIG-I-like receptor signaling pathway-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	"Lachnospira+Circadian entrainment+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	"Lachnospira+Vascular smooth muscle contraction+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	"Lachnospira-FoxO signaling pathway-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	"Lachnospira-JAK-STAT signaling pathway-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	"Lachnospira-NOD-like receptor signaling pathway-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	"Lachnospira-NF-kappa B signaling pathway-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira+TCA+stool-20:0/20:5-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira+Carbon metabolism-Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira+Vascular smooth muscle contraction+Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-FoxO signaling pathway-Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira+Carbon metabolism+Longevity regulating pathway - multiple species-PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Lachnospira	PAI-1	Lachnospira-Signaling pathways regulating pluripotency of stem cells-16:1/16:1-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-DS
Fusobacterium	PAI-1	Fusobacterium-18:0/18:0-PC+blood+18:0/22:6-PA+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.628	5.10E-05	no	no	no	up	up	up	DM-DS
Fusobacterium	PAI-1	Fusobacterium-18:0/18:1-PC+blood+18:0/22:6-PA+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.628	5.10E-05	no	no	no	up	up	up	DM-DS
Fusobacterium	PAI-1	Fusobacterium-16:0/18:1-PC+blood+18:0/22:6-PA+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.628	5.10E-05	no	no	no	up	up	up	DM-DS
Fusobacterium	PAI-1	Fusobacterium-18:0/18:0-PC+blood-18:2-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.628	5.10E-05	no	no	no	up	up	up	DM-DS
Fusobacterium	PAI-1	Fusobacterium-18:0/18:1-PC+blood-18:2-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.628	5.10E-05	no	no	no	up	up	up	DM-DS
Fusobacterium	PAI-1	Fusobacterium-18:0/18:0-PC+blood-PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.628	5.10E-05	no	no	no	up	up	up	DM-DS
Fusobacterium	PAI-1	Fusobacterium-18:0/18:1-PC+blood-PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.628	5.10E-05	no	no	no	up	up	up	DM-DS
Fusobacterium	PAI-1	Fusobacterium-18:0/18:0-PC+blood+Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.628	5.10E-05	no	no	no	up	up	up	DM-DS
Fusobacterium	PAI-1	Fusobacterium-18:0/18:1-PC+blood+Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.628	5.10E-05	no	no	no	up	up	up	DM-DS
Fusobacterium	PAI-1	Fusobacterium-GUDCA+blood+Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.628	5.10E-05	no	no	no	up	up	up	DM-DS
Fusobacterium	PAI-1	Fusobacterium-16:0/18:1-PC+blood+20:3/18:0-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.628	5.10E-05	no	no	no	up	up	up	DM-DS
Fusobacterium	PAI-1	Fusobacterium-18:0/16:0-PC+blood+20:3/18:0-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.628	5.10E-05	no	no	no	up	up	up	DM-DS
GCDCA+stool	PAI-1	GCDCA+stool+16:0/18:1-PC+blood+20:3/18:0-PC+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0471	5.10E-05	no	dn	no	up	up	up	DM-DS
GCDCA+stool	PAI-1	GCDCA+stool+L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0471	5.10E-05	no	dn	no	up	up	up	DM-DS
GCDCA+stool	PAI-1	GCDCA+stool+20:3n6+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0471	5.10E-05	no	dn	no	up	up	up	DM-DS
GCDCA+stool	PAI-1	GCDCA+stool+16:0/18:1-PC+blood+18:0/22:6-PA+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0471	5.10E-05	no	dn	no	up	up	up	DM-DS
5-Hydroxytryptamine+stool	PAI-1	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/22:6-PA+blood-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.00862	5.10E-05	dn	dn	no	up	up	up	DM-DS
5-Hydroxytryptamine+stool	PAI-1	5-Hydroxytryptamine+stool-nutriCA+stool-18:2-LPC+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.00862	5.10E-05	dn	dn	no	up	up	up	DM-DS
5-Hydroxytryptamine+stool	PAI-1	5-Hydroxytryptamine+stool-nutriCA+stool+Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.00862	5.10E-05	dn	dn	no	up	up	up	DM-DS
5-Hydroxytryptamine+stool	PAI-1	5-Hydroxytryptamine+stool-nutriCA+stool-PDGF-bb+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.00862	5.10E-05	dn	dn	no	up	up	up	DM-DS
Odoribacter	PAI-1	Odoribacter-Necroptosis+PAI-1	Indirect	Genus	DM-associated hormones	0.798	5.10E-05	no	no	no	up	up	up	DM-DS
Odoribacter	PAI-1	Odoribacter+Longevity regulating pathway - multiple species-PAI-1	Indirect	Genus	DM-associated hormones	0.798	5.10E-05	no	no	no	up	up	up	DM-DS
Actinomyces	PAI-1	Actinomyces+Coprococcus+Roseburia+Faecalibacterium+PAI-1	Indirect	Genus	DM-associated hormones	0.621	5.10E-05	no	no	no	up	up	up	DM-DS
Actinomyces	PAI-1	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:0/22:6-PA+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.621	5.10E-05	no	no	no	up	up	up	DM-DS
Actinomyces	PAI-1	Actinomyces+Coprococcus+L-Tyrosine+blood+Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.621	5.10E-05	no	no	no	up	up	up	DM-DS
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool-nutriCA+stool-PDGF-bb+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	DM-DS
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool-nutriCA+stool+Leptin-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	DM-DS
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool-nutriCA+stool+18:0/22:6-PA+blood-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	DM-DS
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool-nutriCA+stool-18:2-LPC+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	DM-DS
2-hydroxyphenylacetic acid+urine	PAI-1	2-hydroxyphenylacetic acid+urine-L-Phenylalanine+urine-Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.763	5.10E-05	no	no	no	up	up	up	DM-DS
2-hydroxyphenylacetic acid+urine	PAI-1	"2-hydroxyphenylacetic acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine+DL-Indole-3-lactic acid+urine-Leptin-PAI-1"	Indirect	urine_cometabolism	DM-associated hormones	0.763	5.10E-05	no	no	no	up	up	up	DM-DS
2-hydroxyphenylacetic acid+urine	PAI-1	2-hydroxyphenylacetic acid+urine-3-Hydroxy-L-kynurenine+urine+DL-Indole-3-lactic acid+urine-Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.763	5.10E-05	no	no	no	up	up	up	DM-DS
2-hydroxyphenylacetic acid+urine	PAI-1	2-hydroxyphenylacetic acid+urine+Homovanillic acid+urine-IP-10+Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.763	5.10E-05	no	no	no	up	up	up	DM-DS
Kynurenic acid+stool	PAI-1	Kynurenic acid+stool-nutriCA+stool-18:2-LPC+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.037	5.10E-05	dn	dn	no	up	up	up	DM-DS
Kynurenic acid+stool	PAI-1	Kynurenic acid+stool-nutriCA+stool-PDGF-bb+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.037	5.10E-05	dn	dn	no	up	up	up	DM-DS
Kynurenic acid+stool	PAI-1	Kynurenic acid+stool-nutriCA+stool+18:0/22:6-PA+blood-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.037	5.10E-05	dn	dn	no	up	up	up	DM-DS
Kynurenic acid+stool	PAI-1	Kynurenic acid+stool-nutriCA+stool+Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.037	5.10E-05	dn	dn	no	up	up	up	DM-DS
Caproic acid+stool	PAI-1	Caproic acid+stool-TCA+stool-20:0/20:5-PC+blood-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.882	5.10E-05	no	no	no	up	up	up	DM-DS
Eggerthella	PAI-1	Eggerthella-Yersinia infection-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	DM-DS
Eggerthella	PAI-1	Eggerthella+Phosphatidylinositol signaling system+Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	DM-DS
Eggerthella	PAI-1	Eggerthella-Influenza A-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	DM-DS
Eggerthella	PAI-1	Eggerthella+nutriCA+stool+18:0/22:6-PA+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	DM-DS
Eggerthella	PAI-1	Eggerthella+nutriCA+stool-18:2-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	DM-DS
Eggerthella	PAI-1	Eggerthella+Phosphatidylinositol signaling system-Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	DM-DS
Eggerthella	PAI-1	Eggerthella+Phosphatidylinositol signaling system-Necroptosis+PAI-1	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	DM-DS
Eggerthella	PAI-1	Eggerthella+AMPK signaling pathway+Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	DM-DS
Eggerthella	PAI-1	"Eggerthella+AMPK signaling pathway+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	DM-DS
Eggerthella	PAI-1	Eggerthella+AMPK signaling pathway+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	DM-DS
Eggerthella	PAI-1	Eggerthella+nutriCA+stool-PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	DM-DS
Eggerthella	PAI-1	Eggerthella+nutriCA+stool+Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	DM-DS
Anaerotruncus	PAI-1	Anaerotruncus-Ruminococcus-PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.904	5.10E-05	no	no	no	up	up	up	DM-DS
Anaerotruncus	PAI-1	Anaerotruncus-Ruminococcus+Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.904	5.10E-05	no	no	no	up	up	up	DM-DS
Anaerostipes	PAI-1	"Anaerostipes-Neutrophil extracellular trap formation-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.568	5.10E-05	no	no	no	up	up	up	DM-DS
Anaerostipes	PAI-1	"Anaerostipes+RNA degradation+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.568	5.10E-05	no	no	no	up	up	up	DM-DS
Anaerostipes	PAI-1	Anaerostipes+Spliceosome+Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.568	5.10E-05	no	no	no	up	up	up	DM-DS
Anaerostipes	PAI-1	Anaerostipes-Rap1 signaling pathway-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.568	5.10E-05	no	no	no	up	up	up	DM-DS
Anaerostipes	PAI-1	Anaerostipes+RNA degradation+Mitophagy - animal+PAI-1	Indirect	Genus	DM-associated hormones	0.568	5.10E-05	no	no	no	up	up	up	DM-DS
TUDCA+stool	PAI-1	TUDCA+stool+9-HODE+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.241	5.10E-05	no	no	no	up	up	up	DM-DS
TUDCA+stool	PAI-1	TUDCA+stool-d18:1-14:0-SM+blood-PDGF-bb+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.241	5.10E-05	no	no	no	up	up	up	DM-DS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+Phenylacetic acid+stool-18:0/16:0-PC+blood+20:3/18:0-PC+blood-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-DS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/18:1-PC+blood+20:3/18:0-PC+blood-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-DS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+Phenylacetic acid+stool-14:0+blood-20:3/18:0-PC+blood-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-DS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/18:1-PC+blood+18:0/22:6-PA+blood-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-DS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+L-Phenylalanine+stool+9-HODE+blood-Leptin-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-DS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+Phenylacetic acid+stool-20:3n6+blood+Leptin-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-DS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+L-Phenylalanine+stool+8-HETE+blood-Leptin-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-DS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+Phenylacetic acid+stool-L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-DS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool-UDCA+stool+L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-DS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+Phenylacetic acid+stool-GUDCA+blood+Leptin-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-Peroxisome+Longevity regulating pathway - multiple species-PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-Glioma-20:3/18:0-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-cGMP-PKG signaling pathway-Mitophagy - animal+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-Biosynthesis of amino acids-Mitophagy - animal+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-Nicotinate and nicotinamide metabolism-Mitophagy - animal+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella+RNA degradation+Mitophagy - animal+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-Arginine and proline metabolism-Mitophagy - animal+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-cGMP-PKG signaling pathway-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-Fc epsilon RI signaling pathway-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-Epithelial cell signaling in Helicobacter pylori infection-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-IL-17 signaling pathway-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella+Ribosome biogenesis in eukaryotes+Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella+Cell cycle+Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-Fc gamma R-mediated phagocytosis-Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-Peroxisome-Mineral absorption+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-Fc gamma R-mediated phagocytosis-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella+Inflammatory mediator regulation of TRP channels+Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-Nicotinate and nicotinamide metabolism-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-Fc epsilon RI signaling pathway-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-Peroxisome-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-Arginine and proline metabolism-Shigellosis+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	"Paraprevotella+Wnt signaling pathway+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	"Paraprevotella-cGMP-PKG signaling pathway-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	"Paraprevotella+Protein processing in endoplasmic reticulum+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	"Paraprevotella-Fc gamma R-mediated phagocytosis-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	"Paraprevotella-Biosynthesis of amino acids-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	"Paraprevotella+Inflammatory mediator regulation of TRP channels+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	"Paraprevotella-PPAR signaling pathway-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	"Paraprevotella-Nicotinate and nicotinamide metabolism-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	"Paraprevotella-Fc epsilon RI signaling pathway-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	"Paraprevotella-Peroxisome-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	"Paraprevotella-Olfactory transduction-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	"Paraprevotella+RNA degradation+Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	"Paraprevotella-Arginine and proline metabolism-Parathyroid hormone synthesis, secretion and action+PAI-1"	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-Adipocytokine signaling pathway+Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella-Adipocytokine signaling pathway+PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Paraprevotella	PAI-1	Paraprevotella+IP-10+Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-DS
Homovanillic acid+urine	PAI-1	Homovanillic acid+urine-IP-10+Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.45	5.10E-05	no	no	no	up	up	up	DM-DS
TDCA+blood	PAI-1	TDCA+blood-IP-10+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.155	5.10E-05	no	up	no	up	up	up	DM-DS
DL-Indole-3-lactic acid+urine	PAI-1	DL-Indole-3-lactic acid+urine-Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.00552	5.10E-05	up	up	no	up	up	up	DM-DS
Phenaceturic acid+urine	PAI-1	Phenaceturic acid+urine+Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.737	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool-L-Tyrosine+stool-nutriCA+stool-PDGF-bb+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool-Isobutyric acid+stool-nutriCA+stool-PDGF-bb+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool+CDCA+stool+nutriCA+stool-PDGF-bb+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool+GDCA+stool+16:0/18:1-PC+blood+20:3/18:0-PC+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool+CDCA+stool+16:0/18:1-PC+blood+20:3/18:0-PC+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool-L-Tyrosine+stool-nutriCA+stool-18:2-LPC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool-Isobutyric acid+stool-nutriCA+stool-18:2-LPC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool+CDCA+stool+nutriCA+stool-18:2-LPC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool-L-Tyrosine+stool-nutriCA+stool+18:0/22:6-PA+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool-Isobutyric acid+stool-nutriCA+stool+18:0/22:6-PA+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool+CDCA+stool+nutriCA+stool+18:0/22:6-PA+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool+GDCA+stool+16:0/18:1-PC+blood+18:0/22:6-PA+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool+CDCA+stool+16:0/18:1-PC+blood+18:0/22:6-PA+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool-L-Tyrosine+stool-nutriCA+stool+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool-Isobutyric acid+stool-nutriCA+stool+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool+CDCA+stool+nutriCA+stool+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool+CDCA+stool+20:3n6+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool-L-Phenylalanine+stool+8-HETE+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool-L-Tryptophan+stool+8-HETE+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool-L-Tyrosine+stool+9-HODE+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool-L-Phenylalanine+stool+9-HODE+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool-L-Tryptophan+stool+9-HODE+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool+GDCA+stool+IP-10+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool+CDCA+stool+IP-10+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool+GDCA+stool+L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool+CDCA+stool+L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	DM-DS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool-14:0+blood-20:3/18:0-PC+blood-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-DS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool-16:0/18:1-PC+blood+20:3/18:0-PC+blood-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-DS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool-18:0/16:0-PC+blood+20:3/18:0-PC+blood-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-DS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool-16:0/18:1-PC+blood+18:0/22:6-PA+blood-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-DS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool-GUDCA+blood+Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-DS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool-L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-DS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool-20:3n6+blood+Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-DS
Gemmiger	PAI-1	Gemmiger+Central carbon metabolism in cancer+Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.595	5.10E-05	no	no	no	up	up	up	DM-DS
Gemmiger	PAI-1	Gemmiger+Signaling pathways regulating pluripotency of stem cells-16:1/16:1-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.595	5.10E-05	no	no	no	up	up	up	DM-DS
Gemmiger	PAI-1	Gemmiger+Colorectal cancer-16:1/16:1-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.595	5.10E-05	no	no	no	up	up	up	DM-DS
Gemmiger	PAI-1	Gemmiger+Gastric cancer-16:1/16:1-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.595	5.10E-05	no	no	no	up	up	up	DM-DS
GDCA+stool	PAI-1	GDCA+stool+16:0/18:1-PC+blood+20:3/18:0-PC+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	DM-DS
GDCA+stool	PAI-1	GDCA+stool+16:0/18:1-PC+blood+18:0/22:6-PA+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	DM-DS
GDCA+stool	PAI-1	GDCA+stool+L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	DM-DS
GDCA+stool	PAI-1	GDCA+stool+IP-10+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	DM-DS
Methanobrevibacter	PAI-1	Methanobrevibacter+d18:1-14:0-SM+blood-PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.629	5.10E-05	no	no	no	up	up	up	DM-DS
L-Tyrosine+stool	PAI-1	L-Tyrosine+stool-nutriCA+stool-18:2-LPC+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.44	5.10E-05	no	no	no	up	up	up	DM-DS
L-Tyrosine+stool	PAI-1	L-Tyrosine+stool-nutriCA+stool-PDGF-bb+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.44	5.10E-05	no	no	no	up	up	up	DM-DS
L-Tyrosine+stool	PAI-1	L-Tyrosine+stool+9-HODE+blood-Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.44	5.10E-05	no	no	no	up	up	up	DM-DS
L-Tyrosine+stool	PAI-1	L-Tyrosine+stool-nutriCA+stool+Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.44	5.10E-05	no	no	no	up	up	up	DM-DS
L-Tyrosine+stool	PAI-1	L-Tyrosine+stool-nutriCA+stool+18:0/22:6-PA+blood-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.44	5.10E-05	no	no	no	up	up	up	DM-DS
CDCA+stool	PAI-1	CDCA+stool+16:0/18:1-PC+blood+18:0/22:6-PA+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.663	5.10E-05	no	no	no	up	up	up	DM-DS
CDCA+stool	PAI-1	CDCA+stool+nutriCA+stool+18:0/22:6-PA+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.663	5.10E-05	no	no	no	up	up	up	DM-DS
CDCA+stool	PAI-1	CDCA+stool+16:0/18:1-PC+blood+20:3/18:0-PC+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.663	5.10E-05	no	no	no	up	up	up	DM-DS
CDCA+stool	PAI-1	CDCA+stool+nutriCA+stool-18:2-LPC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.663	5.10E-05	no	no	no	up	up	up	DM-DS
CDCA+stool	PAI-1	CDCA+stool+nutriCA+stool+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.663	5.10E-05	no	no	no	up	up	up	DM-DS
CDCA+stool	PAI-1	CDCA+stool+L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.663	5.10E-05	no	no	no	up	up	up	DM-DS
CDCA+stool	PAI-1	CDCA+stool+IP-10+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.663	5.10E-05	no	no	no	up	up	up	DM-DS
CDCA+stool	PAI-1	CDCA+stool+20:3n6+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.663	5.10E-05	no	no	no	up	up	up	DM-DS
CDCA+stool	PAI-1	CDCA+stool+nutriCA+stool-PDGF-bb+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.663	5.10E-05	no	no	no	up	up	up	DM-DS
CA+stool	PAI-1	CA+stool+nutriCA+stool-18:2-LPC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.827	5.10E-05	no	no	no	up	up	up	DM-DS
CA+stool	PAI-1	CA+stool+nutriCA+stool+18:0/22:6-PA+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.827	5.10E-05	no	no	no	up	up	up	DM-DS
CA+stool	PAI-1	CA+stool+nutriCA+stool-PDGF-bb+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.827	5.10E-05	no	no	no	up	up	up	DM-DS
CA+stool	PAI-1	CA+stool+L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.827	5.10E-05	no	no	no	up	up	up	DM-DS
CA+stool	PAI-1	CA+stool+nutriCA+stool+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.827	5.10E-05	no	no	no	up	up	up	DM-DS
HDCA+blood	PAI-1	HDCA+blood+Hypotaurine+blood-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.483	5.10E-05	no	no	no	up	up	up	DM-DS
UDCA+stool	PAI-1	UDCA+stool+L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.266	5.10E-05	no	no	no	up	up	up	DM-DS
TDCA+stool	PAI-1	TDCA+stool-12-ketoDCA+blood-18:0/22:6-PI+blood-18:2-LPC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.963	5.10E-05	no	no	no	up	up	up	DM-DS
TDCA+stool	PAI-1	TDCA+stool-12-ketoDCA+blood-18:1/22:6-PE+blood-18:2-LPC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.963	5.10E-05	no	no	no	up	up	up	DM-DS
TDCA+stool	PAI-1	TDCA+stool-12-ketoDCA+blood-18:0/22:6-PI+blood+20:0/20:5-PC+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.963	5.10E-05	no	no	no	up	up	up	DM-DS
TDCA+stool	PAI-1	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood+18:0/22:6-PA+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.963	5.10E-05	no	no	no	up	up	up	DM-DS
TDCA+stool	PAI-1	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood+18:0/22:6-PA+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.963	5.10E-05	no	no	no	up	up	up	DM-DS
TDCA+stool	PAI-1	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.963	5.10E-05	no	no	no	up	up	up	DM-DS
TDCA+stool	PAI-1	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PE+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.963	5.10E-05	no	no	no	up	up	up	DM-DS
TDCA+stool	PAI-1	TDCA+stool-HDCA+blood+Hypotaurine+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.963	5.10E-05	no	no	no	up	up	up	DM-DS
TDCA+stool	PAI-1	TDCA+stool-12-ketoDCA+blood+Ethanolamine+blood+PDGF-bb+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.963	5.10E-05	no	no	no	up	up	up	DM-DS
TDCA+stool	PAI-1	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PE+blood-20:3/18:0-PC+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.963	5.10E-05	no	no	no	up	up	up	DM-DS
TDCA+stool	PAI-1	TDCA+stool-12-ketoDCA+blood-14:0+blood-20:3/18:0-PC+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.963	5.10E-05	no	no	no	up	up	up	DM-DS
TDCA+stool	PAI-1	TDCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood-20:3/18:0-PC+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.963	5.10E-05	no	no	no	up	up	up	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	PAI-1	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-PDGF-bb+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.973	5.10E-05	no	no	no	up	up	up	DM-DS
Desulfovibrio	PAI-1	Desulfovibrio+Human T-cell leukemia virus 1 infection+Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.27	5.10E-05	no	no	no	up	up	up	DM-DS
Desulfovibrio	PAI-1	Desulfovibrio+Human cytomegalovirus infection+Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.27	5.10E-05	no	no	no	up	up	up	DM-DS
Desulfovibrio	PAI-1	Desulfovibrio+Antigen processing and presentation+Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.27	5.10E-05	no	no	no	up	up	up	DM-DS
Desulfovibrio	PAI-1	Desulfovibrio+Human T-cell leukemia virus 1 infection-20:0/20:5-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.27	5.10E-05	no	no	no	up	up	up	DM-DS
Desulfovibrio	PAI-1	Desulfovibrio+Human cytomegalovirus infection-20:0/20:5-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.27	5.10E-05	no	no	no	up	up	up	DM-DS
Desulfovibrio	PAI-1	Desulfovibrio+Human immunodeficiency virus 1 infection-20:0/20:5-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.27	5.10E-05	no	no	no	up	up	up	DM-DS
Desulfovibrio	PAI-1	Desulfovibrio+Herpes simplex virus 1 infection-20:0/20:5-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.27	5.10E-05	no	no	no	up	up	up	DM-DS
Desulfovibrio	PAI-1	Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.27	5.10E-05	no	no	no	up	up	up	DM-DS
nutriCA+stool	PAI-1	nutriCA+stool+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.481	5.10E-05	no	no	no	up	up	up	DM-DS
nutriCA+stool	PAI-1	nutriCA+stool+18:0/22:6-PA+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.481	5.10E-05	no	no	no	up	up	up	DM-DS
nutriCA+stool	PAI-1	nutriCA+stool-18:2-LPC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.481	5.10E-05	no	no	no	up	up	up	DM-DS
nutriCA+stool	PAI-1	nutriCA+stool-PDGF-bb+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.481	5.10E-05	no	no	no	up	up	up	DM-DS
Bilophila	PAI-1	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.528	5.10E-05	no	no	no	up	up	up	DM-DS
Bilophila	PAI-1	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.528	5.10E-05	no	no	no	up	up	up	DM-DS
Bilophila	PAI-1	Bilophila+Desulfovibrio+Antigen processing and presentation+Kaposi sarcoma-associated herpesvirus infection+PAI-1	Indirect	Genus	DM-associated hormones	0.528	5.10E-05	no	no	no	up	up	up	DM-DS
Bilophila	PAI-1	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-20:0/20:5-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.528	5.10E-05	no	no	no	up	up	up	DM-DS
Bilophila	PAI-1	Bilophila+Desulfovibrio+Human cytomegalovirus infection-20:0/20:5-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.528	5.10E-05	no	no	no	up	up	up	DM-DS
Bilophila	PAI-1	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-20:0/20:5-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.528	5.10E-05	no	no	no	up	up	up	DM-DS
Bilophila	PAI-1	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-20:0/20:5-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.528	5.10E-05	no	no	no	up	up	up	DM-DS
Bilophila	PAI-1	Bilophila+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-PAI-1	Indirect	Genus	DM-associated hormones	0.528	5.10E-05	no	no	no	up	up	up	DM-DS
GDCA+blood	PAI-1	GDCA+blood+Hypotaurine+blood-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.632	5.10E-05	no	no	no	up	up	up	DM-DS
GDCA+blood	PAI-1	GDCA+blood-IP-10+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.632	5.10E-05	no	no	no	up	up	up	DM-DS
GDCA+blood	PAI-1	GDCA+blood+PUFA/MUFA+blood-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.632	5.10E-05	no	no	no	up	up	up	DM-DS
P-hydroxyhippuric acid+urine	PAI-1	P-hydroxyhippuric acid+urine+Eotaxin-IL-6-IP-10+Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.436	5.10E-05	no	no	no	up	up	up	DM-DS
P-hydroxyhippuric acid+urine	PAI-1	P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13-PDGF-bb+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.436	5.10E-05	no	no	no	up	up	up	DM-DS
acetic acid C2+blood	PAI-1	acetic acid C2+blood+d18:1-20:1-SM+blood-GUDCA+blood+Leptin-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.000193	5.10E-05	up	dn	no	up	up	up	DM-DS
acetic acid C2+blood	PAI-1	acetic acid C2+blood+d18:1-20:1-SM+blood-L-Tyrosine+blood+Leptin-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.000193	5.10E-05	up	dn	no	up	up	up	DM-DS
isovaleric acid iso-C5+blood	PAI-1	isovaleric acid iso-C5+blood-L-Phenylalanine+blood+L-Tyrosine+blood+Leptin-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.117	5.10E-05	no	no	no	up	up	up	DM-DS
L-Phenylalanine+urine	PAI-1	L-Phenylalanine+urine-Phenylacetyl L-GlutaMine+urine-Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.0908	5.10E-05	no	up	no	up	up	up	DM-DS
Clostridium	PAI-1	Clostridium-18:2-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.925	5.10E-05	no	no	no	up	up	up	DM-DS
T-¦Á-MCA+stool	PAI-1	T-¦Á-MCA+stool+TUDCA+stool-d18:1-14:0-SM+blood-PDGF-bb+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.48	5.10E-05	no	no	no	up	up	up	DM-DS
T-¦Á-MCA+stool	PAI-1	T-¦Á-MCA+stool-UDCA+stool+L-Tyrosine+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.48	5.10E-05	no	no	no	up	up	up	DM-DS
T-¦Á-MCA+stool	PAI-1	T-¦Á-MCA+stool+TUDCA+stool+9-HODE+blood-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.48	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood+Ethanolamine+blood+PDGF-bb+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:0/22:6-PI+blood+20:0/20:5-PC+blood-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:1/18:0-PE+blood-20:3/18:0-PC+blood-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-14:0+blood-20:3/18:0-PC+blood-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:0/18:1-PE+blood-20:3/18:0-PC+blood-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:0/18:1-PE+blood+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:0/18:0-PS+blood+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:0/18:0-PS+blood+18:0/22:6-PA+blood-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-16:0/18:0-PS+blood+18:0/22:6-PA+blood-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:1/22:6-PE+blood-18:2-LPC+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	DM-DS
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:0/22:6-PI+blood-18:2-LPC+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	DM-DS
Butyricicoccus	PAI-1	Butyricicoccus-DL-Indole-3-lactic acid+urine-Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.852	5.10E-05	no	no	no	up	up	up	DM-DS
3-Hydroxy-L-kynurenine+urine	PAI-1	3-Hydroxy-L-kynurenine+urine+DL-Indole-3-lactic acid+urine-Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.401	5.10E-05	no	no	no	up	up	up	DM-DS
Blautia	MCP-1(MCAF)	Blautia+Dorea-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	DM-DS
Parabacteroides	MCP-1(MCAF)	Parabacteroides-16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	4.19E-05	0.0633	no	up	up	dn	no	up	DM-DS
Dorea	MCP-1(MCAF)	Dorea-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.00362	0.0633	up	no	dn	dn	no	up	DM-DS
Faecalibacterium	MCP-1(MCAF)	Faecalibacterium-Phenylacetic acid+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0039	0.0633	no	dn	dn	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Transcriptional misregulation in cancer-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+RNA transport+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+Oocyte meiosis+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Prolactin signaling pathway-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+Apelin signaling pathway+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Phospholipase D signaling pathway-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Amoebiasis-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Chagas disease-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Acute myeloid leukemia-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+Glycolysis / Gluconeogenesis+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+Long-term potentiation+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Prolactin signaling pathway-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Relaxin signaling pathway-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+Oocyte meiosis+Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-cAMP signaling pathway-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Prolactin signaling pathway-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Amoebiasis-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Chagas disease-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Chronic myeloid leukemia-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Acute myeloid leukemia-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+Longevity regulating pathway - multiple species+Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+Long-term potentiation+Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Long-term depression-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Pathways in cancer-16:0/20:4-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+Parabacteroides-16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Amoebiasis+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+16:1/16:1-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+16:0/22:6-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+20:3/18:0-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+18:0/20:4-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+Apelin signaling pathway-IL-17 signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Phospholipase D signaling pathway+IL-17 signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Pathways in cancer+L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+16:0/20:5-PC+blood-L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+Glycolysis / Gluconeogenesis-p53 signaling pathway+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Transcriptional misregulation in cancer-Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Pathways in cancer-Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Chronic myeloid leukemia-Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Choline metabolism in cancer-Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-MicroRNAs in cancer-Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	"Bacteroides-Growth hormone synthesis, secretion and action-Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+Glycolysis / Gluconeogenesis+Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-16:1/18:2-PG+blood+18:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+Long-term potentiation-18:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Long-term depression+18:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+Glycolysis / Gluconeogenesis+Leukocyte transendothelial migration-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+Glycolysis / Gluconeogenesis+Platelet activation-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+RNA transport-Neutrophil extracellular trap formation-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+Apelin signaling pathway-Neutrophil extracellular trap formation-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides-Phospholipase D signaling pathway+Neutrophil extracellular trap formation-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+RNA transport+Measles+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+Legionellosis+Measles+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Bacteroides	MCP-1(MCAF)	Bacteroides+Leishmaniasis+Measles+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-DS
Propionic acid+stool	MCP-1(MCAF)	Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.0436	0.0633	dn	no	up	dn	no	up	DM-DS
[Ruminococcus]	MCP-1(MCAF)	[Ruminococcus]-Progesterone-mediated oocyte maturation+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0679	0.0633	no	no	dn	dn	no	up	DM-DS
[Ruminococcus]	MCP-1(MCAF)	[Ruminococcus]+16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0679	0.0633	no	no	dn	dn	no	up	DM-DS
GUDCA+blood	MCP-1(MCAF)	GUDCA+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0633	no	no	dn	dn	no	up	DM-DS
UDCA+blood	MCP-1(MCAF)	UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.0939	0.0633	no	no	dn	dn	no	up	DM-DS
Acetic acid+stool	MCP-1(MCAF)	Acetic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.0656	0.0633	dn	no	no	dn	no	up	DM-DS
Alistipes	MCP-1(MCAF)	Alistipes-Platelet activation-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0114	0.0633	no	up	no	dn	no	up	DM-DS
Alistipes	MCP-1(MCAF)	Alistipes-Oxytocin signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0114	0.0633	no	up	no	dn	no	up	DM-DS
Alistipes	MCP-1(MCAF)	Alistipes-Rap1 signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0114	0.0633	no	up	no	dn	no	up	DM-DS
Butyricimonas	MCP-1(MCAF)	Butyricimonas-L-Asparagine+blood+L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	DM-DS
Butyricimonas	MCP-1(MCAF)	Butyricimonas-iso-DCA+blood+L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	DM-DS
Butyricimonas	MCP-1(MCAF)	Butyricimonas-Butyric acid+stool+L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	DM-DS
Butyricimonas	MCP-1(MCAF)	Butyricimonas-Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	DM-DS
Collinsella	MCP-1(MCAF)	Collinsella+Roseburia+16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-DS
Collinsella	MCP-1(MCAF)	Collinsella-Renin secretion+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-DS
Collinsella	MCP-1(MCAF)	Collinsella-Inflammatory mediator regulation of TRP channels+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-DS
Collinsella	MCP-1(MCAF)	Collinsella-Endocrine and other factor-regulated calcium reabsorption+P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-DS
Collinsella	MCP-1(MCAF)	Collinsella-GnRH signaling pathway-Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-DS
Collinsella	MCP-1(MCAF)	Collinsella-Renin secretion-Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-DS
Collinsella	MCP-1(MCAF)	Collinsella-Endocrine and other factor-regulated calcium reabsorption-Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-DS
Collinsella	MCP-1(MCAF)	Collinsella-Inflammatory mediator regulation of TRP channels-Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-DS
Collinsella	MCP-1(MCAF)	Collinsella-GnRH signaling pathway+HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-DS
Collinsella	MCP-1(MCAF)	Collinsella-Endocrine and other factor-regulated calcium reabsorption+HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Osteoclast differentiation+Neutrophil extracellular trap formation-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Cellular senescence+Neutrophil extracellular trap formation-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Apoptosis+Neutrophil extracellular trap formation-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Osteoclast differentiation+IL-17 signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Cellular senescence+IL-17 signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Apoptosis+IL-17 signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+NF-kappa B signaling pathway+IL-17 signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Toll-like receptor signaling pathway+IL-17 signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+RIG-I-like receptor signaling pathway+IL-17 signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+C-type lectin receptor signaling pathway+IL-17 signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Dopaminergic synapse-Measles+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Hepatitis C+Measles+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Circadian entrainment-Measles+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Th17 cell differentiation+Measles+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Apoptosis+18:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Viral carcinogenesis-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Glucagon signaling pathway+HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Osteoclast differentiation-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Dopaminergic synapse+HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Cellular senescence-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Human papillomavirus infection-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Apoptosis-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Amphetamine addiction+HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-GnRH signaling pathway+HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Aldosterone synthesis and secretion+HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Fc epsilon RI signaling pathway-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Prolactin signaling pathway-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Glucagon signaling pathway+P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Aldosterone synthesis and secretion+P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Viral carcinogenesis-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Acute myeloid leukemia-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Cellular senescence-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Human papillomavirus infection-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Apoptosis-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Neurotrophin signaling pathway-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Chronic myeloid leukemia-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Toll-like receptor signaling pathway-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Fc epsilon RI signaling pathway-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Prostate cancer-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+C-type lectin receptor signaling pathway-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Prolactin signaling pathway-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+TNF signaling pathway-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+B cell receptor signaling pathway-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+NF-kappa B signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Insulin resistance-Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Circadian entrainment+Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Chronic myeloid leukemia-Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+RIG-I-like receptor signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Prostate cancer-Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+NF-kappa B signaling pathway-Oxytocin signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Circadian entrainment+Oxytocin signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+RIG-I-like receptor signaling pathway-Oxytocin signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+TNF signaling pathway-Oxytocin signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+NF-kappa B signaling pathway-Platelet activation-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Viral carcinogenesis+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Glucagon signaling pathway-Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Osteoclast differentiation+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Inflammatory mediator regulation of TRP channels-Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Cellular senescence+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Human papillomavirus infection+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Apoptosis+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Amphetamine addiction-Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Toll-like receptor signaling pathway+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-GnRH signaling pathway-Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Aldosterone synthesis and secretion-Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Fc epsilon RI signaling pathway+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+C-type lectin receptor signaling pathway+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+B cell receptor signaling pathway+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Glucagon signaling pathway+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Osteoclast differentiation-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Inflammatory mediator regulation of TRP channels+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Acute myeloid leukemia-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Apoptosis-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+NF-kappa B signaling pathway-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Amphetamine addiction+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Toll-like receptor signaling pathway-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+RIG-I-like receptor signaling pathway-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina-Aldosterone synthesis and secretion+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Fc epsilon RI signaling pathway-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+C-type lectin receptor signaling pathway-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+Prolactin signaling pathway-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+B cell receptor signaling pathway-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Sarcina	MCP-1(MCAF)	Sarcina+FGF basic+IL-17A+IL-4+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
Methanosphaera	MCP-1(MCAF)	Methanosphaera-Roseburia+16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0703	0.0633	no	no	no	dn	no	up	DM-DS
iso-DCA+stool	MCP-1(MCAF)	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.155	0.0633	no	no	no	dn	no	up	DM-DS
LCA+stool	MCP-1(MCAF)	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.314	0.0633	no	no	no	dn	no	up	DM-DS
Akkermansia	MCP-1(MCAF)	Akkermansia+P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.23	0.0633	no	no	no	dn	no	up	DM-DS
Bifidobacterium	MCP-1(MCAF)	Bifidobacterium+Leukocyte transendothelial migration-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.105	0.0633	no	dn	no	dn	no	up	DM-DS
Ruminococcus	MCP-1(MCAF)	"Ruminococcus-18:2n6c+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-DS
Ruminococcus	MCP-1(MCAF)	Ruminococcus-Alcoholism+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-DS
Ruminococcus	MCP-1(MCAF)	Ruminococcus-Alcoholism-Measles+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-DS
Ruminococcus	MCP-1(MCAF)	Ruminococcus-Serotonergic synapse-Measles+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-DS
Ruminococcus	MCP-1(MCAF)	Ruminococcus-20:4-LPC+blood+L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-DS
Ruminococcus	MCP-1(MCAF)	Ruminococcus-EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-DS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-DS
Ruminococcus	MCP-1(MCAF)	Ruminococcus-18:3n3+blood+L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-DS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+18:0/18:0-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-DS
GCDCA+blood	MCP-1(MCAF)	GCDCA+blood+GUDCA+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.31	0.0633	no	no	no	dn	no	up	DM-DS
GCDCA+blood	MCP-1(MCAF)	GCDCA+blood+HCA+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.31	0.0633	no	no	no	dn	no	up	DM-DS
ACA+blood	MCP-1(MCAF)	ACA+blood+EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.338	0.0633	no	no	no	dn	no	up	DM-DS
DCA+stool	MCP-1(MCAF)	DCA+stool+HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.195	0.0633	no	no	no	dn	no	up	DM-DS
Butyric acid+stool	MCP-1(MCAF)	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.102	0.0633	dn	no	no	dn	no	up	DM-DS
Butyric acid+stool	MCP-1(MCAF)	Butyric acid+stool+L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.102	0.0633	dn	no	no	dn	no	up	DM-DS
4-hydroxybenzoic acid+stool	MCP-1(MCAF)	4-hydroxybenzoic acid+stool-DCA+stool+HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.0633	no	dn	no	dn	no	up	DM-DS
Turicibacter	MCP-1(MCAF)	Turicibacter+Desulfovibrio+Antigen processing and presentation+Leukocyte transendothelial migration-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.269	0.0633	no	no	no	dn	no	up	DM-DS
Turicibacter	MCP-1(MCAF)	Turicibacter+Desulfovibrio+Antigen processing and presentation-Progesterone-mediated oocyte maturation+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.269	0.0633	no	no	no	dn	no	up	DM-DS
Turicibacter	MCP-1(MCAF)	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.269	0.0633	no	no	no	dn	no	up	DM-DS
Turicibacter	MCP-1(MCAF)	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.269	0.0633	no	no	no	dn	no	up	DM-DS
Turicibacter	MCP-1(MCAF)	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.269	0.0633	no	no	no	dn	no	up	DM-DS
Turicibacter	MCP-1(MCAF)	Turicibacter+Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.269	0.0633	no	no	no	dn	no	up	DM-DS
Turicibacter	MCP-1(MCAF)	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.269	0.0633	no	no	no	dn	no	up	DM-DS
Turicibacter	MCP-1(MCAF)	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.269	0.0633	no	no	no	dn	no	up	DM-DS
Turicibacter	MCP-1(MCAF)	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.269	0.0633	no	no	no	dn	no	up	DM-DS
Turicibacter	MCP-1(MCAF)	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.269	0.0633	no	no	no	dn	no	up	DM-DS
Turicibacter	MCP-1(MCAF)	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.269	0.0633	no	no	no	dn	no	up	DM-DS
Turicibacter	MCP-1(MCAF)	Turicibacter+Desulfovibrio+Antigen processing and presentation-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.269	0.0633	no	no	no	dn	no	up	DM-DS
Turicibacter	MCP-1(MCAF)	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.269	0.0633	no	no	no	dn	no	up	DM-DS
GCA+blood	MCP-1(MCAF)	GCA+blood+HCA+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.16	0.0633	no	no	no	dn	no	up	DM-DS
ACA+stool	MCP-1(MCAF)	ACA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.417	0.0633	no	no	no	dn	no	up	DM-DS
CDCA+blood	MCP-1(MCAF)	CDCA+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.506	0.0633	no	no	no	dn	no	up	DM-DS
capric acid C6+blood	MCP-1(MCAF)	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.433	0.0633	no	no	no	dn	no	up	DM-DS
Prevotella	MCP-1(MCAF)	Prevotella-Measles+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-DS
iso-DCA+blood	MCP-1(MCAF)	iso-DCA+blood+L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.38	0.0633	no	no	no	dn	no	up	DM-DS
HCA+stool	MCP-1(MCAF)	HCA+stool-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.155	0.0633	no	no	no	dn	no	up	DM-DS
Roseburia	MCP-1(MCAF)	Roseburia+16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.495	0.0633	no	no	no	dn	no	up	DM-DS
12-ketoDCA+stool	MCP-1(MCAF)	12-ketoDCA+stool+HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.505	0.0633	no	no	no	dn	no	up	DM-DS
GLCA+blood	MCP-1(MCAF)	GLCA+blood-SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.319	0.0633	no	no	no	dn	no	up	DM-DS
L-Tryptophan+stool	MCP-1(MCAF)	L-Tryptophan+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0633	no	no	no	dn	no	up	DM-DS
CA+blood	MCP-1(MCAF)	CA+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.606	0.0633	no	no	no	dn	no	up	DM-DS
GUDCA+stool	MCP-1(MCAF)	GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0085	0.0633	no	dn	no	dn	no	up	DM-DS
L-Phenylalanine+stool	MCP-1(MCAF)	L-Phenylalanine+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool-GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool-HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool-Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool+GCDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool+GDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool+DPA+blood-nutriCA+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool+GCDCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool-Isovaleric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool-Isobutyric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool+GCDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool+UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool+GDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool-iso-LCA+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool+GCDCA+stool+16:0/16:1-PC+blood+16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool-12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool+GCDCA+stool+16:1/18:2-PG+blood+18:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	GCA+stool+GCDCA+stool+16:0/18:2-PC+blood-16:0/20:4-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
GCA+stool	MCP-1(MCAF)	"GCA+stool+GDCA+stool+L-Lysine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+MCP-1(MCAF)"	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-DS
Coprococcus	MCP-1(MCAF)	Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	DM-DS
Coprococcus	MCP-1(MCAF)	Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	DM-DS
Coprococcus	MCP-1(MCAF)	Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	DM-DS
Oscillospira	MCP-1(MCAF)	Oscillospira+Progesterone-mediated oocyte maturation+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	DM-DS
Oscillospira	MCP-1(MCAF)	Oscillospira-Rap1 signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	DM-DS
Oscillospira	MCP-1(MCAF)	Oscillospira+Spliceosome+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	DM-DS
Oscillospira	MCP-1(MCAF)	Oscillospira-Platelet activation-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	DM-DS
HCA+blood	MCP-1(MCAF)	HCA+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.544	0.0633	no	no	no	dn	no	up	DM-DS
iso-LCA+stool	MCP-1(MCAF)	iso-LCA+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.72	0.0633	no	no	no	dn	no	up	DM-DS
DCA+blood	MCP-1(MCAF)	DCA+blood+nutriCA+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.122	0.0633	no	no	no	dn	no	up	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	MCP-1(MCAF)	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+MCP-1(MCAF)"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.0633	up	up	no	dn	no	up	DM-DS
nutriCA+blood	MCP-1(MCAF)	nutriCA+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.726	0.0633	no	no	no	dn	no	up	DM-DS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-DS
TCA+stool	MCP-1(MCAF)	TCA+stool+16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.458	0.0633	no	no	no	dn	no	up	DM-DS
HDCA+stool	MCP-1(MCAF)	HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.176	0.0633	no	no	no	dn	no	up	DM-DS
Lachnospira	MCP-1(MCAF)	Lachnospira-p53 signaling pathway+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.279	0.0633	no	no	no	dn	no	up	DM-DS
Lachnospira	MCP-1(MCAF)	Lachnospira+Platelet activation-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.279	0.0633	no	no	no	dn	no	up	DM-DS
Lachnospira	MCP-1(MCAF)	Lachnospira-Progesterone-mediated oocyte maturation+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.279	0.0633	no	no	no	dn	no	up	DM-DS
Lachnospira	MCP-1(MCAF)	Lachnospira+Rap1 signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.279	0.0633	no	no	no	dn	no	up	DM-DS
Lachnospira	MCP-1(MCAF)	Lachnospira-Spliceosome+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.279	0.0633	no	no	no	dn	no	up	DM-DS
Lachnospira	MCP-1(MCAF)	Lachnospira+Leukocyte transendothelial migration-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.279	0.0633	no	no	no	dn	no	up	DM-DS
Lachnospira	MCP-1(MCAF)	Lachnospira+Oxytocin signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.279	0.0633	no	no	no	dn	no	up	DM-DS
Lachnospira	MCP-1(MCAF)	Lachnospira+Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.279	0.0633	no	no	no	dn	no	up	DM-DS
Fusobacterium	MCP-1(MCAF)	Fusobacterium-Intestinal immune network for IgA production-L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.628	0.0633	no	no	no	dn	no	up	DM-DS
Fusobacterium	MCP-1(MCAF)	Fusobacterium-Intestinal immune network for IgA production-Progesterone-mediated oocyte maturation+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.628	0.0633	no	no	no	dn	no	up	DM-DS
Fusobacterium	MCP-1(MCAF)	Fusobacterium-Intestinal immune network for IgA production-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.628	0.0633	no	no	no	dn	no	up	DM-DS
Fusobacterium	MCP-1(MCAF)	Fusobacterium-18:0/18:0-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.628	0.0633	no	no	no	dn	no	up	DM-DS
Fusobacterium	MCP-1(MCAF)	Fusobacterium-16:0/20:3-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.628	0.0633	no	no	no	dn	no	up	DM-DS
Fusobacterium	MCP-1(MCAF)	Fusobacterium-18:0/18:1-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.628	0.0633	no	no	no	dn	no	up	DM-DS
Fusobacterium	MCP-1(MCAF)	Fusobacterium-GUDCA+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.628	0.0633	no	no	no	dn	no	up	DM-DS
Fusobacterium	MCP-1(MCAF)	Fusobacterium-16:0/18:2-PC+blood-16:0/20:4-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.628	0.0633	no	no	no	dn	no	up	DM-DS
GCDCA+stool	MCP-1(MCAF)	GCDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0633	no	dn	no	dn	no	up	DM-DS
GCDCA+stool	MCP-1(MCAF)	GCDCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0633	no	dn	no	dn	no	up	DM-DS
GCDCA+stool	MCP-1(MCAF)	GCDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0633	no	dn	no	dn	no	up	DM-DS
GCDCA+stool	MCP-1(MCAF)	GCDCA+stool+16:0/18:2-PC+blood-16:0/20:4-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0633	no	dn	no	dn	no	up	DM-DS
GCDCA+stool	MCP-1(MCAF)	GCDCA+stool+16:0/16:1-PC+blood+16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0633	no	dn	no	dn	no	up	DM-DS
GCDCA+stool	MCP-1(MCAF)	GCDCA+stool+16:1/18:2-PG+blood+18:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0633	no	dn	no	dn	no	up	DM-DS
5-Hydroxytryptamine+stool	MCP-1(MCAF)	5-Hydroxytryptamine+stool+Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0633	dn	dn	no	dn	no	up	DM-DS
5-Hydroxytryptamine+stool	MCP-1(MCAF)	5-Hydroxytryptamine+stool+Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0633	dn	dn	no	dn	no	up	DM-DS
5-Hydroxytryptamine+stool	MCP-1(MCAF)	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0633	dn	dn	no	dn	no	up	DM-DS
5-Hydroxytryptamine+stool	MCP-1(MCAF)	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:1-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0633	dn	dn	no	dn	no	up	DM-DS
5-Hydroxytryptamine+stool	MCP-1(MCAF)	5-Hydroxytryptamine+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0633	dn	dn	no	dn	no	up	DM-DS
5-Hydroxytryptamine+stool	MCP-1(MCAF)	5-Hydroxytryptamine+stool-nutriCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0633	dn	dn	no	dn	no	up	DM-DS
5-Hydroxytryptamine+stool	MCP-1(MCAF)	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:0-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0633	dn	dn	no	dn	no	up	DM-DS
5-Hydroxytryptamine+stool	MCP-1(MCAF)	5-Hydroxytryptamine+stool-nutriCA+stool-13-HODE+blood-16:0/20:4-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0633	dn	dn	no	dn	no	up	DM-DS
5-Hydroxytryptamine+stool	MCP-1(MCAF)	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/22:6-PA+blood-P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0633	dn	dn	no	dn	no	up	DM-DS
5-Hydroxytryptamine+stool	MCP-1(MCAF)	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0633	dn	dn	no	dn	no	up	DM-DS
5-Hydroxytryptamine+stool	MCP-1(MCAF)	5-Hydroxytryptamine+stool-nutriCA+stool-AA+blood+L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0633	dn	dn	no	dn	no	up	DM-DS
Odoribacter	MCP-1(MCAF)	Odoribacter-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.798	0.0633	no	no	no	dn	no	up	DM-DS
Odoribacter	MCP-1(MCAF)	Odoribacter+Neuroactive ligand-receptor interaction-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.798	0.0633	no	no	no	dn	no	up	DM-DS
Odoribacter	MCP-1(MCAF)	Odoribacter+16:0/20:4-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.798	0.0633	no	no	no	dn	no	up	DM-DS
Actinomyces	MCP-1(MCAF)	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.621	0.0633	no	no	no	dn	no	up	DM-DS
Actinomyces	MCP-1(MCAF)	Actinomyces+Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.621	0.0633	no	no	no	dn	no	up	DM-DS
Actinomyces	MCP-1(MCAF)	Actinomyces+Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.621	0.0633	no	no	no	dn	no	up	DM-DS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-DS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-DS
2-hydroxyphenylacetic acid+urine	MCP-1(MCAF)	"2-hydroxyphenylacetic acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+MCP-1(MCAF)"	Indirect	urine_cometabolism	serum_cytokines	0.763	0.0633	no	no	no	dn	no	up	DM-DS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-DS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-DS
Caproic acid+stool	MCP-1(MCAF)	Caproic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.882	0.0633	no	no	no	dn	no	up	DM-DS
Caproic acid+stool	MCP-1(MCAF)	Caproic acid+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.882	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella+AMPK signaling pathway-Neutrophil extracellular trap formation-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella+Phosphatidylinositol signaling system-Neutrophil extracellular trap formation-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella+AMPK signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella-Yersinia infection+Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella-Influenza A+Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella-Yersinia infection-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella+Phosphatidylinositol signaling system+Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella-Influenza A-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella-Yersinia infection-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella-Influenza A-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella-Yersinia infection-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella+Phosphatidylinositol signaling system+Progesterone-mediated oocyte maturation+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella+AMPK signaling pathway-IL-17 signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella+Phosphatidylinositol signaling system-IL-17 signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella+AMPK signaling pathway+L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella+Phosphatidylinositol signaling system-Lysosome-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella+Phosphatidylinositol signaling system+p53 signaling pathway+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella+AMPK signaling pathway-Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella-Yersinia infection+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella+Phosphatidylinositol signaling system-Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella-Influenza A+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella-Yersinia infection+18:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Eggerthella	MCP-1(MCAF)	Eggerthella+Phosphatidylinositol signaling system-18:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	DM-DS
Anaerotruncus	MCP-1(MCAF)	"Anaerotruncus-Ruminococcus-18:2n6c+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.904	0.0633	no	no	no	dn	no	up	DM-DS
Anaerotruncus	MCP-1(MCAF)	Anaerotruncus-Ruminococcus-Alcoholism+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.904	0.0633	no	no	no	dn	no	up	DM-DS
Anaerotruncus	MCP-1(MCAF)	Anaerotruncus-Ruminococcus-Alcoholism-Measles+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.904	0.0633	no	no	no	dn	no	up	DM-DS
Anaerotruncus	MCP-1(MCAF)	Anaerotruncus-Ruminococcus-Serotonergic synapse-Measles+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.904	0.0633	no	no	no	dn	no	up	DM-DS
Anaerotruncus	MCP-1(MCAF)	Anaerotruncus-Ruminococcus-20:4-LPC+blood+L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.904	0.0633	no	no	no	dn	no	up	DM-DS
Anaerotruncus	MCP-1(MCAF)	Anaerotruncus-Ruminococcus-EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.904	0.0633	no	no	no	dn	no	up	DM-DS
Anaerotruncus	MCP-1(MCAF)	Anaerotruncus-Ruminococcus+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.904	0.0633	no	no	no	dn	no	up	DM-DS
Anaerotruncus	MCP-1(MCAF)	Anaerotruncus-Ruminococcus-18:3n3+blood+L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.904	0.0633	no	no	no	dn	no	up	DM-DS
Anaerotruncus	MCP-1(MCAF)	Anaerotruncus-Ruminococcus+18:0/18:0-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.904	0.0633	no	no	no	dn	no	up	DM-DS
Anaerostipes	MCP-1(MCAF)	Anaerostipes+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.568	0.0633	no	no	no	dn	no	up	DM-DS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-DS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool+9-HODE+blood+AA+blood+L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-DS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-DS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-14:0/18:2-PC+blood+24:0+blood-P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-DS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-DS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-d18:1-14:0-SM+blood-L-Asparagine+blood+L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-DS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-DS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-DS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-DS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-DS
Paraprevotella	MCP-1(MCAF)	Paraprevotella-IL-17 signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.118	0.0633	no	no	no	dn	no	up	DM-DS
¦Ø-MCA+stool	MCP-1(MCAF)	¦Ø-MCA+stool-L-Tyrosine+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.919	0.0633	no	no	no	dn	no	up	DM-DS
¦Ø-MCA+stool	MCP-1(MCAF)	¦Ø-MCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.919	0.0633	no	no	no	dn	no	up	DM-DS
Phenylacetic acid+stool	MCP-1(MCAF)	Phenylacetic acid+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+PI3K-Akt signaling pathway+Measles+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	"Gemmiger-12,13-EPOME+blood+16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Platelet activation-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+ErbB signaling pathway-Platelet activation-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+ErbB signaling pathway+p53 signaling pathway+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Progesterone-mediated oocyte maturation+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+ErbB signaling pathway+Progesterone-mediated oocyte maturation+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+Pathways in cancer-Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+ErbB signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+Gastric cancer-Fluid shear stress and atherosclerosis-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+Gastric cancer-Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+24:0+blood-P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+Pathways in cancer-16:0/20:4-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+Pathways in cancer+L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Leukocyte transendothelial migration-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Neutrophil extracellular trap formation-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Oxytocin signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
Gemmiger	MCP-1(MCAF)	Gemmiger+ErbB signaling pathway-Oxytocin signaling pathway-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-DS
GDCA+stool	MCP-1(MCAF)	GDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.656	0.0633	no	no	no	dn	no	up	DM-DS
GDCA+stool	MCP-1(MCAF)	GDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.656	0.0633	no	no	no	dn	no	up	DM-DS
GDCA+stool	MCP-1(MCAF)	"GDCA+stool+L-Lysine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+MCP-1(MCAF)"	Indirect	stool_bileacids	serum_cytokines	0.656	0.0633	no	no	no	dn	no	up	DM-DS
Methanobrevibacter	MCP-1(MCAF)	Methanobrevibacter-Alcoholism-Measles+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.629	0.0633	no	no	no	dn	no	up	DM-DS
Methanobrevibacter	MCP-1(MCAF)	Methanobrevibacter-Alcoholism+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.629	0.0633	no	no	no	dn	no	up	DM-DS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-DS
CDCA+stool	MCP-1(MCAF)	CDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.663	0.0633	no	no	no	dn	no	up	DM-DS
CDCA+stool	MCP-1(MCAF)	CDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.663	0.0633	no	no	no	dn	no	up	DM-DS
CA+stool	MCP-1(MCAF)	CA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	DM-DS
HDCA+blood	MCP-1(MCAF)	HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.483	0.0633	no	no	no	dn	no	up	DM-DS
UDCA+stool	MCP-1(MCAF)	UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-DS
TDCA+stool	MCP-1(MCAF)	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-DS
TDCA+stool	MCP-1(MCAF)	TDCA+stool-12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-DS
TDCA+stool	MCP-1(MCAF)	TDCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-DS
TDCA+stool	MCP-1(MCAF)	TDCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-DS
TDCA+stool	MCP-1(MCAF)	TDCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-DS
TDCA+stool	MCP-1(MCAF)	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-DS
TDCA+stool	MCP-1(MCAF)	TDCA+stool-HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-DS
TDCA+stool	MCP-1(MCAF)	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	MCP-1(MCAF)	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A+IL-4+MCP-1(MCAF)	Indirect	urine_cometabolism	serum_cytokines	0.973	0.0633	no	no	no	dn	no	up	DM-DS
Desulfovibrio	MCP-1(MCAF)	Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.27	0.0633	no	no	no	dn	no	up	DM-DS
Desulfovibrio	MCP-1(MCAF)	Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.27	0.0633	no	no	no	dn	no	up	DM-DS
Desulfovibrio	MCP-1(MCAF)	Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.27	0.0633	no	no	no	dn	no	up	DM-DS
Desulfovibrio	MCP-1(MCAF)	Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.27	0.0633	no	no	no	dn	no	up	DM-DS
Desulfovibrio	MCP-1(MCAF)	Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.27	0.0633	no	no	no	dn	no	up	DM-DS
Desulfovibrio	MCP-1(MCAF)	Desulfovibrio+Antigen processing and presentation-Progesterone-mediated oocyte maturation+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.27	0.0633	no	no	no	dn	no	up	DM-DS
Desulfovibrio	MCP-1(MCAF)	Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.27	0.0633	no	no	no	dn	no	up	DM-DS
Desulfovibrio	MCP-1(MCAF)	Desulfovibrio+Antigen processing and presentation+Leukocyte transendothelial migration-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.27	0.0633	no	no	no	dn	no	up	DM-DS
Desulfovibrio	MCP-1(MCAF)	Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.27	0.0633	no	no	no	dn	no	up	DM-DS
Desulfovibrio	MCP-1(MCAF)	Desulfovibrio+Human cytomegalovirus infection-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.27	0.0633	no	no	no	dn	no	up	DM-DS
Desulfovibrio	MCP-1(MCAF)	Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.27	0.0633	no	no	no	dn	no	up	DM-DS
Desulfovibrio	MCP-1(MCAF)	Desulfovibrio+Antigen processing and presentation-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.27	0.0633	no	no	no	dn	no	up	DM-DS
Desulfovibrio	MCP-1(MCAF)	Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.27	0.0633	no	no	no	dn	no	up	DM-DS
nutriCA+stool	MCP-1(MCAF)	nutriCA+stool+18:0/22:6-PA+blood-P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.481	0.0633	no	no	no	dn	no	up	DM-DS
nutriCA+stool	MCP-1(MCAF)	nutriCA+stool+18:0/18:1-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.481	0.0633	no	no	no	dn	no	up	DM-DS
nutriCA+stool	MCP-1(MCAF)	nutriCA+stool+18:0/18:0-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.481	0.0633	no	no	no	dn	no	up	DM-DS
nutriCA+stool	MCP-1(MCAF)	nutriCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.481	0.0633	no	no	no	dn	no	up	DM-DS
nutriCA+stool	MCP-1(MCAF)	nutriCA+stool-13-HODE+blood-16:0/20:4-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.481	0.0633	no	no	no	dn	no	up	DM-DS
nutriCA+stool	MCP-1(MCAF)	nutriCA+stool-AA+blood+L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.481	0.0633	no	no	no	dn	no	up	DM-DS
nutriCA+stool	MCP-1(MCAF)	nutriCA+stool+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.481	0.0633	no	no	no	dn	no	up	DM-DS
Bilophila	MCP-1(MCAF)	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.528	0.0633	no	no	no	dn	no	up	DM-DS
Bilophila	MCP-1(MCAF)	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.528	0.0633	no	no	no	dn	no	up	DM-DS
Bilophila	MCP-1(MCAF)	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.528	0.0633	no	no	no	dn	no	up	DM-DS
Bilophila	MCP-1(MCAF)	Bilophila+Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.528	0.0633	no	no	no	dn	no	up	DM-DS
Bilophila	MCP-1(MCAF)	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.528	0.0633	no	no	no	dn	no	up	DM-DS
Bilophila	MCP-1(MCAF)	Bilophila+Desulfovibrio+Antigen processing and presentation-Progesterone-mediated oocyte maturation+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.528	0.0633	no	no	no	dn	no	up	DM-DS
Bilophila	MCP-1(MCAF)	Bilophila+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.528	0.0633	no	no	no	dn	no	up	DM-DS
Bilophila	MCP-1(MCAF)	Bilophila+Desulfovibrio+Antigen processing and presentation+Leukocyte transendothelial migration-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.528	0.0633	no	no	no	dn	no	up	DM-DS
Bilophila	MCP-1(MCAF)	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.528	0.0633	no	no	no	dn	no	up	DM-DS
Bilophila	MCP-1(MCAF)	Bilophila+Desulfovibrio+Human cytomegalovirus infection-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.528	0.0633	no	no	no	dn	no	up	DM-DS
Bilophila	MCP-1(MCAF)	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.528	0.0633	no	no	no	dn	no	up	DM-DS
Bilophila	MCP-1(MCAF)	Bilophila+Desulfovibrio+Antigen processing and presentation-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.528	0.0633	no	no	no	dn	no	up	DM-DS
Bilophila	MCP-1(MCAF)	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool+Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.528	0.0633	no	no	no	dn	no	up	DM-DS
GDCA+blood	MCP-1(MCAF)	GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.632	0.0633	no	no	no	dn	no	up	DM-DS
P-hydroxyhippuric acid+urine	MCP-1(MCAF)	P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	urine_cometabolism	serum_cytokines	0.436	0.0633	no	no	no	dn	no	up	DM-DS
acetic acid C2+blood	MCP-1(MCAF)	acetic acid C2+blood+d18:1-20:1-SM+blood-GUDCA+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.000193	0.0633	up	dn	no	dn	no	up	DM-DS
isovaleric acid iso-C5+blood	MCP-1(MCAF)	isovaleric acid iso-C5+blood+n3+blood-FGF basic+IL-17A+IL-4+MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.117	0.0633	no	no	no	dn	no	up	DM-DS
isovaleric acid iso-C5+blood	MCP-1(MCAF)	isovaleric acid iso-C5+blood+PUFA+blood+SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.117	0.0633	no	no	no	dn	no	up	DM-DS
Clostridium	MCP-1(MCAF)	Clostridium-Eotaxin+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.925	0.0633	no	no	no	dn	no	up	DM-DS
T-¦Á-MCA+stool	MCP-1(MCAF)	T-¦Á-MCA+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.48	0.0633	no	no	no	dn	no	up	DM-DS
12-ketoDCA+blood	MCP-1(MCAF)	12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.517	0.0633	no	no	no	dn	no	up	DM-DS
12-ketoDCA+blood	MCP-1(MCAF)	12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.517	0.0633	no	no	no	dn	no	up	DM-DS
12-ketoDCA+blood	MCP-1(MCAF)	12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.517	0.0633	no	no	no	dn	no	up	DM-DS
12-ketoDCA+blood	MCP-1(MCAF)	12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.517	0.0633	no	no	no	dn	no	up	DM-DS
12-ketoDCA+blood	MCP-1(MCAF)	12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.517	0.0633	no	no	no	dn	no	up	DM-DS
12-ketoDCA+blood	MCP-1(MCAF)	12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.517	0.0633	no	no	no	dn	no	up	DM-DS
12-ketoDCA+blood	MCP-1(MCAF)	12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.517	0.0633	no	no	no	dn	no	up	DM-DS
Butyricicoccus	MCP-1(MCAF)	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood-Eotaxin+MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-DS
Blautia	RANTES	Blautia+UDCA+stool-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	DM-DS
Blautia	RANTES	Blautia-iso-LCA+blood+RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	DM-DS
Blautia	RANTES	Blautia+CA+stool-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	DM-DS
Blautia	RANTES	Blautia+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	DM-DS
Blautia	RANTES	Blautia-L-Homocystine+blood+RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	DM-DS
Blautia	RANTES	Blautia+CDCA+stool-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	DM-DS
Blautia	RANTES	Blautia+GCA+stool-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	DM-DS
Blautia	RANTES	Blautia-MIP-1b+RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	DM-DS
Parabacteroides	RANTES	Parabacteroides-TCA+stool-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	DM-DS
Dorea	RANTES	Dorea+UDCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	DM-DS
Dorea	RANTES	Dorea+Glycolysis / Gluconeogenesis-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	DM-DS
Dorea	RANTES	Dorea+GCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	DM-DS
Dorea	RANTES	Dorea+Carbon metabolism-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	DM-DS
Dorea	RANTES	Dorea+CA+stool-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	DM-DS
Dorea	RANTES	Dorea+CDCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	DM-DS
Faecalibacterium	RANTES	Faecalibacterium-Phenylacetic acid+stool-L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.0039	0.0757	no	dn	dn	no	no	up	DM-DS
Faecalibacterium	RANTES	Faecalibacterium+GCDCA+stool+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.0039	0.0757	no	dn	dn	no	no	up	DM-DS
Faecalibacterium	RANTES	Faecalibacterium+GCDCA+stool+16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.0039	0.0757	no	dn	dn	no	no	up	DM-DS
Faecalibacterium	RANTES	Faecalibacterium+GCDCA+stool+UDCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.0039	0.0757	no	dn	dn	no	no	up	DM-DS
TUDCA+blood	RANTES	TUDCA+blood-TXB2+blood+Homovanillic acid+urine-MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.0282	0.0757	no	no	dn	no	no	up	DM-DS
Bacteroides	RANTES	Bacteroides-Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.000267	0.0757	dn	dn	up	no	no	up	DM-DS
Bacteroides	RANTES	Bacteroides+Glycolysis / Gluconeogenesis-RANTES	Indirect	Genus	serum_cytokines	0.000267	0.0757	dn	dn	up	no	no	up	DM-DS
Bacteroides	RANTES	Bacteroides+Leishmaniasis-RANTES	Indirect	Genus	serum_cytokines	0.000267	0.0757	dn	dn	up	no	no	up	DM-DS
Bacteroides	RANTES	Bacteroides-16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.000267	0.0757	dn	dn	up	no	no	up	DM-DS
Propionic acid+stool	RANTES	Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+IL-9+RANTES	Indirect	stool_scfa	serum_cytokines	0.0436	0.0757	dn	no	up	no	no	up	DM-DS
Propionic acid+stool	RANTES	Propionic acid+stool+18:0-LPE+blood-DPA+blood-L-Homocystine+blood+RANTES	Indirect	stool_scfa	serum_cytokines	0.0436	0.0757	dn	no	up	no	no	up	DM-DS
Propionic acid+stool	RANTES	Propionic acid+stool+d18:1-20:1-SM+blood+HDCA+blood+L-Homocystine+blood+RANTES	Indirect	stool_scfa	serum_cytokines	0.0436	0.0757	dn	no	up	no	no	up	DM-DS
Propionic acid+stool	RANTES	Propionic acid+stool+d18:1-20:1-SM+blood+d18:1-22:1-SM+blood+iso-LCA+blood+RANTES	Indirect	stool_scfa	serum_cytokines	0.0436	0.0757	dn	no	up	no	no	up	DM-DS
Propionic acid+stool	RANTES	Propionic acid+stool+d18:1-18:1-SM+blood+d18:1-22:1-SM+blood+iso-LCA+blood+RANTES	Indirect	stool_scfa	serum_cytokines	0.0436	0.0757	dn	no	up	no	no	up	DM-DS
Propionic acid+stool	RANTES	Propionic acid+stool+d18:1-20:1-SM+blood+HDCA+blood+iso-LCA+blood+RANTES	Indirect	stool_scfa	serum_cytokines	0.0436	0.0757	dn	no	up	no	no	up	DM-DS
Propionic acid+stool	RANTES	Propionic acid+stool-16:0/16:0-PC+blood-GDCA+blood+iso-LCA+blood+RANTES	Indirect	stool_scfa	serum_cytokines	0.0436	0.0757	dn	no	up	no	no	up	DM-DS
Propionic acid+stool	RANTES	Propionic acid+stool-L-Tyrosine+blood+IP-10+MIP-1b+RANTES	Indirect	stool_scfa	serum_cytokines	0.0436	0.0757	dn	no	up	no	no	up	DM-DS
Propionic acid+stool	RANTES	Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+MIP-1b+RANTES	Indirect	stool_scfa	serum_cytokines	0.0436	0.0757	dn	no	up	no	no	up	DM-DS
Propionic acid+stool	RANTES	Propionic acid+stool+d18:1-20:1-SM+blood+Homovanillic acid+urine-MIP-1b+RANTES	Indirect	stool_scfa	serum_cytokines	0.0436	0.0757	dn	no	up	no	no	up	DM-DS
Propionic acid+stool	RANTES	Propionic acid+stool+d18:1-18:1-SM+blood+Homovanillic acid+urine-MIP-1b+RANTES	Indirect	stool_scfa	serum_cytokines	0.0436	0.0757	dn	no	up	no	no	up	DM-DS
Propionic acid+stool	RANTES	Propionic acid+stool+d18:1-20:1-SM+blood-decanoic acid C10+blood+L-Isoleucine+blood-RANTES	Indirect	stool_scfa	serum_cytokines	0.0436	0.0757	dn	no	up	no	no	up	DM-DS
Propionic acid+stool	RANTES	Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-6-RANTES	Indirect	stool_scfa	serum_cytokines	0.0436	0.0757	dn	no	up	no	no	up	DM-DS
[Ruminococcus]	RANTES	[Ruminococcus]-Progesterone-mediated oocyte maturation+RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	DM-DS
[Ruminococcus]	RANTES	[Ruminococcus]-ErbB signaling pathway+RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	DM-DS
[Ruminococcus]	RANTES	[Ruminococcus]-Platinum drug resistance+RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	DM-DS
[Ruminococcus]	RANTES	[Ruminococcus]-Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	DM-DS
[Ruminococcus]	RANTES	[Ruminococcus]-Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	DM-DS
GUDCA+blood	RANTES	GUDCA+blood+UDCA+blood+Eotaxin+IL-9+RANTES	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0757	no	no	dn	no	no	up	DM-DS
GUDCA+blood	RANTES	GUDCA+blood+UDCA+blood+Eotaxin+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0757	no	no	dn	no	no	up	DM-DS
GUDCA+blood	RANTES	GUDCA+blood+UDCA+blood+Eotaxin-IL-6-RANTES	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0757	no	no	dn	no	no	up	DM-DS
UDCA+blood	RANTES	UDCA+blood+Eotaxin-IL-6-RANTES	Indirect	serum_bileacids	serum_cytokines	0.0939	0.0757	no	no	dn	no	no	up	DM-DS
UDCA+blood	RANTES	UDCA+blood+Eotaxin+IL-9+RANTES	Indirect	serum_bileacids	serum_cytokines	0.0939	0.0757	no	no	dn	no	no	up	DM-DS
UDCA+blood	RANTES	UDCA+blood+Eotaxin+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.0939	0.0757	no	no	dn	no	no	up	DM-DS
Acetic acid+stool	RANTES	Acetic acid+stool-16:0/18:0-PS+blood-iso-LCA+blood+RANTES	Indirect	stool_scfa	serum_cytokines	0.0656	0.0757	dn	no	no	no	no	up	DM-DS
Acetic acid+stool	RANTES	Acetic acid+stool-18:0/18:0-PS+blood-iso-LCA+blood+RANTES	Indirect	stool_scfa	serum_cytokines	0.0656	0.0757	dn	no	no	no	no	up	DM-DS
Acetic acid+stool	RANTES	Acetic acid+stool+L-Histidine+blood+L-Isoleucine+blood-RANTES	Indirect	stool_scfa	serum_cytokines	0.0656	0.0757	dn	no	no	no	no	up	DM-DS
Alistipes	RANTES	Alistipes+nutriCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	DM-DS
Alistipes	RANTES	Alistipes-IL-6-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	DM-DS
Alistipes	RANTES	Alistipes+Platinum drug resistance+RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	DM-DS
Butyricimonas	RANTES	Butyricimonas-L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.17	0.0757	no	no	no	no	no	up	DM-DS
Collinsella	RANTES	Collinsella-GnRH signaling pathway+iso-LCA+stool+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-DS
Collinsella	RANTES	Collinsella-GnRH signaling pathway+iso-LCA+blood+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-DS
Collinsella	RANTES	Collinsella-d18:1-22:1-SM+blood+iso-LCA+blood+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-DS
Collinsella	RANTES	Collinsella-GnRH signaling pathway+L-Homocystine+blood+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-DS
Collinsella	RANTES	Collinsella-GnRH signaling pathway+LCA+stool+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-DS
Collinsella	RANTES	Collinsella-GnRH signaling pathway-CDCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-DS
Collinsella	RANTES	Collinsella-GnRH signaling pathway-CA+stool-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-DS
Collinsella	RANTES	Collinsella-GnRH signaling pathway-UDCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-DS
Collinsella	RANTES	Collinsella-GnRH signaling pathway+Chemical carcinogenesis - receptor activation+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-DS
Collinsella	RANTES	Collinsella-Endocrine and other factor-regulated calcium reabsorption+Chemical carcinogenesis - receptor activation+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-DS
Collinsella	RANTES	Collinsella-GnRH signaling pathway+12-ketoDCA+blood+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-DS
Collinsella	RANTES	Collinsella-GnRH signaling pathway-Epstein-Barr virus infection-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-DS
Collinsella	RANTES	Collinsella-Renin secretion+Bacterial invasion of epithelial cells-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-DS
Collinsella	RANTES	Collinsella-GnRH signaling pathway-GCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-DS
Collinsella	RANTES	Collinsella-GnRH signaling pathway-18:0/20:3-PI+blood-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-DS
Collinsella	RANTES	Collinsella-Renin secretion-Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-DS
5-Hydroxytryptamine+urine	RANTES	5-Hydroxytryptamine+urine-Hippuric acid+urine-IL-6-RANTES	Indirect	urine_cometabolism	serum_cytokines	0.171	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Viral carcinogenesis+16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Osteoclast differentiation+16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Cellular senescence+16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Human papillomavirus infection+16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Apoptosis+16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Toll-like receptor signaling pathway+16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Fc epsilon RI signaling pathway+16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+C-type lectin receptor signaling pathway+16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Prolactin signaling pathway+16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-Glucagon signaling pathway+Chemical carcinogenesis - receptor activation+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Cellular senescence-Chemical carcinogenesis - receptor activation+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-Amphetamine addiction+Chemical carcinogenesis - receptor activation+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-GnRH signaling pathway+Chemical carcinogenesis - receptor activation+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-Aldosterone synthesis and secretion+Chemical carcinogenesis - receptor activation+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-Dopaminergic synapse-GCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Cellular senescence+GCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-GnRH signaling pathway-GCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-Aldosterone synthesis and secretion-GCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-Dopaminergic synapse+L-Homocystine+blood+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Cellular senescence-L-Homocystine+blood+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Human papillomavirus infection-L-Homocystine+blood+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-GnRH signaling pathway+L-Homocystine+blood+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-Aldosterone synthesis and secretion+L-Homocystine+blood+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Cellular senescence+Antigen processing and presentation-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Acute myeloid leukemia+Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Human papillomavirus infection+Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+NF-kappa B signaling pathway+Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Insulin resistance+Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-Circadian entrainment-Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Neurotrophin signaling pathway+Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Chronic myeloid leukemia+Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Toll-like receptor signaling pathway+Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+RIG-I-like receptor signaling pathway+Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Fc epsilon RI signaling pathway+Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Prostate cancer+Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+C-type lectin receptor signaling pathway+Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Prolactin signaling pathway+Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+TNF signaling pathway+Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+B cell receptor signaling pathway+Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Cellular senescence+Epstein-Barr virus infection-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-GnRH signaling pathway-Epstein-Barr virus infection-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Cellular senescence+CDCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Human papillomavirus infection+CDCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-GnRH signaling pathway-CDCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Cellular senescence-LCA+stool+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-GnRH signaling pathway+LCA+stool+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-Aldosterone synthesis and secretion+LCA+stool+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Cellular senescence-iso-LCA+stool+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-GnRH signaling pathway+iso-LCA+stool+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Cellular senescence+UDCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-GnRH signaling pathway-UDCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+NF-kappa B signaling pathway-Asthma-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Insulin resistance-Asthma-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+RIG-I-like receptor signaling pathway-Asthma-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+NF-kappa B signaling pathway-Bacterial invasion of epithelial cells-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Insulin resistance-Bacterial invasion of epithelial cells-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-Circadian entrainment+Bacterial invasion of epithelial cells-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+RIG-I-like receptor signaling pathway-Bacterial invasion of epithelial cells-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+TNF signaling pathway-Bacterial invasion of epithelial cells-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+NF-kappa B signaling pathway-Leishmaniasis-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+NF-kappa B signaling pathway+Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Insulin resistance+Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Neurotrophin signaling pathway+Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Toll-like receptor signaling pathway+Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+RIG-I-like receptor signaling pathway+Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Fc epsilon RI signaling pathway+Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+C-type lectin receptor signaling pathway+Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Prolactin signaling pathway+Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+TNF signaling pathway+Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+B cell receptor signaling pathway+Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-GnRH signaling pathway+iso-LCA+blood+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+Chronic myeloid leukemia+MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina+IP-10+MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-GnRH signaling pathway-CA+stool-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-GnRH signaling pathway+12-ketoDCA+blood+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Sarcina	RANTES	Sarcina-GnRH signaling pathway-18:0/20:3-PI+blood-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Methanosphaera	RANTES	Methanosphaera-Roseburia+GCDCA+stool+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Methanosphaera	RANTES	Methanosphaera-Roseburia-Phenylacetic acid+stool-L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Methanosphaera	RANTES	Methanosphaera-Roseburia+16:0/16:1-PC+blood+18:0/20:3-PI+blood-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Methanosphaera	RANTES	Methanosphaera-Roseburia+IP-10+MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Methanosphaera	RANTES	Methanosphaera-Roseburia+GCDCA+stool+16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
Methanosphaera	RANTES	Methanosphaera-Roseburia+GCDCA+stool+UDCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.0703	0.0757	no	no	no	no	no	up	DM-DS
iso-DCA+stool	RANTES	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+IL-9+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	DM-DS
iso-DCA+stool	RANTES	iso-DCA+stool+Propionic acid+stool+18:0-LPE+blood-DPA+blood-L-Homocystine+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	DM-DS
iso-DCA+stool	RANTES	iso-DCA+stool+Propionic acid+stool+d18:1-20:1-SM+blood+HDCA+blood+L-Homocystine+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	DM-DS
iso-DCA+stool	RANTES	iso-DCA+stool+Propionic acid+stool+d18:1-20:1-SM+blood+d18:1-22:1-SM+blood+iso-LCA+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	DM-DS
iso-DCA+stool	RANTES	iso-DCA+stool+Propionic acid+stool+d18:1-18:1-SM+blood+d18:1-22:1-SM+blood+iso-LCA+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	DM-DS
iso-DCA+stool	RANTES	iso-DCA+stool+Propionic acid+stool+d18:1-20:1-SM+blood+HDCA+blood+iso-LCA+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	DM-DS
iso-DCA+stool	RANTES	iso-DCA+stool+Propionic acid+stool-16:0/16:0-PC+blood-GDCA+blood+iso-LCA+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	DM-DS
iso-DCA+stool	RANTES	iso-DCA+stool+Propionic acid+stool-L-Tyrosine+blood+IP-10+MIP-1b+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	DM-DS
iso-DCA+stool	RANTES	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+MIP-1b+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	DM-DS
iso-DCA+stool	RANTES	iso-DCA+stool+Propionic acid+stool+d18:1-20:1-SM+blood+Homovanillic acid+urine-MIP-1b+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	DM-DS
iso-DCA+stool	RANTES	iso-DCA+stool+Propionic acid+stool+d18:1-18:1-SM+blood+Homovanillic acid+urine-MIP-1b+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	DM-DS
iso-DCA+stool	RANTES	iso-DCA+stool+Propionic acid+stool+d18:1-20:1-SM+blood-decanoic acid C10+blood+L-Isoleucine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	DM-DS
iso-DCA+stool	RANTES	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-6-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	DM-DS
LCA+stool	RANTES	LCA+stool+RANTES	Direct	stool_bileacids	serum_cytokines	0.314	0.0757	no	no	no	no	no	up	DM-DS
Akkermansia	RANTES	Akkermansia-Longevity regulating pathway-Leishmaniasis-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	DM-DS
Akkermansia	RANTES	Akkermansia-Cholinergic synapse-L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	DM-DS
Akkermansia	RANTES	Akkermansia-Longevity regulating pathway-Leukocyte transendothelial migration-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	DM-DS
Akkermansia	RANTES	Akkermansia-Cholinergic synapse-TCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	DM-DS
Akkermansia	RANTES	Akkermansia-Longevity regulating pathway-Asthma-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	DM-DS
Akkermansia	RANTES	Akkermansia-Breast cancer-Asthma-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	DM-DS
Akkermansia	RANTES	Akkermansia-Longevity regulating pathway-UDCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	DM-DS
Akkermansia	RANTES	Akkermansia-Longevity regulating pathway-CDCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	DM-DS
Akkermansia	RANTES	Akkermansia-Longevity regulating pathway-CA+stool-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	DM-DS
Akkermansia	RANTES	Akkermansia-Longevity regulating pathway-Bacterial invasion of epithelial cells-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	DM-DS
Akkermansia	RANTES	Akkermansia-Longevity regulating pathway+Chemical carcinogenesis - receptor activation+RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	DM-DS
Akkermansia	RANTES	Akkermansia-Longevity regulating pathway-GCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	DM-DS
Bifidobacterium	RANTES	Bifidobacterium+Bacterial invasion of epithelial cells-RANTES	Indirect	Genus	serum_cytokines	0.105	0.0757	no	dn	no	no	no	up	DM-DS
Bifidobacterium	RANTES	Bifidobacterium+Glycolysis / Gluconeogenesis-RANTES	Indirect	Genus	serum_cytokines	0.105	0.0757	no	dn	no	no	no	up	DM-DS
Bifidobacterium	RANTES	Bifidobacterium+CA+stool-RANTES	Indirect	Genus	serum_cytokines	0.105	0.0757	no	dn	no	no	no	up	DM-DS
Bifidobacterium	RANTES	Bifidobacterium+Leukocyte transendothelial migration-RANTES	Indirect	Genus	serum_cytokines	0.105	0.0757	no	dn	no	no	no	up	DM-DS
3-Hydroxytyramine hydrochloride+urine	RANTES	3-Hydroxytyramine hydrochloride+urine-Hippuric acid+urine-IL-6-RANTES	Indirect	urine_cometabolism	serum_cytokines	0.288	0.0757	no	no	no	no	no	up	DM-DS
Ruminococcus	RANTES	Ruminococcus+nutriCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-DS
GCDCA+blood	RANTES	GCDCA+blood-TXB2+blood+Homovanillic acid+urine-MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.31	0.0757	no	no	no	no	no	up	DM-DS
GCDCA+blood	RANTES	GCDCA+blood+L-Tyrosine+blood+IP-10+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.31	0.0757	no	no	no	no	no	up	DM-DS
ACA+blood	RANTES	ACA+blood-decanoic acid C10+blood+L-Isoleucine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.338	0.0757	no	no	no	no	no	up	DM-DS
DCA+stool	RANTES	DCA+stool+iso-LCA+stool+RANTES	Indirect	stool_bileacids	serum_cytokines	0.195	0.0757	no	no	no	no	no	up	DM-DS
DCA+stool	RANTES	DCA+stool-TDCA+stool-RANTES	Indirect	stool_bileacids	serum_cytokines	0.195	0.0757	no	no	no	no	no	up	DM-DS
DCA+stool	RANTES	DCA+stool+MIP-1b+RANTES	Indirect	stool_bileacids	serum_cytokines	0.195	0.0757	no	no	no	no	no	up	DM-DS
DCA+stool	RANTES	DCA+stool+LCA+stool+RANTES	Indirect	stool_bileacids	serum_cytokines	0.195	0.0757	no	no	no	no	no	up	DM-DS
DCA+stool	RANTES	DCA+stool-GCA+stool-RANTES	Indirect	stool_bileacids	serum_cytokines	0.195	0.0757	no	no	no	no	no	up	DM-DS
Hippuric acid+urine	RANTES	Hippuric acid+urine-IL-6-RANTES	Indirect	urine_cometabolism	serum_cytokines	0.361	0.0757	no	no	no	no	no	up	DM-DS
Butyric acid+stool	RANTES	Butyric acid+stool-16:0/20:5-PC+blood-L-Isoleucine+blood-RANTES	Indirect	stool_scfa	serum_cytokines	0.102	0.0757	dn	no	no	no	no	up	DM-DS
Butyric acid+stool	RANTES	Butyric acid+stool+L-Histidine+blood+L-Isoleucine+blood-RANTES	Indirect	stool_scfa	serum_cytokines	0.102	0.0757	dn	no	no	no	no	up	DM-DS
4-hydroxybenzoic acid+stool	RANTES	4-hydroxybenzoic acid+stool+TDCA+stool-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.0757	no	dn	no	no	no	up	DM-DS
4-hydroxybenzoic acid+stool	RANTES	4-hydroxybenzoic acid+stool-LCA+stool+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.0757	no	dn	no	no	no	up	DM-DS
4-hydroxybenzoic acid+stool	RANTES	4-hydroxybenzoic acid+stool-iso-LCA+stool+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.0757	no	dn	no	no	no	up	DM-DS
Turicibacter	RANTES	Turicibacter+Desulfovibrio+Antigen processing and presentation-RANTES	Indirect	Genus	serum_cytokines	0.269	0.0757	no	no	no	no	no	up	DM-DS
GCA+blood	RANTES	GCA+blood+TDCA+blood-IP-10+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.16	0.0757	no	no	no	no	no	up	DM-DS
ACA+stool	RANTES	ACA+stool-Kynurenic acid+stool-nutriCA+stool-RANTES	Indirect	stool_bileacids	serum_cytokines	0.417	0.0757	no	no	no	no	no	up	DM-DS
CDCA+blood	RANTES	CDCA+blood-Glycine+blood+L-Asparagine+blood+L-Isoleucine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.506	0.0757	no	no	no	no	no	up	DM-DS
CDCA+blood	RANTES	CDCA+blood-Ethanolamine+blood+L-Asparagine+blood+L-Isoleucine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.506	0.0757	no	no	no	no	no	up	DM-DS
CDCA+blood	RANTES	CDCA+blood-Glycine+blood+L-Glutamine+blood+L-Isoleucine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.506	0.0757	no	no	no	no	no	up	DM-DS
CDCA+blood	RANTES	CDCA+blood-Glycine+blood+L-Histidine+blood+L-Isoleucine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.506	0.0757	no	no	no	no	no	up	DM-DS
CDCA+blood	RANTES	CDCA+blood-Ethanolamine+blood+L-Histidine+blood+L-Isoleucine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.506	0.0757	no	no	no	no	no	up	DM-DS
CDCA+blood	RANTES	CDCA+blood+UDCA+blood+Eotaxin+IL-9+RANTES	Indirect	serum_bileacids	serum_cytokines	0.506	0.0757	no	no	no	no	no	up	DM-DS
CDCA+blood	RANTES	CDCA+blood+UDCA+blood+Eotaxin+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.506	0.0757	no	no	no	no	no	up	DM-DS
CDCA+blood	RANTES	CDCA+blood+UDCA+blood+Eotaxin-IL-6-RANTES	Indirect	serum_bileacids	serum_cytokines	0.506	0.0757	no	no	no	no	no	up	DM-DS
capric acid C6+blood	RANTES	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin-IL-6-RANTES	Indirect	serum_scfa	serum_cytokines	0.433	0.0757	no	no	no	no	no	up	DM-DS
capric acid C6+blood	RANTES	capric acid C6+blood-HCA+blood-TXB2+blood+Homovanillic acid+urine-MIP-1b+RANTES	Indirect	serum_scfa	serum_cytokines	0.433	0.0757	no	no	no	no	no	up	DM-DS
capric acid C6+blood	RANTES	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin+MIP-1b+RANTES	Indirect	serum_scfa	serum_cytokines	0.433	0.0757	no	no	no	no	no	up	DM-DS
capric acid C6+blood	RANTES	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin+IL-9+RANTES	Indirect	serum_scfa	serum_cytokines	0.433	0.0757	no	no	no	no	no	up	DM-DS
Prevotella	RANTES	Prevotella-Glycolysis / Gluconeogenesis-RANTES	Indirect	Genus	serum_cytokines	0.287	0.0757	no	no	no	no	no	up	DM-DS
Prevotella	RANTES	Prevotella-Bacterial invasion of epithelial cells-RANTES	Indirect	Genus	serum_cytokines	0.287	0.0757	no	no	no	no	no	up	DM-DS
TCA+blood	RANTES	TCA+blood+TUDCA+blood-TXB2+blood+Homovanillic acid+urine-MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.339	0.0757	no	no	no	no	no	up	DM-DS
iso-DCA+blood	RANTES	iso-DCA+blood+L-Asparagine+blood+L-Isoleucine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.38	0.0757	no	no	no	no	no	up	DM-DS
iso-DCA+blood	RANTES	iso-DCA+blood-IP-10+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.38	0.0757	no	no	no	no	no	up	DM-DS
HCA+stool	RANTES	HCA+stool-HDCA+stool+LCA+stool+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	DM-DS
HCA+stool	RANTES	HCA+stool-HDCA+stool+IL-9+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	DM-DS
HCA+stool	RANTES	HCA+stool-HDCA+stool+iso-LCA+stool+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	DM-DS
Roseburia	RANTES	Roseburia+GCDCA+stool+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.495	0.0757	no	no	no	no	no	up	DM-DS
Roseburia	RANTES	Roseburia-Phenylacetic acid+stool-L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.495	0.0757	no	no	no	no	no	up	DM-DS
Roseburia	RANTES	Roseburia+16:0/16:1-PC+blood+18:0/20:3-PI+blood-RANTES	Indirect	Genus	serum_cytokines	0.495	0.0757	no	no	no	no	no	up	DM-DS
Roseburia	RANTES	Roseburia+IP-10+MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.495	0.0757	no	no	no	no	no	up	DM-DS
Roseburia	RANTES	Roseburia+GCDCA+stool+16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.495	0.0757	no	no	no	no	no	up	DM-DS
Roseburia	RANTES	Roseburia+GCDCA+stool+UDCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.495	0.0757	no	no	no	no	no	up	DM-DS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool-TDCA+stool-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-DS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+LCA+stool+RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-DS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+iso-LCA+stool+RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-DS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool-GCA+stool-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-DS
GLCA+blood	RANTES	GLCA+blood+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.319	0.0757	no	no	no	no	no	up	DM-DS
GLCA+blood	RANTES	GLCA+blood+IL-9+RANTES	Indirect	serum_bileacids	serum_cytokines	0.319	0.0757	no	no	no	no	no	up	DM-DS
GLCA+blood	RANTES	GLCA+blood+iso-LCA+blood+RANTES	Indirect	serum_bileacids	serum_cytokines	0.319	0.0757	no	no	no	no	no	up	DM-DS
L-Tryptophan+stool	RANTES	L-Tryptophan+stool+Homovanillic acid+urine-MIP-1b+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0757	no	no	no	no	no	up	DM-DS
L-Tryptophan+stool	RANTES	L-Tryptophan+stool+L-Tyrosine+stool-nutriCA+stool-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0757	no	no	no	no	no	up	DM-DS
CA+blood	RANTES	CA+blood+UDCA+blood+Eotaxin-IL-6-RANTES	Indirect	serum_bileacids	serum_cytokines	0.606	0.0757	no	no	no	no	no	up	DM-DS
CA+blood	RANTES	CA+blood+UDCA+blood+Eotaxin+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.606	0.0757	no	no	no	no	no	up	DM-DS
CA+blood	RANTES	CA+blood+TDCA+blood-IP-10+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.606	0.0757	no	no	no	no	no	up	DM-DS
CA+blood	RANTES	CA+blood+UDCA+blood+Eotaxin+IL-9+RANTES	Indirect	serum_bileacids	serum_cytokines	0.606	0.0757	no	no	no	no	no	up	DM-DS
GUDCA+stool	RANTES	GUDCA+stool+L-Homocystine+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.0085	0.0757	no	dn	no	no	no	up	DM-DS
L-Phenylalanine+stool	RANTES	L-Phenylalanine+stool+Phenylacetic acid+stool-L-Isoleucine+blood-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0757	no	no	no	no	no	up	DM-DS
L-Phenylalanine+stool	RANTES	L-Phenylalanine+stool+Homovanillic acid+urine-MIP-1b+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0757	no	no	no	no	no	up	DM-DS
L-Phenylalanine+stool	RANTES	L-Phenylalanine+stool+L-Tyrosine+stool-nutriCA+stool-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0757	no	no	no	no	no	up	DM-DS
L-Phenylalanine+stool	RANTES	L-Phenylalanine+stool-16:0/20:3-PC+blood+18:0/20:3-PI+blood-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0757	no	no	no	no	no	up	DM-DS
butyric acid C4+blood	RANTES	butyric acid C4+blood+iso-LCA+blood+RANTES	Indirect	serum_scfa	serum_cytokines	0.407	0.0757	no	no	no	no	no	up	DM-DS
GCA+stool	RANTES	GCA+stool-RANTES	Direct	stool_bileacids	serum_cytokines	0.0809	0.0757	no	no	no	no	no	up	DM-DS
Coprococcus	RANTES	Coprococcus-14:0/18:2-PC+blood-DL-methionine sulfoxide+blood+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	DM-DS
Coprococcus	RANTES	Coprococcus+Roseburia+GCDCA+stool+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	DM-DS
Coprococcus	RANTES	Coprococcus+Roseburia-Phenylacetic acid+stool-L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	DM-DS
Coprococcus	RANTES	Coprococcus-14:0/18:2-PC+blood-Creatinine+blood+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	DM-DS
Coprococcus	RANTES	Coprococcus+Roseburia+GCDCA+stool+16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	DM-DS
Coprococcus	RANTES	Coprococcus+Roseburia+16:0/16:1-PC+blood+18:0/20:3-PI+blood-RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	DM-DS
Coprococcus	RANTES	Coprococcus-14:0/18:2-PC+blood+16:0/18:3-PC+blood-18:0/20:3-PI+blood-RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	DM-DS
Coprococcus	RANTES	Coprococcus+16:0/16:0-PC+blood-GDCA+blood+iso-LCA+blood+RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	DM-DS
Coprococcus	RANTES	Coprococcus+Roseburia+GCDCA+stool+UDCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	DM-DS
Coprococcus	RANTES	Coprococcus+L-Tyrosine+blood+IP-10+MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	DM-DS
Coprococcus	RANTES	Coprococcus+Roseburia+IP-10+MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	DM-DS
Oscillospira	RANTES	Oscillospira+Platinum drug resistance+RANTES	Indirect	Genus	serum_cytokines	0.62	0.0757	no	no	no	no	no	up	DM-DS
Oscillospira	RANTES	Oscillospira+Progesterone-mediated oocyte maturation+RANTES	Indirect	Genus	serum_cytokines	0.62	0.0757	no	no	no	no	no	up	DM-DS
Oscillospira	RANTES	Oscillospira+Spliceosome+RANTES	Indirect	Genus	serum_cytokines	0.62	0.0757	no	no	no	no	no	up	DM-DS
HCA+blood	RANTES	HCA+blood+UDCA+blood+Eotaxin+IL-9+RANTES	Indirect	serum_bileacids	serum_cytokines	0.544	0.0757	no	no	no	no	no	up	DM-DS
HCA+blood	RANTES	HCA+blood-TXB2+blood+Homovanillic acid+urine-MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.544	0.0757	no	no	no	no	no	up	DM-DS
HCA+blood	RANTES	HCA+blood+UDCA+blood+Eotaxin+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.544	0.0757	no	no	no	no	no	up	DM-DS
HCA+blood	RANTES	HCA+blood+UDCA+blood+Eotaxin-IL-6-RANTES	Indirect	serum_bileacids	serum_cytokines	0.544	0.0757	no	no	no	no	no	up	DM-DS
iso-LCA+stool	RANTES	iso-LCA+stool+RANTES	Direct	stool_bileacids	serum_cytokines	0.72	0.0757	no	no	no	no	no	up	DM-DS
DCA+blood	RANTES	DCA+blood+L-Histidine+blood+L-Isoleucine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	RANTES	3-(3-Hydroxyphenyl)propanoic acid+stool-L-Homocystine+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0757	no	no	no	no	no	up	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	RANTES	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-9+RANTES"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.0757	up	up	no	no	no	up	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	RANTES	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+MIP-1b+RANTES"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.0757	up	up	no	no	no	up	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	RANTES	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-6-RANTES"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.0757	up	up	no	no	no	up	DM-DS
nutriCA+blood	RANTES	nutriCA+blood+UDCA+blood+Eotaxin-IL-6-RANTES	Indirect	serum_bileacids	serum_cytokines	0.726	0.0757	no	no	no	no	no	up	DM-DS
nutriCA+blood	RANTES	nutriCA+blood+UDCA+blood+Eotaxin+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.726	0.0757	no	no	no	no	no	up	DM-DS
nutriCA+blood	RANTES	nutriCA+blood+UDCA+blood+Eotaxin+IL-9+RANTES	Indirect	serum_bileacids	serum_cytokines	0.726	0.0757	no	no	no	no	no	up	DM-DS
4-hydroxybenzoic acid+urine	RANTES	4-hydroxybenzoic acid+urine+Homovanillic acid+urine-MIP-1b+RANTES	Indirect	urine_cometabolism	serum_cytokines	0.52	0.0757	no	no	no	no	no	up	DM-DS
Indole-3-Acetic acid+stool	RANTES	Indole-3-Acetic acid+stool-nutriCA+stool-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0757	no	no	no	no	no	up	DM-DS
Indole-3-Acetic acid+stool	RANTES	Indole-3-Acetic acid+stool-UDCA+stool-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0757	no	no	no	no	no	up	DM-DS
TCA+stool	RANTES	TCA+stool-RANTES	Direct	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-DS
HDCA+stool	RANTES	HDCA+stool+LCA+stool+RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-DS
HDCA+stool	RANTES	HDCA+stool+IL-9+RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-DS
HDCA+stool	RANTES	HDCA+stool+iso-LCA+stool+RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-DS
Lachnospira	RANTES	Lachnospira+Carbon metabolism-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-DS
Lachnospira	RANTES	Lachnospira+TCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-DS
Lachnospira	RANTES	Lachnospira-p53 signaling pathway+RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-DS
Lachnospira	RANTES	Lachnospira+Bacterial invasion of epithelial cells-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-DS
Lachnospira	RANTES	Lachnospira+Glycolysis / Gluconeogenesis-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-DS
Lachnospira	RANTES	Lachnospira-Progesterone-mediated oocyte maturation+RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-DS
Lachnospira	RANTES	Lachnospira-Platinum drug resistance+RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-DS
Lachnospira	RANTES	Lachnospira-Spliceosome+RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-DS
Lachnospira	RANTES	Lachnospira+Leukocyte transendothelial migration-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-DS
Lachnospira	RANTES	Lachnospira-ErbB signaling pathway+RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-DS
Lachnospira	RANTES	Lachnospira-Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-DS
Fusobacterium	RANTES	Fusobacterium-Intestinal immune network for IgA production-Progesterone-mediated oocyte maturation+RANTES	Indirect	Genus	serum_cytokines	0.628	0.0757	no	no	no	no	no	up	DM-DS
Fusobacterium	RANTES	Fusobacterium-Intestinal immune network for IgA production+Bacterial invasion of epithelial cells-RANTES	Indirect	Genus	serum_cytokines	0.628	0.0757	no	no	no	no	no	up	DM-DS
Fusobacterium	RANTES	Fusobacterium-Intestinal immune network for IgA production+Leishmaniasis-RANTES	Indirect	Genus	serum_cytokines	0.628	0.0757	no	no	no	no	no	up	DM-DS
Fusobacterium	RANTES	Fusobacterium-16:0/20:3-PC+blood+18:0/20:3-PI+blood-RANTES	Indirect	Genus	serum_cytokines	0.628	0.0757	no	no	no	no	no	up	DM-DS
Fusobacterium	RANTES	Fusobacterium-Intestinal immune network for IgA production+Asthma-RANTES	Indirect	Genus	serum_cytokines	0.628	0.0757	no	no	no	no	no	up	DM-DS
GCDCA+stool	RANTES	GCDCA+stool+16:1/18:2-PG+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	DM-DS
GCDCA+stool	RANTES	GCDCA+stool+L-Isoleucine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	DM-DS
GCDCA+stool	RANTES	GCDCA+stool+UDCA+stool-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	DM-DS
5-Hydroxytryptamine+stool	RANTES	5-Hydroxytryptamine+stool-UDCA+stool-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0757	dn	dn	no	no	no	up	DM-DS
5-Hydroxytryptamine+stool	RANTES	5-Hydroxytryptamine+stool-nutriCA+stool-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0757	dn	dn	no	no	no	up	DM-DS
Odoribacter	RANTES	Odoribacter+CA+stool-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-DS
Odoribacter	RANTES	Odoribacter+Glycolysis / Gluconeogenesis-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-DS
Odoribacter	RANTES	Odoribacter-iso-LCA+stool+RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-DS
Odoribacter	RANTES	Odoribacter+GCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-DS
Odoribacter	RANTES	Odoribacter+Antigen processing and presentation-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-DS
Odoribacter	RANTES	Odoribacter+Leishmaniasis-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-DS
Odoribacter	RANTES	Odoribacter-Chemical carcinogenesis - receptor activation+RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-DS
Odoribacter	RANTES	Odoribacter-LCA+stool+RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-DS
Odoribacter	RANTES	Odoribacter+Carbon metabolism-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-DS
Actinomyces	RANTES	Actinomyces+Coprococcus-14:0/18:2-PC+blood-DL-methionine sulfoxide+blood+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.621	0.0757	no	no	no	no	no	up	DM-DS
Actinomyces	RANTES	Actinomyces+Coprococcus+Roseburia+GCDCA+stool+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.621	0.0757	no	no	no	no	no	up	DM-DS
Actinomyces	RANTES	Actinomyces+Coprococcus+Roseburia-Phenylacetic acid+stool-L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.621	0.0757	no	no	no	no	no	up	DM-DS
Actinomyces	RANTES	Actinomyces+Coprococcus-14:0/18:2-PC+blood-Creatinine+blood+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.621	0.0757	no	no	no	no	no	up	DM-DS
Actinomyces	RANTES	Actinomyces+Coprococcus+Roseburia+GCDCA+stool+16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.621	0.0757	no	no	no	no	no	up	DM-DS
Actinomyces	RANTES	Actinomyces+Coprococcus+Roseburia+16:0/16:1-PC+blood+18:0/20:3-PI+blood-RANTES	Indirect	Genus	serum_cytokines	0.621	0.0757	no	no	no	no	no	up	DM-DS
Actinomyces	RANTES	Actinomyces+Coprococcus-14:0/18:2-PC+blood+16:0/18:3-PC+blood-18:0/20:3-PI+blood-RANTES	Indirect	Genus	serum_cytokines	0.621	0.0757	no	no	no	no	no	up	DM-DS
Actinomyces	RANTES	Actinomyces+Coprococcus+16:0/16:0-PC+blood-GDCA+blood+iso-LCA+blood+RANTES	Indirect	Genus	serum_cytokines	0.621	0.0757	no	no	no	no	no	up	DM-DS
Actinomyces	RANTES	Actinomyces+Coprococcus+Roseburia+GCDCA+stool+UDCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.621	0.0757	no	no	no	no	no	up	DM-DS
Actinomyces	RANTES	Actinomyces+Coprococcus+L-Tyrosine+blood+IP-10+MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.621	0.0757	no	no	no	no	no	up	DM-DS
Actinomyces	RANTES	Actinomyces+Coprococcus+Roseburia+IP-10+MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.621	0.0757	no	no	no	no	no	up	DM-DS
Isobutyric acid+stool	RANTES	Isobutyric acid+stool-nutriCA+stool-RANTES	Indirect	stool_scfa	serum_cytokines	0.408	0.0757	no	no	no	no	no	up	DM-DS
Isobutyric acid+stool	RANTES	Isobutyric acid+stool-UDCA+stool-RANTES	Indirect	stool_scfa	serum_cytokines	0.408	0.0757	no	no	no	no	no	up	DM-DS
2-hydroxyphenylacetic acid+urine	RANTES	2-hydroxyphenylacetic acid+urine+Homovanillic acid+urine-MIP-1b+RANTES	Indirect	urine_cometabolism	serum_cytokines	0.763	0.0757	no	no	no	no	no	up	DM-DS
Kynurenic acid+stool	RANTES	Kynurenic acid+stool-nutriCA+stool-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0757	dn	dn	no	no	no	up	DM-DS
Caproic acid+stool	RANTES	Caproic acid+stool-TCA+stool-RANTES	Indirect	stool_scfa	serum_cytokines	0.882	0.0757	no	no	no	no	no	up	DM-DS
Caproic acid+stool	RANTES	Caproic acid+stool-GCA+stool-RANTES	Indirect	stool_scfa	serum_cytokines	0.882	0.0757	no	no	no	no	no	up	DM-DS
Caproic acid+stool	RANTES	Caproic acid+stool-TDCA+stool-RANTES	Indirect	stool_scfa	serum_cytokines	0.882	0.0757	no	no	no	no	no	up	DM-DS
Eggerthella	RANTES	Eggerthella+nutriCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.912	0.0757	no	no	no	no	no	up	DM-DS
Eggerthella	RANTES	Eggerthella-L-Homocystine+blood+RANTES	Indirect	Genus	serum_cytokines	0.912	0.0757	no	no	no	no	no	up	DM-DS
Eggerthella	RANTES	Eggerthella-iso-LCA+stool+RANTES	Indirect	Genus	serum_cytokines	0.912	0.0757	no	no	no	no	no	up	DM-DS
Anaerotruncus	RANTES	Anaerotruncus-Ruminococcus+nutriCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.904	0.0757	no	no	no	no	no	up	DM-DS
Anaerostipes	RANTES	Anaerostipes+Spliceosome+RANTES	Indirect	Genus	serum_cytokines	0.568	0.0757	no	no	no	no	no	up	DM-DS
Anaerostipes	RANTES	Anaerostipes-IL-6-RANTES	Indirect	Genus	serum_cytokines	0.568	0.0757	no	no	no	no	no	up	DM-DS
TUDCA+stool	RANTES	TUDCA+stool+9-HODE+blood+butyric acid C4+blood+iso-LCA+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.241	0.0757	no	no	no	no	no	up	DM-DS
TUDCA+stool	RANTES	TUDCA+stool-d18:1-14:0-SM+blood+d18:1-22:1-SM+blood+iso-LCA+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.241	0.0757	no	no	no	no	no	up	DM-DS
TUDCA+stool	RANTES	TUDCA+stool-d18:1-14:0-SM+blood-L-Glutamic acid+blood+L-Isoleucine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.241	0.0757	no	no	no	no	no	up	DM-DS
TUDCA+stool	RANTES	TUDCA+stool-14:0/18:2-PC+blood-Creatinine+blood+L-Isoleucine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.241	0.0757	no	no	no	no	no	up	DM-DS
TUDCA+stool	RANTES	TUDCA+stool-14:0/18:2-PC+blood-DL-methionine sulfoxide+blood+L-Isoleucine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.241	0.0757	no	no	no	no	no	up	DM-DS
TUDCA+stool	RANTES	TUDCA+stool-d18:1-14:0-SM+blood-L-Asparagine+blood+L-Isoleucine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.241	0.0757	no	no	no	no	no	up	DM-DS
TUDCA+stool	RANTES	TUDCA+stool-d18:1-14:0-SM+blood+d18:1-14:1-SM+blood-L-Isoleucine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.241	0.0757	no	no	no	no	no	up	DM-DS
TUDCA+stool	RANTES	TUDCA+stool+9-HODE+blood-d18:1-14:1-SM+blood-L-Isoleucine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.241	0.0757	no	no	no	no	no	up	DM-DS
TUDCA+stool	RANTES	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood-18:0/20:3-PI+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.241	0.0757	no	no	no	no	no	up	DM-DS
Isovaleric acid+stool	RANTES	Isovaleric acid+stool-UDCA+stool-RANTES	Indirect	stool_scfa	serum_cytokines	0.343	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-IL-17 signaling pathway+IL-6-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Ribosome biogenesis in eukaryotes-IL-6-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Cell cycle-IL-6-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-IL-17 signaling pathway-Progesterone-mediated oocyte maturation+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Ribosome biogenesis in eukaryotes+Progesterone-mediated oocyte maturation+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Cell cycle+Progesterone-mediated oocyte maturation+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-cGMP-PKG signaling pathway-Chemical carcinogenesis - receptor activation+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Fc gamma R-mediated phagocytosis-Chemical carcinogenesis - receptor activation+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Biosynthesis of amino acids-Chemical carcinogenesis - receptor activation+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Olfactory transduction-Chemical carcinogenesis - receptor activation+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-IL-17 signaling pathway-Chemical carcinogenesis - receptor activation+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Ribosome biogenesis in eukaryotes+Chemical carcinogenesis - receptor activation+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Cell cycle+Chemical carcinogenesis - receptor activation+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Hippo signaling pathway+CDCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Ribosome biogenesis in eukaryotes+Spliceosome+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-cGMP-PKG signaling pathway+Lysosome-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Protein processing in endoplasmic reticulum-Lysosome-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Biosynthesis of amino acids+Lysosome-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-PPAR signaling pathway+Lysosome-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Nicotinate and nicotinamide metabolism+Lysosome-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+RNA degradation-Lysosome-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Arginine and proline metabolism+Lysosome-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Ribosome biogenesis in eukaryotes-Lysosome-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Cell cycle-Lysosome-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Ribosome biogenesis in eukaryotes+p53 signaling pathway+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Ribosome biogenesis in eukaryotes-Epstein-Barr virus infection-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Cell cycle-Epstein-Barr virus infection-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Ribosome biogenesis in eukaryotes-Leukocyte transendothelial migration-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Hippo signaling pathway+Leukocyte transendothelial migration-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Cell cycle-Antigen processing and presentation-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Fc gamma R-mediated phagocytosis-LCA+stool+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Biosynthesis of amino acids-LCA+stool+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Adipocytokine signaling pathway-Bacterial invasion of epithelial cells-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Thyroid hormone signaling pathway+Bacterial invasion of epithelial cells-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Hippo signaling pathway+Bacterial invasion of epithelial cells-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Adipocytokine signaling pathway-Asthma-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Thyroid hormone signaling pathway+Asthma-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Hippo signaling pathway+Asthma-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Arrhythmogenic right ventricular cardiomyopathy+TCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Hippo signaling pathway+TCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Adipocytokine signaling pathway+Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Fc epsilon RI signaling pathway+Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Hippo signaling pathway-Non-small cell lung cancer+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+IP-10+MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Biosynthesis of amino acids-MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Wnt signaling pathway-16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Protein processing in endoplasmic reticulum-16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Fc epsilon RI signaling pathway+16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Epithelial cell signaling in Helicobacter pylori infection+16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+RNA degradation-16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-IL-17 signaling pathway+16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Cell cycle-16:1/18:2-PG+blood-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Adipocytokine signaling pathway+Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Nicotinate and nicotinamide metabolism+Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Fc epsilon RI signaling pathway+Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Arginine and proline metabolism+Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-GABAergic synapse+Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella+Hippo signaling pathway-Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Biosynthesis of amino acids+GCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Paraprevotella	RANTES	Paraprevotella-Peroxisome+GCA+stool-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-DS
Homovanillic acid+urine	RANTES	Homovanillic acid+urine-MIP-1b+RANTES	Indirect	urine_cometabolism	serum_cytokines	0.45	0.0757	no	no	no	no	no	up	DM-DS
TDCA+blood	RANTES	TDCA+blood-IP-10+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.155	0.0757	no	up	no	no	no	up	DM-DS
iso-LCA+blood	RANTES	iso-LCA+blood+RANTES	Direct	serum_bileacids	serum_cytokines	0.507	0.0757	no	no	no	no	no	up	DM-DS
¦Ø-MCA+stool	RANTES	¦Ø-MCA+stool+CDCA+stool-RANTES	Indirect	stool_bileacids	serum_cytokines	0.919	0.0757	no	no	no	no	no	up	DM-DS
Phenylacetic acid+stool	RANTES	Phenylacetic acid+stool-L-Isoleucine+blood-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0757	no	no	no	no	no	up	DM-DS
Gemmiger	RANTES	Gemmiger+Pathways in cancer+RANTES	Indirect	Genus	serum_cytokines	0.595	0.0757	no	no	no	no	no	up	DM-DS
Gemmiger	RANTES	Gemmiger+ErbB signaling pathway+RANTES	Indirect	Genus	serum_cytokines	0.595	0.0757	no	no	no	no	no	up	DM-DS
GDCA+stool	RANTES	GDCA+stool+UDCA+stool-RANTES	Indirect	stool_bileacids	serum_cytokines	0.656	0.0757	no	no	no	no	no	up	DM-DS
GDCA+stool	RANTES	GDCA+stool+L-Isoleucine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.656	0.0757	no	no	no	no	no	up	DM-DS
Methanobrevibacter	RANTES	Methanobrevibacter-Alcoholism-MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.629	0.0757	no	no	no	no	no	up	DM-DS
Methanobrevibacter	RANTES	Methanobrevibacter-Cystine+blood+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.629	0.0757	no	no	no	no	no	up	DM-DS
Methanobrevibacter	RANTES	Methanobrevibacter-Alcoholism-IL-9+RANTES	Indirect	Genus	serum_cytokines	0.629	0.0757	no	no	no	no	no	up	DM-DS
L-Tyrosine+stool	RANTES	L-Tyrosine+stool-nutriCA+stool-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0757	no	no	no	no	no	up	DM-DS
CDCA+stool	RANTES	CDCA+stool-RANTES	Direct	stool_bileacids	serum_cytokines	0.663	0.0757	no	no	no	no	no	up	DM-DS
CA+stool	RANTES	CA+stool-RANTES	Direct	stool_bileacids	serum_cytokines	0.827	0.0757	no	no	no	no	no	up	DM-DS
HDCA+blood	RANTES	HDCA+blood+L-Homocystine+blood+RANTES	Indirect	serum_bileacids	serum_cytokines	0.483	0.0757	no	no	no	no	no	up	DM-DS
HDCA+blood	RANTES	HDCA+blood+iso-LCA+blood+RANTES	Indirect	serum_bileacids	serum_cytokines	0.483	0.0757	no	no	no	no	no	up	DM-DS
UDCA+stool	RANTES	UDCA+stool-RANTES	Direct	stool_bileacids	serum_cytokines	0.266	0.0757	no	no	no	no	no	up	DM-DS
TDCA+stool	RANTES	TDCA+stool-RANTES	Direct	stool_bileacids	serum_cytokines	0.963	0.0757	no	no	no	no	no	up	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	RANTES	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2-RANTES	Indirect	urine_cometabolism	serum_cytokines	0.973	0.0757	no	no	no	no	no	up	DM-DS
Desulfovibrio	RANTES	Desulfovibrio+Antigen processing and presentation-RANTES	Indirect	Genus	serum_cytokines	0.27	0.0757	no	no	no	no	no	up	DM-DS
nutriCA+stool	RANTES	nutriCA+stool-RANTES	Direct	stool_bileacids	serum_cytokines	0.481	0.0757	no	no	no	no	no	up	DM-DS
Bilophila	RANTES	Bilophila+Desulfovibrio+Antigen processing and presentation-RANTES	Indirect	Genus	serum_cytokines	0.528	0.0757	no	no	no	no	no	up	DM-DS
GDCA+blood	RANTES	GDCA+blood+iso-LCA+blood+RANTES	Indirect	serum_bileacids	serum_cytokines	0.632	0.0757	no	no	no	no	no	up	DM-DS
P-hydroxyhippuric acid+urine	RANTES	P-hydroxyhippuric acid+urine+Eotaxin+IL-9+RANTES	Indirect	urine_cometabolism	serum_cytokines	0.436	0.0757	no	no	no	no	no	up	DM-DS
P-hydroxyhippuric acid+urine	RANTES	P-hydroxyhippuric acid+urine+Eotaxin-IL-6-RANTES	Indirect	urine_cometabolism	serum_cytokines	0.436	0.0757	no	no	no	no	no	up	DM-DS
P-hydroxyhippuric acid+urine	RANTES	P-hydroxyhippuric acid+urine+Eotaxin+MIP-1b+RANTES	Indirect	urine_cometabolism	serum_cytokines	0.436	0.0757	no	no	no	no	no	up	DM-DS
acetic acid C2+blood	RANTES	acetic acid C2+blood+d18:1-22:1-SM+blood+iso-LCA+blood+RANTES	Indirect	serum_scfa	serum_cytokines	0.000193	0.0757	up	dn	no	no	no	up	DM-DS
isovaleric acid iso-C5+blood	RANTES	isovaleric acid iso-C5+blood-L-Phenylalanine+blood+L-Tyrosine+blood+IP-10+MIP-1b+RANTES	Indirect	serum_scfa	serum_cytokines	0.117	0.0757	no	no	no	no	no	up	DM-DS
isovaleric acid iso-C5+blood	RANTES	isovaleric acid iso-C5+blood+n3+blood+TXB2+blood+Homovanillic acid+urine-MIP-1b+RANTES	Indirect	serum_scfa	serum_cytokines	0.117	0.0757	no	no	no	no	no	up	DM-DS
Clostridium	RANTES	Clostridium-RANTES	Direct	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-DS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-UDCA+stool-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-DS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood+RANTES	Direct	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-DS
Butyricicoccus	RANTES	"Butyricicoccus+12,13-EPOME+blood+18:1/18:1-PE+blood-IL-9+RANTES"	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	DM-DS
Butyricicoccus	RANTES	"Butyricicoccus+12,13-EPOME+blood+16:0/18:1-PE+blood+18:0/20:3-PI+blood-RANTES"	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	DM-DS
Butyricicoccus	RANTES	Butyricicoccus-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	DM-DS
Butyricicoccus	RANTES	"Butyricicoccus+12,13-EPOME+blood-HDCA+blood+L-Homocystine+blood+RANTES"	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	DM-DS
Butyricicoccus	RANTES	"Butyricicoccus+12,13-EPOME+blood-HDCA+blood+iso-LCA+blood+RANTES"	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	DM-DS
Butyricicoccus	RANTES	"Butyricicoccus+12,13-EPOME+blood-20:0-LPC+blood+iso-LCA+blood+RANTES"	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	DM-DS
Butyricicoccus	RANTES	Butyricicoccus-18:2/20:4-PC+blood+20:0-LPC+blood+iso-LCA+blood+RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	DM-DS
Butyricicoccus	RANTES	"Butyricicoccus+12,13-EPOME+blood-d18:1-22:1-SM+blood+iso-LCA+blood+RANTES"	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	DM-DS
Blautia	IL-1ra	Blautia-Cocaine addiction-IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	DM-DS
Blautia	IL-1ra	Blautia+UDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	DM-DS
Blautia	IL-1ra	Blautia-Thyroid hormone synthesis-IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	DM-DS
Blautia	IL-1ra	Blautia-TDCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	DM-DS
Blautia	IL-1ra	Blautia+CDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	DM-DS
Blautia	IL-1ra	Blautia-Calcium signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	DM-DS
Blautia	IL-1ra	Blautia+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	DM-DS
Blautia	IL-1ra	Blautia+Longevity regulating pathway - multiple species+IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	DM-DS
Parabacteroides	IL-1ra	Parabacteroides-16:0/18:2-PI+blood+IL-1ra	Indirect	Genus	serum_cytokines	4.19E-05	0.0288	no	up	up	no	up	up	DM-DS
Parabacteroides	IL-1ra	Parabacteroides-L-Alanine+blood-IL-1ra	Indirect	Genus	serum_cytokines	4.19E-05	0.0288	no	up	up	no	up	up	DM-DS
Dorea	IL-1ra	Dorea+UDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.00362	0.0288	up	no	dn	no	up	up	DM-DS
Dorea	IL-1ra	Dorea+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.00362	0.0288	up	no	dn	no	up	up	DM-DS
Dorea	IL-1ra	Dorea+Carbon metabolism+IL-1ra	Indirect	Genus	serum_cytokines	0.00362	0.0288	up	no	dn	no	up	up	DM-DS
Dorea	IL-1ra	Dorea+CDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.00362	0.0288	up	no	dn	no	up	up	DM-DS
Faecalibacterium	IL-1ra	Faecalibacterium+L-Alanine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.0039	0.0288	no	dn	dn	no	up	up	DM-DS
Bacteroides	IL-1ra	"Bacteroides-Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.000267	0.0288	dn	dn	up	no	up	up	DM-DS
Bacteroides	IL-1ra	Bacteroides+Longevity regulating pathway - multiple species+IL-1ra	Indirect	Genus	serum_cytokines	0.000267	0.0288	dn	dn	up	no	up	up	DM-DS
Bacteroides	IL-1ra	Bacteroides-Long-term depression-IL-1ra	Indirect	Genus	serum_cytokines	0.000267	0.0288	dn	dn	up	no	up	up	DM-DS
Propionic acid+stool	IL-1ra	Propionic acid+stool+P-hydroxyhippuric acid+urine-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.0436	0.0288	dn	no	up	no	up	up	DM-DS
[Ruminococcus]	IL-1ra	[Ruminococcus]-18:2/20:4-PC+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.0679	0.0288	no	no	dn	no	up	up	DM-DS
[Ruminococcus]	IL-1ra	[Ruminococcus]+16:0/18:2-PI+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.0679	0.0288	no	no	dn	no	up	up	DM-DS
GUDCA+blood	IL-1ra	GUDCA+blood+HCA+blood-L-Threonine+blood-SFA+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0288	no	no	dn	no	up	up	DM-DS
Acetic acid+stool	IL-1ra	Acetic acid+stool+P-hydroxyhippuric acid+urine-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.0656	0.0288	dn	no	no	no	up	up	DM-DS
Alistipes	IL-1ra	Alistipes+18:2/20:4-PC+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.0114	0.0288	no	up	no	no	up	up	DM-DS
Butyricimonas	IL-1ra	Butyricimonas-iso-DCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.17	0.0288	no	no	no	no	up	up	DM-DS
Collinsella	IL-1ra	Collinsella-GnRH signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.128	0.0288	no	no	no	no	up	up	DM-DS
Collinsella	IL-1ra	Collinsella-Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.128	0.0288	no	no	no	no	up	up	DM-DS
Collinsella	IL-1ra	Collinsella-18:2/20:4-PC+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.128	0.0288	no	no	no	no	up	up	DM-DS
Sarcina	IL-1ra	Sarcina-Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.0703	0.0288	no	no	no	no	up	up	DM-DS
Sarcina	IL-1ra	Sarcina-GnRH signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.0703	0.0288	no	no	no	no	up	up	DM-DS
Sarcina	IL-1ra	Sarcina-Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.0703	0.0288	no	no	no	no	up	up	DM-DS
Methanosphaera	IL-1ra	Methanosphaera-Roseburia+16:0/18:2-PI+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.0703	0.0288	no	no	no	no	up	up	DM-DS
iso-DCA+stool	IL-1ra	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.155	0.0288	no	no	no	no	up	up	DM-DS
LCA+stool	IL-1ra	LCA+stool-IL-1ra	Direct	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	DM-DS
Akkermansia	IL-1ra	Akkermansia+P-hydroxyhippuric acid+urine-IL-1ra	Indirect	Genus	serum_cytokines	0.23	0.0288	no	no	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-12-HEPE+blood-L-Alanine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-Glutamatergic synapse+Cortisol synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Leukocyte transendothelial migration-Cortisol synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-Glutamatergic synapse+GnRH signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	"Bifidobacterium-Glutamatergic synapse+Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	"Bifidobacterium-Autophagy - animal+Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	"Bifidobacterium+HIF-1 signaling pathway-Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	"Bifidobacterium+Proteasome-Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	"Bifidobacterium-FoxO signaling pathway+Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	"Bifidobacterium+Tight junction-Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	"Bifidobacterium+Glycolysis / Gluconeogenesis-Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	"Bifidobacterium+Focal adhesion-Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	"Bifidobacterium+Hippo signaling pathway-Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	"Bifidobacterium+Leukocyte transendothelial migration-Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	"Bifidobacterium+Adherens junction-Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-Autophagy - animal-Adrenergic signaling in cardiomyocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+HIF-1 signaling pathway+Adrenergic signaling in cardiomyocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-FoxO signaling pathway-Adrenergic signaling in cardiomyocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Thyroid hormone signaling pathway+Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-Autophagy - animal-Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-FoxO signaling pathway-Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Focal adhesion+Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Hippo signaling pathway+Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Adherens junction+Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-16:0+blood+20:3/16:0-PC+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Thyroid hormone signaling pathway+Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-Autophagy - animal-Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+HIF-1 signaling pathway+Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-GABAergic synapse-Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Hippo signaling pathway+Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Arrhythmogenic right ventricular cardiomyopathy+18:0/18:0-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Hippo signaling pathway+18:0/18:0-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Leukocyte transendothelial migration-Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-Autophagy - animal-Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+HIF-1 signaling pathway+Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-GABAergic synapse-Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-FoxO signaling pathway-Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Focal adhesion+Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Hippo signaling pathway+Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Adherens junction+Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Leukocyte transendothelial migration-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Thyroid hormone signaling pathway+Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Gastric acid secretion+Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-Autophagy - animal-Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-FoxO signaling pathway-Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Tight junction+Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Focal adhesion+Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Hippo signaling pathway+Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Adherens junction+Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-Glutamatergic synapse+Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Proteasome-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Tight junction-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Bacterial invasion of epithelial cells-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Glycolysis / Gluconeogenesis-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Leukocyte transendothelial migration-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Leukocyte transendothelial migration+Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-Breast cancer+12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Leukocyte transendothelial migration-12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-Glutamatergic synapse+Regulation of lipolysis in adipocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Proteasome-Regulation of lipolysis in adipocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-Glutamatergic synapse-UDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Proteasome+UDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+CA+stool+UDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	"Bifidobacterium+HIF-1 signaling pathway+Parathyroid hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	"Bifidobacterium-FoxO signaling pathway-Parathyroid hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-SFA+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-18:0/20:4-PI+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-16:0+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-Glutamatergic synapse+Long-term depression-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Proteasome-Long-term depression-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Glycolysis / Gluconeogenesis-Long-term depression-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Thyroid hormone signaling pathway+18:0/18:1-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Arrhythmogenic right ventricular cardiomyopathy+18:0/18:1-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Hippo signaling pathway+18:0/18:1-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Adherens junction+18:0/18:1-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Proteasome-Gap junction-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Glycolysis / Gluconeogenesis-Gap junction-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Thyroid hormone signaling pathway+Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-Autophagy - animal-Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-GABAergic synapse-Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Proteasome-GDCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Hippo signaling pathway-GDCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Proteasome-Hypotaurine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Proteasome-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Tight junction-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Bacterial invasion of epithelial cells-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+CA+stool-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Leukocyte transendothelial migration-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Proteasome-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Tight junction-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Bacterial invasion of epithelial cells-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+CA+stool-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Leukocyte transendothelial migration-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Thyroid hormone signaling pathway+Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-Autophagy - animal-Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-FoxO signaling pathway-Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Hippo signaling pathway+Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Adherens junction+Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-Glutamatergic synapse-CDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Proteasome+CDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+CA+stool+CDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Hippo signaling pathway+CDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-FoxO signaling pathway-16:0/18:2-PI+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Tight junction+16:0/18:2-PI+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Leukocyte transendothelial migration+16:0/18:2-PI+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-18:0/20:4-PI+blood+18:0/22:6-PA+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-Glutamatergic synapse+Cocaine addiction-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium-Glutamatergic synapse-GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Proteasome+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Glycolysis / Gluconeogenesis+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+CA+stool+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Bifidobacterium	IL-1ra	Bifidobacterium+Glycolysis / Gluconeogenesis+Carbon metabolism+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-DS
Ruminococcus	IL-1ra	Ruminococcus+18:0/18:0-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	DM-DS
GCDCA+blood	IL-1ra	GCDCA+blood+L-Alanine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.31	0.0288	no	no	no	no	up	up	DM-DS
ACA+blood	IL-1ra	ACA+blood+EPA+blood+isovaleric acid iso-C5+blood+PUFA+blood+SFA+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.338	0.0288	no	no	no	no	up	up	DM-DS
ACA+blood	IL-1ra	ACA+blood-decanoic acid C10+blood-isovaleric acid iso-C5+blood+PUFA+blood+SFA+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.338	0.0288	no	no	no	no	up	up	DM-DS
ACA+blood	IL-1ra	ACA+blood+EPA+blood+n3+blood+PUFA+blood+SFA+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.338	0.0288	no	no	no	no	up	up	DM-DS
ACA+blood	IL-1ra	ACA+blood-decanoic acid C10+blood-n3+blood+PUFA+blood+SFA+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.338	0.0288	no	no	no	no	up	up	DM-DS
DCA+stool	IL-1ra	DCA+stool+iso-LCA+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-DS
DCA+stool	IL-1ra	DCA+stool+HDCA+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-DS
DCA+stool	IL-1ra	DCA+stool+LCA+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-DS
DCA+stool	IL-1ra	DCA+stool-GCA+stool+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-DS
Butyric acid+stool	IL-1ra	Butyric acid+stool+P-hydroxyhippuric acid+urine-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.102	0.0288	dn	no	no	no	up	up	DM-DS
4-hydroxybenzoic acid+stool	IL-1ra	4-hydroxybenzoic acid+stool-LCA+stool-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.0288	no	dn	no	no	up	up	DM-DS
4-hydroxybenzoic acid+stool	IL-1ra	4-hydroxybenzoic acid+stool-iso-LCA+stool-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.0288	no	dn	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Antigen processing and presentation-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Antigen processing and presentation-12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Antigen processing and presentation-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+UDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Antigen processing and presentation+UDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+UDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Antigen processing and presentation+Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Antigen processing and presentation-Regulation of lipolysis in adipocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Antigen processing and presentation-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Antigen processing and presentation-Cocaine addiction-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Antigen processing and presentation+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Antigen processing and presentation-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Antigen processing and presentation-Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Antigen processing and presentation-Cortisol synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Antigen processing and presentation-Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	Turicibacter+Desulfovibrio+Antigen processing and presentation-GnRH signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
Turicibacter	IL-1ra	"Turicibacter+Desulfovibrio+Antigen processing and presentation-Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.269	0.0288	no	no	no	no	up	up	DM-DS
GCA+blood	IL-1ra	GCA+blood+TDCA+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.16	0.0288	no	no	no	no	up	up	DM-DS
ACA+stool	IL-1ra	ACA+stool-L-Phenylalanine+stool-SFA+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.417	0.0288	no	no	no	no	up	up	DM-DS
ACA+stool	IL-1ra	ACA+stool-L-Phenylalanine+stool-24:0+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.417	0.0288	no	no	no	no	up	up	DM-DS
ACA+stool	IL-1ra	ACA+stool-Kynurenic acid+stool-nutriCA+stool+18:0/18:0-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.417	0.0288	no	no	no	no	up	up	DM-DS
ACA+stool	IL-1ra	ACA+stool-L-Phenylalanine+stool-16:0/20:3-PC+blood+18:0/18:0-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.417	0.0288	no	no	no	no	up	up	DM-DS
ACA+stool	IL-1ra	ACA+stool-Kynurenic acid+stool-nutriCA+stool+18:0/18:1-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.417	0.0288	no	no	no	no	up	up	DM-DS
ACA+stool	IL-1ra	ACA+stool-L-Phenylalanine+stool-16:0/20:3-PC+blood+18:0/18:1-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.417	0.0288	no	no	no	no	up	up	DM-DS
ACA+stool	IL-1ra	ACA+stool-L-Tryptophan+stool+8-HETE+blood+Hypotaurine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.417	0.0288	no	no	no	no	up	up	DM-DS
ACA+stool	IL-1ra	ACA+stool-L-Phenylalanine+stool+8-HETE+blood+Hypotaurine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.417	0.0288	no	no	no	no	up	up	DM-DS
ACA+stool	IL-1ra	ACA+stool-Kynurenic acid+stool-nutriCA+stool+18:0/22:6-PA+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.417	0.0288	no	no	no	no	up	up	DM-DS
ACA+stool	IL-1ra	ACA+stool-L-Tryptophan+stool+L-Tyrosine+stool-18:2/20:4-PC+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.417	0.0288	no	no	no	no	up	up	DM-DS
ACA+stool	IL-1ra	ACA+stool-L-Phenylalanine+stool+L-Tyrosine+stool-18:2/20:4-PC+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.417	0.0288	no	no	no	no	up	up	DM-DS
ACA+stool	IL-1ra	ACA+stool-Kynurenic acid+stool+L-Tyrosine+stool-18:2/20:4-PC+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.417	0.0288	no	no	no	no	up	up	DM-DS
ACA+stool	IL-1ra	ACA+stool-Kynurenic acid+stool-nutriCA+stool+UDCA+stool+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.417	0.0288	no	no	no	no	up	up	DM-DS
CDCA+blood	IL-1ra	CDCA+blood+GCDCA+blood+L-Alanine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.506	0.0288	no	no	no	no	up	up	DM-DS
CDCA+blood	IL-1ra	CDCA+blood-Glycine+blood+Hypotaurine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.506	0.0288	no	no	no	no	up	up	DM-DS
CDCA+blood	IL-1ra	CDCA+blood-Ethanolamine+blood+Hypotaurine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.506	0.0288	no	no	no	no	up	up	DM-DS
capric acid C6+blood	IL-1ra	capric acid C6+blood-HCA+blood-L-Threonine+blood-SFA+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.433	0.0288	no	no	no	no	up	up	DM-DS
Prevotella	IL-1ra	Prevotella+TDCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.287	0.0288	no	no	no	no	up	up	DM-DS
Prevotella	IL-1ra	Prevotella+GDCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.287	0.0288	no	no	no	no	up	up	DM-DS
Prevotella	IL-1ra	"Prevotella+Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.287	0.0288	no	no	no	no	up	up	DM-DS
Prevotella	IL-1ra	Prevotella+Endocrine resistance-IL-1ra	Indirect	Genus	serum_cytokines	0.287	0.0288	no	no	no	no	up	up	DM-DS
iso-DCA+blood	IL-1ra	iso-DCA+blood-IL-1ra	Direct	serum_bileacids	serum_cytokines	0.38	0.0288	no	no	no	no	up	up	DM-DS
HCA+stool	IL-1ra	HCA+stool-HDCA+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.155	0.0288	no	no	no	no	up	up	DM-DS
Roseburia	IL-1ra	Roseburia+16:0/18:2-PI+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.495	0.0288	no	no	no	no	up	up	DM-DS
12-ketoDCA+stool	IL-1ra	12-ketoDCA+stool-IL-1ra	Direct	stool_bileacids	serum_cytokines	0.505	0.0288	no	no	no	no	up	up	DM-DS
GLCA+blood	IL-1ra	GLCA+blood+TDCA+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.319	0.0288	no	no	no	no	up	up	DM-DS
L-Tryptophan+stool	IL-1ra	L-Tryptophan+stool+L-Tyrosine+stool-18:2/20:4-PC+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0288	no	no	no	no	up	up	DM-DS
L-Tryptophan+stool	IL-1ra	L-Tryptophan+stool+8-HETE+blood+Hypotaurine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0288	no	no	no	no	up	up	DM-DS
CA+blood	IL-1ra	CA+blood+TDCA+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.606	0.0288	no	no	no	no	up	up	DM-DS
GUDCA+stool	IL-1ra	GUDCA+stool+12-HEPE+blood-L-Alanine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.0085	0.0288	no	dn	no	no	up	up	DM-DS
L-Phenylalanine+stool	IL-1ra	L-Phenylalanine+stool-16:0/20:3-PC+blood+18:0/18:0-PC+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0288	no	no	no	no	up	up	DM-DS
L-Phenylalanine+stool	IL-1ra	L-Phenylalanine+stool+L-Tyrosine+stool-18:2/20:4-PC+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0288	no	no	no	no	up	up	DM-DS
L-Phenylalanine+stool	IL-1ra	L-Phenylalanine+stool-24:0+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0288	no	no	no	no	up	up	DM-DS
L-Phenylalanine+stool	IL-1ra	L-Phenylalanine+stool-SFA+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0288	no	no	no	no	up	up	DM-DS
L-Phenylalanine+stool	IL-1ra	L-Phenylalanine+stool+8-HETE+blood+Hypotaurine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0288	no	no	no	no	up	up	DM-DS
L-Phenylalanine+stool	IL-1ra	L-Phenylalanine+stool-16:0/20:3-PC+blood+18:0/18:1-PC+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0288	no	no	no	no	up	up	DM-DS
GCA+stool	IL-1ra	GCA+stool+IL-1ra	Direct	stool_bileacids	serum_cytokines	0.0809	0.0288	no	no	no	no	up	up	DM-DS
Coprococcus	IL-1ra	Coprococcus+Roseburia+16:0/18:2-PI+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-DS
Coprococcus	IL-1ra	Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine-IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-DS
Coprococcus	IL-1ra	Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-DS
Coprococcus	IL-1ra	Coprococcus+16:0/16:0-PC+blood+18:0/22:6-PA+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-DS
Coprococcus	IL-1ra	Coprococcus+16:0/16:0-PC+blood-GDCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-DS
Oscillospira	IL-1ra	Oscillospira-Calcium signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.62	0.0288	no	no	no	no	up	up	DM-DS
Oscillospira	IL-1ra	Oscillospira-Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.62	0.0288	no	no	no	no	up	up	DM-DS
Oscillospira	IL-1ra	Oscillospira-Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.62	0.0288	no	no	no	no	up	up	DM-DS
Oscillospira	IL-1ra	Oscillospira-Thyroid hormone synthesis-IL-1ra	Indirect	Genus	serum_cytokines	0.62	0.0288	no	no	no	no	up	up	DM-DS
Oscillospira	IL-1ra	Oscillospira-Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.62	0.0288	no	no	no	no	up	up	DM-DS
Oscillospira	IL-1ra	Oscillospira-Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.62	0.0288	no	no	no	no	up	up	DM-DS
Oscillospira	IL-1ra	"Oscillospira-Parathyroid hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.62	0.0288	no	no	no	no	up	up	DM-DS
HCA+blood	IL-1ra	HCA+blood-L-Threonine+blood-SFA+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.544	0.0288	no	no	no	no	up	up	DM-DS
iso-LCA+stool	IL-1ra	iso-LCA+stool-IL-1ra	Direct	stool_bileacids	serum_cytokines	0.72	0.0288	no	no	no	no	up	up	DM-DS
DCA+blood	IL-1ra	DCA+blood+L-Histidine+blood-n3+blood+PUFA+blood+SFA+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.122	0.0288	no	no	no	no	up	up	DM-DS
DCA+blood	IL-1ra	DCA+blood+L-Histidine+blood+L-Lysine+blood+L-Threonine+blood-SFA+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.122	0.0288	no	no	no	no	up	up	DM-DS
DCA+blood	IL-1ra	DCA+blood+L-Histidine+blood+L-Methionine+blood+L-Threonine+blood-SFA+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.122	0.0288	no	no	no	no	up	up	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1ra	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Alanine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0288	no	no	no	no	up	up	DM-DS
Indole-3-Acetic acid+stool	IL-1ra	Indole-3-Acetic acid+stool-UDCA+stool+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0288	no	no	no	no	up	up	DM-DS
TCA+stool	IL-1ra	TCA+stool+16:0/18:2-PI+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.458	0.0288	no	no	no	no	up	up	DM-DS
HDCA+stool	IL-1ra	HDCA+stool-IL-1ra	Direct	stool_bileacids	serum_cytokines	0.176	0.0288	no	no	no	no	up	up	DM-DS
Lachnospira	IL-1ra	Lachnospira+Carbon metabolism+IL-1ra	Indirect	Genus	serum_cytokines	0.279	0.0288	no	no	no	no	up	up	DM-DS
Fusobacterium	IL-1ra	Fusobacterium-18:0/18:0-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.628	0.0288	no	no	no	no	up	up	DM-DS
Fusobacterium	IL-1ra	Fusobacterium-18:0/18:1-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.628	0.0288	no	no	no	no	up	up	DM-DS
GCDCA+stool	IL-1ra	GCDCA+stool+UDCA+stool+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0288	no	dn	no	no	up	up	DM-DS
5-Hydroxytryptamine+stool	IL-1ra	5-Hydroxytryptamine+stool-UDCA+stool+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0288	dn	dn	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter-Thyroid hormone synthesis-IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter+Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter-12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter-Cocaine addiction-IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter-Regulation of lipolysis in adipocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter-Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter-GnRH signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter-Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter-Cortisol synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	"Odoribacter-Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter-Gap junction-IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter+16:0/20:4-PI+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter-Endocrine resistance-IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter-Long-term depression-IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter+Carbon metabolism+IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Odoribacter	IL-1ra	Odoribacter+Longevity regulating pathway - multiple species+IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-DS
Actinomyces	IL-1ra	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.621	0.0288	no	no	no	no	up	up	DM-DS
Actinomyces	IL-1ra	Actinomyces+Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine-IL-1ra	Indirect	Genus	serum_cytokines	0.621	0.0288	no	no	no	no	up	up	DM-DS
Actinomyces	IL-1ra	Actinomyces+Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	Genus	serum_cytokines	0.621	0.0288	no	no	no	no	up	up	DM-DS
Actinomyces	IL-1ra	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:0/22:6-PA+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.621	0.0288	no	no	no	no	up	up	DM-DS
Actinomyces	IL-1ra	Actinomyces+Coprococcus+16:0/16:0-PC+blood-GDCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.621	0.0288	no	no	no	no	up	up	DM-DS
Isobutyric acid+stool	IL-1ra	Isobutyric acid+stool-UDCA+stool+IL-1ra	Indirect	stool_scfa	serum_cytokines	0.408	0.0288	no	no	no	no	up	up	DM-DS
Kynurenic acid+stool	IL-1ra	Kynurenic acid+stool-nutriCA+stool+18:0/18:0-PC+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0288	dn	dn	no	no	up	up	DM-DS
Kynurenic acid+stool	IL-1ra	Kynurenic acid+stool-nutriCA+stool+18:0/22:6-PA+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0288	dn	dn	no	no	up	up	DM-DS
Kynurenic acid+stool	IL-1ra	Kynurenic acid+stool-nutriCA+stool+UDCA+stool+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0288	dn	dn	no	no	up	up	DM-DS
Kynurenic acid+stool	IL-1ra	Kynurenic acid+stool+L-Tyrosine+stool-18:2/20:4-PC+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0288	dn	dn	no	no	up	up	DM-DS
Kynurenic acid+stool	IL-1ra	Kynurenic acid+stool-nutriCA+stool+18:0/18:1-PC+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0288	dn	dn	no	no	up	up	DM-DS
Caproic acid+stool	IL-1ra	Caproic acid+stool-GCA+stool+IL-1ra	Indirect	stool_scfa	serum_cytokines	0.882	0.0288	no	no	no	no	up	up	DM-DS
Eggerthella	IL-1ra	Eggerthella-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.912	0.0288	no	no	no	no	up	up	DM-DS
Anaerotruncus	IL-1ra	Anaerotruncus-Ruminococcus+18:0/18:0-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.904	0.0288	no	no	no	no	up	up	DM-DS
Anaerostipes	IL-1ra	Anaerostipes-TDCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.568	0.0288	no	no	no	no	up	up	DM-DS
Anaerostipes	IL-1ra	Anaerostipes-GDCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.568	0.0288	no	no	no	no	up	up	DM-DS
TUDCA+stool	IL-1ra	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood+TDCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.241	0.0288	no	no	no	no	up	up	DM-DS
TUDCA+stool	IL-1ra	TUDCA+stool-14:0/18:2-PC+blood-Creatinine+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.241	0.0288	no	no	no	no	up	up	DM-DS
TUDCA+stool	IL-1ra	TUDCA+stool-14:0/18:2-PC+blood+24:0+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.241	0.0288	no	no	no	no	up	up	DM-DS
TUDCA+stool	IL-1ra	TUDCA+stool-14:0/18:2-PC+blood+14:0/20:4-PC+blood+18:2/20:4-PC+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.241	0.0288	no	no	no	no	up	up	DM-DS
TUDCA+stool	IL-1ra	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+Hypotaurine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.241	0.0288	no	no	no	no	up	up	DM-DS
TUDCA+stool	IL-1ra	TUDCA+stool-d18:1-14:0-SM+blood-Ethanolamine+blood+Hypotaurine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.241	0.0288	no	no	no	no	up	up	DM-DS
TUDCA+stool	IL-1ra	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:3/16:0-PC+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.241	0.0288	no	no	no	no	up	up	DM-DS
Isovaleric acid+stool	IL-1ra	Isovaleric acid+stool-UDCA+stool+IL-1ra	Indirect	stool_scfa	serum_cytokines	0.343	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Wnt signaling pathway+Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway-Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Protein processing in endoplasmic reticulum+Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc gamma R-mediated phagocytosis-Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Inflammatory mediator regulation of TRP channels+Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway-Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Nicotinate and nicotinamide metabolism-Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc epsilon RI signaling pathway-Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome-Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Olfactory transduction-Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Thyroid hormone signaling pathway+Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+RNA degradation+Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-IL-17 signaling pathway-Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Arginine and proline metabolism-Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Hippo signaling pathway+Vasopressin-regulated water reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Epithelial cell signaling in Helicobacter pylori infection+18:0/18:2-PI+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway-Adrenergic signaling in cardiomyocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Protein processing in endoplasmic reticulum+Adrenergic signaling in cardiomyocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-Adrenergic signaling in cardiomyocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway-Adrenergic signaling in cardiomyocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Nicotinate and nicotinamide metabolism-Adrenergic signaling in cardiomyocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome-Adrenergic signaling in cardiomyocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+RNA degradation+Adrenergic signaling in cardiomyocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Arginine and proline metabolism-Adrenergic signaling in cardiomyocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Cell cycle+Adrenergic signaling in cardiomyocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Arrhythmogenic right ventricular cardiomyopathy+18:0/18:0-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Hippo signaling pathway+18:0/18:0-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome+Longevity regulating pathway - multiple species+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway-Cocaine addiction-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc gamma R-mediated phagocytosis-Cocaine addiction-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-Cocaine addiction-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Inflammatory mediator regulation of TRP channels+Cocaine addiction-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome-Cocaine addiction-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Olfactory transduction-Cocaine addiction-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc gamma R-mediated phagocytosis-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Olfactory transduction-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-IL-17 signaling pathway-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Ribosome biogenesis in eukaryotes+Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Cell cycle+Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Hippo signaling pathway+CDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway-GnRH signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc gamma R-mediated phagocytosis-GnRH signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-GnRH signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Inflammatory mediator regulation of TRP channels+GnRH signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway-GnRH signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome-GnRH signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Olfactory transduction-GnRH signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-IL-17 signaling pathway-GnRH signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Wnt signaling pathway+Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway-Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Protein processing in endoplasmic reticulum+Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc gamma R-mediated phagocytosis-Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Inflammatory mediator regulation of TRP channels+Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway-Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Nicotinate and nicotinamide metabolism-Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc epsilon RI signaling pathway-Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome-Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Olfactory transduction-Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Thyroid hormone signaling pathway+Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+RNA degradation+Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-IL-17 signaling pathway-Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Arginine and proline metabolism-Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-GABAergic synapse-Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Ribosome biogenesis in eukaryotes+Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Cell cycle+Aldosterone synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway-Cortisol synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc gamma R-mediated phagocytosis-Cortisol synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-Cortisol synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Inflammatory mediator regulation of TRP channels+Cortisol synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway-Cortisol synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome-Cortisol synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Olfactory transduction-Cortisol synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-IL-17 signaling pathway-Cortisol synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Cell cycle+Cortisol synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc gamma R-mediated phagocytosis-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc epsilon RI signaling pathway-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-IL-17 signaling pathway-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Cell cycle+HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway+Phagosome+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Protein processing in endoplasmic reticulum-Phagosome+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids+Phagosome+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway+Phagosome+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Nicotinate and nicotinamide metabolism+Phagosome+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+RNA degradation-Phagosome+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Arginine and proline metabolism+Phagosome+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Ribosome biogenesis in eukaryotes-Phagosome+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Cell cycle-Phagosome+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Wnt signaling pathway+Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway-Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Protein processing in endoplasmic reticulum+Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc gamma R-mediated phagocytosis-Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Inflammatory mediator regulation of TRP channels+Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway-Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Nicotinate and nicotinamide metabolism-Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome-Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Olfactory transduction-Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+RNA degradation+Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-IL-17 signaling pathway-Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Cell cycle+Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Wnt signaling pathway+Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway-Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Protein processing in endoplasmic reticulum+Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc gamma R-mediated phagocytosis-Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Inflammatory mediator regulation of TRP channels+Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway-Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Nicotinate and nicotinamide metabolism-Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc epsilon RI signaling pathway-Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome-Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Olfactory transduction-Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Thyroid hormone signaling pathway+Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+RNA degradation+Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-IL-17 signaling pathway-Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Arginine and proline metabolism-Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-GABAergic synapse-Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Ribosome biogenesis in eukaryotes+Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Hippo signaling pathway+Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Cell cycle+Glucagon signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway-Thyroid hormone synthesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Protein processing in endoplasmic reticulum+Thyroid hormone synthesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc gamma R-mediated phagocytosis-Thyroid hormone synthesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-Thyroid hormone synthesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Inflammatory mediator regulation of TRP channels+Thyroid hormone synthesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway-Thyroid hormone synthesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Nicotinate and nicotinamide metabolism-Thyroid hormone synthesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc epsilon RI signaling pathway-Thyroid hormone synthesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome-Thyroid hormone synthesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Olfactory transduction-Thyroid hormone synthesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+RNA degradation+Thyroid hormone synthesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-IL-17 signaling pathway-Thyroid hormone synthesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Wnt signaling pathway+Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway-Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Protein processing in endoplasmic reticulum+Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc gamma R-mediated phagocytosis-Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Inflammatory mediator regulation of TRP channels+Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway-Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Nicotinate and nicotinamide metabolism-Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc epsilon RI signaling pathway-Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome-Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Olfactory transduction-Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+RNA degradation+Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-IL-17 signaling pathway-Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Arginine and proline metabolism-Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-GABAergic synapse-Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Ribosome biogenesis in eukaryotes+Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Hippo signaling pathway+Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Cell cycle+Melanogenesis-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc gamma R-mediated phagocytosis-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc gamma R-mediated phagocytosis-Regulation of lipolysis in adipocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-Regulation of lipolysis in adipocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Inflammatory mediator regulation of TRP channels+Regulation of lipolysis in adipocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway-Regulation of lipolysis in adipocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome-Regulation of lipolysis in adipocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Adipocytokine signaling pathway+GDCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Hippo signaling pathway-GDCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Wnt signaling pathway-Cell adhesion molecules+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway+Cell adhesion molecules+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Protein processing in endoplasmic reticulum-Cell adhesion molecules+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids+Cell adhesion molecules+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway+Cell adhesion molecules+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Nicotinate and nicotinamide metabolism+Cell adhesion molecules+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+RNA degradation-Cell adhesion molecules+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Ribosome biogenesis in eukaryotes-Cell adhesion molecules+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Cell cycle-Cell adhesion molecules+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	"Paraprevotella+Wnt signaling pathway+Parathyroid hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	"Paraprevotella-cGMP-PKG signaling pathway-Parathyroid hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	"Paraprevotella+Protein processing in endoplasmic reticulum+Parathyroid hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	"Paraprevotella-Fc gamma R-mediated phagocytosis-Parathyroid hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	"Paraprevotella-Biosynthesis of amino acids-Parathyroid hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	"Paraprevotella+Inflammatory mediator regulation of TRP channels+Parathyroid hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	"Paraprevotella-PPAR signaling pathway-Parathyroid hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	"Paraprevotella-Nicotinate and nicotinamide metabolism-Parathyroid hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	"Paraprevotella-Fc epsilon RI signaling pathway-Parathyroid hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	"Paraprevotella-Peroxisome-Parathyroid hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	"Paraprevotella-Olfactory transduction-Parathyroid hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	"Paraprevotella+RNA degradation+Parathyroid hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	"Paraprevotella-Arginine and proline metabolism-Parathyroid hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Wnt signaling pathway+Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway-Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Protein processing in endoplasmic reticulum+Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc gamma R-mediated phagocytosis-Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Inflammatory mediator regulation of TRP channels+Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway-Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Nicotinate and nicotinamide metabolism-Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc epsilon RI signaling pathway-Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome-Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Olfactory transduction-Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Thyroid hormone signaling pathway+Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+RNA degradation+Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-IL-17 signaling pathway-Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Arginine and proline metabolism-Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Hippo signaling pathway+Pancreatic secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Adipocytokine signaling pathway+Hypotaurine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	"Paraprevotella-Adipocytokine signaling pathway+Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	"Paraprevotella+Hippo signaling pathway-Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Arrhythmogenic right ventricular cardiomyopathy+18:0/18:1-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Thyroid hormone signaling pathway+18:0/18:1-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Hippo signaling pathway+18:0/18:1-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-Endocrine resistance-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-Calcium signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway-Calcium signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Nicotinate and nicotinamide metabolism-Calcium signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+RNA degradation+Calcium signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Arginine and proline metabolism-Calcium signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Wnt signaling pathway-Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway+Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc gamma R-mediated phagocytosis+Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids+Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Inflammatory mediator regulation of TRP channels-Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway+Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome+Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Epithelial cell signaling in Helicobacter pylori infection+Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Olfactory transduction+Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+RNA degradation-Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-IL-17 signaling pathway+Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Ribosome biogenesis in eukaryotes-Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Cell cycle-Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Wnt signaling pathway+Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway-Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Protein processing in endoplasmic reticulum+Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc gamma R-mediated phagocytosis-Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Inflammatory mediator regulation of TRP channels+Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway-Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Nicotinate and nicotinamide metabolism-Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc epsilon RI signaling pathway-Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome-Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Olfactory transduction-Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+RNA degradation+Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-IL-17 signaling pathway-Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Arginine and proline metabolism-Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Ribosome biogenesis in eukaryotes+Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Cell cycle+Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Wnt signaling pathway+Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-cGMP-PKG signaling pathway-Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Protein processing in endoplasmic reticulum+Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc gamma R-mediated phagocytosis-Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Biosynthesis of amino acids-Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Inflammatory mediator regulation of TRP channels+Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-PPAR signaling pathway-Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Nicotinate and nicotinamide metabolism-Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Fc epsilon RI signaling pathway-Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Peroxisome-Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Olfactory transduction-Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Thyroid hormone signaling pathway+Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+RNA degradation+Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-IL-17 signaling pathway-Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella-Arginine and proline metabolism-Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Hippo signaling pathway+Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
Paraprevotella	IL-1ra	Paraprevotella+Cell cycle+Endocrine and other factor-regulated calcium reabsorption-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-DS
TDCA+blood	IL-1ra	TDCA+blood-IL-1ra	Direct	serum_bileacids	serum_cytokines	0.155	0.0288	no	up	no	no	up	up	DM-DS
¦Ø-MCA+stool	IL-1ra	¦Ø-MCA+stool+CDCA+stool+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.919	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-16:0/18:2-PC+blood+20:3/16:0-PC+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-16:0/18:1-PC+blood+20:3/16:0-PC+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-18:1/16:0-PC+blood+20:3/16:0-PC+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-18:0/16:0-PC+blood+20:3/16:0-PC+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-16:0/20:3-PC+blood+18:0/18:0-PC+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-16:0/16:1-PC+blood+18:0/18:0-PC+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-16:0/16:1-PC+blood-18:2/20:4-PC+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-SFA+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-16:0/18:2-PC+blood-16:0/20:4-PI+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-16:0/18:2-PC+blood+16:0/20:4-PC+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-16:0/18:1-PC+blood+16:0/20:4-PC+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-16:0/16:1-PC+blood-16:0/20:4-PC+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-16:0/18:1-PC+blood-TDCA+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-18:0/16:0-PC+blood-TDCA+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-16:0/20:3-PC+blood+18:0/18:1-PC+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-16:0/16:1-PC+blood+18:0/18:1-PC+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-16:0/18:1-PC+blood+18:0/22:6-PA+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-GCDCA+blood+L-Alanine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-Cystine+blood+L-Alanine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-16:0/16:1-PC+blood+16:0/18:2-PI+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	"Gemmiger-12,13-EPOME+blood+16:0/18:2-PI+blood+IL-1ra"	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	Gemmiger+ErbB signaling pathway-L-Alanine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	Gemmiger+24:0+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	"Gemmiger-12,13-EPOME+blood-18:2/20:4-PC+blood-IL-1ra"	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	"Gemmiger+Signaling pathways regulating pluripotency of stem cells+Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	"Gemmiger+ErbB signaling pathway+Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	Gemmiger+Pathways in cancer-16:0/20:4-PI+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	Gemmiger+Signaling pathways regulating pluripotency of stem cells+12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	Gemmiger+Pathways in cancer+12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	Gemmiger+Colorectal cancer+12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	Gemmiger+Signaling pathways regulating pluripotency of stem cells+iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	Gemmiger+Pathways in cancer+iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	Gemmiger+ErbB signaling pathway+Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	Gemmiger+Signaling pathways regulating pluripotency of stem cells+LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	Gemmiger+Pathways in cancer+LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	Gemmiger+Pathways in cancer+Hypotaurine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
Gemmiger	IL-1ra	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Cortisol synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-DS
GDCA+stool	IL-1ra	GDCA+stool+UDCA+stool+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.656	0.0288	no	no	no	no	up	up	DM-DS
Methanobrevibacter	IL-1ra	Methanobrevibacter-Cystine+blood+L-Alanine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.629	0.0288	no	no	no	no	up	up	DM-DS
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool-18:2/20:4-PC+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	DM-DS
CDCA+stool	IL-1ra	CDCA+stool+IL-1ra	Direct	stool_bileacids	serum_cytokines	0.663	0.0288	no	no	no	no	up	up	DM-DS
CA+stool	IL-1ra	CA+stool-LCA+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.827	0.0288	no	no	no	no	up	up	DM-DS
CA+stool	IL-1ra	CA+stool+GCA+stool+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.827	0.0288	no	no	no	no	up	up	DM-DS
CA+stool	IL-1ra	CA+stool+CDCA+stool+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.827	0.0288	no	no	no	no	up	up	DM-DS
CA+stool	IL-1ra	CA+stool-iso-LCA+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.827	0.0288	no	no	no	no	up	up	DM-DS
CA+stool	IL-1ra	CA+stool+UDCA+stool+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.827	0.0288	no	no	no	no	up	up	DM-DS
HDCA+blood	IL-1ra	HDCA+blood+Hypotaurine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.483	0.0288	no	no	no	no	up	up	DM-DS
UDCA+stool	IL-1ra	UDCA+stool+IL-1ra	Direct	stool_bileacids	serum_cytokines	0.266	0.0288	no	no	no	no	up	up	DM-DS
TDCA+stool	IL-1ra	TDCA+stool-12-ketoDCA+blood+GDCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.963	0.0288	no	no	no	no	up	up	DM-DS
TDCA+stool	IL-1ra	TDCA+stool-HDCA+blood+Hypotaurine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.963	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human T-cell leukemia virus 1 infection-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human cytomegalovirus infection-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human immunodeficiency virus 1 infection-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Antigen processing and presentation-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Herpes simplex virus 1 infection-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Antigen processing and presentation-Regulation of lipolysis in adipocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human T-cell leukemia virus 1 infection-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human cytomegalovirus infection-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human immunodeficiency virus 1 infection-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Antigen processing and presentation-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Herpes simplex virus 1 infection-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Antigen processing and presentation+Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human T-cell leukemia virus 1 infection-12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human cytomegalovirus infection-12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human immunodeficiency virus 1 infection-12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Antigen processing and presentation-12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Herpes simplex virus 1 infection-12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human T-cell leukemia virus 1 infection+UDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Antigen processing and presentation+UDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Herpes simplex virus 1 infection+UDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Antigen processing and presentation-Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human T-cell leukemia virus 1 infection-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human cytomegalovirus infection-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human immunodeficiency virus 1 infection-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Antigen processing and presentation-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Herpes simplex virus 1 infection-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Antigen processing and presentation-Cortisol synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human T-cell leukemia virus 1 infection+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human cytomegalovirus infection+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human immunodeficiency virus 1 infection+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Antigen processing and presentation+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Herpes simplex virus 1 infection+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Antigen processing and presentation-Cocaine addiction-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	"Desulfovibrio+Antigen processing and presentation-Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Antigen processing and presentation-GnRH signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human cytomegalovirus infection-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Antigen processing and presentation-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
Desulfovibrio	IL-1ra	Desulfovibrio+Antigen processing and presentation-Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.27	0.0288	no	no	no	no	up	up	DM-DS
nutriCA+stool	IL-1ra	nutriCA+stool+18:0/22:6-PA+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.481	0.0288	no	no	no	no	up	up	DM-DS
nutriCA+stool	IL-1ra	nutriCA+stool+UDCA+stool+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.481	0.0288	no	no	no	no	up	up	DM-DS
nutriCA+stool	IL-1ra	nutriCA+stool+18:0/18:1-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.481	0.0288	no	no	no	no	up	up	DM-DS
nutriCA+stool	IL-1ra	nutriCA+stool+18:0/18:0-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.481	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human cytomegalovirus infection-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Antigen processing and presentation-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-iso-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Antigen processing and presentation-Regulation of lipolysis in adipocytes-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human cytomegalovirus infection-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Antigen processing and presentation-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-LCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Antigen processing and presentation+Salmonella infection+IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human cytomegalovirus infection-12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Antigen processing and presentation-12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-12-ketoDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+UDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Antigen processing and presentation+UDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+UDCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Antigen processing and presentation-Cushing syndrome-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human cytomegalovirus infection-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Antigen processing and presentation-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-Chemical carcinogenesis - receptor activation-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Antigen processing and presentation-Cortisol synthesis and secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human cytomegalovirus infection+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Antigen processing and presentation+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+GCA+stool+IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Antigen processing and presentation-Cocaine addiction-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	"Bilophila+Desulfovibrio+Antigen processing and presentation-Growth hormone synthesis, secretion and action-IL-1ra"	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Antigen processing and presentation-GnRH signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human cytomegalovirus infection-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Antigen processing and presentation-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
Bilophila	IL-1ra	Bilophila+Desulfovibrio+Antigen processing and presentation-Insulin secretion-IL-1ra	Indirect	Genus	serum_cytokines	0.528	0.0288	no	no	no	no	up	up	DM-DS
GDCA+blood	IL-1ra	GDCA+blood-IL-1ra	Direct	serum_bileacids	serum_cytokines	0.632	0.0288	no	no	no	no	up	up	DM-DS
P-hydroxyhippuric acid+urine	IL-1ra	P-hydroxyhippuric acid+urine-IL-1ra	Direct	urine_cometabolism	serum_cytokines	0.436	0.0288	no	no	no	no	up	up	DM-DS
acetic acid C2+blood	IL-1ra	acetic acid C2+blood+d18:1-22:1-SM+blood+HDCA+blood+Hypotaurine+blood-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.000193	0.0288	up	dn	no	no	up	up	DM-DS
acetic acid C2+blood	IL-1ra	acetic acid C2+blood+d18:1-20:1-SM+blood+HDCA+blood+Hypotaurine+blood-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.000193	0.0288	up	dn	no	no	up	up	DM-DS
isovaleric acid iso-C5+blood	IL-1ra	isovaleric acid iso-C5+blood+PUFA+blood+SFA+blood-P-hydroxyhippuric acid+urine-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.117	0.0288	no	no	no	no	up	up	DM-DS
Clostridium	IL-1ra	Clostridium+IL-1ra	Direct	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	DM-DS
T-¦Á-MCA+stool	IL-1ra	T-¦Á-MCA+stool-UDCA+stool+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.48	0.0288	no	no	no	no	up	up	DM-DS
12-ketoDCA+blood	IL-1ra	12-ketoDCA+blood+GDCA+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.517	0.0288	no	no	no	no	up	up	DM-DS
Butyricicoccus	IL-1ra	Butyricicoccus-18:2/20:4-PC+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.852	0.0288	no	no	no	no	up	up	DM-DS
Blautia	Eotaxin	Blautia+Dorea-Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	DM-DS
Parabacteroides	Eotaxin	Parabacteroides-16:0/18:2-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	4.19E-05	0.393	no	up	up	no	no	no	DM-DS
Dorea	Eotaxin	Dorea-Eotaxin	Direct	Genus	serum_cytokines	0.00362	0.393	up	no	dn	no	no	no	DM-DS
Faecalibacterium	Eotaxin	Faecalibacterium-Phenylacetic acid+stool-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Transcriptional misregulation in cancer-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+RNA transport+UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+Oocyte meiosis+UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Prolactin signaling pathway-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+Apelin signaling pathway+UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Phospholipase D signaling pathway-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Amoebiasis-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Chagas disease-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Acute myeloid leukemia-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+Glycolysis / Gluconeogenesis+UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+Long-term potentiation+UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Prolactin signaling pathway-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Relaxin signaling pathway-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+Oocyte meiosis+Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-cAMP signaling pathway-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Prolactin signaling pathway-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Amoebiasis-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Chagas disease-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Chronic myeloid leukemia-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Acute myeloid leukemia-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+Longevity regulating pathway - multiple species+Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+Long-term potentiation+Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Long-term depression-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Pathways in cancer-16:0/20:4-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+Parabacteroides-16:0/18:2-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Amoebiasis+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+16:1/16:1-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+16:0/22:6-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+20:3/18:0-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+18:0/20:4-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+Apelin signaling pathway-IL-17 signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Phospholipase D signaling pathway+IL-17 signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Pathways in cancer+L-Citrulline+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+16:0/20:5-PC+blood-L-Citrulline+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+Glycolysis / Gluconeogenesis-p53 signaling pathway+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Transcriptional misregulation in cancer-Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Pathways in cancer-Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Chronic myeloid leukemia-Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Choline metabolism in cancer-Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-MicroRNAs in cancer-Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	"Bacteroides-Growth hormone synthesis, secretion and action-Fluid shear stress and atherosclerosis-Eotaxin"	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+Glycolysis / Gluconeogenesis+Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-16:1/18:2-PG+blood+18:0/18:2-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+Long-term potentiation-18:0/18:2-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Long-term depression+18:0/18:2-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+Glycolysis / Gluconeogenesis+Leukocyte transendothelial migration-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+Glycolysis / Gluconeogenesis+Platelet activation-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+RNA transport-Neutrophil extracellular trap formation-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+Apelin signaling pathway-Neutrophil extracellular trap formation-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides-Phospholipase D signaling pathway+Neutrophil extracellular trap formation-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+RNA transport+Measles+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+Legionellosis+Measles+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Bacteroides	Eotaxin	Bacteroides+Leishmaniasis+Measles+Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-DS
Propionic acid+stool	Eotaxin	Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.0436	0.393	dn	no	up	no	no	no	DM-DS
[Ruminococcus]	Eotaxin	[Ruminococcus]-Progesterone-mediated oocyte maturation+Eotaxin	Indirect	Genus	serum_cytokines	0.0679	0.393	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	Eotaxin	[Ruminococcus]+16:0/18:2-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.0679	0.393	no	no	dn	no	no	no	DM-DS
GUDCA+blood	Eotaxin	GUDCA+blood+UDCA+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.0766	0.393	no	no	dn	no	no	no	DM-DS
UDCA+blood	Eotaxin	UDCA+blood+Eotaxin	Direct	serum_bileacids	serum_cytokines	0.0939	0.393	no	no	dn	no	no	no	DM-DS
Acetic acid+stool	Eotaxin	Acetic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.0656	0.393	dn	no	no	no	no	no	DM-DS
Alistipes	Eotaxin	Alistipes-Platelet activation-Eotaxin	Indirect	Genus	serum_cytokines	0.0114	0.393	no	up	no	no	no	no	DM-DS
Alistipes	Eotaxin	Alistipes-Oxytocin signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.0114	0.393	no	up	no	no	no	no	DM-DS
Alistipes	Eotaxin	Alistipes-Rap1 signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.0114	0.393	no	up	no	no	no	no	DM-DS
Butyricimonas	Eotaxin	Butyricimonas-L-Asparagine+blood+L-Citrulline+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.17	0.393	no	no	no	no	no	no	DM-DS
Butyricimonas	Eotaxin	Butyricimonas-iso-DCA+blood+L-Citrulline+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.17	0.393	no	no	no	no	no	no	DM-DS
Butyricimonas	Eotaxin	Butyricimonas-Butyric acid+stool+L-Citrulline+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.17	0.393	no	no	no	no	no	no	DM-DS
Butyricimonas	Eotaxin	Butyricimonas-Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin	Indirect	Genus	serum_cytokines	0.17	0.393	no	no	no	no	no	no	DM-DS
Collinsella	Eotaxin	Collinsella+Roseburia+16:0/18:2-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-DS
Collinsella	Eotaxin	Collinsella-Renin secretion+UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-DS
Collinsella	Eotaxin	Collinsella-Inflammatory mediator regulation of TRP channels+UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-DS
Collinsella	Eotaxin	Collinsella-Endocrine and other factor-regulated calcium reabsorption+P-hydroxyhippuric acid+urine+Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-DS
Collinsella	Eotaxin	Collinsella-GnRH signaling pathway-Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-DS
Collinsella	Eotaxin	Collinsella-Renin secretion-Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-DS
Collinsella	Eotaxin	Collinsella-Endocrine and other factor-regulated calcium reabsorption-Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-DS
Collinsella	Eotaxin	Collinsella-Inflammatory mediator regulation of TRP channels-Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-DS
Collinsella	Eotaxin	Collinsella-GnRH signaling pathway+HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-DS
Collinsella	Eotaxin	Collinsella-Endocrine and other factor-regulated calcium reabsorption+HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Osteoclast differentiation+Neutrophil extracellular trap formation-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Cellular senescence+Neutrophil extracellular trap formation-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Apoptosis+Neutrophil extracellular trap formation-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Osteoclast differentiation+IL-17 signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Cellular senescence+IL-17 signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Apoptosis+IL-17 signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+NF-kappa B signaling pathway+IL-17 signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Toll-like receptor signaling pathway+IL-17 signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+RIG-I-like receptor signaling pathway+IL-17 signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+C-type lectin receptor signaling pathway+IL-17 signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Dopaminergic synapse-Measles+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Hepatitis C+Measles+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Circadian entrainment-Measles+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Th17 cell differentiation+Measles+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Apoptosis+18:0/18:2-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Viral carcinogenesis-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Glucagon signaling pathway+HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Osteoclast differentiation-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Dopaminergic synapse+HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Cellular senescence-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Human papillomavirus infection-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Apoptosis-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Amphetamine addiction+HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-GnRH signaling pathway+HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Aldosterone synthesis and secretion+HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Fc epsilon RI signaling pathway-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Prolactin signaling pathway-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Glucagon signaling pathway+P-hydroxyhippuric acid+urine+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Aldosterone synthesis and secretion+P-hydroxyhippuric acid+urine+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Viral carcinogenesis-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Acute myeloid leukemia-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Cellular senescence-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Human papillomavirus infection-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Apoptosis-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Neurotrophin signaling pathway-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Chronic myeloid leukemia-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Toll-like receptor signaling pathway-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Fc epsilon RI signaling pathway-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Prostate cancer-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+C-type lectin receptor signaling pathway-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Prolactin signaling pathway-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+TNF signaling pathway-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+B cell receptor signaling pathway-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+NF-kappa B signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Insulin resistance-Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Circadian entrainment+Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Chronic myeloid leukemia-Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+RIG-I-like receptor signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Prostate cancer-Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+NF-kappa B signaling pathway-Oxytocin signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Circadian entrainment+Oxytocin signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+RIG-I-like receptor signaling pathway-Oxytocin signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+TNF signaling pathway-Oxytocin signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+NF-kappa B signaling pathway-Platelet activation-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Viral carcinogenesis+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Glucagon signaling pathway-Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Osteoclast differentiation+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Inflammatory mediator regulation of TRP channels-Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Cellular senescence+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Human papillomavirus infection+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Apoptosis+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Amphetamine addiction-Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Toll-like receptor signaling pathway+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-GnRH signaling pathway-Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Aldosterone synthesis and secretion-Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Fc epsilon RI signaling pathway+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+C-type lectin receptor signaling pathway+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+B cell receptor signaling pathway+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Glucagon signaling pathway+UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Osteoclast differentiation-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Inflammatory mediator regulation of TRP channels+UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Acute myeloid leukemia-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Apoptosis-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+NF-kappa B signaling pathway-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Amphetamine addiction+UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Toll-like receptor signaling pathway-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+RIG-I-like receptor signaling pathway-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina-Aldosterone synthesis and secretion+UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Fc epsilon RI signaling pathway-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+C-type lectin receptor signaling pathway-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+Prolactin signaling pathway-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Sarcina	Eotaxin	Sarcina+B cell receptor signaling pathway-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
Methanosphaera	Eotaxin	Methanosphaera-Roseburia+16:0/18:2-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.0703	0.393	no	no	no	no	no	no	DM-DS
iso-DCA+stool	Eotaxin	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.155	0.393	no	no	no	no	no	no	DM-DS
LCA+stool	Eotaxin	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	DM-DS
Akkermansia	Eotaxin	Akkermansia+P-hydroxyhippuric acid+urine+Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-DS
Bifidobacterium	Eotaxin	Bifidobacterium+Leukocyte transendothelial migration-Eotaxin	Indirect	Genus	serum_cytokines	0.105	0.393	no	dn	no	no	no	no	DM-DS
Ruminococcus	Eotaxin	"Ruminococcus-18:2n6c+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	DM-DS
Ruminococcus	Eotaxin	Ruminococcus-Alcoholism+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	DM-DS
Ruminococcus	Eotaxin	Ruminococcus-Alcoholism-Measles+Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	DM-DS
Ruminococcus	Eotaxin	Ruminococcus-Serotonergic synapse-Measles+Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	DM-DS
Ruminococcus	Eotaxin	Ruminococcus-20:4-LPC+blood+L-2-Aminobutyric acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	DM-DS
Ruminococcus	Eotaxin	Ruminococcus-EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	DM-DS
Ruminococcus	Eotaxin	Ruminococcus+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	DM-DS
Ruminococcus	Eotaxin	Ruminococcus-18:3n3+blood+L-2-Aminobutyric acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	DM-DS
Ruminococcus	Eotaxin	Ruminococcus+18:0/18:0-PC+blood+UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	DM-DS
GCDCA+blood	Eotaxin	GCDCA+blood+GUDCA+blood+UDCA+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.31	0.393	no	no	no	no	no	no	DM-DS
GCDCA+blood	Eotaxin	GCDCA+blood+HCA+blood+UDCA+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.31	0.393	no	no	no	no	no	no	DM-DS
ACA+blood	Eotaxin	ACA+blood+EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.338	0.393	no	no	no	no	no	no	DM-DS
DCA+stool	Eotaxin	DCA+stool+HDCA+stool+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.195	0.393	no	no	no	no	no	no	DM-DS
Butyric acid+stool	Eotaxin	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.102	0.393	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	Eotaxin	Butyric acid+stool+L-Citrulline+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.102	0.393	dn	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	Eotaxin	4-hydroxybenzoic acid+stool-DCA+stool+HDCA+stool+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.393	no	dn	no	no	no	no	DM-DS
Turicibacter	Eotaxin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Leukocyte transendothelial migration-Eotaxin	Indirect	Genus	serum_cytokines	0.269	0.393	no	no	no	no	no	no	DM-DS
Turicibacter	Eotaxin	Turicibacter+Desulfovibrio+Antigen processing and presentation-Progesterone-mediated oocyte maturation+Eotaxin	Indirect	Genus	serum_cytokines	0.269	0.393	no	no	no	no	no	no	DM-DS
Turicibacter	Eotaxin	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.269	0.393	no	no	no	no	no	no	DM-DS
Turicibacter	Eotaxin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.269	0.393	no	no	no	no	no	no	DM-DS
Turicibacter	Eotaxin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.269	0.393	no	no	no	no	no	no	DM-DS
Turicibacter	Eotaxin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.269	0.393	no	no	no	no	no	no	DM-DS
Turicibacter	Eotaxin	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.269	0.393	no	no	no	no	no	no	DM-DS
Turicibacter	Eotaxin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.269	0.393	no	no	no	no	no	no	DM-DS
Turicibacter	Eotaxin	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.269	0.393	no	no	no	no	no	no	DM-DS
Turicibacter	Eotaxin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.269	0.393	no	no	no	no	no	no	DM-DS
Turicibacter	Eotaxin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.269	0.393	no	no	no	no	no	no	DM-DS
Turicibacter	Eotaxin	Turicibacter+Desulfovibrio+Antigen processing and presentation-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.269	0.393	no	no	no	no	no	no	DM-DS
Turicibacter	Eotaxin	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.269	0.393	no	no	no	no	no	no	DM-DS
GCA+blood	Eotaxin	GCA+blood+HCA+blood+UDCA+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.16	0.393	no	no	no	no	no	no	DM-DS
ACA+stool	Eotaxin	ACA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.417	0.393	no	no	no	no	no	no	DM-DS
CDCA+blood	Eotaxin	CDCA+blood+UDCA+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.506	0.393	no	no	no	no	no	no	DM-DS
capric acid C6+blood	Eotaxin	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.433	0.393	no	no	no	no	no	no	DM-DS
Prevotella	Eotaxin	Prevotella-Measles+Eotaxin	Indirect	Genus	serum_cytokines	0.287	0.393	no	no	no	no	no	no	DM-DS
iso-DCA+blood	Eotaxin	iso-DCA+blood+L-Citrulline+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.38	0.393	no	no	no	no	no	no	DM-DS
HCA+stool	Eotaxin	HCA+stool-HDCA+stool+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.155	0.393	no	no	no	no	no	no	DM-DS
Roseburia	Eotaxin	Roseburia+16:0/18:2-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.495	0.393	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	Eotaxin	12-ketoDCA+stool+HDCA+stool+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.505	0.393	no	no	no	no	no	no	DM-DS
GLCA+blood	Eotaxin	GLCA+blood-SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.319	0.393	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	Eotaxin	L-Tryptophan+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.557	0.393	no	no	no	no	no	no	DM-DS
CA+blood	Eotaxin	CA+blood+UDCA+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.606	0.393	no	no	no	no	no	no	DM-DS
GUDCA+stool	Eotaxin	GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0085	0.393	no	dn	no	no	no	no	DM-DS
L-Phenylalanine+stool	Eotaxin	L-Phenylalanine+stool-UDCA+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.398	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool-GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool-HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool-Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool+GCDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool+GDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool+DPA+blood-nutriCA+blood+UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool+GCDCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool-Isovaleric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool-Isobutyric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool+GCDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool+UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool+GDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool-iso-LCA+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool+GCDCA+stool+16:0/16:1-PC+blood+16:0/18:2-PI+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool-12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool+GCDCA+stool+16:1/18:2-PG+blood+18:0/18:2-PI+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	GCA+stool+GCDCA+stool+16:0/18:2-PC+blood-16:0/20:4-PI+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
GCA+stool	Eotaxin	"GCA+stool+GDCA+stool+L-Lysine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-DS
Coprococcus	Eotaxin	Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	DM-DS
Coprococcus	Eotaxin	Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	DM-DS
Coprococcus	Eotaxin	Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	DM-DS
Oscillospira	Eotaxin	Oscillospira+Progesterone-mediated oocyte maturation+Eotaxin	Indirect	Genus	serum_cytokines	0.62	0.393	no	no	no	no	no	no	DM-DS
Oscillospira	Eotaxin	Oscillospira-Rap1 signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.62	0.393	no	no	no	no	no	no	DM-DS
Oscillospira	Eotaxin	Oscillospira+Spliceosome+Eotaxin	Indirect	Genus	serum_cytokines	0.62	0.393	no	no	no	no	no	no	DM-DS
Oscillospira	Eotaxin	Oscillospira-Platelet activation-Eotaxin	Indirect	Genus	serum_cytokines	0.62	0.393	no	no	no	no	no	no	DM-DS
HCA+blood	Eotaxin	HCA+blood+UDCA+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.544	0.393	no	no	no	no	no	no	DM-DS
iso-LCA+stool	Eotaxin	iso-LCA+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	DM-DS
DCA+blood	Eotaxin	DCA+blood+nutriCA+blood+UDCA+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.122	0.393	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	Eotaxin	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.33	0.393	no	no	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	Eotaxin	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Direct	urine_cometabolism	serum_cytokines	0.0125	0.393	up	up	no	no	no	no	DM-DS
nutriCA+blood	Eotaxin	nutriCA+blood+UDCA+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.726	0.393	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	DM-DS
TCA+stool	Eotaxin	TCA+stool+16:0/18:2-PI+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-DS
HDCA+stool	Eotaxin	HDCA+stool+Eotaxin	Direct	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	DM-DS
Lachnospira	Eotaxin	Lachnospira-p53 signaling pathway+Eotaxin	Indirect	Genus	serum_cytokines	0.279	0.393	no	no	no	no	no	no	DM-DS
Lachnospira	Eotaxin	Lachnospira+Platelet activation-Eotaxin	Indirect	Genus	serum_cytokines	0.279	0.393	no	no	no	no	no	no	DM-DS
Lachnospira	Eotaxin	Lachnospira-Progesterone-mediated oocyte maturation+Eotaxin	Indirect	Genus	serum_cytokines	0.279	0.393	no	no	no	no	no	no	DM-DS
Lachnospira	Eotaxin	Lachnospira+Rap1 signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.279	0.393	no	no	no	no	no	no	DM-DS
Lachnospira	Eotaxin	Lachnospira-Spliceosome+Eotaxin	Indirect	Genus	serum_cytokines	0.279	0.393	no	no	no	no	no	no	DM-DS
Lachnospira	Eotaxin	Lachnospira+Leukocyte transendothelial migration-Eotaxin	Indirect	Genus	serum_cytokines	0.279	0.393	no	no	no	no	no	no	DM-DS
Lachnospira	Eotaxin	Lachnospira+Oxytocin signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.279	0.393	no	no	no	no	no	no	DM-DS
Lachnospira	Eotaxin	Lachnospira+Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.279	0.393	no	no	no	no	no	no	DM-DS
Fusobacterium	Eotaxin	Fusobacterium-Intestinal immune network for IgA production-L-Citrulline+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.628	0.393	no	no	no	no	no	no	DM-DS
Fusobacterium	Eotaxin	Fusobacterium-Intestinal immune network for IgA production-Progesterone-mediated oocyte maturation+Eotaxin	Indirect	Genus	serum_cytokines	0.628	0.393	no	no	no	no	no	no	DM-DS
Fusobacterium	Eotaxin	Fusobacterium-Intestinal immune network for IgA production-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.628	0.393	no	no	no	no	no	no	DM-DS
Fusobacterium	Eotaxin	Fusobacterium-18:0/18:0-PC+blood+UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.628	0.393	no	no	no	no	no	no	DM-DS
Fusobacterium	Eotaxin	Fusobacterium-16:0/20:3-PC+blood+UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.628	0.393	no	no	no	no	no	no	DM-DS
Fusobacterium	Eotaxin	Fusobacterium-18:0/18:1-PC+blood+UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.628	0.393	no	no	no	no	no	no	DM-DS
Fusobacterium	Eotaxin	Fusobacterium-GUDCA+blood+UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.628	0.393	no	no	no	no	no	no	DM-DS
Fusobacterium	Eotaxin	Fusobacterium-16:0/18:2-PC+blood-16:0/20:4-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.628	0.393	no	no	no	no	no	no	DM-DS
GCDCA+stool	Eotaxin	GCDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0471	0.393	no	dn	no	no	no	no	DM-DS
GCDCA+stool	Eotaxin	GCDCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0471	0.393	no	dn	no	no	no	no	DM-DS
GCDCA+stool	Eotaxin	GCDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0471	0.393	no	dn	no	no	no	no	DM-DS
GCDCA+stool	Eotaxin	GCDCA+stool+16:0/18:2-PC+blood-16:0/20:4-PI+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0471	0.393	no	dn	no	no	no	no	DM-DS
GCDCA+stool	Eotaxin	GCDCA+stool+16:0/16:1-PC+blood+16:0/18:2-PI+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0471	0.393	no	dn	no	no	no	no	DM-DS
GCDCA+stool	Eotaxin	GCDCA+stool+16:1/18:2-PG+blood+18:0/18:2-PI+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0471	0.393	no	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool+Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool+Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:1-PC+blood+UDCA+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool-nutriCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:0-PC+blood+UDCA+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool-nutriCA+stool-13-HODE+blood-16:0/20:4-PI+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/22:6-PA+blood-P-hydroxyhippuric acid+urine+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool-nutriCA+stool-AA+blood+L-2-Aminobutyric acid+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-DS
Odoribacter	Eotaxin	Odoribacter-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.798	0.393	no	no	no	no	no	no	DM-DS
Odoribacter	Eotaxin	Odoribacter+Neuroactive ligand-receptor interaction-Eotaxin	Indirect	Genus	serum_cytokines	0.798	0.393	no	no	no	no	no	no	DM-DS
Odoribacter	Eotaxin	Odoribacter+16:0/20:4-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.798	0.393	no	no	no	no	no	no	DM-DS
Actinomyces	Eotaxin	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.621	0.393	no	no	no	no	no	no	DM-DS
Actinomyces	Eotaxin	Actinomyces+Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin	Indirect	Genus	serum_cytokines	0.621	0.393	no	no	no	no	no	no	DM-DS
Actinomyces	Eotaxin	Actinomyces+Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin	Indirect	Genus	serum_cytokines	0.621	0.393	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	Eotaxin	"2-hydroxyphenylacetic acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	urine_cometabolism	serum_cytokines	0.763	0.393	no	no	no	no	no	no	DM-DS
Kynurenic acid+stool	Eotaxin	Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.037	0.393	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	Eotaxin	Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.037	0.393	dn	dn	no	no	no	no	DM-DS
Caproic acid+stool	Eotaxin	Caproic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.882	0.393	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Eotaxin	Caproic acid+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.882	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella+AMPK signaling pathway-Neutrophil extracellular trap formation-Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella+Phosphatidylinositol signaling system-Neutrophil extracellular trap formation-Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella+AMPK signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella-Yersinia infection+Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella-Influenza A+Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella-Yersinia infection-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella+Phosphatidylinositol signaling system+Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella-Influenza A-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella-Yersinia infection-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella-Influenza A-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella-Yersinia infection-UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella+Phosphatidylinositol signaling system+Progesterone-mediated oocyte maturation+Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella+AMPK signaling pathway-IL-17 signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella+Phosphatidylinositol signaling system-IL-17 signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella+AMPK signaling pathway+L-Citrulline+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella+Phosphatidylinositol signaling system-Lysosome-Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella+Phosphatidylinositol signaling system+p53 signaling pathway+Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella+AMPK signaling pathway-Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella-Yersinia infection+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella+Phosphatidylinositol signaling system-Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella-Influenza A+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella-Yersinia infection+18:0/18:2-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Eggerthella	Eotaxin	Eggerthella+Phosphatidylinositol signaling system-18:0/18:2-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	DM-DS
Anaerotruncus	Eotaxin	"Anaerotruncus-Ruminococcus-18:2n6c+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	Genus	serum_cytokines	0.904	0.393	no	no	no	no	no	no	DM-DS
Anaerotruncus	Eotaxin	Anaerotruncus-Ruminococcus-Alcoholism+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.904	0.393	no	no	no	no	no	no	DM-DS
Anaerotruncus	Eotaxin	Anaerotruncus-Ruminococcus-Alcoholism-Measles+Eotaxin	Indirect	Genus	serum_cytokines	0.904	0.393	no	no	no	no	no	no	DM-DS
Anaerotruncus	Eotaxin	Anaerotruncus-Ruminococcus-Serotonergic synapse-Measles+Eotaxin	Indirect	Genus	serum_cytokines	0.904	0.393	no	no	no	no	no	no	DM-DS
Anaerotruncus	Eotaxin	Anaerotruncus-Ruminococcus-20:4-LPC+blood+L-2-Aminobutyric acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.904	0.393	no	no	no	no	no	no	DM-DS
Anaerotruncus	Eotaxin	Anaerotruncus-Ruminococcus-EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.904	0.393	no	no	no	no	no	no	DM-DS
Anaerotruncus	Eotaxin	Anaerotruncus-Ruminococcus+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.904	0.393	no	no	no	no	no	no	DM-DS
Anaerotruncus	Eotaxin	Anaerotruncus-Ruminococcus-18:3n3+blood+L-2-Aminobutyric acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.904	0.393	no	no	no	no	no	no	DM-DS
Anaerotruncus	Eotaxin	Anaerotruncus-Ruminococcus+18:0/18:0-PC+blood+UDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.904	0.393	no	no	no	no	no	no	DM-DS
Anaerostipes	Eotaxin	Anaerostipes+Eotaxin	Direct	Genus	serum_cytokines	0.568	0.393	no	no	no	no	no	no	DM-DS
TUDCA+stool	Eotaxin	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.241	0.393	no	no	no	no	no	no	DM-DS
TUDCA+stool	Eotaxin	TUDCA+stool+9-HODE+blood+AA+blood+L-2-Aminobutyric acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.241	0.393	no	no	no	no	no	no	DM-DS
TUDCA+stool	Eotaxin	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-L-2-Aminobutyric acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.241	0.393	no	no	no	no	no	no	DM-DS
TUDCA+stool	Eotaxin	TUDCA+stool-14:0/18:2-PC+blood+24:0+blood-P-hydroxyhippuric acid+urine+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.241	0.393	no	no	no	no	no	no	DM-DS
TUDCA+stool	Eotaxin	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+L-Citrulline+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.241	0.393	no	no	no	no	no	no	DM-DS
TUDCA+stool	Eotaxin	TUDCA+stool-d18:1-14:0-SM+blood-L-Asparagine+blood+L-Citrulline+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.241	0.393	no	no	no	no	no	no	DM-DS
TUDCA+stool	Eotaxin	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood-UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.241	0.393	no	no	no	no	no	no	DM-DS
TUDCA+stool	Eotaxin	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.241	0.393	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	DM-DS
Paraprevotella	Eotaxin	Paraprevotella-IL-17 signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	Eotaxin	¦Ø-MCA+stool-L-Tyrosine+stool-UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.919	0.393	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	Eotaxin	¦Ø-MCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.919	0.393	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	Eotaxin	Phenylacetic acid+stool-UDCA+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.785	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+PI3K-Akt signaling pathway+Measles+Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	"Gemmiger-12,13-EPOME+blood+16:0/18:2-PI+blood-Eotaxin"	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Platelet activation-Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+ErbB signaling pathway-Platelet activation-Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+ErbB signaling pathway+p53 signaling pathway+Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Progesterone-mediated oocyte maturation+Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+ErbB signaling pathway+Progesterone-mediated oocyte maturation+Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+Pathways in cancer-Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+ErbB signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+Gastric cancer-Fluid shear stress and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+Gastric cancer-Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+24:0+blood-P-hydroxyhippuric acid+urine+Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+Pathways in cancer-16:0/20:4-PI+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+Pathways in cancer+L-Citrulline+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Leukocyte transendothelial migration-Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Neutrophil extracellular trap formation-Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Oxytocin signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
Gemmiger	Eotaxin	Gemmiger+ErbB signaling pathway-Oxytocin signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-DS
GDCA+stool	Eotaxin	GDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-DS
GDCA+stool	Eotaxin	GDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-DS
GDCA+stool	Eotaxin	"GDCA+stool+L-Lysine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-DS
Methanobrevibacter	Eotaxin	Methanobrevibacter-Alcoholism-Measles+Eotaxin	Indirect	Genus	serum_cytokines	0.629	0.393	no	no	no	no	no	no	DM-DS
Methanobrevibacter	Eotaxin	Methanobrevibacter-Alcoholism+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.629	0.393	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	Eotaxin	L-Tyrosine+stool-UDCA+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.44	0.393	no	no	no	no	no	no	DM-DS
CDCA+stool	Eotaxin	CDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	DM-DS
CDCA+stool	Eotaxin	CDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	DM-DS
CA+stool	Eotaxin	CA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	DM-DS
HDCA+blood	Eotaxin	HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.483	0.393	no	no	no	no	no	no	DM-DS
UDCA+stool	Eotaxin	UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.266	0.393	no	no	no	no	no	no	DM-DS
TDCA+stool	Eotaxin	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.963	0.393	no	no	no	no	no	no	DM-DS
TDCA+stool	Eotaxin	TDCA+stool-12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.963	0.393	no	no	no	no	no	no	DM-DS
TDCA+stool	Eotaxin	TDCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.963	0.393	no	no	no	no	no	no	DM-DS
TDCA+stool	Eotaxin	TDCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.963	0.393	no	no	no	no	no	no	DM-DS
TDCA+stool	Eotaxin	TDCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.963	0.393	no	no	no	no	no	no	DM-DS
TDCA+stool	Eotaxin	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.963	0.393	no	no	no	no	no	no	DM-DS
TDCA+stool	Eotaxin	TDCA+stool-HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.963	0.393	no	no	no	no	no	no	DM-DS
TDCA+stool	Eotaxin	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.963	0.393	no	no	no	no	no	no	DM-DS
Desulfovibrio	Eotaxin	Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.27	0.393	no	no	no	no	no	no	DM-DS
Desulfovibrio	Eotaxin	Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.27	0.393	no	no	no	no	no	no	DM-DS
Desulfovibrio	Eotaxin	Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.27	0.393	no	no	no	no	no	no	DM-DS
Desulfovibrio	Eotaxin	Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.27	0.393	no	no	no	no	no	no	DM-DS
Desulfovibrio	Eotaxin	Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.27	0.393	no	no	no	no	no	no	DM-DS
Desulfovibrio	Eotaxin	Desulfovibrio+Antigen processing and presentation-Progesterone-mediated oocyte maturation+Eotaxin	Indirect	Genus	serum_cytokines	0.27	0.393	no	no	no	no	no	no	DM-DS
Desulfovibrio	Eotaxin	Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.27	0.393	no	no	no	no	no	no	DM-DS
Desulfovibrio	Eotaxin	Desulfovibrio+Antigen processing and presentation+Leukocyte transendothelial migration-Eotaxin	Indirect	Genus	serum_cytokines	0.27	0.393	no	no	no	no	no	no	DM-DS
Desulfovibrio	Eotaxin	Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.27	0.393	no	no	no	no	no	no	DM-DS
Desulfovibrio	Eotaxin	Desulfovibrio+Human cytomegalovirus infection-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.27	0.393	no	no	no	no	no	no	DM-DS
Desulfovibrio	Eotaxin	Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.27	0.393	no	no	no	no	no	no	DM-DS
Desulfovibrio	Eotaxin	Desulfovibrio+Antigen processing and presentation-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.27	0.393	no	no	no	no	no	no	DM-DS
Desulfovibrio	Eotaxin	Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.27	0.393	no	no	no	no	no	no	DM-DS
nutriCA+stool	Eotaxin	nutriCA+stool+18:0/22:6-PA+blood-P-hydroxyhippuric acid+urine+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.481	0.393	no	no	no	no	no	no	DM-DS
nutriCA+stool	Eotaxin	nutriCA+stool+18:0/18:1-PC+blood+UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.481	0.393	no	no	no	no	no	no	DM-DS
nutriCA+stool	Eotaxin	nutriCA+stool+18:0/18:0-PC+blood+UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.481	0.393	no	no	no	no	no	no	DM-DS
nutriCA+stool	Eotaxin	nutriCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.481	0.393	no	no	no	no	no	no	DM-DS
nutriCA+stool	Eotaxin	nutriCA+stool-13-HODE+blood-16:0/20:4-PI+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.481	0.393	no	no	no	no	no	no	DM-DS
nutriCA+stool	Eotaxin	nutriCA+stool-AA+blood+L-2-Aminobutyric acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.481	0.393	no	no	no	no	no	no	DM-DS
nutriCA+stool	Eotaxin	nutriCA+stool+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.481	0.393	no	no	no	no	no	no	DM-DS
Bilophila	Eotaxin	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.528	0.393	no	no	no	no	no	no	DM-DS
Bilophila	Eotaxin	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.528	0.393	no	no	no	no	no	no	DM-DS
Bilophila	Eotaxin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.528	0.393	no	no	no	no	no	no	DM-DS
Bilophila	Eotaxin	Bilophila+Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.528	0.393	no	no	no	no	no	no	DM-DS
Bilophila	Eotaxin	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.528	0.393	no	no	no	no	no	no	DM-DS
Bilophila	Eotaxin	Bilophila+Desulfovibrio+Antigen processing and presentation-Progesterone-mediated oocyte maturation+Eotaxin	Indirect	Genus	serum_cytokines	0.528	0.393	no	no	no	no	no	no	DM-DS
Bilophila	Eotaxin	Bilophila+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency+Eotaxin	Indirect	Genus	serum_cytokines	0.528	0.393	no	no	no	no	no	no	DM-DS
Bilophila	Eotaxin	Bilophila+Desulfovibrio+Antigen processing and presentation+Leukocyte transendothelial migration-Eotaxin	Indirect	Genus	serum_cytokines	0.528	0.393	no	no	no	no	no	no	DM-DS
Bilophila	Eotaxin	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.528	0.393	no	no	no	no	no	no	DM-DS
Bilophila	Eotaxin	Bilophila+Desulfovibrio+Human cytomegalovirus infection-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.528	0.393	no	no	no	no	no	no	DM-DS
Bilophila	Eotaxin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.528	0.393	no	no	no	no	no	no	DM-DS
Bilophila	Eotaxin	Bilophila+Desulfovibrio+Antigen processing and presentation-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.528	0.393	no	no	no	no	no	no	DM-DS
Bilophila	Eotaxin	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool+Eotaxin	Indirect	Genus	serum_cytokines	0.528	0.393	no	no	no	no	no	no	DM-DS
GDCA+blood	Eotaxin	GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.632	0.393	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	Eotaxin	P-hydroxyhippuric acid+urine+Eotaxin	Direct	urine_cometabolism	serum_cytokines	0.436	0.393	no	no	no	no	no	no	DM-DS
acetic acid C2+blood	Eotaxin	acetic acid C2+blood+d18:1-20:1-SM+blood-GUDCA+blood+UDCA+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.000193	0.393	up	dn	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	Eotaxin	isovaleric acid iso-C5+blood+PUFA+blood+SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.117	0.393	no	no	no	no	no	no	DM-DS
Clostridium	Eotaxin	Clostridium-Eotaxin	Direct	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	Eotaxin	12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.517	0.393	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	Eotaxin	12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.517	0.393	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	Eotaxin	12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.517	0.393	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	Eotaxin	12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.517	0.393	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	Eotaxin	12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.517	0.393	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	Eotaxin	12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.517	0.393	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	Eotaxin	12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.517	0.393	no	no	no	no	no	no	DM-DS
Butyricicoccus	Eotaxin	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood-Eotaxin"	Indirect	Genus	serum_cytokines	0.852	0.393	no	no	no	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia+Longevity regulating pathway - multiple species-Relaxin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia+Longevity regulating pathway - multiple species+Primary immunodeficiency-PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia+Dorea+Glycolysis / Gluconeogenesis-PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia+Peroxisome+Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia+Longevity regulating pathway - multiple species-Adipocytokine signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia+Longevity regulating pathway - multiple species+Hematopoietic cell lineage-PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	"Blautia+Longevity regulating pathway - multiple species-Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia-Indole-3-Acetic acid+stool-nutriCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia+CA+stool+nutriCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia+CDCA+stool+nutriCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia+Cystine+blood-d18:1-14:0-SM+blood-PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia+Peroxisome+C-type lectin receptor signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia+Peroxisome+Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia-Dopaminergic synapse-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia-Thyroid hormone synthesis-DPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia-Dopaminergic synapse-DPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia+GCA+stool+DPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia+Peroxisome+Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia-Dopaminergic synapse-Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia+Peroxisome+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia-Dopaminergic synapse-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia-Dopaminergic synapse-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia-Dopaminergic synapse-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia+Longevity regulating pathway - multiple species-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia-Calcium signaling pathway-16:1/16:1-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia-Calcium signaling pathway-18:0/22:6-PA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia-14:0/18:2-PC+blood-L-Ornithine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia-16:0/18:3-PC+blood-L-Ornithine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia-Calcium signaling pathway+Long-term depression+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Blautia	PDGF-bb	Blautia+Longevity regulating pathway - multiple species-Long-term depression+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-DS
Parabacteroides	PDGF-bb	Parabacteroides+d18:1-14:0-SM+blood-PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	DM-DS
Dorea	PDGF-bb	Dorea+Glycolysis / Gluconeogenesis-PDGF-bb	Indirect	Genus	serum_cytokines	0.00362	0.111	up	no	dn	no	no	no	DM-DS
Faecalibacterium	PDGF-bb	Faecalibacterium+PDGF-bb	Direct	Genus	serum_cytokines	0.0039	0.111	no	dn	dn	no	no	no	DM-DS
Bacteroides	PDGF-bb	Bacteroides-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.000267	0.111	dn	dn	up	no	no	no	DM-DS
Bacteroides	PDGF-bb	Bacteroides-Relaxin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.000267	0.111	dn	dn	up	no	no	no	DM-DS
Bacteroides	PDGF-bb	Bacteroides-cAMP signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.000267	0.111	dn	dn	up	no	no	no	DM-DS
Bacteroides	PDGF-bb	Bacteroides-Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.000267	0.111	dn	dn	up	no	no	no	DM-DS
Bacteroides	PDGF-bb	Bacteroides+16:1/16:1-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.000267	0.111	dn	dn	up	no	no	no	DM-DS
Bacteroides	PDGF-bb	Bacteroides-Phospholipase D signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.000267	0.111	dn	dn	up	no	no	no	DM-DS
Bacteroides	PDGF-bb	Bacteroides-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.000267	0.111	dn	dn	up	no	no	no	DM-DS
Bacteroides	PDGF-bb	Bacteroides-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.000267	0.111	dn	dn	up	no	no	no	DM-DS
Bacteroides	PDGF-bb	Bacteroides-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.000267	0.111	dn	dn	up	no	no	no	DM-DS
Bacteroides	PDGF-bb	Bacteroides+20:3/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.000267	0.111	dn	dn	up	no	no	no	DM-DS
Bacteroides	PDGF-bb	"Bacteroides-Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.000267	0.111	dn	dn	up	no	no	no	DM-DS
Bacteroides	PDGF-bb	Bacteroides+Glycolysis / Gluconeogenesis-PDGF-bb	Indirect	Genus	serum_cytokines	0.000267	0.111	dn	dn	up	no	no	no	DM-DS
Bacteroides	PDGF-bb	Bacteroides-Long-term depression+PDGF-bb	Indirect	Genus	serum_cytokines	0.000267	0.111	dn	dn	up	no	no	no	DM-DS
Propionic acid+stool	PDGF-bb	Propionic acid+stool+18:0-LPE+blood-DPA+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0436	0.111	dn	no	up	no	no	no	DM-DS
Propionic acid+stool	PDGF-bb	Propionic acid+stool-16:0/16:0-PC+blood+18:0/22:6-PA+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0436	0.111	dn	no	up	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Tight junction-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-ErbB signaling pathway+Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-JAK-STAT signaling pathway+Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-MicroRNAs in cancer+Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-Pathways in cancer+Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	"[Ruminococcus]+Tight junction-Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	"[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	"[Ruminococcus]-FoxO signaling pathway+Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	"[Ruminococcus]-ErbB signaling pathway+Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	"[Ruminococcus]-JAK-STAT signaling pathway+Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	"[Ruminococcus]-Platinum drug resistance+Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-ErbB signaling pathway+Relaxin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-JAK-STAT signaling pathway+Relaxin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-JAK-STAT signaling pathway+DPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-JAK-STAT signaling pathway+Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Huntington disease-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Non-alcoholic fatty liver disease-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Alzheimer disease-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Parkinson disease-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+18:0/18:1-PE+blood-Ethanolamine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells-16:1/16:1-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-Gastric cancer-16:1/16:1-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Tight junction+Hematopoietic cell lineage-PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-JAK-STAT signaling pathway-Hematopoietic cell lineage-PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Tight junction-Neurotrophin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-ErbB signaling pathway+Neurotrophin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-JAK-STAT signaling pathway+Neurotrophin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Tight junction-Adipocytokine signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-JAK-STAT signaling pathway+Adipocytokine signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-18:0/20:4-PC+blood+20:3/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+18:0/18:1-PE+blood-20:3/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-18:1/20:4-PC+blood+20:3/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-Glioma-20:3/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Tight junction-Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-FoxO signaling pathway+Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-ErbB signaling pathway+Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-JAK-STAT signaling pathway+Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Tight junction-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-ErbB signaling pathway+Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-JAK-STAT signaling pathway+Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-MicroRNAs in cancer+Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-Pathways in cancer+Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-FoxO signaling pathway+Phospholipase D signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-ErbB signaling pathway+Phospholipase D signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Tight junction-C-type lectin receptor signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-FoxO signaling pathway+C-type lectin receptor signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-ErbB signaling pathway+C-type lectin receptor signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Tight junction-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-FoxO signaling pathway+Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-ErbB signaling pathway+Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-JAK-STAT signaling pathway+Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Huntington disease-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Alzheimer disease-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Tight junction-TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-FoxO signaling pathway+TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-ErbB signaling pathway+TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-JAK-STAT signaling pathway+TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-Progesterone-mediated oocyte maturation+Primary immunodeficiency-PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-Platinum drug resistance+Primary immunodeficiency-PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Tight junction-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Shigellosis-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-FoxO signaling pathway+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-ErbB signaling pathway+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-JAK-STAT signaling pathway+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Huntington disease-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-Platinum drug resistance+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Non-alcoholic fatty liver disease-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-Pathways in cancer+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Alzheimer disease-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Parkinson disease-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-MicroRNAs in cancer+L-Ornithine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-DS
GUDCA+blood	PDGF-bb	GUDCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.0766	0.111	no	no	dn	no	no	no	DM-DS
UDCA+blood	PDGF-bb	UDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.0939	0.111	no	no	dn	no	no	no	DM-DS
Acetic acid+stool	PDGF-bb	Acetic acid+stool-18:0/18:0-PS+blood+d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0656	0.111	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	PDGF-bb	Acetic acid+stool-16:0/18:0-PS+blood-Ethanolamine+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0656	0.111	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	PDGF-bb	Acetic acid+stool-18:0/18:0-PS+blood-Ethanolamine+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0656	0.111	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	PDGF-bb	Acetic acid+stool-18:0/18:0-PS+blood+18:0/18:1-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0656	0.111	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	PDGF-bb	Acetic acid+stool-18:0/18:0-PS+blood-L-Ornithine+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0656	0.111	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	PDGF-bb	Acetic acid+stool-16:0/18:0-PS+blood+18:0/22:6-PA+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0656	0.111	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	PDGF-bb	Acetic acid+stool-18:0/18:0-PS+blood+18:0/22:6-PA+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0656	0.111	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	PDGF-bb	Acetic acid+stool-14:0+blood-20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0656	0.111	dn	no	no	no	no	no	DM-DS
Alistipes	PDGF-bb	Alistipes+nutriCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.0114	0.111	no	up	no	no	no	no	DM-DS
Butyricimonas	PDGF-bb	Butyricimonas-20:4-LPA+blood+Ethanolamine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.17	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	Collinsella-Renin secretion-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	Collinsella-Inflammatory mediator regulation of TRP channels-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	Collinsella-Renin secretion-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	Collinsella-Endocrine and other factor-regulated calcium reabsorption-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	Collinsella-Inflammatory mediator regulation of TRP channels-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	Collinsella-Inflammatory mediator regulation of TRP channels-Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	Collinsella-Renin secretion-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	Collinsella-Inflammatory mediator regulation of TRP channels-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	Collinsella-Renin secretion-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	Collinsella-Inflammatory mediator regulation of TRP channels-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	Collinsella-Renin secretion-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	Collinsella-Inflammatory mediator regulation of TRP channels-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	Collinsella-Renin secretion-DPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	Collinsella-GnRH signaling pathway-18:0/22:6-PA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	Collinsella-Renin secretion-Ethanolamine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	Collinsella-Inflammatory mediator regulation of TRP channels-Ethanolamine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	"Collinsella-GnRH signaling pathway+Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Collinsella	PDGF-bb	Collinsella+Roseburia+Faecalibacterium+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-DS
Sarcina	PDGF-bb	Sarcina+Neurotrophin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0703	0.111	no	no	no	no	no	no	DM-DS
Sarcina	PDGF-bb	Sarcina+Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.0703	0.111	no	no	no	no	no	no	DM-DS
Sarcina	PDGF-bb	Sarcina+Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.0703	0.111	no	no	no	no	no	no	DM-DS
Sarcina	PDGF-bb	Sarcina+C-type lectin receptor signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0703	0.111	no	no	no	no	no	no	DM-DS
Sarcina	PDGF-bb	Sarcina+Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0703	0.111	no	no	no	no	no	no	DM-DS
Sarcina	PDGF-bb	Sarcina+TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0703	0.111	no	no	no	no	no	no	DM-DS
Methanosphaera	PDGF-bb	Methanosphaera-Roseburia+Faecalibacterium+PDGF-bb	Indirect	Genus	serum_cytokines	0.0703	0.111	no	no	no	no	no	no	DM-DS
iso-DCA+stool	PDGF-bb	iso-DCA+stool+Propionic acid+stool+18:0-LPE+blood-DPA+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.155	0.111	no	no	no	no	no	no	DM-DS
iso-DCA+stool	PDGF-bb	iso-DCA+stool+Propionic acid+stool-16:0/16:0-PC+blood+18:0/22:6-PA+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.155	0.111	no	no	no	no	no	no	DM-DS
LCA+stool	PDGF-bb	LCA+stool-TDCA+stool-12-ketoDCA+blood+Ethanolamine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.314	0.111	no	no	no	no	no	no	DM-DS
LCA+stool	PDGF-bb	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:0/18:1-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.314	0.111	no	no	no	no	no	no	DM-DS
LCA+stool	PDGF-bb	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:0/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.314	0.111	no	no	no	no	no	no	DM-DS
Akkermansia	PDGF-bb	Akkermansia+Proteoglycans in cancer+d18:1-14:0-SM+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.23	0.111	no	no	no	no	no	no	DM-DS
Akkermansia	PDGF-bb	Akkermansia+Proteoglycans in cancer-Ethanolamine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.23	0.111	no	no	no	no	no	no	DM-DS
Akkermansia	PDGF-bb	Akkermansia-Longevity regulating pathway+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.23	0.111	no	no	no	no	no	no	DM-DS
Akkermansia	PDGF-bb	Akkermansia-Longevity regulating pathway+Adipocytokine signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.23	0.111	no	no	no	no	no	no	DM-DS
Akkermansia	PDGF-bb	Akkermansia-Cytokine-cytokine receptor interaction+16:1/16:1-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.23	0.111	no	no	no	no	no	no	DM-DS
Akkermansia	PDGF-bb	Akkermansia-Cytokine-cytokine receptor interaction-Cytosolic DNA-sensing pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.23	0.111	no	no	no	no	no	no	DM-DS
Akkermansia	PDGF-bb	Akkermansia-Longevity regulating pathway-Hematopoietic cell lineage-PDGF-bb	Indirect	Genus	serum_cytokines	0.23	0.111	no	no	no	no	no	no	DM-DS
Akkermansia	PDGF-bb	"Akkermansia-Longevity regulating pathway+Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.23	0.111	no	no	no	no	no	no	DM-DS
Bifidobacterium	PDGF-bb	Bifidobacterium-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	DM-DS
Bifidobacterium	PDGF-bb	Bifidobacterium+Glycolysis / Gluconeogenesis-PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	DM-DS
Ruminococcus	PDGF-bb	Ruminococcus-PDGF-bb	Direct	Genus	serum_cytokines	0.335	0.111	no	no	no	no	no	no	DM-DS
GCDCA+blood	PDGF-bb	GCDCA+blood+GUDCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.31	0.111	no	no	no	no	no	no	DM-DS
GCDCA+blood	PDGF-bb	GCDCA+blood+HCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.31	0.111	no	no	no	no	no	no	DM-DS
GCDCA+blood	PDGF-bb	GCDCA+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.31	0.111	no	no	no	no	no	no	DM-DS
ACA+blood	PDGF-bb	ACA+blood+EPA+blood+n3+blood-FGF basic+IL-17A-IL-1b-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.338	0.111	no	no	no	no	no	no	DM-DS
ACA+blood	PDGF-bb	ACA+blood-decanoic acid C10+blood-n3+blood-FGF basic+IL-17A-IL-1b-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.338	0.111	no	no	no	no	no	no	DM-DS
ACA+blood	PDGF-bb	ACA+blood+EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.338	0.111	no	no	no	no	no	no	DM-DS
DCA+stool	PDGF-bb	DCA+stool-GCA+stool+DPA+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.195	0.111	no	no	no	no	no	no	DM-DS
Butyric acid+stool	PDGF-bb	Butyric acid+stool-16:0/20:5-PC+blood+18:0/22:6-PA+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.102	0.111	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	PDGF-bb	Butyric acid+stool-16:0/20:5-PC+blood+d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.102	0.111	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	PDGF-bb	Butyric acid+stool+L-Citrulline+blood+L-Ornithine+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.102	0.111	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	PDGF-bb	Butyric acid+stool-16:0/20:5-PC+blood-L-Ornithine+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.102	0.111	dn	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	PDGF-bb	4-hydroxybenzoic acid+stool+TDCA+stool-12-ketoDCA+blood+Ethanolamine+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.111	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	PDGF-bb	4-hydroxybenzoic acid+stool+L-Tryptophan+stool+8-HETE+blood+Ethanolamine+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.111	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	PDGF-bb	4-hydroxybenzoic acid+stool+L-Tryptophan+stool+8-HETE+blood-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.111	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	PDGF-bb	4-hydroxybenzoic acid+stool-DCA+stool-GCA+stool+DPA+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.111	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	PDGF-bb	4-hydroxybenzoic acid+stool+L-Tryptophan+stool+L-Tyrosine+stool-nutriCA+stool-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.111	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	PDGF-bb	4-hydroxybenzoic acid+stool+L-Tryptophan+stool+8-HETE+blood+L-Ornithine+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.111	no	dn	no	no	no	no	DM-DS
Turicibacter	PDGF-bb	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-PDGF-bb	Indirect	Genus	serum_cytokines	0.269	0.111	no	no	no	no	no	no	DM-DS
Turicibacter	PDGF-bb	"Turicibacter+Desulfovibrio+Antigen processing and presentation-Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.269	0.111	no	no	no	no	no	no	DM-DS
GCA+blood	PDGF-bb	GCA+blood+HCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.16	0.111	no	no	no	no	no	no	DM-DS
GCA+blood	PDGF-bb	GCA+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.16	0.111	no	no	no	no	no	no	DM-DS
ACA+stool	PDGF-bb	ACA+stool-Kynurenic acid+stool-nutriCA+stool-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.417	0.111	no	no	no	no	no	no	DM-DS
CDCA+blood	PDGF-bb	CDCA+blood-Ethanolamine+blood+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.506	0.111	no	no	no	no	no	no	DM-DS
capric acid C6+blood	PDGF-bb	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.433	0.111	no	no	no	no	no	no	DM-DS
Prevotella	PDGF-bb	Prevotella+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	DM-DS
Prevotella	PDGF-bb	Prevotella-Glycolysis / Gluconeogenesis-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	DM-DS
Prevotella	PDGF-bb	Prevotella-20:3/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	DM-DS
Prevotella	PDGF-bb	"Prevotella+Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	DM-DS
Prevotella	PDGF-bb	Prevotella+Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	DM-DS
Prevotella	PDGF-bb	Prevotella+Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	DM-DS
Prevotella	PDGF-bb	Prevotella+Phospholipase D signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	DM-DS
iso-DCA+blood	PDGF-bb	iso-DCA+blood+L-Citrulline+blood+L-Ornithine+blood+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.38	0.111	no	no	no	no	no	no	DM-DS
HCA+stool	PDGF-bb	HCA+stool-HDCA+stool+L-Citrulline+blood+L-Ornithine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.155	0.111	no	no	no	no	no	no	DM-DS
Roseburia	PDGF-bb	Roseburia+Faecalibacterium+PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	PDGF-bb	12-ketoDCA+stool-GCA+stool+DPA+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.505	0.111	no	no	no	no	no	no	DM-DS
GLCA+blood	PDGF-bb	GLCA+blood-SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.319	0.111	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	PDGF-bb	L-Tryptophan+stool+8-HETE+blood+L-Ornithine+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.557	0.111	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	PDGF-bb	L-Tryptophan+stool+L-Tyrosine+stool-nutriCA+stool-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.557	0.111	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	PDGF-bb	L-Tryptophan+stool+8-HETE+blood-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.557	0.111	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	PDGF-bb	L-Tryptophan+stool+8-HETE+blood+Ethanolamine+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.557	0.111	no	no	no	no	no	no	DM-DS
CA+blood	PDGF-bb	CA+blood+CDCA+blood-Ethanolamine+blood+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.606	0.111	no	no	no	no	no	no	DM-DS
GUDCA+stool	PDGF-bb	GUDCA+stool+TUDCA+stool-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0085	0.111	no	dn	no	no	no	no	DM-DS
L-Phenylalanine+stool	PDGF-bb	L-Phenylalanine+stool-16:0/20:3-PC+blood+18:0/18:0-PC+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.398	0.111	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	PDGF-bb	L-Phenylalanine+stool+8-HETE+blood+Ethanolamine+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.398	0.111	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	PDGF-bb	L-Phenylalanine+stool-16:0/20:3-PC+blood+18:0/18:1-PC+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.398	0.111	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	PDGF-bb	L-Phenylalanine+stool+L-Tyrosine+stool-nutriCA+stool-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.398	0.111	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	PDGF-bb	L-Phenylalanine+stool+8-HETE+blood+L-Ornithine+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.398	0.111	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	PDGF-bb	L-Phenylalanine+stool+8-HETE+blood-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.398	0.111	no	no	no	no	no	no	DM-DS
butyric acid C4+blood	PDGF-bb	butyric acid C4+blood+L-Ornithine+blood+PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.407	0.111	no	no	no	no	no	no	DM-DS
GCA+stool	PDGF-bb	GCA+stool+DPA+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0809	0.111	no	no	no	no	no	no	DM-DS
Coprococcus	PDGF-bb	Coprococcus+TUDCA+stool-d18:1-14:0-SM+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.612	0.111	no	no	no	no	no	no	DM-DS
Coprococcus	PDGF-bb	Coprococcus+Roseburia+Faecalibacterium+PDGF-bb	Indirect	Genus	serum_cytokines	0.612	0.111	no	no	no	no	no	no	DM-DS
Coprococcus	PDGF-bb	Coprococcus+16:0/16:0-PC+blood+18:0/22:6-PA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.612	0.111	no	no	no	no	no	no	DM-DS
Coprococcus	PDGF-bb	Coprococcus-14:0/18:2-PC+blood-L-Ornithine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.612	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+JAK-STAT signaling pathway+DPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Dopaminergic synapse-DPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Morphine addiction-DPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Retrograde endocannabinoid signaling-DPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Renin secretion-DPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Vascular smooth muscle contraction-DPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Thyroid hormone synthesis-DPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Circadian entrainment-DPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Pancreatic secretion-DPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	"Oscillospira-Parathyroid hormone synthesis, secretion and action-DPA+blood+PDGF-bb"	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Calcium signaling pathway-16:1/16:1-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Calcium signaling pathway-18:0/22:6-PA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+JAK-STAT signaling pathway+Relaxin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Autophagy - animal+Relaxin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+NF-kappa B signaling pathway+Relaxin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Focal adhesion-Relaxin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	"Oscillospira+JAK-STAT signaling pathway+Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	"Oscillospira+Platinum drug resistance+Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	"Oscillospira+Autophagy - animal+Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	"Oscillospira+NF-kappa B signaling pathway+Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	"Oscillospira+FoxO signaling pathway+Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	"Oscillospira-Focal adhesion-Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Calcium signaling pathway+Long-term depression+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+MAPK signaling pathway-Long-term depression+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+JAK-STAT signaling pathway-Hematopoietic cell lineage-PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Autophagy - animal-Hematopoietic cell lineage-PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+NF-kappa B signaling pathway-Hematopoietic cell lineage-PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Focal adhesion+Hematopoietic cell lineage-PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Renin secretion-Ethanolamine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Hepatitis B+Ethanolamine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Inflammatory mediator regulation of TRP channels-Ethanolamine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+T cell receptor signaling pathway+Ethanolamine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+NF-kappa B signaling pathway+Ethanolamine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Focal adhesion-Ethanolamine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+JAK-STAT signaling pathway+Neurotrophin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Vascular smooth muscle contraction-Neurotrophin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+T cell receptor signaling pathway+Neurotrophin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Platelet activation-Neurotrophin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Autophagy - animal+Neurotrophin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Circadian entrainment-Neurotrophin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+NF-kappa B signaling pathway+Neurotrophin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Focal adhesion-Neurotrophin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Vibrio cholerae infection-L-Ornithine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Platelet activation-L-Ornithine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Focal adhesion-L-Ornithine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Autophagy - animal+Cytosolic DNA-sensing pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+NF-kappa B signaling pathway+Cytosolic DNA-sensing pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Focal adhesion-Cytosolic DNA-sensing pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Ribosome-Phospholipase D signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Oxidative phosphorylation-Phospholipase D signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+NF-kappa B signaling pathway+Phospholipase D signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+FoxO signaling pathway+Phospholipase D signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Ribosome-C-type lectin receptor signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Vascular smooth muscle contraction-C-type lectin receptor signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Platelet activation-C-type lectin receptor signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Oxidative phosphorylation-C-type lectin receptor signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Autophagy - animal+C-type lectin receptor signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+NF-kappa B signaling pathway+C-type lectin receptor signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Cardiac muscle contraction-C-type lectin receptor signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+FoxO signaling pathway+C-type lectin receptor signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Focal adhesion-C-type lectin receptor signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Thermogenesis-Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+JAK-STAT signaling pathway+Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Ribosome-Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Dopaminergic synapse-Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Retrograde endocannabinoid signaling-Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Melanogenesis-Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Inflammatory mediator regulation of TRP channels-Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Vascular smooth muscle contraction-Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+T cell receptor signaling pathway+Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Platelet activation-Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Oxidative phosphorylation-Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Autophagy - animal+Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Circadian entrainment-Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+NF-kappa B signaling pathway+Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Cardiac muscle contraction-Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+FoxO signaling pathway+Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Focal adhesion-Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Thermogenesis-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+JAK-STAT signaling pathway+Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Ribosome-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Prion disease-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Huntington disease-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Alzheimer disease-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Retrograde endocannabinoid signaling-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Renin secretion-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Melanogenesis-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Inflammatory mediator regulation of TRP channels-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Oxidative phosphorylation-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Autophagy - animal+Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Non-alcoholic fatty liver disease-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+NF-kappa B signaling pathway+Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Pathways of neurodegeneration - multiple diseases-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Cardiac muscle contraction-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Parkinson disease-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Thermogenesis-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+JAK-STAT signaling pathway+Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Vibrio cholerae infection-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Prion disease-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Dopaminergic synapse-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Retrograde endocannabinoid signaling-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Renin secretion-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Hepatitis B+Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Vasopressin-regulated water reabsorption-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Melanogenesis-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Inflammatory mediator regulation of TRP channels-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Salivary secretion-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Vascular smooth muscle contraction-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+T cell receptor signaling pathway+Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Platelet activation-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Oxidative phosphorylation-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Gastric acid secretion-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Autophagy - animal+Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Circadian entrainment-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+NF-kappa B signaling pathway+Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Focal adhesion-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+JAK-STAT signaling pathway+TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Ribosome-TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Vascular smooth muscle contraction-TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+T cell receptor signaling pathway+TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Platelet activation-TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Oxidative phosphorylation-TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Autophagy - animal+TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+NF-kappa B signaling pathway+TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Cardiac muscle contraction-TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+FoxO signaling pathway+TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Focal adhesion-TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Thermogenesis-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+JAK-STAT signaling pathway+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Vibrio cholerae infection-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Ribosome-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Prion disease-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Huntington disease-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Alzheimer disease-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Dopaminergic synapse-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Platinum drug resistance+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Coronavirus disease - COVID-19-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Retrograde endocannabinoid signaling-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Renin secretion-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Hepatitis B+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Rap1 signaling pathway-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Vasopressin-regulated water reabsorption-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Melanogenesis-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Inflammatory mediator regulation of TRP channels-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Shigellosis-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Salivary secretion-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Vascular smooth muscle contraction-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+T cell receptor signaling pathway+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+MAPK signaling pathway+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Platelet activation-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Oxidative phosphorylation-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Gastric acid secretion-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Autophagy - animal+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Endocrine and other factor-regulated calcium reabsorption-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Non-alcoholic fatty liver disease-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Circadian entrainment-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+NF-kappa B signaling pathway+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Pathways of neurodegeneration - multiple diseases-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Pancreatic secretion-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Cardiac muscle contraction-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+FoxO signaling pathway+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Parkinson disease-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Focal adhesion-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	"Oscillospira-Parathyroid hormone synthesis, secretion and action-Transcriptional misregulation in cancer+PDGF-bb"	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+JAK-STAT signaling pathway+Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Vibrio cholerae infection-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Dopaminergic synapse-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Retrograde endocannabinoid signaling-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Renin secretion-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Hepatitis B+Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Inflammatory mediator regulation of TRP channels-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Salivary secretion-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Vascular smooth muscle contraction-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+T cell receptor signaling pathway+Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Platelet activation-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Gastric acid secretion-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Autophagy - animal+Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Circadian entrainment-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+NF-kappa B signaling pathway+Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Focal adhesion-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+JAK-STAT signaling pathway+Adipocytokine signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+T cell receptor signaling pathway+Adipocytokine signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Platelet activation-Adipocytokine signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Autophagy - animal+Adipocytokine signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Circadian entrainment-Adipocytokine signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+NF-kappa B signaling pathway+Adipocytokine signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Focal adhesion-Adipocytokine signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Thermogenesis-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+JAK-STAT signaling pathway+Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Vibrio cholerae infection-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Ribosome-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Prion disease-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Huntington disease-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Alzheimer disease-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Dopaminergic synapse-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Retrograde endocannabinoid signaling-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Renin secretion-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Melanogenesis-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Inflammatory mediator regulation of TRP channels-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Vascular smooth muscle contraction-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+T cell receptor signaling pathway+Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Platelet activation-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Oxidative phosphorylation-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Gastric acid secretion-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Autophagy - animal+Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Circadian entrainment-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+NF-kappa B signaling pathway+Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Cardiac muscle contraction-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+FoxO signaling pathway+Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Focal adhesion-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Platinum drug resistance+Primary immunodeficiency-PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Progesterone-mediated oocyte maturation+Primary immunodeficiency-PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Human cytomegalovirus infection-Primary immunodeficiency-PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira-Rap1 signaling pathway-Primary immunodeficiency-PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+Spliceosome+Primary immunodeficiency-PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
Oscillospira	PDGF-bb	Oscillospira+MAPK signaling pathway+Primary immunodeficiency-PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-DS
HCA+blood	PDGF-bb	HCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.544	0.111	no	no	no	no	no	no	DM-DS
iso-LCA+stool	PDGF-bb	iso-LCA+stool-TCA+stool-16:0/22:6-PC+blood+16:1/16:1-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-DS
iso-LCA+stool	PDGF-bb	iso-LCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:0/18:1-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-DS
iso-LCA+stool	PDGF-bb	iso-LCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:0/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-DS
iso-LCA+stool	PDGF-bb	iso-LCA+stool-TDCA+stool-12-ketoDCA+blood+Ethanolamine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-DS
iso-LCA+stool	PDGF-bb	iso-LCA+stool-TCA+stool+18:0/18:1-PE+blood-Ethanolamine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-DS
iso-LCA+stool	PDGF-bb	iso-LCA+stool-TCA+stool-18:1/20:4-PC+blood+20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-DS
iso-LCA+stool	PDGF-bb	iso-LCA+stool-TCA+stool-20:0/20:5-PC+blood+20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-DS
iso-LCA+stool	PDGF-bb	iso-LCA+stool-TCA+stool-16:0/22:6-PC+blood+20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-DS
iso-LCA+stool	PDGF-bb	iso-LCA+stool-TCA+stool+18:0/18:1-PE+blood-20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-DS
iso-LCA+stool	PDGF-bb	iso-LCA+stool-TCA+stool-18:0/20:4-PC+blood+20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-DS
iso-LCA+stool	PDGF-bb	iso-LCA+stool-TCA+stool-20:0/20:5-PC+blood+d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-DS
iso-LCA+stool	PDGF-bb	iso-LCA+stool-TCA+stool+20:2+blood-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-DS
iso-LCA+stool	PDGF-bb	iso-LCA+stool+T-¦Á-MCA+stool+TUDCA+stool-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-DS
DCA+blood	PDGF-bb	DCA+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.122	0.111	no	no	no	no	no	no	DM-DS
DCA+blood	PDGF-bb	DCA+blood+nutriCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.122	0.111	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	PDGF-bb	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.33	0.111	no	no	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	PDGF-bb	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF+IL-13-PDGF-bb"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.111	up	up	no	no	no	no	DM-DS
nutriCA+blood	PDGF-bb	nutriCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.726	0.111	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	PDGF-bb	Indole-3-Acetic acid+stool-nutriCA+stool-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.304	0.111	no	no	no	no	no	no	DM-DS
TCA+stool	PDGF-bb	TCA+stool-18:1/20:4-PC+blood+20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	DM-DS
TCA+stool	PDGF-bb	TCA+stool-20:0/20:5-PC+blood+20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	DM-DS
TCA+stool	PDGF-bb	TCA+stool+18:0/18:1-PE+blood-20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	DM-DS
TCA+stool	PDGF-bb	TCA+stool-16:0/22:6-PC+blood+20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	DM-DS
TCA+stool	PDGF-bb	TCA+stool-18:0/20:4-PC+blood+20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	DM-DS
TCA+stool	PDGF-bb	TCA+stool+18:0/18:1-PE+blood-Ethanolamine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	DM-DS
TCA+stool	PDGF-bb	TCA+stool-16:0/22:6-PC+blood+16:1/16:1-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	DM-DS
TCA+stool	PDGF-bb	TCA+stool-20:0/20:5-PC+blood+d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	DM-DS
TCA+stool	PDGF-bb	TCA+stool+20:2+blood-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	DM-DS
HDCA+stool	PDGF-bb	HDCA+stool+L-Citrulline+blood+L-Ornithine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.176	0.111	no	no	no	no	no	no	DM-DS
Lachnospira	PDGF-bb	Lachnospira-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-DS
Lachnospira	PDGF-bb	Lachnospira-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-DS
Lachnospira	PDGF-bb	Lachnospira+Glycolysis / Gluconeogenesis-PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-DS
Lachnospira	PDGF-bb	Lachnospira-Cytosolic DNA-sensing pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-DS
Lachnospira	PDGF-bb	Lachnospira-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-DS
Lachnospira	PDGF-bb	Lachnospira-TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-DS
Fusobacterium	PDGF-bb	Fusobacterium-18:0/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-DS
Fusobacterium	PDGF-bb	Fusobacterium-18:0/18:1-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-DS
GCDCA+stool	PDGF-bb	GCDCA+stool+16:0/16:1-PC+blood+18:0/18:1-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-DS
GCDCA+stool	PDGF-bb	GCDCA+stool+16:0/20:3-PC+blood+18:0/18:1-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-DS
GCDCA+stool	PDGF-bb	GCDCA+stool+16:0/16:1-PC+blood+18:0/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-DS
GCDCA+stool	PDGF-bb	GCDCA+stool+16:0/20:3-PC+blood+18:0/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-DS
GCDCA+stool	PDGF-bb	GCDCA+stool+16:0/18:1-PC+blood+20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-DS
GCDCA+stool	PDGF-bb	GCDCA+stool+18:1/16:0-PC+blood-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-DS
GCDCA+stool	PDGF-bb	GCDCA+stool+16:0/18:2-PC+blood-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-DS
GCDCA+stool	PDGF-bb	GCDCA+stool+Cystine+blood-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-DS
GCDCA+stool	PDGF-bb	GCDCA+stool+16:0/18:1-PC+blood+18:0/22:6-PA+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-DS
GCDCA+stool	PDGF-bb	GCDCA+stool-Isobutyric acid+stool-nutriCA+stool-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-DS
GCDCA+stool	PDGF-bb	GCDCA+stool-Indole-3-Acetic acid+stool-nutriCA+stool-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	PDGF-bb	5-Hydroxytryptamine+stool-nutriCA+stool-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.111	dn	dn	no	no	no	no	DM-DS
Odoribacter	PDGF-bb	Odoribacter+Glycolysis / Gluconeogenesis-PDGF-bb	Indirect	Genus	serum_cytokines	0.798	0.111	no	no	no	no	no	no	DM-DS
Odoribacter	PDGF-bb	"Odoribacter-Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.798	0.111	no	no	no	no	no	no	DM-DS
Odoribacter	PDGF-bb	Odoribacter-Long-term depression+PDGF-bb	Indirect	Genus	serum_cytokines	0.798	0.111	no	no	no	no	no	no	DM-DS
Actinomyces	PDGF-bb	Actinomyces+Coprococcus+TUDCA+stool-d18:1-14:0-SM+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.621	0.111	no	no	no	no	no	no	DM-DS
Actinomyces	PDGF-bb	Actinomyces+Coprococcus+Roseburia+Faecalibacterium+PDGF-bb	Indirect	Genus	serum_cytokines	0.621	0.111	no	no	no	no	no	no	DM-DS
Actinomyces	PDGF-bb	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:0/22:6-PA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.621	0.111	no	no	no	no	no	no	DM-DS
Actinomyces	PDGF-bb	Actinomyces+Coprococcus-14:0/18:2-PC+blood-L-Ornithine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.621	0.111	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	PDGF-bb	Isobutyric acid+stool-nutriCA+stool-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.408	0.111	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	PDGF-bb	"2-hydroxyphenylacetic acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF+IL-13-PDGF-bb"	Indirect	urine_cometabolism	serum_cytokines	0.763	0.111	no	no	no	no	no	no	DM-DS
Kynurenic acid+stool	PDGF-bb	Kynurenic acid+stool-nutriCA+stool-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.037	0.111	dn	dn	no	no	no	no	DM-DS
Caproic acid+stool	PDGF-bb	Caproic acid+stool+Indole-3-Acetic acid+stool-nutriCA+stool-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.882	0.111	no	no	no	no	no	no	DM-DS
Caproic acid+stool	PDGF-bb	Caproic acid+stool-GCA+stool+DPA+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.882	0.111	no	no	no	no	no	no	DM-DS
Eggerthella	PDGF-bb	Eggerthella+nutriCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.912	0.111	no	no	no	no	no	no	DM-DS
Anaerotruncus	PDGF-bb	Anaerotruncus-Ruminococcus-PDGF-bb	Indirect	Genus	serum_cytokines	0.904	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes+RNA degradation-TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes-Neutrophil extracellular trap formation+Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes+RNA degradation-Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes-Alcoholism+Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes-Neutrophil extracellular trap formation+Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes+RNA degradation-Amoebiasis+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes-Oxytocin signaling pathway-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes+RNA degradation-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes-Rap1 signaling pathway-Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes-Oxytocin signaling pathway-Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes+Spliceosome+Primary immunodeficiency-PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes-Rap1 signaling pathway-Primary immunodeficiency-PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes-Alcoholism-d18:1-14:0-SM+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes+RNA degradation+d18:1-14:0-SM+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes-Neutrophil extracellular trap formation+C-type lectin receptor signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes+RNA degradation-C-type lectin receptor signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes+RNA degradation-Adipocytokine signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes-Oxytocin signaling pathway-Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes+RNA degradation-Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
Anaerostipes	PDGF-bb	Anaerostipes+RNA degradation-Phospholipase D signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-DS
TUDCA+stool	PDGF-bb	TUDCA+stool-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.241	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/16:1-PC+blood+18:0/18:1-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+L-Phenylalanine+stool-16:0/20:3-PC+blood+18:0/18:1-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/20:3-PC+blood+18:0/18:1-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool-UDCA+stool+16:0/20:3-PC+blood+18:0/18:1-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/16:1-PC+blood+18:0/18:0-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+L-Phenylalanine+stool-16:0/20:3-PC+blood+18:0/18:0-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/20:3-PC+blood+18:0/18:0-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool-UDCA+stool+16:0/20:3-PC+blood+18:0/18:0-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+Phenylacetic acid+stool-18:0/16:0-PC+blood+20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/18:1-PC+blood+20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+Phenylacetic acid+stool-14:0+blood-20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+L-Phenylalanine+stool+8-HETE+blood+L-Ornithine+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/18:1-PC+blood+18:0/22:6-PA+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/18:2-PC+blood-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+L-Phenylalanine+stool+8-HETE+blood-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+Phenylacetic acid+stool-18:1/16:0-PC+blood-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+Phenylacetic acid+stool-Cystine+blood-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+L-Phenylalanine+stool+8-HETE+blood+Ethanolamine+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+L-Phenylalanine+stool+L-Tyrosine+stool-nutriCA+stool-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-DS
Paraprevotella	PDGF-bb	Paraprevotella-Adipocytokine signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	PDGF-bb	¦Ø-MCA+stool-L-Tyrosine+stool-nutriCA+stool-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.919	0.111	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	PDGF-bb	¦Ø-MCA+stool-Isobutyric acid+stool-nutriCA+stool-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.919	0.111	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	PDGF-bb	¦Ø-MCA+stool+CDCA+stool+nutriCA+stool-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.919	0.111	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	PDGF-bb	Phenylacetic acid+stool-14:0+blood-20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.785	0.111	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	PDGF-bb	Phenylacetic acid+stool-16:0/18:1-PC+blood+20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.785	0.111	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	PDGF-bb	Phenylacetic acid+stool-18:0/16:0-PC+blood+20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.785	0.111	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	PDGF-bb	Phenylacetic acid+stool-16:0/20:3-PC+blood+18:0/18:0-PC+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.785	0.111	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	PDGF-bb	Phenylacetic acid+stool-16:0/16:1-PC+blood+18:0/18:0-PC+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.785	0.111	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	PDGF-bb	Phenylacetic acid+stool-16:0/18:2-PC+blood-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.785	0.111	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	PDGF-bb	Phenylacetic acid+stool-18:1/16:0-PC+blood-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.785	0.111	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	PDGF-bb	Phenylacetic acid+stool-Cystine+blood-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.785	0.111	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	PDGF-bb	Phenylacetic acid+stool-16:0/20:3-PC+blood+18:0/18:1-PC+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.785	0.111	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	PDGF-bb	Phenylacetic acid+stool-16:0/16:1-PC+blood+18:0/18:1-PC+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.785	0.111	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	PDGF-bb	Phenylacetic acid+stool-16:0/18:1-PC+blood+18:0/22:6-PA+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.785	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+Pathways in cancer+Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+ErbB signaling pathway+Chronic myeloid leukemia+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+ErbB signaling pathway+Neurotrophin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+Pathways in cancer+Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+ErbB signaling pathway+Prostate cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+ErbB signaling pathway+Phospholipase D signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+ErbB signaling pathway+Prolactin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+ErbB signaling pathway+Relaxin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+Signaling pathways regulating pluripotency of stem cells+TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+ErbB signaling pathway+TNF signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	"Gemmiger+Signaling pathways regulating pluripotency of stem cells+Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	"Gemmiger+ErbB signaling pathway+Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+Colorectal cancer+d18:1-14:0-SM+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+Central carbon metabolism in cancer+d18:1-14:0-SM+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+Central carbon metabolism in cancer+nutriCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+Signaling pathways regulating pluripotency of stem cells-16:1/16:1-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+Colorectal cancer-16:1/16:1-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+Gastric cancer-16:1/16:1-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+Pathways in cancer+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+ErbB signaling pathway+Transcriptional misregulation in cancer+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+ErbB signaling pathway+Chagas disease+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
Gemmiger	PDGF-bb	Gemmiger+ErbB signaling pathway+C-type lectin receptor signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-DS
GDCA+stool	PDGF-bb	GDCA+stool+16:0/18:1-PC+blood+20:3/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.656	0.111	no	no	no	no	no	no	DM-DS
GDCA+stool	PDGF-bb	GDCA+stool+16:0/20:3-PC+blood+18:0/18:1-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.656	0.111	no	no	no	no	no	no	DM-DS
GDCA+stool	PDGF-bb	GDCA+stool+16:0/20:3-PC+blood+18:0/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.656	0.111	no	no	no	no	no	no	DM-DS
GDCA+stool	PDGF-bb	GDCA+stool+16:0/18:1-PC+blood+18:0/22:6-PA+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.656	0.111	no	no	no	no	no	no	DM-DS
GDCA+stool	PDGF-bb	GDCA+stool-Indole-3-Acetic acid+stool-nutriCA+stool-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.656	0.111	no	no	no	no	no	no	DM-DS
GDCA+stool	PDGF-bb	GDCA+stool-Isobutyric acid+stool-nutriCA+stool-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.656	0.111	no	no	no	no	no	no	DM-DS
Methanobrevibacter	PDGF-bb	Methanobrevibacter+d18:1-14:0-SM+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.629	0.111	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	PDGF-bb	L-Tyrosine+stool-nutriCA+stool-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.44	0.111	no	no	no	no	no	no	DM-DS
CDCA+stool	PDGF-bb	CDCA+stool+nutriCA+stool-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.663	0.111	no	no	no	no	no	no	DM-DS
CA+stool	PDGF-bb	CA+stool+nutriCA+stool-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	DM-DS
HDCA+blood	PDGF-bb	HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+L-Ornithine+blood+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.483	0.111	no	no	no	no	no	no	DM-DS
UDCA+stool	PDGF-bb	UDCA+stool+16:0/20:3-PC+blood+18:0/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.266	0.111	no	no	no	no	no	no	DM-DS
UDCA+stool	PDGF-bb	UDCA+stool+16:0/20:3-PC+blood+18:0/18:1-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.266	0.111	no	no	no	no	no	no	DM-DS
TDCA+stool	PDGF-bb	TDCA+stool-12-ketoDCA+blood+Ethanolamine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.963	0.111	no	no	no	no	no	no	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	PDGF-bb	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-PDGF-bb	Indirect	urine_cometabolism	serum_cytokines	0.973	0.111	no	no	no	no	no	no	DM-DS
Desulfovibrio	PDGF-bb	Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-PDGF-bb	Indirect	Genus	serum_cytokines	0.27	0.111	no	no	no	no	no	no	DM-DS
Desulfovibrio	PDGF-bb	"Desulfovibrio+Antigen processing and presentation-Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.27	0.111	no	no	no	no	no	no	DM-DS
nutriCA+stool	PDGF-bb	nutriCA+stool-PDGF-bb	Direct	stool_bileacids	serum_cytokines	0.481	0.111	no	no	no	no	no	no	DM-DS
Bilophila	PDGF-bb	Bilophila+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-PDGF-bb	Indirect	Genus	serum_cytokines	0.528	0.111	no	no	no	no	no	no	DM-DS
Bilophila	PDGF-bb	"Bilophila+Desulfovibrio+Antigen processing and presentation-Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.528	0.111	no	no	no	no	no	no	DM-DS
GDCA+blood	PDGF-bb	GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+L-Ornithine+blood+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.632	0.111	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	PDGF-bb	P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	urine_cometabolism	serum_cytokines	0.436	0.111	no	no	no	no	no	no	DM-DS
acetic acid C2+blood	PDGF-bb	acetic acid C2+blood+d18:1-22:1-SM+blood+HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+L-Ornithine+blood+PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.000193	0.111	up	dn	no	no	no	no	DM-DS
acetic acid C2+blood	PDGF-bb	acetic acid C2+blood+d18:1-20:1-SM+blood+HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+L-Ornithine+blood+PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.000193	0.111	up	dn	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	PDGF-bb	isovaleric acid iso-C5+blood+n3+blood-FGF basic+IL-17A-IL-1b-PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.117	0.111	no	no	no	no	no	no	DM-DS
Clostridium	PDGF-bb	Clostridium-Adipocytokine signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.925	0.111	no	no	no	no	no	no	DM-DS
Clostridium	PDGF-bb	Clostridium-Long-term depression+PDGF-bb	Indirect	Genus	serum_cytokines	0.925	0.111	no	no	no	no	no	no	DM-DS
Clostridium	PDGF-bb	Clostridium-Ethanolamine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.925	0.111	no	no	no	no	no	no	DM-DS
Clostridium	PDGF-bb	Clostridium+nutriCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.925	0.111	no	no	no	no	no	no	DM-DS
Clostridium	PDGF-bb	Clostridium-Phospholipase D signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.925	0.111	no	no	no	no	no	no	DM-DS
Clostridium	PDGF-bb	Clostridium-Relaxin signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.925	0.111	no	no	no	no	no	no	DM-DS
Clostridium	PDGF-bb	Clostridium+Glycolysis / Gluconeogenesis-PDGF-bb	Indirect	Genus	serum_cytokines	0.925	0.111	no	no	no	no	no	no	DM-DS
Clostridium	PDGF-bb	Clostridium+Hematopoietic cell lineage-PDGF-bb	Indirect	Genus	serum_cytokines	0.925	0.111	no	no	no	no	no	no	DM-DS
Clostridium	PDGF-bb	Clostridium-cAMP signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.925	0.111	no	no	no	no	no	no	DM-DS
Clostridium	PDGF-bb	"Clostridium-Growth hormone synthesis, secretion and action+PDGF-bb"	Indirect	Genus	serum_cytokines	0.925	0.111	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	PDGF-bb	T-¦Á-MCA+stool+TUDCA+stool-d18:1-14:0-SM+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.48	0.111	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	PDGF-bb	12-ketoDCA+blood+Ethanolamine+blood+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.517	0.111	no	no	no	no	no	no	DM-DS
Butyricicoccus	PDGF-bb	Butyricicoccus+TUDCA+stool-d18:1-14:0-SM+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.852	0.111	no	no	no	no	no	no	DM-DS
Blautia	IL-8	Blautia+Dorea-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-DS
Blautia	IL-8	Blautia-Cocaine addiction-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-DS
Blautia	IL-8	Blautia+UDCA+stool+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-DS
Blautia	IL-8	Blautia-Thyroid hormone synthesis-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-DS
Blautia	IL-8	Blautia-TDCA+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-DS
Blautia	IL-8	Blautia+CDCA+stool+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-DS
Blautia	IL-8	Blautia-Calcium signaling pathway-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-DS
Blautia	IL-8	Blautia+GCA+stool+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-DS
Blautia	IL-8	Blautia+Longevity regulating pathway - multiple species+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-DS
Parabacteroides	IL-8	Parabacteroides-16:0/18:2-PI+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-DS
Parabacteroides	IL-8	Parabacteroides-L-Alanine+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-DS
Parabacteroides	IL-8	Parabacteroides-16:0/18:2-PI+blood-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-DS
Parabacteroides	IL-8	Parabacteroides+Alistipes-IL-6+IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-DS
Parabacteroides	IL-8	Parabacteroides+MAPK signaling pathway-IL-6+IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-DS
Dorea	IL-8	Dorea-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	DM-DS
Faecalibacterium	IL-8	Faecalibacterium+L-Alanine+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.0039	0.579	no	dn	dn	no	no	no	DM-DS
Bacteroides	IL-8	"Bacteroides-Growth hormone synthesis, secretion and action-IL-1ra+IL-8"	Indirect	Genus	serum_cytokines	0.000267	0.579	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-8	Bacteroides+Longevity regulating pathway - multiple species+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.000267	0.579	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-8	Bacteroides-Long-term depression-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.000267	0.579	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-8	Bacteroides-Pathways in cancer-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.000267	0.579	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-8	Bacteroides+Leishmaniasis+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.000267	0.579	dn	dn	up	no	no	no	DM-DS
Propionic acid+stool	IL-8	Propionic acid+stool+P-hydroxyhippuric acid+urine-IL-1ra+IL-8	Indirect	stool_scfa	serum_cytokines	0.0436	0.579	dn	no	up	no	no	no	DM-DS
Propionic acid+stool	IL-8	Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-8	Indirect	stool_scfa	serum_cytokines	0.0436	0.579	dn	no	up	no	no	no	DM-DS
[Ruminococcus]	IL-8	[Ruminococcus]-18:2/20:4-PC+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-8	[Ruminococcus]+16:0/18:2-PI+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-8	[Ruminococcus]+Tight junction+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-8	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-8	[Ruminococcus]-FoxO signaling pathway-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-8	[Ruminococcus]-Progesterone-mediated oocyte maturation-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-8	[Ruminococcus]-ErbB signaling pathway-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-8	[Ruminococcus]-JAK-STAT signaling pathway-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-8	[Ruminococcus]-Gastric cancer-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-8	[Ruminococcus]-Platinum drug resistance-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-8	[Ruminococcus]-Pathways in cancer-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-8	[Ruminococcus]-Non-small cell lung cancer-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-8	[Ruminococcus]-Pancreatic cancer-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-8	[Ruminococcus]-Progesterone-mediated oocyte maturation+Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-8	[Ruminococcus]+16:0/18:2-PI+blood-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	DM-DS
GUDCA+blood	IL-8	GUDCA+blood+UDCA+blood+Eotaxin-IL-8	Indirect	serum_bileacids	serum_cytokines	0.0766	0.579	no	no	dn	no	no	no	DM-DS
UDCA+blood	IL-8	UDCA+blood+Eotaxin-IL-8	Indirect	serum_bileacids	serum_cytokines	0.0939	0.579	no	no	dn	no	no	no	DM-DS
Acetic acid+stool	IL-8	Acetic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-8	Indirect	stool_scfa	serum_cytokines	0.0656	0.579	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	IL-8	Acetic acid+stool+P-hydroxyhippuric acid+urine-IL-1ra+IL-8	Indirect	stool_scfa	serum_cytokines	0.0656	0.579	dn	no	no	no	no	no	DM-DS
Alistipes	IL-8	Alistipes-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	DM-DS
Butyricimonas	IL-8	Butyricimonas-iso-DCA+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.17	0.579	no	no	no	no	no	no	DM-DS
Collinsella	IL-8	Collinsella-GnRH signaling pathway-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-DS
Collinsella	IL-8	Collinsella-Endocrine and other factor-regulated calcium reabsorption-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-DS
Collinsella	IL-8	Collinsella-18:2/20:4-PC+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-DS
5-Hydroxytryptamine+urine	IL-8	5-Hydroxytryptamine+urine-Hippuric acid+urine-IL-6+IL-8	Indirect	urine_cometabolism	serum_cytokines	0.171	0.579	no	no	no	no	no	no	DM-DS
Sarcina	IL-8	Sarcina-Glucagon signaling pathway-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.0703	0.579	no	no	no	no	no	no	DM-DS
Sarcina	IL-8	Sarcina-GnRH signaling pathway-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.0703	0.579	no	no	no	no	no	no	DM-DS
Sarcina	IL-8	Sarcina-Aldosterone synthesis and secretion-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.0703	0.579	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-8	Methanosphaera-Roseburia+16:0/18:2-PI+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.0703	0.579	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-8	Methanosphaera-Roseburia+16:0/18:2-PI+blood-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.0703	0.579	no	no	no	no	no	no	DM-DS
iso-DCA+stool	IL-8	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.155	0.579	no	no	no	no	no	no	DM-DS
iso-DCA+stool	IL-8	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-8	Indirect	stool_bileacids	serum_cytokines	0.155	0.579	no	no	no	no	no	no	DM-DS
LCA+stool	IL-8	LCA+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	DM-DS
Akkermansia	IL-8	Akkermansia+P-hydroxyhippuric acid+urine-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	DM-DS
Akkermansia	IL-8	Akkermansia+P-hydroxyhippuric acid+urine+Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	DM-DS
Bifidobacterium	IL-8	Bifidobacterium+Leukocyte transendothelial migration-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.105	0.579	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-8	Bifidobacterium+Vibrio cholerae infection+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.105	0.579	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-8	Bifidobacterium-FoxO signaling pathway-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.105	0.579	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-8	Bifidobacterium+Tight junction+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.105	0.579	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-8	Bifidobacterium+Bacterial invasion of epithelial cells+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.105	0.579	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-8	Bifidobacterium+Focal adhesion+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.105	0.579	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-8	Bifidobacterium+Leukocyte transendothelial migration+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.105	0.579	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-8	Bifidobacterium+Adherens junction+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.105	0.579	no	dn	no	no	no	no	DM-DS
3-Hydroxytyramine hydrochloride+urine	IL-8	3-Hydroxytyramine hydrochloride+urine-Hippuric acid+urine-IL-6+IL-8	Indirect	urine_cometabolism	serum_cytokines	0.288	0.579	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-8	Ruminococcus+18:0/18:0-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-DS
GCDCA+blood	IL-8	GCDCA+blood+L-Alanine+blood-IL-1ra+IL-8	Indirect	serum_bileacids	serum_cytokines	0.31	0.579	no	no	no	no	no	no	DM-DS
ACA+blood	IL-8	ACA+blood+EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin-IL-8	Indirect	serum_bileacids	serum_cytokines	0.338	0.579	no	no	no	no	no	no	DM-DS
DCA+stool	IL-8	DCA+stool+iso-LCA+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-DS
DCA+stool	IL-8	DCA+stool+HDCA+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-DS
DCA+stool	IL-8	DCA+stool+LCA+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-DS
DCA+stool	IL-8	DCA+stool-GCA+stool+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-DS
DCA+stool	IL-8	DCA+stool+HDCA+stool+Eotaxin-IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-DS
Hippuric acid+urine	IL-8	Hippuric acid+urine-IL-6+IL-8	Indirect	urine_cometabolism	serum_cytokines	0.361	0.579	no	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-8	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-8	Indirect	stool_scfa	serum_cytokines	0.102	0.579	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-8	Butyric acid+stool+L-Citrulline+blood+Eotaxin-IL-8	Indirect	stool_scfa	serum_cytokines	0.102	0.579	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-8	Butyric acid+stool+P-hydroxyhippuric acid+urine-IL-1ra+IL-8	Indirect	stool_scfa	serum_cytokines	0.102	0.579	dn	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	IL-8	4-hydroxybenzoic acid+stool-LCA+stool-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.579	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	IL-8	4-hydroxybenzoic acid+stool-iso-LCA+stool-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.579	no	dn	no	no	no	no	DM-DS
Turicibacter	IL-8	Turicibacter+Desulfovibrio+Antigen processing and presentation+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.269	0.579	no	no	no	no	no	no	DM-DS
GCA+blood	IL-8	GCA+blood+TDCA+blood-IL-1ra+IL-8	Indirect	serum_bileacids	serum_cytokines	0.16	0.579	no	no	no	no	no	no	DM-DS
ACA+stool	IL-8	ACA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-IL-8	Indirect	stool_bileacids	serum_cytokines	0.417	0.579	no	no	no	no	no	no	DM-DS
CDCA+blood	IL-8	CDCA+blood+UDCA+blood+Eotaxin-IL-8	Indirect	serum_bileacids	serum_cytokines	0.506	0.579	no	no	no	no	no	no	DM-DS
capric acid C6+blood	IL-8	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin-IL-8	Indirect	serum_scfa	serum_cytokines	0.433	0.579	no	no	no	no	no	no	DM-DS
Prevotella	IL-8	Prevotella+TDCA+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	DM-DS
Prevotella	IL-8	Prevotella+GDCA+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	DM-DS
Prevotella	IL-8	"Prevotella+Growth hormone synthesis, secretion and action-IL-1ra+IL-8"	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	DM-DS
Prevotella	IL-8	Prevotella+Endocrine resistance-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	DM-DS
Prevotella	IL-8	Prevotella-Tight junction+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	DM-DS
Prevotella	IL-8	Prevotella-Bacterial invasion of epithelial cells+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	DM-DS
Prevotella	IL-8	Prevotella+FoxO signaling pathway-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	DM-DS
Prevotella	IL-8	Prevotella+Hippuric acid+urine-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	DM-DS
Prevotella	IL-8	Prevotella-Focal adhesion+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	DM-DS
Prevotella	IL-8	Prevotella-Measles+Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	DM-DS
iso-DCA+blood	IL-8	iso-DCA+blood-IL-1ra+IL-8	Indirect	serum_bileacids	serum_cytokines	0.38	0.579	no	no	no	no	no	no	DM-DS
HCA+stool	IL-8	HCA+stool-HDCA+stool+Eotaxin-IL-8	Indirect	stool_bileacids	serum_cytokines	0.155	0.579	no	no	no	no	no	no	DM-DS
HCA+stool	IL-8	HCA+stool-HDCA+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.155	0.579	no	no	no	no	no	no	DM-DS
Roseburia	IL-8	Roseburia+16:0/18:2-PI+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.495	0.579	no	no	no	no	no	no	DM-DS
Roseburia	IL-8	Roseburia+16:0/18:2-PI+blood-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.495	0.579	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	IL-8	12-ketoDCA+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.505	0.579	no	no	no	no	no	no	DM-DS
GLCA+blood	IL-8	GLCA+blood+TDCA+blood-IL-1ra+IL-8	Indirect	serum_bileacids	serum_cytokines	0.319	0.579	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-8	L-Tryptophan+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-IL-8	Indirect	stool_cometabolism	serum_cytokines	0.557	0.579	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-8	L-Tryptophan+stool+L-Tyrosine+stool-18:2/20:4-PC+blood-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.557	0.579	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-8	L-Tryptophan+stool+8-HETE+blood+Hypotaurine+blood-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.557	0.579	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-8	L-Tryptophan+stool-18:3n6+blood+Hippuric acid+urine-IL-6+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.557	0.579	no	no	no	no	no	no	DM-DS
CA+blood	IL-8	CA+blood+UDCA+blood+Eotaxin-IL-8	Indirect	serum_bileacids	serum_cytokines	0.606	0.579	no	no	no	no	no	no	DM-DS
CA+blood	IL-8	CA+blood+TDCA+blood-IL-1ra+IL-8	Indirect	serum_bileacids	serum_cytokines	0.606	0.579	no	no	no	no	no	no	DM-DS
GUDCA+stool	IL-8	GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-IL-8	Indirect	stool_bileacids	serum_cytokines	0.0085	0.579	no	dn	no	no	no	no	DM-DS
GUDCA+stool	IL-8	GUDCA+stool+12-HEPE+blood-L-Alanine+blood-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0085	0.579	no	dn	no	no	no	no	DM-DS
L-Phenylalanine+stool	IL-8	L-Phenylalanine+stool-UDCA+blood+Eotaxin-IL-8	Indirect	stool_cometabolism	serum_cytokines	0.398	0.579	no	no	no	no	no	no	DM-DS
GCA+stool	IL-8	GCA+stool+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0809	0.579	no	no	no	no	no	no	DM-DS
Coprococcus	IL-8	Coprococcus+Roseburia+16:0/18:2-PI+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	DM-DS
Coprococcus	IL-8	Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	DM-DS
Coprococcus	IL-8	Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	DM-DS
Coprococcus	IL-8	Coprococcus+16:0/16:0-PC+blood+18:0/22:6-PA+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	DM-DS
Coprococcus	IL-8	Coprococcus+16:0/16:0-PC+blood-GDCA+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	DM-DS
Coprococcus	IL-8	Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	DM-DS
Coprococcus	IL-8	Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	DM-DS
Coprococcus	IL-8	Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira-Calcium signaling pathway-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira-Vasopressin-regulated water reabsorption-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira-Melanogenesis-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira-Thyroid hormone synthesis-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira-Endocrine and other factor-regulated calcium reabsorption-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira-Pancreatic secretion-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	"Oscillospira-Parathyroid hormone synthesis, secretion and action-IL-1ra+IL-8"	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira+JAK-STAT signaling pathway-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira-Vibrio cholerae infection+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira+Platinum drug resistance-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira+Progesterone-mediated oocyte maturation-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira-Rap1 signaling pathway+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira+Spliceosome-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira+T cell receptor signaling pathway-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira+MAPK signaling pathway-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira-Platelet activation+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira+FoxO signaling pathway-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira-Focal adhesion+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira+Progesterone-mediated oocyte maturation+Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira-Rap1 signaling pathway-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira+Spliceosome+Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
Oscillospira	IL-8	Oscillospira-Platelet activation-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-DS
HCA+blood	IL-8	HCA+blood+UDCA+blood+Eotaxin-IL-8	Indirect	serum_bileacids	serum_cytokines	0.544	0.579	no	no	no	no	no	no	DM-DS
iso-LCA+stool	IL-8	iso-LCA+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.72	0.579	no	no	no	no	no	no	DM-DS
DCA+blood	IL-8	DCA+blood+nutriCA+blood+UDCA+blood+Eotaxin-IL-8	Indirect	serum_bileacids	serum_cytokines	0.122	0.579	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-8	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-IL-8	Indirect	stool_cometabolism	serum_cytokines	0.33	0.579	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-8	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Alanine+blood-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.33	0.579	no	no	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-8	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-8"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.579	up	up	no	no	no	no	DM-DS
nutriCA+blood	IL-8	nutriCA+blood+UDCA+blood+Eotaxin-IL-8	Indirect	serum_bileacids	serum_cytokines	0.726	0.579	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IL-8	Indole-3-Acetic acid+stool-UDCA+stool+IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.304	0.579	no	no	no	no	no	no	DM-DS
TCA+stool	IL-8	TCA+stool+16:0/18:2-PI+blood-Eotaxin-IL-8	Indirect	stool_bileacids	serum_cytokines	0.458	0.579	no	no	no	no	no	no	DM-DS
TCA+stool	IL-8	TCA+stool+16:0/18:2-PI+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.458	0.579	no	no	no	no	no	no	DM-DS
HDCA+stool	IL-8	HDCA+stool+Eotaxin-IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	DM-DS
HDCA+stool	IL-8	HDCA+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira-p53 signaling pathway+Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Platelet activation-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira-Progesterone-mediated oocyte maturation+Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Rap1 signaling pathway-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira-Spliceosome+Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Leukocyte transendothelial migration-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Oxytocin signaling pathway-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Fluid shear stress and atherosclerosis-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Vibrio cholerae infection+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Carbon metabolism+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Adherens junction+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira-p53 signaling pathway-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Platelet activation+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Bacterial invasion of epithelial cells+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira-Progesterone-mediated oocyte maturation-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira-Platinum drug resistance-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira-T cell receptor signaling pathway-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Regulation of actin cytoskeleton+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Rap1 signaling pathway+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira-Spliceosome-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira-Hippuric acid+urine-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira-Signaling pathways regulating pluripotency of stem cells-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Tight junction+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Leukocyte transendothelial migration+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira-FoxO signaling pathway-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira-ErbB signaling pathway-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Oxytocin signaling pathway+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira-JAK-STAT signaling pathway-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira-Non-small cell lung cancer-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Focal adhesion+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Fluid shear stress and atherosclerosis+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Lachnospira	IL-8	Lachnospira+Carbon metabolism+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-8	Fusobacterium-18:0/18:0-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.628	0.579	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-8	Fusobacterium-18:0/18:1-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.628	0.579	no	no	no	no	no	no	DM-DS
GCDCA+stool	IL-8	GCDCA+stool+UDCA+stool+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool-UDCA+stool+IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter+Pathogenic Escherichia coli infection+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter+Antigen processing and presentation+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter+Leishmaniasis+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter-Chemical carcinogenesis - receptor activation-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter+Carbon metabolism+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter-HDCA+stool+Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter+Neuroactive ligand-receptor interaction-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter+16:0/20:4-PI+blood-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter-Thyroid hormone synthesis-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter+Salmonella infection+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter-12-ketoDCA+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter-Cocaine addiction-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter-iso-LCA+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter-Regulation of lipolysis in adipocytes-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter+GCA+stool+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter-Insulin secretion-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter-GnRH signaling pathway-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter-Cushing syndrome-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter-HDCA+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter-Cortisol synthesis and secretion-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	"Odoribacter-Growth hormone synthesis, secretion and action-IL-1ra+IL-8"	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter-Gap junction-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter+16:0/20:4-PI+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter-Endocrine resistance-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter-Chemical carcinogenesis - receptor activation-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter-LCA+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter-Long-term depression-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter+Carbon metabolism+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Odoribacter	IL-8	Odoribacter+Longevity regulating pathway - multiple species+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-DS
Actinomyces	IL-8	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.621	0.579	no	no	no	no	no	no	DM-DS
Actinomyces	IL-8	Actinomyces+Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.621	0.579	no	no	no	no	no	no	DM-DS
Actinomyces	IL-8	Actinomyces+Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.621	0.579	no	no	no	no	no	no	DM-DS
Actinomyces	IL-8	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:0/22:6-PA+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.621	0.579	no	no	no	no	no	no	DM-DS
Actinomyces	IL-8	Actinomyces+Coprococcus+16:0/16:0-PC+blood-GDCA+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.621	0.579	no	no	no	no	no	no	DM-DS
Actinomyces	IL-8	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.621	0.579	no	no	no	no	no	no	DM-DS
Actinomyces	IL-8	Actinomyces+Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.621	0.579	no	no	no	no	no	no	DM-DS
Actinomyces	IL-8	Actinomyces+Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.621	0.579	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IL-8	Isobutyric acid+stool-UDCA+stool+IL-1ra+IL-8	Indirect	stool_scfa	serum_cytokines	0.408	0.579	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	IL-8	"2-hydroxyphenylacetic acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-8"	Indirect	urine_cometabolism	serum_cytokines	0.763	0.579	no	no	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-8	Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-IL-8	Indirect	stool_cometabolism	serum_cytokines	0.037	0.579	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-8	Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-IL-8	Indirect	stool_cometabolism	serum_cytokines	0.037	0.579	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-8	Kynurenic acid+stool-nutriCA+stool+18:0/18:0-PC+blood+IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.037	0.579	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-8	Kynurenic acid+stool-nutriCA+stool+18:0/22:6-PA+blood+IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.037	0.579	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-8	Kynurenic acid+stool-nutriCA+stool+UDCA+stool+IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.037	0.579	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-8	Kynurenic acid+stool+L-Tyrosine+stool-18:2/20:4-PC+blood-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.037	0.579	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-8	Kynurenic acid+stool-nutriCA+stool+18:0/18:1-PC+blood+IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.037	0.579	dn	dn	no	no	no	no	DM-DS
Caproic acid+stool	IL-8	Caproic acid+stool-GCA+stool+IL-1ra+IL-8	Indirect	stool_scfa	serum_cytokines	0.882	0.579	no	no	no	no	no	no	DM-DS
Eggerthella	IL-8	Eggerthella+Phosphatidylinositol signaling system-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.912	0.579	no	no	no	no	no	no	DM-DS
Eggerthella	IL-8	Eggerthella-iso-LCA+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.912	0.579	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-8	Anaerotruncus-Ruminococcus+18:0/18:0-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.904	0.579	no	no	no	no	no	no	DM-DS
Anaerostipes	IL-8	Anaerostipes+Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	DM-DS
Anaerostipes	IL-8	Anaerostipes-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-8	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-IL-8	Indirect	stool_bileacids	serum_cytokines	0.241	0.579	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-8	TUDCA+stool+9-HODE+blood+AA+blood+L-2-Aminobutyric acid+blood+Eotaxin-IL-8	Indirect	stool_bileacids	serum_cytokines	0.241	0.579	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-8	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-L-2-Aminobutyric acid+blood+Eotaxin-IL-8	Indirect	stool_bileacids	serum_cytokines	0.241	0.579	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-8	TUDCA+stool-14:0/18:2-PC+blood+24:0+blood-P-hydroxyhippuric acid+urine+Eotaxin-IL-8	Indirect	stool_bileacids	serum_cytokines	0.241	0.579	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-8	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+L-Citrulline+blood+Eotaxin-IL-8	Indirect	stool_bileacids	serum_cytokines	0.241	0.579	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-8	TUDCA+stool-d18:1-14:0-SM+blood-L-Asparagine+blood+L-Citrulline+blood+Eotaxin-IL-8	Indirect	stool_bileacids	serum_cytokines	0.241	0.579	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-8	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood-UDCA+blood+Eotaxin-IL-8	Indirect	stool_bileacids	serum_cytokines	0.241	0.579	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-8	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-UDCA+blood+Eotaxin-IL-8	Indirect	stool_bileacids	serum_cytokines	0.241	0.579	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-8	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood+TDCA+blood-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.241	0.579	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-8	TUDCA+stool-14:0/18:2-PC+blood-Creatinine+blood+iso-DCA+blood-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.241	0.579	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-8	TUDCA+stool-14:0/18:2-PC+blood+24:0+blood-P-hydroxyhippuric acid+urine-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.241	0.579	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-8	TUDCA+stool-14:0/18:2-PC+blood+14:0/20:4-PC+blood+18:2/20:4-PC+blood-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.241	0.579	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-8	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+Hypotaurine+blood-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.241	0.579	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-8	TUDCA+stool-d18:1-14:0-SM+blood-Ethanolamine+blood+Hypotaurine+blood-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.241	0.579	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-8	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:3/16:0-PC+blood-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.241	0.579	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IL-8	Isovaleric acid+stool-UDCA+stool+IL-1ra+IL-8	Indirect	stool_scfa	serum_cytokines	0.343	0.579	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-8	Paraprevotella-IL-17 signaling pathway+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.118	0.579	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-8	Paraprevotella+Ribosome biogenesis in eukaryotes-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.118	0.579	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-8	Paraprevotella+Cell cycle-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.118	0.579	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-8	Paraprevotella-IL-17 signaling pathway-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.118	0.579	no	no	no	no	no	no	DM-DS
TDCA+blood	IL-8	TDCA+blood-IL-1ra+IL-8	Indirect	serum_bileacids	serum_cytokines	0.155	0.579	no	up	no	no	no	no	DM-DS
¦Ø-MCA+stool	IL-8	¦Ø-MCA+stool+CDCA+stool+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.919	0.579	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-8	Phenylacetic acid+stool-UDCA+blood+Eotaxin-IL-8	Indirect	stool_cometabolism	serum_cytokines	0.785	0.579	no	no	no	no	no	no	DM-DS
Gemmiger	IL-8	Gemmiger+Signaling pathways regulating pluripotency of stem cells-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	DM-DS
Gemmiger	IL-8	Gemmiger+Pathways in cancer-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	DM-DS
Gemmiger	IL-8	Gemmiger+ErbB signaling pathway-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	DM-DS
Gemmiger	IL-8	Gemmiger+Gastric cancer-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	DM-DS
GDCA+stool	IL-8	GDCA+stool+UDCA+stool+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.656	0.579	no	no	no	no	no	no	DM-DS
Methanobrevibacter	IL-8	Methanobrevibacter-Cystine+blood+L-Alanine+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.629	0.579	no	no	no	no	no	no	DM-DS
Methanobrevibacter	IL-8	Methanobrevibacter-Alcoholism-Gastric cancer-IL-6+IL-8	Indirect	Genus	serum_cytokines	0.629	0.579	no	no	no	no	no	no	DM-DS
Methanobrevibacter	IL-8	Methanobrevibacter-Alcoholism+Systemic lupus erythematosus+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.629	0.579	no	no	no	no	no	no	DM-DS
Methanobrevibacter	IL-8	Methanobrevibacter-Alcoholism-Measles+Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.629	0.579	no	no	no	no	no	no	DM-DS
Methanobrevibacter	IL-8	Methanobrevibacter-Alcoholism+Systemic lupus erythematosus-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.629	0.579	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IL-8	L-Tyrosine+stool-UDCA+blood+Eotaxin-IL-8	Indirect	stool_cometabolism	serum_cytokines	0.44	0.579	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IL-8	L-Tyrosine+stool-18:2/20:4-PC+blood-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.44	0.579	no	no	no	no	no	no	DM-DS
CDCA+stool	IL-8	CDCA+stool+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.663	0.579	no	no	no	no	no	no	DM-DS
CA+stool	IL-8	CA+stool-LCA+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.827	0.579	no	no	no	no	no	no	DM-DS
CA+stool	IL-8	CA+stool+GCA+stool+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.827	0.579	no	no	no	no	no	no	DM-DS
CA+stool	IL-8	CA+stool+CDCA+stool+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.827	0.579	no	no	no	no	no	no	DM-DS
CA+stool	IL-8	CA+stool-iso-LCA+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.827	0.579	no	no	no	no	no	no	DM-DS
CA+stool	IL-8	CA+stool+UDCA+stool+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.827	0.579	no	no	no	no	no	no	DM-DS
HDCA+blood	IL-8	HDCA+blood+Hypotaurine+blood-IL-1ra+IL-8	Indirect	serum_bileacids	serum_cytokines	0.483	0.579	no	no	no	no	no	no	DM-DS
UDCA+stool	IL-8	UDCA+stool+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.266	0.579	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-8	TDCA+stool-12-ketoDCA+blood+GDCA+blood-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.963	0.579	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-8	TDCA+stool-HDCA+blood+Hypotaurine+blood-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.963	0.579	no	no	no	no	no	no	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	IL-8	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2+IL-8	Indirect	urine_cometabolism	serum_cytokines	0.973	0.579	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-8	Desulfovibrio+Antigen processing and presentation+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.27	0.579	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-8	nutriCA+stool+18:0/22:6-PA+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.481	0.579	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-8	nutriCA+stool+UDCA+stool+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.481	0.579	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-8	nutriCA+stool+18:0/18:1-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.481	0.579	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-8	nutriCA+stool+18:0/18:0-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.481	0.579	no	no	no	no	no	no	DM-DS
Bilophila	IL-8	Bilophila+Desulfovibrio+Antigen processing and presentation+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.528	0.579	no	no	no	no	no	no	DM-DS
GDCA+blood	IL-8	GDCA+blood-IL-1ra+IL-8	Indirect	serum_bileacids	serum_cytokines	0.632	0.579	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	IL-8	P-hydroxyhippuric acid+urine-IL-1ra+IL-8	Indirect	urine_cometabolism	serum_cytokines	0.436	0.579	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	IL-8	P-hydroxyhippuric acid+urine+Eotaxin-IL-8	Indirect	urine_cometabolism	serum_cytokines	0.436	0.579	no	no	no	no	no	no	DM-DS
acetic acid C2+blood	IL-8	acetic acid C2+blood+d18:1-22:1-SM+blood+HDCA+blood+Hypotaurine+blood-IL-1ra+IL-8	Indirect	serum_scfa	serum_cytokines	0.000193	0.579	up	dn	no	no	no	no	DM-DS
acetic acid C2+blood	IL-8	acetic acid C2+blood+d18:1-20:1-SM+blood+HDCA+blood+Hypotaurine+blood-IL-1ra+IL-8	Indirect	serum_scfa	serum_cytokines	0.000193	0.579	up	dn	no	no	no	no	DM-DS
acetic acid C2+blood	IL-8	acetic acid C2+blood+d18:1-20:1-SM+blood-GUDCA+blood+UDCA+blood+Eotaxin-IL-8	Indirect	serum_scfa	serum_cytokines	0.000193	0.579	up	dn	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	IL-8	isovaleric acid iso-C5+blood+PUFA+blood+SFA+blood-P-hydroxyhippuric acid+urine-IL-1ra+IL-8	Indirect	serum_scfa	serum_cytokines	0.117	0.579	no	no	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	IL-8	isovaleric acid iso-C5+blood+PUFA+blood+SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin-IL-8	Indirect	serum_scfa	serum_cytokines	0.117	0.579	no	no	no	no	no	no	DM-DS
Clostridium	IL-8	Clostridium-Eotaxin-IL-8	Indirect	Genus	serum_cytokines	0.925	0.579	no	no	no	no	no	no	DM-DS
Clostridium	IL-8	Clostridium+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.925	0.579	no	no	no	no	no	no	DM-DS
Clostridium	IL-8	Clostridium+IL-6+IL-8	Indirect	Genus	serum_cytokines	0.925	0.579	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	IL-8	T-¦Á-MCA+stool-UDCA+stool+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.48	0.579	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-8	12-ketoDCA+blood+GDCA+blood-IL-1ra+IL-8	Indirect	serum_bileacids	serum_cytokines	0.517	0.579	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-8	Butyricicoccus-18:2/20:4-PC+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.852	0.579	no	no	no	no	no	no	DM-DS
Blautia	Resistin	Blautia+Creatinine+blood+Resistin	Indirect	Genus	DM-associated hormones	1.36E-05	0.156	up	dn	dn	no	no	no	DM-DS
Parabacteroides	Resistin	Parabacteroides-16:0/18:2-PI+blood-20:1+blood+Resistin	Indirect	Genus	DM-associated hormones	4.19E-05	0.156	no	up	up	no	no	no	DM-DS
Parabacteroides	Resistin	Parabacteroides-L-Phenylalanine+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	4.19E-05	0.156	no	up	up	no	no	no	DM-DS
Parabacteroides	Resistin	Parabacteroides+d18:1-14:0-SM+blood-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	4.19E-05	0.156	no	up	up	no	no	no	DM-DS
Parabacteroides	Resistin	Parabacteroides+20:0+blood-Creatinine+blood+Resistin	Indirect	Genus	DM-associated hormones	4.19E-05	0.156	no	up	up	no	no	no	DM-DS
Parabacteroides	Resistin	Parabacteroides+16:0/20:5-PC+blood-Creatinine+blood+Resistin	Indirect	Genus	DM-associated hormones	4.19E-05	0.156	no	up	up	no	no	no	DM-DS
Dorea	Resistin	Dorea-20:1+blood+Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	DM-DS
Faecalibacterium	Resistin	Faecalibacterium-d18:1-16:1-SM+blood-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0039	0.156	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	Resistin	Faecalibacterium-d18:1-14:0-SM+blood-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0039	0.156	no	dn	dn	no	no	no	DM-DS
Bacteroides	Resistin	Bacteroides-Transcriptional misregulation in cancer+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	DM-DS
Bacteroides	Resistin	Bacteroides+RNA transport-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	DM-DS
Bacteroides	Resistin	Bacteroides+Apelin signaling pathway-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	DM-DS
Bacteroides	Resistin	Bacteroides-Amoebiasis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	DM-DS
Bacteroides	Resistin	Bacteroides-20:1-LPA+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	DM-DS
Bacteroides	Resistin	Bacteroides+Long-term potentiation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	DM-DS
Bacteroides	Resistin	Bacteroides-20:1-LPA+blood+Creatinine+blood+Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	DM-DS
Bacteroides	Resistin	Bacteroides+16:0/20:5-PC+blood-Creatinine+blood+Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	DM-DS
Bacteroides	Resistin	Bacteroides+20:5n3+blood-Creatinine+blood+Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	DM-DS
Bacteroides	Resistin	Bacteroides+Oocyte meiosis-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	DM-DS
Bacteroides	Resistin	Bacteroides-Relaxin signaling pathway+13-HODE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	DM-DS
Propionic acid+stool	Resistin	Propionic acid+stool+18:0-LPE+blood-8-HETE+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.156	dn	no	up	no	no	no	DM-DS
[Ruminococcus]	Resistin	[Ruminococcus]-20:1+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0679	0.156	no	no	dn	no	no	no	DM-DS
GUDCA+blood	Resistin	GUDCA+blood+HCA+blood-UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.156	no	no	dn	no	no	no	DM-DS
Acetic acid+stool	Resistin	Acetic acid+stool+20:1+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.156	dn	no	no	no	no	no	DM-DS
Alistipes	Resistin	Alistipes+Platinum drug resistance-Viral protein interaction with cytokine and cytokine receptor+Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-DS
Alistipes	Resistin	Alistipes+20:0+blood-Creatinine+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-DS
Alistipes	Resistin	Alistipes+d18:1-16:1-SM+blood-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-DS
Alistipes	Resistin	Alistipes-L-Glutamic acid+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-DS
Alistipes	Resistin	Alistipes-18:1/16:0-PC+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-DS
Alistipes	Resistin	Alistipes+Colorectal cancer-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-DS
Alistipes	Resistin	Alistipes-L-Phenylalanine+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-DS
Alistipes	Resistin	Alistipes-Serine+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-DS
Alistipes	Resistin	Alistipes-18:2/16:0-PC+blood+8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-DS
Alistipes	Resistin	Alistipes-18:1/16:0-PC+blood+8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-DS
Alistipes	Resistin	Alistipes+18:0-LPC+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-DS
Alistipes	Resistin	Alistipes-18:1/16:0-PC+blood-18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-DS
Alistipes	Resistin	Alistipes+Colorectal cancer+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-DS
Alistipes	Resistin	Alistipes+18:0-LPC+blood+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-DS
Alistipes	Resistin	Alistipes+nutriCA+stool-13-HODE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-DS
Butyricimonas	Resistin	Butyricimonas-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	DM-DS
Butyricimonas	Resistin	Butyricimonas-Creatinine+blood+Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	DM-DS
Collinsella	Resistin	Collinsella-Inflammatory mediator regulation of TRP channels-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.128	0.156	no	no	no	no	no	no	DM-DS
Collinsella	Resistin	Collinsella-d18:1-16:1-SM+blood-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.128	0.156	no	no	no	no	no	no	DM-DS
Collinsella	Resistin	Collinsella-GnRH signaling pathway+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.128	0.156	no	no	no	no	no	no	DM-DS
Collinsella	Resistin	Collinsella-Inflammatory mediator regulation of TRP channels+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.128	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina+Prostate cancer+8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina+TNF signaling pathway+8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina+Viral carcinogenesis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina-Glucagon signaling pathway-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina+Osteoclast differentiation+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina-Inflammatory mediator regulation of TRP channels-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina-Dopaminergic synapse-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina+Cellular senescence+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina+Human papillomavirus infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina+Apoptosis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina+NF-kappa B signaling pathway+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina-Amphetamine addiction-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina+Toll-like receptor signaling pathway+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina+RIG-I-like receptor signaling pathway+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina-Aldosterone synthesis and secretion-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina+Fc epsilon RI signaling pathway+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina+C-type lectin receptor signaling pathway+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina-Glucagon signaling pathway+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina-Inflammatory mediator regulation of TRP channels+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina-Amphetamine addiction+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina-GnRH signaling pathway+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Sarcina	Resistin	Sarcina-Aldosterone synthesis and secretion+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Methanosphaera	Resistin	Methanosphaera-Roseburia+16:0/16:1-PC+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Methanosphaera	Resistin	Methanosphaera-Roseburia+20:3n6+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Methanosphaera	Resistin	Methanosphaera-Roseburia+16:0/18:2-PI+blood-20:1+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
Methanosphaera	Resistin	Methanosphaera-Roseburia+L-Phenylalanine+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0703	0.156	no	no	no	no	no	no	DM-DS
iso-DCA+stool	Resistin	iso-DCA+stool+Propionic acid+stool+18:0-LPE+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-TDCA+stool-d18:1-16:0-SM+blood+d18:1-16:1-SM+blood-UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+L-Lysine+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-TDCA+stool-12-ketoDCA+blood+Ethanolamine+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-UDCA+stool-GDCA+blood+PUFA/MUFA+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:1/16:0-PC+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-UDCA+stool+18:0/20:3-PI+blood+20:2/18:1-PE+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+20:3n6+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-UDCA+stool+18:0/20:3-PI+blood+20:3n6+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+20:2/18:0-PC+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-UDCA+stool+18:0/20:3-PI+blood+20:2/18:0-PC+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:1/16:0-PC+blood+8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:0/20:3-PC+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PG+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PG+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:0/16:0-PC+blood-18:3n6+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:1/16:0-PC+blood-18:3n6+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
LCA+stool	Resistin	LCA+stool-TDCA+stool-12-ketoDCA+blood-18:1+blood+20:1+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-DS
Akkermansia	Resistin	Akkermansia+Proteoglycans in cancer-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.23	0.156	no	no	no	no	no	no	DM-DS
Akkermansia	Resistin	Akkermansia-Cytokine-cytokine receptor interaction+Viral protein interaction with cytokine and cytokine receptor+Resistin	Indirect	Genus	DM-associated hormones	0.23	0.156	no	no	no	no	no	no	DM-DS
Bifidobacterium	Resistin	Bifidobacterium+HIF-1 signaling pathway-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.105	0.156	no	dn	no	no	no	no	DM-DS
Bifidobacterium	Resistin	Bifidobacterium+Proteoglycans in cancer-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.105	0.156	no	dn	no	no	no	no	DM-DS
Bifidobacterium	Resistin	Bifidobacterium-Transcriptional misregulation in cancer+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.105	0.156	no	dn	no	no	no	no	DM-DS
Bifidobacterium	Resistin	Bifidobacterium-Hepatitis B+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.105	0.156	no	dn	no	no	no	no	DM-DS
Bifidobacterium	Resistin	Bifidobacterium+L-Phenylalanine+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.105	0.156	no	dn	no	no	no	no	DM-DS
Bifidobacterium	Resistin	Bifidobacterium-18:1+blood+20:1+blood+Resistin	Indirect	Genus	DM-associated hormones	0.105	0.156	no	dn	no	no	no	no	DM-DS
Ruminococcus	Resistin	Ruminococcus+nutriCA+stool-13-HODE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.335	0.156	no	no	no	no	no	no	DM-DS
Ruminococcus	Resistin	Ruminococcus+20:2/18:0-PC+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.335	0.156	no	no	no	no	no	no	DM-DS
Ruminococcus	Resistin	Ruminococcus-18:2/16:0-PC+blood+8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.335	0.156	no	no	no	no	no	no	DM-DS
Ruminococcus	Resistin	Ruminococcus+18:0/20:3-PC+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.335	0.156	no	no	no	no	no	no	DM-DS
GCDCA+blood	Resistin	GCDCA+blood+HCA+blood-UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.156	no	no	no	no	no	no	DM-DS
ACA+blood	Resistin	ACA+blood-decanoic acid C10+blood+L-Phenylalanine+blood+UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.156	no	no	no	no	no	no	DM-DS
DCA+stool	Resistin	DCA+stool-L-Tryptophan+stool+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.156	no	no	no	no	no	no	DM-DS
Butyric acid+stool	Resistin	Butyric acid+stool-16:0/20:5-PC+blood-Creatinine+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.102	0.156	dn	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	Resistin	4-hydroxybenzoic acid+stool+L-Tryptophan+stool+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.156	no	dn	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+Viral myocarditis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Viral myocarditis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+Viral myocarditis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Viral myocarditis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+Viral myocarditis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-d18:1-16:1-SM+blood-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Pathogenic Escherichia coli infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Natural killer cell mediated cytotoxicity+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Staphylococcus aureus infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Pertussis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Salmonella infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Type I diabetes mellitus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Tuberculosis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+Autoimmune thyroid disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Autoimmune thyroid disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+Autoimmune thyroid disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Autoimmune thyroid disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+Autoimmune thyroid disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+Allograft rejection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Allograft rejection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+Allograft rejection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Allograft rejection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+Allograft rejection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Human papillomavirus infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation-Colorectal cancer-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Viral carcinogenesis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+Viral carcinogenesis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Rheumatoid arthritis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+Rheumatoid arthritis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Rheumatoid arthritis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-Chemical carcinogenesis - receptor activation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-Chemical carcinogenesis - receptor activation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-Chemical carcinogenesis - receptor activation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation-Chemical carcinogenesis - receptor activation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-Chemical carcinogenesis - receptor activation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+Graft-versus-host disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Graft-versus-host disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+Graft-versus-host disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Graft-versus-host disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+Graft-versus-host disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation-Cushing syndrome-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Pathogenic Escherichia coli infection-18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Salmonella infection-18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation-Colorectal cancer+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation-GnRH signaling pathway+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation+Pathogenic Escherichia coli infection+8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-DCA+stool-L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-DCA+stool-L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-DCA+stool-L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Antigen processing and presentation-DCA+stool-L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-DCA+stool-L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+Renal cell carcinoma+L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Renal cell carcinoma+L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+Renal cell carcinoma+L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
Turicibacter	Resistin	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+Renal cell carcinoma+L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.269	0.156	no	no	no	no	no	no	DM-DS
GCA+blood	Resistin	GCA+blood+HCA+blood-UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.156	no	no	no	no	no	no	DM-DS
GCA+blood	Resistin	GCA+blood-Serine+blood+UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.156	no	no	no	no	no	no	DM-DS
ACA+stool	Resistin	ACA+stool-L-Tryptophan+stool+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.156	no	no	no	no	no	no	DM-DS
CDCA+blood	Resistin	CDCA+blood-UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.156	no	no	no	no	no	no	DM-DS
capric acid C6+blood	Resistin	capric acid C6+blood-HCA+blood-UFA%+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.433	0.156	no	no	no	no	no	no	DM-DS
Prevotella	Resistin	Prevotella+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-DS
iso-DCA+blood	Resistin	iso-DCA+blood+L-Asparagine+blood+UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.156	no	no	no	no	no	no	DM-DS
HCA+stool	Resistin	HCA+stool-HDCA+stool-Cysteine+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.156	no	no	no	no	no	no	DM-DS
HCA+stool	Resistin	HCA+stool-HDCA+stool-16:0/20:4-PI+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.156	no	no	no	no	no	no	DM-DS
Roseburia	Resistin	Roseburia+16:0/16:1-PC+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.495	0.156	no	no	no	no	no	no	DM-DS
Roseburia	Resistin	Roseburia+20:3n6+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.495	0.156	no	no	no	no	no	no	DM-DS
Roseburia	Resistin	Roseburia+16:0/18:2-PI+blood-20:1+blood+Resistin	Indirect	Genus	DM-associated hormones	0.495	0.156	no	no	no	no	no	no	DM-DS
Roseburia	Resistin	Roseburia+L-Phenylalanine+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.495	0.156	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	Resistin	12-ketoDCA+stool-MUFA%+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.156	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	Resistin	12-ketoDCA+stool+DCA+stool-L-Tryptophan+stool+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.156	no	no	no	no	no	no	DM-DS
GLCA+blood	Resistin	GLCA+blood-MUFA+blood+MUFA%+blood+UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.156	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	Resistin	L-Tryptophan+stool+Resistin	Direct	stool_cometabolism	DM-associated hormones	0.557	0.156	no	no	no	no	no	no	DM-DS
CA+blood	Resistin	CA+blood-UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.156	no	no	no	no	no	no	DM-DS
GUDCA+stool	Resistin	GUDCA+stool+TUDCA+stool-d18:1-14:0-SM+blood-UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.156	no	dn	no	no	no	no	DM-DS
GUDCA+stool	Resistin	GUDCA+stool+12-HEPE+blood+18:1/18:0-PI+blood-UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.156	no	dn	no	no	no	no	DM-DS
GUDCA+stool	Resistin	GUDCA+stool+12-HEPE+blood-Cystine+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.156	no	dn	no	no	no	no	DM-DS
GUDCA+stool	Resistin	GUDCA+stool+12-HEPE+blood-L-Phenylalanine+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.156	no	dn	no	no	no	no	DM-DS
GUDCA+stool	Resistin	GUDCA+stool+12-HEPE+blood-L-Methionine+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.156	no	dn	no	no	no	no	DM-DS
GUDCA+stool	Resistin	GUDCA+stool+TUDCA+stool-14:0/18:2-PC+blood-Creatinine+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.156	no	dn	no	no	no	no	DM-DS
GUDCA+stool	Resistin	GUDCA+stool+12-HEPE+blood+16:0/20:5-PC+blood-Creatinine+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.156	no	dn	no	no	no	no	DM-DS
L-Phenylalanine+stool	Resistin	L-Phenylalanine+stool+8-HETE+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.156	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	Resistin	L-Phenylalanine+stool+L-Tryptophan+stool+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.156	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	Resistin	L-Phenylalanine+stool-18:3n6+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.156	no	no	no	no	no	no	DM-DS
butyric acid C4+blood	Resistin	butyric acid C4+blood+L-Ornithine+blood+Taurine+blood+UFA%+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.407	0.156	no	no	no	no	no	no	DM-DS
GCA+stool	Resistin	GCA+stool+DPA+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.156	no	no	no	no	no	no	DM-DS
Coprococcus	Resistin	Coprococcus-14:0/18:2-PC+blood-Creatinine+blood+Resistin	Indirect	Genus	DM-associated hormones	0.612	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	Oscillospira-Inflammatory mediator regulation of TRP channels+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	Oscillospira+Platinum drug resistance-Viral protein interaction with cytokine and cytokine receptor+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	Oscillospira+Spliceosome-Viral protein interaction with cytokine and cytokine receptor+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	Oscillospira-Thermogenesis-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	Oscillospira-Ribosome-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	Oscillospira-Prion disease-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	Oscillospira-Huntington disease-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	Oscillospira-Alzheimer disease-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	Oscillospira-Dopaminergic synapse-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	Oscillospira-Coronavirus disease - COVID-19-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	Oscillospira-Retrograde endocannabinoid signaling-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	Oscillospira+Hepatitis B+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	Oscillospira-Inflammatory mediator regulation of TRP channels-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	Oscillospira-Diabetic cardiomyopathy-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	Oscillospira-Oxidative phosphorylation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	Oscillospira+NF-kappa B signaling pathway+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	Oscillospira-Cardiac muscle contraction-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
Oscillospira	Resistin	"Oscillospira-Parathyroid hormone synthesis, secretion and action-UFA%+blood+Resistin"	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-DS
HCA+blood	Resistin	HCA+blood-UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.544	0.156	no	no	no	no	no	no	DM-DS
iso-LCA+stool	Resistin	iso-LCA+stool-TCA+stool+16:0/18:2-PI+blood-20:1+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.156	no	no	no	no	no	no	DM-DS
DCA+blood	Resistin	DCA+blood+L-Histidine+blood+PUFA/UFA+blood+UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.156	no	no	no	no	no	no	DM-DS
DCA+blood	Resistin	DCA+blood+L-Histidine+blood+Taurine+blood+UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.156	no	no	no	no	no	no	DM-DS
DCA+blood	Resistin	DCA+blood+L-Histidine+blood+L-Lysine+blood+UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.156	no	no	no	no	no	no	DM-DS
DCA+blood	Resistin	DCA+blood+L-Histidine+blood+PUFA%+blood+UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.156	no	no	no	no	no	no	DM-DS
DCA+blood	Resistin	DCA+blood+L-Histidine+blood+L-Methionine+blood+UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.156	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	Resistin	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-d18:1-14:0-SM+blood-UFA%+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.156	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	Resistin	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-14:0/18:2-PC+blood-Creatinine+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.156	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	Resistin	Indole-3-Acetic acid+stool-nutriCA+stool-13-HODE+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.156	no	no	no	no	no	no	DM-DS
TCA+stool	Resistin	TCA+stool+16:0/18:2-PI+blood-20:1+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	DM-DS
HDCA+stool	Resistin	HDCA+stool-Cysteine+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.156	no	no	no	no	no	no	DM-DS
HDCA+stool	Resistin	HDCA+stool-16:0/20:4-PI+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.156	no	no	no	no	no	no	DM-DS
Lachnospira	Resistin	Lachnospira-Prostate cancer+8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-DS
Lachnospira	Resistin	Lachnospira-TNF signaling pathway+8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-DS
Lachnospira	Resistin	Lachnospira-Platinum drug resistance-Viral protein interaction with cytokine and cytokine receptor+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-DS
Lachnospira	Resistin	Lachnospira-Spliceosome-Viral protein interaction with cytokine and cytokine receptor+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-DS
Lachnospira	Resistin	Lachnospira-Hepatitis B+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-DS
Lachnospira	Resistin	Lachnospira-RIG-I-like receptor signaling pathway+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-DS
Lachnospira	Resistin	Lachnospira-Transcriptional misregulation in cancer+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-DS
Lachnospira	Resistin	Lachnospira+L-Methionine+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-DS
Lachnospira	Resistin	Lachnospira-NOD-like receptor signaling pathway+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-DS
Lachnospira	Resistin	Lachnospira-NF-kappa B signaling pathway+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-DS
Fusobacterium	Resistin	Fusobacterium-18:1/16:0-PC+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.628	0.156	no	no	no	no	no	no	DM-DS
Fusobacterium	Resistin	Fusobacterium-16:0/18:2-PC+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.628	0.156	no	no	no	no	no	no	DM-DS
Fusobacterium	Resistin	Fusobacterium+18:0-LPE+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.628	0.156	no	no	no	no	no	no	DM-DS
Fusobacterium	Resistin	Fusobacterium-18:1/16:0-PC+blood+8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.628	0.156	no	no	no	no	no	no	DM-DS
Fusobacterium	Resistin	Fusobacterium-18:1/16:0-PC+blood-18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.628	0.156	no	no	no	no	no	no	DM-DS
Fusobacterium	Resistin	Fusobacterium-16:0/18:2-PC+blood-18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.628	0.156	no	no	no	no	no	no	DM-DS
Fusobacterium	Resistin	Fusobacterium-18:0/16:0-PC+blood-18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.628	0.156	no	no	no	no	no	no	DM-DS
GCDCA+stool	Resistin	GCDCA+stool+20:3n6+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.156	no	dn	no	no	no	no	DM-DS
GCDCA+stool	Resistin	GCDCA+stool+16:0/16:1-PC+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.156	no	dn	no	no	no	no	DM-DS
GCDCA+stool	Resistin	GCDCA+stool+18:1/16:0-PC+blood+8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.156	no	dn	no	no	no	no	DM-DS
GCDCA+stool	Resistin	GCDCA+stool-L-Phenylalanine+stool+8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.156	no	dn	no	no	no	no	DM-DS
GCDCA+stool	Resistin	GCDCA+stool+18:1/16:0-PC+blood-18:3n6+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.156	no	dn	no	no	no	no	DM-DS
GCDCA+stool	Resistin	GCDCA+stool+16:0/18:2-PC+blood-18:3n6+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.156	no	dn	no	no	no	no	DM-DS
GCDCA+stool	Resistin	GCDCA+stool-L-Phenylalanine+stool-18:3n6+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.156	no	dn	no	no	no	no	DM-DS
GCDCA+stool	Resistin	GCDCA+stool-L-Phenylalanine+stool+L-Tryptophan+stool+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.156	no	dn	no	no	no	no	DM-DS
GCDCA+stool	Resistin	GCDCA+stool+18:1/16:0-PC+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.156	no	dn	no	no	no	no	DM-DS
GCDCA+stool	Resistin	GCDCA+stool+16:0/18:2-PC+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.156	no	dn	no	no	no	no	DM-DS
GCDCA+stool	Resistin	GCDCA+stool+L-Phenylalanine+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.156	no	dn	no	no	no	no	DM-DS
GCDCA+stool	Resistin	GCDCA+stool+Cystine+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.156	no	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	Resistin	5-Hydroxytryptamine+stool-nutriCA+stool-13-HODE+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.156	dn	dn	no	no	no	no	DM-DS
Odoribacter	Resistin	Odoribacter+Pathogenic Escherichia coli infection+8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.798	0.156	no	no	no	no	no	no	DM-DS
Odoribacter	Resistin	Odoribacter+16:0/20:4-PI+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.798	0.156	no	no	no	no	no	no	DM-DS
Odoribacter	Resistin	Odoribacter+Salmonella infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.798	0.156	no	no	no	no	no	no	DM-DS
Odoribacter	Resistin	Odoribacter+Pathogenic Escherichia coli infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.798	0.156	no	no	no	no	no	no	DM-DS
Odoribacter	Resistin	Odoribacter-Cushing syndrome-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.798	0.156	no	no	no	no	no	no	DM-DS
Odoribacter	Resistin	Odoribacter+Neuroactive ligand-receptor interaction+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.798	0.156	no	no	no	no	no	no	DM-DS
Odoribacter	Resistin	Odoribacter-Chemical carcinogenesis - receptor activation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.798	0.156	no	no	no	no	no	no	DM-DS
Odoribacter	Resistin	Odoribacter+Fc gamma R-mediated phagocytosis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.798	0.156	no	no	no	no	no	no	DM-DS
Odoribacter	Resistin	Odoribacter-DCA+stool-L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.798	0.156	no	no	no	no	no	no	DM-DS
Odoribacter	Resistin	Odoribacter-Gap junction+13-HODE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.798	0.156	no	no	no	no	no	no	DM-DS
Odoribacter	Resistin	Odoribacter+Salmonella infection-18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.798	0.156	no	no	no	no	no	no	DM-DS
Odoribacter	Resistin	Odoribacter+Pathogenic Escherichia coli infection-18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.798	0.156	no	no	no	no	no	no	DM-DS
Odoribacter	Resistin	Odoribacter-GnRH signaling pathway+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.798	0.156	no	no	no	no	no	no	DM-DS
Odoribacter	Resistin	Odoribacter-Endocrine resistance+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.798	0.156	no	no	no	no	no	no	DM-DS
Actinomyces	Resistin	Actinomyces+Coprococcus-14:0/18:2-PC+blood-Creatinine+blood+Resistin	Indirect	Genus	DM-associated hormones	0.621	0.156	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	Resistin	Isobutyric acid+stool-nutriCA+stool-13-HODE+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.408	0.156	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	Resistin	Isobutyric acid+stool+L-Phenylalanine+stool+8-HETE+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.408	0.156	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	Resistin	Isobutyric acid+stool+L-Phenylalanine+stool+L-Tryptophan+stool+Resistin	Indirect	stool_scfa	DM-associated hormones	0.408	0.156	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	Resistin	Isobutyric acid+stool+L-Phenylalanine+stool-18:3n6+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.408	0.156	no	no	no	no	no	no	DM-DS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool+L-Phenylalanine+stool+L-Tryptophan+stool+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool+L-Phenylalanine+stool+8-HETE+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool-nutriCA+stool-13-HODE+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool+L-Phenylalanine+stool-18:3n6+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-DS
Caproic acid+stool	Resistin	Caproic acid+stool-TCA+stool+16:0/18:2-PI+blood-20:1+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.882	0.156	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Resistin	Caproic acid+stool+Phenylacetic acid+stool-18:1/16:0-PC+blood+8-HETE+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.882	0.156	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Resistin	Caproic acid+stool+Phenylacetic acid+stool-20:3n6+blood-8-HETE+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.882	0.156	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Resistin	Caproic acid+stool+Phenylacetic acid+stool-16:0/16:1-PC+blood-8-HETE+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.882	0.156	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Resistin	Caproic acid+stool+Phenylacetic acid+stool-18:1/16:0-PC+blood-18:3n6+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.882	0.156	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Resistin	Caproic acid+stool+Phenylacetic acid+stool-16:0/18:2-PC+blood-18:3n6+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.882	0.156	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Resistin	Caproic acid+stool+Phenylacetic acid+stool-18:0/16:0-PC+blood-18:3n6+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.882	0.156	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Resistin	Caproic acid+stool+Phenylacetic acid+stool-18:1/16:0-PC+blood+UFA%+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.882	0.156	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Resistin	Caproic acid+stool+Phenylacetic acid+stool+d18:1-16:1-SM+blood-UFA%+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.882	0.156	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Resistin	Caproic acid+stool+Phenylacetic acid+stool-Cystine+blood+UFA%+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.882	0.156	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Resistin	Caproic acid+stool+Phenylacetic acid+stool-16:0/18:2-PC+blood+UFA%+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.882	0.156	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Resistin	Caproic acid+stool-GCA+stool+DPA+blood+UFA%+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.882	0.156	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Resistin	Caproic acid+stool+Indole-3-Acetic acid+stool-nutriCA+stool-13-HODE+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.882	0.156	no	no	no	no	no	no	DM-DS
Eggerthella	Resistin	Eggerthella-Yersinia infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.912	0.156	no	no	no	no	no	no	DM-DS
Eggerthella	Resistin	Eggerthella+Phosphatidylinositol signaling system+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.912	0.156	no	no	no	no	no	no	DM-DS
Eggerthella	Resistin	Eggerthella+nutriCA+stool-13-HODE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.912	0.156	no	no	no	no	no	no	DM-DS
Anaerotruncus	Resistin	Anaerotruncus-Ruminococcus+nutriCA+stool-13-HODE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.904	0.156	no	no	no	no	no	no	DM-DS
Anaerotruncus	Resistin	Anaerotruncus-Ruminococcus+20:2/18:0-PC+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.904	0.156	no	no	no	no	no	no	DM-DS
Anaerotruncus	Resistin	Anaerotruncus-Ruminococcus-18:2/16:0-PC+blood+8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.904	0.156	no	no	no	no	no	no	DM-DS
Anaerotruncus	Resistin	Anaerotruncus-Ruminococcus+18:0/20:3-PC+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.904	0.156	no	no	no	no	no	no	DM-DS
Anaerostipes	Resistin	Anaerostipes-Neutrophil extracellular trap formation+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.568	0.156	no	no	no	no	no	no	DM-DS
Anaerostipes	Resistin	Anaerostipes+RNA degradation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.568	0.156	no	no	no	no	no	no	DM-DS
Anaerostipes	Resistin	Anaerostipes+Spliceosome-Viral protein interaction with cytokine and cytokine receptor+Resistin	Indirect	Genus	DM-associated hormones	0.568	0.156	no	no	no	no	no	no	DM-DS
Anaerostipes	Resistin	Anaerostipes+RNA degradation-Viral protein interaction with cytokine and cytokine receptor+Resistin	Indirect	Genus	DM-associated hormones	0.568	0.156	no	no	no	no	no	no	DM-DS
TUDCA+stool	Resistin	TUDCA+stool-14:0/18:2-PC+blood-Creatinine+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.156	no	no	no	no	no	no	DM-DS
TUDCA+stool	Resistin	TUDCA+stool-d18:1-14:0-SM+blood-UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.156	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	Resistin	Isovaleric acid+stool+L-Phenylalanine+stool+L-Tryptophan+stool+Resistin	Indirect	stool_scfa	DM-associated hormones	0.343	0.156	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	Resistin	Isovaleric acid+stool+L-Phenylalanine+stool+8-HETE+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.343	0.156	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	Resistin	Isovaleric acid+stool+L-Phenylalanine+stool-18:3n6+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.343	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella+Wnt signaling pathway-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella-cGMP-PKG signaling pathway+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella+Protein processing in endoplasmic reticulum-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella-Fc gamma R-mediated phagocytosis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella-Biosynthesis of amino acids+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella+Inflammatory mediator regulation of TRP channels-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella-Nicotinate and nicotinamide metabolism+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella-Fc epsilon RI signaling pathway+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella-Peroxisome+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella-Epithelial cell signaling in Helicobacter pylori infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella-Olfactory transduction+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella+RNA degradation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella-IL-17 signaling pathway+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella+Ribosome biogenesis in eukaryotes-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella+Cell cycle-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella+Inflammatory mediator regulation of TRP channels+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella-cGMP-PKG signaling pathway+Viral protein interaction with cytokine and cytokine receptor+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella-Biosynthesis of amino acids+Viral protein interaction with cytokine and cytokine receptor+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella-Nicotinate and nicotinamide metabolism+Viral protein interaction with cytokine and cytokine receptor+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella+RNA degradation-Viral protein interaction with cytokine and cytokine receptor+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella-Arginine and proline metabolism+Viral protein interaction with cytokine and cytokine receptor+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
Paraprevotella	Resistin	Paraprevotella+Ribosome biogenesis in eukaryotes-Viral protein interaction with cytokine and cytokine receptor+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	Resistin	¦Ø-MCA+stool-L-Tryptophan+stool+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.156	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	Resistin	Phenylacetic acid+stool-16:0/18:2-PC+blood-18:3n6+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.156	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	Resistin	Phenylacetic acid+stool-18:1/16:0-PC+blood-18:3n6+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.156	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	Resistin	Phenylacetic acid+stool-18:0/16:0-PC+blood-18:3n6+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.156	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	Resistin	Phenylacetic acid+stool-16:0/18:2-PC+blood+UFA%+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.156	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	Resistin	Phenylacetic acid+stool+d18:1-16:1-SM+blood-UFA%+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.156	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	Resistin	Phenylacetic acid+stool-18:1/16:0-PC+blood+UFA%+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.156	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	Resistin	Phenylacetic acid+stool-Cystine+blood+UFA%+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.156	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	Resistin	Phenylacetic acid+stool-18:1/16:0-PC+blood+8-HETE+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.156	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	Resistin	Phenylacetic acid+stool-16:0/16:1-PC+blood-8-HETE+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.156	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	Resistin	Phenylacetic acid+stool-20:3n6+blood-8-HETE+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.156	no	no	no	no	no	no	DM-DS
Gemmiger	Resistin	Gemmiger+Central carbon metabolism in cancer-13-HODE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.595	0.156	no	no	no	no	no	no	DM-DS
Gemmiger	Resistin	Gemmiger+Colorectal cancer+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.595	0.156	no	no	no	no	no	no	DM-DS
Gemmiger	Resistin	Gemmiger+Central carbon metabolism in cancer+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.595	0.156	no	no	no	no	no	no	DM-DS
Gemmiger	Resistin	Gemmiger+Colorectal cancer-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.595	0.156	no	no	no	no	no	no	DM-DS
GDCA+stool	Resistin	GDCA+stool+L-Methionine+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.156	no	no	no	no	no	no	DM-DS
GDCA+stool	Resistin	GDCA+stool+L-Lysine+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.156	no	no	no	no	no	no	DM-DS
GDCA+stool	Resistin	GDCA+stool+L-Phenylalanine+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.156	no	no	no	no	no	no	DM-DS
Methanobrevibacter	Resistin	Methanobrevibacter-Cystine+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.629	0.156	no	no	no	no	no	no	DM-DS
Methanobrevibacter	Resistin	Methanobrevibacter+d18:1-14:0-SM+blood-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.629	0.156	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	Resistin	L-Tyrosine+stool-nutriCA+stool-13-HODE+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.156	no	no	no	no	no	no	DM-DS
CDCA+stool	Resistin	CDCA+stool+nutriCA+stool-13-HODE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.156	no	no	no	no	no	no	DM-DS
CDCA+stool	Resistin	CDCA+stool+20:3n6+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.156	no	no	no	no	no	no	DM-DS
CA+stool	Resistin	CA+stool+nutriCA+stool-13-HODE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.156	no	no	no	no	no	no	DM-DS
HDCA+blood	Resistin	HDCA+blood+Hypotaurine+blood+Taurine+blood+UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.156	no	no	no	no	no	no	DM-DS
HDCA+blood	Resistin	HDCA+blood+Hypotaurine+blood+L-Asparagine+blood+UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.156	no	no	no	no	no	no	DM-DS
HDCA+blood	Resistin	HDCA+blood+Hypotaurine+blood+PUFA/MUFA+blood+UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.156	no	no	no	no	no	no	DM-DS
UDCA+stool	Resistin	UDCA+stool-GDCA+blood+PUFA/MUFA+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-DS
UDCA+stool	Resistin	UDCA+stool+16:0/20:3-PC+blood+L-Lysine+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-DS
UDCA+stool	Resistin	UDCA+stool+16:0/20:3-PC+blood+18:1/16:0-PC+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-DS
UDCA+stool	Resistin	UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PG+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-DS
UDCA+stool	Resistin	UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PG+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-DS
UDCA+stool	Resistin	UDCA+stool+16:0/20:3-PC+blood+18:0/20:3-PC+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-DS
UDCA+stool	Resistin	UDCA+stool+16:0/20:3-PC+blood+18:1/16:0-PC+blood+8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-DS
UDCA+stool	Resistin	UDCA+stool+18:0/20:3-PI+blood+20:2/18:1-PE+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-DS
UDCA+stool	Resistin	UDCA+stool+16:0/20:3-PC+blood+20:2/18:0-PC+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-DS
UDCA+stool	Resistin	UDCA+stool+18:0/20:3-PI+blood+20:2/18:0-PC+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-DS
UDCA+stool	Resistin	UDCA+stool+16:0/20:3-PC+blood+20:3n6+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-DS
UDCA+stool	Resistin	UDCA+stool+18:0/20:3-PI+blood+20:3n6+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-DS
UDCA+stool	Resistin	UDCA+stool+16:0/20:3-PC+blood+18:1/16:0-PC+blood-18:3n6+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-DS
UDCA+stool	Resistin	UDCA+stool+16:0/20:3-PC+blood+18:0/16:0-PC+blood-18:3n6+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-DS
TDCA+stool	Resistin	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood-8-HETE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.156	no	no	no	no	no	no	DM-DS
TDCA+stool	Resistin	TDCA+stool-12-ketoDCA+blood+Ethanolamine+blood+UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.156	no	no	no	no	no	no	DM-DS
TDCA+stool	Resistin	TDCA+stool-d18:1-16:0-SM+blood+d18:1-16:1-SM+blood-UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.156	no	no	no	no	no	no	DM-DS
TDCA+stool	Resistin	TDCA+stool-12-ketoDCA+blood-18:1+blood+20:1+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Herpes simplex virus 1 infection-d18:1-16:1-SM+blood-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation+Type I diabetes mellitus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human T-cell leukemia virus 1 infection+Allograft rejection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human cytomegalovirus infection+Allograft rejection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human immunodeficiency virus 1 infection+Allograft rejection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation+Allograft rejection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Herpes simplex virus 1 infection+Allograft rejection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation+Pertussis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation+Pathogenic Escherichia coli infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation+Tuberculosis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation+Staphylococcus aureus infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation+Salmonella infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human T-cell leukemia virus 1 infection+Viral myocarditis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human cytomegalovirus infection+Viral myocarditis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human immunodeficiency virus 1 infection+Viral myocarditis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation+Viral myocarditis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Herpes simplex virus 1 infection+Viral myocarditis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human cytomegalovirus infection+Human papillomavirus infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human cytomegalovirus infection+Viral carcinogenesis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human immunodeficiency virus 1 infection+Viral carcinogenesis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human cytomegalovirus infection+Rheumatoid arthritis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human immunodeficiency virus 1 infection+Rheumatoid arthritis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation+Rheumatoid arthritis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation+Natural killer cell mediated cytotoxicity+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation-Cushing syndrome-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human T-cell leukemia virus 1 infection+Graft-versus-host disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human cytomegalovirus infection+Graft-versus-host disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human immunodeficiency virus 1 infection+Graft-versus-host disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation+Graft-versus-host disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Herpes simplex virus 1 infection+Graft-versus-host disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human T-cell leukemia virus 1 infection-Chemical carcinogenesis - receptor activation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human cytomegalovirus infection-Chemical carcinogenesis - receptor activation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human immunodeficiency virus 1 infection-Chemical carcinogenesis - receptor activation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation-Chemical carcinogenesis - receptor activation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Herpes simplex virus 1 infection-Chemical carcinogenesis - receptor activation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human T-cell leukemia virus 1 infection+Autoimmune thyroid disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human cytomegalovirus infection+Autoimmune thyroid disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human immunodeficiency virus 1 infection+Autoimmune thyroid disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation+Autoimmune thyroid disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Herpes simplex virus 1 infection+Autoimmune thyroid disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation-Colorectal cancer-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human T-cell leukemia virus 1 infection+Renal cell carcinoma+L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human cytomegalovirus infection+Renal cell carcinoma+L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human immunodeficiency virus 1 infection+Renal cell carcinoma+L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Herpes simplex virus 1 infection+Renal cell carcinoma+L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human T-cell leukemia virus 1 infection-DCA+stool-L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human cytomegalovirus infection-DCA+stool-L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human immunodeficiency virus 1 infection-DCA+stool-L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation-DCA+stool-L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Herpes simplex virus 1 infection-DCA+stool-L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation+Pathogenic Escherichia coli infection-18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation+Salmonella infection-18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation-Colorectal cancer+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation-GnRH signaling pathway+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Antigen processing and presentation+Pathogenic Escherichia coli infection+8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
Desulfovibrio	Resistin	Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.27	0.156	no	no	no	no	no	no	DM-DS
nutriCA+stool	Resistin	nutriCA+stool-13-HODE+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-d18:1-16:1-SM+blood-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation+Type I diabetes mellitus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+Allograft rejection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Allograft rejection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+Allograft rejection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation+Allograft rejection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+Allograft rejection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation+Pertussis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation+Pathogenic Escherichia coli infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation+Tuberculosis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation+Staphylococcus aureus infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation+Salmonella infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+Viral myocarditis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Viral myocarditis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+Viral myocarditis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation+Viral myocarditis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+Viral myocarditis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Human papillomavirus infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Viral carcinogenesis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+Viral carcinogenesis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Rheumatoid arthritis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+Rheumatoid arthritis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation+Rheumatoid arthritis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation+Natural killer cell mediated cytotoxicity+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation-Cushing syndrome-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+Graft-versus-host disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Graft-versus-host disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+Graft-versus-host disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation+Graft-versus-host disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+Graft-versus-host disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-Chemical carcinogenesis - receptor activation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human cytomegalovirus infection-Chemical carcinogenesis - receptor activation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-Chemical carcinogenesis - receptor activation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation-Chemical carcinogenesis - receptor activation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-Chemical carcinogenesis - receptor activation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+Autoimmune thyroid disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Autoimmune thyroid disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+Autoimmune thyroid disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation+Autoimmune thyroid disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+Autoimmune thyroid disease+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation-Colorectal cancer-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+Renal cell carcinoma+L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Renal cell carcinoma+L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+Renal cell carcinoma+L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+Renal cell carcinoma+L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-DCA+stool-L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human cytomegalovirus infection-DCA+stool-L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-DCA+stool-L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation-DCA+stool-L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-DCA+stool-L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation+Pathogenic Escherichia coli infection-18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation+Salmonella infection-18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation-Colorectal cancer+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation-GnRH signaling pathway+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Antigen processing and presentation+Pathogenic Escherichia coli infection+8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
Bilophila	Resistin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.528	0.156	no	no	no	no	no	no	DM-DS
GDCA+blood	Resistin	GDCA+blood+PUFA/MUFA+blood+UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.156	no	no	no	no	no	no	DM-DS
acetic acid C2+blood	Resistin	acetic acid C2+blood+d18:1-22:1-SM+blood-L-Glutamic acid+blood+UFA%+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.000193	0.156	up	dn	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	Resistin	isovaleric acid iso-C5+blood-L-Phenylalanine+blood+UFA%+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.117	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium-Platinum drug resistance-Viral protein interaction with cytokine and cytokine receptor+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium+nutriCA+stool-13-HODE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium-Relaxin signaling pathway+13-HODE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium-Gap junction+13-HODE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium-16:0/20:5-PC+blood-Creatinine+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium-DCA+stool-L-Tryptophan+stool+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium+Cysteine+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium+Long-term potentiation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium+L-Phenylalanine+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium+L-Methionine+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium+Lysosome+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium-Ethanolamine+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium+Salmonella infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium-PUFA/MUFA+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium+Tuberculosis+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium+Staphylococcus aureus infection+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium+Systemic lupus erythematosus+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium-Cushing syndrome-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium-Chemical carcinogenesis - receptor activation-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium-Endocrine resistance+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium+Salmonella infection-18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium-GnRH signaling pathway+18:3n6+blood-Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium+18:0/18:0-PS+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium+Oocyte meiosis-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium+20:3n6+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium+18:0/20:3-PC+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
Clostridium	Resistin	Clostridium+20:2/18:0-PC+blood-8-HETE+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	Resistin	T-¦Á-MCA+stool+TUDCA+stool-d18:1-14:0-SM+blood-UFA%+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.156	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	Resistin	T-¦Á-MCA+stool+TUDCA+stool-14:0/18:2-PC+blood-Creatinine+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.156	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	Resistin	12-ketoDCA+blood+Ethanolamine+blood+UFA%+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.156	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	Resistin	12-ketoDCA+blood-18:0/18:0-PS+blood-8-HETE+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.156	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	Resistin	12-ketoDCA+blood-18:1+blood+20:1+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.156	no	no	no	no	no	no	DM-DS
Butyricicoccus	Resistin	Butyricicoccus+TUDCA+stool-14:0/18:2-PC+blood-Creatinine+blood+Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	DM-DS
Butyricicoccus	Resistin	"Butyricicoccus+12,13-EPOME+blood-20:0+blood-Creatinine+blood+Resistin"	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	DM-DS
Butyricicoccus	Resistin	Butyricicoccus-18:2/20:4-PC+blood+20:0+blood-Creatinine+blood+Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	DM-DS
Butyricicoccus	Resistin	"Butyricicoccus+12,13-EPOME+blood-16:0/20:5-PG+blood+18:3n6+blood-Resistin"	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	DM-DS
Butyricicoccus	Resistin	Butyricicoccus-18:2/20:4-PC+blood-L-Phenylalanine+blood+UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	DM-DS
Butyricicoccus	Resistin	Butyricicoccus+TUDCA+stool-d18:1-14:0-SM+blood-UFA%+blood+Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	DM-DS
Butyricicoccus	Resistin	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood-20:1+blood+Resistin"	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	DM-DS
Butyricicoccus	Resistin	"Butyricicoccus+12,13-EPOME+blood-18:1-LPC+blood+20:1+blood+Resistin"	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	DM-DS
Blautia	Insulin	Blautia+L-Tryptophan+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	DM-DS
Blautia	Insulin	Blautia+L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	DM-DS
Blautia	Insulin	Blautia+CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	DM-DS
Blautia	Insulin	Blautia+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	DM-DS
Parabacteroides	Insulin	Parabacteroides-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	DM-DS
Dorea	Insulin	Dorea+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.00362	0.00058	up	no	dn	up	up	no	DM-DS
Dorea	Insulin	Dorea+GCDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.00362	0.00058	up	no	dn	up	up	no	DM-DS
Dorea	Insulin	Dorea+L-Tryptophan+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.00362	0.00058	up	no	dn	up	up	no	DM-DS
Dorea	Insulin	Dorea+L-Proline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.00362	0.00058	up	no	dn	up	up	no	DM-DS
Dorea	Insulin	Dorea+CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.00362	0.00058	up	no	dn	up	up	no	DM-DS
Dorea	Insulin	Dorea+L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.00362	0.00058	up	no	dn	up	up	no	DM-DS
Faecalibacterium	Insulin	Faecalibacterium-Phenylacetic acid+stool-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	DM-DS
Faecalibacterium	Insulin	Faecalibacterium+GCDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	DM-DS
TUDCA+blood	Insulin	TUDCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.00058	no	no	dn	up	up	no	DM-DS
Bacteroides	Insulin	Bacteroides-n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.000267	0.00058	dn	dn	up	up	up	no	DM-DS
Bacteroides	Insulin	Bacteroides-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.000267	0.00058	dn	dn	up	up	up	no	DM-DS
Bacteroides	Insulin	Bacteroides+Parabacteroides-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.000267	0.00058	dn	dn	up	up	up	no	DM-DS
Bacteroides	Insulin	Bacteroides+16:0/22:6-PC+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.000267	0.00058	dn	dn	up	up	up	no	DM-DS
Bacteroides	Insulin	Bacteroides+16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.000267	0.00058	dn	dn	up	up	up	no	DM-DS
Bacteroides	Insulin	Bacteroides+Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.000267	0.00058	dn	dn	up	up	up	no	DM-DS
Propionic acid+stool	Insulin	Propionic acid+stool-L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.00058	dn	no	up	up	up	no	DM-DS
[Ruminococcus]	Insulin	[Ruminococcus]+L-Proline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0679	0.00058	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	Insulin	[Ruminococcus]+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0679	0.00058	no	no	dn	up	up	no	DM-DS
GUDCA+blood	Insulin	GUDCA+blood+TUDCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.00058	no	no	dn	up	up	no	DM-DS
GUDCA+blood	Insulin	GUDCA+blood+HCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.00058	no	no	dn	up	up	no	DM-DS
GUDCA+blood	Insulin	GUDCA+blood+UDCA+blood+Eotaxin-IL-6-IP-10+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.00058	no	no	dn	up	up	no	DM-DS
UDCA+blood	Insulin	UDCA+blood+Eotaxin-IL-6-IP-10+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.0939	0.00058	no	no	dn	up	up	no	DM-DS
Acetic acid+stool	Insulin	Acetic acid+stool-16:0/18:0-PS+blood-n6/n3+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.00058	dn	no	no	up	up	no	DM-DS
Acetic acid+stool	Insulin	Acetic acid+stool-18:0/18:0-PS+blood-n6/n3+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.00058	dn	no	no	up	up	no	DM-DS
Acetic acid+stool	Insulin	Acetic acid+stool+L-Histidine+blood+n6/n3+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.00058	dn	no	no	up	up	no	DM-DS
Acetic acid+stool	Insulin	Acetic acid+stool-16:0/18:0-PS+blood+16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.00058	dn	no	no	up	up	no	DM-DS
Acetic acid+stool	Insulin	Acetic acid+stool+Butyric acid+stool-16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.00058	dn	no	no	up	up	no	DM-DS
Alistipes	Insulin	Alistipes-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0114	0.00058	no	up	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas-Creatinine+blood+L-Tryptophan+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas-L-Glutamine+blood+L-Tryptophan+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas+Cholinergic synapse-L-Tryptophan+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas-L-Methionine+blood+L-Tryptophan+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas-L-Isoleucine+blood+L-Tryptophan+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas+20:5n3+blood-n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas-L-Asparagine+blood+n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas+Cholinergic synapse-n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas-L-Isoleucine+blood+n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas+Cholinergic synapse+16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas-Butyric acid+stool-16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas+20:5n3+blood-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas-Creatinine+blood+L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas-L-Glutamine+blood+L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas+Cholinergic synapse-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas-L-Methionine+blood+L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas-L-Isoleucine+blood+L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas+Cholinergic synapse-L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas-L-Methionine+blood+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas-L-Isoleucine+blood+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Butyricimonas	Insulin	Butyricimonas-iso-DCA+blood-IP-10+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-DS
Collinsella	Insulin	Collinsella+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.128	0.00058	no	no	no	up	up	no	DM-DS
5-Hydroxytryptamine+urine	Insulin	5-Hydroxytryptamine+urine-Hippuric acid+urine-IL-6-IP-10+C-peptide+Insulin	Indirect	urine_cometabolism	DM-associated hormones	0.171	0.00058	no	no	no	up	up	no	DM-DS
Sarcina	Insulin	Sarcina+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0703	0.00058	no	no	no	up	up	no	DM-DS
Sarcina	Insulin	Sarcina+IP-10+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0703	0.00058	no	no	no	up	up	no	DM-DS
Sarcina	Insulin	Sarcina+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0703	0.00058	no	no	no	up	up	no	DM-DS
Methanosphaera	Insulin	Methanosphaera-Roseburia+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0703	0.00058	no	no	no	up	up	no	DM-DS
iso-DCA+stool	Insulin	iso-DCA+stool+Propionic acid+stool-L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.00058	no	no	no	up	up	no	DM-DS
LCA+stool	Insulin	LCA+stool-UDCA+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.00058	no	no	no	up	up	no	DM-DS
Akkermansia	Insulin	Akkermansia-Cholinergic synapse+16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.23	0.00058	no	no	no	up	up	no	DM-DS
Akkermansia	Insulin	Akkermansia-Cholinergic synapse-L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.23	0.00058	no	no	no	up	up	no	DM-DS
Akkermansia	Insulin	Akkermansia-Cholinergic synapse-L-Tryptophan+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.23	0.00058	no	no	no	up	up	no	DM-DS
Akkermansia	Insulin	Akkermansia-Cholinergic synapse-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.23	0.00058	no	no	no	up	up	no	DM-DS
Akkermansia	Insulin	Akkermansia-Cholinergic synapse-n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.23	0.00058	no	no	no	up	up	no	DM-DS
Akkermansia	Insulin	Akkermansia-Longevity regulating pathway-CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.23	0.00058	no	no	no	up	up	no	DM-DS
Bifidobacterium	Insulin	Bifidobacterium+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.105	0.00058	no	dn	no	up	up	no	DM-DS
3-Hydroxytyramine hydrochloride+urine	Insulin	3-Hydroxytyramine hydrochloride+urine-Hippuric acid+urine-IL-6-IP-10+C-peptide+Insulin	Indirect	urine_cometabolism	DM-associated hormones	0.288	0.00058	no	no	no	up	up	no	DM-DS
Ruminococcus	Insulin	Ruminococcus+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.335	0.00058	no	no	no	up	up	no	DM-DS
Ruminococcus	Insulin	Ruminococcus+IP-10+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.335	0.00058	no	no	no	up	up	no	DM-DS
GCDCA+blood	Insulin	GCDCA+blood+L-Tyrosine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.00058	no	no	no	up	up	no	DM-DS
GCDCA+blood	Insulin	GCDCA+blood+L-Proline+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.00058	no	no	no	up	up	no	DM-DS
ACA+blood	Insulin	ACA+blood-decanoic acid C10+blood+L-Phenylalanine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.00058	no	no	no	up	up	no	DM-DS
ACA+blood	Insulin	ACA+blood+EPA+blood-n6/n3+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.00058	no	no	no	up	up	no	DM-DS
ACA+blood	Insulin	ACA+blood-decanoic acid C10+blood+n6/n3+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.00058	no	no	no	up	up	no	DM-DS
DCA+stool	Insulin	DCA+stool-GCA+stool+GCDCA+stool+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.00058	no	no	no	up	up	no	DM-DS
DCA+stool	Insulin	DCA+stool-GCA+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.00058	no	no	no	up	up	no	DM-DS
Hippuric acid+urine	Insulin	Hippuric acid+urine-IL-6-IP-10+C-peptide+Insulin	Indirect	urine_cometabolism	DM-associated hormones	0.361	0.00058	no	no	no	up	up	no	DM-DS
Butyric acid+stool	Insulin	Butyric acid+stool-16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.102	0.00058	dn	no	no	up	up	no	DM-DS
4-hydroxybenzoic acid+stool	Insulin	4-hydroxybenzoic acid+stool-DCA+stool-GCA+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.00058	no	dn	no	up	up	no	DM-DS
4-hydroxybenzoic acid+stool	Insulin	4-hydroxybenzoic acid+stool-LCA+stool-UDCA+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.00058	no	dn	no	up	up	no	DM-DS
4-hydroxybenzoic acid+stool	Insulin	4-hydroxybenzoic acid+stool-iso-LCA+stool-UDCA+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.00058	no	dn	no	up	up	no	DM-DS
4-hydroxybenzoic acid+stool	Insulin	4-hydroxybenzoic acid+stool-iso-LCA+stool-TCA+stool-16:0/22:6-PC+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.00058	no	dn	no	up	up	no	DM-DS
4-hydroxybenzoic acid+stool	Insulin	4-hydroxybenzoic acid+stool-iso-LCA+stool-TCA+stool+L-Proline+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.00058	no	dn	no	up	up	no	DM-DS
4-hydroxybenzoic acid+stool	Insulin	4-hydroxybenzoic acid+stool-DCA+stool-GCA+stool+GCDCA+stool+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.00058	no	dn	no	up	up	no	DM-DS
4-hydroxybenzoic acid+stool	Insulin	4-hydroxybenzoic acid+stool+L-Tryptophan+stool+Homovanillic acid+urine-IP-10+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.00058	no	dn	no	up	up	no	DM-DS
Turicibacter	Insulin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.269	0.00058	no	no	no	up	up	no	DM-DS
Turicibacter	Insulin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.269	0.00058	no	no	no	up	up	no	DM-DS
Turicibacter	Insulin	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.269	0.00058	no	no	no	up	up	no	DM-DS
Turicibacter	Insulin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.269	0.00058	no	no	no	up	up	no	DM-DS
Turicibacter	Insulin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.269	0.00058	no	no	no	up	up	no	DM-DS
Turicibacter	Insulin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.269	0.00058	no	no	no	up	up	no	DM-DS
Turicibacter	Insulin	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.269	0.00058	no	no	no	up	up	no	DM-DS
GCA+blood	Insulin	GCA+blood+L-Proline+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.00058	no	no	no	up	up	no	DM-DS
ACA+stool	Insulin	ACA+stool-L-Phenylalanine+stool+Phenylacetic acid+stool-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.00058	no	no	no	up	up	no	DM-DS
CDCA+blood	Insulin	CDCA+blood+GCDCA+blood+L-Proline+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.00058	no	no	no	up	up	no	DM-DS
CDCA+blood	Insulin	CDCA+blood-Ethanolamine+blood+n6/n3+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.00058	no	no	no	up	up	no	DM-DS
CDCA+blood	Insulin	CDCA+blood+GCDCA+blood+L-Tyrosine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.00058	no	no	no	up	up	no	DM-DS
capric acid C6+blood	Insulin	capric acid C6+blood-HCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.433	0.00058	no	no	no	up	up	no	DM-DS
Prevotella	Insulin	Prevotella+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	DM-DS
TCA+blood	Insulin	TCA+blood+TUDCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.339	0.00058	no	no	no	up	up	no	DM-DS
iso-DCA+blood	Insulin	iso-DCA+blood-IP-10+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.00058	no	no	no	up	up	no	DM-DS
HCA+stool	Insulin	HCA+stool-HDCA+stool+L-2-Aminobutyric acid+blood-L-Proline+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.00058	no	no	no	up	up	no	DM-DS
Roseburia	Insulin	Roseburia+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.495	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+stool	Insulin	12-ketoDCA+stool+GCA+blood+L-Proline+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+stool	Insulin	12-ketoDCA+stool-GCA+stool+GCDCA+stool+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+stool	Insulin	12-ketoDCA+stool-GCA+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.00058	no	no	no	up	up	no	DM-DS
GLCA+blood	Insulin	GLCA+blood+TDCA+blood-IP-10+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.00058	no	no	no	up	up	no	DM-DS
L-Tryptophan+stool	Insulin	L-Tryptophan+stool+Homovanillic acid+urine-IP-10+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.00058	no	no	no	up	up	no	DM-DS
CA+blood	Insulin	CA+blood+GCDCA+blood+L-Tyrosine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.00058	no	no	no	up	up	no	DM-DS
CA+blood	Insulin	CA+blood+GCDCA+blood+L-Proline+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.00058	no	no	no	up	up	no	DM-DS
CA+blood	Insulin	CA+blood+GCA+blood+L-Proline+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.00058	no	no	no	up	up	no	DM-DS
CA+blood	Insulin	CA+blood+TDCA+blood-IP-10+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.00058	no	no	no	up	up	no	DM-DS
GUDCA+stool	Insulin	GUDCA+stool+12-HEPE+blood-L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.00058	no	dn	no	up	up	no	DM-DS
GUDCA+stool	Insulin	GUDCA+stool+12-HEPE+blood-L-Tryptophan+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.00058	no	dn	no	up	up	no	DM-DS
GUDCA+stool	Insulin	GUDCA+stool+12-HEPE+blood+16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.00058	no	dn	no	up	up	no	DM-DS
GUDCA+stool	Insulin	GUDCA+stool+12-HEPE+blood-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.00058	no	dn	no	up	up	no	DM-DS
L-Phenylalanine+stool	Insulin	L-Phenylalanine+stool+Phenylacetic acid+stool-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.00058	no	no	no	up	up	no	DM-DS
GCA+stool	Insulin	GCA+stool+GCDCA+stool+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.00058	no	no	no	up	up	no	DM-DS
GCA+stool	Insulin	GCA+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.00058	no	no	no	up	up	no	DM-DS
Coprococcus	Insulin	Coprococcus+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	DM-DS
Coprococcus	Insulin	Coprococcus+L-Tryptophan+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	DM-DS
Coprococcus	Insulin	Coprococcus+Roseburia+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Human cytomegalovirus infection+20:3n6+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+MAPK signaling pathway-20:3n6+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Shigellosis-16:0/22:6-PC+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+MAPK signaling pathway+16:0/22:6-PC+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+MAPK signaling pathway-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Thermogenesis-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Ribosome-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Prion disease-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Huntington disease-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Alzheimer disease-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Dopaminergic synapse-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Retrograde endocannabinoid signaling-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Human cytomegalovirus infection+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Renin secretion-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+Hepatitis B+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Vasopressin-regulated water reabsorption-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Melanogenesis-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Inflammatory mediator regulation of TRP channels-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Vascular smooth muscle contraction-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+Autophagy - animal+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Endocrine and other factor-regulated calcium reabsorption-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Circadian entrainment-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+NF-kappa B signaling pathway+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Pathways of neurodegeneration - multiple diseases-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Parkinson disease-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	"Oscillospira-Parathyroid hormone synthesis, secretion and action-Human papillomavirus infection+C-peptide+Insulin"	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Thermogenesis+Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+JAK-STAT signaling pathway-Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Ribosome+Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+Autophagy - animal-Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+NF-kappa B signaling pathway-Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Huntington disease+L-Proline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Alzheimer disease+L-Proline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Shigellosis+L-Proline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Vascular smooth muscle contraction+L-Proline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Diabetic cardiomyopathy+L-Proline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+MAPK signaling pathway-L-Proline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Oxidative phosphorylation+L-Proline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Pathways of neurodegeneration - multiple diseases+L-Proline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Cardiac muscle contraction+L-Proline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Parkinson disease+L-Proline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Thermogenesis-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+JAK-STAT signaling pathway+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Ribosome-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Dopaminergic synapse-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Retrograde endocannabinoid signaling-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Melanogenesis-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Inflammatory mediator regulation of TRP channels-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Vascular smooth muscle contraction-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+T cell receptor signaling pathway+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Platelet activation-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Oxidative phosphorylation-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+Autophagy - animal+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Circadian entrainment-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+NF-kappa B signaling pathway+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Cardiac muscle contraction-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+FoxO signaling pathway+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Focal adhesion-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+Progesterone-mediated oocyte maturation-n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Human cytomegalovirus infection+n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Shigellosis+n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+MAPK signaling pathway-n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+Progesterone-mediated oocyte maturation+16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira-Shigellosis-16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
Oscillospira	Insulin	Oscillospira+MAPK signaling pathway+16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-DS
HCA+blood	Insulin	HCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.544	0.00058	no	no	no	up	up	no	DM-DS
iso-LCA+stool	Insulin	iso-LCA+stool-TCA+stool+L-Proline+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.00058	no	no	no	up	up	no	DM-DS
iso-LCA+stool	Insulin	iso-LCA+stool-UDCA+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.00058	no	no	no	up	up	no	DM-DS
iso-LCA+stool	Insulin	iso-LCA+stool-TCA+stool-16:0/22:6-PC+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.00058	no	no	no	up	up	no	DM-DS
DCA+blood	Insulin	DCA+blood+L-Histidine+blood+n6/n3+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.00058	no	no	no	up	up	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	Insulin	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-d18:1-14:0-SM+blood-n6/n3+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.00058	no	no	no	up	up	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	Insulin	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood+16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.00058	no	no	no	up	up	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	Insulin	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.00058	no	no	no	up	up	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	Insulin	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Tryptophan+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.00058	no	no	no	up	up	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	Insulin	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.00058	no	no	no	up	up	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	Insulin	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-6-IP-10+C-peptide+Insulin"	Indirect	urine_cometabolism	DM-associated hormones	0.0125	0.00058	up	up	no	up	up	no	DM-DS
nutriCA+blood	Insulin	nutriCA+blood+UDCA+blood+Eotaxin-IL-6-IP-10+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.726	0.00058	no	no	no	up	up	no	DM-DS
4-hydroxybenzoic acid+urine	Insulin	4-hydroxybenzoic acid+urine+Homovanillic acid+urine-IP-10+C-peptide+Insulin	Indirect	urine_cometabolism	DM-associated hormones	0.52	0.00058	no	no	no	up	up	no	DM-DS
Indole-3-Acetic acid+stool	Insulin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.00058	no	no	no	up	up	no	DM-DS
TCA+stool	Insulin	TCA+stool+L-Proline+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.00058	no	no	no	up	up	no	DM-DS
TCA+stool	Insulin	TCA+stool-16:0/22:6-PC+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.00058	no	no	no	up	up	no	DM-DS
HDCA+stool	Insulin	HDCA+stool+L-2-Aminobutyric acid+blood-L-Proline+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-Progesterone-mediated oocyte maturation+16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Carbon metabolism+CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Proteasome+CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Hippo signaling pathway+CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-Progesterone-mediated oocyte maturation-n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-Cytosolic DNA-sensing pathway+n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+TCA+stool-16:0/22:6-PC+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+L-Methionine+blood+L-Tryptophan+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+TCA+stool+L-Proline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Vascular smooth muscle contraction+L-Proline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Proteasome+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-ErbB signaling pathway-L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+L-Methionine+blood+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Proteasome+Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Glycolysis / Gluconeogenesis+Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-Autophagy - animal-Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-RIG-I-like receptor signaling pathway-Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-ErbB signaling pathway-Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-TNF signaling pathway-Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-JAK-STAT signaling pathway-Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-NF-kappa B signaling pathway-Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Proteasome-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Adherens junction-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Platelet activation-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Glycolysis / Gluconeogenesis-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-T cell receptor signaling pathway+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-Autophagy - animal+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Regulation of actin cytoskeleton-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-RIG-I-like receptor signaling pathway+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Circadian entrainment-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Hippo signaling pathway-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Vascular smooth muscle contraction-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Tight junction-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-FoxO signaling pathway+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-ErbB signaling pathway+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-TNF signaling pathway+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-JAK-STAT signaling pathway+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Focal adhesion-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-NOD-like receptor signaling pathway+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-NF-kappa B signaling pathway+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-Signaling pathways regulating pluripotency of stem cells-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-ErbB signaling pathway-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+L-Methionine+blood+L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-Hepatitis B+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-Insulin resistance+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Renin secretion-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-Autophagy - animal+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-Cytosolic DNA-sensing pathway+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-RIG-I-like receptor signaling pathway+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Circadian entrainment-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira+Vascular smooth muscle contraction-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-TNF signaling pathway+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-NOD-like receptor signaling pathway+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Lachnospira	Insulin	Lachnospira-NF-kappa B signaling pathway+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-DS
Fusobacterium	Insulin	Fusobacterium-18:0/18:0-PC+blood+20:3n6+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.628	0.00058	no	no	no	up	up	no	DM-DS
Fusobacterium	Insulin	Fusobacterium-16:0/20:3-PC+blood+20:3n6+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.628	0.00058	no	no	no	up	up	no	DM-DS
Fusobacterium	Insulin	Fusobacterium-18:0/18:1-PC+blood+20:3n6+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.628	0.00058	no	no	no	up	up	no	DM-DS
Fusobacterium	Insulin	Fusobacterium-Intestinal immune network for IgA production+GCDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.628	0.00058	no	no	no	up	up	no	DM-DS
Fusobacterium	Insulin	Fusobacterium-18:0/18:0-PC+blood+IP-10+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.628	0.00058	no	no	no	up	up	no	DM-DS
Fusobacterium	Insulin	Fusobacterium-16:0/20:3-PC+blood+IP-10+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.628	0.00058	no	no	no	up	up	no	DM-DS
Fusobacterium	Insulin	Fusobacterium-18:0/18:1-PC+blood+IP-10+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.628	0.00058	no	no	no	up	up	no	DM-DS
Fusobacterium	Insulin	Fusobacterium-16:0/18:1-PC+blood+16:0/22:6-PC+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.628	0.00058	no	no	no	up	up	no	DM-DS
Fusobacterium	Insulin	Fusobacterium-Intestinal immune network for IgA production-Phenylacetic acid+stool-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.628	0.00058	no	no	no	up	up	no	DM-DS
GCDCA+stool	Insulin	GCDCA+stool+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.00058	no	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	Insulin	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.00058	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	Insulin	5-Hydroxytryptamine+stool-nutriCA+stool+20:3n6+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.00058	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	Insulin	5-Hydroxytryptamine+stool-UDCA+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.00058	dn	dn	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Necroptosis+n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Long-term depression+n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Ferroptosis+n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+Salmonella infection+L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Cushing syndrome-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Endocrine resistance-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Chemical carcinogenesis - receptor activation-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+GCA+stool+GCDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+CA+stool+CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Serotonergic synapse-CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+Salmonella infection+CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+Proteasome+CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Cocaine addiction-CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Regulation of lipolysis in adipocytes-CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Glutamatergic synapse-CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Insulin secretion-CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-GnRH signaling pathway-CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Cortisol synthesis and secretion-CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	"Odoribacter-Growth hormone synthesis, secretion and action-CDCA+stool+C-peptide+Insulin"	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Endocrine resistance-CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Chemical carcinogenesis - receptor activation-CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+Carbon metabolism+CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+CA+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Serotonergic synapse-L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+Proteasome+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+GCA+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	"Odoribacter-Growth hormone synthesis, secretion and action-L-Tyrosine+blood+C-peptide+Insulin"	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Gap junction-L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Chemical carcinogenesis - receptor activation-L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+Proteasome+Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+Glycolysis / Gluconeogenesis+Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Gap junction-Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Ferroptosis-Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+Longevity regulating pathway - multiple species+Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Ferroptosis-16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+Proteasome-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+Glycolysis / Gluconeogenesis-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+Neuroactive ligand-receptor interaction+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+Fc gamma R-mediated phagocytosis+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+Salmonella infection+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+Pathogenic Escherichia coli infection+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-GnRH signaling pathway-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Cushing syndrome-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter-Cortisol synthesis and secretion-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+Neuroactive ligand-receptor interaction+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Odoribacter	Insulin	Odoribacter+Fc gamma R-mediated phagocytosis+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-DS
Actinomyces	Insulin	Actinomyces+Coprococcus+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.621	0.00058	no	no	no	up	up	no	DM-DS
Actinomyces	Insulin	Actinomyces+Coprococcus+L-Tryptophan+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.621	0.00058	no	no	no	up	up	no	DM-DS
Actinomyces	Insulin	Actinomyces+Coprococcus+Roseburia+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.621	0.00058	no	no	no	up	up	no	DM-DS
Isobutyric acid+stool	Insulin	Isobutyric acid+stool+Phenylacetic acid+stool-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.408	0.00058	no	no	no	up	up	no	DM-DS
2-hydroxyphenylacetic acid+urine	Insulin	2-hydroxyphenylacetic acid+urine+Homovanillic acid+urine-IP-10+C-peptide+Insulin	Indirect	urine_cometabolism	DM-associated hormones	0.763	0.00058	no	no	no	up	up	no	DM-DS
Kynurenic acid+stool	Insulin	Kynurenic acid+stool+L-Phenylalanine+stool+Phenylacetic acid+stool-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.00058	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	Insulin	Kynurenic acid+stool-nutriCA+stool+20:3n6+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.00058	dn	dn	no	up	up	no	DM-DS
Caproic acid+stool	Insulin	Caproic acid+stool+Phenylacetic acid+stool-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.882	0.00058	no	no	no	up	up	no	DM-DS
Eggerthella	Insulin	Eggerthella-Yersinia infection+L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.912	0.00058	no	no	no	up	up	no	DM-DS
Eggerthella	Insulin	Eggerthella+Phosphatidylinositol signaling system-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.912	0.00058	no	no	no	up	up	no	DM-DS
Eggerthella	Insulin	Eggerthella-Influenza A+L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.912	0.00058	no	no	no	up	up	no	DM-DS
Eggerthella	Insulin	Eggerthella+nutriCA+stool+20:3n6+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.912	0.00058	no	no	no	up	up	no	DM-DS
Eggerthella	Insulin	Eggerthella+AMPK signaling pathway-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.912	0.00058	no	no	no	up	up	no	DM-DS
Eggerthella	Insulin	Eggerthella-Yersinia infection+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.912	0.00058	no	no	no	up	up	no	DM-DS
Eggerthella	Insulin	Eggerthella-Influenza A+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.912	0.00058	no	no	no	up	up	no	DM-DS
Eggerthella	Insulin	Eggerthella+AMPK signaling pathway-CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.912	0.00058	no	no	no	up	up	no	DM-DS
Anaerotruncus	Insulin	Anaerotruncus-Ruminococcus+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.904	0.00058	no	no	no	up	up	no	DM-DS
Anaerotruncus	Insulin	Anaerotruncus-Ruminococcus+IP-10+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.904	0.00058	no	no	no	up	up	no	DM-DS
Anaerostipes	Insulin	Anaerostipes-Neutrophil extracellular trap formation+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.568	0.00058	no	no	no	up	up	no	DM-DS
Anaerostipes	Insulin	Anaerostipes+RNA degradation-Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.568	0.00058	no	no	no	up	up	no	DM-DS
Anaerostipes	Insulin	Anaerostipes+L-2-Aminobutyric acid+blood-L-Proline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.568	0.00058	no	no	no	up	up	no	DM-DS
Anaerostipes	Insulin	Anaerostipes-Alcoholism-IP-10+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.568	0.00058	no	no	no	up	up	no	DM-DS
Anaerostipes	Insulin	Anaerostipes-TDCA+blood-IP-10+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.568	0.00058	no	no	no	up	up	no	DM-DS
Anaerostipes	Insulin	Anaerostipes-GDCA+blood-IP-10+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.568	0.00058	no	no	no	up	up	no	DM-DS
Anaerostipes	Insulin	Anaerostipes-IL-6-IP-10+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.568	0.00058	no	no	no	up	up	no	DM-DS
Anaerostipes	Insulin	Anaerostipes-Neutrophil extracellular trap formation+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.568	0.00058	no	no	no	up	up	no	DM-DS
Anaerostipes	Insulin	Anaerostipes+RNA degradation-Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.568	0.00058	no	no	no	up	up	no	DM-DS
Anaerostipes	Insulin	Anaerostipes+Propionic acid+stool-L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.568	0.00058	no	no	no	up	up	no	DM-DS
Anaerostipes	Insulin	Anaerostipes+RNA degradation+Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.568	0.00058	no	no	no	up	up	no	DM-DS
TUDCA+stool	Insulin	TUDCA+stool-d18:1-14:0-SM+blood-n6/n3+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.00058	no	no	no	up	up	no	DM-DS
Isovaleric acid+stool	Insulin	Isovaleric acid+stool+Phenylacetic acid+stool-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.343	0.00058	no	no	no	up	up	no	DM-DS
Paraprevotella	Insulin	Paraprevotella+IP-10+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.118	0.00058	no	no	no	up	up	no	DM-DS
Homovanillic acid+urine	Insulin	Homovanillic acid+urine-IP-10+C-peptide+Insulin	Indirect	urine_cometabolism	DM-associated hormones	0.45	0.00058	no	no	no	up	up	no	DM-DS
TDCA+blood	Insulin	TDCA+blood-IP-10+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.155	0.00058	no	up	no	up	up	no	DM-DS
¦Ø-MCA+stool	Insulin	¦Ø-MCA+stool+CDCA+stool+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.00058	no	no	no	up	up	no	DM-DS
Phenylacetic acid+stool	Insulin	Phenylacetic acid+stool-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.00058	no	no	no	up	up	no	DM-DS
Gemmiger	Insulin	Gemmiger+ErbB signaling pathway-L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.595	0.00058	no	no	no	up	up	no	DM-DS
Gemmiger	Insulin	Gemmiger+ErbB signaling pathway-Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.595	0.00058	no	no	no	up	up	no	DM-DS
Gemmiger	Insulin	Gemmiger+ErbB signaling pathway+Prolactin signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.595	0.00058	no	no	no	up	up	no	DM-DS
Gemmiger	Insulin	Gemmiger+Signaling pathways regulating pluripotency of stem cells-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.595	0.00058	no	no	no	up	up	no	DM-DS
Gemmiger	Insulin	Gemmiger+ErbB signaling pathway-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.595	0.00058	no	no	no	up	up	no	DM-DS
Gemmiger	Insulin	Gemmiger+Colorectal cancer-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.595	0.00058	no	no	no	up	up	no	DM-DS
Gemmiger	Insulin	Gemmiger+Gastric cancer-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.595	0.00058	no	no	no	up	up	no	DM-DS
GDCA+stool	Insulin	GDCA+stool-Phenylacetic acid+stool-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.00058	no	no	no	up	up	no	DM-DS
GDCA+stool	Insulin	GDCA+stool+L-Phenylalanine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.00058	no	no	no	up	up	no	DM-DS
GDCA+stool	Insulin	GDCA+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.00058	no	no	no	up	up	no	DM-DS
GDCA+stool	Insulin	GDCA+stool+IP-10+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.00058	no	no	no	up	up	no	DM-DS
GDCA+stool	Insulin	GDCA+stool+L-Tryptophan+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.00058	no	no	no	up	up	no	DM-DS
Methanobrevibacter	Insulin	Methanobrevibacter+Methanosphaera-Roseburia+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.629	0.00058	no	no	no	up	up	no	DM-DS
Methanobrevibacter	Insulin	Methanobrevibacter-Alcoholism-IP-10+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.629	0.00058	no	no	no	up	up	no	DM-DS
Methanobrevibacter	Insulin	Methanobrevibacter-Cystine+blood+n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.629	0.00058	no	no	no	up	up	no	DM-DS
Methanobrevibacter	Insulin	Methanobrevibacter+d18:1-14:0-SM+blood-n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.629	0.00058	no	no	no	up	up	no	DM-DS
Methanobrevibacter	Insulin	Methanobrevibacter-Cystine+blood+L-Tryptophan+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.629	0.00058	no	no	no	up	up	no	DM-DS
Methanobrevibacter	Insulin	Methanobrevibacter-Cystine+blood+L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.629	0.00058	no	no	no	up	up	no	DM-DS
L-Tyrosine+stool	Insulin	L-Tyrosine+stool-nutriCA+stool+20:3n6+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.00058	no	no	no	up	up	no	DM-DS
L-Tyrosine+stool	Insulin	L-Tyrosine+stool-18:2/20:4-PC+blood-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.00058	no	no	no	up	up	no	DM-DS
CDCA+stool	Insulin	CDCA+stool+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.00058	no	no	no	up	up	no	DM-DS
CA+stool	Insulin	CA+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.00058	no	no	no	up	up	no	DM-DS
CA+stool	Insulin	CA+stool+CDCA+stool+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.00058	no	no	no	up	up	no	DM-DS
HDCA+blood	Insulin	HDCA+blood+Hypotaurine+blood+n6/n3+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.00058	no	no	no	up	up	no	DM-DS
UDCA+stool	Insulin	UDCA+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood-n6/n3+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-d18:1-16:0-SM+blood+d18:1-20:0-SM+blood-n6/n3+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-16:0/22:6-PE+blood-n6/n3+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood+Ethanolamine+blood+n6/n3+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-HDCA+blood+Hypotaurine+blood+n6/n3+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-18:0/22:6-PI+blood-n6/n3+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-18:0/22:6-PE+blood-n6/n3+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-n6/n3+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood-16:0/22:6-PC+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood-16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood+16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PE+blood+L-Proline+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PE+blood+L-Proline+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood+L-Proline+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-d18:1-16:0-SM+blood+d18:1-20:1-SM+blood-L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-18:2/18:2-PS+blood+20:3n6+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-16:1/18:1-PG+blood+20:3n6+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PI+blood+20:3n6+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-18:0/20:3-PI+blood+20:3n6+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-18:1/16:1-PE+blood+20:3n6+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood+20:3n6+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood+20:3n6+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood+20:3n6+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood+d18:1-22:0-SM+blood+IP-10+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood+d18:0-24:1-SM+blood+IP-10+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood-20:4/18:0-PE+blood-IP-10+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
TDCA+stool	Insulin	TDCA+stool-12-ketoDCA+blood+GDCA+blood-IP-10+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	Insulin	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2-IP-10+C-peptide+Insulin	Indirect	urine_cometabolism	DM-associated hormones	0.973	0.00058	no	no	no	up	up	no	DM-DS
Desulfovibrio	Insulin	Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.27	0.00058	no	no	no	up	up	no	DM-DS
Desulfovibrio	Insulin	Desulfovibrio+Human cytomegalovirus infection+n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.27	0.00058	no	no	no	up	up	no	DM-DS
Desulfovibrio	Insulin	Desulfovibrio+Human immunodeficiency virus 1 infection+n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.27	0.00058	no	no	no	up	up	no	DM-DS
Desulfovibrio	Insulin	Desulfovibrio+Human cytomegalovirus infection+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.27	0.00058	no	no	no	up	up	no	DM-DS
Desulfovibrio	Insulin	Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.27	0.00058	no	no	no	up	up	no	DM-DS
Desulfovibrio	Insulin	Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.27	0.00058	no	no	no	up	up	no	DM-DS
Desulfovibrio	Insulin	Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.27	0.00058	no	no	no	up	up	no	DM-DS
nutriCA+stool	Insulin	nutriCA+stool+20:3n6+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.00058	no	no	no	up	up	no	DM-DS
Bilophila	Insulin	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.528	0.00058	no	no	no	up	up	no	DM-DS
Bilophila	Insulin	Bilophila+Desulfovibrio+Human cytomegalovirus infection+n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.528	0.00058	no	no	no	up	up	no	DM-DS
Bilophila	Insulin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+n6/n3+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.528	0.00058	no	no	no	up	up	no	DM-DS
Bilophila	Insulin	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Human papillomavirus infection+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.528	0.00058	no	no	no	up	up	no	DM-DS
Bilophila	Insulin	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.528	0.00058	no	no	no	up	up	no	DM-DS
Bilophila	Insulin	Bilophila+Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.528	0.00058	no	no	no	up	up	no	DM-DS
Bilophila	Insulin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.528	0.00058	no	no	no	up	up	no	DM-DS
GDCA+blood	Insulin	GDCA+blood-IP-10+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.00058	no	no	no	up	up	no	DM-DS
P-hydroxyhippuric acid+urine	Insulin	P-hydroxyhippuric acid+urine+Eotaxin-IL-6-IP-10+C-peptide+Insulin	Indirect	urine_cometabolism	DM-associated hormones	0.436	0.00058	no	no	no	up	up	no	DM-DS
acetic acid C2+blood	Insulin	acetic acid C2+blood+d18:1-20:1-SM+blood-L-Tyrosine+blood+C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.000193	0.00058	up	dn	no	up	up	no	DM-DS
isovaleric acid iso-C5+blood	Insulin	isovaleric acid iso-C5+blood-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.117	0.00058	no	no	no	up	up	no	DM-DS
Clostridium	Insulin	Clostridium+Long-term potentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.925	0.00058	no	no	no	up	up	no	DM-DS
Clostridium	Insulin	Clostridium+L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.925	0.00058	no	no	no	up	up	no	DM-DS
Clostridium	Insulin	Clostridium-16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.925	0.00058	no	no	no	up	up	no	DM-DS
Clostridium	Insulin	Clostridium+CDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.925	0.00058	no	no	no	up	up	no	DM-DS
Clostridium	Insulin	Clostridium+20:3n6+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.925	0.00058	no	no	no	up	up	no	DM-DS
T-¦Á-MCA+stool	Insulin	T-¦Á-MCA+stool-UDCA+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-18:1/18:1-PE+blood+20:3n6+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-16:0/18:1-PE+blood+20:3n6+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-18:1/18:0-PE+blood+20:3n6+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-18:1/16:1-PE+blood+20:3n6+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-18:2/18:2-PS+blood+20:3n6+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-18:0/18:1-PI+blood+20:3n6+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-16:1/18:1-PG+blood+20:3n6+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-18:0/20:3-PI+blood+20:3n6+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-18:1/18:0-PE+blood+L-Proline+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-18:0/18:1-PE+blood+L-Proline+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-18:0/18:0-PE+blood+L-Proline+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood+GDCA+blood-IP-10+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood+d18:0-24:1-SM+blood+IP-10+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-20:4/18:0-PE+blood-IP-10+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood+d18:1-22:0-SM+blood+IP-10+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-16:0/18:1-PE+blood-16:0/22:6-PC+blood-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-16:0/18:1-PE+blood-16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-16:0/18:0-PS+blood+16:0/20:5-PC+blood-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-18:0/18:0-PS+blood-n6/n3+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood+Ethanolamine+blood+n6/n3+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-18:0/22:6-PI+blood-n6/n3+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-16:0/18:0-PS+blood-n6/n3+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-16:0/22:6-PE+blood-n6/n3+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-18:0/22:6-PE+blood-n6/n3+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-DS
Butyricicoccus	Insulin	Butyricicoccus-18:2/20:4-PC+blood-L-Phenylalanine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-DS
Blautia	C-peptide	Blautia+L-Tryptophan+blood+C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	DM-DS
Blautia	C-peptide	Blautia+L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	DM-DS
Blautia	C-peptide	Blautia+CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	DM-DS
Blautia	C-peptide	Blautia+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	DM-DS
Parabacteroides	C-peptide	Parabacteroides-C-peptide	Direct	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	DM-DS
Dorea	C-peptide	Dorea+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.00362	0.228	up	no	dn	no	no	no	DM-DS
Dorea	C-peptide	Dorea+GCDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.00362	0.228	up	no	dn	no	no	no	DM-DS
Dorea	C-peptide	Dorea+L-Tryptophan+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.00362	0.228	up	no	dn	no	no	no	DM-DS
Dorea	C-peptide	Dorea+L-Proline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.00362	0.228	up	no	dn	no	no	no	DM-DS
Dorea	C-peptide	Dorea+CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.00362	0.228	up	no	dn	no	no	no	DM-DS
Dorea	C-peptide	Dorea+L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.00362	0.228	up	no	dn	no	no	no	DM-DS
Faecalibacterium	C-peptide	Faecalibacterium-Phenylacetic acid+stool-C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	C-peptide	Faecalibacterium+GCDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	DM-DS
TUDCA+blood	C-peptide	TUDCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.228	no	no	dn	no	no	no	DM-DS
Bacteroides	C-peptide	Bacteroides-n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.000267	0.228	dn	dn	up	no	no	no	DM-DS
Bacteroides	C-peptide	Bacteroides-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.000267	0.228	dn	dn	up	no	no	no	DM-DS
Bacteroides	C-peptide	Bacteroides+Parabacteroides-C-peptide	Indirect	Genus	DM-associated hormones	0.000267	0.228	dn	dn	up	no	no	no	DM-DS
Bacteroides	C-peptide	Bacteroides+16:0/22:6-PC+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.000267	0.228	dn	dn	up	no	no	no	DM-DS
Bacteroides	C-peptide	Bacteroides+16:0/20:5-PC+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.000267	0.228	dn	dn	up	no	no	no	DM-DS
Bacteroides	C-peptide	Bacteroides+Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.000267	0.228	dn	dn	up	no	no	no	DM-DS
Propionic acid+stool	C-peptide	Propionic acid+stool-L-Tyrosine+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0436	0.228	dn	no	up	no	no	no	DM-DS
[Ruminococcus]	C-peptide	[Ruminococcus]+L-Proline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0679	0.228	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	C-peptide	[Ruminococcus]+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0679	0.228	no	no	dn	no	no	no	DM-DS
GUDCA+blood	C-peptide	GUDCA+blood+TUDCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.228	no	no	dn	no	no	no	DM-DS
GUDCA+blood	C-peptide	GUDCA+blood+HCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.228	no	no	dn	no	no	no	DM-DS
GUDCA+blood	C-peptide	GUDCA+blood+UDCA+blood+Eotaxin-IL-6-IP-10+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.228	no	no	dn	no	no	no	DM-DS
UDCA+blood	C-peptide	UDCA+blood+Eotaxin-IL-6-IP-10+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.0939	0.228	no	no	dn	no	no	no	DM-DS
Acetic acid+stool	C-peptide	Acetic acid+stool-16:0/18:0-PS+blood-n6/n3+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0656	0.228	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	C-peptide	Acetic acid+stool-18:0/18:0-PS+blood-n6/n3+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0656	0.228	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	C-peptide	Acetic acid+stool+L-Histidine+blood+n6/n3+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0656	0.228	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	C-peptide	Acetic acid+stool-16:0/18:0-PS+blood+16:0/20:5-PC+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0656	0.228	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	C-peptide	Acetic acid+stool+Butyric acid+stool-16:0/20:5-PC+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0656	0.228	dn	no	no	no	no	no	DM-DS
Alistipes	C-peptide	Alistipes-L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0114	0.228	no	up	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas-Creatinine+blood+L-Tryptophan+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas-L-Glutamine+blood+L-Tryptophan+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas+Cholinergic synapse-L-Tryptophan+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas-L-Methionine+blood+L-Tryptophan+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas-L-Isoleucine+blood+L-Tryptophan+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas+20:5n3+blood-n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas-L-Asparagine+blood+n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas+Cholinergic synapse-n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas-L-Isoleucine+blood+n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas+Cholinergic synapse+16:0/20:5-PC+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas-Butyric acid+stool-16:0/20:5-PC+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas+20:5n3+blood-L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas-Creatinine+blood+L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas-L-Glutamine+blood+L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas+Cholinergic synapse-L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas-L-Methionine+blood+L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas-L-Isoleucine+blood+L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas+Cholinergic synapse-L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas-L-Methionine+blood+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas-L-Isoleucine+blood+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Butyricimonas	C-peptide	Butyricimonas-iso-DCA+blood-IP-10+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-DS
Collinsella	C-peptide	Collinsella+C-peptide	Direct	Genus	DM-associated hormones	0.128	0.228	no	no	no	no	no	no	DM-DS
5-Hydroxytryptamine+urine	C-peptide	5-Hydroxytryptamine+urine-Hippuric acid+urine-IL-6-IP-10+C-peptide	Indirect	urine_cometabolism	DM-associated hormones	0.171	0.228	no	no	no	no	no	no	DM-DS
Sarcina	C-peptide	Sarcina+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.0703	0.228	no	no	no	no	no	no	DM-DS
Sarcina	C-peptide	Sarcina+IP-10+C-peptide	Indirect	Genus	DM-associated hormones	0.0703	0.228	no	no	no	no	no	no	DM-DS
Sarcina	C-peptide	Sarcina+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.0703	0.228	no	no	no	no	no	no	DM-DS
Methanosphaera	C-peptide	Methanosphaera-Roseburia+C-peptide	Indirect	Genus	DM-associated hormones	0.0703	0.228	no	no	no	no	no	no	DM-DS
iso-DCA+stool	C-peptide	iso-DCA+stool+Propionic acid+stool-L-Tyrosine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.155	0.228	no	no	no	no	no	no	DM-DS
LCA+stool	C-peptide	LCA+stool-UDCA+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.314	0.228	no	no	no	no	no	no	DM-DS
Akkermansia	C-peptide	Akkermansia-Cholinergic synapse+16:0/20:5-PC+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.23	0.228	no	no	no	no	no	no	DM-DS
Akkermansia	C-peptide	Akkermansia-Cholinergic synapse-L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.23	0.228	no	no	no	no	no	no	DM-DS
Akkermansia	C-peptide	Akkermansia-Cholinergic synapse-L-Tryptophan+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.23	0.228	no	no	no	no	no	no	DM-DS
Akkermansia	C-peptide	Akkermansia-Cholinergic synapse-L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.23	0.228	no	no	no	no	no	no	DM-DS
Akkermansia	C-peptide	Akkermansia-Cholinergic synapse-n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.23	0.228	no	no	no	no	no	no	DM-DS
Akkermansia	C-peptide	Akkermansia-Longevity regulating pathway-CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.23	0.228	no	no	no	no	no	no	DM-DS
Bifidobacterium	C-peptide	Bifidobacterium+C-peptide	Direct	Genus	DM-associated hormones	0.105	0.228	no	dn	no	no	no	no	DM-DS
3-Hydroxytyramine hydrochloride+urine	C-peptide	3-Hydroxytyramine hydrochloride+urine-Hippuric acid+urine-IL-6-IP-10+C-peptide	Indirect	urine_cometabolism	DM-associated hormones	0.288	0.228	no	no	no	no	no	no	DM-DS
Ruminococcus	C-peptide	Ruminococcus+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.335	0.228	no	no	no	no	no	no	DM-DS
Ruminococcus	C-peptide	Ruminococcus+IP-10+C-peptide	Indirect	Genus	DM-associated hormones	0.335	0.228	no	no	no	no	no	no	DM-DS
GCDCA+blood	C-peptide	GCDCA+blood+L-Tyrosine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.31	0.228	no	no	no	no	no	no	DM-DS
GCDCA+blood	C-peptide	GCDCA+blood+L-Proline+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.31	0.228	no	no	no	no	no	no	DM-DS
ACA+blood	C-peptide	ACA+blood-decanoic acid C10+blood+L-Phenylalanine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.338	0.228	no	no	no	no	no	no	DM-DS
ACA+blood	C-peptide	ACA+blood+EPA+blood-n6/n3+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.338	0.228	no	no	no	no	no	no	DM-DS
ACA+blood	C-peptide	ACA+blood-decanoic acid C10+blood+n6/n3+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.338	0.228	no	no	no	no	no	no	DM-DS
DCA+stool	C-peptide	DCA+stool-GCA+stool+GCDCA+stool+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.195	0.228	no	no	no	no	no	no	DM-DS
DCA+stool	C-peptide	DCA+stool-GCA+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.195	0.228	no	no	no	no	no	no	DM-DS
Hippuric acid+urine	C-peptide	Hippuric acid+urine-IL-6-IP-10+C-peptide	Indirect	urine_cometabolism	DM-associated hormones	0.361	0.228	no	no	no	no	no	no	DM-DS
Butyric acid+stool	C-peptide	Butyric acid+stool-16:0/20:5-PC+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.102	0.228	dn	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	C-peptide	4-hydroxybenzoic acid+stool-DCA+stool-GCA+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.228	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	C-peptide	4-hydroxybenzoic acid+stool-LCA+stool-UDCA+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.228	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	C-peptide	4-hydroxybenzoic acid+stool-iso-LCA+stool-UDCA+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.228	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	C-peptide	4-hydroxybenzoic acid+stool-iso-LCA+stool-TCA+stool-16:0/22:6-PC+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.228	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	C-peptide	4-hydroxybenzoic acid+stool-iso-LCA+stool-TCA+stool+L-Proline+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.228	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	C-peptide	4-hydroxybenzoic acid+stool-DCA+stool-GCA+stool+GCDCA+stool+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.228	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	C-peptide	4-hydroxybenzoic acid+stool+L-Tryptophan+stool+Homovanillic acid+urine-IP-10+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.228	no	dn	no	no	no	no	DM-DS
Turicibacter	C-peptide	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.269	0.228	no	no	no	no	no	no	DM-DS
Turicibacter	C-peptide	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.269	0.228	no	no	no	no	no	no	DM-DS
Turicibacter	C-peptide	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.269	0.228	no	no	no	no	no	no	DM-DS
Turicibacter	C-peptide	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.269	0.228	no	no	no	no	no	no	DM-DS
Turicibacter	C-peptide	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.269	0.228	no	no	no	no	no	no	DM-DS
Turicibacter	C-peptide	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.269	0.228	no	no	no	no	no	no	DM-DS
Turicibacter	C-peptide	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.269	0.228	no	no	no	no	no	no	DM-DS
GCA+blood	C-peptide	GCA+blood+L-Proline+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.16	0.228	no	no	no	no	no	no	DM-DS
ACA+stool	C-peptide	ACA+stool-L-Phenylalanine+stool+Phenylacetic acid+stool-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.417	0.228	no	no	no	no	no	no	DM-DS
CDCA+blood	C-peptide	CDCA+blood+GCDCA+blood+L-Proline+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.506	0.228	no	no	no	no	no	no	DM-DS
CDCA+blood	C-peptide	CDCA+blood-Ethanolamine+blood+n6/n3+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.506	0.228	no	no	no	no	no	no	DM-DS
CDCA+blood	C-peptide	CDCA+blood+GCDCA+blood+L-Tyrosine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.506	0.228	no	no	no	no	no	no	DM-DS
capric acid C6+blood	C-peptide	capric acid C6+blood-HCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide	Indirect	serum_scfa	DM-associated hormones	0.433	0.228	no	no	no	no	no	no	DM-DS
Prevotella	C-peptide	Prevotella+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	DM-DS
TCA+blood	C-peptide	TCA+blood+TUDCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.339	0.228	no	no	no	no	no	no	DM-DS
iso-DCA+blood	C-peptide	iso-DCA+blood-IP-10+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.38	0.228	no	no	no	no	no	no	DM-DS
HCA+stool	C-peptide	HCA+stool-HDCA+stool+L-2-Aminobutyric acid+blood-L-Proline+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.155	0.228	no	no	no	no	no	no	DM-DS
Roseburia	C-peptide	Roseburia+C-peptide	Direct	Genus	DM-associated hormones	0.495	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	C-peptide	12-ketoDCA+stool+GCA+blood+L-Proline+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.505	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	C-peptide	12-ketoDCA+stool-GCA+stool+GCDCA+stool+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.505	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	C-peptide	12-ketoDCA+stool-GCA+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.505	0.228	no	no	no	no	no	no	DM-DS
GLCA+blood	C-peptide	GLCA+blood+TDCA+blood-IP-10+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.319	0.228	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	C-peptide	L-Tryptophan+stool+Homovanillic acid+urine-IP-10+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.228	no	no	no	no	no	no	DM-DS
CA+blood	C-peptide	CA+blood+GCDCA+blood+L-Tyrosine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.606	0.228	no	no	no	no	no	no	DM-DS
CA+blood	C-peptide	CA+blood+GCDCA+blood+L-Proline+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.606	0.228	no	no	no	no	no	no	DM-DS
CA+blood	C-peptide	CA+blood+GCA+blood+L-Proline+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.606	0.228	no	no	no	no	no	no	DM-DS
CA+blood	C-peptide	CA+blood+TDCA+blood-IP-10+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.606	0.228	no	no	no	no	no	no	DM-DS
GUDCA+stool	C-peptide	GUDCA+stool+12-HEPE+blood-L-Tyrosine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.228	no	dn	no	no	no	no	DM-DS
GUDCA+stool	C-peptide	GUDCA+stool+12-HEPE+blood-L-Tryptophan+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.228	no	dn	no	no	no	no	DM-DS
GUDCA+stool	C-peptide	GUDCA+stool+12-HEPE+blood+16:0/20:5-PC+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.228	no	dn	no	no	no	no	DM-DS
GUDCA+stool	C-peptide	GUDCA+stool+12-HEPE+blood-L-Phenylalanine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.228	no	dn	no	no	no	no	DM-DS
L-Phenylalanine+stool	C-peptide	L-Phenylalanine+stool+Phenylacetic acid+stool-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.228	no	no	no	no	no	no	DM-DS
GCA+stool	C-peptide	GCA+stool+GCDCA+stool+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.228	no	no	no	no	no	no	DM-DS
GCA+stool	C-peptide	GCA+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.228	no	no	no	no	no	no	DM-DS
Coprococcus	C-peptide	Coprococcus+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	DM-DS
Coprococcus	C-peptide	Coprococcus+L-Tryptophan+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	DM-DS
Coprococcus	C-peptide	Coprococcus+Roseburia+C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Human cytomegalovirus infection+20:3n6+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+MAPK signaling pathway-20:3n6+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Shigellosis-16:0/22:6-PC+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+MAPK signaling pathway+16:0/22:6-PC+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+MAPK signaling pathway-L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Thermogenesis-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Ribosome-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Prion disease-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Huntington disease-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Alzheimer disease-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Dopaminergic synapse-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Retrograde endocannabinoid signaling-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Human cytomegalovirus infection+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Renin secretion-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+Hepatitis B+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Vasopressin-regulated water reabsorption-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Melanogenesis-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Inflammatory mediator regulation of TRP channels-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Vascular smooth muscle contraction-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+Autophagy - animal+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Endocrine and other factor-regulated calcium reabsorption-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Circadian entrainment-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+NF-kappa B signaling pathway+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Pathways of neurodegeneration - multiple diseases-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Parkinson disease-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	"Oscillospira-Parathyroid hormone synthesis, secretion and action-Human papillomavirus infection+C-peptide"	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Thermogenesis+Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+JAK-STAT signaling pathway-Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Ribosome+Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+Autophagy - animal-Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+NF-kappa B signaling pathway-Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Huntington disease+L-Proline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Alzheimer disease+L-Proline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Shigellosis+L-Proline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Vascular smooth muscle contraction+L-Proline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Diabetic cardiomyopathy+L-Proline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+MAPK signaling pathway-L-Proline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Oxidative phosphorylation+L-Proline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Pathways of neurodegeneration - multiple diseases+L-Proline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Cardiac muscle contraction+L-Proline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Parkinson disease+L-Proline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Thermogenesis-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+JAK-STAT signaling pathway+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Ribosome-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Dopaminergic synapse-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Retrograde endocannabinoid signaling-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Melanogenesis-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Inflammatory mediator regulation of TRP channels-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Vascular smooth muscle contraction-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+T cell receptor signaling pathway+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Platelet activation-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Oxidative phosphorylation-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+Autophagy - animal+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Circadian entrainment-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+NF-kappa B signaling pathway+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Cardiac muscle contraction-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+FoxO signaling pathway+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Focal adhesion-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+Progesterone-mediated oocyte maturation-n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Human cytomegalovirus infection+n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Shigellosis+n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+MAPK signaling pathway-n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+Progesterone-mediated oocyte maturation+16:0/20:5-PC+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira-Shigellosis-16:0/20:5-PC+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
Oscillospira	C-peptide	Oscillospira+MAPK signaling pathway+16:0/20:5-PC+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-DS
HCA+blood	C-peptide	HCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.544	0.228	no	no	no	no	no	no	DM-DS
iso-LCA+stool	C-peptide	iso-LCA+stool-TCA+stool+L-Proline+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.72	0.228	no	no	no	no	no	no	DM-DS
iso-LCA+stool	C-peptide	iso-LCA+stool-UDCA+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.72	0.228	no	no	no	no	no	no	DM-DS
iso-LCA+stool	C-peptide	iso-LCA+stool-TCA+stool-16:0/22:6-PC+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.72	0.228	no	no	no	no	no	no	DM-DS
DCA+blood	C-peptide	DCA+blood+L-Histidine+blood+n6/n3+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.122	0.228	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	C-peptide	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-d18:1-14:0-SM+blood-n6/n3+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.228	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	C-peptide	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood+16:0/20:5-PC+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.228	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	C-peptide	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Tyrosine+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.228	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	C-peptide	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Tryptophan+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.228	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	C-peptide	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Phenylalanine+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.228	no	no	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	C-peptide	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-6-IP-10+C-peptide"	Indirect	urine_cometabolism	DM-associated hormones	0.0125	0.228	up	up	no	no	no	no	DM-DS
nutriCA+blood	C-peptide	nutriCA+blood+UDCA+blood+Eotaxin-IL-6-IP-10+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.726	0.228	no	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+urine	C-peptide	4-hydroxybenzoic acid+urine+Homovanillic acid+urine-IP-10+C-peptide	Indirect	urine_cometabolism	DM-associated hormones	0.52	0.228	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	C-peptide	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.228	no	no	no	no	no	no	DM-DS
TCA+stool	C-peptide	TCA+stool+L-Proline+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.458	0.228	no	no	no	no	no	no	DM-DS
TCA+stool	C-peptide	TCA+stool-16:0/22:6-PC+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.458	0.228	no	no	no	no	no	no	DM-DS
HDCA+stool	C-peptide	HDCA+stool+L-2-Aminobutyric acid+blood-L-Proline+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.176	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-Progesterone-mediated oocyte maturation+16:0/20:5-PC+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Carbon metabolism+CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Proteasome+CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Hippo signaling pathway+CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-Progesterone-mediated oocyte maturation-n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-Cytosolic DNA-sensing pathway+n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+TCA+stool-16:0/22:6-PC+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+L-Methionine+blood+L-Tryptophan+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+TCA+stool+L-Proline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Vascular smooth muscle contraction+L-Proline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Proteasome+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-ErbB signaling pathway-L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+L-Methionine+blood+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Proteasome+Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Glycolysis / Gluconeogenesis+Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-Autophagy - animal-Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-RIG-I-like receptor signaling pathway-Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-ErbB signaling pathway-Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-TNF signaling pathway-Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-JAK-STAT signaling pathway-Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-NF-kappa B signaling pathway-Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Proteasome-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Adherens junction-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Platelet activation-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Glycolysis / Gluconeogenesis-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-T cell receptor signaling pathway+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-Autophagy - animal+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Regulation of actin cytoskeleton-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-RIG-I-like receptor signaling pathway+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Circadian entrainment-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Hippo signaling pathway-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Vascular smooth muscle contraction-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Tight junction-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-FoxO signaling pathway+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-ErbB signaling pathway+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-TNF signaling pathway+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-JAK-STAT signaling pathway+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Focal adhesion-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-NOD-like receptor signaling pathway+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-NF-kappa B signaling pathway+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-Signaling pathways regulating pluripotency of stem cells-L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-ErbB signaling pathway-L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+L-Methionine+blood+L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-Hepatitis B+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-Insulin resistance+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Renin secretion-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-Autophagy - animal+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-Cytosolic DNA-sensing pathway+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-RIG-I-like receptor signaling pathway+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Circadian entrainment-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira+Vascular smooth muscle contraction-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-TNF signaling pathway+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-NOD-like receptor signaling pathway+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Lachnospira	C-peptide	Lachnospira-NF-kappa B signaling pathway+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-DS
Fusobacterium	C-peptide	Fusobacterium-18:0/18:0-PC+blood+20:3n6+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.628	0.228	no	no	no	no	no	no	DM-DS
Fusobacterium	C-peptide	Fusobacterium-16:0/20:3-PC+blood+20:3n6+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.628	0.228	no	no	no	no	no	no	DM-DS
Fusobacterium	C-peptide	Fusobacterium-18:0/18:1-PC+blood+20:3n6+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.628	0.228	no	no	no	no	no	no	DM-DS
Fusobacterium	C-peptide	Fusobacterium-Intestinal immune network for IgA production+GCDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.628	0.228	no	no	no	no	no	no	DM-DS
Fusobacterium	C-peptide	Fusobacterium-18:0/18:0-PC+blood+IP-10+C-peptide	Indirect	Genus	DM-associated hormones	0.628	0.228	no	no	no	no	no	no	DM-DS
Fusobacterium	C-peptide	Fusobacterium-16:0/20:3-PC+blood+IP-10+C-peptide	Indirect	Genus	DM-associated hormones	0.628	0.228	no	no	no	no	no	no	DM-DS
Fusobacterium	C-peptide	Fusobacterium-18:0/18:1-PC+blood+IP-10+C-peptide	Indirect	Genus	DM-associated hormones	0.628	0.228	no	no	no	no	no	no	DM-DS
Fusobacterium	C-peptide	Fusobacterium-16:0/18:1-PC+blood+16:0/22:6-PC+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.628	0.228	no	no	no	no	no	no	DM-DS
Fusobacterium	C-peptide	Fusobacterium-Intestinal immune network for IgA production-Phenylacetic acid+stool-C-peptide	Indirect	Genus	DM-associated hormones	0.628	0.228	no	no	no	no	no	no	DM-DS
GCDCA+stool	C-peptide	GCDCA+stool+C-peptide	Direct	stool_bileacids	DM-associated hormones	0.0471	0.228	no	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	C-peptide	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.228	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	C-peptide	5-Hydroxytryptamine+stool-nutriCA+stool+20:3n6+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.228	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	C-peptide	5-Hydroxytryptamine+stool-UDCA+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.228	dn	dn	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Necroptosis+n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Long-term depression+n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Ferroptosis+n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+Salmonella infection+L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Cushing syndrome-L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Endocrine resistance-L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Chemical carcinogenesis - receptor activation-L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+GCA+stool+GCDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+CA+stool+CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Serotonergic synapse-CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+Salmonella infection+CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+Proteasome+CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Cocaine addiction-CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Regulation of lipolysis in adipocytes-CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Glutamatergic synapse-CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Insulin secretion-CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-GnRH signaling pathway-CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Cortisol synthesis and secretion-CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	"Odoribacter-Growth hormone synthesis, secretion and action-CDCA+stool+C-peptide"	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Endocrine resistance-CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Chemical carcinogenesis - receptor activation-CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+Carbon metabolism+CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+CA+stool+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Serotonergic synapse-L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+Proteasome+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+GCA+stool+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	"Odoribacter-Growth hormone synthesis, secretion and action-L-Tyrosine+blood+C-peptide"	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Gap junction-L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Chemical carcinogenesis - receptor activation-L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+Proteasome+Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+Glycolysis / Gluconeogenesis+Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Gap junction-Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Ferroptosis-Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+Longevity regulating pathway - multiple species+Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Ferroptosis-16:0/20:5-PC+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+Proteasome-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+Glycolysis / Gluconeogenesis-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+Neuroactive ligand-receptor interaction+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+Fc gamma R-mediated phagocytosis+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+Salmonella infection+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+Pathogenic Escherichia coli infection+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-GnRH signaling pathway-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Cushing syndrome-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter-Cortisol synthesis and secretion-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+Neuroactive ligand-receptor interaction+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Odoribacter	C-peptide	Odoribacter+Fc gamma R-mediated phagocytosis+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-DS
Actinomyces	C-peptide	Actinomyces+Coprococcus+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.621	0.228	no	no	no	no	no	no	DM-DS
Actinomyces	C-peptide	Actinomyces+Coprococcus+L-Tryptophan+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.621	0.228	no	no	no	no	no	no	DM-DS
Actinomyces	C-peptide	Actinomyces+Coprococcus+Roseburia+C-peptide	Indirect	Genus	DM-associated hormones	0.621	0.228	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	C-peptide	Isobutyric acid+stool+Phenylacetic acid+stool-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.408	0.228	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	C-peptide	2-hydroxyphenylacetic acid+urine+Homovanillic acid+urine-IP-10+C-peptide	Indirect	urine_cometabolism	DM-associated hormones	0.763	0.228	no	no	no	no	no	no	DM-DS
Kynurenic acid+stool	C-peptide	Kynurenic acid+stool+L-Phenylalanine+stool+Phenylacetic acid+stool-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.228	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	C-peptide	Kynurenic acid+stool-nutriCA+stool+20:3n6+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.228	dn	dn	no	no	no	no	DM-DS
Caproic acid+stool	C-peptide	Caproic acid+stool+Phenylacetic acid+stool-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.882	0.228	no	no	no	no	no	no	DM-DS
Eggerthella	C-peptide	Eggerthella-Yersinia infection+L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.912	0.228	no	no	no	no	no	no	DM-DS
Eggerthella	C-peptide	Eggerthella+Phosphatidylinositol signaling system-L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.912	0.228	no	no	no	no	no	no	DM-DS
Eggerthella	C-peptide	Eggerthella-Influenza A+L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.912	0.228	no	no	no	no	no	no	DM-DS
Eggerthella	C-peptide	Eggerthella+nutriCA+stool+20:3n6+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.912	0.228	no	no	no	no	no	no	DM-DS
Eggerthella	C-peptide	Eggerthella+AMPK signaling pathway-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.912	0.228	no	no	no	no	no	no	DM-DS
Eggerthella	C-peptide	Eggerthella-Yersinia infection+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.912	0.228	no	no	no	no	no	no	DM-DS
Eggerthella	C-peptide	Eggerthella-Influenza A+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.912	0.228	no	no	no	no	no	no	DM-DS
Eggerthella	C-peptide	Eggerthella+AMPK signaling pathway-CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.912	0.228	no	no	no	no	no	no	DM-DS
Anaerotruncus	C-peptide	Anaerotruncus-Ruminococcus+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.904	0.228	no	no	no	no	no	no	DM-DS
Anaerotruncus	C-peptide	Anaerotruncus-Ruminococcus+IP-10+C-peptide	Indirect	Genus	DM-associated hormones	0.904	0.228	no	no	no	no	no	no	DM-DS
Anaerostipes	C-peptide	Anaerostipes-Neutrophil extracellular trap formation+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.568	0.228	no	no	no	no	no	no	DM-DS
Anaerostipes	C-peptide	Anaerostipes+RNA degradation-Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.568	0.228	no	no	no	no	no	no	DM-DS
Anaerostipes	C-peptide	Anaerostipes+L-2-Aminobutyric acid+blood-L-Proline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.568	0.228	no	no	no	no	no	no	DM-DS
Anaerostipes	C-peptide	Anaerostipes-Alcoholism-IP-10+C-peptide	Indirect	Genus	DM-associated hormones	0.568	0.228	no	no	no	no	no	no	DM-DS
Anaerostipes	C-peptide	Anaerostipes-TDCA+blood-IP-10+C-peptide	Indirect	Genus	DM-associated hormones	0.568	0.228	no	no	no	no	no	no	DM-DS
Anaerostipes	C-peptide	Anaerostipes-GDCA+blood-IP-10+C-peptide	Indirect	Genus	DM-associated hormones	0.568	0.228	no	no	no	no	no	no	DM-DS
Anaerostipes	C-peptide	Anaerostipes-IL-6-IP-10+C-peptide	Indirect	Genus	DM-associated hormones	0.568	0.228	no	no	no	no	no	no	DM-DS
Anaerostipes	C-peptide	Anaerostipes-Neutrophil extracellular trap formation+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.568	0.228	no	no	no	no	no	no	DM-DS
Anaerostipes	C-peptide	Anaerostipes+RNA degradation-Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.568	0.228	no	no	no	no	no	no	DM-DS
Anaerostipes	C-peptide	Anaerostipes+Propionic acid+stool-L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.568	0.228	no	no	no	no	no	no	DM-DS
Anaerostipes	C-peptide	Anaerostipes+RNA degradation+Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.568	0.228	no	no	no	no	no	no	DM-DS
TUDCA+stool	C-peptide	TUDCA+stool-d18:1-14:0-SM+blood-n6/n3+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.241	0.228	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	C-peptide	Isovaleric acid+stool+Phenylacetic acid+stool-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.343	0.228	no	no	no	no	no	no	DM-DS
Paraprevotella	C-peptide	Paraprevotella+IP-10+C-peptide	Indirect	Genus	DM-associated hormones	0.118	0.228	no	no	no	no	no	no	DM-DS
Homovanillic acid+urine	C-peptide	Homovanillic acid+urine-IP-10+C-peptide	Indirect	urine_cometabolism	DM-associated hormones	0.45	0.228	no	no	no	no	no	no	DM-DS
TDCA+blood	C-peptide	TDCA+blood-IP-10+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.155	0.228	no	up	no	no	no	no	DM-DS
¦Ø-MCA+stool	C-peptide	¦Ø-MCA+stool+CDCA+stool+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.919	0.228	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	C-peptide	Phenylacetic acid+stool-C-peptide	Direct	stool_cometabolism	DM-associated hormones	0.785	0.228	no	no	no	no	no	no	DM-DS
Gemmiger	C-peptide	Gemmiger+ErbB signaling pathway-L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.595	0.228	no	no	no	no	no	no	DM-DS
Gemmiger	C-peptide	Gemmiger+ErbB signaling pathway-Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.595	0.228	no	no	no	no	no	no	DM-DS
Gemmiger	C-peptide	Gemmiger+ErbB signaling pathway+Prolactin signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.595	0.228	no	no	no	no	no	no	DM-DS
Gemmiger	C-peptide	Gemmiger+Signaling pathways regulating pluripotency of stem cells-L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.595	0.228	no	no	no	no	no	no	DM-DS
Gemmiger	C-peptide	Gemmiger+ErbB signaling pathway-L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.595	0.228	no	no	no	no	no	no	DM-DS
Gemmiger	C-peptide	Gemmiger+Colorectal cancer-L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.595	0.228	no	no	no	no	no	no	DM-DS
Gemmiger	C-peptide	Gemmiger+Gastric cancer-L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.595	0.228	no	no	no	no	no	no	DM-DS
GDCA+stool	C-peptide	GDCA+stool-Phenylacetic acid+stool-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.656	0.228	no	no	no	no	no	no	DM-DS
GDCA+stool	C-peptide	GDCA+stool+L-Phenylalanine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.656	0.228	no	no	no	no	no	no	DM-DS
GDCA+stool	C-peptide	GDCA+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.656	0.228	no	no	no	no	no	no	DM-DS
GDCA+stool	C-peptide	GDCA+stool+IP-10+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.656	0.228	no	no	no	no	no	no	DM-DS
GDCA+stool	C-peptide	GDCA+stool+L-Tryptophan+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.656	0.228	no	no	no	no	no	no	DM-DS
Methanobrevibacter	C-peptide	Methanobrevibacter+Methanosphaera-Roseburia+C-peptide	Indirect	Genus	DM-associated hormones	0.629	0.228	no	no	no	no	no	no	DM-DS
Methanobrevibacter	C-peptide	Methanobrevibacter-Alcoholism-IP-10+C-peptide	Indirect	Genus	DM-associated hormones	0.629	0.228	no	no	no	no	no	no	DM-DS
Methanobrevibacter	C-peptide	Methanobrevibacter-Cystine+blood+n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.629	0.228	no	no	no	no	no	no	DM-DS
Methanobrevibacter	C-peptide	Methanobrevibacter+d18:1-14:0-SM+blood-n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.629	0.228	no	no	no	no	no	no	DM-DS
Methanobrevibacter	C-peptide	Methanobrevibacter-Cystine+blood+L-Tryptophan+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.629	0.228	no	no	no	no	no	no	DM-DS
Methanobrevibacter	C-peptide	Methanobrevibacter-Cystine+blood+L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.629	0.228	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	C-peptide	L-Tyrosine+stool-nutriCA+stool+20:3n6+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.228	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	C-peptide	L-Tyrosine+stool-18:2/20:4-PC+blood-L-Phenylalanine+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.228	no	no	no	no	no	no	DM-DS
CDCA+stool	C-peptide	CDCA+stool+C-peptide	Direct	stool_bileacids	DM-associated hormones	0.663	0.228	no	no	no	no	no	no	DM-DS
CA+stool	C-peptide	CA+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.827	0.228	no	no	no	no	no	no	DM-DS
CA+stool	C-peptide	CA+stool+CDCA+stool+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.827	0.228	no	no	no	no	no	no	DM-DS
HDCA+blood	C-peptide	HDCA+blood+Hypotaurine+blood+n6/n3+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.483	0.228	no	no	no	no	no	no	DM-DS
UDCA+stool	C-peptide	UDCA+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.266	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood-n6/n3+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-d18:1-16:0-SM+blood+d18:1-20:0-SM+blood-n6/n3+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-16:0/22:6-PE+blood-n6/n3+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood+Ethanolamine+blood+n6/n3+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-HDCA+blood+Hypotaurine+blood+n6/n3+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-18:0/22:6-PI+blood-n6/n3+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-18:0/22:6-PE+blood-n6/n3+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-n6/n3+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood-16:0/22:6-PC+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood-16:0/20:5-PC+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood+16:0/20:5-PC+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PE+blood+L-Proline+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PE+blood+L-Proline+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood+L-Proline+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-d18:1-16:0-SM+blood+d18:1-20:1-SM+blood-L-Tyrosine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-18:2/18:2-PS+blood+20:3n6+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-16:1/18:1-PG+blood+20:3n6+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PI+blood+20:3n6+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-18:0/20:3-PI+blood+20:3n6+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-18:1/16:1-PE+blood+20:3n6+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood+20:3n6+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood+20:3n6+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood+20:3n6+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood+d18:1-22:0-SM+blood+IP-10+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood+d18:0-24:1-SM+blood+IP-10+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood-20:4/18:0-PE+blood-IP-10+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
TDCA+stool	C-peptide	TDCA+stool-12-ketoDCA+blood+GDCA+blood-IP-10+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	C-peptide	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2-IP-10+C-peptide	Indirect	urine_cometabolism	DM-associated hormones	0.973	0.228	no	no	no	no	no	no	DM-DS
Desulfovibrio	C-peptide	Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.27	0.228	no	no	no	no	no	no	DM-DS
Desulfovibrio	C-peptide	Desulfovibrio+Human cytomegalovirus infection+n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.27	0.228	no	no	no	no	no	no	DM-DS
Desulfovibrio	C-peptide	Desulfovibrio+Human immunodeficiency virus 1 infection+n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.27	0.228	no	no	no	no	no	no	DM-DS
Desulfovibrio	C-peptide	Desulfovibrio+Human cytomegalovirus infection+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.27	0.228	no	no	no	no	no	no	DM-DS
Desulfovibrio	C-peptide	Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.27	0.228	no	no	no	no	no	no	DM-DS
Desulfovibrio	C-peptide	Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.27	0.228	no	no	no	no	no	no	DM-DS
Desulfovibrio	C-peptide	Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.27	0.228	no	no	no	no	no	no	DM-DS
nutriCA+stool	C-peptide	nutriCA+stool+20:3n6+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.481	0.228	no	no	no	no	no	no	DM-DS
Bilophila	C-peptide	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.528	0.228	no	no	no	no	no	no	DM-DS
Bilophila	C-peptide	Bilophila+Desulfovibrio+Human cytomegalovirus infection+n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.528	0.228	no	no	no	no	no	no	DM-DS
Bilophila	C-peptide	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+n6/n3+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.528	0.228	no	no	no	no	no	no	DM-DS
Bilophila	C-peptide	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Human papillomavirus infection+C-peptide	Indirect	Genus	DM-associated hormones	0.528	0.228	no	no	no	no	no	no	DM-DS
Bilophila	C-peptide	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.528	0.228	no	no	no	no	no	no	DM-DS
Bilophila	C-peptide	Bilophila+Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.528	0.228	no	no	no	no	no	no	DM-DS
Bilophila	C-peptide	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.528	0.228	no	no	no	no	no	no	DM-DS
GDCA+blood	C-peptide	GDCA+blood-IP-10+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.632	0.228	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	C-peptide	P-hydroxyhippuric acid+urine+Eotaxin-IL-6-IP-10+C-peptide	Indirect	urine_cometabolism	DM-associated hormones	0.436	0.228	no	no	no	no	no	no	DM-DS
acetic acid C2+blood	C-peptide	acetic acid C2+blood+d18:1-20:1-SM+blood-L-Tyrosine+blood+C-peptide	Indirect	serum_scfa	DM-associated hormones	0.000193	0.228	up	dn	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	C-peptide	isovaleric acid iso-C5+blood-L-Phenylalanine+blood+C-peptide	Indirect	serum_scfa	DM-associated hormones	0.117	0.228	no	no	no	no	no	no	DM-DS
Clostridium	C-peptide	Clostridium+Long-term potentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.925	0.228	no	no	no	no	no	no	DM-DS
Clostridium	C-peptide	Clostridium+L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.925	0.228	no	no	no	no	no	no	DM-DS
Clostridium	C-peptide	Clostridium-16:0/20:5-PC+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.925	0.228	no	no	no	no	no	no	DM-DS
Clostridium	C-peptide	Clostridium+CDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.925	0.228	no	no	no	no	no	no	DM-DS
Clostridium	C-peptide	Clostridium+20:3n6+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.925	0.228	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	C-peptide	T-¦Á-MCA+stool-UDCA+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.48	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-18:1/18:1-PE+blood+20:3n6+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-16:0/18:1-PE+blood+20:3n6+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-18:1/18:0-PE+blood+20:3n6+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-18:1/16:1-PE+blood+20:3n6+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-18:2/18:2-PS+blood+20:3n6+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-18:0/18:1-PI+blood+20:3n6+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-16:1/18:1-PG+blood+20:3n6+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-18:0/20:3-PI+blood+20:3n6+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-18:1/18:0-PE+blood+L-Proline+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-18:0/18:1-PE+blood+L-Proline+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-18:0/18:0-PE+blood+L-Proline+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood+GDCA+blood-IP-10+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood+d18:0-24:1-SM+blood+IP-10+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-20:4/18:0-PE+blood-IP-10+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood+d18:1-22:0-SM+blood+IP-10+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-16:0/18:1-PE+blood-16:0/22:6-PC+blood-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-16:0/18:1-PE+blood-16:0/20:5-PC+blood-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-16:0/18:0-PS+blood+16:0/20:5-PC+blood-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-18:0/18:0-PS+blood-n6/n3+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood+Ethanolamine+blood+n6/n3+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-18:0/22:6-PI+blood-n6/n3+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-16:0/18:0-PS+blood-n6/n3+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-16:0/22:6-PE+blood-n6/n3+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-18:0/22:6-PE+blood-n6/n3+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-DS
Butyricicoccus	C-peptide	Butyricicoccus-18:2/20:4-PC+blood-L-Phenylalanine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-DS
Blautia	FGF basic	Blautia+Longevity regulating pathway - multiple species-Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia+Longevity regulating pathway - multiple species+Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia+Peroxisome+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia+d18:1-18:0-SM+blood+n3+blood-FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia-Calcium signaling pathway-n3+blood-FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia+Peroxisome+B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia+Peroxisome+Apoptosis+FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia+Peroxisome+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia-Dopaminergic synapse-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia+Peroxisome-Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia-Dopaminergic synapse+Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia+Peroxisome+Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia-Dopaminergic synapse-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia-Dopaminergic synapse-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia+Longevity regulating pathway - multiple species-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia-Dopaminergic synapse-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia+CDCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia-Dopaminergic synapse-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia-Calcium signaling pathway-16:1/16:1-PC+blood-FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Blautia	FGF basic	Blautia-Calcium signaling pathway-18:3n3+blood-FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-DS
Parabacteroides	FGF basic	Parabacteroides-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	4.19E-05	0.65	no	up	up	no	no	no	DM-DS
Dorea	FGF basic	Dorea+Glycolysis / Gluconeogenesis-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-DS
Dorea	FGF basic	Dorea+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-DS
Dorea	FGF basic	Dorea+Glycolysis / Gluconeogenesis-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-DS
Dorea	FGF basic	Dorea+Glycolysis / Gluconeogenesis-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-DS
Dorea	FGF basic	Dorea+Glycolysis / Gluconeogenesis-Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-DS
Dorea	FGF basic	Dorea+Glycolysis / Gluconeogenesis-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-DS
Dorea	FGF basic	Dorea+Glycolysis / Gluconeogenesis-Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-DS
Dorea	FGF basic	Dorea+Carbon metabolism-Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-DS
Dorea	FGF basic	Dorea+Glycolysis / Gluconeogenesis-Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-DS
Dorea	FGF basic	Dorea+Glycolysis / Gluconeogenesis-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-DS
Dorea	FGF basic	Dorea+Glycolysis / Gluconeogenesis-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-DS
Dorea	FGF basic	Dorea+Glycolysis / Gluconeogenesis-Apoptosis+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-DS
Dorea	FGF basic	Dorea+GCDCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-DS
Dorea	FGF basic	Dorea+CDCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-DS
Dorea	FGF basic	Dorea+Glycolysis / Gluconeogenesis-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-DS
Dorea	FGF basic	Dorea+Glycolysis / Gluconeogenesis-cAMP signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-DS
Faecalibacterium	FGF basic	Faecalibacterium-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0039	0.65	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	FGF basic	Faecalibacterium+GCDCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0039	0.65	no	dn	dn	no	no	no	DM-DS
Bacteroides	FGF basic	Bacteroides-Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-DS
Bacteroides	FGF basic	Bacteroides-cAMP signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-DS
Bacteroides	FGF basic	Bacteroides+16:1/16:1-PC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-DS
Bacteroides	FGF basic	Bacteroides-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-DS
Bacteroides	FGF basic	Bacteroides-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-DS
Bacteroides	FGF basic	Bacteroides-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-DS
Bacteroides	FGF basic	Bacteroides-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-DS
Propionic acid+stool	FGF basic	Propionic acid+stool-16:0/16:0-PC+blood-18:0-LPC+blood-18:3n3+blood-FGF basic	Indirect	stool_scfa	serum_cytokines	0.0436	0.65	dn	no	up	no	no	no	DM-DS
Propionic acid+stool	FGF basic	Propionic acid+stool-16:0/16:0-PC+blood+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_scfa	serum_cytokines	0.0436	0.65	dn	no	up	no	no	no	DM-DS
Propionic acid+stool	FGF basic	Propionic acid+stool-16:0/16:0-PC+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_scfa	serum_cytokines	0.0436	0.65	dn	no	up	no	no	no	DM-DS
Propionic acid+stool	FGF basic	Propionic acid+stool+d18:1-20:1-SM+blood-decanoic acid C10+blood-n3+blood-FGF basic	Indirect	stool_scfa	serum_cytokines	0.0436	0.65	dn	no	up	no	no	no	DM-DS
Propionic acid+stool	FGF basic	Propionic acid+stool+18:0-LPE+blood-20:5-LPC+blood+n3+blood-FGF basic	Indirect	stool_scfa	serum_cytokines	0.0436	0.65	dn	no	up	no	no	no	DM-DS
Propionic acid+stool	FGF basic	Propionic acid+stool-16:0/16:0-PC+blood+22:0/16:0-PE+blood+n3+blood-FGF basic	Indirect	stool_scfa	serum_cytokines	0.0436	0.65	dn	no	up	no	no	no	DM-DS
Propionic acid+stool	FGF basic	Propionic acid+stool+18:0-LPE+blood-22:0/16:0-PE+blood+n3+blood-FGF basic	Indirect	stool_scfa	serum_cytokines	0.0436	0.65	dn	no	up	no	no	no	DM-DS
Propionic acid+stool	FGF basic	Propionic acid+stool-16:0/16:0-PC+blood+18:0/18:2-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_scfa	serum_cytokines	0.0436	0.65	dn	no	up	no	no	no	DM-DS
Propionic acid+stool	FGF basic	Propionic acid+stool+18:0-LPE+blood-18:0/18:2-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_scfa	serum_cytokines	0.0436	0.65	dn	no	up	no	no	no	DM-DS
Propionic acid+stool	FGF basic	Propionic acid+stool-16:0/16:0-PC+blood+18:1/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_scfa	serum_cytokines	0.0436	0.65	dn	no	up	no	no	no	DM-DS
Propionic acid+stool	FGF basic	Propionic acid+stool+18:0-LPE+blood-18:1/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_scfa	serum_cytokines	0.0436	0.65	dn	no	up	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Shigellosis-n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-18:0/20:4-PC+blood+n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-18:1/20:4-PC+blood+n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-18:0/20:5-PC+blood+n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Tight junction-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-ErbB signaling pathway+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-JAK-STAT signaling pathway+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-MicroRNAs in cancer+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-Pathways in cancer+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-ErbB signaling pathway-Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-ErbB signaling pathway+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-JAK-STAT signaling pathway+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Huntington disease-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Non-alcoholic fatty liver disease-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-MicroRNAs in cancer+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-Pathways in cancer+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Alzheimer disease-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Parkinson disease-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-ErbB signaling pathway+Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-JAK-STAT signaling pathway+Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-JAK-STAT signaling pathway+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Huntington disease-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Non-alcoholic fatty liver disease-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Alzheimer disease-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Parkinson disease-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Tight junction-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-JAK-STAT signaling pathway+Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells-16:1/16:1-PC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-Gastric cancer-16:1/16:1-PC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-Platinum drug resistance+Ribosome biogenesis in eukaryotes-FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Tight junction-Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-ErbB signaling pathway+Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-JAK-STAT signaling pathway+Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-FoxO signaling pathway+Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-ErbB signaling pathway+Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-JAK-STAT signaling pathway+Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Tight junction-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-ErbB signaling pathway+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-JAK-STAT signaling pathway+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-MicroRNAs in cancer+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-Pathways in cancer+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Tight junction-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-ErbB signaling pathway+B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-JAK-STAT signaling pathway+B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Tight junction-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-FoxO signaling pathway+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-ErbB signaling pathway+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-JAK-STAT signaling pathway+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Huntington disease-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Non-alcoholic fatty liver disease-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-MicroRNAs in cancer+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-Pathways in cancer+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Alzheimer disease-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Parkinson disease-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-18:0/20:4-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+18:0/18:1-PE+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Tight junction-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-FoxO signaling pathway+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-ErbB signaling pathway+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-JAK-STAT signaling pathway+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Huntington disease-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]+Alzheimer disease-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-Progesterone-mediated oocyte maturation+Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-Platinum drug resistance+Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	FGF basic	[Ruminococcus]-Progesterone-mediated oocyte maturation-18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-DS
Acetic acid+stool	FGF basic	Acetic acid+stool-16:0/18:0-PS+blood+n3+blood-FGF basic	Indirect	stool_scfa	serum_cytokines	0.0656	0.65	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	FGF basic	Acetic acid+stool-18:0/18:0-PS+blood+n3+blood-FGF basic	Indirect	stool_scfa	serum_cytokines	0.0656	0.65	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	FGF basic	Acetic acid+stool+L-Histidine+blood-n3+blood-FGF basic	Indirect	stool_scfa	serum_cytokines	0.0656	0.65	dn	no	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Vibrio cholerae infection-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+T cell receptor signaling pathway+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Platelet activation-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Ferroptosis+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+Platinum drug resistance+Ribosome biogenesis in eukaryotes-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Influenza A-Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+MAPK signaling pathway+Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+Platinum drug resistance+Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Rap1 signaling pathway-Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Ferroptosis-Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Ferroptosis+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Ferroptosis+Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+T cell receptor signaling pathway+B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-18:2/16:0-PC+blood+18:3n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+18:0-LPC+blood-18:3n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+T cell receptor signaling pathway-Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Vibrio cholerae infection-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+T cell receptor signaling pathway+Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Platelet activation-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Oxytocin signaling pathway-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Salivary secretion-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Alcoholism+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Ferroptosis+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Vibrio cholerae infection-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+T cell receptor signaling pathway+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+Signaling pathways regulating pluripotency of stem cells+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Platelet activation-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Oxytocin signaling pathway-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Salivary secretion-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+Colorectal cancer-16:1/16:1-PC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+Signaling pathways regulating pluripotency of stem cells-16:1/16:1-PC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+Gastric cancer-16:1/16:1-PC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+T cell receptor signaling pathway+Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Platelet activation-Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+MAPK signaling pathway-18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Vibrio cholerae infection-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+T cell receptor signaling pathway+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+Signaling pathways regulating pluripotency of stem cells+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Platelet activation-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Oxytocin signaling pathway-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Rap1 signaling pathway-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Salivary secretion-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Vibrio cholerae infection-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+T cell receptor signaling pathway+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+Signaling pathways regulating pluripotency of stem cells+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Platelet activation-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Oxytocin signaling pathway-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-Salivary secretion-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes+MAPK signaling pathway+n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Alistipes	FGF basic	Alistipes-DMG+blood-n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-DS
Butyricimonas	FGF basic	Butyricimonas+Cholinergic synapse-18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.17	0.65	no	no	no	no	no	no	DM-DS
Butyricimonas	FGF basic	Butyricimonas+20:5n3+blood+n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.17	0.65	no	no	no	no	no	no	DM-DS
Butyricimonas	FGF basic	Butyricimonas+Cholinergic synapse+n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.17	0.65	no	no	no	no	no	no	DM-DS
Collinsella	FGF basic	Collinsella-Renin secretion-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-DS
Collinsella	FGF basic	Collinsella-Inflammatory mediator regulation of TRP channels-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-DS
Collinsella	FGF basic	Collinsella-Renin secretion-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-DS
Collinsella	FGF basic	Collinsella-Inflammatory mediator regulation of TRP channels-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-DS
Collinsella	FGF basic	Collinsella-Inflammatory mediator regulation of TRP channels+Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-DS
Collinsella	FGF basic	Collinsella-Renin secretion-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-DS
Collinsella	FGF basic	Collinsella-Inflammatory mediator regulation of TRP channels-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-DS
Collinsella	FGF basic	Collinsella-Renin secretion-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-DS
Collinsella	FGF basic	Collinsella-Inflammatory mediator regulation of TRP channels-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-DS
Collinsella	FGF basic	Collinsella-Renin secretion-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-DS
Collinsella	FGF basic	Collinsella-Inflammatory mediator regulation of TRP channels-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-DS
Collinsella	FGF basic	Collinsella-Renin secretion-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-DS
Collinsella	FGF basic	Collinsella-Inflammatory mediator regulation of TRP channels-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-DS
Collinsella	FGF basic	Collinsella-Renin secretion-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-DS
Collinsella	FGF basic	Collinsella-Inflammatory mediator regulation of TRP channels-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-DS
Sarcina	FGF basic	Sarcina+FGF basic	Direct	Genus	serum_cytokines	0.0703	0.65	no	no	no	no	no	no	DM-DS
Methanosphaera	FGF basic	Methanosphaera-Roseburia+16:0/16:1-PC+blood-18:3n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0703	0.65	no	no	no	no	no	no	DM-DS
Methanosphaera	FGF basic	Methanosphaera-Roseburia+16:0/16:1-PC+blood-n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0703	0.65	no	no	no	no	no	no	DM-DS
Methanosphaera	FGF basic	Methanosphaera-Roseburia+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.0703	0.65	no	no	no	no	no	no	DM-DS
Methanosphaera	FGF basic	Methanosphaera-Roseburia+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.0703	0.65	no	no	no	no	no	no	DM-DS
Methanosphaera	FGF basic	Methanosphaera-Roseburia+16:0/16:1-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0703	0.65	no	no	no	no	no	no	DM-DS
Methanosphaera	FGF basic	Methanosphaera-Roseburia+GCDCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0703	0.65	no	no	no	no	no	no	DM-DS
Methanosphaera	FGF basic	Methanosphaera-Roseburia-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0703	0.65	no	no	no	no	no	no	DM-DS
iso-DCA+stool	FGF basic	iso-DCA+stool+Propionic acid+stool-16:0/16:0-PC+blood-18:0-LPC+blood-18:3n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.155	0.65	no	no	no	no	no	no	DM-DS
iso-DCA+stool	FGF basic	iso-DCA+stool+Propionic acid+stool-16:0/16:0-PC+blood+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.155	0.65	no	no	no	no	no	no	DM-DS
iso-DCA+stool	FGF basic	iso-DCA+stool+Propionic acid+stool-16:0/16:0-PC+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.155	0.65	no	no	no	no	no	no	DM-DS
iso-DCA+stool	FGF basic	iso-DCA+stool+Propionic acid+stool+d18:1-20:1-SM+blood-decanoic acid C10+blood-n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.155	0.65	no	no	no	no	no	no	DM-DS
iso-DCA+stool	FGF basic	iso-DCA+stool+Propionic acid+stool+18:0-LPE+blood-20:5-LPC+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.155	0.65	no	no	no	no	no	no	DM-DS
iso-DCA+stool	FGF basic	iso-DCA+stool+Propionic acid+stool-16:0/16:0-PC+blood+22:0/16:0-PE+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.155	0.65	no	no	no	no	no	no	DM-DS
iso-DCA+stool	FGF basic	iso-DCA+stool+Propionic acid+stool+18:0-LPE+blood-22:0/16:0-PE+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.155	0.65	no	no	no	no	no	no	DM-DS
iso-DCA+stool	FGF basic	iso-DCA+stool+Propionic acid+stool-16:0/16:0-PC+blood+18:0/18:2-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.155	0.65	no	no	no	no	no	no	DM-DS
iso-DCA+stool	FGF basic	iso-DCA+stool+Propionic acid+stool+18:0-LPE+blood-18:0/18:2-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.155	0.65	no	no	no	no	no	no	DM-DS
iso-DCA+stool	FGF basic	iso-DCA+stool+Propionic acid+stool-16:0/16:0-PC+blood+18:1/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.155	0.65	no	no	no	no	no	no	DM-DS
iso-DCA+stool	FGF basic	iso-DCA+stool+Propionic acid+stool+18:0-LPE+blood-18:1/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.155	0.65	no	no	no	no	no	no	DM-DS
LCA+stool	FGF basic	LCA+stool-UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.314	0.65	no	no	no	no	no	no	DM-DS
LCA+stool	FGF basic	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.314	0.65	no	no	no	no	no	no	DM-DS
LCA+stool	FGF basic	LCA+stool-UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.314	0.65	no	no	no	no	no	no	DM-DS
Akkermansia	FGF basic	Akkermansia+Proteoglycans in cancer-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	DM-DS
Akkermansia	FGF basic	Akkermansia-Cholinergic synapse-18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	DM-DS
Akkermansia	FGF basic	Akkermansia-Cholinergic synapse+n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	DM-DS
Akkermansia	FGF basic	Akkermansia-Cytokine-cytokine receptor interaction+16:1/16:1-PC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	DM-DS
Akkermansia	FGF basic	Akkermansia+Proteoglycans in cancer-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	DM-DS
Akkermansia	FGF basic	Akkermansia-Cytokine-cytokine receptor interaction-Cytosolic DNA-sensing pathway+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Glutamatergic synapse+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Gastric acid secretion-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Autophagy - animal+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+HIF-1 signaling pathway-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Proteasome-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-GABAergic synapse+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Proteoglycans in cancer-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Transcriptional misregulation in cancer+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Hepatitis B+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Glycolysis / Gluconeogenesis-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-MicroRNAs in cancer+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Focal adhesion-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Hippo signaling pathway-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Autophagy - animal+B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+HIF-1 signaling pathway-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Proteasome-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Tight junction-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Glycolysis / Gluconeogenesis-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Focal adhesion-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Hippo signaling pathway-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Adherens junction-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Autophagy - animal+Apoptosis+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+HIF-1 signaling pathway-Apoptosis+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Proteasome-Apoptosis+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Glycolysis / Gluconeogenesis-Apoptosis+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Autophagy - animal+Cytosolic DNA-sensing pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Focal adhesion-Cytosolic DNA-sensing pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Autophagy - animal+Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+HIF-1 signaling pathway-Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Proteasome-Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-FoxO signaling pathway+Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Glycolysis / Gluconeogenesis-Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Focal adhesion-Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Hippo signaling pathway-Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Adherens junction-Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Autophagy - animal+Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Proteasome-Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Tight junction-Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Glycolysis / Gluconeogenesis-Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Focal adhesion-Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Hippo signaling pathway-Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Adherens junction-Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-18:0/20:4-PI+blood+n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+DMG+blood-n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Glutamatergic synapse+Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Autophagy - animal+Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+HIF-1 signaling pathway-Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Proteasome-Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Glycolysis / Gluconeogenesis-Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Focal adhesion-Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Hippo signaling pathway-Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Vibrio cholerae infection-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Gastric acid secretion-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Autophagy - animal+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Proteasome-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Transcriptional misregulation in cancer+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Tight junction-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Hepatitis B+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Bacterial invasion of epithelial cells-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Glycolysis / Gluconeogenesis-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-MicroRNAs in cancer+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Focal adhesion-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Hippo signaling pathway-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Adherens junction-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Vibrio cholerae infection-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Gastric acid secretion-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Autophagy - animal+Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Tight junction-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Focal adhesion-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Hippo signaling pathway-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Adherens junction-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Vibrio cholerae infection-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Gastric acid secretion-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Autophagy - animal+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Proteasome-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Transcriptional misregulation in cancer+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Tight junction-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Hepatitis B+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Bacterial invasion of epithelial cells-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Glycolysis / Gluconeogenesis-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-MicroRNAs in cancer+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Focal adhesion-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Hippo signaling pathway-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Adherens junction-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Vibrio cholerae infection-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Thyroid hormone signaling pathway-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Gastric acid secretion-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Autophagy - animal+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+HIF-1 signaling pathway-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Proteasome-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-GABAergic synapse+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-FoxO signaling pathway+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Proteoglycans in cancer-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Transcriptional misregulation in cancer+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Tight junction-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Hepatitis B+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Bacterial invasion of epithelial cells-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Glycolysis / Gluconeogenesis-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-MicroRNAs in cancer+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Focal adhesion-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Hippo signaling pathway-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Adherens junction-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Proteasome-cAMP signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Glycolysis / Gluconeogenesis-cAMP signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Autophagy - animal-Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Proteasome+Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-GABAergic synapse-Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Focal adhesion+Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Hippo signaling pathway+Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Glutamatergic synapse+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Autophagy - animal+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+HIF-1 signaling pathway-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Proteasome-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-GABAergic synapse+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Glycolysis / Gluconeogenesis-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Hippo signaling pathway-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Leukocyte transendothelial migration-Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Glutamatergic synapse+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Vibrio cholerae infection-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Thyroid hormone signaling pathway-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Gastric acid secretion-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-Autophagy - animal+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+HIF-1 signaling pathway-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Proteasome-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-GABAergic synapse+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium-FoxO signaling pathway+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Tight junction-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Bacterial invasion of epithelial cells-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Glycolysis / Gluconeogenesis-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Focal adhesion-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Hippo signaling pathway-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Bifidobacterium	FGF basic	Bifidobacterium+Adherens junction-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-DS
Ruminococcus	FGF basic	Ruminococcus-n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-DS
Ruminococcus	FGF basic	Ruminococcus-18:3n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-DS
GCDCA+blood	FGF basic	GCDCA+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.31	0.65	no	no	no	no	no	no	DM-DS
ACA+blood	FGF basic	ACA+blood+EPA+blood+n3+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.338	0.65	no	no	no	no	no	no	DM-DS
ACA+blood	FGF basic	ACA+blood-decanoic acid C10+blood-n3+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.338	0.65	no	no	no	no	no	no	DM-DS
DCA+stool	FGF basic	DCA+stool+HDCA+stool+L-2-Aminobutyric acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.195	0.65	no	no	no	no	no	no	DM-DS
DCA+stool	FGF basic	DCA+stool+iso-LCA+stool-TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.195	0.65	no	no	no	no	no	no	DM-DS
DCA+stool	FGF basic	DCA+stool-GCA+stool+GCDCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.195	0.65	no	no	no	no	no	no	DM-DS
DCA+stool	FGF basic	DCA+stool+iso-LCA+stool-TCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.195	0.65	no	no	no	no	no	no	DM-DS
Butyric acid+stool	FGF basic	Butyric acid+stool-16:0/20:5-PC+blood+n3+blood-FGF basic	Indirect	stool_scfa	serum_cytokines	0.102	0.65	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	FGF basic	Butyric acid+stool+L-Histidine+blood-n3+blood-FGF basic	Indirect	stool_scfa	serum_cytokines	0.102	0.65	dn	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	FGF basic	4-hydroxybenzoic acid+stool-iso-LCA+stool-TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.65	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	FGF basic	4-hydroxybenzoic acid+stool-iso-LCA+stool-TCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.65	no	dn	no	no	no	no	DM-DS
Turicibacter	FGF basic	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.269	0.65	no	no	no	no	no	no	DM-DS
Turicibacter	FGF basic	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.269	0.65	no	no	no	no	no	no	DM-DS
Turicibacter	FGF basic	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.269	0.65	no	no	no	no	no	no	DM-DS
Turicibacter	FGF basic	Turicibacter+Desulfovibrio+Antigen processing and presentation+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.269	0.65	no	no	no	no	no	no	DM-DS
Turicibacter	FGF basic	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.269	0.65	no	no	no	no	no	no	DM-DS
Turicibacter	FGF basic	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.269	0.65	no	no	no	no	no	no	DM-DS
GCA+blood	FGF basic	GCA+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.16	0.65	no	no	no	no	no	no	DM-DS
ACA+stool	FGF basic	ACA+stool-L-Phenylalanine+stool-16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.417	0.65	no	no	no	no	no	no	DM-DS
ACA+stool	FGF basic	ACA+stool-L-Phenylalanine+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.417	0.65	no	no	no	no	no	no	DM-DS
CDCA+blood	FGF basic	CDCA+blood-Glycine+blood+L-Histidine+blood-n3+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.506	0.65	no	no	no	no	no	no	DM-DS
CDCA+blood	FGF basic	CDCA+blood-Ethanolamine+blood+L-Histidine+blood-n3+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.506	0.65	no	no	no	no	no	no	DM-DS
CDCA+blood	FGF basic	CDCA+blood+GCDCA+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.506	0.65	no	no	no	no	no	no	DM-DS
Prevotella	FGF basic	Prevotella+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	DM-DS
Prevotella	FGF basic	Prevotella+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	DM-DS
iso-DCA+blood	FGF basic	iso-DCA+blood+L-Citrulline+blood+L-Histidine+blood-n3+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.38	0.65	no	no	no	no	no	no	DM-DS
iso-DCA+blood	FGF basic	iso-DCA+blood+L-Asparagine+blood+L-Histidine+blood-n3+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.38	0.65	no	no	no	no	no	no	DM-DS
HCA+stool	FGF basic	HCA+stool-HDCA+stool+L-2-Aminobutyric acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.155	0.65	no	no	no	no	no	no	DM-DS
Roseburia	FGF basic	Roseburia+16:0/16:1-PC+blood-18:3n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.495	0.65	no	no	no	no	no	no	DM-DS
Roseburia	FGF basic	Roseburia+16:0/16:1-PC+blood-n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.495	0.65	no	no	no	no	no	no	DM-DS
Roseburia	FGF basic	Roseburia+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.495	0.65	no	no	no	no	no	no	DM-DS
Roseburia	FGF basic	Roseburia+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.495	0.65	no	no	no	no	no	no	DM-DS
Roseburia	FGF basic	Roseburia+16:0/16:1-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.495	0.65	no	no	no	no	no	no	DM-DS
Roseburia	FGF basic	Roseburia+GCDCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.495	0.65	no	no	no	no	no	no	DM-DS
Roseburia	FGF basic	Roseburia-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.495	0.65	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	FGF basic	12-ketoDCA+stool+GCA+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.505	0.65	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	FGF basic	12-ketoDCA+stool+HDCA+stool+L-2-Aminobutyric acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.505	0.65	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	FGF basic	12-ketoDCA+stool+iso-LCA+stool-TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.505	0.65	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	FGF basic	12-ketoDCA+stool-GCA+stool+GCDCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.505	0.65	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	FGF basic	12-ketoDCA+stool+iso-LCA+stool-TCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.505	0.65	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	FGF basic	L-Tryptophan+stool+8-HETE+blood+L-Histidine+blood-n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.557	0.65	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	FGF basic	L-Tryptophan+stool-18:3n6+blood-22:0/16:0-PE+blood+n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.557	0.65	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	FGF basic	L-Tryptophan+stool-18:3n6+blood-L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.557	0.65	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	FGF basic	L-Tryptophan+stool+8-HETE+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.557	0.65	no	no	no	no	no	no	DM-DS
CA+blood	FGF basic	CA+blood+GCDCA+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.606	0.65	no	no	no	no	no	no	DM-DS
CA+blood	FGF basic	CA+blood+GCA+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.606	0.65	no	no	no	no	no	no	DM-DS
GUDCA+stool	FGF basic	GUDCA+stool+12-HEPE+blood-DMG+blood-n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0085	0.65	no	dn	no	no	no	no	DM-DS
GUDCA+stool	FGF basic	GUDCA+stool+12-HEPE+blood+16:0/20:5-PC+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0085	0.65	no	dn	no	no	no	no	DM-DS
L-Phenylalanine+stool	FGF basic	L-Phenylalanine+stool-16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.398	0.65	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	FGF basic	L-Phenylalanine+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.398	0.65	no	no	no	no	no	no	DM-DS
GCA+stool	FGF basic	GCA+stool+GCDCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0809	0.65	no	no	no	no	no	no	DM-DS
Coprococcus	FGF basic	Coprococcus+Roseburia+GCDCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	DM-DS
Coprococcus	FGF basic	Coprococcus+Roseburia+16:0/16:1-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	DM-DS
Coprococcus	FGF basic	Coprococcus+Roseburia-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	DM-DS
Coprococcus	FGF basic	Coprococcus+16:0/16:0-PC+blood+18:0/18:2-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	DM-DS
Coprococcus	FGF basic	Coprococcus+16:0/16:0-PC+blood+18:1/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	DM-DS
Coprococcus	FGF basic	Coprococcus+Roseburia+16:0/16:1-PC+blood-18:3n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	DM-DS
Coprococcus	FGF basic	Coprococcus+16:0/16:0-PC+blood-18:0-LPC+blood-18:3n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	DM-DS
Coprococcus	FGF basic	Coprococcus+Roseburia+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	DM-DS
Coprococcus	FGF basic	Coprococcus+Roseburia+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	DM-DS
Coprococcus	FGF basic	Coprococcus+16:0/16:0-PC+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	DM-DS
Coprococcus	FGF basic	Coprococcus+16:0/16:0-PC+blood+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	DM-DS
Coprococcus	FGF basic	Coprococcus+Roseburia+16:0/16:1-PC+blood-n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	DM-DS
Coprococcus	FGF basic	Coprococcus+16:0/16:0-PC+blood+22:0/16:0-PE+blood+n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Calcium signaling pathway-18:3n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Calcium signaling pathway-16:1/16:1-PC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+JAK-STAT signaling pathway+Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Ribosome-Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vascular smooth muscle contraction-Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Oxidative phosphorylation-Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Autophagy - animal+Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+NF-kappa B signaling pathway+Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Cardiac muscle contraction-Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+FoxO signaling pathway+Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Focal adhesion-Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+JAK-STAT signaling pathway+Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Autophagy - animal+Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+NF-kappa B signaling pathway+Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Focal adhesion-Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+JAK-STAT signaling pathway+Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vibrio cholerae infection-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Dopaminergic synapse-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Morphine addiction-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Renin secretion-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vasopressin-regulated water reabsorption-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Melanogenesis-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Inflammatory mediator regulation of TRP channels-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Salivary secretion-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vascular smooth muscle contraction-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+T cell receptor signaling pathway+Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Platelet activation-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Gastric acid secretion-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Autophagy - animal+Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Circadian entrainment-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+NF-kappa B signaling pathway+Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Pancreatic secretion-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Focal adhesion-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Calcium signaling pathway-n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Shigellosis-n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+MAPK signaling pathway+n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+JAK-STAT signaling pathway+Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vascular smooth muscle contraction-Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+T cell receptor signaling pathway+Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Platelet activation-Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Autophagy - animal+Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Circadian entrainment-Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+NF-kappa B signaling pathway+Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Focal adhesion-Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Thermogenesis+Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Dopaminergic synapse+Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Inflammatory mediator regulation of TRP channels+Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vascular smooth muscle contraction+Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+T cell receptor signaling pathway-Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Autophagy - animal-Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Circadian entrainment+Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+NF-kappa B signaling pathway-Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Focal adhesion+Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Ribosome-Apoptosis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Oxidative phosphorylation-Apoptosis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Autophagy - animal+Apoptosis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+NF-kappa B signaling pathway+Apoptosis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+NF-kappa B signaling pathway+Sphingolipid signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Autophagy - animal+Cytosolic DNA-sensing pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+NF-kappa B signaling pathway+Cytosolic DNA-sensing pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Focal adhesion-Cytosolic DNA-sensing pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Thermogenesis-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+JAK-STAT signaling pathway+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Ribosome-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Prion disease-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Huntington disease-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Alzheimer disease-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Coronavirus disease - COVID-19-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Retrograde endocannabinoid signaling-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Renin secretion-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Hepatitis B+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Melanogenesis-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Inflammatory mediator regulation of TRP channels-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vascular smooth muscle contraction-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Oxidative phosphorylation-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Gastric acid secretion-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Autophagy - animal+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Non-alcoholic fatty liver disease-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Circadian entrainment-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+NF-kappa B signaling pathway+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Pathways of neurodegeneration - multiple diseases-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Cardiac muscle contraction-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Parkinson disease-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Focal adhesion-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Thermogenesis-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+JAK-STAT signaling pathway+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Ribosome-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Prion disease-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Huntington disease-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Alzheimer disease-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Retrograde endocannabinoid signaling-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Renin secretion-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Melanogenesis-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Inflammatory mediator regulation of TRP channels-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Oxidative phosphorylation-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Autophagy - animal+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Non-alcoholic fatty liver disease-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+NF-kappa B signaling pathway+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Pathways of neurodegeneration - multiple diseases-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Cardiac muscle contraction-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Parkinson disease-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Thermogenesis-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+JAK-STAT signaling pathway+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vibrio cholerae infection-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Prion disease-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Dopaminergic synapse-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Retrograde endocannabinoid signaling-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Renin secretion-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Hepatitis B+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vasopressin-regulated water reabsorption-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Melanogenesis-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Inflammatory mediator regulation of TRP channels-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Salivary secretion-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vascular smooth muscle contraction-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+T cell receptor signaling pathway+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Platelet activation-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Oxidative phosphorylation-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Gastric acid secretion-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Autophagy - animal+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Circadian entrainment-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+NF-kappa B signaling pathway+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Focal adhesion-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Thermogenesis-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+JAK-STAT signaling pathway+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vibrio cholerae infection-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Ribosome-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Prion disease-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Huntington disease-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Alzheimer disease-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Dopaminergic synapse-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Coronavirus disease - COVID-19-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Retrograde endocannabinoid signaling-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Renin secretion-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Hepatitis B+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Rap1 signaling pathway-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vasopressin-regulated water reabsorption-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Melanogenesis-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Inflammatory mediator regulation of TRP channels-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Salivary secretion-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vascular smooth muscle contraction-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+T cell receptor signaling pathway+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Platelet activation-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Oxidative phosphorylation-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Gastric acid secretion-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Autophagy - animal+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Non-alcoholic fatty liver disease-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Circadian entrainment-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+NF-kappa B signaling pathway+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Pathways of neurodegeneration - multiple diseases-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Cardiac muscle contraction-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+FoxO signaling pathway+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Parkinson disease-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Focal adhesion-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+JAK-STAT signaling pathway+B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Ribosome-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vascular smooth muscle contraction-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+T cell receptor signaling pathway+B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Oxidative phosphorylation-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Autophagy - animal+B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+NF-kappa B signaling pathway+B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Cardiac muscle contraction-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Focal adhesion-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+JAK-STAT signaling pathway+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vibrio cholerae infection-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Dopaminergic synapse-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Retrograde endocannabinoid signaling-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Renin secretion-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Hepatitis B+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Inflammatory mediator regulation of TRP channels-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Salivary secretion-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vascular smooth muscle contraction-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+T cell receptor signaling pathway+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Platelet activation-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Gastric acid secretion-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Autophagy - animal+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Circadian entrainment-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+NF-kappa B signaling pathway+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Focal adhesion-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Thermogenesis-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+JAK-STAT signaling pathway+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vibrio cholerae infection-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Ribosome-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Prion disease-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Huntington disease-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Alzheimer disease-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Dopaminergic synapse-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Retrograde endocannabinoid signaling-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Renin secretion-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Melanogenesis-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Inflammatory mediator regulation of TRP channels-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Vascular smooth muscle contraction-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+T cell receptor signaling pathway+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Platelet activation-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Oxidative phosphorylation-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Gastric acid secretion-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Autophagy - animal+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Circadian entrainment-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+NF-kappa B signaling pathway+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Cardiac muscle contraction-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+FoxO signaling pathway+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Focal adhesion-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Platinum drug resistance+Ribosome biogenesis in eukaryotes-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Platinum drug resistance+Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Progesterone-mediated oocyte maturation+Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Human cytomegalovirus infection-Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Rap1 signaling pathway-Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Spliceosome+Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+MAPK signaling pathway+Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+Progesterone-mediated oocyte maturation-18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira-Human cytomegalovirus infection+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
Oscillospira	FGF basic	Oscillospira+MAPK signaling pathway-18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-DS
iso-LCA+stool	FGF basic	iso-LCA+stool-TCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.72	0.65	no	no	no	no	no	no	DM-DS
iso-LCA+stool	FGF basic	iso-LCA+stool-TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.72	0.65	no	no	no	no	no	no	DM-DS
DCA+blood	FGF basic	DCA+blood+L-Histidine+blood-n3+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.122	0.65	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	FGF basic	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-DMG+blood-n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.33	0.65	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	FGF basic	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood+16:0/20:5-PC+blood+n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.33	0.65	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	FGF basic	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.304	0.65	no	no	no	no	no	no	DM-DS
TCA+stool	FGF basic	TCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.458	0.65	no	no	no	no	no	no	DM-DS
TCA+stool	FGF basic	TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.458	0.65	no	no	no	no	no	no	DM-DS
HDCA+stool	FGF basic	HDCA+stool+L-2-Aminobutyric acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	DM-DS
Lachnospira	FGF basic	Lachnospira-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-DS
Lachnospira	FGF basic	Lachnospira-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-DS
Lachnospira	FGF basic	Lachnospira-Cytosolic DNA-sensing pathway+FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-DS
Lachnospira	FGF basic	Lachnospira-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-DS
Fusobacterium	FGF basic	Fusobacterium-18:0/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.628	0.65	no	no	no	no	no	no	DM-DS
Fusobacterium	FGF basic	Fusobacterium+16:0-LPC+blood-18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.628	0.65	no	no	no	no	no	no	DM-DS
Fusobacterium	FGF basic	Fusobacterium-16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.628	0.65	no	no	no	no	no	no	DM-DS
Fusobacterium	FGF basic	Fusobacterium-18:0/18:2-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.628	0.65	no	no	no	no	no	no	DM-DS
Fusobacterium	FGF basic	Fusobacterium-18:0/18:1-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.628	0.65	no	no	no	no	no	no	DM-DS
Fusobacterium	FGF basic	Fusobacterium-18:1/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.628	0.65	no	no	no	no	no	no	DM-DS
Fusobacterium	FGF basic	Fusobacterium-18:0/18:0-PC+blood-18:3n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.628	0.65	no	no	no	no	no	no	DM-DS
Fusobacterium	FGF basic	Fusobacterium-18:0/18:1-PC+blood-18:3n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.628	0.65	no	no	no	no	no	no	DM-DS
GCDCA+stool	FGF basic	GCDCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-nutriCA+stool+18:1/20:3-PC+blood-n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:1-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-nutriCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:1-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:2-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-nutriCA+stool+18:1/20:3-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:0-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Proteasome-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Glycolysis / Gluconeogenesis-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Glutamatergic synapse+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	"Odoribacter-Growth hormone synthesis, secretion and action+Acute myeloid leukemia+FGF basic"	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Ferroptosis+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Fc gamma R-mediated phagocytosis+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Proteasome-Apoptosis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Glycolysis / Gluconeogenesis-Apoptosis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Neuroactive ligand-receptor interaction+Apoptosis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Antigen processing and presentation+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Proteasome-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Glycolysis / Gluconeogenesis-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Neuroactive ligand-receptor interaction+B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Proteasome-cAMP signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Glycolysis / Gluconeogenesis-cAMP signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Proteasome-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Glycolysis / Gluconeogenesis-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Glutamatergic synapse+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	"Odoribacter-Growth hormone synthesis, secretion and action+Chagas disease+FGF basic"	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Long-term depression+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Ferroptosis+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Proteasome-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Glycolysis / Gluconeogenesis-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	"Odoribacter-Growth hormone synthesis, secretion and action+Chronic myeloid leukemia+FGF basic"	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Longevity regulating pathway - multiple species-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Proteasome+Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Fc gamma R-mediated phagocytosis-Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Morphine addiction-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Proteasome-Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Glycolysis / Gluconeogenesis-Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Neuroactive ligand-receptor interaction+Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Pathogenic Escherichia coli infection-Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Necroptosis-Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Long-term depression-Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Ferroptosis-Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Longevity regulating pathway - multiple species+Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Endocrine resistance-Sphingolipid signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Proteasome-Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Glycolysis / Gluconeogenesis-Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Necroptosis-n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Serotonergic synapse+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Proteasome-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Glycolysis / Gluconeogenesis-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Glutamatergic synapse+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	"Odoribacter-Growth hormone synthesis, secretion and action+Amoebiasis+FGF basic"	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Neuroactive ligand-receptor interaction+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Leishmaniasis-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Gap junction+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Legionellosis-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Long-term depression+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Ferroptosis+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Fc gamma R-mediated phagocytosis+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Proteasome-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Glycolysis / Gluconeogenesis-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Proteasome-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Glycolysis / Gluconeogenesis-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	"Odoribacter-Growth hormone synthesis, secretion and action+Small cell lung cancer+FGF basic"	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Serotonergic synapse+Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Proteasome-Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Glycolysis / Gluconeogenesis-Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Glutamatergic synapse+Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Gap junction+Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Necroptosis+Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Long-term depression+Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Carbon metabolism-Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter-Ferroptosis+Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Odoribacter	FGF basic	Odoribacter+Longevity regulating pathway - multiple species-Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-DS
Actinomyces	FGF basic	Actinomyces+Coprococcus+Roseburia+GCDCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.621	0.65	no	no	no	no	no	no	DM-DS
Actinomyces	FGF basic	Actinomyces+Coprococcus+Roseburia+16:0/16:1-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.621	0.65	no	no	no	no	no	no	DM-DS
Actinomyces	FGF basic	Actinomyces+Coprococcus+Roseburia-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.621	0.65	no	no	no	no	no	no	DM-DS
Actinomyces	FGF basic	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:0/18:2-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.621	0.65	no	no	no	no	no	no	DM-DS
Actinomyces	FGF basic	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:1/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.621	0.65	no	no	no	no	no	no	DM-DS
Actinomyces	FGF basic	Actinomyces+Coprococcus+Roseburia+16:0/16:1-PC+blood-18:3n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.621	0.65	no	no	no	no	no	no	DM-DS
Actinomyces	FGF basic	Actinomyces+Coprococcus+16:0/16:0-PC+blood-18:0-LPC+blood-18:3n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.621	0.65	no	no	no	no	no	no	DM-DS
Actinomyces	FGF basic	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.621	0.65	no	no	no	no	no	no	DM-DS
Actinomyces	FGF basic	Actinomyces+Coprococcus+Roseburia+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.621	0.65	no	no	no	no	no	no	DM-DS
Actinomyces	FGF basic	Actinomyces+Coprococcus+16:0/16:0-PC+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.621	0.65	no	no	no	no	no	no	DM-DS
Actinomyces	FGF basic	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.621	0.65	no	no	no	no	no	no	DM-DS
Actinomyces	FGF basic	Actinomyces+Coprococcus+Roseburia+16:0/16:1-PC+blood-n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.621	0.65	no	no	no	no	no	no	DM-DS
Actinomyces	FGF basic	Actinomyces+Coprococcus+16:0/16:0-PC+blood+22:0/16:0-PE+blood+n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.621	0.65	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	FGF basic	Isobutyric acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic	Indirect	stool_scfa	serum_cytokines	0.408	0.65	no	no	no	no	no	no	DM-DS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-nutriCA+stool+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-nutriCA+stool+18:1/20:3-PC+blood-n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool+L-Phenylalanine+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-nutriCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool+L-Phenylalanine+stool-16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-nutriCA+stool+18:0/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-nutriCA+stool+18:0/18:1-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-nutriCA+stool+18:0/18:0-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-nutriCA+stool+18:1/20:3-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-nutriCA+stool+18:0/20:2-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-nutriCA+stool+18:0/18:1-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-DS
Caproic acid+stool	FGF basic	Caproic acid+stool-TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_scfa	serum_cytokines	0.882	0.65	no	no	no	no	no	no	DM-DS
Caproic acid+stool	FGF basic	Caproic acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic	Indirect	stool_scfa	serum_cytokines	0.882	0.65	no	no	no	no	no	no	DM-DS
Caproic acid+stool	FGF basic	Caproic acid+stool-TCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	stool_scfa	serum_cytokines	0.882	0.65	no	no	no	no	no	no	DM-DS
Eggerthella	FGF basic	Eggerthella-Yersinia infection+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.912	0.65	no	no	no	no	no	no	DM-DS
Eggerthella	FGF basic	Eggerthella+Phosphatidylinositol signaling system-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.912	0.65	no	no	no	no	no	no	DM-DS
Eggerthella	FGF basic	Eggerthella-Yersinia infection-Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.912	0.65	no	no	no	no	no	no	DM-DS
Eggerthella	FGF basic	Eggerthella+Phosphatidylinositol signaling system+Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.912	0.65	no	no	no	no	no	no	DM-DS
Eggerthella	FGF basic	Eggerthella-Influenza A-Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.912	0.65	no	no	no	no	no	no	DM-DS
Eggerthella	FGF basic	Eggerthella+AMPK signaling pathway-Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.912	0.65	no	no	no	no	no	no	DM-DS
Eggerthella	FGF basic	Eggerthella+Phosphatidylinositol signaling system-Cytosolic DNA-sensing pathway+FGF basic	Indirect	Genus	serum_cytokines	0.912	0.65	no	no	no	no	no	no	DM-DS
Eggerthella	FGF basic	Eggerthella+Phosphatidylinositol signaling system+Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.912	0.65	no	no	no	no	no	no	DM-DS
Eggerthella	FGF basic	Eggerthella+Phosphatidylinositol signaling system-Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.912	0.65	no	no	no	no	no	no	DM-DS
Eggerthella	FGF basic	Eggerthella+Phosphatidylinositol signaling system-Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.912	0.65	no	no	no	no	no	no	DM-DS
Eggerthella	FGF basic	Eggerthella+AMPK signaling pathway-Apoptosis+FGF basic	Indirect	Genus	serum_cytokines	0.912	0.65	no	no	no	no	no	no	DM-DS
Eggerthella	FGF basic	Eggerthella+Phosphatidylinositol signaling system-Apoptosis+FGF basic	Indirect	Genus	serum_cytokines	0.912	0.65	no	no	no	no	no	no	DM-DS
Eggerthella	FGF basic	Eggerthella+AMPK signaling pathway-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.912	0.65	no	no	no	no	no	no	DM-DS
Eggerthella	FGF basic	Eggerthella+Phosphatidylinositol signaling system-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.912	0.65	no	no	no	no	no	no	DM-DS
Anaerotruncus	FGF basic	Anaerotruncus-Ruminococcus-n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.904	0.65	no	no	no	no	no	no	DM-DS
Anaerotruncus	FGF basic	Anaerotruncus-Ruminococcus-18:3n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.904	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes-Oxytocin signaling pathway-Hepatitis C+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes-Alcoholism+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes-Neutrophil extracellular trap formation+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes+RNA degradation-Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes-Oxytocin signaling pathway-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes-Rap1 signaling pathway-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes-Neutrophil extracellular trap formation+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes+RNA degradation-Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes-Oxytocin signaling pathway-Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes+RNA degradation-Apoptosis+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes+Spliceosome+Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes-Rap1 signaling pathway-Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes-Neutrophil extracellular trap formation+B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes+RNA degradation-B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes+L-2-Aminobutyric acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes-Neutrophil extracellular trap formation+Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes+RNA degradation-Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes-Oxytocin signaling pathway-Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes+RNA degradation-Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes-Neutrophil extracellular trap formation-Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
Anaerostipes	FGF basic	Anaerostipes+RNA degradation+Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-DHA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool+9-HODE+blood+AA+blood+DHA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-d18:1-14:0-SM+blood+d18:1-14:1-SM+blood-DHA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool+9-HODE+blood-d18:1-14:1-SM+blood-DHA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-L-2-Aminobutyric acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool+9-HODE+blood+AA+blood+L-2-Aminobutyric acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-L-2-Aminobutyric acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:3/16:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:3/18:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-20:3/18:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:5/18:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-d18:1-18:0-SM+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:2-PC+blood-d18:1-18:0-SM+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-EPA+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool+9-HODE+blood+AA+blood+EPA+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-22:6n3+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-d18:1-14:0-SM+blood+d18:1-20:0-SM+blood-decanoic acid C10+blood-n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood-Creatinine+blood+DMG+blood-n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood+DMG+blood-n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood-DMG+blood-n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood+16:0/20:5-PC+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+L-Histidine+blood-n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood-DL-methionine sulfoxide+blood+L-Histidine+blood-n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-d18:1-14:0-SM+blood-Ethanolamine+blood+L-Histidine+blood-n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-d18:1-14:0-SM+blood-L-Asparagine+blood+L-Histidine+blood-n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood+18:2-LPE+blood-n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-20:5n3+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood+18:1/18:0-PS+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood+18:0/18:0-PS+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:1/20:4-PC+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:2-PC+blood-20:1/20:4-PC+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:1-PC+blood-20:1/20:4-PC+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:5/18:0-PC+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-22:0/16:0-PE+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-22:6-LPC+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:2-PC+blood+18:3-LPC+blood+18:3n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:1-PC+blood+18:3-LPC+blood+18:3n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood+18:3-LPC+blood+18:3n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood-18:0/20:3-PI+blood-18:3n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood+18:1/18:1-PG+blood-18:3n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
TUDCA+stool	FGF basic	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood-18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	FGF basic	Isovaleric acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic	Indirect	stool_scfa	serum_cytokines	0.343	0.65	no	no	no	no	no	no	DM-DS
Paraprevotella	FGF basic	Paraprevotella-Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.118	0.65	no	no	no	no	no	no	DM-DS
Paraprevotella	FGF basic	Paraprevotella+Ribosome biogenesis in eukaryotes-FGF basic	Indirect	Genus	serum_cytokines	0.118	0.65	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	FGF basic	¦Ø-MCA+stool+CDCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.919	0.65	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	FGF basic	Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.785	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+Pathways in cancer+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+ErbB signaling pathway+Chronic myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+ErbB signaling pathway+Neurotrophin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+Pathways in cancer+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+ErbB signaling pathway+Prostate cancer+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+Pathways in cancer+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+ErbB signaling pathway+Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+ErbB signaling pathway+Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+Pathways in cancer+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+ErbB signaling pathway+Acute myeloid leukemia+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+Signaling pathways regulating pluripotency of stem cells-16:1/16:1-PC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+Colorectal cancer-16:1/16:1-PC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+Gastric cancer-16:1/16:1-PC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+ErbB signaling pathway+Chagas disease+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+ErbB signaling pathway+B cell receptor signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+ErbB signaling pathway+Fc epsilon RI signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
Gemmiger	FGF basic	Gemmiger+ErbB signaling pathway-Estrogen signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-DS
GDCA+stool	FGF basic	GDCA+stool-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.656	0.65	no	no	no	no	no	no	DM-DS
GDCA+stool	FGF basic	GDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.656	0.65	no	no	no	no	no	no	DM-DS
Methanobrevibacter	FGF basic	Methanobrevibacter-Alcoholism+Amoebiasis+FGF basic	Indirect	Genus	serum_cytokines	0.629	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-nutriCA+stool+18:1/20:3-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-nutriCA+stool+18:0/18:1-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-nutriCA+stool+18:0/18:0-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-nutriCA+stool+18:0/20:2-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-nutriCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-nutriCA+stool+18:0/20:3-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-18:2/20:4-PC+blood-DMG+blood-n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-18:2/20:4-PC+blood+20:4n6+blood+n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-nutriCA+stool+18:1/20:3-PC+blood-n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-18:2/20:4-PC+blood+EPA+blood+n3+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-18:2/20:4-PC+blood+20:4n6+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-nutriCA+stool+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-18:2/20:4-PC+blood+20:3/16:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-nutriCA+stool+18:0/18:1-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-nutriCA+stool+18:0/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-nutriCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-nutriCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-nutriCA+stool+18:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-DS
CDCA+stool	FGF basic	CDCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.663	0.65	no	no	no	no	no	no	DM-DS
CA+stool	FGF basic	CA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.827	0.65	no	no	no	no	no	no	DM-DS
CA+stool	FGF basic	CA+stool+CDCA+stool+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.827	0.65	no	no	no	no	no	no	DM-DS
HDCA+blood	FGF basic	HDCA+blood+Hypotaurine+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.483	0.65	no	no	no	no	no	no	DM-DS
HDCA+blood	FGF basic	HDCA+blood+Hypotaurine+blood+L-Histidine+blood-n3+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.483	0.65	no	no	no	no	no	no	DM-DS
UDCA+stool	FGF basic	UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.266	0.65	no	no	no	no	no	no	DM-DS
UDCA+stool	FGF basic	UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.266	0.65	no	no	no	no	no	no	DM-DS
UDCA+stool	FGF basic	UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.266	0.65	no	no	no	no	no	no	DM-DS
TDCA+stool	FGF basic	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.963	0.65	no	no	no	no	no	no	DM-DS
TDCA+stool	FGF basic	TDCA+stool-12-ketoDCA+blood-18:0/22:6-PI+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.963	0.65	no	no	no	no	no	no	DM-DS
TDCA+stool	FGF basic	TDCA+stool-12-ketoDCA+blood-18:0/22:6-PE+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.963	0.65	no	no	no	no	no	no	DM-DS
TDCA+stool	FGF basic	TDCA+stool-12-ketoDCA+blood-18:1/22:6-PE+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.963	0.65	no	no	no	no	no	no	DM-DS
TDCA+stool	FGF basic	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood+n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.963	0.65	no	no	no	no	no	no	DM-DS
TDCA+stool	FGF basic	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PE+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.963	0.65	no	no	no	no	no	no	DM-DS
TDCA+stool	FGF basic	TDCA+stool-12-ketoDCA+blood-16:1/18:1-PG+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.963	0.65	no	no	no	no	no	no	DM-DS
TDCA+stool	FGF basic	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PI+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.963	0.65	no	no	no	no	no	no	DM-DS
TDCA+stool	FGF basic	TDCA+stool-12-ketoDCA+blood-18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.963	0.65	no	no	no	no	no	no	DM-DS
TDCA+stool	FGF basic	TDCA+stool-12-ketoDCA+blood-18:0/20:3-PI+blood-18:3n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.963	0.65	no	no	no	no	no	no	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	FGF basic	4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Direct	urine_cometabolism	serum_cytokines	0.973	0.65	no	no	no	no	no	no	DM-DS
Desulfovibrio	FGF basic	Desulfovibrio+Human T-cell leukemia virus 1 infection+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.27	0.65	no	no	no	no	no	no	DM-DS
Desulfovibrio	FGF basic	Desulfovibrio+Human cytomegalovirus infection+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.27	0.65	no	no	no	no	no	no	DM-DS
Desulfovibrio	FGF basic	Desulfovibrio+Human immunodeficiency virus 1 infection+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.27	0.65	no	no	no	no	no	no	DM-DS
Desulfovibrio	FGF basic	Desulfovibrio+Antigen processing and presentation+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.27	0.65	no	no	no	no	no	no	DM-DS
Desulfovibrio	FGF basic	Desulfovibrio+Herpes simplex virus 1 infection+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.27	0.65	no	no	no	no	no	no	DM-DS
Desulfovibrio	FGF basic	Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.27	0.65	no	no	no	no	no	no	DM-DS
nutriCA+stool	FGF basic	nutriCA+stool+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.481	0.65	no	no	no	no	no	no	DM-DS
nutriCA+stool	FGF basic	nutriCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.481	0.65	no	no	no	no	no	no	DM-DS
nutriCA+stool	FGF basic	nutriCA+stool+18:0/18:1-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.481	0.65	no	no	no	no	no	no	DM-DS
nutriCA+stool	FGF basic	nutriCA+stool+18:0/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.481	0.65	no	no	no	no	no	no	DM-DS
nutriCA+stool	FGF basic	nutriCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.481	0.65	no	no	no	no	no	no	DM-DS
nutriCA+stool	FGF basic	nutriCA+stool+18:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.481	0.65	no	no	no	no	no	no	DM-DS
nutriCA+stool	FGF basic	nutriCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.481	0.65	no	no	no	no	no	no	DM-DS
nutriCA+stool	FGF basic	nutriCA+stool+18:0/18:1-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.481	0.65	no	no	no	no	no	no	DM-DS
nutriCA+stool	FGF basic	nutriCA+stool+18:0/18:0-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.481	0.65	no	no	no	no	no	no	DM-DS
nutriCA+stool	FGF basic	nutriCA+stool+18:1/20:3-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.481	0.65	no	no	no	no	no	no	DM-DS
nutriCA+stool	FGF basic	nutriCA+stool+18:0/20:3-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.481	0.65	no	no	no	no	no	no	DM-DS
nutriCA+stool	FGF basic	nutriCA+stool+18:0/20:2-PC+blood-18:3n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.481	0.65	no	no	no	no	no	no	DM-DS
nutriCA+stool	FGF basic	nutriCA+stool+18:1/20:3-PC+blood-n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.481	0.65	no	no	no	no	no	no	DM-DS
Bilophila	FGF basic	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.528	0.65	no	no	no	no	no	no	DM-DS
Bilophila	FGF basic	Bilophila+Desulfovibrio+Human cytomegalovirus infection+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.528	0.65	no	no	no	no	no	no	DM-DS
Bilophila	FGF basic	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.528	0.65	no	no	no	no	no	no	DM-DS
Bilophila	FGF basic	Bilophila+Desulfovibrio+Antigen processing and presentation+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.528	0.65	no	no	no	no	no	no	DM-DS
Bilophila	FGF basic	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+18:1/18:1-PC+blood+FGF basic	Indirect	Genus	serum_cytokines	0.528	0.65	no	no	no	no	no	no	DM-DS
Bilophila	FGF basic	Bilophila+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-FGF basic	Indirect	Genus	serum_cytokines	0.528	0.65	no	no	no	no	no	no	DM-DS
GDCA+blood	FGF basic	GDCA+blood+Hypotaurine+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.632	0.65	no	no	no	no	no	no	DM-DS
GDCA+blood	FGF basic	GDCA+blood+Hypotaurine+blood+L-Histidine+blood-n3+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.632	0.65	no	no	no	no	no	no	DM-DS
acetic acid C2+blood	FGF basic	acetic acid C2+blood+d18:1-20:1-SM+blood-decanoic acid C10+blood-n3+blood-FGF basic	Indirect	serum_scfa	serum_cytokines	0.000193	0.65	up	dn	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	FGF basic	isovaleric acid iso-C5+blood+n3+blood-FGF basic	Indirect	serum_scfa	serum_cytokines	0.117	0.65	no	no	no	no	no	no	DM-DS
Clostridium	FGF basic	Clostridium-Small cell lung cancer+FGF basic	Indirect	Genus	serum_cytokines	0.925	0.65	no	no	no	no	no	no	DM-DS
Clostridium	FGF basic	Clostridium-Relaxin signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.925	0.65	no	no	no	no	no	no	DM-DS
Clostridium	FGF basic	Clostridium-cAMP signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.925	0.65	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	FGF basic	T-¦Á-MCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.48	0.65	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	FGF basic	T-¦Á-MCA+stool-UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.48	0.65	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	FGF basic	T-¦Á-MCA+stool-UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.48	0.65	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	FGF basic	12-ketoDCA+blood-18:0/20:3-PI+blood-18:3n3+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.517	0.65	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	FGF basic	12-ketoDCA+blood-18:0/18:1-PI+blood+18:1/18:1-PC+blood+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.517	0.65	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	FGF basic	12-ketoDCA+blood-16:1/18:1-PG+blood+18:1/18:1-PC+blood+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.517	0.65	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	FGF basic	12-ketoDCA+blood-18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.517	0.65	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	FGF basic	12-ketoDCA+blood-18:0/18:1-PE+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.517	0.65	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	FGF basic	12-ketoDCA+blood-18:0/18:0-PS+blood+n3+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.517	0.65	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	FGF basic	12-ketoDCA+blood-18:1/22:6-PE+blood+n3+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.517	0.65	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	FGF basic	12-ketoDCA+blood-18:0/22:6-PI+blood+n3+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.517	0.65	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	FGF basic	12-ketoDCA+blood-16:0/18:0-PS+blood+n3+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.517	0.65	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	FGF basic	12-ketoDCA+blood-18:0/22:6-PE+blood+n3+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.517	0.65	no	no	no	no	no	no	DM-DS
Butyricicoccus	FGF basic	Butyricicoccus-18:2/20:4-PC+blood-DMG+blood-n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-DS
Butyricicoccus	FGF basic	Butyricicoccus-18:2/20:4-PC+blood+20:4n6+blood+n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-DS
Butyricicoccus	FGF basic	Butyricicoccus-18:2/20:4-PC+blood+EPA+blood+n3+blood-FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-DS
Butyricicoccus	FGF basic	"Butyricicoccus+12,13-EPOME+blood-18:0/20:4-PI+blood+n3+blood-FGF basic"	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-DS
Butyricicoccus	FGF basic	Butyricicoccus-18:2/20:4-PC+blood+20:4n6+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-DS
Butyricicoccus	FGF basic	Butyricicoccus-18:2/20:4-PC+blood+20:3/16:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-DS
Butyricicoccus	FGF basic	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic"	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-DS
Butyricicoccus	FGF basic	"Butyricicoccus+12,13-EPOME+blood+18:0/18:1-PE+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic"	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-DS
Blautia	GIP	Blautia+L-Tryptophan+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	1.36E-05	0.374	up	dn	dn	no	no	no	DM-DS
Blautia	GIP	Blautia+L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	1.36E-05	0.374	up	dn	dn	no	no	no	DM-DS
Blautia	GIP	Blautia+CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	1.36E-05	0.374	up	dn	dn	no	no	no	DM-DS
Blautia	GIP	Blautia+L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	1.36E-05	0.374	up	dn	dn	no	no	no	DM-DS
Parabacteroides	GIP	Parabacteroides-C-peptide-GIP	Indirect	Genus	DM-associated hormones	4.19E-05	0.374	no	up	up	no	no	no	DM-DS
Dorea	GIP	Dorea+L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.00362	0.374	up	no	dn	no	no	no	DM-DS
Dorea	GIP	Dorea+GCDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.00362	0.374	up	no	dn	no	no	no	DM-DS
Dorea	GIP	Dorea+L-Tryptophan+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.00362	0.374	up	no	dn	no	no	no	DM-DS
Dorea	GIP	Dorea+L-Proline+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.00362	0.374	up	no	dn	no	no	no	DM-DS
Dorea	GIP	Dorea+CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.00362	0.374	up	no	dn	no	no	no	DM-DS
Dorea	GIP	Dorea+L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.00362	0.374	up	no	dn	no	no	no	DM-DS
Faecalibacterium	GIP	Faecalibacterium-Phenylacetic acid+stool-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.0039	0.374	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	GIP	Faecalibacterium+GCDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.0039	0.374	no	dn	dn	no	no	no	DM-DS
TUDCA+blood	GIP	TUDCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.374	no	no	dn	no	no	no	DM-DS
Bacteroides	GIP	Bacteroides-n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.000267	0.374	dn	dn	up	no	no	no	DM-DS
Bacteroides	GIP	Bacteroides-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.000267	0.374	dn	dn	up	no	no	no	DM-DS
Bacteroides	GIP	Bacteroides+Parabacteroides-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.000267	0.374	dn	dn	up	no	no	no	DM-DS
Bacteroides	GIP	Bacteroides+16:0/22:6-PC+blood-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.000267	0.374	dn	dn	up	no	no	no	DM-DS
Bacteroides	GIP	Bacteroides+16:0/20:5-PC+blood-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.000267	0.374	dn	dn	up	no	no	no	DM-DS
Bacteroides	GIP	Bacteroides+Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.000267	0.374	dn	dn	up	no	no	no	DM-DS
Propionic acid+stool	GIP	Propionic acid+stool-L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_scfa	DM-associated hormones	0.0436	0.374	dn	no	up	no	no	no	DM-DS
[Ruminococcus]	GIP	[Ruminococcus]+L-Proline+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.0679	0.374	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	GIP	[Ruminococcus]+L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.0679	0.374	no	no	dn	no	no	no	DM-DS
GUDCA+blood	GIP	GUDCA+blood+TUDCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.374	no	no	dn	no	no	no	DM-DS
GUDCA+blood	GIP	GUDCA+blood+HCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.374	no	no	dn	no	no	no	DM-DS
GUDCA+blood	GIP	GUDCA+blood+UDCA+blood+Eotaxin-IL-6-IP-10+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.374	no	no	dn	no	no	no	DM-DS
UDCA+blood	GIP	UDCA+blood+Eotaxin-IL-6-IP-10+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.0939	0.374	no	no	dn	no	no	no	DM-DS
Acetic acid+stool	GIP	Acetic acid+stool-16:0/18:0-PS+blood-n6/n3+blood+C-peptide-GIP	Indirect	stool_scfa	DM-associated hormones	0.0656	0.374	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	GIP	Acetic acid+stool-18:0/18:0-PS+blood-n6/n3+blood+C-peptide-GIP	Indirect	stool_scfa	DM-associated hormones	0.0656	0.374	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	GIP	Acetic acid+stool+L-Histidine+blood+n6/n3+blood+C-peptide-GIP	Indirect	stool_scfa	DM-associated hormones	0.0656	0.374	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	GIP	Acetic acid+stool-16:0/18:0-PS+blood+16:0/20:5-PC+blood-C-peptide-GIP	Indirect	stool_scfa	DM-associated hormones	0.0656	0.374	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	GIP	Acetic acid+stool+Butyric acid+stool-16:0/20:5-PC+blood-C-peptide-GIP	Indirect	stool_scfa	DM-associated hormones	0.0656	0.374	dn	no	no	no	no	no	DM-DS
Alistipes	GIP	Alistipes-L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.0114	0.374	no	up	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas-Creatinine+blood+L-Tryptophan+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas-L-Glutamine+blood+L-Tryptophan+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas+Cholinergic synapse-L-Tryptophan+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas-L-Methionine+blood+L-Tryptophan+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas-L-Isoleucine+blood+L-Tryptophan+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas+20:5n3+blood-n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas-L-Asparagine+blood+n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas+Cholinergic synapse-n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas-L-Isoleucine+blood+n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas+Cholinergic synapse+16:0/20:5-PC+blood-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas-Butyric acid+stool-16:0/20:5-PC+blood-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas+20:5n3+blood-L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas-Creatinine+blood+L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas-L-Glutamine+blood+L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas+Cholinergic synapse-L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas-L-Methionine+blood+L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas-L-Isoleucine+blood+L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas+Cholinergic synapse-L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas-L-Methionine+blood+L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas-L-Isoleucine+blood+L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Butyricimonas	GIP	Butyricimonas-iso-DCA+blood-IP-10+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.17	0.374	no	no	no	no	no	no	DM-DS
Collinsella	GIP	Collinsella+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.128	0.374	no	no	no	no	no	no	DM-DS
5-Hydroxytryptamine+urine	GIP	5-Hydroxytryptamine+urine-Hippuric acid+urine-IL-6-IP-10+C-peptide-GIP	Indirect	urine_cometabolism	DM-associated hormones	0.171	0.374	no	no	no	no	no	no	DM-DS
Sarcina	GIP	Sarcina+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.0703	0.374	no	no	no	no	no	no	DM-DS
Sarcina	GIP	Sarcina+IP-10+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.0703	0.374	no	no	no	no	no	no	DM-DS
Sarcina	GIP	Sarcina+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.0703	0.374	no	no	no	no	no	no	DM-DS
Methanosphaera	GIP	Methanosphaera-Roseburia+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.0703	0.374	no	no	no	no	no	no	DM-DS
iso-DCA+stool	GIP	iso-DCA+stool+Propionic acid+stool-L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.155	0.374	no	no	no	no	no	no	DM-DS
LCA+stool	GIP	LCA+stool-UDCA+stool+L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.314	0.374	no	no	no	no	no	no	DM-DS
Akkermansia	GIP	Akkermansia-Cholinergic synapse+16:0/20:5-PC+blood-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.23	0.374	no	no	no	no	no	no	DM-DS
Akkermansia	GIP	Akkermansia-Cholinergic synapse-L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.23	0.374	no	no	no	no	no	no	DM-DS
Akkermansia	GIP	Akkermansia-Cholinergic synapse-L-Tryptophan+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.23	0.374	no	no	no	no	no	no	DM-DS
Akkermansia	GIP	Akkermansia-Cholinergic synapse-L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.23	0.374	no	no	no	no	no	no	DM-DS
Akkermansia	GIP	Akkermansia-Cholinergic synapse-n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.23	0.374	no	no	no	no	no	no	DM-DS
Akkermansia	GIP	Akkermansia-Longevity regulating pathway-CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.23	0.374	no	no	no	no	no	no	DM-DS
Bifidobacterium	GIP	Bifidobacterium+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.105	0.374	no	dn	no	no	no	no	DM-DS
3-Hydroxytyramine hydrochloride+urine	GIP	3-Hydroxytyramine hydrochloride+urine-Hippuric acid+urine-IL-6-IP-10+C-peptide-GIP	Indirect	urine_cometabolism	DM-associated hormones	0.288	0.374	no	no	no	no	no	no	DM-DS
Ruminococcus	GIP	Ruminococcus+L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.335	0.374	no	no	no	no	no	no	DM-DS
Ruminococcus	GIP	Ruminococcus+IP-10+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.335	0.374	no	no	no	no	no	no	DM-DS
GCDCA+blood	GIP	GCDCA+blood+L-Tyrosine+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.31	0.374	no	no	no	no	no	no	DM-DS
GCDCA+blood	GIP	GCDCA+blood+L-Proline+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.31	0.374	no	no	no	no	no	no	DM-DS
ACA+blood	GIP	ACA+blood-decanoic acid C10+blood+L-Phenylalanine+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.338	0.374	no	no	no	no	no	no	DM-DS
ACA+blood	GIP	ACA+blood+EPA+blood-n6/n3+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.338	0.374	no	no	no	no	no	no	DM-DS
ACA+blood	GIP	ACA+blood-decanoic acid C10+blood+n6/n3+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.338	0.374	no	no	no	no	no	no	DM-DS
DCA+stool	GIP	DCA+stool-GCA+stool+GCDCA+stool+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.195	0.374	no	no	no	no	no	no	DM-DS
DCA+stool	GIP	DCA+stool-GCA+stool+L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.195	0.374	no	no	no	no	no	no	DM-DS
Hippuric acid+urine	GIP	Hippuric acid+urine-IL-6-IP-10+C-peptide-GIP	Indirect	urine_cometabolism	DM-associated hormones	0.361	0.374	no	no	no	no	no	no	DM-DS
Butyric acid+stool	GIP	Butyric acid+stool-16:0/20:5-PC+blood-C-peptide-GIP	Indirect	stool_scfa	DM-associated hormones	0.102	0.374	dn	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	GIP	4-hydroxybenzoic acid+stool-DCA+stool-GCA+stool+L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.374	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	GIP	4-hydroxybenzoic acid+stool-LCA+stool-UDCA+stool+L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.374	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	GIP	4-hydroxybenzoic acid+stool-iso-LCA+stool-UDCA+stool+L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.374	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	GIP	4-hydroxybenzoic acid+stool-iso-LCA+stool-TCA+stool-16:0/22:6-PC+blood-C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.374	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	GIP	4-hydroxybenzoic acid+stool-iso-LCA+stool-TCA+stool+L-Proline+blood+C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.374	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	GIP	4-hydroxybenzoic acid+stool-DCA+stool-GCA+stool+GCDCA+stool+C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.374	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	GIP	4-hydroxybenzoic acid+stool+L-Tryptophan+stool+Homovanillic acid+urine-IP-10+C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.374	no	dn	no	no	no	no	DM-DS
Turicibacter	GIP	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.269	0.374	no	no	no	no	no	no	DM-DS
Turicibacter	GIP	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.269	0.374	no	no	no	no	no	no	DM-DS
Turicibacter	GIP	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.269	0.374	no	no	no	no	no	no	DM-DS
Turicibacter	GIP	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.269	0.374	no	no	no	no	no	no	DM-DS
Turicibacter	GIP	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.269	0.374	no	no	no	no	no	no	DM-DS
Turicibacter	GIP	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.269	0.374	no	no	no	no	no	no	DM-DS
Turicibacter	GIP	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.269	0.374	no	no	no	no	no	no	DM-DS
GCA+blood	GIP	GCA+blood+L-Proline+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.16	0.374	no	no	no	no	no	no	DM-DS
ACA+stool	GIP	ACA+stool-L-Phenylalanine+stool+Phenylacetic acid+stool-C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.417	0.374	no	no	no	no	no	no	DM-DS
CDCA+blood	GIP	CDCA+blood+GCDCA+blood+L-Proline+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.506	0.374	no	no	no	no	no	no	DM-DS
CDCA+blood	GIP	CDCA+blood-Ethanolamine+blood+n6/n3+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.506	0.374	no	no	no	no	no	no	DM-DS
CDCA+blood	GIP	CDCA+blood+GCDCA+blood+L-Tyrosine+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.506	0.374	no	no	no	no	no	no	DM-DS
capric acid C6+blood	GIP	capric acid C6+blood-HCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide-GIP	Indirect	serum_scfa	DM-associated hormones	0.433	0.374	no	no	no	no	no	no	DM-DS
Prevotella	GIP	Prevotella+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.287	0.374	no	no	no	no	no	no	DM-DS
TCA+blood	GIP	TCA+blood+TUDCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.339	0.374	no	no	no	no	no	no	DM-DS
iso-DCA+blood	GIP	iso-DCA+blood-IP-10+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.38	0.374	no	no	no	no	no	no	DM-DS
HCA+stool	GIP	HCA+stool-HDCA+stool+L-2-Aminobutyric acid+blood-L-Proline+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.155	0.374	no	no	no	no	no	no	DM-DS
Roseburia	GIP	Roseburia+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.495	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	GIP	12-ketoDCA+stool+GCA+blood+L-Proline+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.505	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	GIP	12-ketoDCA+stool-GCA+stool+GCDCA+stool+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.505	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	GIP	12-ketoDCA+stool-GCA+stool+L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.505	0.374	no	no	no	no	no	no	DM-DS
GLCA+blood	GIP	GLCA+blood+TDCA+blood-IP-10+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.319	0.374	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	GIP	L-Tryptophan+stool+Homovanillic acid+urine-IP-10+C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.374	no	no	no	no	no	no	DM-DS
CA+blood	GIP	CA+blood+GCDCA+blood+L-Tyrosine+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.606	0.374	no	no	no	no	no	no	DM-DS
CA+blood	GIP	CA+blood+GCDCA+blood+L-Proline+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.606	0.374	no	no	no	no	no	no	DM-DS
CA+blood	GIP	CA+blood+GCA+blood+L-Proline+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.606	0.374	no	no	no	no	no	no	DM-DS
CA+blood	GIP	CA+blood+TDCA+blood-IP-10+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.606	0.374	no	no	no	no	no	no	DM-DS
GUDCA+stool	GIP	GUDCA+stool+12-HEPE+blood-L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.374	no	dn	no	no	no	no	DM-DS
GUDCA+stool	GIP	GUDCA+stool+12-HEPE+blood-L-Tryptophan+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.374	no	dn	no	no	no	no	DM-DS
GUDCA+stool	GIP	GUDCA+stool+12-HEPE+blood+16:0/20:5-PC+blood-C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.374	no	dn	no	no	no	no	DM-DS
GUDCA+stool	GIP	GUDCA+stool+12-HEPE+blood-L-Phenylalanine+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.374	no	dn	no	no	no	no	DM-DS
L-Phenylalanine+stool	GIP	L-Phenylalanine+stool+Phenylacetic acid+stool-C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.374	no	no	no	no	no	no	DM-DS
GCA+stool	GIP	GCA+stool+GCDCA+stool+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.374	no	no	no	no	no	no	DM-DS
GCA+stool	GIP	GCA+stool+L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.374	no	no	no	no	no	no	DM-DS
Coprococcus	GIP	Coprococcus+L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.612	0.374	no	no	no	no	no	no	DM-DS
Coprococcus	GIP	Coprococcus+L-Tryptophan+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.612	0.374	no	no	no	no	no	no	DM-DS
Coprococcus	GIP	Coprococcus+Roseburia+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.612	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Human cytomegalovirus infection+20:3n6+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+MAPK signaling pathway-20:3n6+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Shigellosis-16:0/22:6-PC+blood-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+MAPK signaling pathway+16:0/22:6-PC+blood-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+MAPK signaling pathway-L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Thermogenesis-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Ribosome-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Prion disease-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Huntington disease-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Alzheimer disease-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Dopaminergic synapse-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Retrograde endocannabinoid signaling-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Human cytomegalovirus infection+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Renin secretion-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+Hepatitis B+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Vasopressin-regulated water reabsorption-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Melanogenesis-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Inflammatory mediator regulation of TRP channels-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Vascular smooth muscle contraction-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+Autophagy - animal+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Endocrine and other factor-regulated calcium reabsorption-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Circadian entrainment-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+NF-kappa B signaling pathway+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Pathways of neurodegeneration - multiple diseases-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Parkinson disease-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	"Oscillospira-Parathyroid hormone synthesis, secretion and action-Human papillomavirus infection+C-peptide-GIP"	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Thermogenesis+Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+JAK-STAT signaling pathway-Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Ribosome+Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+Autophagy - animal-Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+NF-kappa B signaling pathway-Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Huntington disease+L-Proline+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Alzheimer disease+L-Proline+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Shigellosis+L-Proline+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Vascular smooth muscle contraction+L-Proline+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Diabetic cardiomyopathy+L-Proline+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+MAPK signaling pathway-L-Proline+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Oxidative phosphorylation+L-Proline+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Pathways of neurodegeneration - multiple diseases+L-Proline+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Cardiac muscle contraction+L-Proline+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Parkinson disease+L-Proline+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Thermogenesis-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+JAK-STAT signaling pathway+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Ribosome-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Dopaminergic synapse-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Retrograde endocannabinoid signaling-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Melanogenesis-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Inflammatory mediator regulation of TRP channels-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Vascular smooth muscle contraction-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+T cell receptor signaling pathway+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Platelet activation-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Oxidative phosphorylation-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+Autophagy - animal+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Circadian entrainment-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+NF-kappa B signaling pathway+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Cardiac muscle contraction-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+FoxO signaling pathway+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Focal adhesion-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+Progesterone-mediated oocyte maturation-n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Human cytomegalovirus infection+n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Shigellosis+n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+MAPK signaling pathway-n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+Progesterone-mediated oocyte maturation+16:0/20:5-PC+blood-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira-Shigellosis-16:0/20:5-PC+blood-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
Oscillospira	GIP	Oscillospira+MAPK signaling pathway+16:0/20:5-PC+blood-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.62	0.374	no	no	no	no	no	no	DM-DS
HCA+blood	GIP	HCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.544	0.374	no	no	no	no	no	no	DM-DS
iso-LCA+stool	GIP	iso-LCA+stool-TCA+stool+L-Proline+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.72	0.374	no	no	no	no	no	no	DM-DS
iso-LCA+stool	GIP	iso-LCA+stool-UDCA+stool+L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.72	0.374	no	no	no	no	no	no	DM-DS
iso-LCA+stool	GIP	iso-LCA+stool-TCA+stool-16:0/22:6-PC+blood-C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.72	0.374	no	no	no	no	no	no	DM-DS
DCA+blood	GIP	DCA+blood+L-Histidine+blood+n6/n3+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.122	0.374	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	GIP	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-d18:1-14:0-SM+blood-n6/n3+blood+C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.374	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	GIP	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood+16:0/20:5-PC+blood-C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.374	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	GIP	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.374	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	GIP	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Tryptophan+blood+C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.374	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	GIP	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Phenylalanine+blood+C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.374	no	no	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	GIP	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-6-IP-10+C-peptide-GIP"	Indirect	urine_cometabolism	DM-associated hormones	0.0125	0.374	up	up	no	no	no	no	DM-DS
nutriCA+blood	GIP	nutriCA+blood+UDCA+blood+Eotaxin-IL-6-IP-10+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.726	0.374	no	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+urine	GIP	4-hydroxybenzoic acid+urine+Homovanillic acid+urine-IP-10+C-peptide-GIP	Indirect	urine_cometabolism	DM-associated hormones	0.52	0.374	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	GIP	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.374	no	no	no	no	no	no	DM-DS
TCA+stool	GIP	TCA+stool+L-Proline+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.458	0.374	no	no	no	no	no	no	DM-DS
TCA+stool	GIP	TCA+stool-16:0/22:6-PC+blood-C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.458	0.374	no	no	no	no	no	no	DM-DS
HDCA+stool	GIP	HDCA+stool+L-2-Aminobutyric acid+blood-L-Proline+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.176	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-Progesterone-mediated oocyte maturation+16:0/20:5-PC+blood-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Carbon metabolism+CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Proteasome+CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Hippo signaling pathway+CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-Progesterone-mediated oocyte maturation-n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-Cytosolic DNA-sensing pathway+n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+TCA+stool-16:0/22:6-PC+blood-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+L-Methionine+blood+L-Tryptophan+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+TCA+stool+L-Proline+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Vascular smooth muscle contraction+L-Proline+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Proteasome+L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-ErbB signaling pathway-L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+L-Methionine+blood+L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Proteasome+Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Glycolysis / Gluconeogenesis+Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-Autophagy - animal-Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-RIG-I-like receptor signaling pathway-Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-ErbB signaling pathway-Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-TNF signaling pathway-Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-JAK-STAT signaling pathway-Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-NF-kappa B signaling pathway-Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Proteasome-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Adherens junction-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Platelet activation-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Glycolysis / Gluconeogenesis-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-T cell receptor signaling pathway+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-Autophagy - animal+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Regulation of actin cytoskeleton-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-RIG-I-like receptor signaling pathway+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Circadian entrainment-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Hippo signaling pathway-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Vascular smooth muscle contraction-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Tight junction-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-FoxO signaling pathway+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-ErbB signaling pathway+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-TNF signaling pathway+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-JAK-STAT signaling pathway+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Focal adhesion-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-NOD-like receptor signaling pathway+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-NF-kappa B signaling pathway+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-Signaling pathways regulating pluripotency of stem cells-L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-ErbB signaling pathway-L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+L-Methionine+blood+L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-Hepatitis B+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-Insulin resistance+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Renin secretion-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-Autophagy - animal+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-Cytosolic DNA-sensing pathway+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-RIG-I-like receptor signaling pathway+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Circadian entrainment-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira+Vascular smooth muscle contraction-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-TNF signaling pathway+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-NOD-like receptor signaling pathway+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Lachnospira	GIP	Lachnospira-NF-kappa B signaling pathway+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.279	0.374	no	no	no	no	no	no	DM-DS
Fusobacterium	GIP	Fusobacterium-18:0/18:0-PC+blood+20:3n6+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.628	0.374	no	no	no	no	no	no	DM-DS
Fusobacterium	GIP	Fusobacterium-16:0/20:3-PC+blood+20:3n6+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.628	0.374	no	no	no	no	no	no	DM-DS
Fusobacterium	GIP	Fusobacterium-18:0/18:1-PC+blood+20:3n6+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.628	0.374	no	no	no	no	no	no	DM-DS
Fusobacterium	GIP	Fusobacterium-Intestinal immune network for IgA production+GCDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.628	0.374	no	no	no	no	no	no	DM-DS
Fusobacterium	GIP	Fusobacterium-18:0/18:0-PC+blood+IP-10+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.628	0.374	no	no	no	no	no	no	DM-DS
Fusobacterium	GIP	Fusobacterium-16:0/20:3-PC+blood+IP-10+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.628	0.374	no	no	no	no	no	no	DM-DS
Fusobacterium	GIP	Fusobacterium-18:0/18:1-PC+blood+IP-10+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.628	0.374	no	no	no	no	no	no	DM-DS
Fusobacterium	GIP	Fusobacterium-16:0/18:1-PC+blood+16:0/22:6-PC+blood-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.628	0.374	no	no	no	no	no	no	DM-DS
Fusobacterium	GIP	Fusobacterium-Intestinal immune network for IgA production-Phenylacetic acid+stool-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.628	0.374	no	no	no	no	no	no	DM-DS
GCDCA+stool	GIP	GCDCA+stool+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.374	no	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	GIP	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.374	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	GIP	5-Hydroxytryptamine+stool-nutriCA+stool+20:3n6+blood+C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.374	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	GIP	5-Hydroxytryptamine+stool-UDCA+stool+L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.374	dn	dn	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Necroptosis+n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Long-term depression+n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Ferroptosis+n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+Salmonella infection+L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Cushing syndrome-L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Endocrine resistance-L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Chemical carcinogenesis - receptor activation-L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+GCA+stool+GCDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+CA+stool+CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Serotonergic synapse-CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+Salmonella infection+CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+Proteasome+CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Cocaine addiction-CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Regulation of lipolysis in adipocytes-CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Glutamatergic synapse-CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Insulin secretion-CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-GnRH signaling pathway-CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Cortisol synthesis and secretion-CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	"Odoribacter-Growth hormone synthesis, secretion and action-CDCA+stool+C-peptide-GIP"	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Endocrine resistance-CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Chemical carcinogenesis - receptor activation-CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+Carbon metabolism+CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+CA+stool+L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Serotonergic synapse-L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+Proteasome+L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+GCA+stool+L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	"Odoribacter-Growth hormone synthesis, secretion and action-L-Tyrosine+blood+C-peptide-GIP"	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Gap junction-L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Chemical carcinogenesis - receptor activation-L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+Proteasome+Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+Glycolysis / Gluconeogenesis+Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Gap junction-Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Ferroptosis-Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+Longevity regulating pathway - multiple species+Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Ferroptosis-16:0/20:5-PC+blood-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+Proteasome-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+Glycolysis / Gluconeogenesis-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+Neuroactive ligand-receptor interaction+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+Fc gamma R-mediated phagocytosis+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+Salmonella infection+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+Pathogenic Escherichia coli infection+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-GnRH signaling pathway-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Cushing syndrome-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter-Cortisol synthesis and secretion-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+Neuroactive ligand-receptor interaction+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Odoribacter	GIP	Odoribacter+Fc gamma R-mediated phagocytosis+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.798	0.374	no	no	no	no	no	no	DM-DS
Actinomyces	GIP	Actinomyces+Coprococcus+L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.621	0.374	no	no	no	no	no	no	DM-DS
Actinomyces	GIP	Actinomyces+Coprococcus+L-Tryptophan+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.621	0.374	no	no	no	no	no	no	DM-DS
Actinomyces	GIP	Actinomyces+Coprococcus+Roseburia+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.621	0.374	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	GIP	Isobutyric acid+stool+Phenylacetic acid+stool-C-peptide-GIP	Indirect	stool_scfa	DM-associated hormones	0.408	0.374	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	GIP	2-hydroxyphenylacetic acid+urine+Homovanillic acid+urine-IP-10+C-peptide-GIP	Indirect	urine_cometabolism	DM-associated hormones	0.763	0.374	no	no	no	no	no	no	DM-DS
Kynurenic acid+stool	GIP	Kynurenic acid+stool+L-Phenylalanine+stool+Phenylacetic acid+stool-C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.374	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	GIP	Kynurenic acid+stool-nutriCA+stool+20:3n6+blood+C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.374	dn	dn	no	no	no	no	DM-DS
Caproic acid+stool	GIP	Caproic acid+stool+Phenylacetic acid+stool-C-peptide-GIP	Indirect	stool_scfa	DM-associated hormones	0.882	0.374	no	no	no	no	no	no	DM-DS
Eggerthella	GIP	Eggerthella-Yersinia infection+L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.912	0.374	no	no	no	no	no	no	DM-DS
Eggerthella	GIP	Eggerthella+Phosphatidylinositol signaling system-L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.912	0.374	no	no	no	no	no	no	DM-DS
Eggerthella	GIP	Eggerthella-Influenza A+L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.912	0.374	no	no	no	no	no	no	DM-DS
Eggerthella	GIP	Eggerthella+nutriCA+stool+20:3n6+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.912	0.374	no	no	no	no	no	no	DM-DS
Eggerthella	GIP	Eggerthella+AMPK signaling pathway-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.912	0.374	no	no	no	no	no	no	DM-DS
Eggerthella	GIP	Eggerthella-Yersinia infection+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.912	0.374	no	no	no	no	no	no	DM-DS
Eggerthella	GIP	Eggerthella-Influenza A+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.912	0.374	no	no	no	no	no	no	DM-DS
Eggerthella	GIP	Eggerthella+AMPK signaling pathway-CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.912	0.374	no	no	no	no	no	no	DM-DS
Anaerotruncus	GIP	Anaerotruncus-Ruminococcus+L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.904	0.374	no	no	no	no	no	no	DM-DS
Anaerotruncus	GIP	Anaerotruncus-Ruminococcus+IP-10+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.904	0.374	no	no	no	no	no	no	DM-DS
Anaerostipes	GIP	Anaerostipes-Neutrophil extracellular trap formation+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.568	0.374	no	no	no	no	no	no	DM-DS
Anaerostipes	GIP	Anaerostipes+RNA degradation-Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.568	0.374	no	no	no	no	no	no	DM-DS
Anaerostipes	GIP	Anaerostipes+L-2-Aminobutyric acid+blood-L-Proline+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.568	0.374	no	no	no	no	no	no	DM-DS
Anaerostipes	GIP	Anaerostipes-Alcoholism-IP-10+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.568	0.374	no	no	no	no	no	no	DM-DS
Anaerostipes	GIP	Anaerostipes-TDCA+blood-IP-10+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.568	0.374	no	no	no	no	no	no	DM-DS
Anaerostipes	GIP	Anaerostipes-GDCA+blood-IP-10+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.568	0.374	no	no	no	no	no	no	DM-DS
Anaerostipes	GIP	Anaerostipes-IL-6-IP-10+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.568	0.374	no	no	no	no	no	no	DM-DS
Anaerostipes	GIP	Anaerostipes-Neutrophil extracellular trap formation+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.568	0.374	no	no	no	no	no	no	DM-DS
Anaerostipes	GIP	Anaerostipes+RNA degradation-Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.568	0.374	no	no	no	no	no	no	DM-DS
Anaerostipes	GIP	Anaerostipes+Propionic acid+stool-L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.568	0.374	no	no	no	no	no	no	DM-DS
Anaerostipes	GIP	Anaerostipes+RNA degradation+Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.568	0.374	no	no	no	no	no	no	DM-DS
TUDCA+stool	GIP	TUDCA+stool-d18:1-14:0-SM+blood-n6/n3+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.241	0.374	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	GIP	Isovaleric acid+stool+Phenylacetic acid+stool-C-peptide-GIP	Indirect	stool_scfa	DM-associated hormones	0.343	0.374	no	no	no	no	no	no	DM-DS
Paraprevotella	GIP	Paraprevotella+IP-10+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.118	0.374	no	no	no	no	no	no	DM-DS
Homovanillic acid+urine	GIP	Homovanillic acid+urine-IP-10+C-peptide-GIP	Indirect	urine_cometabolism	DM-associated hormones	0.45	0.374	no	no	no	no	no	no	DM-DS
TDCA+blood	GIP	TDCA+blood-IP-10+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.155	0.374	no	up	no	no	no	no	DM-DS
¦Ø-MCA+stool	GIP	¦Ø-MCA+stool+CDCA+stool+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.919	0.374	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	GIP	Phenylacetic acid+stool-C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.374	no	no	no	no	no	no	DM-DS
Gemmiger	GIP	Gemmiger+ErbB signaling pathway-L-Tyrosine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.595	0.374	no	no	no	no	no	no	DM-DS
Gemmiger	GIP	Gemmiger+ErbB signaling pathway-Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.595	0.374	no	no	no	no	no	no	DM-DS
Gemmiger	GIP	Gemmiger+ErbB signaling pathway+Prolactin signaling pathway+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.595	0.374	no	no	no	no	no	no	DM-DS
Gemmiger	GIP	Gemmiger+Signaling pathways regulating pluripotency of stem cells-L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.595	0.374	no	no	no	no	no	no	DM-DS
Gemmiger	GIP	Gemmiger+ErbB signaling pathway-L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.595	0.374	no	no	no	no	no	no	DM-DS
Gemmiger	GIP	Gemmiger+Colorectal cancer-L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.595	0.374	no	no	no	no	no	no	DM-DS
Gemmiger	GIP	Gemmiger+Gastric cancer-L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.595	0.374	no	no	no	no	no	no	DM-DS
GDCA+stool	GIP	GDCA+stool-Phenylacetic acid+stool-C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.656	0.374	no	no	no	no	no	no	DM-DS
GDCA+stool	GIP	GDCA+stool+L-Phenylalanine+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.656	0.374	no	no	no	no	no	no	DM-DS
GDCA+stool	GIP	GDCA+stool+L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.656	0.374	no	no	no	no	no	no	DM-DS
GDCA+stool	GIP	GDCA+stool+IP-10+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.656	0.374	no	no	no	no	no	no	DM-DS
GDCA+stool	GIP	GDCA+stool+L-Tryptophan+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.656	0.374	no	no	no	no	no	no	DM-DS
Methanobrevibacter	GIP	Methanobrevibacter+Methanosphaera-Roseburia+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.629	0.374	no	no	no	no	no	no	DM-DS
Methanobrevibacter	GIP	Methanobrevibacter-Alcoholism-IP-10+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.629	0.374	no	no	no	no	no	no	DM-DS
Methanobrevibacter	GIP	Methanobrevibacter-Cystine+blood+n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.629	0.374	no	no	no	no	no	no	DM-DS
Methanobrevibacter	GIP	Methanobrevibacter+d18:1-14:0-SM+blood-n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.629	0.374	no	no	no	no	no	no	DM-DS
Methanobrevibacter	GIP	Methanobrevibacter-Cystine+blood+L-Tryptophan+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.629	0.374	no	no	no	no	no	no	DM-DS
Methanobrevibacter	GIP	Methanobrevibacter-Cystine+blood+L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.629	0.374	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	GIP	L-Tyrosine+stool-nutriCA+stool+20:3n6+blood+C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.374	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	GIP	L-Tyrosine+stool-18:2/20:4-PC+blood-L-Phenylalanine+blood+C-peptide-GIP	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.374	no	no	no	no	no	no	DM-DS
CDCA+stool	GIP	CDCA+stool+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.663	0.374	no	no	no	no	no	no	DM-DS
CA+stool	GIP	CA+stool+L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.827	0.374	no	no	no	no	no	no	DM-DS
CA+stool	GIP	CA+stool+CDCA+stool+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.827	0.374	no	no	no	no	no	no	DM-DS
HDCA+blood	GIP	HDCA+blood+Hypotaurine+blood+n6/n3+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.483	0.374	no	no	no	no	no	no	DM-DS
UDCA+stool	GIP	UDCA+stool+L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.266	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood-n6/n3+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-d18:1-16:0-SM+blood+d18:1-20:0-SM+blood-n6/n3+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-16:0/22:6-PE+blood-n6/n3+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood+Ethanolamine+blood+n6/n3+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-HDCA+blood+Hypotaurine+blood+n6/n3+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-18:0/22:6-PI+blood-n6/n3+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-18:0/22:6-PE+blood-n6/n3+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-n6/n3+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood-16:0/22:6-PC+blood-C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood-16:0/20:5-PC+blood-C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood+16:0/20:5-PC+blood-C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PE+blood+L-Proline+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PE+blood+L-Proline+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood+L-Proline+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-d18:1-16:0-SM+blood+d18:1-20:1-SM+blood-L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-18:2/18:2-PS+blood+20:3n6+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-16:1/18:1-PG+blood+20:3n6+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PI+blood+20:3n6+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-18:0/20:3-PI+blood+20:3n6+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-18:1/16:1-PE+blood+20:3n6+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood+20:3n6+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood+20:3n6+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood+20:3n6+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood+d18:1-22:0-SM+blood+IP-10+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood+d18:0-24:1-SM+blood+IP-10+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood-20:4/18:0-PE+blood-IP-10+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
TDCA+stool	GIP	TDCA+stool-12-ketoDCA+blood+GDCA+blood-IP-10+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.963	0.374	no	no	no	no	no	no	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	GIP	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2-IP-10+C-peptide-GIP	Indirect	urine_cometabolism	DM-associated hormones	0.973	0.374	no	no	no	no	no	no	DM-DS
Desulfovibrio	GIP	Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.27	0.374	no	no	no	no	no	no	DM-DS
Desulfovibrio	GIP	Desulfovibrio+Human cytomegalovirus infection+n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.27	0.374	no	no	no	no	no	no	DM-DS
Desulfovibrio	GIP	Desulfovibrio+Human immunodeficiency virus 1 infection+n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.27	0.374	no	no	no	no	no	no	DM-DS
Desulfovibrio	GIP	Desulfovibrio+Human cytomegalovirus infection+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.27	0.374	no	no	no	no	no	no	DM-DS
Desulfovibrio	GIP	Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.27	0.374	no	no	no	no	no	no	DM-DS
Desulfovibrio	GIP	Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.27	0.374	no	no	no	no	no	no	DM-DS
Desulfovibrio	GIP	Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.27	0.374	no	no	no	no	no	no	DM-DS
nutriCA+stool	GIP	nutriCA+stool+20:3n6+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.481	0.374	no	no	no	no	no	no	DM-DS
Bilophila	GIP	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.528	0.374	no	no	no	no	no	no	DM-DS
Bilophila	GIP	Bilophila+Desulfovibrio+Human cytomegalovirus infection+n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.528	0.374	no	no	no	no	no	no	DM-DS
Bilophila	GIP	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+n6/n3+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.528	0.374	no	no	no	no	no	no	DM-DS
Bilophila	GIP	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Human papillomavirus infection+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.528	0.374	no	no	no	no	no	no	DM-DS
Bilophila	GIP	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.528	0.374	no	no	no	no	no	no	DM-DS
Bilophila	GIP	Bilophila+Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.528	0.374	no	no	no	no	no	no	DM-DS
Bilophila	GIP	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.528	0.374	no	no	no	no	no	no	DM-DS
GDCA+blood	GIP	GDCA+blood-IP-10+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.632	0.374	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	GIP	P-hydroxyhippuric acid+urine+Eotaxin-IL-6-IP-10+C-peptide-GIP	Indirect	urine_cometabolism	DM-associated hormones	0.436	0.374	no	no	no	no	no	no	DM-DS
acetic acid C2+blood	GIP	acetic acid C2+blood+d18:1-20:1-SM+blood-L-Tyrosine+blood+C-peptide-GIP	Indirect	serum_scfa	DM-associated hormones	0.000193	0.374	up	dn	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	GIP	isovaleric acid iso-C5+blood-L-Phenylalanine+blood+C-peptide-GIP	Indirect	serum_scfa	DM-associated hormones	0.117	0.374	no	no	no	no	no	no	DM-DS
Clostridium	GIP	Clostridium+Long-term potentiation-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.925	0.374	no	no	no	no	no	no	DM-DS
Clostridium	GIP	Clostridium+L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.925	0.374	no	no	no	no	no	no	DM-DS
Clostridium	GIP	Clostridium-16:0/20:5-PC+blood-C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.925	0.374	no	no	no	no	no	no	DM-DS
Clostridium	GIP	Clostridium+CDCA+stool+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.925	0.374	no	no	no	no	no	no	DM-DS
Clostridium	GIP	Clostridium+20:3n6+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.925	0.374	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	GIP	T-¦Á-MCA+stool-UDCA+stool+L-Tyrosine+blood+C-peptide-GIP	Indirect	stool_bileacids	DM-associated hormones	0.48	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-18:1/18:1-PE+blood+20:3n6+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-16:0/18:1-PE+blood+20:3n6+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-18:1/18:0-PE+blood+20:3n6+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-18:1/16:1-PE+blood+20:3n6+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-18:2/18:2-PS+blood+20:3n6+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-18:0/18:1-PI+blood+20:3n6+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-16:1/18:1-PG+blood+20:3n6+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-18:0/20:3-PI+blood+20:3n6+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-18:1/18:0-PE+blood+L-Proline+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-18:0/18:1-PE+blood+L-Proline+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-18:0/18:0-PE+blood+L-Proline+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood+GDCA+blood-IP-10+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood+d18:0-24:1-SM+blood+IP-10+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-20:4/18:0-PE+blood-IP-10+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood+d18:1-22:0-SM+blood+IP-10+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-16:0/18:1-PE+blood-16:0/22:6-PC+blood-C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-16:0/18:1-PE+blood-16:0/20:5-PC+blood-C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-16:0/18:0-PS+blood+16:0/20:5-PC+blood-C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-18:0/18:0-PS+blood-n6/n3+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood+Ethanolamine+blood+n6/n3+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-18:0/22:6-PI+blood-n6/n3+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-16:0/18:0-PS+blood-n6/n3+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-16:0/22:6-PE+blood-n6/n3+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	GIP	12-ketoDCA+blood-18:0/22:6-PE+blood-n6/n3+blood+C-peptide-GIP	Indirect	serum_bileacids	DM-associated hormones	0.517	0.374	no	no	no	no	no	no	DM-DS
Butyricicoccus	GIP	Butyricicoccus-18:2/20:4-PC+blood-L-Phenylalanine+blood+C-peptide-GIP	Indirect	Genus	DM-associated hormones	0.852	0.374	no	no	no	no	no	no	DM-DS
Blautia	IL-6	Blautia+Dorea-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia+Dorea+Carbon metabolism+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Cocaine addiction-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Thyroid hormone synthesis-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia+Peroxisome+Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Dopaminergic synapse-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Calcium signaling pathway-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia+Peroxisome-Adherens junction+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Calcium signaling pathway+Adherens junction+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Cocaine addiction-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Thyroid hormone synthesis-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia+Peroxisome+Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Calcium signaling pathway-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia+Peroxisome-Focal adhesion+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia+Peroxisome+IL-17 signaling pathway+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Calcium signaling pathway-IL-17 signaling pathway+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Cocaine addiction+Chemical carcinogenesis - receptor activation-IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Thyroid hormone synthesis+Chemical carcinogenesis - receptor activation-IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Calcium signaling pathway+Chemical carcinogenesis - receptor activation-IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia+Longevity regulating pathway - multiple species-Chemical carcinogenesis - receptor activation-IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia+Peroxisome+JAK-STAT signaling pathway-IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Calcium signaling pathway-JAK-STAT signaling pathway-IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia+Peroxisome-Platelet activation+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Calcium signaling pathway+Platelet activation+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Cocaine addiction-Epstein-Barr virus infection+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia+Peroxisome-Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Dopaminergic synapse+Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Calcium signaling pathway+Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia+Peroxisome-Spinocerebellar ataxia-IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Calcium signaling pathway-FoxO signaling pathway-IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Cocaine addiction-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Thyroid hormone synthesis-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Blautia	IL-6	Blautia-Dopaminergic synapse-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-DS
Parabacteroides	IL-6	Parabacteroides+Alistipes-IL-6	Indirect	Genus	serum_cytokines	4.19E-05	0.52	no	up	up	no	no	no	DM-DS
Parabacteroides	IL-6	Parabacteroides+MAPK signaling pathway-IL-6	Indirect	Genus	serum_cytokines	4.19E-05	0.52	no	up	up	no	no	no	DM-DS
Dorea	IL-6	Dorea+Carbon metabolism+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	DM-DS
Dorea	IL-6	Dorea-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	DM-DS
Faecalibacterium	IL-6	Faecalibacterium-Phenylacetic acid+stool-UDCA+blood+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.0039	0.52	no	dn	dn	no	no	no	DM-DS
Bacteroides	IL-6	Bacteroides-Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.000267	0.52	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-6	Bacteroides+Leishmaniasis+IL-6	Indirect	Genus	serum_cytokines	0.000267	0.52	dn	dn	up	no	no	no	DM-DS
Propionic acid+stool	IL-6	Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.0436	0.52	dn	no	up	no	no	no	DM-DS
[Ruminococcus]	IL-6	[Ruminococcus]+Tight junction+IL-6	Indirect	Genus	serum_cytokines	0.0679	0.52	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-6	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells-IL-6	Indirect	Genus	serum_cytokines	0.0679	0.52	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-6	[Ruminococcus]-FoxO signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.0679	0.52	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-6	[Ruminococcus]-Progesterone-mediated oocyte maturation-IL-6	Indirect	Genus	serum_cytokines	0.0679	0.52	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-6	[Ruminococcus]-ErbB signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.0679	0.52	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-6	[Ruminococcus]-JAK-STAT signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.0679	0.52	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-6	[Ruminococcus]-Gastric cancer-IL-6	Indirect	Genus	serum_cytokines	0.0679	0.52	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-6	[Ruminococcus]-Platinum drug resistance-IL-6	Indirect	Genus	serum_cytokines	0.0679	0.52	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-6	[Ruminococcus]-Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.0679	0.52	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-6	[Ruminococcus]-Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.0679	0.52	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-6	[Ruminococcus]-Pancreatic cancer-IL-6	Indirect	Genus	serum_cytokines	0.0679	0.52	no	no	dn	no	no	no	DM-DS
GUDCA+blood	IL-6	GUDCA+blood+UDCA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.0766	0.52	no	no	dn	no	no	no	DM-DS
UDCA+blood	IL-6	UDCA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.0939	0.52	no	no	dn	no	no	no	DM-DS
Acetic acid+stool	IL-6	Acetic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.0656	0.52	dn	no	no	no	no	no	DM-DS
Alistipes	IL-6	Alistipes-IL-6	Direct	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Non-alcoholic fatty liver disease-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Amyotrophic lateral sclerosis-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+AGE-RAGE signaling pathway in diabetic complications+Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Huntington disease-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+GABAergic synapse+Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Pathways of neurodegeneration - multiple diseases-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Parkinson disease-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Non-alcoholic fatty liver disease-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Amyotrophic lateral sclerosis-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+AGE-RAGE signaling pathway in diabetic complications+Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Huntington disease-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Pathways of neurodegeneration - multiple diseases-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Parkinson disease-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Non-alcoholic fatty liver disease+Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Amyotrophic lateral sclerosis+Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+AGE-RAGE signaling pathway in diabetic complications-Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Huntington disease+Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+GABAergic synapse-Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Pathways of neurodegeneration - multiple diseases+Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Parkinson disease+Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+Type II diabetes mellitus-Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+AGE-RAGE signaling pathway in diabetic complications-Spinocerebellar ataxia-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+GABAergic synapse-Spinocerebellar ataxia-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+AGE-RAGE signaling pathway in diabetic complications+Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+Type II diabetes mellitus+Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Amyotrophic lateral sclerosis-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+AGE-RAGE signaling pathway in diabetic complications+Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Huntington disease-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Pathways of neurodegeneration - multiple diseases-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Parkinson disease-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Amyotrophic lateral sclerosis-Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+AGE-RAGE signaling pathway in diabetic complications+Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Huntington disease-Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+GABAergic synapse+Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Parkinson disease-Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+Type II diabetes mellitus+Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+AGE-RAGE signaling pathway in diabetic complications-Bacterial invasion of epithelial cells+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+Type II diabetes mellitus-Bacterial invasion of epithelial cells+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas-L-Asparagine+blood+L-Citrulline+blood+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas-iso-DCA+blood+L-Citrulline+blood+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas-Butyric acid+stool+L-Citrulline+blood+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas-Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+Type II diabetes mellitus+Pancreatic cancer-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+12-ketoDCA+stool+Hippuric acid+urine-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+20:5n3+blood-DMG+blood-Hippuric acid+urine-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+18:0+blood-DMG+blood-Hippuric acid+urine-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas-Creatinine+blood+DMG+blood-Hippuric acid+urine-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+AGE-RAGE signaling pathway in diabetic complications-Leishmaniasis+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+Type II diabetes mellitus-Leishmaniasis+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+Type II diabetes mellitus-Fluid shear stress and atherosclerosis+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+Type II diabetes mellitus+Gastric cancer-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse+Type II diabetes mellitus+Chemical carcinogenesis - receptor activation-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-6	Butyricimonas+Cholinergic synapse-Kaposi sarcoma-associated herpesvirus infection+Epstein-Barr virus infection+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-Renin secretion+Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-Endocrine and other factor-regulated calcium reabsorption+Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-Inflammatory mediator regulation of TRP channels+Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-GnRH signaling pathway-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-Renin secretion-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-Endocrine and other factor-regulated calcium reabsorption-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-Inflammatory mediator regulation of TRP channels-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-GnRH signaling pathway-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-Renin secretion-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-Endocrine and other factor-regulated calcium reabsorption-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-Inflammatory mediator regulation of TRP channels-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-GnRH signaling pathway-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-Renin secretion-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-Endocrine and other factor-regulated calcium reabsorption-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-Inflammatory mediator regulation of TRP channels-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-GnRH signaling pathway+Chemical carcinogenesis - receptor activation-IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-Endocrine and other factor-regulated calcium reabsorption+Chemical carcinogenesis - receptor activation-IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-GnRH signaling pathway-Epstein-Barr virus infection+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-Renin secretion+Bacterial invasion of epithelial cells+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
Collinsella	IL-6	Collinsella-Renin secretion-Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-DS
5-Hydroxytryptamine+urine	IL-6	5-Hydroxytryptamine+urine-Hippuric acid+urine-IL-6	Indirect	urine_cometabolism	serum_cytokines	0.171	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Osteoclast differentiation+IL-17 signaling pathway+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Cellular senescence+IL-17 signaling pathway+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Apoptosis+IL-17 signaling pathway+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway+IL-17 signaling pathway+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Toll-like receptor signaling pathway+IL-17 signaling pathway+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+RIG-I-like receptor signaling pathway+IL-17 signaling pathway+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+C-type lectin receptor signaling pathway+IL-17 signaling pathway+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Osteoclast differentiation+JAK-STAT signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Apoptosis+JAK-STAT signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway+JAK-STAT signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Toll-like receptor signaling pathway+JAK-STAT signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+RIG-I-like receptor signaling pathway+JAK-STAT signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+C-type lectin receptor signaling pathway+JAK-STAT signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Osteoclast differentiation+T cell receptor signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway+T cell receptor signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Toll-like receptor signaling pathway+T cell receptor signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+RIG-I-like receptor signaling pathway+T cell receptor signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+C-type lectin receptor signaling pathway+T cell receptor signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Th17 cell differentiation+T cell receptor signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Glucagon signaling pathway+Chemical carcinogenesis - receptor activation-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Cellular senescence-Chemical carcinogenesis - receptor activation-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Amphetamine addiction+Chemical carcinogenesis - receptor activation-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-GnRH signaling pathway+Chemical carcinogenesis - receptor activation-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Aldosterone synthesis and secretion+Chemical carcinogenesis - receptor activation-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Cellular senescence+Antigen processing and presentation+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Acute myeloid leukemia+Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Human papillomavirus infection+Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway+Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Insulin resistance+Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Circadian entrainment-Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Neurotrophin signaling pathway+Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Chronic myeloid leukemia+Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Toll-like receptor signaling pathway+Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+RIG-I-like receptor signaling pathway+Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Fc epsilon RI signaling pathway+Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Prostate cancer+Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+C-type lectin receptor signaling pathway+Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Prolactin signaling pathway+Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+TNF signaling pathway+Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+B cell receptor signaling pathway+Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Cellular senescence+Epstein-Barr virus infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-GnRH signaling pathway-Epstein-Barr virus infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway-Asthma+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Insulin resistance-Asthma+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+RIG-I-like receptor signaling pathway-Asthma+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway-Focal adhesion+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway-Bacterial invasion of epithelial cells+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Insulin resistance-Bacterial invasion of epithelial cells+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Circadian entrainment+Bacterial invasion of epithelial cells+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+RIG-I-like receptor signaling pathway-Bacterial invasion of epithelial cells+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+TNF signaling pathway-Bacterial invasion of epithelial cells+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway-Fluid shear stress and atherosclerosis+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Insulin resistance-Fluid shear stress and atherosclerosis+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Circadian entrainment+Fluid shear stress and atherosclerosis+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Chronic myeloid leukemia-Fluid shear stress and atherosclerosis+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+RIG-I-like receptor signaling pathway-Fluid shear stress and atherosclerosis+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Prostate cancer-Fluid shear stress and atherosclerosis+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Glucagon signaling pathway-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Osteoclast differentiation+Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Inflammatory mediator regulation of TRP channels-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Dopaminergic synapse-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Cellular senescence+Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Apoptosis+Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Amphetamine addiction-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Neurotrophin signaling pathway+Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Toll-like receptor signaling pathway+Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-GnRH signaling pathway-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Aldosterone synthesis and secretion-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Fc epsilon RI signaling pathway+Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+C-type lectin receptor signaling pathway+Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Prolactin signaling pathway+Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Th17 cell differentiation+Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+B cell receptor signaling pathway+Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway-Cell cycle-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Glucagon signaling pathway+Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Osteoclast differentiation-Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Inflammatory mediator regulation of TRP channels+Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Dopaminergic synapse+Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway-Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Insulin resistance-Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Amphetamine addiction+Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Circadian entrainment+Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Neurotrophin signaling pathway-Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Toll-like receptor signaling pathway-Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+RIG-I-like receptor signaling pathway-Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Fc epsilon RI signaling pathway-Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+C-type lectin receptor signaling pathway-Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Prolactin signaling pathway-Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+TNF signaling pathway-Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+B cell receptor signaling pathway-Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway+FoxO signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway-Leishmaniasis+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Osteoclast differentiation-Adherens junction+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway-Adherens junction+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway-Oxytocin signaling pathway+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Circadian entrainment+Oxytocin signaling pathway+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+RIG-I-like receptor signaling pathway-Oxytocin signaling pathway+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+TNF signaling pathway-Oxytocin signaling pathway+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway+Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Insulin resistance+Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Neurotrophin signaling pathway+Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Toll-like receptor signaling pathway+Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+RIG-I-like receptor signaling pathway+Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Fc epsilon RI signaling pathway+Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+C-type lectin receptor signaling pathway+Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Prolactin signaling pathway+Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+TNF signaling pathway+Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+B cell receptor signaling pathway+Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway-Platelet activation+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway-Regulation of actin cytoskeleton+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Circadian entrainment+Regulation of actin cytoskeleton+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Neurotrophin signaling pathway-Regulation of actin cytoskeleton+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Toll-like receptor signaling pathway-Regulation of actin cytoskeleton+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+RIG-I-like receptor signaling pathway-Regulation of actin cytoskeleton+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Fc epsilon RI signaling pathway-Regulation of actin cytoskeleton+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+C-type lectin receptor signaling pathway-Regulation of actin cytoskeleton+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+TNF signaling pathway-Regulation of actin cytoskeleton+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+B cell receptor signaling pathway-Regulation of actin cytoskeleton+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Viral carcinogenesis+Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Glucagon signaling pathway-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Osteoclast differentiation+Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Inflammatory mediator regulation of TRP channels-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Cellular senescence+Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Human papillomavirus infection+Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Apoptosis+Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Amphetamine addiction-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Toll-like receptor signaling pathway+Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-GnRH signaling pathway-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Aldosterone synthesis and secretion-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Fc epsilon RI signaling pathway+Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+C-type lectin receptor signaling pathway+Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+B cell receptor signaling pathway+Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Glucagon signaling pathway+Spinocerebellar ataxia-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Osteoclast differentiation-Spinocerebellar ataxia-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Apoptosis-Spinocerebellar ataxia-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Toll-like receptor signaling pathway-Spinocerebellar ataxia-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Aldosterone synthesis and secretion+Spinocerebellar ataxia-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Fc epsilon RI signaling pathway-Spinocerebellar ataxia-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+B cell receptor signaling pathway-Spinocerebellar ataxia-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Insulin resistance+Gastric cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Chronic myeloid leukemia+Gastric cancer-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+NF-kappa B signaling pathway-Tight junction+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Glucagon signaling pathway-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Osteoclast differentiation+Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Inflammatory mediator regulation of TRP channels-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Dopaminergic synapse-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Cellular senescence+Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Apoptosis+Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Amphetamine addiction-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Toll-like receptor signaling pathway+Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-GnRH signaling pathway-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina-Aldosterone synthesis and secretion-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Fc epsilon RI signaling pathway+Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+C-type lectin receptor signaling pathway+Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+Prolactin signaling pathway+Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Sarcina	IL-6	Sarcina+B cell receptor signaling pathway+Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-6	Methanosphaera-Roseburia+16:0/18:2-PI+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.0703	0.52	no	no	no	no	no	no	DM-DS
iso-DCA+stool	IL-6	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.155	0.52	no	no	no	no	no	no	DM-DS
LCA+stool	IL-6	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.314	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Breast cancer+Gastric cancer-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Longevity regulating pathway-Platelet activation+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Longevity regulating pathway-Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Cytokine-cytokine receptor interaction+Staphylococcus aureus infection+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Longevity regulating pathway+Hippuric acid+urine-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Breast cancer+Hippuric acid+urine-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Longevity regulating pathway-Leishmaniasis+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Longevity regulating pathway-Adherens junction+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Longevity regulating pathway-Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Cytokine-cytokine receptor interaction+Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Longevity regulating pathway-Leukocyte transendothelial migration+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Longevity regulating pathway-Regulation of actin cytoskeleton+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia+P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Longevity regulating pathway-Asthma+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Breast cancer-Asthma+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Longevity regulating pathway-Tight junction+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Longevity regulating pathway-Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Cytokine-cytokine receptor interaction+Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Longevity regulating pathway-Bacterial invasion of epithelial cells+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Longevity regulating pathway+Chemical carcinogenesis - receptor activation-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Longevity regulating pathway-Focal adhesion+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Longevity regulating pathway-Fluid shear stress and atherosclerosis+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Breast cancer-Fluid shear stress and atherosclerosis+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Cytokine-cytokine receptor interaction+IL-17 signaling pathway+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Cytokine-cytokine receptor interaction-Spinocerebellar ataxia-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Akkermansia	IL-6	Akkermansia-Cytokine-cytokine receptor interaction-Signaling pathways regulating pluripotency of stem cells-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-DS
Bifidobacterium	IL-6	Bifidobacterium+Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.105	0.52	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-6	Bifidobacterium-FoxO signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.105	0.52	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-6	Bifidobacterium+Tight junction+IL-6	Indirect	Genus	serum_cytokines	0.105	0.52	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-6	Bifidobacterium+Bacterial invasion of epithelial cells+IL-6	Indirect	Genus	serum_cytokines	0.105	0.52	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-6	Bifidobacterium+Focal adhesion+IL-6	Indirect	Genus	serum_cytokines	0.105	0.52	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-6	Bifidobacterium+Leukocyte transendothelial migration+IL-6	Indirect	Genus	serum_cytokines	0.105	0.52	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-6	Bifidobacterium+Adherens junction+IL-6	Indirect	Genus	serum_cytokines	0.105	0.52	no	dn	no	no	no	no	DM-DS
3-Hydroxytyramine hydrochloride+urine	IL-6	3-Hydroxytyramine hydrochloride+urine-Hippuric acid+urine-IL-6	Indirect	urine_cometabolism	serum_cytokines	0.288	0.52	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-6	Ruminococcus-Alcoholism-Gastric cancer-IL-6	Indirect	Genus	serum_cytokines	0.335	0.52	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-6	Ruminococcus-Alcoholism+Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.335	0.52	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-6	Ruminococcus-Serotonergic synapse-Spinocerebellar ataxia-IL-6	Indirect	Genus	serum_cytokines	0.335	0.52	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-6	Ruminococcus-Serotonergic synapse-Pancreatic cancer-IL-6	Indirect	Genus	serum_cytokines	0.335	0.52	no	no	no	no	no	no	DM-DS
GCDCA+blood	IL-6	GCDCA+blood+GUDCA+blood+UDCA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.31	0.52	no	no	no	no	no	no	DM-DS
GCDCA+blood	IL-6	GCDCA+blood+HCA+blood+UDCA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.31	0.52	no	no	no	no	no	no	DM-DS
ACA+blood	IL-6	ACA+blood+EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.338	0.52	no	no	no	no	no	no	DM-DS
DCA+stool	IL-6	DCA+stool+HDCA+stool+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.195	0.52	no	no	no	no	no	no	DM-DS
DCA+stool	IL-6	DCA+stool+HDCA+stool+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.195	0.52	no	no	no	no	no	no	DM-DS
Hippuric acid+urine	IL-6	Hippuric acid+urine-IL-6	Direct	urine_cometabolism	serum_cytokines	0.361	0.52	no	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-6	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.102	0.52	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-6	Butyric acid+stool+L-Citrulline+blood+Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.102	0.52	dn	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	IL-6	4-hydroxybenzoic acid+stool-DCA+stool+HDCA+stool+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.52	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	IL-6	4-hydroxybenzoic acid+stool-DCA+stool+HDCA+stool+Hippuric acid+urine-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.52	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	IL-6	4-hydroxybenzoic acid+stool+L-Tryptophan+stool-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.52	no	dn	no	no	no	no	DM-DS
Turicibacter	IL-6	Turicibacter+Desulfovibrio+Antigen processing and presentation+IL-6	Indirect	Genus	serum_cytokines	0.269	0.52	no	no	no	no	no	no	DM-DS
GCA+blood	IL-6	GCA+blood+HCA+blood+UDCA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.16	0.52	no	no	no	no	no	no	DM-DS
ACA+stool	IL-6	ACA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.417	0.52	no	no	no	no	no	no	DM-DS
ACA+stool	IL-6	ACA+stool-L-Tryptophan+stool-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.417	0.52	no	no	no	no	no	no	DM-DS
ACA+stool	IL-6	ACA+stool-L-Phenylalanine+stool-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.417	0.52	no	no	no	no	no	no	DM-DS
CDCA+blood	IL-6	CDCA+blood+UDCA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.506	0.52	no	no	no	no	no	no	DM-DS
capric acid C6+blood	IL-6	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.433	0.52	no	no	no	no	no	no	DM-DS
Prevotella	IL-6	Prevotella-Tight junction+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	DM-DS
Prevotella	IL-6	Prevotella-Bacterial invasion of epithelial cells+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	DM-DS
Prevotella	IL-6	Prevotella+FoxO signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	DM-DS
Prevotella	IL-6	Prevotella+Hippuric acid+urine-IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	DM-DS
Prevotella	IL-6	Prevotella-Focal adhesion+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	DM-DS
iso-DCA+blood	IL-6	iso-DCA+blood+L-Citrulline+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.38	0.52	no	no	no	no	no	no	DM-DS
HCA+stool	IL-6	HCA+stool-HDCA+stool+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.155	0.52	no	no	no	no	no	no	DM-DS
HCA+stool	IL-6	HCA+stool-HDCA+stool+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.155	0.52	no	no	no	no	no	no	DM-DS
Roseburia	IL-6	Roseburia+16:0/18:2-PI+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.495	0.52	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	IL-6	12-ketoDCA+stool+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.505	0.52	no	no	no	no	no	no	DM-DS
GLCA+blood	IL-6	GLCA+blood-SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.319	0.52	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-6	L-Tryptophan+stool-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.557	0.52	no	no	no	no	no	no	DM-DS
CA+blood	IL-6	CA+blood+UDCA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.606	0.52	no	no	no	no	no	no	DM-DS
GUDCA+stool	IL-6	GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0085	0.52	no	dn	no	no	no	no	DM-DS
GUDCA+stool	IL-6	GUDCA+stool+12-HEPE+blood-DMG+blood-Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0085	0.52	no	dn	no	no	no	no	DM-DS
L-Phenylalanine+stool	IL-6	L-Phenylalanine+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.398	0.52	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	IL-6	L-Phenylalanine+stool-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.398	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool+GCDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool+GDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool+DPA+blood-nutriCA+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool+GCDCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-Isovaleric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-Isobutyric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool+GCDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool+UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool+GDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-iso-LCA+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool+GCDCA+stool+16:0/16:1-PC+blood+16:0/18:2-PI+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool+GCDCA+stool+16:1/18:2-PG+blood+18:0/18:2-PI+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool+GCDCA+stool+16:0/18:2-PC+blood-16:0/20:4-PI+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	"GCA+stool+GDCA+stool+L-Lysine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-6"	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool+GCDCA+stool+16:0/16:1-PC+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-12-ketoDCA+blood-16:0/20:4-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-12-ketoDCA+blood-18:0/18:1-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-12-ketoDCA+blood-18:1/16:0-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-12-ketoDCA+blood-18:1/16:1-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool+GCDCA+stool-L-Phenylalanine+stool-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-Isovaleric acid+stool+L-Phenylalanine+stool-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool-Isobutyric acid+stool+L-Phenylalanine+stool-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool+GCDCA+stool+16:0/18:2-PC+blood-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
GCA+stool	IL-6	GCA+stool+GCDCA+stool+18:1/16:0-PC+blood-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-DS
Coprococcus	IL-6	Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	DM-DS
Coprococcus	IL-6	Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	DM-DS
Coprococcus	IL-6	Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	DM-DS
Oscillospira	IL-6	Oscillospira+JAK-STAT signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.62	0.52	no	no	no	no	no	no	DM-DS
Oscillospira	IL-6	Oscillospira-Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.62	0.52	no	no	no	no	no	no	DM-DS
Oscillospira	IL-6	Oscillospira+Platinum drug resistance-IL-6	Indirect	Genus	serum_cytokines	0.62	0.52	no	no	no	no	no	no	DM-DS
Oscillospira	IL-6	Oscillospira+Progesterone-mediated oocyte maturation-IL-6	Indirect	Genus	serum_cytokines	0.62	0.52	no	no	no	no	no	no	DM-DS
Oscillospira	IL-6	Oscillospira-Rap1 signaling pathway+IL-6	Indirect	Genus	serum_cytokines	0.62	0.52	no	no	no	no	no	no	DM-DS
Oscillospira	IL-6	Oscillospira+Spliceosome-IL-6	Indirect	Genus	serum_cytokines	0.62	0.52	no	no	no	no	no	no	DM-DS
Oscillospira	IL-6	Oscillospira+T cell receptor signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.62	0.52	no	no	no	no	no	no	DM-DS
Oscillospira	IL-6	Oscillospira+MAPK signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.62	0.52	no	no	no	no	no	no	DM-DS
Oscillospira	IL-6	Oscillospira-Platelet activation+IL-6	Indirect	Genus	serum_cytokines	0.62	0.52	no	no	no	no	no	no	DM-DS
Oscillospira	IL-6	Oscillospira+FoxO signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.62	0.52	no	no	no	no	no	no	DM-DS
Oscillospira	IL-6	Oscillospira-Focal adhesion+IL-6	Indirect	Genus	serum_cytokines	0.62	0.52	no	no	no	no	no	no	DM-DS
HCA+blood	IL-6	HCA+blood+UDCA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.544	0.52	no	no	no	no	no	no	DM-DS
iso-LCA+stool	IL-6	iso-LCA+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	DM-DS
DCA+blood	IL-6	DCA+blood+nutriCA+blood+UDCA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.122	0.52	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-6	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.33	0.52	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-6	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-DMG+blood-Hippuric acid+urine-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.33	0.52	no	no	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-6	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-6"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.52	up	up	no	no	no	no	DM-DS
nutriCA+blood	IL-6	nutriCA+blood+UDCA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.726	0.52	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IL-6	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.304	0.52	no	no	no	no	no	no	DM-DS
TCA+stool	IL-6	TCA+stool+16:0/18:2-PI+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-DS
HDCA+stool	IL-6	HDCA+stool+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	DM-DS
HDCA+stool	IL-6	HDCA+stool+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira+Vibrio cholerae infection+IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira+Carbon metabolism+IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira+Adherens junction+IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira-p53 signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira+Platelet activation+IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira+Bacterial invasion of epithelial cells+IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira-Progesterone-mediated oocyte maturation-IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira-Platinum drug resistance-IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira-T cell receptor signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira+Regulation of actin cytoskeleton+IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira+Rap1 signaling pathway+IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira-Spliceosome-IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira-Hippuric acid+urine-IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira-Signaling pathways regulating pluripotency of stem cells-IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira+Tight junction+IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira+Leukocyte transendothelial migration+IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira-FoxO signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira-ErbB signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira+Oxytocin signaling pathway+IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira-JAK-STAT signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira-Non-small cell lung cancer-IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira+Focal adhesion+IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Lachnospira	IL-6	Lachnospira+Fluid shear stress and atherosclerosis+IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-6	Fusobacterium-Intestinal immune network for IgA production-Progesterone-mediated oocyte maturation-IL-6	Indirect	Genus	serum_cytokines	0.628	0.52	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-6	Fusobacterium-Intestinal immune network for IgA production+Bacterial invasion of epithelial cells+IL-6	Indirect	Genus	serum_cytokines	0.628	0.52	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-6	Fusobacterium-Intestinal immune network for IgA production+Leishmaniasis+IL-6	Indirect	Genus	serum_cytokines	0.628	0.52	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-6	Fusobacterium-Intestinal immune network for IgA production+Asthma+IL-6	Indirect	Genus	serum_cytokines	0.628	0.52	no	no	no	no	no	no	DM-DS
GCDCA+stool	IL-6	GCDCA+stool+16:0/16:1-PC+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IL-6	GCDCA+stool+18:1/16:0-PC+blood-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IL-6	GCDCA+stool+16:0/18:2-PC+blood-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IL-6	GCDCA+stool-L-Phenylalanine+stool-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IL-6	GCDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IL-6	GCDCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IL-6	GCDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IL-6	GCDCA+stool+16:0/18:2-PC+blood-16:0/20:4-PI+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IL-6	GCDCA+stool+16:0/16:1-PC+blood+16:0/18:2-PI+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IL-6	GCDCA+stool+16:1/18:2-PG+blood+18:0/18:2-PI+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool+Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool+Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:1-PC+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-nutriCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:0-PC+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-nutriCA+stool-13-HODE+blood-16:0/20:4-PI+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/22:6-PA+blood-P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-nutriCA+stool-AA+blood+L-2-Aminobutyric acid+blood+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool+Kynurenic acid+stool+L-Tyrosine+stool-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool+Kynurenic acid+stool+L-Phenylalanine+stool-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-nutriCA+stool-13-HODE+blood-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-DS
Odoribacter	IL-6	Odoribacter+Pathogenic Escherichia coli infection+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	DM-DS
Odoribacter	IL-6	Odoribacter+Antigen processing and presentation+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	DM-DS
Odoribacter	IL-6	Odoribacter+Leishmaniasis+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	DM-DS
Odoribacter	IL-6	Odoribacter-Chemical carcinogenesis - receptor activation-IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	DM-DS
Odoribacter	IL-6	Odoribacter+Carbon metabolism+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	DM-DS
Actinomyces	IL-6	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.621	0.52	no	no	no	no	no	no	DM-DS
Actinomyces	IL-6	Actinomyces+Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.621	0.52	no	no	no	no	no	no	DM-DS
Actinomyces	IL-6	Actinomyces+Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.621	0.52	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IL-6	Isobutyric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.408	0.52	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IL-6	Isobutyric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.408	0.52	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IL-6	Isobutyric acid+stool+L-Phenylalanine+stool-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_scfa	serum_cytokines	0.408	0.52	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	IL-6	"2-hydroxyphenylacetic acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-6"	Indirect	urine_cometabolism	serum_cytokines	0.763	0.52	no	no	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-6	Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.037	0.52	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-6	Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.037	0.52	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-6	Kynurenic acid+stool+L-Tyrosine+stool-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.037	0.52	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-6	Kynurenic acid+stool+L-Phenylalanine+stool-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.037	0.52	dn	dn	no	no	no	no	DM-DS
Caproic acid+stool	IL-6	Caproic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.882	0.52	no	no	no	no	no	no	DM-DS
Caproic acid+stool	IL-6	Caproic acid+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.882	0.52	no	no	no	no	no	no	DM-DS
Eggerthella	IL-6	Eggerthella+Phosphatidylinositol signaling system-IL-6	Indirect	Genus	serum_cytokines	0.912	0.52	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-6	Anaerotruncus-Ruminococcus-Alcoholism-Gastric cancer-IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-6	Anaerotruncus-Ruminococcus-Alcoholism+Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-6	Anaerotruncus-Ruminococcus-Serotonergic synapse-Spinocerebellar ataxia-IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-6	Anaerotruncus-Ruminococcus-Serotonergic synapse-Pancreatic cancer-IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	DM-DS
Anaerostipes	IL-6	Anaerostipes-IL-6	Direct	Genus	serum_cytokines	0.568	0.52	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-6	TUDCA+stool-14:0/18:2-PC+blood-Creatinine+blood+DMG+blood-Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.241	0.52	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-6	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood+DMG+blood-Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.241	0.52	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-6	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood-DMG+blood-Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.241	0.52	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-6	TUDCA+stool-14:0/18:2-PC+blood+14:0/20:4-PC+blood+18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.241	0.52	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-6	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.241	0.52	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-6	TUDCA+stool+9-HODE+blood+AA+blood+L-2-Aminobutyric acid+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.241	0.52	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-6	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-L-2-Aminobutyric acid+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.241	0.52	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-6	TUDCA+stool-14:0/18:2-PC+blood+24:0+blood-P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.241	0.52	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-6	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+L-Citrulline+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.241	0.52	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-6	TUDCA+stool-d18:1-14:0-SM+blood-L-Asparagine+blood+L-Citrulline+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.241	0.52	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-6	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood-UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.241	0.52	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-6	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.241	0.52	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IL-6	Isovaleric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.343	0.52	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IL-6	Isovaleric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.343	0.52	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IL-6	Isovaleric acid+stool+L-Phenylalanine+stool-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_scfa	serum_cytokines	0.343	0.52	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-6	Paraprevotella-IL-17 signaling pathway+IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-6	Paraprevotella+Ribosome biogenesis in eukaryotes-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-6	Paraprevotella+Cell cycle-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	IL-6	¦Ø-MCA+stool-L-Tyrosine+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.919	0.52	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	IL-6	¦Ø-MCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.919	0.52	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	IL-6	¦Ø-MCA+stool-L-Tyrosine+stool-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.919	0.52	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	IL-6	¦Ø-MCA+stool-L-Phenylalanine+stool-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.919	0.52	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	IL-6	¦Ø-MCA+stool-L-Tryptophan+stool-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.919	0.52	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-6	Phenylacetic acid+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.785	0.52	no	no	no	no	no	no	DM-DS
Gemmiger	IL-6	Gemmiger+Signaling pathways regulating pluripotency of stem cells-IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	DM-DS
Gemmiger	IL-6	Gemmiger+Pathways in cancer-IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	DM-DS
Gemmiger	IL-6	Gemmiger+ErbB signaling pathway-IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	DM-DS
Gemmiger	IL-6	Gemmiger+Gastric cancer-IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	DM-DS
GDCA+stool	IL-6	GDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-DS
GDCA+stool	IL-6	GDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-DS
GDCA+stool	IL-6	"GDCA+stool+L-Lysine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-6"	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-DS
Methanobrevibacter	IL-6	Methanobrevibacter-Alcoholism-Gastric cancer-IL-6	Indirect	Genus	serum_cytokines	0.629	0.52	no	no	no	no	no	no	DM-DS
Methanobrevibacter	IL-6	Methanobrevibacter-Alcoholism+Systemic lupus erythematosus+IL-6	Indirect	Genus	serum_cytokines	0.629	0.52	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IL-6	L-Tyrosine+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.44	0.52	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IL-6	L-Tyrosine+stool-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.44	0.52	no	no	no	no	no	no	DM-DS
CDCA+stool	IL-6	CDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.663	0.52	no	no	no	no	no	no	DM-DS
CDCA+stool	IL-6	CDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.663	0.52	no	no	no	no	no	no	DM-DS
CA+stool	IL-6	CA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.827	0.52	no	no	no	no	no	no	DM-DS
HDCA+blood	IL-6	HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.483	0.52	no	no	no	no	no	no	DM-DS
UDCA+stool	IL-6	UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.266	0.52	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-6	TDCA+stool-12-ketoDCA+blood-16:0/20:4-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.963	0.52	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-6	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.963	0.52	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-6	TDCA+stool-12-ketoDCA+blood-18:1/16:0-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.963	0.52	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-6	TDCA+stool-12-ketoDCA+blood-18:1/16:1-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.963	0.52	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-6	TDCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.963	0.52	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-6	TDCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.963	0.52	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-6	TDCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.963	0.52	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-6	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.963	0.52	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-6	TDCA+stool-12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.963	0.52	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-6	TDCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.963	0.52	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-6	TDCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.963	0.52	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-6	TDCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.963	0.52	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-6	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.963	0.52	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-6	TDCA+stool-HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.963	0.52	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-6	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.963	0.52	no	no	no	no	no	no	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	IL-6	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2+IL-6	Indirect	urine_cometabolism	serum_cytokines	0.973	0.52	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-6	Desulfovibrio+Antigen processing and presentation+IL-6	Indirect	Genus	serum_cytokines	0.27	0.52	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-6	nutriCA+stool+18:0/22:6-PA+blood-P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.481	0.52	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-6	nutriCA+stool+18:0/18:1-PC+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.481	0.52	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-6	nutriCA+stool+18:0/18:0-PC+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.481	0.52	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-6	nutriCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.481	0.52	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-6	nutriCA+stool-13-HODE+blood-16:0/20:4-PI+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.481	0.52	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-6	nutriCA+stool-AA+blood+L-2-Aminobutyric acid+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.481	0.52	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-6	nutriCA+stool+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.481	0.52	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-6	nutriCA+stool-13-HODE+blood-18:3n6+blood+Hippuric acid+urine-IL-6	Indirect	stool_bileacids	serum_cytokines	0.481	0.52	no	no	no	no	no	no	DM-DS
Bilophila	IL-6	Bilophila+Desulfovibrio+Antigen processing and presentation+IL-6	Indirect	Genus	serum_cytokines	0.528	0.52	no	no	no	no	no	no	DM-DS
GDCA+blood	IL-6	GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.632	0.52	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	IL-6	P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	urine_cometabolism	serum_cytokines	0.436	0.52	no	no	no	no	no	no	DM-DS
acetic acid C2+blood	IL-6	acetic acid C2+blood+d18:1-20:1-SM+blood-GUDCA+blood+UDCA+blood+Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.000193	0.52	up	dn	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	IL-6	isovaleric acid iso-C5+blood+PUFA+blood+SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.117	0.52	no	no	no	no	no	no	DM-DS
Clostridium	IL-6	Clostridium+IL-6	Direct	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-18:1/18:1-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-16:0/18:1-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-18:1/18:0-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-18:0/18:1-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-16:0/20:4-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-18:1/16:1-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-18:1/16:0-PE+blood-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-6	Butyricicoccus-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6	Indirect	Genus	serum_cytokines	0.852	0.52	no	no	no	no	no	no	DM-DS
Blautia	IL-13	Blautia+Dorea-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	1.36E-05	0.00264	up	dn	dn	up	up	no	DM-DS
Parabacteroides	IL-13	Parabacteroides-16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	4.19E-05	0.00264	no	up	up	up	up	no	DM-DS
Dorea	IL-13	Dorea-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	DM-DS
Faecalibacterium	IL-13	Faecalibacterium-Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0039	0.00264	no	dn	dn	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Transcriptional misregulation in cancer-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+RNA transport+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+Oocyte meiosis+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Prolactin signaling pathway-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+Apelin signaling pathway+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Phospholipase D signaling pathway-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Amoebiasis-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Chagas disease-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Acute myeloid leukemia-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+Glycolysis / Gluconeogenesis+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+Long-term potentiation+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Prolactin signaling pathway-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Relaxin signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+Oocyte meiosis+Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-cAMP signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Prolactin signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Amoebiasis-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Chagas disease-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Chronic myeloid leukemia-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Acute myeloid leukemia-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+Longevity regulating pathway - multiple species+Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+Long-term potentiation+Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Long-term depression-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Pathways in cancer-16:0/20:4-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+Parabacteroides-16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Amoebiasis+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+16:1/16:1-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+16:0/22:6-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+20:3/18:0-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+18:0/20:4-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+Apelin signaling pathway-IL-17 signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Phospholipase D signaling pathway+IL-17 signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Pathways in cancer+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+16:0/20:5-PC+blood-L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+Glycolysis / Gluconeogenesis-p53 signaling pathway+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Transcriptional misregulation in cancer-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Pathways in cancer-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Chronic myeloid leukemia-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Choline metabolism in cancer-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-MicroRNAs in cancer-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	"Bacteroides-Growth hormone synthesis, secretion and action-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13"	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+Glycolysis / Gluconeogenesis+Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-16:1/18:2-PG+blood+18:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+Long-term potentiation-18:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Long-term depression+18:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+Glycolysis / Gluconeogenesis+Leukocyte transendothelial migration-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+Glycolysis / Gluconeogenesis+Platelet activation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+RNA transport-Neutrophil extracellular trap formation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+Apelin signaling pathway-Neutrophil extracellular trap formation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides-Phospholipase D signaling pathway+Neutrophil extracellular trap formation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+RNA transport+Measles+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+Legionellosis+Measles+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-13	Bacteroides+Leishmaniasis+Measles+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-DS
Propionic acid+stool	IL-13	Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.0436	0.00264	dn	no	up	up	up	no	DM-DS
[Ruminococcus]	IL-13	[Ruminococcus]-Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0679	0.00264	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-13	[Ruminococcus]+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0679	0.00264	no	no	dn	up	up	no	DM-DS
GUDCA+blood	IL-13	GUDCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00264	no	no	dn	up	up	no	DM-DS
UDCA+blood	IL-13	UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.0939	0.00264	no	no	dn	up	up	no	DM-DS
Acetic acid+stool	IL-13	Acetic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.0656	0.00264	dn	no	no	up	up	no	DM-DS
Alistipes	IL-13	Alistipes-Platelet activation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	DM-DS
Alistipes	IL-13	Alistipes-Oxytocin signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	DM-DS
Alistipes	IL-13	Alistipes-Rap1 signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	DM-DS
Butyricimonas	IL-13	Butyricimonas-L-Asparagine+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.17	0.00264	no	no	no	up	up	no	DM-DS
Butyricimonas	IL-13	Butyricimonas-iso-DCA+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.17	0.00264	no	no	no	up	up	no	DM-DS
Butyricimonas	IL-13	Butyricimonas-Butyric acid+stool+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.17	0.00264	no	no	no	up	up	no	DM-DS
Butyricimonas	IL-13	Butyricimonas-Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.17	0.00264	no	no	no	up	up	no	DM-DS
Collinsella	IL-13	Collinsella+Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-DS
Collinsella	IL-13	Collinsella-Renin secretion+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-DS
Collinsella	IL-13	Collinsella-Inflammatory mediator regulation of TRP channels+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-DS
Collinsella	IL-13	Collinsella-Endocrine and other factor-regulated calcium reabsorption+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-DS
Collinsella	IL-13	Collinsella-GnRH signaling pathway-Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-DS
Collinsella	IL-13	Collinsella-Renin secretion-Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-DS
Collinsella	IL-13	Collinsella-Endocrine and other factor-regulated calcium reabsorption-Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-DS
Collinsella	IL-13	Collinsella-Inflammatory mediator regulation of TRP channels-Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-DS
Collinsella	IL-13	Collinsella-GnRH signaling pathway+HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-DS
Collinsella	IL-13	Collinsella-Endocrine and other factor-regulated calcium reabsorption+HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Osteoclast differentiation+Neutrophil extracellular trap formation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Cellular senescence+Neutrophil extracellular trap formation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Apoptosis+Neutrophil extracellular trap formation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Osteoclast differentiation+IL-17 signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Cellular senescence+IL-17 signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Apoptosis+IL-17 signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+NF-kappa B signaling pathway+IL-17 signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Toll-like receptor signaling pathway+IL-17 signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+RIG-I-like receptor signaling pathway+IL-17 signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+C-type lectin receptor signaling pathway+IL-17 signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Dopaminergic synapse-Measles+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Hepatitis C+Measles+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Circadian entrainment-Measles+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Th17 cell differentiation+Measles+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Apoptosis+18:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Viral carcinogenesis-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Glucagon signaling pathway+HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Osteoclast differentiation-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Dopaminergic synapse+HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Cellular senescence-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Human papillomavirus infection-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Apoptosis-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Amphetamine addiction+HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-GnRH signaling pathway+HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Aldosterone synthesis and secretion+HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Fc epsilon RI signaling pathway-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Prolactin signaling pathway-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Glucagon signaling pathway+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Aldosterone synthesis and secretion+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Viral carcinogenesis-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Acute myeloid leukemia-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Cellular senescence-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Human papillomavirus infection-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Apoptosis-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Neurotrophin signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Chronic myeloid leukemia-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Toll-like receptor signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Fc epsilon RI signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Prostate cancer-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+C-type lectin receptor signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Prolactin signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+TNF signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+B cell receptor signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+NF-kappa B signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Insulin resistance-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Circadian entrainment+Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Chronic myeloid leukemia-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+RIG-I-like receptor signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Prostate cancer-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+NF-kappa B signaling pathway-Oxytocin signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Circadian entrainment+Oxytocin signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+RIG-I-like receptor signaling pathway-Oxytocin signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+TNF signaling pathway-Oxytocin signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+NF-kappa B signaling pathway-Platelet activation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Viral carcinogenesis+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Glucagon signaling pathway-Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Osteoclast differentiation+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Inflammatory mediator regulation of TRP channels-Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Cellular senescence+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Human papillomavirus infection+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Apoptosis+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Amphetamine addiction-Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Toll-like receptor signaling pathway+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-GnRH signaling pathway-Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Aldosterone synthesis and secretion-Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Fc epsilon RI signaling pathway+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+C-type lectin receptor signaling pathway+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+B cell receptor signaling pathway+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Glucagon signaling pathway+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Osteoclast differentiation-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Inflammatory mediator regulation of TRP channels+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Acute myeloid leukemia-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Apoptosis-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+NF-kappa B signaling pathway-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Amphetamine addiction+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Toll-like receptor signaling pathway-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+RIG-I-like receptor signaling pathway-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina-Aldosterone synthesis and secretion+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Fc epsilon RI signaling pathway-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+C-type lectin receptor signaling pathway-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+Prolactin signaling pathway-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Sarcina	IL-13	Sarcina+B cell receptor signaling pathway-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
Methanosphaera	IL-13	Methanosphaera-Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0703	0.00264	no	no	no	up	up	no	DM-DS
iso-DCA+stool	IL-13	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.155	0.00264	no	no	no	up	up	no	DM-DS
LCA+stool	IL-13	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.314	0.00264	no	no	no	up	up	no	DM-DS
Akkermansia	IL-13	Akkermansia+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-DS
Bifidobacterium	IL-13	Bifidobacterium+Leukocyte transendothelial migration-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.105	0.00264	no	dn	no	up	up	no	DM-DS
Ruminococcus	IL-13	"Ruminococcus-18:2n6c+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF+IL-13"	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	DM-DS
Ruminococcus	IL-13	Ruminococcus-Alcoholism+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	DM-DS
Ruminococcus	IL-13	Ruminococcus-Alcoholism-Measles+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	DM-DS
Ruminococcus	IL-13	Ruminococcus-Serotonergic synapse-Measles+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	DM-DS
Ruminococcus	IL-13	Ruminococcus-20:4-LPC+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	DM-DS
Ruminococcus	IL-13	Ruminococcus-EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	DM-DS
Ruminococcus	IL-13	Ruminococcus+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	DM-DS
Ruminococcus	IL-13	Ruminococcus-18:3n3+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	DM-DS
Ruminococcus	IL-13	Ruminococcus+18:0/18:0-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	DM-DS
GCDCA+blood	IL-13	GCDCA+blood+GUDCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.31	0.00264	no	no	no	up	up	no	DM-DS
GCDCA+blood	IL-13	GCDCA+blood+HCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.31	0.00264	no	no	no	up	up	no	DM-DS
ACA+blood	IL-13	ACA+blood+EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.338	0.00264	no	no	no	up	up	no	DM-DS
DCA+stool	IL-13	DCA+stool+HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.195	0.00264	no	no	no	up	up	no	DM-DS
Butyric acid+stool	IL-13	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.102	0.00264	dn	no	no	up	up	no	DM-DS
Butyric acid+stool	IL-13	Butyric acid+stool+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.102	0.00264	dn	no	no	up	up	no	DM-DS
4-hydroxybenzoic acid+stool	IL-13	4-hydroxybenzoic acid+stool-DCA+stool+HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.00264	no	dn	no	up	up	no	DM-DS
Turicibacter	IL-13	Turicibacter+Desulfovibrio+Antigen processing and presentation+Leukocyte transendothelial migration-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.269	0.00264	no	no	no	up	up	no	DM-DS
Turicibacter	IL-13	Turicibacter+Desulfovibrio+Antigen processing and presentation-Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.269	0.00264	no	no	no	up	up	no	DM-DS
Turicibacter	IL-13	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.269	0.00264	no	no	no	up	up	no	DM-DS
Turicibacter	IL-13	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.269	0.00264	no	no	no	up	up	no	DM-DS
Turicibacter	IL-13	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.269	0.00264	no	no	no	up	up	no	DM-DS
Turicibacter	IL-13	Turicibacter+Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.269	0.00264	no	no	no	up	up	no	DM-DS
Turicibacter	IL-13	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.269	0.00264	no	no	no	up	up	no	DM-DS
Turicibacter	IL-13	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.269	0.00264	no	no	no	up	up	no	DM-DS
Turicibacter	IL-13	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.269	0.00264	no	no	no	up	up	no	DM-DS
Turicibacter	IL-13	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.269	0.00264	no	no	no	up	up	no	DM-DS
Turicibacter	IL-13	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.269	0.00264	no	no	no	up	up	no	DM-DS
Turicibacter	IL-13	Turicibacter+Desulfovibrio+Antigen processing and presentation-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.269	0.00264	no	no	no	up	up	no	DM-DS
Turicibacter	IL-13	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.269	0.00264	no	no	no	up	up	no	DM-DS
GCA+blood	IL-13	GCA+blood+HCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.16	0.00264	no	no	no	up	up	no	DM-DS
ACA+stool	IL-13	ACA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.417	0.00264	no	no	no	up	up	no	DM-DS
CDCA+blood	IL-13	CDCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.506	0.00264	no	no	no	up	up	no	DM-DS
capric acid C6+blood	IL-13	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.433	0.00264	no	no	no	up	up	no	DM-DS
Prevotella	IL-13	Prevotella-Measles+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	DM-DS
iso-DCA+blood	IL-13	iso-DCA+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.38	0.00264	no	no	no	up	up	no	DM-DS
HCA+stool	IL-13	HCA+stool-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.155	0.00264	no	no	no	up	up	no	DM-DS
Roseburia	IL-13	Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.495	0.00264	no	no	no	up	up	no	DM-DS
12-ketoDCA+stool	IL-13	12-ketoDCA+stool+HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.505	0.00264	no	no	no	up	up	no	DM-DS
GLCA+blood	IL-13	GLCA+blood-SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.319	0.00264	no	no	no	up	up	no	DM-DS
L-Tryptophan+stool	IL-13	L-Tryptophan+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00264	no	no	no	up	up	no	DM-DS
CA+blood	IL-13	CA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.606	0.00264	no	no	no	up	up	no	DM-DS
GUDCA+stool	IL-13	GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0085	0.00264	no	dn	no	up	up	no	DM-DS
L-Phenylalanine+stool	IL-13	L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool-GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool-HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool-Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool+GCDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool+GDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool+DPA+blood-nutriCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool+GCDCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool-Isovaleric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool-Isobutyric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool+GCDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool+UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool+GDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool-iso-LCA+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool+GCDCA+stool+16:0/16:1-PC+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool-12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool+GCDCA+stool+16:1/18:2-PG+blood+18:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	GCA+stool+GCDCA+stool+16:0/18:2-PC+blood-16:0/20:4-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
GCA+stool	IL-13	"GCA+stool+GDCA+stool+L-Lysine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF+IL-13"	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-DS
Coprococcus	IL-13	Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	DM-DS
Coprococcus	IL-13	Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	DM-DS
Coprococcus	IL-13	Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	DM-DS
Oscillospira	IL-13	Oscillospira+Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.62	0.00264	no	no	no	up	up	no	DM-DS
Oscillospira	IL-13	Oscillospira-Rap1 signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.62	0.00264	no	no	no	up	up	no	DM-DS
Oscillospira	IL-13	Oscillospira+Spliceosome+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.62	0.00264	no	no	no	up	up	no	DM-DS
Oscillospira	IL-13	Oscillospira-Platelet activation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.62	0.00264	no	no	no	up	up	no	DM-DS
HCA+blood	IL-13	HCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.544	0.00264	no	no	no	up	up	no	DM-DS
iso-LCA+stool	IL-13	iso-LCA+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	DM-DS
DCA+blood	IL-13	DCA+blood+nutriCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.122	0.00264	no	no	no	up	up	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-13	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00264	no	no	no	up	up	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-13	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF+IL-13"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.00264	up	up	no	up	up	no	DM-DS
nutriCA+blood	IL-13	nutriCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.726	0.00264	no	no	no	up	up	no	DM-DS
Indole-3-Acetic acid+stool	IL-13	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00264	no	no	no	up	up	no	DM-DS
TCA+stool	IL-13	TCA+stool+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-DS
HDCA+stool	IL-13	HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	DM-DS
Lachnospira	IL-13	Lachnospira-p53 signaling pathway+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.279	0.00264	no	no	no	up	up	no	DM-DS
Lachnospira	IL-13	Lachnospira+Platelet activation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.279	0.00264	no	no	no	up	up	no	DM-DS
Lachnospira	IL-13	Lachnospira-Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.279	0.00264	no	no	no	up	up	no	DM-DS
Lachnospira	IL-13	Lachnospira+Rap1 signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.279	0.00264	no	no	no	up	up	no	DM-DS
Lachnospira	IL-13	Lachnospira-Spliceosome+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.279	0.00264	no	no	no	up	up	no	DM-DS
Lachnospira	IL-13	Lachnospira+Leukocyte transendothelial migration-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.279	0.00264	no	no	no	up	up	no	DM-DS
Lachnospira	IL-13	Lachnospira+Oxytocin signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.279	0.00264	no	no	no	up	up	no	DM-DS
Lachnospira	IL-13	Lachnospira+Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.279	0.00264	no	no	no	up	up	no	DM-DS
Fusobacterium	IL-13	Fusobacterium-Intestinal immune network for IgA production-L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.628	0.00264	no	no	no	up	up	no	DM-DS
Fusobacterium	IL-13	Fusobacterium-Intestinal immune network for IgA production-Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.628	0.00264	no	no	no	up	up	no	DM-DS
Fusobacterium	IL-13	Fusobacterium-Intestinal immune network for IgA production-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.628	0.00264	no	no	no	up	up	no	DM-DS
Fusobacterium	IL-13	Fusobacterium-18:0/18:0-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.628	0.00264	no	no	no	up	up	no	DM-DS
Fusobacterium	IL-13	Fusobacterium-16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.628	0.00264	no	no	no	up	up	no	DM-DS
Fusobacterium	IL-13	Fusobacterium-18:0/18:1-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.628	0.00264	no	no	no	up	up	no	DM-DS
Fusobacterium	IL-13	Fusobacterium-GUDCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.628	0.00264	no	no	no	up	up	no	DM-DS
Fusobacterium	IL-13	Fusobacterium-16:0/18:2-PC+blood-16:0/20:4-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.628	0.00264	no	no	no	up	up	no	DM-DS
GCDCA+stool	IL-13	GCDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	DM-DS
GCDCA+stool	IL-13	GCDCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	DM-DS
GCDCA+stool	IL-13	GCDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	DM-DS
GCDCA+stool	IL-13	GCDCA+stool+16:0/18:2-PC+blood-16:0/20:4-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	DM-DS
GCDCA+stool	IL-13	GCDCA+stool+16:0/16:1-PC+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	DM-DS
GCDCA+stool	IL-13	GCDCA+stool+16:1/18:2-PG+blood+18:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool+Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool+Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:1-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-nutriCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:0-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-nutriCA+stool-13-HODE+blood-16:0/20:4-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/22:6-PA+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-nutriCA+stool-AA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-DS
Odoribacter	IL-13	Odoribacter-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	DM-DS
Odoribacter	IL-13	Odoribacter+Neuroactive ligand-receptor interaction-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	DM-DS
Odoribacter	IL-13	Odoribacter+16:0/20:4-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	DM-DS
Actinomyces	IL-13	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.621	0.00264	no	no	no	up	up	no	DM-DS
Actinomyces	IL-13	Actinomyces+Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.621	0.00264	no	no	no	up	up	no	DM-DS
Actinomyces	IL-13	Actinomyces+Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.621	0.00264	no	no	no	up	up	no	DM-DS
Isobutyric acid+stool	IL-13	Isobutyric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.408	0.00264	no	no	no	up	up	no	DM-DS
Isobutyric acid+stool	IL-13	Isobutyric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.408	0.00264	no	no	no	up	up	no	DM-DS
2-hydroxyphenylacetic acid+urine	IL-13	"2-hydroxyphenylacetic acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF+IL-13"	Indirect	urine_cometabolism	serum_cytokines	0.763	0.00264	no	no	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-13	Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00264	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-13	Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00264	dn	dn	no	up	up	no	DM-DS
Caproic acid+stool	IL-13	Caproic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.882	0.00264	no	no	no	up	up	no	DM-DS
Caproic acid+stool	IL-13	Caproic acid+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.882	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella+AMPK signaling pathway-Neutrophil extracellular trap formation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella+Phosphatidylinositol signaling system-Neutrophil extracellular trap formation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella+AMPK signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella-Yersinia infection+Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella-Influenza A+Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella-Yersinia infection-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella+Phosphatidylinositol signaling system+Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella-Influenza A-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella-Yersinia infection-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella-Influenza A-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella-Yersinia infection-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella+Phosphatidylinositol signaling system+Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella+AMPK signaling pathway-IL-17 signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella+Phosphatidylinositol signaling system-IL-17 signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella+AMPK signaling pathway+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella+Phosphatidylinositol signaling system-Lysosome-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella+Phosphatidylinositol signaling system+p53 signaling pathway+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella+AMPK signaling pathway-Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella-Yersinia infection+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella+Phosphatidylinositol signaling system-Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella-Influenza A+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella-Yersinia infection+18:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Eggerthella	IL-13	Eggerthella+Phosphatidylinositol signaling system-18:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	DM-DS
Anaerotruncus	IL-13	"Anaerotruncus-Ruminococcus-18:2n6c+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF+IL-13"	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	DM-DS
Anaerotruncus	IL-13	Anaerotruncus-Ruminococcus-Alcoholism+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	DM-DS
Anaerotruncus	IL-13	Anaerotruncus-Ruminococcus-Alcoholism-Measles+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	DM-DS
Anaerotruncus	IL-13	Anaerotruncus-Ruminococcus-Serotonergic synapse-Measles+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	DM-DS
Anaerotruncus	IL-13	Anaerotruncus-Ruminococcus-20:4-LPC+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	DM-DS
Anaerotruncus	IL-13	Anaerotruncus-Ruminococcus-EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	DM-DS
Anaerotruncus	IL-13	Anaerotruncus-Ruminococcus+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	DM-DS
Anaerotruncus	IL-13	Anaerotruncus-Ruminococcus-18:3n3+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	DM-DS
Anaerotruncus	IL-13	Anaerotruncus-Ruminococcus+18:0/18:0-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	DM-DS
Anaerostipes	IL-13	Anaerostipes+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.568	0.00264	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-13	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.241	0.00264	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-13	TUDCA+stool+9-HODE+blood+AA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.241	0.00264	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-13	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.241	0.00264	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-13	TUDCA+stool-14:0/18:2-PC+blood+24:0+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.241	0.00264	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-13	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.241	0.00264	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-13	TUDCA+stool-d18:1-14:0-SM+blood-L-Asparagine+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.241	0.00264	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-13	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.241	0.00264	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-13	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.241	0.00264	no	no	no	up	up	no	DM-DS
Isovaleric acid+stool	IL-13	Isovaleric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.343	0.00264	no	no	no	up	up	no	DM-DS
Isovaleric acid+stool	IL-13	Isovaleric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.343	0.00264	no	no	no	up	up	no	DM-DS
Paraprevotella	IL-13	Paraprevotella-IL-17 signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-DS
¦Ø-MCA+stool	IL-13	¦Ø-MCA+stool-L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.919	0.00264	no	no	no	up	up	no	DM-DS
¦Ø-MCA+stool	IL-13	¦Ø-MCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.919	0.00264	no	no	no	up	up	no	DM-DS
Phenylacetic acid+stool	IL-13	Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.785	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+PI3K-Akt signaling pathway+Measles+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	"Gemmiger-12,13-EPOME+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13"	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Platelet activation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+ErbB signaling pathway-Platelet activation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+ErbB signaling pathway+p53 signaling pathway+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+ErbB signaling pathway+Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+Pathways in cancer-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+ErbB signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+Gastric cancer-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+Gastric cancer-Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+24:0+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+Pathways in cancer-16:0/20:4-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+Pathways in cancer+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Leukocyte transendothelial migration-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Neutrophil extracellular trap formation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Oxytocin signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
Gemmiger	IL-13	Gemmiger+ErbB signaling pathway-Oxytocin signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-DS
GDCA+stool	IL-13	GDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-DS
GDCA+stool	IL-13	GDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-DS
GDCA+stool	IL-13	"GDCA+stool+L-Lysine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF+IL-13"	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-DS
Methanobrevibacter	IL-13	Methanobrevibacter-Alcoholism-Measles+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.629	0.00264	no	no	no	up	up	no	DM-DS
Methanobrevibacter	IL-13	Methanobrevibacter-Alcoholism+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.629	0.00264	no	no	no	up	up	no	DM-DS
L-Tyrosine+stool	IL-13	L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00264	no	no	no	up	up	no	DM-DS
CDCA+stool	IL-13	CDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.663	0.00264	no	no	no	up	up	no	DM-DS
CDCA+stool	IL-13	CDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.663	0.00264	no	no	no	up	up	no	DM-DS
CA+stool	IL-13	CA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.827	0.00264	no	no	no	up	up	no	DM-DS
HDCA+blood	IL-13	HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.483	0.00264	no	no	no	up	up	no	DM-DS
UDCA+stool	IL-13	UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.266	0.00264	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-13	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.963	0.00264	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-13	TDCA+stool-12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.963	0.00264	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-13	TDCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.963	0.00264	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-13	TDCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.963	0.00264	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-13	TDCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.963	0.00264	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-13	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.963	0.00264	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-13	TDCA+stool-HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.963	0.00264	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-13	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.963	0.00264	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-13	Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.27	0.00264	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-13	Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.27	0.00264	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-13	Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.27	0.00264	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-13	Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.27	0.00264	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-13	Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.27	0.00264	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-13	Desulfovibrio+Antigen processing and presentation-Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.27	0.00264	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-13	Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.27	0.00264	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-13	Desulfovibrio+Antigen processing and presentation+Leukocyte transendothelial migration-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.27	0.00264	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-13	Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.27	0.00264	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-13	Desulfovibrio+Human cytomegalovirus infection-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.27	0.00264	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-13	Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.27	0.00264	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-13	Desulfovibrio+Antigen processing and presentation-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.27	0.00264	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-13	Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.27	0.00264	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-13	nutriCA+stool+18:0/22:6-PA+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.481	0.00264	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-13	nutriCA+stool+18:0/18:1-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.481	0.00264	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-13	nutriCA+stool+18:0/18:0-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.481	0.00264	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-13	nutriCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.481	0.00264	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-13	nutriCA+stool-13-HODE+blood-16:0/20:4-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.481	0.00264	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-13	nutriCA+stool-AA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.481	0.00264	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-13	nutriCA+stool+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.481	0.00264	no	no	no	up	up	no	DM-DS
Bilophila	IL-13	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.528	0.00264	no	no	no	up	up	no	DM-DS
Bilophila	IL-13	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.528	0.00264	no	no	no	up	up	no	DM-DS
Bilophila	IL-13	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.528	0.00264	no	no	no	up	up	no	DM-DS
Bilophila	IL-13	Bilophila+Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.528	0.00264	no	no	no	up	up	no	DM-DS
Bilophila	IL-13	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.528	0.00264	no	no	no	up	up	no	DM-DS
Bilophila	IL-13	Bilophila+Desulfovibrio+Antigen processing and presentation-Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.528	0.00264	no	no	no	up	up	no	DM-DS
Bilophila	IL-13	Bilophila+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.528	0.00264	no	no	no	up	up	no	DM-DS
Bilophila	IL-13	Bilophila+Desulfovibrio+Antigen processing and presentation+Leukocyte transendothelial migration-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.528	0.00264	no	no	no	up	up	no	DM-DS
Bilophila	IL-13	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.528	0.00264	no	no	no	up	up	no	DM-DS
Bilophila	IL-13	Bilophila+Desulfovibrio+Human cytomegalovirus infection-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.528	0.00264	no	no	no	up	up	no	DM-DS
Bilophila	IL-13	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.528	0.00264	no	no	no	up	up	no	DM-DS
Bilophila	IL-13	Bilophila+Desulfovibrio+Antigen processing and presentation-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.528	0.00264	no	no	no	up	up	no	DM-DS
Bilophila	IL-13	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.528	0.00264	no	no	no	up	up	no	DM-DS
GDCA+blood	IL-13	GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.632	0.00264	no	no	no	up	up	no	DM-DS
P-hydroxyhippuric acid+urine	IL-13	P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	urine_cometabolism	serum_cytokines	0.436	0.00264	no	no	no	up	up	no	DM-DS
acetic acid C2+blood	IL-13	acetic acid C2+blood+d18:1-20:1-SM+blood-GUDCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.000193	0.00264	up	dn	no	up	up	no	DM-DS
isovaleric acid iso-C5+blood	IL-13	isovaleric acid iso-C5+blood+PUFA+blood+SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.117	0.00264	no	no	no	up	up	no	DM-DS
Clostridium	IL-13	Clostridium-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-DS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	IL-13	12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.517	0.00264	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	IL-13	12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.517	0.00264	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	IL-13	12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.517	0.00264	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	IL-13	12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.517	0.00264	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	IL-13	12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.517	0.00264	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	IL-13	12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.517	0.00264	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	IL-13	12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.517	0.00264	no	no	no	up	up	no	DM-DS
Butyricicoccus	IL-13	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13"	Indirect	Genus	serum_cytokines	0.852	0.00264	no	no	no	up	up	no	DM-DS
Blautia	IL-4	Blautia+Dorea-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	DM-DS
Parabacteroides	IL-4	Parabacteroides-16:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	4.19E-05	0.858	no	up	up	no	no	no	DM-DS
Dorea	IL-4	Dorea-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.00362	0.858	up	no	dn	no	no	no	DM-DS
Faecalibacterium	IL-4	Faecalibacterium-Phenylacetic acid+stool-UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Transcriptional misregulation in cancer-UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+RNA transport+UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+Oocyte meiosis+UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Prolactin signaling pathway-UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+Apelin signaling pathway+UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Phospholipase D signaling pathway-UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Amoebiasis-UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Chagas disease-UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Acute myeloid leukemia-UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+Glycolysis / Gluconeogenesis+UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+Long-term potentiation+UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Prolactin signaling pathway-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Relaxin signaling pathway-Primary immunodeficiency+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+Oocyte meiosis+Primary immunodeficiency+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-cAMP signaling pathway-Primary immunodeficiency+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Prolactin signaling pathway-Primary immunodeficiency+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Amoebiasis-Primary immunodeficiency+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Chagas disease-Primary immunodeficiency+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Chronic myeloid leukemia-Primary immunodeficiency+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Acute myeloid leukemia-Primary immunodeficiency+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+Longevity regulating pathway - multiple species+Primary immunodeficiency+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+Long-term potentiation+Primary immunodeficiency+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Long-term depression-Primary immunodeficiency+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Pathways in cancer-16:0/20:4-PI+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+Parabacteroides-16:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Amoebiasis+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+16:1/16:1-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+16:0/22:6-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+20:3/18:0-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+18:0/20:4-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+Apelin signaling pathway-IL-17 signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Phospholipase D signaling pathway+IL-17 signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Pathways in cancer+L-Citrulline+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+16:0/20:5-PC+blood-L-Citrulline+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+Glycolysis / Gluconeogenesis-p53 signaling pathway+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Transcriptional misregulation in cancer-Fluid shear stress and atherosclerosis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Pathways in cancer-Fluid shear stress and atherosclerosis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Chronic myeloid leukemia-Fluid shear stress and atherosclerosis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Choline metabolism in cancer-Fluid shear stress and atherosclerosis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-MicroRNAs in cancer-Fluid shear stress and atherosclerosis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	"Bacteroides-Growth hormone synthesis, secretion and action-Fluid shear stress and atherosclerosis-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+Glycolysis / Gluconeogenesis+Fluid shear stress and atherosclerosis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-16:1/18:2-PG+blood+18:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+Long-term potentiation-18:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Long-term depression+18:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+Glycolysis / Gluconeogenesis+Leukocyte transendothelial migration-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+Glycolysis / Gluconeogenesis+Platelet activation-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+RNA transport-Neutrophil extracellular trap formation-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+Apelin signaling pathway-Neutrophil extracellular trap formation-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Phospholipase D signaling pathway+Neutrophil extracellular trap formation-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+RNA transport+Measles+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+Legionellosis+Measles+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+Leishmaniasis+Measles+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Relaxin signaling pathway+FGF basic+IL-17A+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-cAMP signaling pathway+FGF basic+IL-17A+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides+16:1/16:1-PC+blood-FGF basic+IL-17A+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Amoebiasis+FGF basic+IL-17A+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Chagas disease+FGF basic+IL-17A+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Chronic myeloid leukemia+FGF basic+IL-17A+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-4	Bacteroides-Acute myeloid leukemia+FGF basic+IL-17A+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-DS
Propionic acid+stool	IL-4	Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.0436	0.858	dn	no	up	no	no	no	DM-DS
[Ruminococcus]	IL-4	[Ruminococcus]-Progesterone-mediated oocyte maturation+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0679	0.858	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-4	[Ruminococcus]+16:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0679	0.858	no	no	dn	no	no	no	DM-DS
GUDCA+blood	IL-4	GUDCA+blood+UDCA+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.0766	0.858	no	no	dn	no	no	no	DM-DS
UDCA+blood	IL-4	UDCA+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.0939	0.858	no	no	dn	no	no	no	DM-DS
Acetic acid+stool	IL-4	Acetic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.0656	0.858	dn	no	no	no	no	no	DM-DS
Alistipes	IL-4	Alistipes-Platelet activation-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0114	0.858	no	up	no	no	no	no	DM-DS
Alistipes	IL-4	Alistipes-Oxytocin signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0114	0.858	no	up	no	no	no	no	DM-DS
Alistipes	IL-4	Alistipes-Rap1 signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0114	0.858	no	up	no	no	no	no	DM-DS
Butyricimonas	IL-4	Butyricimonas-L-Asparagine+blood+L-Citrulline+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.17	0.858	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-4	Butyricimonas-iso-DCA+blood+L-Citrulline+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.17	0.858	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-4	Butyricimonas-Butyric acid+stool+L-Citrulline+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.17	0.858	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-4	Butyricimonas-Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.17	0.858	no	no	no	no	no	no	DM-DS
Collinsella	IL-4	Collinsella+Roseburia+16:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-DS
Collinsella	IL-4	Collinsella-Renin secretion+UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-DS
Collinsella	IL-4	Collinsella-Inflammatory mediator regulation of TRP channels+UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-DS
Collinsella	IL-4	Collinsella-Endocrine and other factor-regulated calcium reabsorption+P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-DS
Collinsella	IL-4	Collinsella-GnRH signaling pathway-Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-DS
Collinsella	IL-4	Collinsella-Renin secretion-Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-DS
Collinsella	IL-4	Collinsella-Endocrine and other factor-regulated calcium reabsorption-Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-DS
Collinsella	IL-4	Collinsella-Inflammatory mediator regulation of TRP channels-Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-DS
Collinsella	IL-4	Collinsella-GnRH signaling pathway+HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-DS
Collinsella	IL-4	Collinsella-Endocrine and other factor-regulated calcium reabsorption+HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-DS
Sarcina	IL-4	Sarcina+FGF basic+IL-17A+IL-4	Indirect	Genus	serum_cytokines	0.0703	0.858	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-4	Methanosphaera-Roseburia+16:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0703	0.858	no	no	no	no	no	no	DM-DS
iso-DCA+stool	IL-4	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.155	0.858	no	no	no	no	no	no	DM-DS
LCA+stool	IL-4	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	DM-DS
Akkermansia	IL-4	Akkermansia+P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.23	0.858	no	no	no	no	no	no	DM-DS
Bifidobacterium	IL-4	Bifidobacterium+Leukocyte transendothelial migration-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.105	0.858	no	dn	no	no	no	no	DM-DS
Ruminococcus	IL-4	"Ruminococcus-18:2n6c+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-4	Ruminococcus-Alcoholism+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-4	Ruminococcus-Alcoholism-Measles+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-4	Ruminococcus-Serotonergic synapse-Measles+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-4	Ruminococcus-20:4-LPC+blood+L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-4	Ruminococcus-EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-4	Ruminococcus+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-4	Ruminococcus-18:3n3+blood+L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-4	Ruminococcus+18:0/18:0-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-4	Ruminococcus-n3+blood-FGF basic+IL-17A+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-4	Ruminococcus-18:3n3+blood-FGF basic+IL-17A+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-DS
GCDCA+blood	IL-4	GCDCA+blood+GUDCA+blood+UDCA+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.31	0.858	no	no	no	no	no	no	DM-DS
GCDCA+blood	IL-4	GCDCA+blood+HCA+blood+UDCA+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.31	0.858	no	no	no	no	no	no	DM-DS
ACA+blood	IL-4	ACA+blood+EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.338	0.858	no	no	no	no	no	no	DM-DS
DCA+stool	IL-4	DCA+stool+HDCA+stool+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.195	0.858	no	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-4	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.102	0.858	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-4	Butyric acid+stool+L-Citrulline+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.102	0.858	dn	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	IL-4	4-hydroxybenzoic acid+stool-DCA+stool+HDCA+stool+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.858	no	dn	no	no	no	no	DM-DS
Turicibacter	IL-4	Turicibacter+Desulfovibrio+Antigen processing and presentation+Leukocyte transendothelial migration-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.269	0.858	no	no	no	no	no	no	DM-DS
Turicibacter	IL-4	Turicibacter+Desulfovibrio+Antigen processing and presentation-Progesterone-mediated oocyte maturation+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.269	0.858	no	no	no	no	no	no	DM-DS
Turicibacter	IL-4	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.269	0.858	no	no	no	no	no	no	DM-DS
Turicibacter	IL-4	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.269	0.858	no	no	no	no	no	no	DM-DS
Turicibacter	IL-4	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.269	0.858	no	no	no	no	no	no	DM-DS
Turicibacter	IL-4	Turicibacter+Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.269	0.858	no	no	no	no	no	no	DM-DS
Turicibacter	IL-4	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.269	0.858	no	no	no	no	no	no	DM-DS
Turicibacter	IL-4	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.269	0.858	no	no	no	no	no	no	DM-DS
Turicibacter	IL-4	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.269	0.858	no	no	no	no	no	no	DM-DS
Turicibacter	IL-4	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.269	0.858	no	no	no	no	no	no	DM-DS
Turicibacter	IL-4	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.269	0.858	no	no	no	no	no	no	DM-DS
Turicibacter	IL-4	Turicibacter+Desulfovibrio+Antigen processing and presentation-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.269	0.858	no	no	no	no	no	no	DM-DS
Turicibacter	IL-4	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.269	0.858	no	no	no	no	no	no	DM-DS
GCA+blood	IL-4	GCA+blood+HCA+blood+UDCA+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.16	0.858	no	no	no	no	no	no	DM-DS
ACA+stool	IL-4	ACA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.417	0.858	no	no	no	no	no	no	DM-DS
CDCA+blood	IL-4	CDCA+blood+UDCA+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.506	0.858	no	no	no	no	no	no	DM-DS
capric acid C6+blood	IL-4	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.433	0.858	no	no	no	no	no	no	DM-DS
Prevotella	IL-4	Prevotella-Measles+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	DM-DS
iso-DCA+blood	IL-4	iso-DCA+blood+L-Citrulline+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.38	0.858	no	no	no	no	no	no	DM-DS
HCA+stool	IL-4	HCA+stool-HDCA+stool+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.155	0.858	no	no	no	no	no	no	DM-DS
Roseburia	IL-4	Roseburia+16:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.495	0.858	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	IL-4	12-ketoDCA+stool+HDCA+stool+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.505	0.858	no	no	no	no	no	no	DM-DS
GLCA+blood	IL-4	GLCA+blood-SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.319	0.858	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-4	L-Tryptophan+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.557	0.858	no	no	no	no	no	no	DM-DS
CA+blood	IL-4	CA+blood+UDCA+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.606	0.858	no	no	no	no	no	no	DM-DS
GUDCA+stool	IL-4	GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0085	0.858	no	dn	no	no	no	no	DM-DS
L-Phenylalanine+stool	IL-4	L-Phenylalanine+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.398	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool-GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool-HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool-Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool+GCDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool+GDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool+DPA+blood-nutriCA+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool+GCDCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool-Isovaleric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool-Isobutyric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool+GCDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool+UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool+GDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool-iso-LCA+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool+GCDCA+stool+16:0/16:1-PC+blood+16:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool-12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool+GCDCA+stool+16:1/18:2-PG+blood+18:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	GCA+stool+GCDCA+stool+16:0/18:2-PC+blood-16:0/20:4-PI+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
GCA+stool	IL-4	"GCA+stool+GDCA+stool+L-Lysine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-DS
Coprococcus	IL-4	Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	DM-DS
Coprococcus	IL-4	Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	DM-DS
Coprococcus	IL-4	Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	DM-DS
Oscillospira	IL-4	Oscillospira+Progesterone-mediated oocyte maturation+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.62	0.858	no	no	no	no	no	no	DM-DS
Oscillospira	IL-4	Oscillospira-Rap1 signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.62	0.858	no	no	no	no	no	no	DM-DS
Oscillospira	IL-4	Oscillospira+Spliceosome+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.62	0.858	no	no	no	no	no	no	DM-DS
Oscillospira	IL-4	Oscillospira-Platelet activation-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.62	0.858	no	no	no	no	no	no	DM-DS
HCA+blood	IL-4	HCA+blood+UDCA+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.544	0.858	no	no	no	no	no	no	DM-DS
iso-LCA+stool	IL-4	iso-LCA+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.72	0.858	no	no	no	no	no	no	DM-DS
DCA+blood	IL-4	DCA+blood+nutriCA+blood+UDCA+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.122	0.858	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-4	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.33	0.858	no	no	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-4	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.858	up	up	no	no	no	no	DM-DS
nutriCA+blood	IL-4	nutriCA+blood+UDCA+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.726	0.858	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IL-4	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.304	0.858	no	no	no	no	no	no	DM-DS
TCA+stool	IL-4	TCA+stool+16:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.458	0.858	no	no	no	no	no	no	DM-DS
HDCA+stool	IL-4	HDCA+stool+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-DS
Lachnospira	IL-4	Lachnospira-p53 signaling pathway+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.279	0.858	no	no	no	no	no	no	DM-DS
Lachnospira	IL-4	Lachnospira+Platelet activation-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.279	0.858	no	no	no	no	no	no	DM-DS
Lachnospira	IL-4	Lachnospira-Progesterone-mediated oocyte maturation+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.279	0.858	no	no	no	no	no	no	DM-DS
Lachnospira	IL-4	Lachnospira+Rap1 signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.279	0.858	no	no	no	no	no	no	DM-DS
Lachnospira	IL-4	Lachnospira-Spliceosome+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.279	0.858	no	no	no	no	no	no	DM-DS
Lachnospira	IL-4	Lachnospira+Leukocyte transendothelial migration-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.279	0.858	no	no	no	no	no	no	DM-DS
Lachnospira	IL-4	Lachnospira+Oxytocin signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.279	0.858	no	no	no	no	no	no	DM-DS
Lachnospira	IL-4	Lachnospira+Fluid shear stress and atherosclerosis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.279	0.858	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-4	Fusobacterium-Intestinal immune network for IgA production-L-Citrulline+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.628	0.858	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-4	Fusobacterium-Intestinal immune network for IgA production-Progesterone-mediated oocyte maturation+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.628	0.858	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-4	Fusobacterium-Intestinal immune network for IgA production-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.628	0.858	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-4	Fusobacterium-18:0/18:0-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.628	0.858	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-4	Fusobacterium-16:0/20:3-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.628	0.858	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-4	Fusobacterium-18:0/18:1-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.628	0.858	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-4	Fusobacterium-GUDCA+blood+UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.628	0.858	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-4	Fusobacterium-16:0/18:2-PC+blood-16:0/20:4-PI+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.628	0.858	no	no	no	no	no	no	DM-DS
GCDCA+stool	IL-4	GCDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0471	0.858	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IL-4	GCDCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0471	0.858	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IL-4	GCDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0471	0.858	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IL-4	GCDCA+stool+16:0/18:2-PC+blood-16:0/20:4-PI+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0471	0.858	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IL-4	GCDCA+stool+16:0/16:1-PC+blood+16:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0471	0.858	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IL-4	GCDCA+stool+16:1/18:2-PG+blood+18:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0471	0.858	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IL-4	GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0471	0.858	no	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:1-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-nutriCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:0-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-nutriCA+stool-13-HODE+blood-16:0/20:4-PI+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/22:6-PA+blood-P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-nutriCA+stool-AA+blood+L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-DS
Odoribacter	IL-4	Odoribacter-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.798	0.858	no	no	no	no	no	no	DM-DS
Odoribacter	IL-4	Odoribacter+Neuroactive ligand-receptor interaction-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.798	0.858	no	no	no	no	no	no	DM-DS
Odoribacter	IL-4	Odoribacter+16:0/20:4-PI+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.798	0.858	no	no	no	no	no	no	DM-DS
Actinomyces	IL-4	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.621	0.858	no	no	no	no	no	no	DM-DS
Actinomyces	IL-4	Actinomyces+Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.621	0.858	no	no	no	no	no	no	DM-DS
Actinomyces	IL-4	Actinomyces+Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.621	0.858	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IL-4	Isobutyric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.408	0.858	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IL-4	Isobutyric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.408	0.858	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	IL-4	"2-hydroxyphenylacetic acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	urine_cometabolism	serum_cytokines	0.763	0.858	no	no	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-4	Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.037	0.858	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-4	Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.037	0.858	dn	dn	no	no	no	no	DM-DS
Caproic acid+stool	IL-4	Caproic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.882	0.858	no	no	no	no	no	no	DM-DS
Caproic acid+stool	IL-4	Caproic acid+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.882	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella+AMPK signaling pathway-Neutrophil extracellular trap formation-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella+Phosphatidylinositol signaling system-Neutrophil extracellular trap formation-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella+AMPK signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella-Yersinia infection+Fluid shear stress and atherosclerosis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella-Influenza A+Fluid shear stress and atherosclerosis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella-Yersinia infection-Primary immunodeficiency+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella+Phosphatidylinositol signaling system+Primary immunodeficiency+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella-Influenza A-Primary immunodeficiency+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella-Yersinia infection-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella-Influenza A-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella-Yersinia infection-UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella+Phosphatidylinositol signaling system+Progesterone-mediated oocyte maturation+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella+AMPK signaling pathway-IL-17 signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella+Phosphatidylinositol signaling system-IL-17 signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella+AMPK signaling pathway+L-Citrulline+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella+Phosphatidylinositol signaling system-Lysosome-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella+Phosphatidylinositol signaling system+p53 signaling pathway+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella+AMPK signaling pathway-Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella-Yersinia infection+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella+Phosphatidylinositol signaling system-Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella-Influenza A+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella-Yersinia infection+18:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Eggerthella	IL-4	Eggerthella+Phosphatidylinositol signaling system-18:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-4	"Anaerotruncus-Ruminococcus-18:2n6c+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	0.904	0.858	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-4	Anaerotruncus-Ruminococcus-Alcoholism+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.904	0.858	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-4	Anaerotruncus-Ruminococcus-Alcoholism-Measles+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.904	0.858	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-4	Anaerotruncus-Ruminococcus-Serotonergic synapse-Measles+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.904	0.858	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-4	Anaerotruncus-Ruminococcus-20:4-LPC+blood+L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.904	0.858	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-4	Anaerotruncus-Ruminococcus-EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.904	0.858	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-4	Anaerotruncus-Ruminococcus+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.904	0.858	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-4	Anaerotruncus-Ruminococcus-18:3n3+blood+L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.904	0.858	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-4	Anaerotruncus-Ruminococcus+18:0/18:0-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.904	0.858	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-4	Anaerotruncus-Ruminococcus-n3+blood-FGF basic+IL-17A+IL-4	Indirect	Genus	serum_cytokines	0.904	0.858	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-4	Anaerotruncus-Ruminococcus-18:3n3+blood-FGF basic+IL-17A+IL-4	Indirect	Genus	serum_cytokines	0.904	0.858	no	no	no	no	no	no	DM-DS
Anaerostipes	IL-4	Anaerostipes+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.568	0.858	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-4	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.241	0.858	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-4	TUDCA+stool+9-HODE+blood+AA+blood+L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.241	0.858	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-4	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.241	0.858	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-4	TUDCA+stool-14:0/18:2-PC+blood+24:0+blood-P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.241	0.858	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-4	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+L-Citrulline+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.241	0.858	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-4	TUDCA+stool-d18:1-14:0-SM+blood-L-Asparagine+blood+L-Citrulline+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.241	0.858	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-4	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood-UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.241	0.858	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-4	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.241	0.858	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IL-4	Isovaleric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.343	0.858	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IL-4	Isovaleric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.343	0.858	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-4	Paraprevotella-IL-17 signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	IL-4	¦Ø-MCA+stool-L-Tyrosine+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.919	0.858	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	IL-4	¦Ø-MCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.919	0.858	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-4	Phenylacetic acid+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.785	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+PI3K-Akt signaling pathway+Measles+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	"Gemmiger-12,13-EPOME+blood+16:0/18:2-PI+blood-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Platelet activation-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+ErbB signaling pathway-Platelet activation-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+ErbB signaling pathway+p53 signaling pathway+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Progesterone-mediated oocyte maturation+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+ErbB signaling pathway+Progesterone-mediated oocyte maturation+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Fluid shear stress and atherosclerosis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+Pathways in cancer-Fluid shear stress and atherosclerosis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+ErbB signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+Gastric cancer-Fluid shear stress and atherosclerosis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+Gastric cancer-Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+24:0+blood-P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+Pathways in cancer-16:0/20:4-PI+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+Pathways in cancer+L-Citrulline+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Leukocyte transendothelial migration-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Neutrophil extracellular trap formation-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Oxytocin signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
Gemmiger	IL-4	Gemmiger+ErbB signaling pathway-Oxytocin signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-DS
GDCA+stool	IL-4	GDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.656	0.858	no	no	no	no	no	no	DM-DS
GDCA+stool	IL-4	GDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.656	0.858	no	no	no	no	no	no	DM-DS
GDCA+stool	IL-4	"GDCA+stool+L-Lysine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	stool_bileacids	serum_cytokines	0.656	0.858	no	no	no	no	no	no	DM-DS
Methanobrevibacter	IL-4	Methanobrevibacter-Alcoholism-Measles+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.629	0.858	no	no	no	no	no	no	DM-DS
Methanobrevibacter	IL-4	Methanobrevibacter-Alcoholism+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.629	0.858	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IL-4	L-Tyrosine+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.44	0.858	no	no	no	no	no	no	DM-DS
CDCA+stool	IL-4	CDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	DM-DS
CDCA+stool	IL-4	CDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	DM-DS
CDCA+stool	IL-4	CDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	DM-DS
CA+stool	IL-4	CA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	DM-DS
HDCA+blood	IL-4	HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.483	0.858	no	no	no	no	no	no	DM-DS
UDCA+stool	IL-4	UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.266	0.858	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-4	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.963	0.858	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-4	TDCA+stool-12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.963	0.858	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-4	TDCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.963	0.858	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-4	TDCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.963	0.858	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-4	TDCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.963	0.858	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-4	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.963	0.858	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-4	TDCA+stool-HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.963	0.858	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-4	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.963	0.858	no	no	no	no	no	no	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	IL-4	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A+IL-4	Indirect	urine_cometabolism	serum_cytokines	0.973	0.858	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-4	Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.27	0.858	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-4	Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.27	0.858	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-4	Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.27	0.858	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-4	Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.27	0.858	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-4	Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.27	0.858	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-4	Desulfovibrio+Antigen processing and presentation-Progesterone-mediated oocyte maturation+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.27	0.858	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-4	Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.27	0.858	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-4	Desulfovibrio+Antigen processing and presentation+Leukocyte transendothelial migration-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.27	0.858	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-4	Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.27	0.858	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-4	Desulfovibrio+Human cytomegalovirus infection-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.27	0.858	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-4	Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.27	0.858	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-4	Desulfovibrio+Antigen processing and presentation-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.27	0.858	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-4	Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.27	0.858	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-4	nutriCA+stool+18:0/22:6-PA+blood-P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.481	0.858	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-4	nutriCA+stool+18:0/18:1-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.481	0.858	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-4	nutriCA+stool+18:0/18:0-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.481	0.858	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-4	nutriCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.481	0.858	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-4	nutriCA+stool-13-HODE+blood-16:0/20:4-PI+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.481	0.858	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-4	nutriCA+stool-AA+blood+L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.481	0.858	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-4	nutriCA+stool+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.481	0.858	no	no	no	no	no	no	DM-DS
Bilophila	IL-4	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.528	0.858	no	no	no	no	no	no	DM-DS
Bilophila	IL-4	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.528	0.858	no	no	no	no	no	no	DM-DS
Bilophila	IL-4	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.528	0.858	no	no	no	no	no	no	DM-DS
Bilophila	IL-4	Bilophila+Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.528	0.858	no	no	no	no	no	no	DM-DS
Bilophila	IL-4	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.528	0.858	no	no	no	no	no	no	DM-DS
Bilophila	IL-4	Bilophila+Desulfovibrio+Antigen processing and presentation-Progesterone-mediated oocyte maturation+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.528	0.858	no	no	no	no	no	no	DM-DS
Bilophila	IL-4	Bilophila+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.528	0.858	no	no	no	no	no	no	DM-DS
Bilophila	IL-4	Bilophila+Desulfovibrio+Antigen processing and presentation+Leukocyte transendothelial migration-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.528	0.858	no	no	no	no	no	no	DM-DS
Bilophila	IL-4	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.528	0.858	no	no	no	no	no	no	DM-DS
Bilophila	IL-4	Bilophila+Desulfovibrio+Human cytomegalovirus infection-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.528	0.858	no	no	no	no	no	no	DM-DS
Bilophila	IL-4	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.528	0.858	no	no	no	no	no	no	DM-DS
Bilophila	IL-4	Bilophila+Desulfovibrio+Antigen processing and presentation-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.528	0.858	no	no	no	no	no	no	DM-DS
Bilophila	IL-4	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.528	0.858	no	no	no	no	no	no	DM-DS
GDCA+blood	IL-4	GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.632	0.858	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	IL-4	P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	urine_cometabolism	serum_cytokines	0.436	0.858	no	no	no	no	no	no	DM-DS
acetic acid C2+blood	IL-4	acetic acid C2+blood+d18:1-20:1-SM+blood-GUDCA+blood+UDCA+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.000193	0.858	up	dn	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	IL-4	isovaleric acid iso-C5+blood+n3+blood-FGF basic+IL-17A+IL-4	Indirect	serum_scfa	serum_cytokines	0.117	0.858	no	no	no	no	no	no	DM-DS
Clostridium	IL-4	Clostridium-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	IL-4	T-¦Á-MCA+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.48	0.858	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-4	12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-4	12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-4	12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-4	12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-4	12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-4	12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-4	12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-4	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	0.852	0.858	no	no	no	no	no	no	DM-DS
Blautia	IL-2	Blautia+Dorea-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia+Longevity regulating pathway - multiple species-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia+Longevity regulating pathway - multiple species+Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia+Peroxisome+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia+d18:1-18:0-SM+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia-Calcium signaling pathway-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia+Peroxisome+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia+Peroxisome+Apoptosis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia+Peroxisome+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia-Dopaminergic synapse-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia+Peroxisome-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia-Dopaminergic synapse+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia+Peroxisome+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia-Dopaminergic synapse-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia-Dopaminergic synapse-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia+Longevity regulating pathway - multiple species-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia-Dopaminergic synapse-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia+CDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia-Dopaminergic synapse-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia-Calcium signaling pathway-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia-Calcium signaling pathway-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Blautia	IL-2	Blautia+Dorea-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	DM-DS
Parabacteroides	IL-2	Parabacteroides-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	4.19E-05	0.522	no	up	up	no	no	no	DM-DS
Dorea	IL-2	Dorea-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	DM-DS
Dorea	IL-2	Dorea-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	DM-DS
Faecalibacterium	IL-2	Faecalibacterium-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0039	0.522	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	IL-2	Faecalibacterium+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0039	0.522	no	dn	dn	no	no	no	DM-DS
Bacteroides	IL-2	Bacteroides-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.000267	0.522	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-2	Bacteroides-cAMP signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.000267	0.522	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-2	Bacteroides+16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.000267	0.522	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-2	Bacteroides-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.000267	0.522	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-2	Bacteroides-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.000267	0.522	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-2	Bacteroides-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.000267	0.522	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-2	Bacteroides-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.000267	0.522	dn	dn	up	no	no	no	DM-DS
Propionic acid+stool	IL-2	Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.0436	0.522	dn	no	up	no	no	no	DM-DS
Propionic acid+stool	IL-2	Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.0436	0.522	dn	no	up	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Shigellosis-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-18:0/20:4-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-18:1/20:4-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-18:0/20:5-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Tight junction-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-ErbB signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-JAK-STAT signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-MicroRNAs in cancer+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-Pathways in cancer+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-ErbB signaling pathway-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-ErbB signaling pathway+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-JAK-STAT signaling pathway+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Huntington disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Non-alcoholic fatty liver disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-MicroRNAs in cancer+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-Pathways in cancer+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Alzheimer disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Parkinson disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-ErbB signaling pathway+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-JAK-STAT signaling pathway+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-JAK-STAT signaling pathway+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Huntington disease-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Non-alcoholic fatty liver disease-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Alzheimer disease-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Parkinson disease-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Tight junction-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-JAK-STAT signaling pathway+Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-Gastric cancer-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-Platinum drug resistance+Ribosome biogenesis in eukaryotes-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Tight junction-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-ErbB signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-JAK-STAT signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-FoxO signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-ErbB signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-JAK-STAT signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Tight junction-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-ErbB signaling pathway+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-JAK-STAT signaling pathway+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-MicroRNAs in cancer+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-Pathways in cancer+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Tight junction-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-ErbB signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-JAK-STAT signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Tight junction-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-FoxO signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-ErbB signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-JAK-STAT signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Huntington disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Non-alcoholic fatty liver disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-MicroRNAs in cancer+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-Pathways in cancer+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Alzheimer disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Parkinson disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-18:0/20:4-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+18:0/18:1-PE+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Tight junction-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-FoxO signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-ErbB signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-JAK-STAT signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Huntington disease-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+Alzheimer disease-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-Progesterone-mediated oocyte maturation+Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-Platinum drug resistance+Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-Progesterone-mediated oocyte maturation-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]-Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-2	[Ruminococcus]+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	DM-DS
GUDCA+blood	IL-2	GUDCA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.0766	0.522	no	no	dn	no	no	no	DM-DS
GUDCA+blood	IL-2	GUDCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.0766	0.522	no	no	dn	no	no	no	DM-DS
UDCA+blood	IL-2	UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.0939	0.522	no	no	dn	no	no	no	DM-DS
UDCA+blood	IL-2	UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.0939	0.522	no	no	dn	no	no	no	DM-DS
Acetic acid+stool	IL-2	Acetic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.0656	0.522	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	IL-2	Acetic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.0656	0.522	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	IL-2	Acetic acid+stool-16:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.0656	0.522	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	IL-2	Acetic acid+stool-18:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.0656	0.522	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	IL-2	Acetic acid+stool+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.0656	0.522	dn	no	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Vibrio cholerae infection-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+T cell receptor signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Platelet activation-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Ferroptosis+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+Platinum drug resistance+Ribosome biogenesis in eukaryotes-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Influenza A-Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+MAPK signaling pathway+Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+Platinum drug resistance+Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Rap1 signaling pathway-Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Ferroptosis-Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Ferroptosis+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Ferroptosis+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+T cell receptor signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-18:2/16:0-PC+blood+18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+18:0-LPC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+T cell receptor signaling pathway-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Vibrio cholerae infection-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+T cell receptor signaling pathway+Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Platelet activation-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Oxytocin signaling pathway-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Salivary secretion-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Alcoholism+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Ferroptosis+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Vibrio cholerae infection-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+T cell receptor signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+Signaling pathways regulating pluripotency of stem cells+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Platelet activation-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Oxytocin signaling pathway-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Salivary secretion-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+Colorectal cancer-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+Signaling pathways regulating pluripotency of stem cells-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+Gastric cancer-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+T cell receptor signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Platelet activation-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+MAPK signaling pathway-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Vibrio cholerae infection-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+T cell receptor signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+Signaling pathways regulating pluripotency of stem cells+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Platelet activation-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Oxytocin signaling pathway-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Rap1 signaling pathway-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Salivary secretion-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Vibrio cholerae infection-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+T cell receptor signaling pathway+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+Signaling pathways regulating pluripotency of stem cells+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Platelet activation-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Oxytocin signaling pathway-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Salivary secretion-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes+MAPK signaling pathway+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-DMG+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Platelet activation-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Oxytocin signaling pathway-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Rap1 signaling pathway-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Platelet activation-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Oxytocin signaling pathway-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Alistipes	IL-2	Alistipes-Rap1 signaling pathway-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	DM-DS
Butyricimonas	IL-2	Butyricimonas+Cholinergic synapse-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.17	0.522	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-2	Butyricimonas+20:5n3+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.17	0.522	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-2	Butyricimonas+Cholinergic synapse+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.17	0.522	no	no	no	no	no	no	DM-DS
Collinsella	IL-2	Collinsella-Renin secretion-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.128	0.522	no	no	no	no	no	no	DM-DS
Collinsella	IL-2	Collinsella-Inflammatory mediator regulation of TRP channels-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.128	0.522	no	no	no	no	no	no	DM-DS
Collinsella	IL-2	Collinsella-Renin secretion-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.128	0.522	no	no	no	no	no	no	DM-DS
Collinsella	IL-2	Collinsella-Inflammatory mediator regulation of TRP channels-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.128	0.522	no	no	no	no	no	no	DM-DS
Collinsella	IL-2	Collinsella-Inflammatory mediator regulation of TRP channels+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.128	0.522	no	no	no	no	no	no	DM-DS
Collinsella	IL-2	Collinsella-Renin secretion-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.128	0.522	no	no	no	no	no	no	DM-DS
Collinsella	IL-2	Collinsella-Inflammatory mediator regulation of TRP channels-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.128	0.522	no	no	no	no	no	no	DM-DS
Collinsella	IL-2	Collinsella-Renin secretion-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.128	0.522	no	no	no	no	no	no	DM-DS
Collinsella	IL-2	Collinsella-Inflammatory mediator regulation of TRP channels-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.128	0.522	no	no	no	no	no	no	DM-DS
Collinsella	IL-2	Collinsella-Renin secretion-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.128	0.522	no	no	no	no	no	no	DM-DS
Collinsella	IL-2	Collinsella-Inflammatory mediator regulation of TRP channels-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.128	0.522	no	no	no	no	no	no	DM-DS
Collinsella	IL-2	Collinsella-Renin secretion-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.128	0.522	no	no	no	no	no	no	DM-DS
Collinsella	IL-2	Collinsella-Inflammatory mediator regulation of TRP channels-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.128	0.522	no	no	no	no	no	no	DM-DS
Collinsella	IL-2	Collinsella-Renin secretion-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.128	0.522	no	no	no	no	no	no	DM-DS
Collinsella	IL-2	Collinsella-Inflammatory mediator regulation of TRP channels-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.128	0.522	no	no	no	no	no	no	DM-DS
Sarcina	IL-2	Sarcina+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0703	0.522	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-2	Methanosphaera-Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0703	0.522	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-2	Methanosphaera-Roseburia+16:0/16:1-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0703	0.522	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-2	Methanosphaera-Roseburia+16:0/16:1-PC+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0703	0.522	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-2	Methanosphaera-Roseburia+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0703	0.522	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-2	Methanosphaera-Roseburia+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0703	0.522	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-2	Methanosphaera-Roseburia+16:0/16:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0703	0.522	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-2	Methanosphaera-Roseburia+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0703	0.522	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-2	Methanosphaera-Roseburia-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0703	0.522	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-2	Methanosphaera-Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.0703	0.522	no	no	no	no	no	no	DM-DS
iso-DCA+stool	IL-2	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.155	0.522	no	no	no	no	no	no	DM-DS
iso-DCA+stool	IL-2	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.155	0.522	no	no	no	no	no	no	DM-DS
LCA+stool	IL-2	LCA+stool-UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.314	0.522	no	no	no	no	no	no	DM-DS
LCA+stool	IL-2	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.314	0.522	no	no	no	no	no	no	DM-DS
LCA+stool	IL-2	LCA+stool-UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.314	0.522	no	no	no	no	no	no	DM-DS
Akkermansia	IL-2	Akkermansia+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	DM-DS
Akkermansia	IL-2	Akkermansia+Proteoglycans in cancer-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	DM-DS
Akkermansia	IL-2	Akkermansia-Cholinergic synapse-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	DM-DS
Akkermansia	IL-2	Akkermansia-Cholinergic synapse+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	DM-DS
Akkermansia	IL-2	Akkermansia-Cytokine-cytokine receptor interaction+16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	DM-DS
Akkermansia	IL-2	Akkermansia+Proteoglycans in cancer-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	DM-DS
Akkermansia	IL-2	Akkermansia-Cytokine-cytokine receptor interaction-Cytosolic DNA-sensing pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	DM-DS
Akkermansia	IL-2	Akkermansia+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Glutamatergic synapse+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Gastric acid secretion-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Autophagy - animal+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+HIF-1 signaling pathway-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Proteasome-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-GABAergic synapse+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Proteoglycans in cancer-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Transcriptional misregulation in cancer+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Hepatitis B+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Glycolysis / Gluconeogenesis-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-MicroRNAs in cancer+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Focal adhesion-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Hippo signaling pathway-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Autophagy - animal+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+HIF-1 signaling pathway-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Proteasome-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Tight junction-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Glycolysis / Gluconeogenesis-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Focal adhesion-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Hippo signaling pathway-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Adherens junction-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Autophagy - animal+Apoptosis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+HIF-1 signaling pathway-Apoptosis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Proteasome-Apoptosis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Glycolysis / Gluconeogenesis-Apoptosis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Autophagy - animal+Cytosolic DNA-sensing pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Focal adhesion-Cytosolic DNA-sensing pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Autophagy - animal+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+HIF-1 signaling pathway-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Proteasome-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-FoxO signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Glycolysis / Gluconeogenesis-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Focal adhesion-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Hippo signaling pathway-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Adherens junction-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Autophagy - animal+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Proteasome-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Tight junction-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Glycolysis / Gluconeogenesis-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Focal adhesion-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Hippo signaling pathway-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Adherens junction-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-18:0/20:4-PI+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+DMG+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Glutamatergic synapse+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Autophagy - animal+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+HIF-1 signaling pathway-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Proteasome-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Glycolysis / Gluconeogenesis-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Focal adhesion-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Hippo signaling pathway-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Vibrio cholerae infection-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Gastric acid secretion-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Autophagy - animal+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Proteasome-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Transcriptional misregulation in cancer+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Tight junction-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Hepatitis B+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Bacterial invasion of epithelial cells-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Glycolysis / Gluconeogenesis-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-MicroRNAs in cancer+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Focal adhesion-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Hippo signaling pathway-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Adherens junction-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Vibrio cholerae infection-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Gastric acid secretion-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Autophagy - animal+Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Tight junction-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Focal adhesion-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Hippo signaling pathway-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Adherens junction-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Vibrio cholerae infection-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Gastric acid secretion-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Autophagy - animal+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Proteasome-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Transcriptional misregulation in cancer+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Tight junction-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Hepatitis B+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Bacterial invasion of epithelial cells-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Glycolysis / Gluconeogenesis-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-MicroRNAs in cancer+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Focal adhesion-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Hippo signaling pathway-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Adherens junction-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Vibrio cholerae infection-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Thyroid hormone signaling pathway-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Gastric acid secretion-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Autophagy - animal+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+HIF-1 signaling pathway-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Proteasome-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-GABAergic synapse+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-FoxO signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Proteoglycans in cancer-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Transcriptional misregulation in cancer+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Tight junction-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Hepatitis B+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Bacterial invasion of epithelial cells-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Glycolysis / Gluconeogenesis-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-MicroRNAs in cancer+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Focal adhesion-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Hippo signaling pathway-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Adherens junction-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Proteasome-cAMP signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Glycolysis / Gluconeogenesis-cAMP signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Autophagy - animal-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Proteasome+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-GABAergic synapse-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Focal adhesion+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Hippo signaling pathway+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Glutamatergic synapse+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Autophagy - animal+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+HIF-1 signaling pathway-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Proteasome-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-GABAergic synapse+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Glycolysis / Gluconeogenesis-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Hippo signaling pathway-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Leukocyte transendothelial migration-Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Glutamatergic synapse+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Vibrio cholerae infection-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Thyroid hormone signaling pathway-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Gastric acid secretion-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-Autophagy - animal+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+HIF-1 signaling pathway-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Proteasome-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-GABAergic synapse+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium-FoxO signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Tight junction-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Bacterial invasion of epithelial cells-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Glycolysis / Gluconeogenesis-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Focal adhesion-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Hippo signaling pathway-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Adherens junction-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Leukocyte transendothelial migration-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-2	Bifidobacterium+Leukocyte transendothelial migration-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	DM-DS
Ruminococcus	IL-2	Ruminococcus-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.335	0.522	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-2	Ruminococcus-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.335	0.522	no	no	no	no	no	no	DM-DS
GCDCA+blood	IL-2	GCDCA+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.31	0.522	no	no	no	no	no	no	DM-DS
ACA+blood	IL-2	ACA+blood+EPA+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.338	0.522	no	no	no	no	no	no	DM-DS
ACA+blood	IL-2	ACA+blood-decanoic acid C10+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.338	0.522	no	no	no	no	no	no	DM-DS
DCA+stool	IL-2	DCA+stool+HDCA+stool+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.195	0.522	no	no	no	no	no	no	DM-DS
DCA+stool	IL-2	DCA+stool+HDCA+stool+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.195	0.522	no	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-2	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.102	0.522	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-2	Butyric acid+stool+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.102	0.522	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-2	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.102	0.522	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-2	Butyric acid+stool+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.102	0.522	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-2	Butyric acid+stool-16:0/20:5-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.102	0.522	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-2	Butyric acid+stool+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.102	0.522	dn	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	IL-2	4-hydroxybenzoic acid+stool-DCA+stool+HDCA+stool+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.522	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	IL-2	4-hydroxybenzoic acid+stool-iso-LCA+stool-TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.522	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	IL-2	4-hydroxybenzoic acid+stool-iso-LCA+stool-TCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.522	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	IL-2	4-hydroxybenzoic acid+stool-DCA+stool+HDCA+stool+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.522	no	dn	no	no	no	no	DM-DS
Turicibacter	IL-2	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.269	0.522	no	no	no	no	no	no	DM-DS
Turicibacter	IL-2	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.269	0.522	no	no	no	no	no	no	DM-DS
Turicibacter	IL-2	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.269	0.522	no	no	no	no	no	no	DM-DS
Turicibacter	IL-2	Turicibacter+Desulfovibrio+Antigen processing and presentation+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.269	0.522	no	no	no	no	no	no	DM-DS
Turicibacter	IL-2	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.269	0.522	no	no	no	no	no	no	DM-DS
Turicibacter	IL-2	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.269	0.522	no	no	no	no	no	no	DM-DS
GCA+blood	IL-2	GCA+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.16	0.522	no	no	no	no	no	no	DM-DS
ACA+stool	IL-2	ACA+stool-L-Phenylalanine+stool-16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.417	0.522	no	no	no	no	no	no	DM-DS
ACA+stool	IL-2	ACA+stool-L-Phenylalanine+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.417	0.522	no	no	no	no	no	no	DM-DS
ACA+stool	IL-2	ACA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.417	0.522	no	no	no	no	no	no	DM-DS
ACA+stool	IL-2	ACA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.417	0.522	no	no	no	no	no	no	DM-DS
CDCA+blood	IL-2	CDCA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.506	0.522	no	no	no	no	no	no	DM-DS
CDCA+blood	IL-2	CDCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.506	0.522	no	no	no	no	no	no	DM-DS
capric acid C6+blood	IL-2	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	serum_scfa	serum_cytokines	0.433	0.522	no	no	no	no	no	no	DM-DS
capric acid C6+blood	IL-2	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	serum_scfa	serum_cytokines	0.433	0.522	no	no	no	no	no	no	DM-DS
Prevotella	IL-2	Prevotella+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	DM-DS
Prevotella	IL-2	Prevotella+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	DM-DS
iso-DCA+blood	IL-2	iso-DCA+blood+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.38	0.522	no	no	no	no	no	no	DM-DS
iso-DCA+blood	IL-2	iso-DCA+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.38	0.522	no	no	no	no	no	no	DM-DS
HCA+stool	IL-2	HCA+stool-HDCA+stool+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.155	0.522	no	no	no	no	no	no	DM-DS
HCA+stool	IL-2	HCA+stool-HDCA+stool+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.155	0.522	no	no	no	no	no	no	DM-DS
Roseburia	IL-2	Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.495	0.522	no	no	no	no	no	no	DM-DS
Roseburia	IL-2	Roseburia+16:0/16:1-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.495	0.522	no	no	no	no	no	no	DM-DS
Roseburia	IL-2	Roseburia+16:0/16:1-PC+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.495	0.522	no	no	no	no	no	no	DM-DS
Roseburia	IL-2	Roseburia+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.495	0.522	no	no	no	no	no	no	DM-DS
Roseburia	IL-2	Roseburia+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.495	0.522	no	no	no	no	no	no	DM-DS
Roseburia	IL-2	Roseburia+16:0/16:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.495	0.522	no	no	no	no	no	no	DM-DS
Roseburia	IL-2	Roseburia+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.495	0.522	no	no	no	no	no	no	DM-DS
Roseburia	IL-2	Roseburia-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.495	0.522	no	no	no	no	no	no	DM-DS
Roseburia	IL-2	Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.495	0.522	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	IL-2	12-ketoDCA+stool+HDCA+stool+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.505	0.522	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	IL-2	12-ketoDCA+stool+HDCA+stool+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.505	0.522	no	no	no	no	no	no	DM-DS
GLCA+blood	IL-2	GLCA+blood-SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.319	0.522	no	no	no	no	no	no	DM-DS
GLCA+blood	IL-2	GLCA+blood-SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.319	0.522	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-2	L-Tryptophan+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.557	0.522	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-2	L-Tryptophan+stool+8-HETE+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.557	0.522	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-2	L-Tryptophan+stool-18:3n6+blood-22:0/16:0-PE+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.557	0.522	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-2	L-Tryptophan+stool-18:3n6+blood-L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.557	0.522	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-2	L-Tryptophan+stool+8-HETE+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.557	0.522	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-2	L-Tryptophan+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.557	0.522	no	no	no	no	no	no	DM-DS
CA+blood	IL-2	CA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.606	0.522	no	no	no	no	no	no	DM-DS
CA+blood	IL-2	CA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.606	0.522	no	no	no	no	no	no	DM-DS
GUDCA+stool	IL-2	GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0085	0.522	no	dn	no	no	no	no	DM-DS
GUDCA+stool	IL-2	GUDCA+stool+12-HEPE+blood-DMG+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0085	0.522	no	dn	no	no	no	no	DM-DS
GUDCA+stool	IL-2	GUDCA+stool+12-HEPE+blood+16:0/20:5-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0085	0.522	no	dn	no	no	no	no	DM-DS
GUDCA+stool	IL-2	GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0085	0.522	no	dn	no	no	no	no	DM-DS
L-Phenylalanine+stool	IL-2	L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.398	0.522	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	IL-2	L-Phenylalanine+stool-16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.398	0.522	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	IL-2	L-Phenylalanine+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.398	0.522	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	IL-2	L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.398	0.522	no	no	no	no	no	no	DM-DS
GCA+stool	IL-2	GCA+stool+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0809	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus+Roseburia+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus+Roseburia+16:0/16:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus+Roseburia-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus+16:0/16:0-PC+blood+18:0/18:2-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus+16:0/16:0-PC+blood+18:1/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus+Roseburia+16:0/16:1-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus+16:0/16:0-PC+blood-18:0-LPC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus+Roseburia+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus+Roseburia+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus+16:0/16:0-PC+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus+16:0/16:0-PC+blood+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus+Roseburia+16:0/16:1-PC+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus+16:0/16:0-PC+blood+22:0/16:0-PE+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Coprococcus	IL-2	Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Rap1 signaling pathway-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Spliceosome+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Platelet activation-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Calcium signaling pathway-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Calcium signaling pathway-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+JAK-STAT signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Ribosome-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vascular smooth muscle contraction-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Oxidative phosphorylation-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Autophagy - animal+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+NF-kappa B signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Cardiac muscle contraction-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+FoxO signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Focal adhesion-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+JAK-STAT signaling pathway+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Autophagy - animal+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+NF-kappa B signaling pathway+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Focal adhesion-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+JAK-STAT signaling pathway+Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vibrio cholerae infection-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Dopaminergic synapse-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Morphine addiction-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Renin secretion-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vasopressin-regulated water reabsorption-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Melanogenesis-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Inflammatory mediator regulation of TRP channels-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Salivary secretion-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vascular smooth muscle contraction-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+T cell receptor signaling pathway+Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Platelet activation-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Gastric acid secretion-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Autophagy - animal+Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Circadian entrainment-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+NF-kappa B signaling pathway+Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Pancreatic secretion-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Focal adhesion-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Calcium signaling pathway-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Shigellosis-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+MAPK signaling pathway+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+JAK-STAT signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vascular smooth muscle contraction-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+T cell receptor signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Platelet activation-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Autophagy - animal+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Circadian entrainment-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+NF-kappa B signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Focal adhesion-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Thermogenesis+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Dopaminergic synapse+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Inflammatory mediator regulation of TRP channels+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vascular smooth muscle contraction+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+T cell receptor signaling pathway-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Autophagy - animal-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Circadian entrainment+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+NF-kappa B signaling pathway-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Focal adhesion+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Ribosome-Apoptosis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Oxidative phosphorylation-Apoptosis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Autophagy - animal+Apoptosis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+NF-kappa B signaling pathway+Apoptosis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+NF-kappa B signaling pathway+Sphingolipid signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Autophagy - animal+Cytosolic DNA-sensing pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+NF-kappa B signaling pathway+Cytosolic DNA-sensing pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Focal adhesion-Cytosolic DNA-sensing pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Thermogenesis-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+JAK-STAT signaling pathway+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Ribosome-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Prion disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Huntington disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Alzheimer disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Coronavirus disease - COVID-19-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Retrograde endocannabinoid signaling-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Renin secretion-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Hepatitis B+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Melanogenesis-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Inflammatory mediator regulation of TRP channels-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vascular smooth muscle contraction-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Oxidative phosphorylation-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Gastric acid secretion-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Autophagy - animal+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Non-alcoholic fatty liver disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Circadian entrainment-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+NF-kappa B signaling pathway+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Pathways of neurodegeneration - multiple diseases-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Cardiac muscle contraction-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Parkinson disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Focal adhesion-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Thermogenesis-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+JAK-STAT signaling pathway+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Ribosome-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Prion disease-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Huntington disease-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Alzheimer disease-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Retrograde endocannabinoid signaling-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Renin secretion-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Melanogenesis-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Inflammatory mediator regulation of TRP channels-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Oxidative phosphorylation-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Autophagy - animal+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Non-alcoholic fatty liver disease-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+NF-kappa B signaling pathway+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Pathways of neurodegeneration - multiple diseases-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Cardiac muscle contraction-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Parkinson disease-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Thermogenesis-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+JAK-STAT signaling pathway+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vibrio cholerae infection-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Prion disease-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Dopaminergic synapse-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Retrograde endocannabinoid signaling-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Renin secretion-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Hepatitis B+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vasopressin-regulated water reabsorption-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Melanogenesis-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Inflammatory mediator regulation of TRP channels-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Salivary secretion-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vascular smooth muscle contraction-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+T cell receptor signaling pathway+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Platelet activation-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Oxidative phosphorylation-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Gastric acid secretion-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Autophagy - animal+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Circadian entrainment-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+NF-kappa B signaling pathway+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Focal adhesion-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Thermogenesis-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+JAK-STAT signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vibrio cholerae infection-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Ribosome-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Prion disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Huntington disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Alzheimer disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Dopaminergic synapse-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Coronavirus disease - COVID-19-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Retrograde endocannabinoid signaling-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Renin secretion-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Hepatitis B+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Rap1 signaling pathway-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vasopressin-regulated water reabsorption-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Melanogenesis-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Inflammatory mediator regulation of TRP channels-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Salivary secretion-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vascular smooth muscle contraction-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+T cell receptor signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Platelet activation-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Oxidative phosphorylation-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Gastric acid secretion-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Autophagy - animal+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Non-alcoholic fatty liver disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Circadian entrainment-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+NF-kappa B signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Pathways of neurodegeneration - multiple diseases-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Cardiac muscle contraction-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+FoxO signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Parkinson disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Focal adhesion-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+JAK-STAT signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Ribosome-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vascular smooth muscle contraction-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+T cell receptor signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Oxidative phosphorylation-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Autophagy - animal+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+NF-kappa B signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Cardiac muscle contraction-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Focal adhesion-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+JAK-STAT signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vibrio cholerae infection-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Dopaminergic synapse-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Retrograde endocannabinoid signaling-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Renin secretion-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Hepatitis B+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Inflammatory mediator regulation of TRP channels-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Salivary secretion-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vascular smooth muscle contraction-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+T cell receptor signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Platelet activation-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Gastric acid secretion-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Autophagy - animal+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Circadian entrainment-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+NF-kappa B signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Focal adhesion-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Thermogenesis-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+JAK-STAT signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vibrio cholerae infection-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Ribosome-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Prion disease-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Huntington disease-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Alzheimer disease-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Dopaminergic synapse-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Retrograde endocannabinoid signaling-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Renin secretion-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Melanogenesis-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Inflammatory mediator regulation of TRP channels-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Vascular smooth muscle contraction-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+T cell receptor signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Platelet activation-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Oxidative phosphorylation-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Gastric acid secretion-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Autophagy - animal+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Circadian entrainment-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+NF-kappa B signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Cardiac muscle contraction-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+FoxO signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Focal adhesion-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Platinum drug resistance+Ribosome biogenesis in eukaryotes-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Platinum drug resistance+Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Progesterone-mediated oocyte maturation+Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Human cytomegalovirus infection-Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Rap1 signaling pathway-Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Spliceosome+Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+MAPK signaling pathway+Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Progesterone-mediated oocyte maturation-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Human cytomegalovirus infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+MAPK signaling pathway-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Rap1 signaling pathway-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira+Spliceosome+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
Oscillospira	IL-2	Oscillospira-Platelet activation-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	DM-DS
HCA+blood	IL-2	HCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.544	0.522	no	no	no	no	no	no	DM-DS
HCA+blood	IL-2	HCA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.544	0.522	no	no	no	no	no	no	DM-DS
iso-LCA+stool	IL-2	iso-LCA+stool-TCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.72	0.522	no	no	no	no	no	no	DM-DS
iso-LCA+stool	IL-2	iso-LCA+stool-TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.72	0.522	no	no	no	no	no	no	DM-DS
DCA+blood	IL-2	DCA+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.122	0.522	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-2	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-DMG+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.33	0.522	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-2	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood+16:0/20:5-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.33	0.522	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-2	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.33	0.522	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-2	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.33	0.522	no	no	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-2	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.522	up	up	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-2	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.522	up	up	no	no	no	no	DM-DS
nutriCA+blood	IL-2	nutriCA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.726	0.522	no	no	no	no	no	no	DM-DS
nutriCA+blood	IL-2	nutriCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.726	0.522	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IL-2	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.304	0.522	no	no	no	no	no	no	DM-DS
TCA+stool	IL-2	TCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.458	0.522	no	no	no	no	no	no	DM-DS
TCA+stool	IL-2	TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.458	0.522	no	no	no	no	no	no	DM-DS
HDCA+stool	IL-2	HDCA+stool+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.176	0.522	no	no	no	no	no	no	DM-DS
HDCA+stool	IL-2	HDCA+stool+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.176	0.522	no	no	no	no	no	no	DM-DS
Lachnospira	IL-2	Lachnospira-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.279	0.522	no	no	no	no	no	no	DM-DS
Lachnospira	IL-2	Lachnospira-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.279	0.522	no	no	no	no	no	no	DM-DS
Lachnospira	IL-2	Lachnospira-Cytosolic DNA-sensing pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.279	0.522	no	no	no	no	no	no	DM-DS
Lachnospira	IL-2	Lachnospira-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.279	0.522	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-2	Fusobacterium-18:0/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.628	0.522	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-2	Fusobacterium+16:0-LPC+blood-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.628	0.522	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-2	Fusobacterium-16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.628	0.522	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-2	Fusobacterium-18:0/18:2-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.628	0.522	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-2	Fusobacterium-18:0/18:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.628	0.522	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-2	Fusobacterium-18:1/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.628	0.522	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-2	Fusobacterium-18:0/18:0-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.628	0.522	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-2	Fusobacterium-18:0/18:1-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.628	0.522	no	no	no	no	no	no	DM-DS
GCDCA+stool	IL-2	GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-nutriCA+stool+18:1/20:3-PC+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-nutriCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:1-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:2-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-nutriCA+stool+18:1/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:0-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-HDCA+stool+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Neuroactive ligand-receptor interaction-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+16:0/20:4-PI+blood-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Proteasome-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Glycolysis / Gluconeogenesis-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Glutamatergic synapse+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	"Odoribacter-Growth hormone synthesis, secretion and action+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2"	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Ferroptosis+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Fc gamma R-mediated phagocytosis+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Proteasome-Apoptosis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Glycolysis / Gluconeogenesis-Apoptosis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Neuroactive ligand-receptor interaction+Apoptosis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Antigen processing and presentation+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Proteasome-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Glycolysis / Gluconeogenesis-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Neuroactive ligand-receptor interaction+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Proteasome-cAMP signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Glycolysis / Gluconeogenesis-cAMP signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Proteasome-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Glycolysis / Gluconeogenesis-Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Glutamatergic synapse+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	"Odoribacter-Growth hormone synthesis, secretion and action+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2"	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Long-term depression+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Ferroptosis+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Proteasome-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Glycolysis / Gluconeogenesis-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	"Odoribacter-Growth hormone synthesis, secretion and action+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2"	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Longevity regulating pathway - multiple species-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Proteasome+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Fc gamma R-mediated phagocytosis-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Morphine addiction-Hepatitis C+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Proteasome-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Glycolysis / Gluconeogenesis-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Neuroactive ligand-receptor interaction+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Pathogenic Escherichia coli infection-Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Necroptosis-Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Long-term depression-Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Ferroptosis-Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Longevity regulating pathway - multiple species+Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Endocrine resistance-Sphingolipid signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Proteasome-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Glycolysis / Gluconeogenesis-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Necroptosis-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Serotonergic synapse+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Proteasome-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Glycolysis / Gluconeogenesis-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Glutamatergic synapse+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	"Odoribacter-Growth hormone synthesis, secretion and action+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2"	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Neuroactive ligand-receptor interaction+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Leishmaniasis-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Gap junction+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Legionellosis-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Long-term depression+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Ferroptosis+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Fc gamma R-mediated phagocytosis+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Proteasome-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Glycolysis / Gluconeogenesis-Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Proteasome-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Glycolysis / Gluconeogenesis-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	"Odoribacter-Growth hormone synthesis, secretion and action+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2"	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Serotonergic synapse+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Proteasome-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Glycolysis / Gluconeogenesis-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Glutamatergic synapse+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Gap junction+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Necroptosis+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Long-term depression+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Carbon metabolism-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-Ferroptosis+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Longevity regulating pathway - multiple species-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter-HDCA+stool+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+Neuroactive ligand-receptor interaction-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Odoribacter	IL-2	Odoribacter+16:0/20:4-PI+blood-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus+Roseburia+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus+Roseburia+16:0/16:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus+Roseburia-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:0/18:2-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:1/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus+Roseburia+16:0/16:1-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus+16:0/16:0-PC+blood-18:0-LPC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus+Roseburia+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus+16:0/16:0-PC+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus+Roseburia+16:0/16:1-PC+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus+16:0/16:0-PC+blood+22:0/16:0-PE+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Actinomyces	IL-2	Actinomyces+Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.621	0.522	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IL-2	Isobutyric acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.408	0.522	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	IL-2	"2-hydroxyphenylacetic acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2"	Indirect	urine_cometabolism	serum_cytokines	0.763	0.522	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	IL-2	"2-hydroxyphenylacetic acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2"	Indirect	urine_cometabolism	serum_cytokines	0.763	0.522	no	no	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool-nutriCA+stool+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool-nutriCA+stool+18:1/20:3-PC+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool+L-Phenylalanine+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool-nutriCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool+L-Phenylalanine+stool-16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool-nutriCA+stool+18:0/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool-nutriCA+stool+18:0/18:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool-nutriCA+stool+18:0/18:0-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool-nutriCA+stool+18:1/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool-nutriCA+stool+18:0/20:2-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool-nutriCA+stool+18:0/18:1-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-2	Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	DM-DS
Caproic acid+stool	IL-2	Caproic acid+stool-TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.882	0.522	no	no	no	no	no	no	DM-DS
Caproic acid+stool	IL-2	Caproic acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.882	0.522	no	no	no	no	no	no	DM-DS
Caproic acid+stool	IL-2	Caproic acid+stool-TCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.882	0.522	no	no	no	no	no	no	DM-DS
Eggerthella	IL-2	Eggerthella-Yersinia infection+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.912	0.522	no	no	no	no	no	no	DM-DS
Eggerthella	IL-2	Eggerthella+Phosphatidylinositol signaling system-Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.912	0.522	no	no	no	no	no	no	DM-DS
Eggerthella	IL-2	Eggerthella-Yersinia infection-Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.912	0.522	no	no	no	no	no	no	DM-DS
Eggerthella	IL-2	Eggerthella+Phosphatidylinositol signaling system+Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.912	0.522	no	no	no	no	no	no	DM-DS
Eggerthella	IL-2	Eggerthella-Influenza A-Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.912	0.522	no	no	no	no	no	no	DM-DS
Eggerthella	IL-2	Eggerthella+AMPK signaling pathway-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.912	0.522	no	no	no	no	no	no	DM-DS
Eggerthella	IL-2	Eggerthella+Phosphatidylinositol signaling system-Cytosolic DNA-sensing pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.912	0.522	no	no	no	no	no	no	DM-DS
Eggerthella	IL-2	Eggerthella+Phosphatidylinositol signaling system+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.912	0.522	no	no	no	no	no	no	DM-DS
Eggerthella	IL-2	Eggerthella+Phosphatidylinositol signaling system-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.912	0.522	no	no	no	no	no	no	DM-DS
Eggerthella	IL-2	Eggerthella+Phosphatidylinositol signaling system-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.912	0.522	no	no	no	no	no	no	DM-DS
Eggerthella	IL-2	Eggerthella+AMPK signaling pathway-Apoptosis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.912	0.522	no	no	no	no	no	no	DM-DS
Eggerthella	IL-2	Eggerthella+Phosphatidylinositol signaling system-Apoptosis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.912	0.522	no	no	no	no	no	no	DM-DS
Eggerthella	IL-2	Eggerthella+AMPK signaling pathway-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.912	0.522	no	no	no	no	no	no	DM-DS
Eggerthella	IL-2	Eggerthella+Phosphatidylinositol signaling system-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.912	0.522	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-2	Anaerotruncus-Ruminococcus-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.904	0.522	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-2	Anaerotruncus-Ruminococcus-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.904	0.522	no	no	no	no	no	no	DM-DS
Anaerostipes	IL-2	Anaerostipes+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.568	0.522	no	no	no	no	no	no	DM-DS
Anaerostipes	IL-2	Anaerostipes+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.568	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-DHA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool+9-HODE+blood+AA+blood+DHA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-d18:1-14:0-SM+blood+d18:1-14:1-SM+blood-DHA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool+9-HODE+blood-d18:1-14:1-SM+blood-DHA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-L-2-Aminobutyric acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool+9-HODE+blood+AA+blood+L-2-Aminobutyric acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-L-2-Aminobutyric acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:3/16:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:3/18:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-20:3/18:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:5/18:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-d18:1-18:0-SM+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:2-PC+blood-d18:1-18:0-SM+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-EPA+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool+9-HODE+blood+AA+blood+EPA+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-22:6n3+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-d18:1-14:0-SM+blood+d18:1-20:0-SM+blood-decanoic acid C10+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood-Creatinine+blood+DMG+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood+DMG+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood-DMG+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood+16:0/20:5-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood-DL-methionine sulfoxide+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-d18:1-14:0-SM+blood-Ethanolamine+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-d18:1-14:0-SM+blood-L-Asparagine+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood+18:2-LPE+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-20:5n3+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood+18:1/18:0-PS+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood+18:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:1/20:4-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:2-PC+blood-20:1/20:4-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:1-PC+blood-20:1/20:4-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:5/18:0-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-22:0/16:0-PE+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-22:6-LPC+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:2-PC+blood+18:3-LPC+blood+18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:1-PC+blood+18:3-LPC+blood+18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood+18:3-LPC+blood+18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood-18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood+18:1/18:1-PG+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood-18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool+9-HODE+blood+AA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+24:0+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-d18:1-14:0-SM+blood-L-Asparagine+blood+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood-UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool+9-HODE+blood+AA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood+24:0+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-d18:1-14:0-SM+blood-L-Asparagine+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood-UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-2	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.241	0.522	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IL-2	Isovaleric acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_scfa	serum_cytokines	0.343	0.522	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-2	Paraprevotella-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.118	0.522	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-2	Paraprevotella+Ribosome biogenesis in eukaryotes-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.118	0.522	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	IL-2	¦Ø-MCA+stool+CDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.919	0.522	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-2	Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.785	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+Pathways in cancer+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+ErbB signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+ErbB signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+Pathways in cancer+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+ErbB signaling pathway+Prostate cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+Pathways in cancer+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+ErbB signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+ErbB signaling pathway+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+Pathways in cancer+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+ErbB signaling pathway+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+Signaling pathways regulating pluripotency of stem cells-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+Colorectal cancer-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+Gastric cancer-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+ErbB signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+ErbB signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+ErbB signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
Gemmiger	IL-2	Gemmiger+ErbB signaling pathway-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	DM-DS
GDCA+stool	IL-2	GDCA+stool-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.656	0.522	no	no	no	no	no	no	DM-DS
GDCA+stool	IL-2	GDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.656	0.522	no	no	no	no	no	no	DM-DS
Methanobrevibacter	IL-2	Methanobrevibacter-Alcoholism+Amoebiasis+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.629	0.522	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IL-2	L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.44	0.522	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IL-2	L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.44	0.522	no	no	no	no	no	no	DM-DS
CDCA+stool	IL-2	CDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.663	0.522	no	no	no	no	no	no	DM-DS
CA+stool	IL-2	CA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.827	0.522	no	no	no	no	no	no	DM-DS
CA+stool	IL-2	CA+stool+CDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.827	0.522	no	no	no	no	no	no	DM-DS
HDCA+blood	IL-2	HDCA+blood+Hypotaurine+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.483	0.522	no	no	no	no	no	no	DM-DS
HDCA+blood	IL-2	HDCA+blood+Hypotaurine+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.483	0.522	no	no	no	no	no	no	DM-DS
HDCA+blood	IL-2	HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.483	0.522	no	no	no	no	no	no	DM-DS
HDCA+blood	IL-2	HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.483	0.522	no	no	no	no	no	no	DM-DS
UDCA+stool	IL-2	UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.266	0.522	no	no	no	no	no	no	DM-DS
UDCA+stool	IL-2	UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.266	0.522	no	no	no	no	no	no	DM-DS
UDCA+stool	IL-2	UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.266	0.522	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-2	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.963	0.522	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-2	TDCA+stool-12-ketoDCA+blood-18:0/22:6-PI+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.963	0.522	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-2	TDCA+stool-12-ketoDCA+blood-18:0/22:6-PE+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.963	0.522	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-2	TDCA+stool-12-ketoDCA+blood-18:1/22:6-PE+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.963	0.522	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-2	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.963	0.522	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-2	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PE+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.963	0.522	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-2	TDCA+stool-12-ketoDCA+blood-16:1/18:1-PG+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.963	0.522	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-2	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.963	0.522	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-2	TDCA+stool-12-ketoDCA+blood-18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.963	0.522	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-2	TDCA+stool-12-ketoDCA+blood-18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.963	0.522	no	no	no	no	no	no	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	IL-2	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	urine_cometabolism	serum_cytokines	0.973	0.522	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-2	Desulfovibrio+Human T-cell leukemia virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.27	0.522	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-2	Desulfovibrio+Human cytomegalovirus infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.27	0.522	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-2	Desulfovibrio+Human immunodeficiency virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.27	0.522	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-2	Desulfovibrio+Antigen processing and presentation+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.27	0.522	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-2	Desulfovibrio+Herpes simplex virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.27	0.522	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-2	Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.27	0.522	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-2	nutriCA+stool+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.481	0.522	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-2	nutriCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.481	0.522	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-2	nutriCA+stool+18:0/18:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.481	0.522	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-2	nutriCA+stool+18:0/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.481	0.522	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-2	nutriCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.481	0.522	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-2	nutriCA+stool+18:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.481	0.522	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-2	nutriCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.481	0.522	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-2	nutriCA+stool+18:0/18:1-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.481	0.522	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-2	nutriCA+stool+18:0/18:0-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.481	0.522	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-2	nutriCA+stool+18:1/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.481	0.522	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-2	nutriCA+stool+18:0/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.481	0.522	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-2	nutriCA+stool+18:0/20:2-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.481	0.522	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-2	nutriCA+stool+18:1/20:3-PC+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.481	0.522	no	no	no	no	no	no	DM-DS
Bilophila	IL-2	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.528	0.522	no	no	no	no	no	no	DM-DS
Bilophila	IL-2	Bilophila+Desulfovibrio+Human cytomegalovirus infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.528	0.522	no	no	no	no	no	no	DM-DS
Bilophila	IL-2	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.528	0.522	no	no	no	no	no	no	DM-DS
Bilophila	IL-2	Bilophila+Desulfovibrio+Antigen processing and presentation+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.528	0.522	no	no	no	no	no	no	DM-DS
Bilophila	IL-2	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.528	0.522	no	no	no	no	no	no	DM-DS
Bilophila	IL-2	Bilophila+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.528	0.522	no	no	no	no	no	no	DM-DS
GDCA+blood	IL-2	GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.632	0.522	no	no	no	no	no	no	DM-DS
GDCA+blood	IL-2	GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.632	0.522	no	no	no	no	no	no	DM-DS
GDCA+blood	IL-2	GDCA+blood+Hypotaurine+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.632	0.522	no	no	no	no	no	no	DM-DS
GDCA+blood	IL-2	GDCA+blood+Hypotaurine+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.632	0.522	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	IL-2	P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	urine_cometabolism	serum_cytokines	0.436	0.522	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	IL-2	P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	urine_cometabolism	serum_cytokines	0.436	0.522	no	no	no	no	no	no	DM-DS
acetic acid C2+blood	IL-2	acetic acid C2+blood+d18:1-20:1-SM+blood-decanoic acid C10+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_scfa	serum_cytokines	0.000193	0.522	up	dn	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	IL-2	isovaleric acid iso-C5+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_scfa	serum_cytokines	0.117	0.522	no	no	no	no	no	no	DM-DS
Clostridium	IL-2	Clostridium-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.925	0.522	no	no	no	no	no	no	DM-DS
Clostridium	IL-2	Clostridium-Small cell lung cancer+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.925	0.522	no	no	no	no	no	no	DM-DS
Clostridium	IL-2	Clostridium-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.925	0.522	no	no	no	no	no	no	DM-DS
Clostridium	IL-2	Clostridium-cAMP signaling pathway+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.925	0.522	no	no	no	no	no	no	DM-DS
Clostridium	IL-2	Clostridium-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.925	0.522	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	IL-2	T-¦Á-MCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.48	0.522	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	IL-2	T-¦Á-MCA+stool-UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.48	0.522	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	IL-2	T-¦Á-MCA+stool-UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	stool_bileacids	serum_cytokines	0.48	0.522	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-2	12-ketoDCA+blood-18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.517	0.522	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-2	12-ketoDCA+blood-18:0/18:1-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.517	0.522	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-2	12-ketoDCA+blood-16:1/18:1-PG+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.517	0.522	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-2	12-ketoDCA+blood-18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.517	0.522	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-2	12-ketoDCA+blood-18:0/18:1-PE+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.517	0.522	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-2	12-ketoDCA+blood-18:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.517	0.522	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-2	12-ketoDCA+blood-18:1/22:6-PE+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.517	0.522	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-2	12-ketoDCA+blood-18:0/22:6-PI+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.517	0.522	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-2	12-ketoDCA+blood-16:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.517	0.522	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-2	12-ketoDCA+blood-18:0/22:6-PE+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	serum_bileacids	serum_cytokines	0.517	0.522	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-2	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13+IL-1b-IL-2"	Indirect	Genus	serum_cytokines	0.852	0.522	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-2	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A-IL-1b-IL-2"	Indirect	Genus	serum_cytokines	0.852	0.522	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-2	Butyricicoccus-18:2/20:4-PC+blood-DMG+blood-n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.852	0.522	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-2	Butyricicoccus-18:2/20:4-PC+blood+20:4n6+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.852	0.522	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-2	Butyricicoccus-18:2/20:4-PC+blood+EPA+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.852	0.522	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-2	"Butyricicoccus+12,13-EPOME+blood-18:0/20:4-PI+blood+n3+blood-FGF basic+IL-17A-IL-1b-IL-2"	Indirect	Genus	serum_cytokines	0.852	0.522	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-2	Butyricicoccus-18:2/20:4-PC+blood+20:4n6+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.852	0.522	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-2	Butyricicoccus-18:2/20:4-PC+blood+20:3/16:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2	Indirect	Genus	serum_cytokines	0.852	0.522	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-2	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2"	Indirect	Genus	serum_cytokines	0.852	0.522	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-2	"Butyricicoccus+12,13-EPOME+blood+18:0/18:1-PE+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2"	Indirect	Genus	serum_cytokines	0.852	0.522	no	no	no	no	no	no	DM-DS
Blautia	TNF-a	Blautia-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	DM-DS
Parabacteroides	TNF-a	Parabacteroides+Alistipes-IL-6-TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-DS
Parabacteroides	TNF-a	Parabacteroides+MAPK signaling pathway-IL-6-TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-DS
Parabacteroides	TNF-a	Parabacteroides-L-Tyrosine+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-DS
Parabacteroides	TNF-a	Parabacteroides+d18:1-22:0-SM+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-DS
Parabacteroides	TNF-a	Parabacteroides-TCA+stool-IL-9+TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-DS
Parabacteroides	TNF-a	Parabacteroides-18:1/18:1-PE+blood-IL-9+TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-DS
Dorea	TNF-a	Dorea+GCA+stool-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	DM-DS
Dorea	TNF-a	Dorea-Eotaxin+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	DM-DS
Dorea	TNF-a	Dorea+GCA+stool-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	DM-DS
Dorea	TNF-a	Dorea+Carbon metabolism-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	DM-DS
Dorea	TNF-a	Dorea-Eotaxin+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	DM-DS
Dorea	TNF-a	Dorea+Carbon metabolism+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	DM-DS
Dorea	TNF-a	Dorea-Eotaxin-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	DM-DS
Dorea	TNF-a	Dorea+L-Tyrosine+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	DM-DS
Dorea	TNF-a	Dorea+GDCA+stool+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	DM-DS
Dorea	TNF-a	Dorea+CDCA+stool+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	DM-DS
Faecalibacterium	TNF-a	Faecalibacterium-Phenylacetic acid+stool-L-Tyrosine+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.0039	0.613	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	TNF-a	Faecalibacterium+GCDCA+stool+L-Tyrosine+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.0039	0.613	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	TNF-a	Faecalibacterium-Phenylacetic acid+stool-16:0/16:1-PC+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.0039	0.613	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	TNF-a	Faecalibacterium+GCDCA+stool+16:0/16:1-PC+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.0039	0.613	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	TNF-a	Faecalibacterium-Phenylacetic acid+stool-16:0/20:3-PC+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.0039	0.613	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	TNF-a	Faecalibacterium+GCDCA+stool+16:0/20:3-PC+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.0039	0.613	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	TNF-a	Faecalibacterium+GCDCA+stool+GDCA+stool+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.0039	0.613	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	TNF-a	Faecalibacterium-d18:1-16:1-SM+blood+d18:1-22:0-SM+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.0039	0.613	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	TNF-a	Faecalibacterium-d18:1-14:0-SM+blood+d18:1-22:0-SM+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.0039	0.613	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	TNF-a	Faecalibacterium-Phenylacetic acid+stool-20:3n6+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.0039	0.613	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	TNF-a	Faecalibacterium+GCDCA+stool+20:3n6+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.0039	0.613	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	TNF-a	Faecalibacterium+GCDCA+stool+16:1/18:2-PG+blood-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.0039	0.613	no	dn	dn	no	no	no	DM-DS
TUDCA+blood	TNF-a	TUDCA+blood-TXB2+blood+Homovanillic acid+urine-MIP-1b+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.0282	0.613	no	no	dn	no	no	no	DM-DS
TUDCA+blood	TNF-a	TUDCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.0282	0.613	no	no	dn	no	no	no	DM-DS
Bacteroides	TNF-a	Bacteroides-Pathways in cancer+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	DM-DS
Bacteroides	TNF-a	Bacteroides-Chronic myeloid leukemia+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	DM-DS
Bacteroides	TNF-a	Bacteroides-Choline metabolism in cancer+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	DM-DS
Bacteroides	TNF-a	Bacteroides+Longevity regulating pathway - multiple species-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	DM-DS
Bacteroides	TNF-a	Bacteroides-Pathways in cancer-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	DM-DS
Bacteroides	TNF-a	Bacteroides+Leishmaniasis+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	DM-DS
Bacteroides	TNF-a	Bacteroides-16:1/18:2-PG+blood-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	DM-DS
Propionic acid+stool	TNF-a	Propionic acid+stool-L-Tyrosine+blood+IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0436	0.613	dn	no	up	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-Progesterone-mediated oocyte maturation+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-ErbB signaling pathway+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-Gastric cancer+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-Platinum drug resistance+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-Pathways in cancer+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-Non-small cell lung cancer+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]+Tight junction+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-FoxO signaling pathway-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-Progesterone-mediated oocyte maturation-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-ErbB signaling pathway-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-JAK-STAT signaling pathway-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-Gastric cancer-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-Platinum drug resistance-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-Pathways in cancer-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-Non-small cell lung cancer-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-Pancreatic cancer-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]+L-Tyrosine+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-Progesterone-mediated oocyte maturation+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]+18:1/18:1-PE+blood-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-ErbB signaling pathway+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-Gastric cancer+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-Platinum drug resistance+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	TNF-a	[Ruminococcus]-Non-small cell lung cancer+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-DS
GUDCA+blood	TNF-a	GUDCA+blood+UDCA+blood+Eotaxin+IL-9+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.0766	0.613	no	no	dn	no	no	no	DM-DS
GUDCA+blood	TNF-a	GUDCA+blood+UDCA+blood+Eotaxin+MIP-1b+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.0766	0.613	no	no	dn	no	no	no	DM-DS
GUDCA+blood	TNF-a	GUDCA+blood+UDCA+blood+Eotaxin-IL-6-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.0766	0.613	no	no	dn	no	no	no	DM-DS
UDCA+blood	TNF-a	UDCA+blood+Eotaxin-IL-6-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.0939	0.613	no	no	dn	no	no	no	DM-DS
UDCA+blood	TNF-a	UDCA+blood+Eotaxin+IL-9+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.0939	0.613	no	no	dn	no	no	no	DM-DS
UDCA+blood	TNF-a	UDCA+blood+Eotaxin+MIP-1b+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.0939	0.613	no	no	dn	no	no	no	DM-DS
Acetic acid+stool	TNF-a	Acetic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+MIP-1b+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0656	0.613	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	TNF-a	Acetic acid+stool-16:0/18:0-PS+blood-iso-LCA+blood+MIP-1b+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0656	0.613	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	TNF-a	Acetic acid+stool-18:0/18:0-PS+blood-iso-LCA+blood+MIP-1b+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0656	0.613	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	TNF-a	Acetic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+IL-9+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0656	0.613	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	TNF-a	Acetic acid+stool-14:0+blood+18:1/18:1-PE+blood-IL-9+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0656	0.613	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	TNF-a	Acetic acid+stool+18:1-LPC+blood-18:1/18:1-PE+blood-IL-9+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0656	0.613	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	TNF-a	Acetic acid+stool-18:0+blood+18:1/18:2-PG+blood-IL-9+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0656	0.613	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	TNF-a	Acetic acid+stool-16:0/18:0-PS+blood+20:4/18:0-PE+blood-IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0656	0.613	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	TNF-a	Acetic acid+stool-18:0/18:0-PS+blood+20:4/18:0-PE+blood-IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0656	0.613	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	TNF-a	Acetic acid+stool-16:0/18:0-PS+blood-GDCA+blood-IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0656	0.613	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	TNF-a	Acetic acid+stool-18:0/18:0-PS+blood-GDCA+blood-IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0656	0.613	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	TNF-a	Acetic acid+stool-18:0/18:0-PS+blood+18:0/18:1-PC+blood+IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0656	0.613	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	TNF-a	Acetic acid+stool-14:0+blood-d18:0-24:1-SM+blood+IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0656	0.613	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	TNF-a	Acetic acid+stool-14:0+blood-d18:1-22:0-SM+blood+IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0656	0.613	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	TNF-a	Acetic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-6-TNF-a	Indirect	stool_scfa	serum_cytokines	0.0656	0.613	dn	no	no	no	no	no	DM-DS
Alistipes	TNF-a	Alistipes-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.0114	0.613	no	up	no	no	no	no	DM-DS
Butyricimonas	TNF-a	Butyricimonas-iso-DCA+blood-IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	DM-DS
Collinsella	TNF-a	Collinsella+Roseburia+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-DS
5-Hydroxytryptamine+urine	TNF-a	5-Hydroxytryptamine+urine-Hippuric acid+urine-IL-6-TNF-a	Indirect	urine_cometabolism	serum_cytokines	0.171	0.613	no	no	no	no	no	no	DM-DS
Sarcina	TNF-a	Sarcina+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.0703	0.613	no	no	no	no	no	no	DM-DS
Methanosphaera	TNF-a	Methanosphaera-Roseburia+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.0703	0.613	no	no	no	no	no	no	DM-DS
iso-DCA+stool	TNF-a	iso-DCA+stool+Propionic acid+stool-L-Tyrosine+blood+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.155	0.613	no	no	no	no	no	no	DM-DS
LCA+stool	TNF-a	LCA+stool+MIP-1b+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.314	0.613	no	no	no	no	no	no	DM-DS
LCA+stool	TNF-a	LCA+stool+IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.314	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Breast cancer+Gastric cancer+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Leukocyte transendothelial migration-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Cholinergic synapse-TCA+stool-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Regulation of actin cytoskeleton-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia+P-hydroxyhippuric acid+urine+Eotaxin+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway+Chemical carcinogenesis - receptor activation+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-GCA+stool-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Cholinergic synapse+20:4/18:0-PE+blood-IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Cholinergic synapse-L-Tyrosine+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-CDCA+stool+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway+GDCA+blood-IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-GDCA+stool+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Breast cancer+Gastric cancer+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Leukocyte transendothelial migration-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Regulation of actin cytoskeleton-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia+P-hydroxyhippuric acid+urine+Eotaxin+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway+Chemical carcinogenesis - receptor activation+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Cytokine-cytokine receptor interaction+Longevity regulating pathway - multiple species-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Fluid shear stress and atherosclerosis-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Breast cancer-Fluid shear stress and atherosclerosis-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway+Cushing syndrome+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Cytokine-cytokine receptor interaction-Cushing syndrome+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Cytokine-cytokine receptor interaction+Neuroactive ligand-receptor interaction-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-GCA+stool-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia+Proteoglycans in cancer-Choline metabolism in cancer+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway+Choline metabolism in cancer+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Breast cancer+Choline metabolism in cancer+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Cytokine-cytokine receptor interaction-Spinocerebellar ataxia+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Cytokine-cytokine receptor interaction-Signaling pathways regulating pluripotency of stem cells+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Breast cancer+Gastric cancer-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Platelet activation+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Staphylococcus aureus infection+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Cytokine-cytokine receptor interaction+Staphylococcus aureus infection+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway+Hippuric acid+urine-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Breast cancer+Hippuric acid+urine-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Leishmaniasis+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Adherens junction+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Pathogenic Escherichia coli infection+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Cytokine-cytokine receptor interaction+Pathogenic Escherichia coli infection+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Leukocyte transendothelial migration+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Regulation of actin cytoskeleton+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia+P-hydroxyhippuric acid+urine+Eotaxin-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Asthma+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Breast cancer-Asthma+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Tight junction+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Systemic lupus erythematosus+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Cytokine-cytokine receptor interaction+Systemic lupus erythematosus+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Bacterial invasion of epithelial cells+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway+Chemical carcinogenesis - receptor activation-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Focal adhesion+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Longevity regulating pathway-Fluid shear stress and atherosclerosis+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Breast cancer-Fluid shear stress and atherosclerosis+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Cytokine-cytokine receptor interaction+IL-17 signaling pathway+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Cytokine-cytokine receptor interaction-Spinocerebellar ataxia-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Akkermansia	TNF-a	Akkermansia-Cytokine-cytokine receptor interaction-Signaling pathways regulating pluripotency of stem cells-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-DS
Bifidobacterium	TNF-a	Bifidobacterium+L-Tyrosine+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.105	0.613	no	dn	no	no	no	no	DM-DS
Bifidobacterium	TNF-a	Bifidobacterium+Leukocyte transendothelial migration-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.105	0.613	no	dn	no	no	no	no	DM-DS
Bifidobacterium	TNF-a	Bifidobacterium+Vibrio cholerae infection+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.105	0.613	no	dn	no	no	no	no	DM-DS
Bifidobacterium	TNF-a	Bifidobacterium-FoxO signaling pathway-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.105	0.613	no	dn	no	no	no	no	DM-DS
Bifidobacterium	TNF-a	Bifidobacterium+Tight junction+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.105	0.613	no	dn	no	no	no	no	DM-DS
Bifidobacterium	TNF-a	Bifidobacterium+Bacterial invasion of epithelial cells+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.105	0.613	no	dn	no	no	no	no	DM-DS
Bifidobacterium	TNF-a	Bifidobacterium+Focal adhesion+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.105	0.613	no	dn	no	no	no	no	DM-DS
Bifidobacterium	TNF-a	Bifidobacterium+Leukocyte transendothelial migration+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.105	0.613	no	dn	no	no	no	no	DM-DS
Bifidobacterium	TNF-a	Bifidobacterium+Adherens junction+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.105	0.613	no	dn	no	no	no	no	DM-DS
Bifidobacterium	TNF-a	Bifidobacterium+Leukocyte transendothelial migration-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.105	0.613	no	dn	no	no	no	no	DM-DS
3-Hydroxytyramine hydrochloride+urine	TNF-a	3-Hydroxytyramine hydrochloride+urine-Hippuric acid+urine-IL-6-TNF-a	Indirect	urine_cometabolism	serum_cytokines	0.288	0.613	no	no	no	no	no	no	DM-DS
Ruminococcus	TNF-a	Ruminococcus+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-DS
GCDCA+blood	TNF-a	GCDCA+blood+L-Tyrosine+blood+IP-10+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.31	0.613	no	no	no	no	no	no	DM-DS
ACA+blood	TNF-a	ACA+blood+EPA+blood+TXB2+blood+Homovanillic acid+urine-MIP-1b+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.338	0.613	no	no	no	no	no	no	DM-DS
ACA+blood	TNF-a	ACA+blood-decanoic acid C10+blood-TXB2+blood+Homovanillic acid+urine-MIP-1b+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.338	0.613	no	no	no	no	no	no	DM-DS
ACA+blood	TNF-a	ACA+blood+EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin+MIP-1b+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.338	0.613	no	no	no	no	no	no	DM-DS
ACA+blood	TNF-a	ACA+blood-decanoic acid C10+blood+L-Phenylalanine+blood+L-Tyrosine+blood+IP-10+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.338	0.613	no	no	no	no	no	no	DM-DS
ACA+blood	TNF-a	ACA+blood-decanoic acid C10+blood+L-Isoleucine+blood+L-Tyrosine+blood+IP-10+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.338	0.613	no	no	no	no	no	no	DM-DS
ACA+blood	TNF-a	ACA+blood+EPA+blood+TXB2+blood+Homovanillic acid+urine-IP-10+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.338	0.613	no	no	no	no	no	no	DM-DS
ACA+blood	TNF-a	ACA+blood-decanoic acid C10+blood-TXB2+blood+Homovanillic acid+urine-IP-10+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.338	0.613	no	no	no	no	no	no	DM-DS
ACA+blood	TNF-a	ACA+blood+EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin+IL-9+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.338	0.613	no	no	no	no	no	no	DM-DS
ACA+blood	TNF-a	ACA+blood+EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin-IL-6-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.338	0.613	no	no	no	no	no	no	DM-DS
DCA+stool	TNF-a	DCA+stool+MIP-1b+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-DS
Hippuric acid+urine	TNF-a	Hippuric acid+urine-IL-6-TNF-a	Indirect	urine_cometabolism	serum_cytokines	0.361	0.613	no	no	no	no	no	no	DM-DS
Butyric acid+stool	TNF-a	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+MIP-1b+TNF-a	Indirect	stool_scfa	serum_cytokines	0.102	0.613	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	TNF-a	Butyric acid+stool+L-Citrulline+blood+Eotaxin+MIP-1b+TNF-a	Indirect	stool_scfa	serum_cytokines	0.102	0.613	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	TNF-a	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+IL-9+TNF-a	Indirect	stool_scfa	serum_cytokines	0.102	0.613	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	TNF-a	Butyric acid+stool+L-Citrulline+blood+Eotaxin+IL-9+TNF-a	Indirect	stool_scfa	serum_cytokines	0.102	0.613	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	TNF-a	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-6-TNF-a	Indirect	stool_scfa	serum_cytokines	0.102	0.613	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	TNF-a	Butyric acid+stool+L-Citrulline+blood+Eotaxin-IL-6-TNF-a	Indirect	stool_scfa	serum_cytokines	0.102	0.613	dn	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	TNF-a	4-hydroxybenzoic acid+stool+TDCA+stool-MIP-1b+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.613	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	TNF-a	4-hydroxybenzoic acid+stool-LCA+stool+MIP-1b+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.613	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	TNF-a	4-hydroxybenzoic acid+stool-DCA+stool+MIP-1b+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.613	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	TNF-a	4-hydroxybenzoic acid+stool-iso-LCA+stool+MIP-1b+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.613	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	TNF-a	4-hydroxybenzoic acid+stool+TDCA+stool-IL-9+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.613	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	TNF-a	4-hydroxybenzoic acid+stool-LCA+stool+IL-9+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.613	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	TNF-a	4-hydroxybenzoic acid+stool-iso-LCA+stool+IL-9+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.613	no	dn	no	no	no	no	DM-DS
Turicibacter	TNF-a	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.269	0.613	no	no	no	no	no	no	DM-DS
Turicibacter	TNF-a	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.269	0.613	no	no	no	no	no	no	DM-DS
Turicibacter	TNF-a	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.269	0.613	no	no	no	no	no	no	DM-DS
Turicibacter	TNF-a	Turicibacter+Desulfovibrio+Antigen processing and presentation-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.269	0.613	no	no	no	no	no	no	DM-DS
Turicibacter	TNF-a	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.269	0.613	no	no	no	no	no	no	DM-DS
Turicibacter	TNF-a	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.269	0.613	no	no	no	no	no	no	DM-DS
Turicibacter	TNF-a	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.269	0.613	no	no	no	no	no	no	DM-DS
Turicibacter	TNF-a	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.269	0.613	no	no	no	no	no	no	DM-DS
Turicibacter	TNF-a	Turicibacter+Desulfovibrio+Antigen processing and presentation-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.269	0.613	no	no	no	no	no	no	DM-DS
Turicibacter	TNF-a	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.269	0.613	no	no	no	no	no	no	DM-DS
Turicibacter	TNF-a	Turicibacter+Desulfovibrio+Antigen processing and presentation+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.269	0.613	no	no	no	no	no	no	DM-DS
GCA+blood	TNF-a	GCA+blood+TDCA+blood-IP-10+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.16	0.613	no	no	no	no	no	no	DM-DS
ACA+stool	TNF-a	ACA+stool-L-Tryptophan+stool+Homovanillic acid+urine-MIP-1b+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.417	0.613	no	no	no	no	no	no	DM-DS
ACA+stool	TNF-a	ACA+stool-L-Phenylalanine+stool+Homovanillic acid+urine-MIP-1b+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.417	0.613	no	no	no	no	no	no	DM-DS
ACA+stool	TNF-a	ACA+stool-L-Phenylalanine+stool-16:0/20:3-PC+blood+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.417	0.613	no	no	no	no	no	no	DM-DS
ACA+stool	TNF-a	ACA+stool-L-Tryptophan+stool+Homovanillic acid+urine-IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.417	0.613	no	no	no	no	no	no	DM-DS
ACA+stool	TNF-a	ACA+stool-L-Phenylalanine+stool+Homovanillic acid+urine-IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.417	0.613	no	no	no	no	no	no	DM-DS
ACA+stool	TNF-a	ACA+stool-Kynurenic acid+stool-nutriCA+stool-IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.417	0.613	no	no	no	no	no	no	DM-DS
CDCA+blood	TNF-a	CDCA+blood+UDCA+blood+Eotaxin+IL-9+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.506	0.613	no	no	no	no	no	no	DM-DS
CDCA+blood	TNF-a	CDCA+blood+GCDCA+blood+L-Tyrosine+blood+IP-10+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.506	0.613	no	no	no	no	no	no	DM-DS
CDCA+blood	TNF-a	CDCA+blood+UDCA+blood+Eotaxin+MIP-1b+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.506	0.613	no	no	no	no	no	no	DM-DS
CDCA+blood	TNF-a	CDCA+blood+UDCA+blood+Eotaxin-IL-6-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.506	0.613	no	no	no	no	no	no	DM-DS
capric acid C6+blood	TNF-a	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin-IL-6-TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	DM-DS
capric acid C6+blood	TNF-a	capric acid C6+blood-HCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	DM-DS
capric acid C6+blood	TNF-a	capric acid C6+blood-HCA+blood-TXB2+blood+Homovanillic acid+urine-MIP-1b+TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	DM-DS
capric acid C6+blood	TNF-a	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin+MIP-1b+TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	DM-DS
capric acid C6+blood	TNF-a	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin+IL-9+TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	DM-DS
Prevotella	TNF-a	Prevotella+TDCA+blood-IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.287	0.613	no	no	no	no	no	no	DM-DS
Prevotella	TNF-a	Prevotella+GDCA+blood-IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.287	0.613	no	no	no	no	no	no	DM-DS
Prevotella	TNF-a	Prevotella+20:4/18:0-PE+blood-IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.287	0.613	no	no	no	no	no	no	DM-DS
Prevotella	TNF-a	Prevotella-Tight junction+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.287	0.613	no	no	no	no	no	no	DM-DS
Prevotella	TNF-a	Prevotella-Bacterial invasion of epithelial cells+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.287	0.613	no	no	no	no	no	no	DM-DS
Prevotella	TNF-a	Prevotella+FoxO signaling pathway-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.287	0.613	no	no	no	no	no	no	DM-DS
Prevotella	TNF-a	Prevotella+Hippuric acid+urine-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.287	0.613	no	no	no	no	no	no	DM-DS
Prevotella	TNF-a	Prevotella-Focal adhesion+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.287	0.613	no	no	no	no	no	no	DM-DS
Prevotella	TNF-a	Prevotella+Choline metabolism in cancer+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.287	0.613	no	no	no	no	no	no	DM-DS
TCA+blood	TNF-a	TCA+blood+TUDCA+blood-TXB2+blood+Homovanillic acid+urine-MIP-1b+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.339	0.613	no	no	no	no	no	no	DM-DS
TCA+blood	TNF-a	TCA+blood+TUDCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.339	0.613	no	no	no	no	no	no	DM-DS
iso-DCA+blood	TNF-a	iso-DCA+blood-IP-10+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.38	0.613	no	no	no	no	no	no	DM-DS
HCA+stool	TNF-a	HCA+stool-HDCA+stool+IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.155	0.613	no	no	no	no	no	no	DM-DS
Roseburia	TNF-a	Roseburia+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.495	0.613	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	TNF-a	12-ketoDCA+stool-TDCA+stool-MIP-1b+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.505	0.613	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	TNF-a	12-ketoDCA+stool+LCA+stool+MIP-1b+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.505	0.613	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	TNF-a	12-ketoDCA+stool+iso-LCA+stool+MIP-1b+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.505	0.613	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	TNF-a	12-ketoDCA+stool+DCA+stool+MIP-1b+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.505	0.613	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	TNF-a	12-ketoDCA+stool-GCA+stool-MIP-1b+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.505	0.613	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	TNF-a	12-ketoDCA+stool+Hippuric acid+urine-IL-6-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.505	0.613	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	TNF-a	12-ketoDCA+stool-TDCA+stool-IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.505	0.613	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	TNF-a	12-ketoDCA+stool+LCA+stool+IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.505	0.613	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	TNF-a	12-ketoDCA+stool+iso-LCA+stool+IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.505	0.613	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	TNF-a	12-ketoDCA+stool+HDCA+stool+IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.505	0.613	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	TNF-a	12-ketoDCA+stool-GCA+stool-IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.505	0.613	no	no	no	no	no	no	DM-DS
GLCA+blood	TNF-a	GLCA+blood+MIP-1b+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.319	0.613	no	no	no	no	no	no	DM-DS
GLCA+blood	TNF-a	GLCA+blood+IL-9+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.319	0.613	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	TNF-a	L-Tryptophan+stool+Homovanillic acid+urine-MIP-1b+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.557	0.613	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	TNF-a	L-Tryptophan+stool+Homovanillic acid+urine-IP-10+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.557	0.613	no	no	no	no	no	no	DM-DS
CA+blood	TNF-a	CA+blood+TDCA+blood-IP-10+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.606	0.613	no	no	no	no	no	no	DM-DS
GUDCA+stool	TNF-a	GUDCA+stool+12-HEPE+blood-L-Tyrosine+blood+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0085	0.613	no	dn	no	no	no	no	DM-DS
L-Phenylalanine+stool	TNF-a	L-Phenylalanine+stool-16:0/20:3-PC+blood+IP-10+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.398	0.613	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	TNF-a	L-Phenylalanine+stool+Homovanillic acid+urine-IP-10+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.398	0.613	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	TNF-a	L-Phenylalanine+stool+Homovanillic acid+urine-MIP-1b+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.398	0.613	no	no	no	no	no	no	DM-DS
butyric acid C4+blood	TNF-a	butyric acid C4+blood+iso-LCA+blood+MIP-1b+TNF-a	Indirect	serum_scfa	serum_cytokines	0.407	0.613	no	no	no	no	no	no	DM-DS
GCA+stool	TNF-a	GCA+stool-MIP-1b+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0809	0.613	no	no	no	no	no	no	DM-DS
GCA+stool	TNF-a	GCA+stool-IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0809	0.613	no	no	no	no	no	no	DM-DS
Coprococcus	TNF-a	Coprococcus+L-Tyrosine+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.612	0.613	no	no	no	no	no	no	DM-DS
Coprococcus	TNF-a	Coprococcus+Roseburia+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.612	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira+JAK-STAT signaling pathway-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira-Vibrio cholerae infection+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira+Platinum drug resistance-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira+Progesterone-mediated oocyte maturation-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira-Rap1 signaling pathway+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira+Spliceosome-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira+T cell receptor signaling pathway-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira+MAPK signaling pathway-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira-Platelet activation+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira+FoxO signaling pathway-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira-Focal adhesion+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira+Platinum drug resistance+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira+Progesterone-mediated oocyte maturation+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira-Human cytomegalovirus infection-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira+Spliceosome+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira+T cell receptor signaling pathway+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira+Platinum drug resistance+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira+Progesterone-mediated oocyte maturation+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira-Human cytomegalovirus infection-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira+Spliceosome+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
Oscillospira	TNF-a	Oscillospira+T cell receptor signaling pathway+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-DS
HCA+blood	TNF-a	HCA+blood+UDCA+blood+Eotaxin+IL-9+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.544	0.613	no	no	no	no	no	no	DM-DS
HCA+blood	TNF-a	HCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.544	0.613	no	no	no	no	no	no	DM-DS
HCA+blood	TNF-a	HCA+blood-TXB2+blood+Homovanillic acid+urine-MIP-1b+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.544	0.613	no	no	no	no	no	no	DM-DS
HCA+blood	TNF-a	HCA+blood+UDCA+blood+Eotaxin+MIP-1b+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.544	0.613	no	no	no	no	no	no	DM-DS
HCA+blood	TNF-a	HCA+blood+UDCA+blood+Eotaxin-IL-6-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.544	0.613	no	no	no	no	no	no	DM-DS
iso-LCA+stool	TNF-a	iso-LCA+stool+IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.72	0.613	no	no	no	no	no	no	DM-DS
iso-LCA+stool	TNF-a	iso-LCA+stool+MIP-1b+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.72	0.613	no	no	no	no	no	no	DM-DS
DCA+blood	TNF-a	DCA+blood+nutriCA+blood+UDCA+blood+Eotaxin-IL-6-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.122	0.613	no	no	no	no	no	no	DM-DS
DCA+blood	TNF-a	DCA+blood+L-Histidine+blood+L-Lysine+blood+L-Tyrosine+blood+IP-10+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.122	0.613	no	no	no	no	no	no	DM-DS
DCA+blood	TNF-a	DCA+blood+L-Histidine+blood+L-Isoleucine+blood+L-Tyrosine+blood+IP-10+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.122	0.613	no	no	no	no	no	no	DM-DS
DCA+blood	TNF-a	DCA+blood+L-Histidine+blood+L-Methionine+blood+L-Tyrosine+blood+IP-10+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.122	0.613	no	no	no	no	no	no	DM-DS
DCA+blood	TNF-a	DCA+blood+nutriCA+blood+UDCA+blood+Eotaxin+MIP-1b+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.122	0.613	no	no	no	no	no	no	DM-DS
DCA+blood	TNF-a	DCA+blood+nutriCA+blood+UDCA+blood+Eotaxin+IL-9+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.122	0.613	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	TNF-a	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool+9-HODE+blood+AA+blood-IP-10+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.33	0.613	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	TNF-a	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Tyrosine+blood+IP-10+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.33	0.613	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	TNF-a	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-d18:1-14:0-SM+blood+d18:1-22:0-SM+blood+IP-10+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.33	0.613	no	no	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	TNF-a	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-9+TNF-a"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.613	up	up	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	TNF-a	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+MIP-1b+TNF-a"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.613	up	up	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	TNF-a	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-6-TNF-a"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.613	up	up	no	no	no	no	DM-DS
nutriCA+blood	TNF-a	nutriCA+blood+UDCA+blood+Eotaxin-IL-6-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.726	0.613	no	no	no	no	no	no	DM-DS
nutriCA+blood	TNF-a	nutriCA+blood+UDCA+blood+Eotaxin+MIP-1b+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.726	0.613	no	no	no	no	no	no	DM-DS
nutriCA+blood	TNF-a	nutriCA+blood+UDCA+blood+Eotaxin+IL-9+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.726	0.613	no	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+urine	TNF-a	4-hydroxybenzoic acid+urine+Homovanillic acid+urine-MIP-1b+TNF-a	Indirect	urine_cometabolism	serum_cytokines	0.52	0.613	no	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+urine	TNF-a	4-hydroxybenzoic acid+urine+Homovanillic acid+urine-IP-10+TNF-a	Indirect	urine_cometabolism	serum_cytokines	0.52	0.613	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	TNF-a	Indole-3-Acetic acid+stool-nutriCA+stool-IL-9+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.613	no	no	no	no	no	no	DM-DS
TCA+stool	TNF-a	TCA+stool-IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.458	0.613	no	no	no	no	no	no	DM-DS
HDCA+stool	TNF-a	HDCA+stool+IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.176	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Vibrio cholerae infection+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Carbon metabolism+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Adherens junction+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-p53 signaling pathway-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Platelet activation+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Bacterial invasion of epithelial cells+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-Progesterone-mediated oocyte maturation-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-Platinum drug resistance-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-T cell receptor signaling pathway-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Regulation of actin cytoskeleton+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Rap1 signaling pathway+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-Spliceosome-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-Hippuric acid+urine-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-Signaling pathways regulating pluripotency of stem cells-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Tight junction+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Leukocyte transendothelial migration+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-FoxO signaling pathway-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-ErbB signaling pathway-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Oxytocin signaling pathway+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-JAK-STAT signaling pathway-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-Non-small cell lung cancer-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Focal adhesion+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Fluid shear stress and atherosclerosis+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Carbon metabolism-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-p53 signaling pathway+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-Chronic myeloid leukemia+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-Progesterone-mediated oocyte maturation+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-Platinum drug resistance+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-T cell receptor signaling pathway+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Regulation of actin cytoskeleton-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-Spliceosome+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-Signaling pathways regulating pluripotency of stem cells+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Leukocyte transendothelial migration-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-ErbB signaling pathway+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-Non-small cell lung cancer+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Fluid shear stress and atherosclerosis-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+TCA+stool-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-p53 signaling pathway+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-Progesterone-mediated oocyte maturation+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-Platinum drug resistance+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-T cell receptor signaling pathway+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Regulation of actin cytoskeleton-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-Spliceosome+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira+Leukocyte transendothelial migration-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-ErbB signaling pathway+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Lachnospira	TNF-a	Lachnospira-Non-small cell lung cancer+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-DS
Fusobacterium	TNF-a	Fusobacterium-18:0/18:0-PC+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.628	0.613	no	no	no	no	no	no	DM-DS
Fusobacterium	TNF-a	Fusobacterium-16:0/20:3-PC+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.628	0.613	no	no	no	no	no	no	DM-DS
Fusobacterium	TNF-a	Fusobacterium-18:0/18:1-PC+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.628	0.613	no	no	no	no	no	no	DM-DS
GCDCA+stool	TNF-a	GCDCA+stool+L-Tyrosine+blood+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-DS
GCDCA+stool	TNF-a	GCDCA+stool+20:3n6+blood+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-DS
GCDCA+stool	TNF-a	GCDCA+stool+16:0/16:1-PC+blood+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-DS
GCDCA+stool	TNF-a	GCDCA+stool+16:0/20:3-PC+blood+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-DS
GCDCA+stool	TNF-a	GCDCA+stool+GDCA+stool+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-DS
GCDCA+stool	TNF-a	GCDCA+stool+16:1/18:2-PG+blood-IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	TNF-a	5-Hydroxytryptamine+stool-nutriCA+stool-IL-9+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.613	dn	dn	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter-DCA+stool+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter-iso-LCA+stool+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter+GCA+stool-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter+Antigen processing and presentation-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter-Cushing syndrome+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter+Neuroactive ligand-receptor interaction-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter-Chemical carcinogenesis - receptor activation+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter-LCA+stool+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter+Carbon metabolism-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter+Longevity regulating pathway - multiple species-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter+Pathogenic Escherichia coli infection+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter+Antigen processing and presentation+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter+Leishmaniasis+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter-Chemical carcinogenesis - receptor activation-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter+Carbon metabolism+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter-iso-LCA+stool+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter+GCA+stool-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter+Antigen processing and presentation-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter-HDCA+stool+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter-Chemical carcinogenesis - receptor activation+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Odoribacter	TNF-a	Odoribacter-LCA+stool+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-DS
Actinomyces	TNF-a	Actinomyces+Coprococcus+L-Tyrosine+blood+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.621	0.613	no	no	no	no	no	no	DM-DS
Actinomyces	TNF-a	Actinomyces+Coprococcus+Roseburia+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.621	0.613	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	TNF-a	Isobutyric acid+stool-nutriCA+stool-IL-9+TNF-a	Indirect	stool_scfa	serum_cytokines	0.408	0.613	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	TNF-a	2-hydroxyphenylacetic acid+urine+Homovanillic acid+urine-MIP-1b+TNF-a	Indirect	urine_cometabolism	serum_cytokines	0.763	0.613	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	TNF-a	2-hydroxyphenylacetic acid+urine+Homovanillic acid+urine-IP-10+TNF-a	Indirect	urine_cometabolism	serum_cytokines	0.763	0.613	no	no	no	no	no	no	DM-DS
Kynurenic acid+stool	TNF-a	Kynurenic acid+stool-nutriCA+stool-IL-9+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.613	dn	dn	no	no	no	no	DM-DS
Caproic acid+stool	TNF-a	Caproic acid+stool-TCA+stool-IL-9+TNF-a	Indirect	stool_scfa	serum_cytokines	0.882	0.613	no	no	no	no	no	no	DM-DS
Caproic acid+stool	TNF-a	Caproic acid+stool-GCA+stool-IL-9+TNF-a	Indirect	stool_scfa	serum_cytokines	0.882	0.613	no	no	no	no	no	no	DM-DS
Caproic acid+stool	TNF-a	Caproic acid+stool-TDCA+stool-IL-9+TNF-a	Indirect	stool_scfa	serum_cytokines	0.882	0.613	no	no	no	no	no	no	DM-DS
Caproic acid+stool	TNF-a	Caproic acid+stool-GCA+stool-MIP-1b+TNF-a	Indirect	stool_scfa	serum_cytokines	0.882	0.613	no	no	no	no	no	no	DM-DS
Caproic acid+stool	TNF-a	Caproic acid+stool-TDCA+stool-MIP-1b+TNF-a	Indirect	stool_scfa	serum_cytokines	0.882	0.613	no	no	no	no	no	no	DM-DS
Eggerthella	TNF-a	Eggerthella+Phosphatidylinositol signaling system-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.912	0.613	no	no	no	no	no	no	DM-DS
Eggerthella	TNF-a	Eggerthella-iso-LCA+stool+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.912	0.613	no	no	no	no	no	no	DM-DS
Eggerthella	TNF-a	Eggerthella+nutriCA+stool-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.912	0.613	no	no	no	no	no	no	DM-DS
Eggerthella	TNF-a	Eggerthella-iso-LCA+stool+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.912	0.613	no	no	no	no	no	no	DM-DS
Anaerotruncus	TNF-a	Anaerotruncus-Ruminococcus+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.904	0.613	no	no	no	no	no	no	DM-DS
Anaerostipes	TNF-a	Anaerostipes-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	DM-DS
TUDCA+stool	TNF-a	TUDCA+stool+9-HODE+blood+AA+blood-IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.241	0.613	no	no	no	no	no	no	DM-DS
TUDCA+stool	TNF-a	TUDCA+stool-d18:1-14:0-SM+blood+d18:1-22:0-SM+blood+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.241	0.613	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool-UDCA+stool+18:0/20:3-PI+blood-IL-9+TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool-UDCA+stool-GDCA+blood-IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool-UDCA+stool-TDCA+blood-IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool+Phenylacetic acid+stool-20:3n6+blood+IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool+Phenylacetic acid+stool-L-Tyrosine+blood+IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool-UDCA+stool+L-Tyrosine+blood+IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool+L-Phenylalanine+stool+Homovanillic acid+urine-IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/16:1-PC+blood+IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool+L-Phenylalanine+stool-16:0/20:3-PC+blood+IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/20:3-PC+blood+IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool-UDCA+stool+16:0/20:3-PC+blood+IP-10+TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool-UDCA+stool-iso-LCA+blood+MIP-1b+TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool+L-Phenylalanine+stool+Homovanillic acid+urine-MIP-1b+TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	DM-DS
Paraprevotella	TNF-a	Paraprevotella+IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.118	0.613	no	no	no	no	no	no	DM-DS
Homovanillic acid+urine	TNF-a	Homovanillic acid+urine-MIP-1b+TNF-a	Indirect	urine_cometabolism	serum_cytokines	0.45	0.613	no	no	no	no	no	no	DM-DS
Homovanillic acid+urine	TNF-a	Homovanillic acid+urine-IP-10+TNF-a	Indirect	urine_cometabolism	serum_cytokines	0.45	0.613	no	no	no	no	no	no	DM-DS
TDCA+blood	TNF-a	TDCA+blood-IP-10+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.155	0.613	no	up	no	no	no	no	DM-DS
iso-LCA+blood	TNF-a	iso-LCA+blood+MIP-1b+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.507	0.613	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	TNF-a	¦Ø-MCA+stool+GDCA+stool+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.919	0.613	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	TNF-a	¦Ø-MCA+stool+CDCA+stool+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.919	0.613	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	TNF-a	Phenylacetic acid+stool-16:0/20:3-PC+blood+IP-10+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.785	0.613	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	TNF-a	Phenylacetic acid+stool-16:0/16:1-PC+blood+IP-10+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.785	0.613	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	TNF-a	Phenylacetic acid+stool-L-Tyrosine+blood+IP-10+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.785	0.613	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	TNF-a	Phenylacetic acid+stool-20:3n6+blood+IP-10+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.785	0.613	no	no	no	no	no	no	DM-DS
Gemmiger	TNF-a	Gemmiger+ErbB signaling pathway+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.595	0.613	no	no	no	no	no	no	DM-DS
Gemmiger	TNF-a	Gemmiger+Gastric cancer+IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.595	0.613	no	no	no	no	no	no	DM-DS
Gemmiger	TNF-a	Gemmiger+Signaling pathways regulating pluripotency of stem cells-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.595	0.613	no	no	no	no	no	no	DM-DS
Gemmiger	TNF-a	Gemmiger+Pathways in cancer-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.595	0.613	no	no	no	no	no	no	DM-DS
Gemmiger	TNF-a	Gemmiger+ErbB signaling pathway-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.595	0.613	no	no	no	no	no	no	DM-DS
Gemmiger	TNF-a	Gemmiger+Gastric cancer-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.595	0.613	no	no	no	no	no	no	DM-DS
Gemmiger	TNF-a	Gemmiger+Signaling pathways regulating pluripotency of stem cells+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.595	0.613	no	no	no	no	no	no	DM-DS
Gemmiger	TNF-a	Gemmiger+Pathways in cancer+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.595	0.613	no	no	no	no	no	no	DM-DS
Gemmiger	TNF-a	Gemmiger+ErbB signaling pathway+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.595	0.613	no	no	no	no	no	no	DM-DS
Gemmiger	TNF-a	Gemmiger+Colorectal cancer+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.595	0.613	no	no	no	no	no	no	DM-DS
Gemmiger	TNF-a	Gemmiger+Gastric cancer+MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.595	0.613	no	no	no	no	no	no	DM-DS
GDCA+stool	TNF-a	GDCA+stool+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.656	0.613	no	no	no	no	no	no	DM-DS
Methanobrevibacter	TNF-a	Methanobrevibacter-Alcoholism-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.629	0.613	no	no	no	no	no	no	DM-DS
Methanobrevibacter	TNF-a	Methanobrevibacter-Alcoholism-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.629	0.613	no	no	no	no	no	no	DM-DS
Methanobrevibacter	TNF-a	Methanobrevibacter-Alcoholism-IP-10+TNF-a	Indirect	Genus	serum_cytokines	0.629	0.613	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	TNF-a	L-Tyrosine+stool-nutriCA+stool-IL-9+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.613	no	no	no	no	no	no	DM-DS
CDCA+stool	TNF-a	CDCA+stool+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.663	0.613	no	no	no	no	no	no	DM-DS
CA+stool	TNF-a	CA+stool-LCA+stool+IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	DM-DS
CA+stool	TNF-a	CA+stool+GCA+stool-IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	DM-DS
CA+stool	TNF-a	CA+stool+nutriCA+stool-IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	DM-DS
CA+stool	TNF-a	CA+stool-iso-LCA+stool+IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	DM-DS
CA+stool	TNF-a	CA+stool+16:0/20:3-PC+blood+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	DM-DS
CA+stool	TNF-a	CA+stool+GDCA+stool+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	DM-DS
CA+stool	TNF-a	CA+stool+L-Tyrosine+blood+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	DM-DS
CA+stool	TNF-a	CA+stool+CDCA+stool+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	DM-DS
CA+stool	TNF-a	CA+stool-LCA+stool+MIP-1b+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	DM-DS
CA+stool	TNF-a	CA+stool+GCA+stool-MIP-1b+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	DM-DS
CA+stool	TNF-a	CA+stool-iso-LCA+stool+MIP-1b+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	DM-DS
HDCA+blood	TNF-a	HDCA+blood+iso-LCA+blood+MIP-1b+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.483	0.613	no	no	no	no	no	no	DM-DS
UDCA+stool	TNF-a	UDCA+stool+18:0/20:3-PI+blood-IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.266	0.613	no	no	no	no	no	no	DM-DS
UDCA+stool	TNF-a	UDCA+stool-GDCA+blood-IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.266	0.613	no	no	no	no	no	no	DM-DS
UDCA+stool	TNF-a	UDCA+stool+L-Tyrosine+blood+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.266	0.613	no	no	no	no	no	no	DM-DS
UDCA+stool	TNF-a	UDCA+stool+16:0/20:3-PC+blood+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.266	0.613	no	no	no	no	no	no	DM-DS
UDCA+stool	TNF-a	UDCA+stool-TDCA+blood-IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.266	0.613	no	no	no	no	no	no	DM-DS
UDCA+stool	TNF-a	UDCA+stool-iso-LCA+blood+MIP-1b+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.266	0.613	no	no	no	no	no	no	DM-DS
TDCA+stool	TNF-a	TDCA+stool-IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.963	0.613	no	no	no	no	no	no	DM-DS
TDCA+stool	TNF-a	TDCA+stool-MIP-1b+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.963	0.613	no	no	no	no	no	no	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	TNF-a	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2-TNF-a	Indirect	urine_cometabolism	serum_cytokines	0.973	0.613	no	no	no	no	no	no	DM-DS
Desulfovibrio	TNF-a	Desulfovibrio+Human T-cell leukemia virus 1 infection-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.27	0.613	no	no	no	no	no	no	DM-DS
Desulfovibrio	TNF-a	Desulfovibrio+Human cytomegalovirus infection-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.27	0.613	no	no	no	no	no	no	DM-DS
Desulfovibrio	TNF-a	Desulfovibrio+Human immunodeficiency virus 1 infection-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.27	0.613	no	no	no	no	no	no	DM-DS
Desulfovibrio	TNF-a	Desulfovibrio+Antigen processing and presentation-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.27	0.613	no	no	no	no	no	no	DM-DS
Desulfovibrio	TNF-a	Desulfovibrio+Herpes simplex virus 1 infection-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.27	0.613	no	no	no	no	no	no	DM-DS
Desulfovibrio	TNF-a	Desulfovibrio+Human T-cell leukemia virus 1 infection-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.27	0.613	no	no	no	no	no	no	DM-DS
Desulfovibrio	TNF-a	Desulfovibrio+Human cytomegalovirus infection-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.27	0.613	no	no	no	no	no	no	DM-DS
Desulfovibrio	TNF-a	Desulfovibrio+Human immunodeficiency virus 1 infection-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.27	0.613	no	no	no	no	no	no	DM-DS
Desulfovibrio	TNF-a	Desulfovibrio+Antigen processing and presentation-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.27	0.613	no	no	no	no	no	no	DM-DS
Desulfovibrio	TNF-a	Desulfovibrio+Herpes simplex virus 1 infection-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.27	0.613	no	no	no	no	no	no	DM-DS
Desulfovibrio	TNF-a	Desulfovibrio+Antigen processing and presentation+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.27	0.613	no	no	no	no	no	no	DM-DS
nutriCA+stool	TNF-a	nutriCA+stool-IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.481	0.613	no	no	no	no	no	no	DM-DS
Bilophila	TNF-a	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.528	0.613	no	no	no	no	no	no	DM-DS
Bilophila	TNF-a	Bilophila+Desulfovibrio+Human cytomegalovirus infection-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.528	0.613	no	no	no	no	no	no	DM-DS
Bilophila	TNF-a	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.528	0.613	no	no	no	no	no	no	DM-DS
Bilophila	TNF-a	Bilophila+Desulfovibrio+Antigen processing and presentation-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.528	0.613	no	no	no	no	no	no	DM-DS
Bilophila	TNF-a	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.528	0.613	no	no	no	no	no	no	DM-DS
Bilophila	TNF-a	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.528	0.613	no	no	no	no	no	no	DM-DS
Bilophila	TNF-a	Bilophila+Desulfovibrio+Human cytomegalovirus infection-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.528	0.613	no	no	no	no	no	no	DM-DS
Bilophila	TNF-a	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.528	0.613	no	no	no	no	no	no	DM-DS
Bilophila	TNF-a	Bilophila+Desulfovibrio+Antigen processing and presentation-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.528	0.613	no	no	no	no	no	no	DM-DS
Bilophila	TNF-a	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.528	0.613	no	no	no	no	no	no	DM-DS
Bilophila	TNF-a	Bilophila+Desulfovibrio+Antigen processing and presentation+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.528	0.613	no	no	no	no	no	no	DM-DS
GDCA+blood	TNF-a	GDCA+blood-IP-10+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.632	0.613	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	TNF-a	P-hydroxyhippuric acid+urine+Eotaxin+IL-9+TNF-a	Indirect	urine_cometabolism	serum_cytokines	0.436	0.613	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	TNF-a	P-hydroxyhippuric acid+urine+Eotaxin-IL-6-TNF-a	Indirect	urine_cometabolism	serum_cytokines	0.436	0.613	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	TNF-a	P-hydroxyhippuric acid+urine+Eotaxin+MIP-1b+TNF-a	Indirect	urine_cometabolism	serum_cytokines	0.436	0.613	no	no	no	no	no	no	DM-DS
acetic acid C2+blood	TNF-a	acetic acid C2+blood+d18:1-22:1-SM+blood+iso-LCA+blood+MIP-1b+TNF-a	Indirect	serum_scfa	serum_cytokines	0.000193	0.613	up	dn	no	no	no	no	DM-DS
acetic acid C2+blood	TNF-a	acetic acid C2+blood+d18:1-18:1-SM+blood+Homovanillic acid+urine-MIP-1b+TNF-a	Indirect	serum_scfa	serum_cytokines	0.000193	0.613	up	dn	no	no	no	no	DM-DS
acetic acid C2+blood	TNF-a	acetic acid C2+blood+d18:1-20:1-SM+blood+Homovanillic acid+urine-MIP-1b+TNF-a	Indirect	serum_scfa	serum_cytokines	0.000193	0.613	up	dn	no	no	no	no	DM-DS
acetic acid C2+blood	TNF-a	acetic acid C2+blood+d18:1-18:1-SM+blood+Homovanillic acid+urine-IP-10+TNF-a	Indirect	serum_scfa	serum_cytokines	0.000193	0.613	up	dn	no	no	no	no	DM-DS
acetic acid C2+blood	TNF-a	acetic acid C2+blood+d18:1-20:1-SM+blood+Homovanillic acid+urine-IP-10+TNF-a	Indirect	serum_scfa	serum_cytokines	0.000193	0.613	up	dn	no	no	no	no	DM-DS
acetic acid C2+blood	TNF-a	acetic acid C2+blood+d18:1-20:1-SM+blood-L-Tyrosine+blood+IP-10+TNF-a	Indirect	serum_scfa	serum_cytokines	0.000193	0.613	up	dn	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	TNF-a	isovaleric acid iso-C5+blood-L-Phenylalanine+blood+L-Tyrosine+blood+IP-10+TNF-a	Indirect	serum_scfa	serum_cytokines	0.117	0.613	no	no	no	no	no	no	DM-DS
Clostridium	TNF-a	Clostridium-MIP-1b+TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	DM-DS
Clostridium	TNF-a	Clostridium+IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	DM-DS
Clostridium	TNF-a	Clostridium-IL-9+TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	TNF-a	T-¦Á-MCA+stool-UDCA+stool-iso-LCA+blood+MIP-1b+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.48	0.613	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	TNF-a	T-¦Á-MCA+stool-UDCA+stool+18:0/20:3-PI+blood-IL-9+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.48	0.613	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	TNF-a	T-¦Á-MCA+stool-UDCA+stool-TDCA+blood-IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.48	0.613	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	TNF-a	T-¦Á-MCA+stool-UDCA+stool+L-Tyrosine+blood+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.48	0.613	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	TNF-a	T-¦Á-MCA+stool-UDCA+stool+16:0/20:3-PC+blood+IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.48	0.613	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	TNF-a	T-¦Á-MCA+stool-UDCA+stool-GDCA+blood-IP-10+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.48	0.613	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	TNF-a	12-ketoDCA+blood+IL-9+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.517	0.613	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	TNF-a	12-ketoDCA+blood+MIP-1b+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.517	0.613	no	no	no	no	no	no	DM-DS
Butyricicoccus	TNF-a	"Butyricicoccus+12,13-EPOME+blood+18:1/18:1-PE+blood-IL-9+TNF-a"	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	DM-DS
Butyricicoccus	TNF-a	Butyricicoccus-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6-TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	DM-DS
Blautia	MIP-1b	Blautia-MIP-1b	Direct	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+MAPK signaling pathway+Progesterone-mediated oocyte maturation+MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+Alistipes-Alcoholism-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+MAPK signaling pathway-Alcoholism-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+Alistipes+T cell receptor signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+MAPK signaling pathway+T cell receptor signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+Alistipes+Colorectal cancer+MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+MAPK signaling pathway-Antigen processing and presentation-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+MAPK signaling pathway-Human cytomegalovirus infection-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+Alistipes+Gastric cancer+MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides-16:0/18:2-PI+blood-Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+MAPK signaling pathway+Choline metabolism in cancer+MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+Alistipes-IL-6-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+MAPK signaling pathway-IL-6-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+TXB2+blood+Homovanillic acid+urine-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+20:0+blood-Homovanillic acid+urine-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+MAPK signaling pathway-Epstein-Barr virus infection-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides-L-Tyrosine+blood+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+d18:1-22:0-SM+blood+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides-TCA+stool+TDCA+stool-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+Alistipes+Platinum drug resistance+MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides-TCA+stool-IL-9+MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides-18:1/18:1-PE+blood-IL-9+MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+MAPK signaling pathway-Human immunodeficiency virus 1 infection-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+MAPK signaling pathway-Human T-cell leukemia virus 1 infection-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+Alistipes+Signaling pathways regulating pluripotency of stem cells+MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+MAPK signaling pathway-Leukocyte transendothelial migration-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1b	Parabacteroides+MAPK signaling pathway+p53 signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-DS
Dorea	MIP-1b	Dorea+GCA+stool-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	DM-DS
Dorea	MIP-1b	Dorea+Carbon metabolism-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	DM-DS
Dorea	MIP-1b	Dorea-Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+L-Alanine+blood-IL-1ra+IL-8-MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool-L-Phenylalanine+stool+Homovanillic acid+urine-MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-Phenylacetic acid+stool+TXB2+blood+Homovanillic acid+urine-MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool-TXB2+blood+Homovanillic acid+urine-MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-Phenylacetic acid+stool-16:0/20:3-PC+blood-Homovanillic acid+urine-MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool+16:0/20:3-PC+blood-Homovanillic acid+urine-MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-Phenylacetic acid+stool-20:3n6+blood-Homovanillic acid+urine-MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool+20:3n6+blood-Homovanillic acid+urine-MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-Phenylacetic acid+stool-18:1/18:1-PC+blood-Homovanillic acid+urine-MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool+18:1/18:1-PC+blood-Homovanillic acid+urine-MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-Phenylacetic acid+stool+d18:1-20:1-SM+blood+Homovanillic acid+urine-MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool-d18:1-20:1-SM+blood+Homovanillic acid+urine-MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-Phenylacetic acid+stool-UDCA+blood+Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-Phenylacetic acid+stool-16:0/18:2-PC+blood-GLCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool+16:0/18:2-PC+blood-GLCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-Phenylacetic acid+stool-16:0/18:1-PC+blood-GLCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool+16:0/18:1-PC+blood-GLCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool+16:1/18:2-PG+blood-GLCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-Phenylacetic acid+stool-18:0/16:0-PC+blood-GLCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-Phenylacetic acid+stool-18:1/16:0-PC+blood-GLCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool+18:1/16:0-PC+blood-GLCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-Phenylacetic acid+stool-Cystine+blood-GLCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool+Cystine+blood-GLCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-Phenylacetic acid+stool+d18:1-22:1-SM+blood+iso-LCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-d18:1-16:1-SM+blood+d18:1-22:1-SM+blood+iso-LCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-d18:1-14:0-SM+blood+d18:1-22:1-SM+blood+iso-LCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool+UDCA+stool-iso-LCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-Phenylacetic acid+stool-L-Tyrosine+blood+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool+L-Tyrosine+blood+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-Phenylacetic acid+stool-16:0/16:1-PC+blood+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool+16:0/16:1-PC+blood+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-Phenylacetic acid+stool-16:0/20:3-PC+blood+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool+GDCA+stool+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-d18:1-16:1-SM+blood+d18:1-22:0-SM+blood+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-d18:1-14:0-SM+blood+d18:1-22:0-SM+blood+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium-Phenylacetic acid+stool-20:3n6+blood+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool+20:3n6+blood+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1b	Faecalibacterium+GCDCA+stool+16:1/18:2-PG+blood-IL-9+MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-DS
TUDCA+blood	MIP-1b	TUDCA+blood-TXB2+blood+Homovanillic acid+urine-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.0282	0.632	no	no	dn	no	no	no	DM-DS
Bacteroides	MIP-1b	Bacteroides-Pathways in cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1b	Bacteroides-Chronic myeloid leukemia+MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1b	Bacteroides-Choline metabolism in cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1b	Bacteroides+Longevity regulating pathway - multiple species-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	DM-DS
Propionic acid+stool	MIP-1b	Propionic acid+stool-L-Tyrosine+blood+IP-10+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.632	dn	no	up	no	no	no	DM-DS
Propionic acid+stool	MIP-1b	Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.632	dn	no	up	no	no	no	DM-DS
Propionic acid+stool	MIP-1b	Propionic acid+stool+d18:1-20:1-SM+blood+Homovanillic acid+urine-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.632	dn	no	up	no	no	no	DM-DS
Propionic acid+stool	MIP-1b	Propionic acid+stool+d18:1-18:1-SM+blood+Homovanillic acid+urine-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.632	dn	no	up	no	no	no	DM-DS
[Ruminococcus]	MIP-1b	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+MIP-1b	Indirect	Genus	serum_cytokines	0.0679	0.632	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	MIP-1b	[Ruminococcus]-Progesterone-mediated oocyte maturation+MIP-1b	Indirect	Genus	serum_cytokines	0.0679	0.632	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	MIP-1b	[Ruminococcus]-ErbB signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.0679	0.632	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	MIP-1b	[Ruminococcus]-Gastric cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.0679	0.632	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	MIP-1b	[Ruminococcus]-Platinum drug resistance+MIP-1b	Indirect	Genus	serum_cytokines	0.0679	0.632	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	MIP-1b	[Ruminococcus]-Pathways in cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.0679	0.632	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	MIP-1b	[Ruminococcus]-Non-small cell lung cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.0679	0.632	no	no	dn	no	no	no	DM-DS
GUDCA+blood	MIP-1b	GUDCA+blood+UDCA+blood+Eotaxin+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.632	no	no	dn	no	no	no	DM-DS
UDCA+blood	MIP-1b	UDCA+blood+Eotaxin+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.0939	0.632	no	no	dn	no	no	no	DM-DS
Acetic acid+stool	MIP-1b	Acetic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.0656	0.632	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	MIP-1b	Acetic acid+stool-16:0/18:0-PS+blood-iso-LCA+blood+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.0656	0.632	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	MIP-1b	Acetic acid+stool-18:0/18:0-PS+blood-iso-LCA+blood+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.0656	0.632	dn	no	no	no	no	no	DM-DS
Alistipes	MIP-1b	Alistipes+T cell receptor signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	DM-DS
Alistipes	MIP-1b	Alistipes-Alcoholism-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	DM-DS
Alistipes	MIP-1b	Alistipes-IL-6-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	DM-DS
Alistipes	MIP-1b	Alistipes+Colorectal cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	DM-DS
Alistipes	MIP-1b	Alistipes+Signaling pathways regulating pluripotency of stem cells+MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	DM-DS
Alistipes	MIP-1b	Alistipes+Platinum drug resistance+MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	DM-DS
Alistipes	MIP-1b	Alistipes+Gastric cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	DM-DS
Butyricimonas	MIP-1b	Butyricimonas-Creatinine+blood-GLCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.17	0.632	no	no	no	no	no	no	DM-DS
Butyricimonas	MIP-1b	Butyricimonas-iso-DCA+blood-IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.17	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-GnRH signaling pathway+iso-LCA+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-GnRH signaling pathway+iso-LCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-d18:1-22:1-SM+blood+iso-LCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-GnRH signaling pathway+LCA+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-GnRH signaling pathway+DCA+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella+Roseburia+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-GnRH signaling pathway+Cushing syndrome+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-Renin secretion+Cushing syndrome+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-Inflammatory mediator regulation of TRP channels+Cushing syndrome+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-GnRH signaling pathway+Chemical carcinogenesis - receptor activation+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-Endocrine and other factor-regulated calcium reabsorption+Chemical carcinogenesis - receptor activation+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-GnRH signaling pathway+12-ketoDCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-GnRH signaling pathway-Epstein-Barr virus infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-Renin secretion-Chronic myeloid leukemia+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-Inflammatory mediator regulation of TRP channels-Chronic myeloid leukemia+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-Renin secretion-Choline metabolism in cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-GnRH signaling pathway-GCA+stool-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-Renin secretion-Non-small cell lung cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1b	Collinsella-GnRH signaling pathway-Herpes simplex virus 1 infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-DS
5-Hydroxytryptamine+urine	MIP-1b	5-Hydroxytryptamine+urine-Hippuric acid+urine-IL-6-MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.171	0.632	no	no	no	no	no	no	DM-DS
Sarcina	MIP-1b	Sarcina+Chronic myeloid leukemia+MIP-1b	Indirect	Genus	serum_cytokines	0.0703	0.632	no	no	no	no	no	no	DM-DS
Sarcina	MIP-1b	Sarcina+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.0703	0.632	no	no	no	no	no	no	DM-DS
Methanosphaera	MIP-1b	Methanosphaera-Roseburia+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.0703	0.632	no	no	no	no	no	no	DM-DS
iso-DCA+stool	MIP-1b	iso-DCA+stool+Propionic acid+stool-L-Tyrosine+blood+IP-10+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.632	no	no	no	no	no	no	DM-DS
iso-DCA+stool	MIP-1b	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.632	no	no	no	no	no	no	DM-DS
iso-DCA+stool	MIP-1b	iso-DCA+stool+Propionic acid+stool+d18:1-20:1-SM+blood+Homovanillic acid+urine-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.632	no	no	no	no	no	no	DM-DS
iso-DCA+stool	MIP-1b	iso-DCA+stool+Propionic acid+stool+d18:1-18:1-SM+blood+Homovanillic acid+urine-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.632	no	no	no	no	no	no	DM-DS
LCA+stool	MIP-1b	LCA+stool+MIP-1b	Direct	stool_bileacids	serum_cytokines	0.314	0.632	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1b	Akkermansia-Breast cancer+Gastric cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1b	Akkermansia-Longevity regulating pathway-Leukocyte transendothelial migration-MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1b	Akkermansia-Longevity regulating pathway-Regulation of actin cytoskeleton-MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1b	Akkermansia+P-hydroxyhippuric acid+urine+Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1b	Akkermansia-Longevity regulating pathway+Chemical carcinogenesis - receptor activation+MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1b	Akkermansia-Cytokine-cytokine receptor interaction+Longevity regulating pathway - multiple species-MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1b	Akkermansia-Longevity regulating pathway-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1b	Akkermansia-Breast cancer-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1b	Akkermansia-Longevity regulating pathway+Cushing syndrome+MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1b	Akkermansia-Cytokine-cytokine receptor interaction-Cushing syndrome+MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1b	Akkermansia-Cytokine-cytokine receptor interaction+Neuroactive ligand-receptor interaction-MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1b	Akkermansia-Longevity regulating pathway-GCA+stool-MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1b	Akkermansia+Proteoglycans in cancer-Choline metabolism in cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1b	Akkermansia-Longevity regulating pathway+Choline metabolism in cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1b	Akkermansia-Breast cancer+Choline metabolism in cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1b	Akkermansia-Cytokine-cytokine receptor interaction-Spinocerebellar ataxia+MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1b	Akkermansia-Cytokine-cytokine receptor interaction-Signaling pathways regulating pluripotency of stem cells+MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-DS
Bifidobacterium	MIP-1b	Bifidobacterium+Leukocyte transendothelial migration-MIP-1b	Indirect	Genus	serum_cytokines	0.105	0.632	no	dn	no	no	no	no	DM-DS
3-Hydroxytyramine hydrochloride+urine	MIP-1b	3-Hydroxytyramine hydrochloride+urine-Hippuric acid+urine-IL-6-MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.288	0.632	no	no	no	no	no	no	DM-DS
Ruminococcus	MIP-1b	Ruminococcus-Alcoholism-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	DM-DS
Ruminococcus	MIP-1b	Ruminococcus+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	DM-DS
GCDCA+blood	MIP-1b	GCDCA+blood-TXB2+blood+Homovanillic acid+urine-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.632	no	no	no	no	no	no	DM-DS
GCDCA+blood	MIP-1b	GCDCA+blood+L-Tyrosine+blood+IP-10+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.632	no	no	no	no	no	no	DM-DS
ACA+blood	MIP-1b	ACA+blood+EPA+blood+TXB2+blood+Homovanillic acid+urine-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.338	0.632	no	no	no	no	no	no	DM-DS
ACA+blood	MIP-1b	ACA+blood-decanoic acid C10+blood-TXB2+blood+Homovanillic acid+urine-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.338	0.632	no	no	no	no	no	no	DM-DS
ACA+blood	MIP-1b	ACA+blood+EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.338	0.632	no	no	no	no	no	no	DM-DS
DCA+stool	MIP-1b	DCA+stool+MIP-1b	Direct	stool_bileacids	serum_cytokines	0.195	0.632	no	no	no	no	no	no	DM-DS
Hippuric acid+urine	MIP-1b	Hippuric acid+urine-IL-6-MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.361	0.632	no	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1b	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.632	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1b	Butyric acid+stool+L-Citrulline+blood+Eotaxin+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.632	dn	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	MIP-1b	4-hydroxybenzoic acid+stool+TDCA+stool-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.632	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	MIP-1b	4-hydroxybenzoic acid+stool-LCA+stool+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.632	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	MIP-1b	4-hydroxybenzoic acid+stool-DCA+stool+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.632	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	MIP-1b	4-hydroxybenzoic acid+stool-iso-LCA+stool+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.632	no	dn	no	no	no	no	DM-DS
Turicibacter	MIP-1b	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-MIP-1b	Indirect	Genus	serum_cytokines	0.269	0.632	no	no	no	no	no	no	DM-DS
Turicibacter	MIP-1b	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-MIP-1b	Indirect	Genus	serum_cytokines	0.269	0.632	no	no	no	no	no	no	DM-DS
Turicibacter	MIP-1b	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-MIP-1b	Indirect	Genus	serum_cytokines	0.269	0.632	no	no	no	no	no	no	DM-DS
Turicibacter	MIP-1b	Turicibacter+Desulfovibrio+Antigen processing and presentation-MIP-1b	Indirect	Genus	serum_cytokines	0.269	0.632	no	no	no	no	no	no	DM-DS
Turicibacter	MIP-1b	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-MIP-1b	Indirect	Genus	serum_cytokines	0.269	0.632	no	no	no	no	no	no	DM-DS
GCA+blood	MIP-1b	GCA+blood+TDCA+blood-IP-10+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.16	0.632	no	no	no	no	no	no	DM-DS
ACA+stool	MIP-1b	ACA+stool-L-Tryptophan+stool+Homovanillic acid+urine-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.417	0.632	no	no	no	no	no	no	DM-DS
ACA+stool	MIP-1b	ACA+stool-L-Phenylalanine+stool+Homovanillic acid+urine-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.417	0.632	no	no	no	no	no	no	DM-DS
CDCA+blood	MIP-1b	CDCA+blood+UDCA+blood+Eotaxin+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.632	no	no	no	no	no	no	DM-DS
capric acid C6+blood	MIP-1b	capric acid C6+blood-HCA+blood-TXB2+blood+Homovanillic acid+urine-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.433	0.632	no	no	no	no	no	no	DM-DS
capric acid C6+blood	MIP-1b	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin+MIP-1b	Indirect	serum_scfa	serum_cytokines	0.433	0.632	no	no	no	no	no	no	DM-DS
Prevotella	MIP-1b	Prevotella+Choline metabolism in cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.287	0.632	no	no	no	no	no	no	DM-DS
TCA+blood	MIP-1b	TCA+blood+TUDCA+blood-TXB2+blood+Homovanillic acid+urine-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.339	0.632	no	no	no	no	no	no	DM-DS
iso-DCA+blood	MIP-1b	iso-DCA+blood-IP-10+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.38	0.632	no	no	no	no	no	no	DM-DS
HCA+stool	MIP-1b	HCA+stool-HDCA+stool+LCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.632	no	no	no	no	no	no	DM-DS
HCA+stool	MIP-1b	HCA+stool-HDCA+stool+IL-9+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.632	no	no	no	no	no	no	DM-DS
HCA+stool	MIP-1b	HCA+stool-HDCA+stool+Eotaxin+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.632	no	no	no	no	no	no	DM-DS
HCA+stool	MIP-1b	HCA+stool-HDCA+stool+iso-LCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.632	no	no	no	no	no	no	DM-DS
Roseburia	MIP-1b	Roseburia+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.495	0.632	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool-TDCA+stool-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool+LCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool+iso-LCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool+DCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool-GCA+stool-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	DM-DS
GLCA+blood	MIP-1b	GLCA+blood+MIP-1b	Direct	serum_bileacids	serum_cytokines	0.319	0.632	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	MIP-1b	L-Tryptophan+stool+Homovanillic acid+urine-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.632	no	no	no	no	no	no	DM-DS
CA+blood	MIP-1b	CA+blood+UDCA+blood+Eotaxin+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.606	0.632	no	no	no	no	no	no	DM-DS
CA+blood	MIP-1b	CA+blood+TDCA+blood-IP-10+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.606	0.632	no	no	no	no	no	no	DM-DS
GUDCA+stool	MIP-1b	GUDCA+stool+12-HEPE+blood-Cystine+blood-GLCA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0085	0.632	no	dn	no	no	no	no	DM-DS
GUDCA+stool	MIP-1b	GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0085	0.632	no	dn	no	no	no	no	DM-DS
GUDCA+stool	MIP-1b	GUDCA+stool+12-HEPE+blood-L-Tyrosine+blood+IP-10+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0085	0.632	no	dn	no	no	no	no	DM-DS
L-Phenylalanine+stool	MIP-1b	L-Phenylalanine+stool+Homovanillic acid+urine-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.632	no	no	no	no	no	no	DM-DS
butyric acid C4+blood	MIP-1b	butyric acid C4+blood+iso-LCA+blood+MIP-1b	Indirect	serum_scfa	serum_cytokines	0.407	0.632	no	no	no	no	no	no	DM-DS
GCA+stool	MIP-1b	GCA+stool-MIP-1b	Direct	stool_bileacids	serum_cytokines	0.0809	0.632	no	no	no	no	no	no	DM-DS
Coprococcus	MIP-1b	Coprococcus+L-Tyrosine+blood+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.612	0.632	no	no	no	no	no	no	DM-DS
Coprococcus	MIP-1b	Coprococcus+Roseburia+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.612	0.632	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1b	Oscillospira+Platinum drug resistance+MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1b	Oscillospira+Progesterone-mediated oocyte maturation+MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1b	Oscillospira-Human cytomegalovirus infection-MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1b	Oscillospira+Spliceosome+MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1b	Oscillospira+T cell receptor signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	DM-DS
HCA+blood	MIP-1b	HCA+blood-TXB2+blood+Homovanillic acid+urine-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.544	0.632	no	no	no	no	no	no	DM-DS
HCA+blood	MIP-1b	HCA+blood+UDCA+blood+Eotaxin+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.544	0.632	no	no	no	no	no	no	DM-DS
iso-LCA+stool	MIP-1b	iso-LCA+stool+MIP-1b	Direct	stool_bileacids	serum_cytokines	0.72	0.632	no	no	no	no	no	no	DM-DS
DCA+blood	MIP-1b	DCA+blood+nutriCA+blood+UDCA+blood+Eotaxin+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.632	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool+9-HODE+blood+butyric acid C4+blood+iso-LCA+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-d18:1-14:0-SM+blood+d18:1-22:1-SM+blood+iso-LCA+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-Cystine+blood-GLCA+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-14:0/18:2-PC+blood-Creatinine+blood-GLCA+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool+9-HODE+blood+AA+blood-IP-10+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Tyrosine+blood+IP-10+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-d18:1-14:0-SM+blood+d18:1-22:0-SM+blood+IP-10+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-14:0/18:2-PC+blood+24:0+blood-Homovanillic acid+urine-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	MIP-1b	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+MIP-1b"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.632	up	up	no	no	no	no	DM-DS
nutriCA+blood	MIP-1b	nutriCA+blood+UDCA+blood+Eotaxin+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.726	0.632	no	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+urine	MIP-1b	4-hydroxybenzoic acid+urine+Homovanillic acid+urine-MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.52	0.632	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1b	Indole-3-Acetic acid+stool-nutriCA+stool-iso-LCA+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.632	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1b	Indole-3-Acetic acid+stool-UDCA+stool-iso-LCA+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.632	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1b	Indole-3-Acetic acid+stool-nutriCA+stool-IL-9+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.632	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1b	TCA+stool+TDCA+stool-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1b	TCA+stool-IL-9+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-DS
HDCA+stool	MIP-1b	HDCA+stool+LCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.632	no	no	no	no	no	no	DM-DS
HDCA+stool	MIP-1b	HDCA+stool+IL-9+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.632	no	no	no	no	no	no	DM-DS
HDCA+stool	MIP-1b	HDCA+stool+Eotaxin+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.632	no	no	no	no	no	no	DM-DS
HDCA+stool	MIP-1b	HDCA+stool+iso-LCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.632	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1b	Lachnospira+Carbon metabolism-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1b	Lachnospira-p53 signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1b	Lachnospira-Chronic myeloid leukemia+MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1b	Lachnospira-Progesterone-mediated oocyte maturation+MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1b	Lachnospira-Platinum drug resistance+MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1b	Lachnospira-T cell receptor signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1b	Lachnospira+Regulation of actin cytoskeleton-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1b	Lachnospira-Spliceosome+MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1b	Lachnospira-Signaling pathways regulating pluripotency of stem cells+MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1b	Lachnospira+Leukocyte transendothelial migration-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1b	Lachnospira-ErbB signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1b	Lachnospira-Non-small cell lung cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1b	Lachnospira+Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-DS
Fusobacterium	MIP-1b	Fusobacterium-Intestinal immune network for IgA production-Progesterone-mediated oocyte maturation+MIP-1b	Indirect	Genus	serum_cytokines	0.628	0.632	no	no	no	no	no	no	DM-DS
Fusobacterium	MIP-1b	Fusobacterium-18:0/18:0-PC+blood+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.628	0.632	no	no	no	no	no	no	DM-DS
Fusobacterium	MIP-1b	Fusobacterium-16:0/20:3-PC+blood+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.628	0.632	no	no	no	no	no	no	DM-DS
Fusobacterium	MIP-1b	Fusobacterium-18:0/18:1-PC+blood+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.628	0.632	no	no	no	no	no	no	DM-DS
Fusobacterium	MIP-1b	Fusobacterium-16:0/20:3-PC+blood-Homovanillic acid+urine-MIP-1b	Indirect	Genus	serum_cytokines	0.628	0.632	no	no	no	no	no	no	DM-DS
Fusobacterium	MIP-1b	Fusobacterium+d18:1-18:1-SM+blood+Homovanillic acid+urine-MIP-1b	Indirect	Genus	serum_cytokines	0.628	0.632	no	no	no	no	no	no	DM-DS
Fusobacterium	MIP-1b	Fusobacterium-18:1/16:0-PC+blood-GLCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.628	0.632	no	no	no	no	no	no	DM-DS
Fusobacterium	MIP-1b	Fusobacterium-16:0/18:2-PC+blood-GLCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.628	0.632	no	no	no	no	no	no	DM-DS
Fusobacterium	MIP-1b	Fusobacterium-16:0/18:1-PC+blood-GLCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.628	0.632	no	no	no	no	no	no	DM-DS
Fusobacterium	MIP-1b	Fusobacterium-18:0/16:0-PC+blood-GLCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.628	0.632	no	no	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool+UDCA+stool-iso-LCA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool+L-Tyrosine+blood+IP-10+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool+20:3n6+blood+IP-10+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool+16:0/16:1-PC+blood+IP-10+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool+GDCA+stool+IP-10+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool+16:1/18:2-PG+blood-IL-9+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool+16:1/18:2-PG+blood-GLCA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool+18:1/16:0-PC+blood-GLCA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool+16:0/18:2-PC+blood-GLCA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool+16:0/18:1-PC+blood-GLCA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool+Cystine+blood-GLCA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool+20:3n6+blood-Homovanillic acid+urine-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool+16:0/20:3-PC+blood-Homovanillic acid+urine-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool+18:1/18:1-PC+blood-Homovanillic acid+urine-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool-L-Phenylalanine+stool+Homovanillic acid+urine-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool-TXB2+blood+Homovanillic acid+urine-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1b	GCDCA+stool-d18:1-20:1-SM+blood+Homovanillic acid+urine-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	MIP-1b	5-Hydroxytryptamine+stool-UDCA+stool-iso-LCA+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.632	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	MIP-1b	5-Hydroxytryptamine+stool-nutriCA+stool-iso-LCA+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.632	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	MIP-1b	5-Hydroxytryptamine+stool-nutriCA+stool-IL-9+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.632	dn	dn	no	no	no	no	DM-DS
Odoribacter	MIP-1b	Odoribacter-DCA+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.798	0.632	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1b	Odoribacter-iso-LCA+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.798	0.632	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1b	Odoribacter+GCA+stool-MIP-1b	Indirect	Genus	serum_cytokines	0.798	0.632	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1b	Odoribacter+Antigen processing and presentation-MIP-1b	Indirect	Genus	serum_cytokines	0.798	0.632	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1b	Odoribacter-Cushing syndrome+MIP-1b	Indirect	Genus	serum_cytokines	0.798	0.632	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1b	Odoribacter+Neuroactive ligand-receptor interaction-MIP-1b	Indirect	Genus	serum_cytokines	0.798	0.632	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1b	Odoribacter-Chemical carcinogenesis - receptor activation+MIP-1b	Indirect	Genus	serum_cytokines	0.798	0.632	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1b	Odoribacter-LCA+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.798	0.632	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1b	Odoribacter+Carbon metabolism-MIP-1b	Indirect	Genus	serum_cytokines	0.798	0.632	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1b	Odoribacter+Longevity regulating pathway - multiple species-MIP-1b	Indirect	Genus	serum_cytokines	0.798	0.632	no	no	no	no	no	no	DM-DS
Actinomyces	MIP-1b	Actinomyces+Coprococcus+L-Tyrosine+blood+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.621	0.632	no	no	no	no	no	no	DM-DS
Actinomyces	MIP-1b	Actinomyces+Coprococcus+Roseburia+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.621	0.632	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1b	Isobutyric acid+stool+L-Phenylalanine+stool+Homovanillic acid+urine-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.632	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1b	Isobutyric acid+stool-nutriCA+stool-iso-LCA+blood+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.632	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1b	Isobutyric acid+stool-UDCA+stool-iso-LCA+blood+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.632	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1b	Isobutyric acid+stool-nutriCA+stool-IL-9+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.632	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	MIP-1b	2-hydroxyphenylacetic acid+urine+Homovanillic acid+urine-MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.763	0.632	no	no	no	no	no	no	DM-DS
Kynurenic acid+stool	MIP-1b	Kynurenic acid+stool+L-Phenylalanine+stool+Homovanillic acid+urine-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.632	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	MIP-1b	Kynurenic acid+stool-nutriCA+stool-iso-LCA+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.632	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	MIP-1b	Kynurenic acid+stool-nutriCA+stool-IL-9+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.632	dn	dn	no	no	no	no	DM-DS
Caproic acid+stool	MIP-1b	Caproic acid+stool-GCA+stool-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.882	0.632	no	no	no	no	no	no	DM-DS
Caproic acid+stool	MIP-1b	Caproic acid+stool-TDCA+stool-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.882	0.632	no	no	no	no	no	no	DM-DS
Eggerthella	MIP-1b	Eggerthella-iso-LCA+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.912	0.632	no	no	no	no	no	no	DM-DS
Anaerotruncus	MIP-1b	Anaerotruncus-Ruminococcus-Alcoholism-MIP-1b	Indirect	Genus	serum_cytokines	0.904	0.632	no	no	no	no	no	no	DM-DS
Anaerotruncus	MIP-1b	Anaerotruncus-Ruminococcus+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.904	0.632	no	no	no	no	no	no	DM-DS
Anaerostipes	MIP-1b	Anaerostipes-Alcoholism-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	DM-DS
Anaerostipes	MIP-1b	Anaerostipes-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	DM-DS
Anaerostipes	MIP-1b	Anaerostipes+Spliceosome+MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	DM-DS
Anaerostipes	MIP-1b	Anaerostipes+Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	DM-DS
Anaerostipes	MIP-1b	Anaerostipes-IL-6-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	DM-DS
TUDCA+stool	MIP-1b	TUDCA+stool-14:0/18:2-PC+blood+24:0+blood-Homovanillic acid+urine-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-DS
TUDCA+stool	MIP-1b	TUDCA+stool-14:0/18:2-PC+blood-Creatinine+blood-GLCA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-DS
TUDCA+stool	MIP-1b	TUDCA+stool+9-HODE+blood+butyric acid C4+blood+iso-LCA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-DS
TUDCA+stool	MIP-1b	TUDCA+stool-d18:1-14:0-SM+blood+d18:1-22:1-SM+blood+iso-LCA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-DS
TUDCA+stool	MIP-1b	TUDCA+stool+9-HODE+blood+AA+blood-IP-10+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-DS
TUDCA+stool	MIP-1b	TUDCA+stool-d18:1-14:0-SM+blood+d18:1-22:0-SM+blood+IP-10+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	MIP-1b	Isovaleric acid+stool-UDCA+stool-iso-LCA+blood+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.632	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	MIP-1b	Isovaleric acid+stool+L-Phenylalanine+stool+Homovanillic acid+urine-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.632	no	no	no	no	no	no	DM-DS
Paraprevotella	MIP-1b	Paraprevotella+IP-10+MIP-1b	Indirect	Genus	serum_cytokines	0.118	0.632	no	no	no	no	no	no	DM-DS
Paraprevotella	MIP-1b	Paraprevotella-Biosynthesis of amino acids-MIP-1b	Indirect	Genus	serum_cytokines	0.118	0.632	no	no	no	no	no	no	DM-DS
Homovanillic acid+urine	MIP-1b	Homovanillic acid+urine-MIP-1b	Direct	urine_cometabolism	serum_cytokines	0.45	0.632	no	no	no	no	no	no	DM-DS
TDCA+blood	MIP-1b	TDCA+blood-IP-10+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.155	0.632	no	up	no	no	no	no	DM-DS
iso-LCA+blood	MIP-1b	iso-LCA+blood+MIP-1b	Direct	serum_bileacids	serum_cytokines	0.507	0.632	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	MIP-1b	¦Ø-MCA+stool+CDCA+stool-LCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.919	0.632	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	MIP-1b	¦Ø-MCA+stool+CDCA+stool+GCA+stool-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.919	0.632	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	MIP-1b	¦Ø-MCA+stool-L-Phenylalanine+stool+Homovanillic acid+urine-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.919	0.632	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	MIP-1b	¦Ø-MCA+stool-L-Tryptophan+stool+Homovanillic acid+urine-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.919	0.632	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	MIP-1b	¦Ø-MCA+stool+CDCA+stool-iso-LCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.919	0.632	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	MIP-1b	¦Ø-MCA+stool+GDCA+stool+IP-10+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.919	0.632	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	MIP-1b	¦Ø-MCA+stool+CDCA+stool+IP-10+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.919	0.632	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool-16:0/18:2-PC+blood-GLCA+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool-16:0/18:1-PC+blood-GLCA+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool-18:1/16:0-PC+blood-GLCA+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool-Cystine+blood-GLCA+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool-18:0/16:0-PC+blood-GLCA+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool-16:0/20:3-PC+blood+IP-10+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool-16:0/16:1-PC+blood+IP-10+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool-L-Tyrosine+blood+IP-10+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool-20:3n6+blood+IP-10+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool+d18:1-22:1-SM+blood+iso-LCA+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool-16:0/20:3-PC+blood-Homovanillic acid+urine-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool+d18:1-20:1-SM+blood+Homovanillic acid+urine-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool-18:1/18:1-PC+blood-Homovanillic acid+urine-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool+TXB2+blood+Homovanillic acid+urine-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool-20:3n6+blood-Homovanillic acid+urine-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool-UDCA+blood+Eotaxin+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-DS
Gemmiger	MIP-1b	Gemmiger+Signaling pathways regulating pluripotency of stem cells+MIP-1b	Indirect	Genus	serum_cytokines	0.595	0.632	no	no	no	no	no	no	DM-DS
Gemmiger	MIP-1b	Gemmiger+Pathways in cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.595	0.632	no	no	no	no	no	no	DM-DS
Gemmiger	MIP-1b	Gemmiger+ErbB signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.595	0.632	no	no	no	no	no	no	DM-DS
Gemmiger	MIP-1b	Gemmiger+Colorectal cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.595	0.632	no	no	no	no	no	no	DM-DS
Gemmiger	MIP-1b	Gemmiger+Gastric cancer+MIP-1b	Indirect	Genus	serum_cytokines	0.595	0.632	no	no	no	no	no	no	DM-DS
GDCA+stool	MIP-1b	GDCA+stool+IP-10+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.632	no	no	no	no	no	no	DM-DS
Methanobrevibacter	MIP-1b	Methanobrevibacter-Alcoholism-MIP-1b	Indirect	Genus	serum_cytokines	0.629	0.632	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	MIP-1b	L-Tyrosine+stool-nutriCA+stool-iso-LCA+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.632	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	MIP-1b	L-Tyrosine+stool-nutriCA+stool-IL-9+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.632	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	MIP-1b	L-Tyrosine+stool-UDCA+blood+Eotaxin+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.632	no	no	no	no	no	no	DM-DS
CDCA+stool	MIP-1b	CDCA+stool+GCA+stool-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-DS
CDCA+stool	MIP-1b	CDCA+stool-LCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-DS
CDCA+stool	MIP-1b	CDCA+stool-iso-LCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-DS
CDCA+stool	MIP-1b	CDCA+stool+IP-10+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-DS
CA+stool	MIP-1b	CA+stool-LCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	DM-DS
CA+stool	MIP-1b	CA+stool+GCA+stool-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	DM-DS
CA+stool	MIP-1b	CA+stool-iso-LCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	DM-DS
HDCA+blood	MIP-1b	HDCA+blood+iso-LCA+blood+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.483	0.632	no	no	no	no	no	no	DM-DS
UDCA+stool	MIP-1b	UDCA+stool-iso-LCA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.632	no	no	no	no	no	no	DM-DS
TDCA+stool	MIP-1b	TDCA+stool-MIP-1b	Direct	stool_bileacids	serum_cytokines	0.963	0.632	no	no	no	no	no	no	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	MIP-1b	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2-MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.973	0.632	no	no	no	no	no	no	DM-DS
Desulfovibrio	MIP-1b	Desulfovibrio+Human T-cell leukemia virus 1 infection-MIP-1b	Indirect	Genus	serum_cytokines	0.27	0.632	no	no	no	no	no	no	DM-DS
Desulfovibrio	MIP-1b	Desulfovibrio+Human cytomegalovirus infection-MIP-1b	Indirect	Genus	serum_cytokines	0.27	0.632	no	no	no	no	no	no	DM-DS
Desulfovibrio	MIP-1b	Desulfovibrio+Human immunodeficiency virus 1 infection-MIP-1b	Indirect	Genus	serum_cytokines	0.27	0.632	no	no	no	no	no	no	DM-DS
Desulfovibrio	MIP-1b	Desulfovibrio+Antigen processing and presentation-MIP-1b	Indirect	Genus	serum_cytokines	0.27	0.632	no	no	no	no	no	no	DM-DS
Desulfovibrio	MIP-1b	Desulfovibrio+Herpes simplex virus 1 infection-MIP-1b	Indirect	Genus	serum_cytokines	0.27	0.632	no	no	no	no	no	no	DM-DS
nutriCA+stool	MIP-1b	nutriCA+stool-iso-LCA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.632	no	no	no	no	no	no	DM-DS
nutriCA+stool	MIP-1b	nutriCA+stool-IL-9+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.632	no	no	no	no	no	no	DM-DS
Bilophila	MIP-1b	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-MIP-1b	Indirect	Genus	serum_cytokines	0.528	0.632	no	no	no	no	no	no	DM-DS
Bilophila	MIP-1b	Bilophila+Desulfovibrio+Human cytomegalovirus infection-MIP-1b	Indirect	Genus	serum_cytokines	0.528	0.632	no	no	no	no	no	no	DM-DS
Bilophila	MIP-1b	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-MIP-1b	Indirect	Genus	serum_cytokines	0.528	0.632	no	no	no	no	no	no	DM-DS
Bilophila	MIP-1b	Bilophila+Desulfovibrio+Antigen processing and presentation-MIP-1b	Indirect	Genus	serum_cytokines	0.528	0.632	no	no	no	no	no	no	DM-DS
Bilophila	MIP-1b	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-MIP-1b	Indirect	Genus	serum_cytokines	0.528	0.632	no	no	no	no	no	no	DM-DS
GDCA+blood	MIP-1b	GDCA+blood+iso-LCA+blood+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.632	0.632	no	no	no	no	no	no	DM-DS
GDCA+blood	MIP-1b	GDCA+blood-IP-10+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.632	0.632	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	MIP-1b	P-hydroxyhippuric acid+urine+Eotaxin+MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.436	0.632	no	no	no	no	no	no	DM-DS
acetic acid C2+blood	MIP-1b	acetic acid C2+blood+d18:1-22:1-SM+blood+iso-LCA+blood+MIP-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.632	up	dn	no	no	no	no	DM-DS
acetic acid C2+blood	MIP-1b	acetic acid C2+blood+d18:1-18:1-SM+blood+Homovanillic acid+urine-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.632	up	dn	no	no	no	no	DM-DS
acetic acid C2+blood	MIP-1b	acetic acid C2+blood+d18:1-20:1-SM+blood+Homovanillic acid+urine-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.632	up	dn	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	MIP-1b	isovaleric acid iso-C5+blood-L-Phenylalanine+blood+L-Tyrosine+blood+IP-10+MIP-1b	Indirect	serum_scfa	serum_cytokines	0.117	0.632	no	no	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	MIP-1b	isovaleric acid iso-C5+blood+n3+blood+TXB2+blood+Homovanillic acid+urine-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.117	0.632	no	no	no	no	no	no	DM-DS
Clostridium	MIP-1b	Clostridium-MIP-1b	Direct	Genus	serum_cytokines	0.925	0.632	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-UDCA+stool-iso-LCA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	MIP-1b	12-ketoDCA+blood+MIP-1b	Direct	serum_bileacids	serum_cytokines	0.517	0.632	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1b	"Butyricicoccus+12,13-EPOME+blood-20:0+blood-Homovanillic acid+urine-MIP-1b"	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1b	Butyricicoccus-18:2/20:4-PC+blood+20:0+blood-Homovanillic acid+urine-MIP-1b	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1b	"Butyricicoccus+12,13-EPOME+blood+9,10-EPOME+blood+Homovanillic acid+urine-MIP-1b"	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1b	"Butyricicoccus+12,13-EPOME+blood-d18:1-20:1-SM+blood+Homovanillic acid+urine-MIP-1b"	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1b	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood-Eotaxin+MIP-1b"	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1b	"Butyricicoccus+12,13-EPOME+blood+18:1/18:1-PE+blood-IL-9+MIP-1b"	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1b	Butyricicoccus-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6-MIP-1b	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1b	Butyricicoccus-18:2/20:4-PC+blood-IL-1ra+IL-8-MIP-1b	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1b	"Butyricicoccus+12,13-EPOME+blood-HDCA+blood+iso-LCA+blood+MIP-1b"	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1b	"Butyricicoccus+12,13-EPOME+blood-20:0-LPC+blood+iso-LCA+blood+MIP-1b"	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1b	Butyricicoccus-18:2/20:4-PC+blood+20:0-LPC+blood+iso-LCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1b	"Butyricicoccus+12,13-EPOME+blood-d18:1-22:1-SM+blood+iso-LCA+blood+MIP-1b"	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1b	"Butyricicoccus+12,13-EPOME+blood-20:0-LPC+blood+GLCA+blood+MIP-1b"	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1b	Butyricicoccus-18:2/20:4-PC+blood+20:0-LPC+blood+GLCA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	DM-DS
Blautia	IL-9	Blautia-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	1.36E-05	0.906	up	dn	dn	no	no	no	DM-DS
Blautia	IL-9	Blautia+GCA+stool-IL-9	Indirect	Genus	serum_cytokines	1.36E-05	0.906	up	dn	dn	no	no	no	DM-DS
Parabacteroides	IL-9	Parabacteroides-TCA+stool-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	DM-DS
Parabacteroides	IL-9	Parabacteroides-18:1/18:1-PE+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	DM-DS
Dorea	IL-9	Dorea+GCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-DS
Dorea	IL-9	Dorea-Eotaxin+IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-DS
Faecalibacterium	IL-9	Faecalibacterium+GCDCA+stool+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.0039	0.906	no	dn	dn	no	no	no	DM-DS
Bacteroides	IL-9	Bacteroides-16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	DM-DS
Propionic acid+stool	IL-9	Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+IL-9	Indirect	stool_scfa	serum_cytokines	0.0436	0.906	dn	no	up	no	no	no	DM-DS
[Ruminococcus]	IL-9	[Ruminococcus]-Progesterone-mediated oocyte maturation+IL-9	Indirect	Genus	serum_cytokines	0.0679	0.906	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-9	[Ruminococcus]+18:1/18:1-PE+blood-IL-9	Indirect	Genus	serum_cytokines	0.0679	0.906	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-9	[Ruminococcus]-ErbB signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.0679	0.906	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-9	[Ruminococcus]-Gastric cancer+IL-9	Indirect	Genus	serum_cytokines	0.0679	0.906	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-9	[Ruminococcus]-Platinum drug resistance+IL-9	Indirect	Genus	serum_cytokines	0.0679	0.906	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-9	[Ruminococcus]-Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.0679	0.906	no	no	dn	no	no	no	DM-DS
GUDCA+blood	IL-9	GUDCA+blood+UDCA+blood+Eotaxin+IL-9	Indirect	serum_bileacids	serum_cytokines	0.0766	0.906	no	no	dn	no	no	no	DM-DS
UDCA+blood	IL-9	UDCA+blood+Eotaxin+IL-9	Indirect	serum_bileacids	serum_cytokines	0.0939	0.906	no	no	dn	no	no	no	DM-DS
Acetic acid+stool	IL-9	Acetic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+IL-9	Indirect	stool_scfa	serum_cytokines	0.0656	0.906	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	IL-9	Acetic acid+stool-14:0+blood+18:1/18:1-PE+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.0656	0.906	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	IL-9	Acetic acid+stool+18:1-LPC+blood-18:1/18:1-PE+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.0656	0.906	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	IL-9	Acetic acid+stool-18:0+blood+18:1/18:2-PG+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.0656	0.906	dn	no	no	no	no	no	DM-DS
Alistipes	IL-9	Alistipes+T cell receptor signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.0114	0.906	no	up	no	no	no	no	DM-DS
Alistipes	IL-9	Alistipes+nutriCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.0114	0.906	no	up	no	no	no	no	DM-DS
Alistipes	IL-9	Alistipes-Alcoholism-IL-9	Indirect	Genus	serum_cytokines	0.0114	0.906	no	up	no	no	no	no	DM-DS
Alistipes	IL-9	Alistipes-IL-6-IL-9	Indirect	Genus	serum_cytokines	0.0114	0.906	no	up	no	no	no	no	DM-DS
Alistipes	IL-9	Alistipes+Platinum drug resistance+IL-9	Indirect	Genus	serum_cytokines	0.0114	0.906	no	up	no	no	no	no	DM-DS
Alistipes	IL-9	Alistipes+Gastric cancer+IL-9	Indirect	Genus	serum_cytokines	0.0114	0.906	no	up	no	no	no	no	DM-DS
Butyricimonas	IL-9	Butyricimonas+Cholinergic synapse-TCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.17	0.906	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-9	Butyricimonas+18:0+blood+18:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.17	0.906	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-9	Butyricimonas-Creatinine+blood-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.17	0.906	no	no	no	no	no	no	DM-DS
Collinsella	IL-9	Collinsella-GnRH signaling pathway+iso-LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-DS
Collinsella	IL-9	Collinsella-GnRH signaling pathway+LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-DS
Collinsella	IL-9	Collinsella-GnRH signaling pathway+Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-DS
Collinsella	IL-9	Collinsella-Endocrine and other factor-regulated calcium reabsorption+Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-DS
Collinsella	IL-9	Collinsella-GnRH signaling pathway+12-ketoDCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-DS
Collinsella	IL-9	Collinsella-GnRH signaling pathway-Epstein-Barr virus infection-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-DS
Collinsella	IL-9	Collinsella-GnRH signaling pathway-GCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-DS
Collinsella	IL-9	Collinsella-GnRH signaling pathway+HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-DS
Collinsella	IL-9	Collinsella-Endocrine and other factor-regulated calcium reabsorption+HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-DS
Collinsella	IL-9	Collinsella-GnRH signaling pathway-18:0/20:3-PI+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-DS
Collinsella	IL-9	Collinsella-Renin secretion-Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-DS
Collinsella	IL-9	Collinsella-GnRH signaling pathway-Herpes simplex virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-DS
5-Hydroxytryptamine+urine	IL-9	5-Hydroxytryptamine+urine-Hippuric acid+urine-IL-6-IL-9	Indirect	urine_cometabolism	serum_cytokines	0.171	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Viral carcinogenesis+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Osteoclast differentiation+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Cellular senescence+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Human papillomavirus infection+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Apoptosis+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Toll-like receptor signaling pathway+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Fc epsilon RI signaling pathway+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+C-type lectin receptor signaling pathway+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Prolactin signaling pathway+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Osteoclast differentiation+T cell receptor signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+NF-kappa B signaling pathway+T cell receptor signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Toll-like receptor signaling pathway+T cell receptor signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+RIG-I-like receptor signaling pathway+T cell receptor signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+C-type lectin receptor signaling pathway+T cell receptor signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Th17 cell differentiation+T cell receptor signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-Glucagon signaling pathway+Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Cellular senescence-Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-Amphetamine addiction+Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-GnRH signaling pathway+Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-Aldosterone synthesis and secretion+Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-Dopaminergic synapse-GCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Cellular senescence+GCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-GnRH signaling pathway-GCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-Aldosterone synthesis and secretion-GCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Cellular senescence+Antigen processing and presentation-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Acute myeloid leukemia+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Human papillomavirus infection+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+NF-kappa B signaling pathway+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Insulin resistance+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-Circadian entrainment-Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Neurotrophin signaling pathway+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Chronic myeloid leukemia+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Toll-like receptor signaling pathway+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+RIG-I-like receptor signaling pathway+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Fc epsilon RI signaling pathway+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Prostate cancer+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+C-type lectin receptor signaling pathway+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Prolactin signaling pathway+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+TNF signaling pathway+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+B cell receptor signaling pathway+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Cellular senescence+Epstein-Barr virus infection-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-GnRH signaling pathway-Epstein-Barr virus infection-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Cellular senescence+Human immunodeficiency virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Human papillomavirus infection+Human immunodeficiency virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Cellular senescence+Human cytomegalovirus infection-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Cellular senescence+Herpes simplex virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-GnRH signaling pathway-Herpes simplex virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Cellular senescence+Human T-cell leukemia virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Cellular senescence-LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-GnRH signaling pathway+LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-Aldosterone synthesis and secretion+LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Cellular senescence-iso-LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-GnRH signaling pathway+iso-LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Apoptosis+18:0/18:2-PI+blood-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Viral carcinogenesis-HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-Glucagon signaling pathway+HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Osteoclast differentiation-HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-Dopaminergic synapse+HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Cellular senescence-HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Human papillomavirus infection-HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Apoptosis-HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-Amphetamine addiction+HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-GnRH signaling pathway+HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-Aldosterone synthesis and secretion+HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Fc epsilon RI signaling pathway-HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Prolactin signaling pathway-HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+NF-kappa B signaling pathway-Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-Circadian entrainment+Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Neurotrophin signaling pathway-Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Toll-like receptor signaling pathway-Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+RIG-I-like receptor signaling pathway-Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Fc epsilon RI signaling pathway-Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+C-type lectin receptor signaling pathway-Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+TNF signaling pathway-Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+B cell receptor signaling pathway-Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Insulin resistance+Gastric cancer+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Chronic myeloid leukemia+Gastric cancer+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-GnRH signaling pathway+12-ketoDCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina-GnRH signaling pathway-18:0/20:3-PI+blood-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Sarcina	IL-9	Sarcina+Th17 cell differentiation-Alcoholism-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-9	Methanosphaera-Roseburia+16:0/16:1-PC+blood+18:0/20:3-PI+blood-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-9	Methanosphaera-Roseburia+GCDCA+stool+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-9	Methanosphaera-Roseburia+16:0/16:1-PC+blood+18:1/18:1-PE+blood-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-9	Methanosphaera-Roseburia+16:0/18:2-PI+blood+18:1/18:1-PE+blood-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-9	Methanosphaera-Roseburia+16:0/16:1-PC+blood+18:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-9	Methanosphaera-Roseburia+16:0/18:2-PI+blood-Eotaxin+IL-9	Indirect	Genus	serum_cytokines	0.0703	0.906	no	no	no	no	no	no	DM-DS
iso-DCA+stool	IL-9	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+IL-9	Indirect	stool_bileacids	serum_cytokines	0.155	0.906	no	no	no	no	no	no	DM-DS
LCA+stool	IL-9	LCA+stool+IL-9	Direct	stool_bileacids	serum_cytokines	0.314	0.906	no	no	no	no	no	no	DM-DS
Akkermansia	IL-9	Akkermansia-Breast cancer+Gastric cancer+IL-9	Indirect	Genus	serum_cytokines	0.23	0.906	no	no	no	no	no	no	DM-DS
Akkermansia	IL-9	Akkermansia-Longevity regulating pathway-Leukocyte transendothelial migration-IL-9	Indirect	Genus	serum_cytokines	0.23	0.906	no	no	no	no	no	no	DM-DS
Akkermansia	IL-9	Akkermansia-Cholinergic synapse-TCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.23	0.906	no	no	no	no	no	no	DM-DS
Akkermansia	IL-9	Akkermansia-Longevity regulating pathway-Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.23	0.906	no	no	no	no	no	no	DM-DS
Akkermansia	IL-9	Akkermansia+P-hydroxyhippuric acid+urine+Eotaxin+IL-9	Indirect	Genus	serum_cytokines	0.23	0.906	no	no	no	no	no	no	DM-DS
Akkermansia	IL-9	Akkermansia-Longevity regulating pathway+Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.23	0.906	no	no	no	no	no	no	DM-DS
Akkermansia	IL-9	Akkermansia-Longevity regulating pathway-GCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.23	0.906	no	no	no	no	no	no	DM-DS
Bifidobacterium	IL-9	Bifidobacterium+Leukocyte transendothelial migration-IL-9	Indirect	Genus	serum_cytokines	0.105	0.906	no	dn	no	no	no	no	DM-DS
3-Hydroxytyramine hydrochloride+urine	IL-9	3-Hydroxytyramine hydrochloride+urine-Hippuric acid+urine-IL-6-IL-9	Indirect	urine_cometabolism	serum_cytokines	0.288	0.906	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-9	Ruminococcus+nutriCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-9	Ruminococcus-Alcoholism-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	DM-DS
GCDCA+blood	IL-9	GCDCA+blood+GUDCA+blood+UDCA+blood+Eotaxin+IL-9	Indirect	serum_bileacids	serum_cytokines	0.31	0.906	no	no	no	no	no	no	DM-DS
GCDCA+blood	IL-9	GCDCA+blood+HCA+blood+UDCA+blood+Eotaxin+IL-9	Indirect	serum_bileacids	serum_cytokines	0.31	0.906	no	no	no	no	no	no	DM-DS
GCDCA+blood	IL-9	GCDCA+blood+L-Alanine+blood-IL-1ra+IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.31	0.906	no	no	no	no	no	no	DM-DS
ACA+blood	IL-9	ACA+blood+EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin+IL-9	Indirect	serum_bileacids	serum_cytokines	0.338	0.906	no	no	no	no	no	no	DM-DS
DCA+stool	IL-9	DCA+stool+iso-LCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.195	0.906	no	no	no	no	no	no	DM-DS
DCA+stool	IL-9	DCA+stool-TDCA+stool-IL-9	Indirect	stool_bileacids	serum_cytokines	0.195	0.906	no	no	no	no	no	no	DM-DS
DCA+stool	IL-9	DCA+stool+HDCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.195	0.906	no	no	no	no	no	no	DM-DS
DCA+stool	IL-9	DCA+stool+LCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.195	0.906	no	no	no	no	no	no	DM-DS
DCA+stool	IL-9	DCA+stool-GCA+stool-IL-9	Indirect	stool_bileacids	serum_cytokines	0.195	0.906	no	no	no	no	no	no	DM-DS
Hippuric acid+urine	IL-9	Hippuric acid+urine-IL-6-IL-9	Indirect	urine_cometabolism	serum_cytokines	0.361	0.906	no	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-9	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+IL-9	Indirect	stool_scfa	serum_cytokines	0.102	0.906	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-9	Butyric acid+stool+L-Citrulline+blood+Eotaxin+IL-9	Indirect	stool_scfa	serum_cytokines	0.102	0.906	dn	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	IL-9	4-hydroxybenzoic acid+stool+TDCA+stool-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.906	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	IL-9	4-hydroxybenzoic acid+stool-LCA+stool+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.906	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	IL-9	4-hydroxybenzoic acid+stool-iso-LCA+stool+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.906	no	dn	no	no	no	no	DM-DS
Turicibacter	IL-9	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.269	0.906	no	no	no	no	no	no	DM-DS
Turicibacter	IL-9	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-IL-9	Indirect	Genus	serum_cytokines	0.269	0.906	no	no	no	no	no	no	DM-DS
Turicibacter	IL-9	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.269	0.906	no	no	no	no	no	no	DM-DS
Turicibacter	IL-9	Turicibacter+Desulfovibrio+Antigen processing and presentation-IL-9	Indirect	Genus	serum_cytokines	0.269	0.906	no	no	no	no	no	no	DM-DS
Turicibacter	IL-9	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.269	0.906	no	no	no	no	no	no	DM-DS
GCA+blood	IL-9	GCA+blood+TDCA+blood-IL-1ra+IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.16	0.906	no	no	no	no	no	no	DM-DS
GCA+blood	IL-9	GCA+blood+HCA+blood+UDCA+blood+Eotaxin+IL-9	Indirect	serum_bileacids	serum_cytokines	0.16	0.906	no	no	no	no	no	no	DM-DS
ACA+stool	IL-9	ACA+stool-Kynurenic acid+stool-nutriCA+stool-IL-9	Indirect	stool_bileacids	serum_cytokines	0.417	0.906	no	no	no	no	no	no	DM-DS
CDCA+blood	IL-9	CDCA+blood+UDCA+blood+Eotaxin+IL-9	Indirect	serum_bileacids	serum_cytokines	0.506	0.906	no	no	no	no	no	no	DM-DS
capric acid C6+blood	IL-9	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin+IL-9	Indirect	serum_scfa	serum_cytokines	0.433	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	"Prevotella+Growth hormone synthesis, secretion and action-Herpes simplex virus 1 infection-IL-9"	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Endocrine resistance-Herpes simplex virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	"Prevotella+Growth hormone synthesis, secretion and action-Epstein-Barr virus infection-IL-9"	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Endocrine resistance-Epstein-Barr virus infection-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	"Prevotella+Growth hormone synthesis, secretion and action-Human immunodeficiency virus 1 infection-IL-9"	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Endocrine resistance-Human immunodeficiency virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	"Prevotella+Growth hormone synthesis, secretion and action-Human cytomegalovirus infection-IL-9"	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Endocrine resistance-Human cytomegalovirus infection-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	"Prevotella+Growth hormone synthesis, secretion and action-Human T-cell leukemia virus 1 infection-IL-9"	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Proteasome+Human T-cell leukemia virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Endocrine resistance-Human T-cell leukemia virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Amoebiasis+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Prolactin signaling pathway+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Tight junction+Antigen processing and presentation-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+FoxO signaling pathway-Antigen processing and presentation-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Proteasome+Antigen processing and presentation-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Endocrine resistance-Antigen processing and presentation-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Glycolysis / Gluconeogenesis-ErbB signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Proteasome-ErbB signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+18:0+blood+18:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Tight junction-Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Glycolysis / Gluconeogenesis-Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Bacterial invasion of epithelial cells-Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	"Prevotella+Growth hormone synthesis, secretion and action+Chemical carcinogenesis - receptor activation+IL-9"	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Proteasome-Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Endocrine resistance+Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Glycolysis / Gluconeogenesis+GCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	"Prevotella+Growth hormone synthesis, secretion and action-GCA+stool-IL-9"	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Proteasome+GCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Endocrine resistance-GCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Choline metabolism in cancer-GCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Tight junction-iso-LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Bacterial invasion of epithelial cells-iso-LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	"Prevotella+Growth hormone synthesis, secretion and action+iso-LCA+stool+IL-9"	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Proteasome-iso-LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Endocrine resistance+iso-LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Choline metabolism in cancer+iso-LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Glycolysis / Gluconeogenesis+nutriCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	"Prevotella+Growth hormone synthesis, secretion and action-nutriCA+stool-IL-9"	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Proteasome+nutriCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Phospholipase D signaling pathway-nutriCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Tight junction+IL-6-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Bacterial invasion of epithelial cells+IL-6-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+FoxO signaling pathway-IL-6-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Hippuric acid+urine-IL-6-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Focal adhesion+IL-6-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Tight junction-Gastric cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Glycolysis / Gluconeogenesis-Gastric cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Bacterial invasion of epithelial cells-Gastric cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+FoxO signaling pathway+Gastric cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	"Prevotella+Growth hormone synthesis, secretion and action+Gastric cancer+IL-9"	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Focal adhesion-Gastric cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Breast cancer+Gastric cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Endocrine resistance+Gastric cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Nicotinate and nicotinamide metabolism+Lysosome-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Endocrine resistance-Lysosome-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Endocrine resistance+12-ketoDCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Glycolysis / Gluconeogenesis-p53 signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+FoxO signaling pathway+p53 signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Endocrine resistance+p53 signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Prolactin signaling pathway-HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Tight junction-LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Bacterial invasion of epithelial cells-LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	"Prevotella+Growth hormone synthesis, secretion and action+LCA+stool+IL-9"	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Proteasome-LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Endocrine resistance+LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Glycolysis / Gluconeogenesis-Platinum drug resistance+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Tight junction+Leukocyte transendothelial migration-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Glycolysis / Gluconeogenesis+Leukocyte transendothelial migration-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+FoxO signaling pathway-Leukocyte transendothelial migration-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Autophagy - animal-Leukocyte transendothelial migration-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Hippo signaling pathway+Leukocyte transendothelial migration-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Focal adhesion+Leukocyte transendothelial migration-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Transcriptional misregulation in cancer+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Tight junction-Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Glycolysis / Gluconeogenesis-Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Bacterial invasion of epithelial cells-Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Acute myeloid leukemia+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+FoxO signaling pathway+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	"Prevotella+Growth hormone synthesis, secretion and action+Non-small cell lung cancer+IL-9"	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Autophagy - animal+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Amoebiasis+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Hippo signaling pathway-Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Focal adhesion-Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Proteasome-Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Prolactin signaling pathway+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Phospholipase D signaling pathway+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Measles+Eotaxin+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Tight junction+TDCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Bacterial invasion of epithelial cells+TDCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Proteasome+TDCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Choline metabolism in cancer-TDCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Tight junction-T cell receptor signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+FoxO signaling pathway+T cell receptor signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Autophagy - animal+T cell receptor signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Hippo signaling pathway-T cell receptor signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Focal adhesion-T cell receptor signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Tight junction+TCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Bacterial invasion of epithelial cells+TCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+FoxO signaling pathway-TCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Hypertrophic cardiomyopathy+TCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Hippo signaling pathway+TCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Focal adhesion+TCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Tight junction+Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Glycolysis / Gluconeogenesis+Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+FoxO signaling pathway-Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Autophagy - animal-Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Hippo signaling pathway+Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Focal adhesion+Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Proteasome+Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+Phospholipase D signaling pathway-Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+14:0+blood+18:1/18:1-PE+blood-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Measles-18:1/18:1-PE+blood-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Tight junction-Progesterone-mediated oocyte maturation+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella+FoxO signaling pathway+Progesterone-mediated oocyte maturation+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
Prevotella	IL-9	Prevotella-Focal adhesion-Progesterone-mediated oocyte maturation+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-DS
iso-DCA+blood	IL-9	iso-DCA+blood-IL-1ra+IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.38	0.906	no	no	no	no	no	no	DM-DS
iso-DCA+blood	IL-9	iso-DCA+blood+L-Citrulline+blood+Eotaxin+IL-9	Indirect	serum_bileacids	serum_cytokines	0.38	0.906	no	no	no	no	no	no	DM-DS
HCA+stool	IL-9	HCA+stool-HDCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.155	0.906	no	no	no	no	no	no	DM-DS
Roseburia	IL-9	Roseburia+16:0/16:1-PC+blood+18:0/20:3-PI+blood-IL-9	Indirect	Genus	serum_cytokines	0.495	0.906	no	no	no	no	no	no	DM-DS
Roseburia	IL-9	Roseburia+GCDCA+stool+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.495	0.906	no	no	no	no	no	no	DM-DS
Roseburia	IL-9	Roseburia+16:0/16:1-PC+blood+18:1/18:1-PE+blood-IL-9	Indirect	Genus	serum_cytokines	0.495	0.906	no	no	no	no	no	no	DM-DS
Roseburia	IL-9	Roseburia+16:0/18:2-PI+blood+18:1/18:1-PE+blood-IL-9	Indirect	Genus	serum_cytokines	0.495	0.906	no	no	no	no	no	no	DM-DS
Roseburia	IL-9	Roseburia+16:0/16:1-PC+blood+18:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.495	0.906	no	no	no	no	no	no	DM-DS
Roseburia	IL-9	Roseburia+16:0/18:2-PI+blood-Eotaxin+IL-9	Indirect	Genus	serum_cytokines	0.495	0.906	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	IL-9	12-ketoDCA+stool-TDCA+stool-IL-9	Indirect	stool_bileacids	serum_cytokines	0.505	0.906	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	IL-9	12-ketoDCA+stool+LCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.505	0.906	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	IL-9	12-ketoDCA+stool+iso-LCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.505	0.906	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	IL-9	12-ketoDCA+stool+HDCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.505	0.906	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	IL-9	12-ketoDCA+stool-GCA+stool-IL-9	Indirect	stool_bileacids	serum_cytokines	0.505	0.906	no	no	no	no	no	no	DM-DS
GLCA+blood	IL-9	GLCA+blood+IL-9	Direct	serum_bileacids	serum_cytokines	0.319	0.906	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-9	L-Tryptophan+stool+L-Tyrosine+stool-nutriCA+stool-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.557	0.906	no	no	no	no	no	no	DM-DS
CA+blood	IL-9	CA+blood+UDCA+blood+Eotaxin+IL-9	Indirect	serum_bileacids	serum_cytokines	0.606	0.906	no	no	no	no	no	no	DM-DS
GUDCA+stool	IL-9	GUDCA+stool+12-HEPE+blood-Cystine+blood-GLCA+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.0085	0.906	no	dn	no	no	no	no	DM-DS
GUDCA+stool	IL-9	GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin+IL-9	Indirect	stool_bileacids	serum_cytokines	0.0085	0.906	no	dn	no	no	no	no	DM-DS
L-Phenylalanine+stool	IL-9	L-Phenylalanine+stool+L-Tyrosine+stool-nutriCA+stool-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.398	0.906	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	IL-9	L-Phenylalanine+stool-16:0/20:3-PC+blood+18:0/20:3-PI+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.398	0.906	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	IL-9	L-Phenylalanine+stool-UDCA+blood+Eotaxin+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.398	0.906	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	IL-9	L-Phenylalanine+stool-18:0+blood+18:1/18:2-PG+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.398	0.906	no	no	no	no	no	no	DM-DS
GCA+stool	IL-9	GCA+stool-IL-9	Direct	stool_bileacids	serum_cytokines	0.0809	0.906	no	no	no	no	no	no	DM-DS
Coprococcus	IL-9	Coprococcus+Roseburia+GCDCA+stool+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-DS
Coprococcus	IL-9	Coprococcus+Roseburia+16:0/16:1-PC+blood+18:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-DS
Coprococcus	IL-9	Coprococcus-14:0/18:2-PC+blood+18:0+blood+18:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-DS
Coprococcus	IL-9	Coprococcus+Roseburia+16:0/16:1-PC+blood+18:0/20:3-PI+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-DS
Coprococcus	IL-9	Coprococcus-14:0/18:2-PC+blood+16:0/18:3-PC+blood-18:0/20:3-PI+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-DS
Coprococcus	IL-9	Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin+IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-DS
Coprococcus	IL-9	Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-DS
Coprococcus	IL-9	Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin+IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-DS
Coprococcus	IL-9	Coprococcus+Roseburia+16:0/18:2-PI+blood+18:1/18:1-PE+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-DS
Coprococcus	IL-9	Coprococcus+Roseburia+16:0/16:1-PC+blood+18:1/18:1-PE+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-DS
Coprococcus	IL-9	Coprococcus+16:0/16:0-PC+blood+18:1/16:0-PC+blood-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-DS
Coprococcus	IL-9	Coprococcus+16:0/16:0-PC+blood+16:0/18:2-PC+blood-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-DS
Coprococcus	IL-9	Coprococcus+16:0/16:0-PC+blood+16:0/18:1-PC+blood-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-DS
Coprococcus	IL-9	Coprococcus-14:0/18:2-PC+blood-Creatinine+blood-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-DS
Coprococcus	IL-9	Coprococcus+16:0/16:0-PC+blood+18:0/16:0-PC+blood-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-DS
Coprococcus	IL-9	Coprococcus+16:0/16:0-PC+blood+5-HETE+blood-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-DS
Oscillospira	IL-9	Oscillospira+Platinum drug resistance+IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	DM-DS
Oscillospira	IL-9	Oscillospira+Progesterone-mediated oocyte maturation+IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	DM-DS
Oscillospira	IL-9	Oscillospira-Human cytomegalovirus infection-IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	DM-DS
Oscillospira	IL-9	Oscillospira+Spliceosome+IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	DM-DS
Oscillospira	IL-9	Oscillospira+T cell receptor signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	DM-DS
HCA+blood	IL-9	HCA+blood+UDCA+blood+Eotaxin+IL-9	Indirect	serum_bileacids	serum_cytokines	0.544	0.906	no	no	no	no	no	no	DM-DS
iso-LCA+stool	IL-9	iso-LCA+stool+IL-9	Direct	stool_bileacids	serum_cytokines	0.72	0.906	no	no	no	no	no	no	DM-DS
DCA+blood	IL-9	DCA+blood+nutriCA+blood+UDCA+blood+Eotaxin+IL-9	Indirect	serum_bileacids	serum_cytokines	0.122	0.906	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-9	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood-18:0/20:3-PI+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.33	0.906	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-9	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-14:0/18:2-PC+blood+18:0+blood+18:1/18:2-PG+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.33	0.906	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-9	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.33	0.906	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-9	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-Cystine+blood-GLCA+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.33	0.906	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-9	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-14:0/18:2-PC+blood-Creatinine+blood-GLCA+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.33	0.906	no	no	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-9	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-9"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.906	up	up	no	no	no	no	DM-DS
nutriCA+blood	IL-9	nutriCA+blood+UDCA+blood+Eotaxin+IL-9	Indirect	serum_bileacids	serum_cytokines	0.726	0.906	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IL-9	Indole-3-Acetic acid+stool-nutriCA+stool-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.304	0.906	no	no	no	no	no	no	DM-DS
TCA+stool	IL-9	TCA+stool-IL-9	Direct	stool_bileacids	serum_cytokines	0.458	0.906	no	no	no	no	no	no	DM-DS
HDCA+stool	IL-9	HDCA+stool+IL-9	Direct	stool_bileacids	serum_cytokines	0.176	0.906	no	no	no	no	no	no	DM-DS
Lachnospira	IL-9	Lachnospira+TCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-DS
Lachnospira	IL-9	Lachnospira-p53 signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-DS
Lachnospira	IL-9	Lachnospira-Progesterone-mediated oocyte maturation+IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-DS
Lachnospira	IL-9	Lachnospira-Platinum drug resistance+IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-DS
Lachnospira	IL-9	Lachnospira-T cell receptor signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-DS
Lachnospira	IL-9	Lachnospira+Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-DS
Lachnospira	IL-9	Lachnospira-Spliceosome+IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-DS
Lachnospira	IL-9	Lachnospira+Leukocyte transendothelial migration-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-DS
Lachnospira	IL-9	Lachnospira-ErbB signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-DS
Lachnospira	IL-9	Lachnospira-Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-9	Fusobacterium-Intestinal immune network for IgA production-Progesterone-mediated oocyte maturation+IL-9	Indirect	Genus	serum_cytokines	0.628	0.906	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-9	Fusobacterium-18:0/18:0-PC+blood+18:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.628	0.906	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-9	Fusobacterium-18:0/18:1-PC+blood+18:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.628	0.906	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-9	Fusobacterium-Intestinal immune network for IgA production-HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.628	0.906	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-9	Fusobacterium-16:0/20:3-PC+blood+18:0/20:3-PI+blood-IL-9	Indirect	Genus	serum_cytokines	0.628	0.906	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-9	Fusobacterium-18:1/16:0-PC+blood-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.628	0.906	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-9	Fusobacterium-16:0/18:2-PC+blood-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.628	0.906	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-9	Fusobacterium-16:0/18:1-PC+blood-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.628	0.906	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-9	Fusobacterium-18:0/16:0-PC+blood-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.628	0.906	no	no	no	no	no	no	DM-DS
GCDCA+stool	IL-9	GCDCA+stool+16:1/18:2-PG+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.0471	0.906	no	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-9	5-Hydroxytryptamine+stool-nutriCA+stool-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.906	dn	dn	no	no	no	no	DM-DS
Odoribacter	IL-9	Odoribacter-iso-LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	DM-DS
Odoribacter	IL-9	Odoribacter+GCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	DM-DS
Odoribacter	IL-9	Odoribacter+Antigen processing and presentation-IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	DM-DS
Odoribacter	IL-9	Odoribacter-HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	DM-DS
Odoribacter	IL-9	Odoribacter-Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	DM-DS
Odoribacter	IL-9	Odoribacter-LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	DM-DS
Actinomyces	IL-9	Actinomyces+Coprococcus+Roseburia+GCDCA+stool+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.621	0.906	no	no	no	no	no	no	DM-DS
Actinomyces	IL-9	Actinomyces+Coprococcus+Roseburia+16:0/16:1-PC+blood+18:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.621	0.906	no	no	no	no	no	no	DM-DS
Actinomyces	IL-9	Actinomyces+Coprococcus-14:0/18:2-PC+blood+18:0+blood+18:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.621	0.906	no	no	no	no	no	no	DM-DS
Actinomyces	IL-9	Actinomyces+Coprococcus+Roseburia+16:0/16:1-PC+blood+18:0/20:3-PI+blood-IL-9	Indirect	Genus	serum_cytokines	0.621	0.906	no	no	no	no	no	no	DM-DS
Actinomyces	IL-9	Actinomyces+Coprococcus-14:0/18:2-PC+blood+16:0/18:3-PC+blood-18:0/20:3-PI+blood-IL-9	Indirect	Genus	serum_cytokines	0.621	0.906	no	no	no	no	no	no	DM-DS
Actinomyces	IL-9	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin+IL-9	Indirect	Genus	serum_cytokines	0.621	0.906	no	no	no	no	no	no	DM-DS
Actinomyces	IL-9	Actinomyces+Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin+IL-9	Indirect	Genus	serum_cytokines	0.621	0.906	no	no	no	no	no	no	DM-DS
Actinomyces	IL-9	Actinomyces+Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin+IL-9	Indirect	Genus	serum_cytokines	0.621	0.906	no	no	no	no	no	no	DM-DS
Actinomyces	IL-9	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood+18:1/18:1-PE+blood-IL-9	Indirect	Genus	serum_cytokines	0.621	0.906	no	no	no	no	no	no	DM-DS
Actinomyces	IL-9	Actinomyces+Coprococcus+Roseburia+16:0/16:1-PC+blood+18:1/18:1-PE+blood-IL-9	Indirect	Genus	serum_cytokines	0.621	0.906	no	no	no	no	no	no	DM-DS
Actinomyces	IL-9	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:1/16:0-PC+blood-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.621	0.906	no	no	no	no	no	no	DM-DS
Actinomyces	IL-9	Actinomyces+Coprococcus+16:0/16:0-PC+blood+16:0/18:2-PC+blood-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.621	0.906	no	no	no	no	no	no	DM-DS
Actinomyces	IL-9	Actinomyces+Coprococcus+16:0/16:0-PC+blood+16:0/18:1-PC+blood-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.621	0.906	no	no	no	no	no	no	DM-DS
Actinomyces	IL-9	Actinomyces+Coprococcus-14:0/18:2-PC+blood-Creatinine+blood-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.621	0.906	no	no	no	no	no	no	DM-DS
Actinomyces	IL-9	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:0/16:0-PC+blood-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.621	0.906	no	no	no	no	no	no	DM-DS
Actinomyces	IL-9	Actinomyces+Coprococcus+16:0/16:0-PC+blood+5-HETE+blood-GLCA+blood+IL-9	Indirect	Genus	serum_cytokines	0.621	0.906	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IL-9	Isobutyric acid+stool-nutriCA+stool-IL-9	Indirect	stool_scfa	serum_cytokines	0.408	0.906	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	IL-9	"2-hydroxyphenylacetic acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-9"	Indirect	urine_cometabolism	serum_cytokines	0.763	0.906	no	no	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-9	Kynurenic acid+stool-nutriCA+stool-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.037	0.906	dn	dn	no	no	no	no	DM-DS
Caproic acid+stool	IL-9	Caproic acid+stool-TCA+stool-IL-9	Indirect	stool_scfa	serum_cytokines	0.882	0.906	no	no	no	no	no	no	DM-DS
Caproic acid+stool	IL-9	Caproic acid+stool-GCA+stool-IL-9	Indirect	stool_scfa	serum_cytokines	0.882	0.906	no	no	no	no	no	no	DM-DS
Caproic acid+stool	IL-9	Caproic acid+stool-TDCA+stool-IL-9	Indirect	stool_scfa	serum_cytokines	0.882	0.906	no	no	no	no	no	no	DM-DS
Eggerthella	IL-9	Eggerthella+nutriCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.912	0.906	no	no	no	no	no	no	DM-DS
Eggerthella	IL-9	Eggerthella-iso-LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.912	0.906	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-9	Anaerotruncus-Ruminococcus+nutriCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.904	0.906	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-9	Anaerotruncus-Ruminococcus-Alcoholism-IL-9	Indirect	Genus	serum_cytokines	0.904	0.906	no	no	no	no	no	no	DM-DS
Anaerostipes	IL-9	Anaerostipes-Alcoholism-IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	DM-DS
Anaerostipes	IL-9	Anaerostipes+Spliceosome+IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	DM-DS
Anaerostipes	IL-9	Anaerostipes+Eotaxin+IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	DM-DS
Anaerostipes	IL-9	Anaerostipes-IL-6-IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-9	TUDCA+stool-14:0/18:2-PC+blood-Creatinine+blood-GLCA+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.241	0.906	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-9	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood-18:0/20:3-PI+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.241	0.906	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-9	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood+18:1/18:2-PG+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.241	0.906	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IL-9	Isovaleric acid+stool-UDCA+stool+18:0/20:3-PI+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.343	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Olfactory transduction-Gastric cancer+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Cell cycle+Gastric cancer+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Epithelial cell signaling in Helicobacter pylori infection+Human cytomegalovirus infection-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-IL-17 signaling pathway+Human cytomegalovirus infection-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Ribosome biogenesis in eukaryotes-Human cytomegalovirus infection-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Cell cycle-Human cytomegalovirus infection-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Epithelial cell signaling in Helicobacter pylori infection+18:0/18:2-PI+blood-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Fc epsilon RI signaling pathway-Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Hippo signaling pathway+Regulation of actin cytoskeleton-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-IL-17 signaling pathway+IL-6-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Ribosome biogenesis in eukaryotes-IL-6-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Cell cycle-IL-6-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-IL-17 signaling pathway-Eotaxin+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-IL-17 signaling pathway-Progesterone-mediated oocyte maturation+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Ribosome biogenesis in eukaryotes+Progesterone-mediated oocyte maturation+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Cell cycle+Progesterone-mediated oocyte maturation+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Wnt signaling pathway-Alcoholism-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-cGMP-PKG signaling pathway+Alcoholism-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Protein processing in endoplasmic reticulum-Alcoholism-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Olfactory transduction+Alcoholism-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+RNA degradation-Alcoholism-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-GABAergic synapse+Alcoholism-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Ribosome biogenesis in eukaryotes-Alcoholism-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Cell cycle-Alcoholism-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-cGMP-PKG signaling pathway-Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Fc gamma R-mediated phagocytosis-Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Biosynthesis of amino acids-Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Olfactory transduction-Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-IL-17 signaling pathway-Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Ribosome biogenesis in eukaryotes+Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Cell cycle+Chemical carcinogenesis - receptor activation+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Ribosome biogenesis in eukaryotes+Spliceosome+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-cGMP-PKG signaling pathway+Lysosome-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Protein processing in endoplasmic reticulum-Lysosome-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Biosynthesis of amino acids+Lysosome-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-PPAR signaling pathway+Lysosome-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Nicotinate and nicotinamide metabolism+Lysosome-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+RNA degradation-Lysosome-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Arginine and proline metabolism+Lysosome-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Ribosome biogenesis in eukaryotes-Lysosome-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Cell cycle-Lysosome-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Ribosome biogenesis in eukaryotes+p53 signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Ribosome biogenesis in eukaryotes-Epstein-Barr virus infection-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Cell cycle-Epstein-Barr virus infection-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Ribosome biogenesis in eukaryotes-Leukocyte transendothelial migration-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Hippo signaling pathway+Leukocyte transendothelial migration-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-cGMP-PKG signaling pathway-HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Fc gamma R-mediated phagocytosis-HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Biosynthesis of amino acids-HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-PPAR signaling pathway-HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Fc epsilon RI signaling pathway-HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Peroxisome-HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-IL-17 signaling pathway-HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Cell cycle+HDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Ribosome biogenesis in eukaryotes-Human immunodeficiency virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Cell cycle-Human immunodeficiency virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Cell cycle-Antigen processing and presentation-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Cell cycle-Human T-cell leukemia virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Fc gamma R-mediated phagocytosis-LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Biosynthesis of amino acids-LCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Arrhythmogenic right ventricular cardiomyopathy+TCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Hippo signaling pathway+TCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Adipocytokine signaling pathway+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Fc epsilon RI signaling pathway+Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Hippo signaling pathway-Non-small cell lung cancer+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Wnt signaling pathway-16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Protein processing in endoplasmic reticulum-16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Fc epsilon RI signaling pathway+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Epithelial cell signaling in Helicobacter pylori infection+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+RNA degradation-16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-IL-17 signaling pathway+16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Cell cycle-16:1/18:2-PG+blood-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Biosynthesis of amino acids+GCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-Peroxisome+GCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella-PPAR signaling pathway+T cell receptor signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-9	Paraprevotella+Hippo signaling pathway-T cell receptor signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-DS
TDCA+blood	IL-9	TDCA+blood-IL-1ra+IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.155	0.906	no	up	no	no	no	no	DM-DS
¦Ø-MCA+stool	IL-9	¦Ø-MCA+stool+CDCA+stool-LCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.919	0.906	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	IL-9	¦Ø-MCA+stool+CDCA+stool+GCA+stool-IL-9	Indirect	stool_bileacids	serum_cytokines	0.919	0.906	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	IL-9	¦Ø-MCA+stool+CDCA+stool+18:0/20:3-PI+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.919	0.906	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	IL-9	¦Ø-MCA+stool-L-Tyrosine+stool-nutriCA+stool-IL-9	Indirect	stool_bileacids	serum_cytokines	0.919	0.906	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	IL-9	¦Ø-MCA+stool-Isobutyric acid+stool-nutriCA+stool-IL-9	Indirect	stool_bileacids	serum_cytokines	0.919	0.906	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	IL-9	¦Ø-MCA+stool+CDCA+stool+nutriCA+stool-IL-9	Indirect	stool_bileacids	serum_cytokines	0.919	0.906	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	IL-9	¦Ø-MCA+stool+CDCA+stool-iso-LCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.919	0.906	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-14:0+blood+18:1/18:1-PE+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-16:0/16:1-PC+blood+18:1/18:1-PE+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-16:0/20:3-PC+blood+18:0/20:3-PI+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-16:0/16:1-PC+blood+18:0/20:3-PI+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-16:0/18:2-PC+blood-GLCA+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-16:0/18:1-PC+blood-GLCA+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-18:1/16:0-PC+blood-GLCA+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-Cystine+blood-GLCA+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-18:0/16:0-PC+blood-GLCA+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-18:0+blood+18:1/18:2-PG+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-16:0/16:1-PC+blood+18:1/18:2-PG+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-18:1/18:1-PC+blood+18:1/18:2-PG+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-UDCA+blood+Eotaxin+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	DM-DS
Gemmiger	IL-9	Gemmiger+ErbB signaling pathway+IL-9	Indirect	Genus	serum_cytokines	0.595	0.906	no	no	no	no	no	no	DM-DS
Gemmiger	IL-9	Gemmiger+Gastric cancer+IL-9	Indirect	Genus	serum_cytokines	0.595	0.906	no	no	no	no	no	no	DM-DS
GDCA+stool	IL-9	GDCA+stool+16:0/18:1-PC+blood-GLCA+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.656	0.906	no	no	no	no	no	no	DM-DS
GDCA+stool	IL-9	GDCA+stool+UDCA+stool+18:0/20:3-PI+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.656	0.906	no	no	no	no	no	no	DM-DS
GDCA+stool	IL-9	GDCA+stool+16:0/20:3-PC+blood+18:0/20:3-PI+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.656	0.906	no	no	no	no	no	no	DM-DS
GDCA+stool	IL-9	GDCA+stool-Indole-3-Acetic acid+stool-nutriCA+stool-IL-9	Indirect	stool_bileacids	serum_cytokines	0.656	0.906	no	no	no	no	no	no	DM-DS
GDCA+stool	IL-9	GDCA+stool-Isobutyric acid+stool-nutriCA+stool-IL-9	Indirect	stool_bileacids	serum_cytokines	0.656	0.906	no	no	no	no	no	no	DM-DS
Methanobrevibacter	IL-9	Methanobrevibacter-Alcoholism-IL-9	Indirect	Genus	serum_cytokines	0.629	0.906	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IL-9	L-Tyrosine+stool-nutriCA+stool-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.44	0.906	no	no	no	no	no	no	DM-DS
CDCA+stool	IL-9	CDCA+stool+GCA+stool-IL-9	Indirect	stool_bileacids	serum_cytokines	0.663	0.906	no	no	no	no	no	no	DM-DS
CDCA+stool	IL-9	CDCA+stool+nutriCA+stool-IL-9	Indirect	stool_bileacids	serum_cytokines	0.663	0.906	no	no	no	no	no	no	DM-DS
CDCA+stool	IL-9	CDCA+stool+18:0/20:3-PI+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.663	0.906	no	no	no	no	no	no	DM-DS
CDCA+stool	IL-9	CDCA+stool-LCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.663	0.906	no	no	no	no	no	no	DM-DS
CDCA+stool	IL-9	CDCA+stool-iso-LCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.663	0.906	no	no	no	no	no	no	DM-DS
CA+stool	IL-9	CA+stool-LCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.827	0.906	no	no	no	no	no	no	DM-DS
CA+stool	IL-9	CA+stool+GCA+stool-IL-9	Indirect	stool_bileacids	serum_cytokines	0.827	0.906	no	no	no	no	no	no	DM-DS
CA+stool	IL-9	CA+stool+nutriCA+stool-IL-9	Indirect	stool_bileacids	serum_cytokines	0.827	0.906	no	no	no	no	no	no	DM-DS
CA+stool	IL-9	CA+stool-iso-LCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.827	0.906	no	no	no	no	no	no	DM-DS
HDCA+blood	IL-9	HDCA+blood+Hypotaurine+blood-IL-1ra+IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.483	0.906	no	no	no	no	no	no	DM-DS
HDCA+blood	IL-9	HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin+IL-9	Indirect	serum_bileacids	serum_cytokines	0.483	0.906	no	no	no	no	no	no	DM-DS
UDCA+stool	IL-9	UDCA+stool+18:0/20:3-PI+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.266	0.906	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-9	TDCA+stool-IL-9	Direct	stool_bileacids	serum_cytokines	0.963	0.906	no	no	no	no	no	no	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	IL-9	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2-IL-9	Indirect	urine_cometabolism	serum_cytokines	0.973	0.906	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-9	Desulfovibrio+Human T-cell leukemia virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.27	0.906	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-9	Desulfovibrio+Human cytomegalovirus infection-IL-9	Indirect	Genus	serum_cytokines	0.27	0.906	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-9	Desulfovibrio+Human immunodeficiency virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.27	0.906	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-9	Desulfovibrio+Antigen processing and presentation-IL-9	Indirect	Genus	serum_cytokines	0.27	0.906	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-9	Desulfovibrio+Herpes simplex virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.27	0.906	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-9	nutriCA+stool-IL-9	Direct	stool_bileacids	serum_cytokines	0.481	0.906	no	no	no	no	no	no	DM-DS
Bilophila	IL-9	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.528	0.906	no	no	no	no	no	no	DM-DS
Bilophila	IL-9	Bilophila+Desulfovibrio+Human cytomegalovirus infection-IL-9	Indirect	Genus	serum_cytokines	0.528	0.906	no	no	no	no	no	no	DM-DS
Bilophila	IL-9	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.528	0.906	no	no	no	no	no	no	DM-DS
Bilophila	IL-9	Bilophila+Desulfovibrio+Antigen processing and presentation-IL-9	Indirect	Genus	serum_cytokines	0.528	0.906	no	no	no	no	no	no	DM-DS
Bilophila	IL-9	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-IL-9	Indirect	Genus	serum_cytokines	0.528	0.906	no	no	no	no	no	no	DM-DS
GDCA+blood	IL-9	GDCA+blood-IL-1ra+IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.632	0.906	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	IL-9	P-hydroxyhippuric acid+urine+Eotaxin+IL-9	Indirect	urine_cometabolism	serum_cytokines	0.436	0.906	no	no	no	no	no	no	DM-DS
acetic acid C2+blood	IL-9	acetic acid C2+blood+d18:1-20:1-SM+blood-GUDCA+blood+UDCA+blood+Eotaxin+IL-9	Indirect	serum_scfa	serum_cytokines	0.000193	0.906	up	dn	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	IL-9	isovaleric acid iso-C5+blood+PUFA+blood+SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin+IL-9	Indirect	serum_scfa	serum_cytokines	0.117	0.906	no	no	no	no	no	no	DM-DS
Clostridium	IL-9	Clostridium-IL-9	Direct	Genus	serum_cytokines	0.925	0.906	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	IL-9	T-¦Á-MCA+stool-UDCA+stool+18:0/20:3-PI+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.48	0.906	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-9	12-ketoDCA+blood+IL-9	Direct	serum_bileacids	serum_cytokines	0.517	0.906	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-9	"Butyricicoccus+12,13-EPOME+blood+18:1/18:1-PE+blood-IL-9"	Indirect	Genus	serum_cytokines	0.852	0.906	no	no	no	no	no	no	DM-DS
Blautia	Leptin	Blautia+L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	1.36E-05	0.706	up	dn	dn	no	no	no	DM-DS
Parabacteroides	Leptin	Parabacteroides-L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	DM-DS
Dorea	Leptin	Dorea+L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-DS
Faecalibacterium	Leptin	Faecalibacterium+PDGF-bb-Leptin	Indirect	Genus	DM-associated hormones	0.0039	0.706	no	dn	dn	no	no	no	DM-DS
TUDCA+blood	Leptin	TUDCA+blood+L-Phenylalanine+urine-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.706	no	no	dn	no	no	no	DM-DS
Bacteroides	Leptin	Bacteroides-Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.000267	0.706	dn	dn	up	no	no	no	DM-DS
Bacteroides	Leptin	Bacteroides-cAMP signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.000267	0.706	dn	dn	up	no	no	no	DM-DS
Bacteroides	Leptin	Bacteroides-Long-term depression-Leptin	Indirect	Genus	DM-associated hormones	0.000267	0.706	dn	dn	up	no	no	no	DM-DS
Propionic acid+stool	Leptin	Propionic acid+stool-L-Tyrosine+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.706	dn	no	up	no	no	no	DM-DS
[Ruminococcus]	Leptin	[Ruminococcus]+18:0/18:1-PE+blood+Leptin	Indirect	Genus	DM-associated hormones	0.0679	0.706	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	Leptin	[Ruminococcus]+L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.0679	0.706	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	Leptin	[Ruminococcus]-20:4-LPC+blood-Leptin	Indirect	Genus	DM-associated hormones	0.0679	0.706	no	no	dn	no	no	no	DM-DS
GUDCA+blood	Leptin	GUDCA+blood+Leptin	Direct	serum_bileacids	DM-associated hormones	0.0766	0.706	no	no	dn	no	no	no	DM-DS
UDCA+blood	Leptin	UDCA+blood+L-Phenylalanine+urine-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.0939	0.706	no	no	dn	no	no	no	DM-DS
Acetic acid+stool	Leptin	Acetic acid+stool-18:0/18:0-PS+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.706	dn	no	no	no	no	no	DM-DS
Alistipes	Leptin	Alistipes+nutriCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.0114	0.706	no	up	no	no	no	no	DM-DS
Alistipes	Leptin	Alistipes-18:2/16:0-PC+blood-Leptin	Indirect	Genus	DM-associated hormones	0.0114	0.706	no	up	no	no	no	no	DM-DS
Alistipes	Leptin	Alistipes-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.0114	0.706	no	up	no	no	no	no	DM-DS
Alistipes	Leptin	Alistipes-Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.0114	0.706	no	up	no	no	no	no	DM-DS
Butyricimonas	Leptin	Butyricimonas-GPC+blood+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-DS
Butyricimonas	Leptin	Butyricimonas-20:4-LPA+blood+PUFA/MUFA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-DS
Butyricimonas	Leptin	Butyricimonas-UFA%+blood+Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-DS
Butyricimonas	Leptin	Butyricimonas-Serine+blood+Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-DS
Butyricimonas	Leptin	Butyricimonas+Cholinergic synapse+20:4n6+blood-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-DS
Butyricimonas	Leptin	Butyricimonas-L-Asparagine+blood+PUFA%+blood-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-DS
Butyricimonas	Leptin	Butyricimonas-Creatinine+blood+PUFA%+blood-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-DS
Butyricimonas	Leptin	Butyricimonas-MUFA%+blood+PUFA%+blood-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-DS
Butyricimonas	Leptin	Butyricimonas-20:4-LPA+blood+PUFA%+blood-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-DS
Butyricimonas	Leptin	Butyricimonas-GPC+blood+PUFA%+blood-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-DS
Butyricimonas	Leptin	Butyricimonas-L-Methionine+blood+PUFA%+blood-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-DS
Butyricimonas	Leptin	Butyricimonas+18:0+blood+18:0/18:0-PS+blood+Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-DS
Butyricimonas	Leptin	Butyricimonas+Cholinergic synapse-L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-DS
Butyricimonas	Leptin	Butyricimonas-L-Methionine+blood+L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-DS
Butyricimonas	Leptin	Butyricimonas-L-Isoleucine+blood+L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-DS
Butyricimonas	Leptin	Butyricimonas+18:0+blood-9-HODE+blood-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-DS
Butyricimonas	Leptin	Butyricimonas-iso-DCA+blood-IP-10+Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-DS
Collinsella	Leptin	Collinsella-DL-Indole-3-lactic acid+urine-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-DS
5-Hydroxytryptamine+urine	Leptin	5-Hydroxytryptamine+urine+L-Phenylalanine+urine-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.171	0.706	no	no	no	no	no	no	DM-DS
Sarcina	Leptin	Sarcina+IP-10+Leptin	Indirect	Genus	DM-associated hormones	0.0703	0.706	no	no	no	no	no	no	DM-DS
Methanosphaera	Leptin	Methanosphaera-Roseburia+IP-10+Leptin	Indirect	Genus	DM-associated hormones	0.0703	0.706	no	no	no	no	no	no	DM-DS
Methanosphaera	Leptin	Methanosphaera-Roseburia-AA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.0703	0.706	no	no	no	no	no	no	DM-DS
Methanosphaera	Leptin	Methanosphaera-Roseburia+GUDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.0703	0.706	no	no	no	no	no	no	DM-DS
Methanosphaera	Leptin	Methanosphaera-Roseburia+20:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.0703	0.706	no	no	no	no	no	no	DM-DS
Methanosphaera	Leptin	Methanosphaera-Roseburia+L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.0703	0.706	no	no	no	no	no	no	DM-DS
iso-DCA+stool	Leptin	iso-DCA+stool+Propionic acid+stool-L-Tyrosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.706	no	no	no	no	no	no	DM-DS
LCA+stool	Leptin	LCA+stool-UDCA+stool+L-Tyrosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.706	no	no	no	no	no	no	DM-DS
Akkermansia	Leptin	Akkermansia-Cholinergic synapse+20:4n6+blood-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	DM-DS
Akkermansia	Leptin	Akkermansia-Cholinergic synapse-L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	DM-DS
Akkermansia	Leptin	Akkermansia+Proteoglycans in cancer+Central carbon metabolism in cancer+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	DM-DS
Akkermansia	Leptin	Akkermansia+Proteoglycans in cancer-PUFA%+blood-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	DM-DS
Akkermansia	Leptin	Akkermansia-Longevity regulating pathway+Gap junction-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	DM-DS
Akkermansia	Leptin	Akkermansia+Proteoglycans in cancer-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	DM-DS
Bifidobacterium	Leptin	Bifidobacterium-16:0+blood-Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-DS
Bifidobacterium	Leptin	Bifidobacterium+L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-DS
3-Hydroxytyramine hydrochloride+urine	Leptin	3-Hydroxytyramine hydrochloride+urine+5-Hydroxytryptamine+urine+L-Phenylalanine+urine-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.288	0.706	no	no	no	no	no	no	DM-DS
3-Hydroxytyramine hydrochloride+urine	Leptin	3-Hydroxytyramine hydrochloride+urine-Hippuric acid+urine-IL-6-IP-10+Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.288	0.706	no	no	no	no	no	no	DM-DS
Phenylacetyl L-GlutaMine+urine	Leptin	Phenylacetyl L-GlutaMine+urine-Leptin	Direct	urine_cometabolism	DM-associated hormones	0.0909	0.706	up	no	no	no	no	no	DM-DS
Ruminococcus	Leptin	Ruminococcus+Leptin	Direct	Genus	DM-associated hormones	0.335	0.706	no	no	no	no	no	no	DM-DS
GCDCA+blood	Leptin	GCDCA+blood+GUDCA+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.706	no	no	no	no	no	no	DM-DS
GCDCA+blood	Leptin	GCDCA+blood-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.706	no	no	no	no	no	no	DM-DS
GCDCA+blood	Leptin	GCDCA+blood+L-Tyrosine+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.706	no	no	no	no	no	no	DM-DS
ACA+blood	Leptin	ACA+blood-decanoic acid C10+blood+L-Phenylalanine+blood+L-Tyrosine+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.706	no	no	no	no	no	no	DM-DS
ACA+blood	Leptin	ACA+blood-decanoic acid C10+blood+L-Isoleucine+blood+L-Tyrosine+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.706	no	no	no	no	no	no	DM-DS
ACA+blood	Leptin	ACA+blood+EPA+blood-n6/n3+blood+PUFA/MUFA+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.706	no	no	no	no	no	no	DM-DS
ACA+blood	Leptin	ACA+blood-decanoic acid C10+blood+n6/n3+blood+PUFA/MUFA+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.706	no	no	no	no	no	no	DM-DS
ACA+blood	Leptin	ACA+blood+EPA+blood-n6/n3+blood+PUFA%+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.706	no	no	no	no	no	no	DM-DS
ACA+blood	Leptin	ACA+blood-decanoic acid C10+blood+n6/n3+blood+PUFA%+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.706	no	no	no	no	no	no	DM-DS
DCA+stool	Leptin	DCA+stool-L-Tryptophan+stool+8-HETE+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-DS
DCA+stool	Leptin	DCA+stool+HDCA+stool-16:0/20:4-PI+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-DS
DCA+stool	Leptin	DCA+stool-GCA+stool+DPA+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-DS
DCA+stool	Leptin	DCA+stool-L-Tryptophan+stool+9-HODE+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-DS
DCA+stool	Leptin	DCA+stool-GCA+stool+L-Tyrosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-DS
2-hydroxyhippuric acid+urine	Leptin	2-hydroxyhippuric acid+urine-3-Hydroxy-L-kynurenine+urine+DL-Indole-3-lactic acid+urine-Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.215	0.706	no	no	no	no	no	no	DM-DS
Hippuric acid+urine	Leptin	Hippuric acid+urine-IL-6-IP-10+Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.361	0.706	no	no	no	no	no	no	DM-DS
Butyric acid+stool	Leptin	Butyric acid+stool+L-Histidine+blood+PUFA%+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.102	0.706	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	Leptin	Butyric acid+stool-16:0/20:5-PC+blood+18:0/18:0-PS+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.102	0.706	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	Leptin	Butyric acid+stool-16:0/20:5-PC+blood+20:4n6+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.102	0.706	dn	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	Leptin	4-hydroxybenzoic acid+stool+L-Tryptophan+stool+8-HETE+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.706	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	Leptin	4-hydroxybenzoic acid+stool+L-Tryptophan+stool+9-HODE+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.706	no	dn	no	no	no	no	DM-DS
Turicibacter	Leptin	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.269	0.706	no	no	no	no	no	no	DM-DS
Turicibacter	Leptin	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.269	0.706	no	no	no	no	no	no	DM-DS
Turicibacter	Leptin	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.269	0.706	no	no	no	no	no	no	DM-DS
GCA+blood	Leptin	GCA+blood-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.706	no	no	no	no	no	no	DM-DS
ACA+stool	Leptin	ACA+stool-Kynurenic acid+stool-nutriCA+stool+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.706	no	no	no	no	no	no	DM-DS
ACA+stool	Leptin	ACA+stool-L-Tryptophan+stool+8-HETE+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.706	no	no	no	no	no	no	DM-DS
ACA+stool	Leptin	ACA+stool-L-Phenylalanine+stool+8-HETE+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.706	no	no	no	no	no	no	DM-DS
ACA+stool	Leptin	ACA+stool-L-Tryptophan+stool+9-HODE+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.706	no	no	no	no	no	no	DM-DS
ACA+stool	Leptin	ACA+stool-L-Phenylalanine+stool+9-HODE+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.706	no	no	no	no	no	no	DM-DS
CDCA+blood	Leptin	CDCA+blood-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.706	no	no	no	no	no	no	DM-DS
CDCA+blood	Leptin	CDCA+blood+GUDCA+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.706	no	no	no	no	no	no	DM-DS
CDCA+blood	Leptin	CDCA+blood-PUFA%+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.706	no	no	no	no	no	no	DM-DS
capric acid C6+blood	Leptin	capric acid C6+blood-HCA+blood-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	serum_scfa	DM-associated hormones	0.433	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Tight junction+Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Autophagy - animal-Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Hippo signaling pathway+Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Focal adhesion+Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Transcriptional misregulation in cancer+PDGF-bb-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Glycolysis / Gluconeogenesis-PDGF-bb-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-20:3/18:0-PC+blood-PDGF-bb-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	"Prevotella+Growth hormone synthesis, secretion and action+PDGF-bb-Leptin"	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Amoebiasis+PDGF-bb-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Prolactin signaling pathway+PDGF-bb-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Phospholipase D signaling pathway+PDGF-bb-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+TDCA+blood-IP-10+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+GDCA+blood-IP-10+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+20:4/18:0-PE+blood-IP-10+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	"Prevotella+Growth hormone synthesis, secretion and action-18:0/18:1-PC+blood+Leptin"	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Hippo signaling pathway+18:0/18:1-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	"Prevotella+Growth hormone synthesis, secretion and action-18:0/18:0-PC+blood+Leptin"	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Hippo signaling pathway+18:0/18:0-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	"Prevotella+Growth hormone synthesis, secretion and action-L-Tyrosine+blood+Leptin"	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Proteasome+L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+18:3n6+blood-8-HETE+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Tight junction+18:0/18:1-PE+blood+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+FoxO signaling pathway-18:0/18:1-PE+blood+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+18:3n6+blood-9-HODE+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+18:0+blood-9-HODE+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+18:3n6+blood-PUFA%+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Glycolysis / Gluconeogenesis-cAMP signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Proteasome-cAMP signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+n6+blood+DL-Indole-3-lactic acid+urine-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Endocrine resistance+DL-Indole-3-lactic acid+urine-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Measles+DHA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Glycolysis / Gluconeogenesis-Gap junction-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Proteasome-Gap junction-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Endocrine resistance+Gap junction-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Phospholipase D signaling pathway+Gap junction-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Proteasome-Serotonergic synapse-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Endocrine resistance+Serotonergic synapse-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Phospholipase D signaling pathway+Serotonergic synapse-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Glycolysis / Gluconeogenesis+nutriCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	"Prevotella+Growth hormone synthesis, secretion and action-nutriCA+stool+Leptin"	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Proteasome+nutriCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Phospholipase D signaling pathway-nutriCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Glycolysis / Gluconeogenesis-Long-term depression-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Proteasome-Long-term depression-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Endocrine resistance+Long-term depression-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Phospholipase D signaling pathway+Long-term depression-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Nicotinate and nicotinamide metabolism-GUDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Prolactin signaling pathway-GUDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Phospholipase D signaling pathway-GUDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Nicotinate and nicotinamide metabolism-Biosynthesis of cofactors+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Nicotinate and nicotinamide metabolism-Porphyrin and chlorophyll metabolism+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+18:0+blood+18:0/18:0-PS+blood+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Acetic acid+stool-18:0/18:0-PS+blood+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Prolactin signaling pathway+DPA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Glycolysis / Gluconeogenesis-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+18:3n6+blood-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Amoebiasis+Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Phospholipase D signaling pathway+Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Glycolysis / Gluconeogenesis-Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Autophagy - animal+Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Hippo signaling pathway-Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Focal adhesion-Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Proteasome-Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Nicotinate and nicotinamide metabolism+Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Prolactin signaling pathway+Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+Phospholipase D signaling pathway+Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+GDCA+blood+PUFA/MUFA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella+GDCA+blood+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
Prevotella	Leptin	Prevotella-Proteasome-Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-DS
TCA+blood	Leptin	TCA+blood+TUDCA+blood+L-Phenylalanine+urine-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.339	0.706	no	no	no	no	no	no	DM-DS
iso-DCA+blood	Leptin	iso-DCA+blood-IP-10+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.706	no	no	no	no	no	no	DM-DS
HCA+stool	Leptin	HCA+stool-HDCA+stool-16:0/20:4-PI+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.706	no	no	no	no	no	no	DM-DS
Roseburia	Leptin	Roseburia+IP-10+Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	DM-DS
Roseburia	Leptin	Roseburia-AA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	DM-DS
Roseburia	Leptin	Roseburia+GUDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	DM-DS
Roseburia	Leptin	Roseburia+20:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	DM-DS
Roseburia	Leptin	Roseburia+L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	Leptin	12-ketoDCA+stool+GCA+blood-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.706	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	Leptin	12-ketoDCA+stool-GCA+stool+DPA+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.706	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	Leptin	12-ketoDCA+stool-GCA+stool+L-Tyrosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.706	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	Leptin	12-ketoDCA+stool+HDCA+stool-16:0/20:4-PI+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.706	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	Leptin	12-ketoDCA+stool-MUFA%+blood+PUFA%+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.706	no	no	no	no	no	no	DM-DS
GLCA+blood	Leptin	GLCA+blood+TDCA+blood-IP-10+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.706	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	Leptin	L-Tryptophan+stool+9-HODE+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.706	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	Leptin	L-Tryptophan+stool+8-HETE+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.706	no	no	no	no	no	no	DM-DS
CA+blood	Leptin	CA+blood+GUDCA+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.706	no	no	no	no	no	no	DM-DS
CA+blood	Leptin	CA+blood-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.706	no	no	no	no	no	no	DM-DS
GUDCA+stool	Leptin	GUDCA+stool+TUDCA+stool+9-HODE+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.706	no	dn	no	no	no	no	DM-DS
GUDCA+stool	Leptin	GUDCA+stool+12-HEPE+blood-L-Tyrosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.706	no	dn	no	no	no	no	DM-DS
L-Phenylalanine+stool	Leptin	L-Phenylalanine+stool+8-HETE+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.706	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	Leptin	L-Phenylalanine+stool+9-HODE+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.706	no	no	no	no	no	no	DM-DS
butyric acid C4+blood	Leptin	butyric acid C4+blood+L-Ornithine+blood+PDGF-bb-Leptin	Indirect	serum_scfa	DM-associated hormones	0.407	0.706	no	no	no	no	no	no	DM-DS
GCA+stool	Leptin	GCA+stool+L-Tyrosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.706	no	no	no	no	no	no	DM-DS
GCA+stool	Leptin	GCA+stool+DPA+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.706	no	no	no	no	no	no	DM-DS
Coprococcus	Leptin	Coprococcus+L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.612	0.706	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+urine	Leptin	Indole-3-Acetic acid+urine+Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.657	0.706	no	no	no	no	no	no	DM-DS
Oscillospira	Leptin	Oscillospira-Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.62	0.706	no	no	no	no	no	no	DM-DS
HCA+blood	Leptin	HCA+blood-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.544	0.706	no	no	no	no	no	no	DM-DS
iso-LCA+stool	Leptin	iso-LCA+stool-UDCA+stool+L-Tyrosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.706	no	no	no	no	no	no	DM-DS
iso-LCA+stool	Leptin	iso-LCA+stool-TCA+stool-20:4-LPC+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.706	no	no	no	no	no	no	DM-DS
iso-LCA+stool	Leptin	iso-LCA+stool-TCA+stool+18:0/18:1-PE+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.706	no	no	no	no	no	no	DM-DS
DCA+blood	Leptin	DCA+blood+nutriCA+blood-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.706	no	no	no	no	no	no	DM-DS
DCA+blood	Leptin	DCA+blood+L-Histidine+blood+PUFA%+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.706	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	Leptin	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool+9-HODE+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.706	no	no	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	Leptin	"3-(3,4-dihydroxyphenyl)propionic acid+urine+DL-Indole-3-lactic acid+urine-Leptin"	Indirect	urine_cometabolism	DM-associated hormones	0.0125	0.706	up	up	no	no	no	no	DM-DS
nutriCA+blood	Leptin	nutriCA+blood-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.726	0.706	no	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+urine	Leptin	4-hydroxybenzoic acid+urine+Homovanillic acid+urine-IP-10+Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.52	0.706	no	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+urine	Leptin	4-hydroxybenzoic acid+urine+Indole-3-Acetic acid+urine+Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.52	0.706	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	Leptin	Indole-3-Acetic acid+stool-nutriCA+stool+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.706	no	no	no	no	no	no	DM-DS
TCA+stool	Leptin	TCA+stool+18:0/18:1-PE+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.706	no	no	no	no	no	no	DM-DS
TCA+stool	Leptin	TCA+stool-20:4-LPC+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.706	no	no	no	no	no	no	DM-DS
HDCA+stool	Leptin	HDCA+stool-16:0/20:4-PI+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Chronic myeloid leukemia+PDGF-bb-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Prostate cancer+PDGF-bb-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Glycolysis / Gluconeogenesis-PDGF-bb-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Cytosolic DNA-sensing pathway+PDGF-bb-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Transcriptional misregulation in cancer+PDGF-bb-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-TNF signaling pathway+PDGF-bb-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Chronic myeloid leukemia-18:0/18:0-PS+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Prostate cancer-18:0/18:0-PS+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Cytosolic DNA-sensing pathway-18:0/18:0-PS+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-TNF signaling pathway-18:0/18:0-PS+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Prostate cancer+8-HETE+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-TNF signaling pathway+8-HETE+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Carbon metabolism+nutriCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Proteasome+nutriCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Glycolysis / Gluconeogenesis+nutriCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Regulation of actin cytoskeleton+nutriCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Carbon metabolism-Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Proteasome-Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Glycolysis / Gluconeogenesis-Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Autophagy - animal+Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Regulation of actin cytoskeleton-Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Cytosolic DNA-sensing pathway+Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-RIG-I-like receptor signaling pathway+Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Hippo signaling pathway-Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-ErbB signaling pathway+Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-TNF signaling pathway+Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-JAK-STAT signaling pathway+Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Focal adhesion-Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-NOD-like receptor signaling pathway+Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-NF-kappa B signaling pathway+Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Glycolysis / Gluconeogenesis-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-JAK-STAT signaling pathway+Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Non-small cell lung cancer+Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-NOD-like receptor signaling pathway-20:2/18:0-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+TCA+stool+18:0/18:1-PE+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Small cell lung cancer-18:0/18:1-PE+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Vascular smooth muscle contraction+18:0/18:1-PE+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Tight junction+18:0/18:1-PE+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-FoxO signaling pathway-18:0/18:1-PE+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-JAK-STAT signaling pathway-18:0/18:1-PE+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Non-small cell lung cancer-18:0/18:1-PE+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-NOD-like receptor signaling pathway-18:0/20:3-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Renin secretion-DPA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Circadian entrainment-DPA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Vascular smooth muscle contraction-DPA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-JAK-STAT signaling pathway+DPA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-NOD-like receptor signaling pathway+DPA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+L-Methionine+blood+PUFA%+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-NOD-like receptor signaling pathway+PUFA%+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Hippo signaling pathway+18:0/18:0-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Arrhythmogenic right ventricular cardiomyopathy+18:0/18:0-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Proteasome-cAMP signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Glycolysis / Gluconeogenesis-cAMP signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Carbon metabolism-Gap junction-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Proteasome-Gap junction-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Glycolysis / Gluconeogenesis-Gap junction-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Proteasome+L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-ErbB signaling pathway-L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+L-Methionine+blood+L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Proteasome-Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Chronic myeloid leukemia+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Prostate cancer+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Cytosolic DNA-sensing pathway+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+TCA+stool-20:4-LPC+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Proteasome-Serotonergic synapse-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Circadian entrainment+Serotonergic synapse-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Hepatitis B-GUDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-NOD-like receptor signaling pathway-GUDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Carbon metabolism-Long-term depression-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Proteasome-Long-term depression-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Glycolysis / Gluconeogenesis-Long-term depression-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-PD-L1 expression and PD-1 checkpoint pathway in cancer+PUFA/MUFA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Regulation of actin cytoskeleton-PUFA/MUFA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-TNF signaling pathway+PUFA/MUFA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-NOD-like receptor signaling pathway+PUFA/MUFA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Adherens junction+18:0/18:1-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Hippo signaling pathway+18:0/18:1-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Arrhythmogenic right ventricular cardiomyopathy+18:0/18:1-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Thyroid hormone signaling pathway+18:0/18:1-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-NOD-like receptor signaling pathway-18:0/18:1-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Adherens junction+Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Insulin resistance-Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Platelet activation+Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Progesterone-mediated oocyte maturation-Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Platinum drug resistance-Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-T cell receptor signaling pathway-Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Renin secretion+Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Autophagy - animal-Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Regulation of actin cytoskeleton+Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Rap1 signaling pathway+Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-Spliceosome-Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-RIG-I-like receptor signaling pathway-Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Circadian entrainment+Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Hippo signaling pathway+Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Vascular smooth muscle contraction+Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Tight junction+Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Thyroid hormone signaling pathway+Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Oxytocin signaling pathway+Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-TNF signaling pathway-Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-JAK-STAT signaling pathway-Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira+Focal adhesion+Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-NOD-like receptor signaling pathway-Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Lachnospira	Leptin	Lachnospira-NF-kappa B signaling pathway-Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-DS
Fusobacterium	Leptin	Fusobacterium-18:0/18:0-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.628	0.706	no	no	no	no	no	no	DM-DS
Fusobacterium	Leptin	Fusobacterium-18:0/18:1-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.628	0.706	no	no	no	no	no	no	DM-DS
Fusobacterium	Leptin	Fusobacterium-GUDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.628	0.706	no	no	no	no	no	no	DM-DS
GCDCA+stool	Leptin	GCDCA+stool+L-Tyrosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.706	no	dn	no	no	no	no	DM-DS
GCDCA+stool	Leptin	GCDCA+stool+20:3n6+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.706	no	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	Leptin	5-Hydroxytryptamine+stool-nutriCA+stool+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.706	dn	dn	no	no	no	no	DM-DS
Odoribacter	Leptin	Odoribacter-Serotonergic synapse-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	DM-DS
Odoribacter	Leptin	Odoribacter-Gap junction-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	DM-DS
Odoribacter	Leptin	Odoribacter+16:0/20:4-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	DM-DS
Odoribacter	Leptin	Odoribacter-Long-term depression-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	DM-DS
Actinomyces	Leptin	Actinomyces+Coprococcus+L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.621	0.706	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	Leptin	Isobutyric acid+stool-nutriCA+stool+Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	Leptin	2-hydroxyphenylacetic acid+urine-L-Phenylalanine+urine-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.763	0.706	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	Leptin	"2-hydroxyphenylacetic acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine+DL-Indole-3-lactic acid+urine-Leptin"	Indirect	urine_cometabolism	DM-associated hormones	0.763	0.706	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	Leptin	2-hydroxyphenylacetic acid+urine-3-Hydroxy-L-kynurenine+urine+DL-Indole-3-lactic acid+urine-Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.763	0.706	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	Leptin	2-hydroxyphenylacetic acid+urine+Homovanillic acid+urine-IP-10+Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.763	0.706	no	no	no	no	no	no	DM-DS
Kynurenic acid+stool	Leptin	Kynurenic acid+stool-nutriCA+stool+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.706	dn	dn	no	no	no	no	DM-DS
Caproic acid+stool	Leptin	Caproic acid+stool-TCA+stool+18:0/18:1-PE+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.882	0.706	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Leptin	Caproic acid+stool+Indole-3-Acetic acid+stool-nutriCA+stool+Leptin	Indirect	stool_scfa	DM-associated hormones	0.882	0.706	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Leptin	Caproic acid+stool-TCA+stool-20:4-LPC+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.882	0.706	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Leptin	Caproic acid+stool+Phenylacetic acid+stool-20:3n6+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.882	0.706	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Leptin	Caproic acid+stool-GCA+stool+DPA+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.882	0.706	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Leptin	Caproic acid+stool+Phenylacetic acid+stool-L-Tyrosine+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.882	0.706	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Leptin	Caproic acid+stool-GCA+stool+L-Tyrosine+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.882	0.706	no	no	no	no	no	no	DM-DS
Caproic acid+stool	Leptin	Caproic acid+stool+Phenylacetic acid+stool-GUDCA+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.882	0.706	no	no	no	no	no	no	DM-DS
Eggerthella	Leptin	Eggerthella+nutriCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.912	0.706	no	no	no	no	no	no	DM-DS
Anaerotruncus	Leptin	Anaerotruncus-Ruminococcus+Leptin	Indirect	Genus	DM-associated hormones	0.904	0.706	no	no	no	no	no	no	DM-DS
Anaerostipes	Leptin	Anaerostipes-Neutrophil extracellular trap formation+PUFA%+blood-Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-DS
Anaerostipes	Leptin	Anaerostipes+RNA degradation-PUFA%+blood-Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-DS
Anaerostipes	Leptin	Anaerostipes+PI3K-Akt signaling pathway+Central carbon metabolism in cancer+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-DS
Anaerostipes	Leptin	Anaerostipes-Oxytocin signaling pathway+Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-DS
Anaerostipes	Leptin	Anaerostipes+Spliceosome-Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-DS
Anaerostipes	Leptin	Anaerostipes-Rap1 signaling pathway+Salivary secretion-Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-DS
Anaerostipes	Leptin	Anaerostipes+PI3K-Akt signaling pathway-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-DS
Anaerostipes	Leptin	Anaerostipes+RNA degradation-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-DS
Anaerostipes	Leptin	Anaerostipes-GDCA+blood+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-DS
Anaerostipes	Leptin	Anaerostipes-Alcoholism-IP-10+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-DS
Anaerostipes	Leptin	Anaerostipes-TDCA+blood-IP-10+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-DS
Anaerostipes	Leptin	Anaerostipes-GDCA+blood-IP-10+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-DS
Anaerostipes	Leptin	Anaerostipes-IL-6-IP-10+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-DS
Anaerostipes	Leptin	Anaerostipes-GDCA+blood+PUFA/MUFA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-DS
Anaerostipes	Leptin	Anaerostipes-Neutrophil extracellular trap formation-GUDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-DS
Anaerostipes	Leptin	Anaerostipes+RNA degradation+GUDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-DS
Anaerostipes	Leptin	Anaerostipes+Propionic acid+stool-L-Tyrosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-DS
TUDCA+stool	Leptin	TUDCA+stool+9-HODE+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.706	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool+L-Phenylalanine+stool+9-HODE+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool+Phenylacetic acid+stool-20:3n6+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool+L-Phenylalanine+stool+8-HETE+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool+Phenylacetic acid+stool-L-Tyrosine+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool-UDCA+stool+L-Tyrosine+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool+Phenylacetic acid+stool-GUDCA+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-DS
Paraprevotella	Leptin	Paraprevotella+IP-10+Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	DM-DS
Homovanillic acid+urine	Leptin	Homovanillic acid+urine-IP-10+Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-DS
TDCA+blood	Leptin	TDCA+blood-IP-10+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.155	0.706	no	up	no	no	no	no	DM-DS
DL-Indole-3-lactic acid+urine	Leptin	DL-Indole-3-lactic acid+urine-Leptin	Direct	urine_cometabolism	DM-associated hormones	0.00552	0.706	up	up	no	no	no	no	DM-DS
Phenaceturic acid+urine	Leptin	Phenaceturic acid+urine+Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.737	0.706	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	Leptin	¦Ø-MCA+stool-L-Tyrosine+stool-nutriCA+stool+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.706	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	Leptin	¦Ø-MCA+stool-Isobutyric acid+stool-nutriCA+stool+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.706	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	Leptin	¦Ø-MCA+stool+CDCA+stool+nutriCA+stool+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.706	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	Leptin	¦Ø-MCA+stool+CDCA+stool+20:3n6+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.706	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	Leptin	¦Ø-MCA+stool-L-Phenylalanine+stool+8-HETE+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.706	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	Leptin	¦Ø-MCA+stool-L-Tryptophan+stool+8-HETE+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.706	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	Leptin	¦Ø-MCA+stool-L-Tyrosine+stool+9-HODE+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.706	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	Leptin	¦Ø-MCA+stool-L-Phenylalanine+stool+9-HODE+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.706	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	Leptin	¦Ø-MCA+stool-L-Tryptophan+stool+9-HODE+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.706	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	Leptin	¦Ø-MCA+stool+GDCA+stool+IP-10+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.706	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	Leptin	¦Ø-MCA+stool+CDCA+stool+IP-10+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.706	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	Leptin	¦Ø-MCA+stool+GDCA+stool+L-Tyrosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.706	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	Leptin	¦Ø-MCA+stool+CDCA+stool+L-Tyrosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.706	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	Leptin	Phenylacetic acid+stool-GUDCA+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.706	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	Leptin	Phenylacetic acid+stool-L-Tyrosine+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.706	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	Leptin	Phenylacetic acid+stool-20:3n6+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.706	no	no	no	no	no	no	DM-DS
Gemmiger	Leptin	Gemmiger+Central carbon metabolism in cancer+Leptin	Indirect	Genus	DM-associated hormones	0.595	0.706	no	no	no	no	no	no	DM-DS
GDCA+stool	Leptin	GDCA+stool+L-Tyrosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	DM-DS
GDCA+stool	Leptin	GDCA+stool+IP-10+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	DM-DS
Methanobrevibacter	Leptin	Methanobrevibacter-Cystine+blood+PUFA%+blood-Leptin	Indirect	Genus	DM-associated hormones	0.629	0.706	no	no	no	no	no	no	DM-DS
Methanobrevibacter	Leptin	Methanobrevibacter+d18:1-14:0-SM+blood-PUFA%+blood-Leptin	Indirect	Genus	DM-associated hormones	0.629	0.706	no	no	no	no	no	no	DM-DS
Methanobrevibacter	Leptin	Methanobrevibacter-Alcoholism-IP-10+Leptin	Indirect	Genus	DM-associated hormones	0.629	0.706	no	no	no	no	no	no	DM-DS
Methanobrevibacter	Leptin	Methanobrevibacter+d18:1-14:0-SM+blood-PDGF-bb-Leptin	Indirect	Genus	DM-associated hormones	0.629	0.706	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	Leptin	L-Tyrosine+stool+9-HODE+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.706	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	Leptin	L-Tyrosine+stool-nutriCA+stool+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.706	no	no	no	no	no	no	DM-DS
CDCA+stool	Leptin	CDCA+stool+nutriCA+stool+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.706	no	no	no	no	no	no	DM-DS
CDCA+stool	Leptin	CDCA+stool+L-Tyrosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.706	no	no	no	no	no	no	DM-DS
CDCA+stool	Leptin	CDCA+stool+IP-10+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.706	no	no	no	no	no	no	DM-DS
CDCA+stool	Leptin	CDCA+stool+20:3n6+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.706	no	no	no	no	no	no	DM-DS
CA+stool	Leptin	CA+stool+L-Tyrosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.706	no	no	no	no	no	no	DM-DS
CA+stool	Leptin	CA+stool+nutriCA+stool+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.706	no	no	no	no	no	no	DM-DS
HDCA+blood	Leptin	HDCA+blood+Hypotaurine+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.706	no	no	no	no	no	no	DM-DS
UDCA+stool	Leptin	UDCA+stool+L-Tyrosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.706	no	no	no	no	no	no	DM-DS
TDCA+stool	Leptin	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.706	no	no	no	no	no	no	DM-DS
TDCA+stool	Leptin	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PE+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.706	no	no	no	no	no	no	DM-DS
TDCA+stool	Leptin	TDCA+stool-HDCA+blood+Hypotaurine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.706	no	no	no	no	no	no	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	Leptin	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-PDGF-bb-Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.973	0.706	no	no	no	no	no	no	DM-DS
Desulfovibrio	Leptin	Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.27	0.706	no	no	no	no	no	no	DM-DS
Desulfovibrio	Leptin	Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.27	0.706	no	no	no	no	no	no	DM-DS
Desulfovibrio	Leptin	Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.27	0.706	no	no	no	no	no	no	DM-DS
nutriCA+stool	Leptin	nutriCA+stool+Leptin	Direct	stool_bileacids	DM-associated hormones	0.481	0.706	no	no	no	no	no	no	DM-DS
Bilophila	Leptin	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.528	0.706	no	no	no	no	no	no	DM-DS
Bilophila	Leptin	Bilophila+Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.528	0.706	no	no	no	no	no	no	DM-DS
Bilophila	Leptin	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.528	0.706	no	no	no	no	no	no	DM-DS
GDCA+blood	Leptin	GDCA+blood+Hypotaurine+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.706	no	no	no	no	no	no	DM-DS
GDCA+blood	Leptin	GDCA+blood-IP-10+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.706	no	no	no	no	no	no	DM-DS
GDCA+blood	Leptin	GDCA+blood+PUFA/MUFA+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.706	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	Leptin	P-hydroxyhippuric acid+urine+Eotaxin-IL-6-IP-10+Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.436	0.706	no	no	no	no	no	no	DM-DS
acetic acid C2+blood	Leptin	acetic acid C2+blood+d18:1-20:1-SM+blood-GUDCA+blood+Leptin	Indirect	serum_scfa	DM-associated hormones	0.000193	0.706	up	dn	no	no	no	no	DM-DS
acetic acid C2+blood	Leptin	acetic acid C2+blood+d18:1-20:1-SM+blood-L-Tyrosine+blood+Leptin	Indirect	serum_scfa	DM-associated hormones	0.000193	0.706	up	dn	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	Leptin	isovaleric acid iso-C5+blood-L-Phenylalanine+blood+L-Tyrosine+blood+Leptin	Indirect	serum_scfa	DM-associated hormones	0.117	0.706	no	no	no	no	no	no	DM-DS
L-Phenylalanine+urine	Leptin	L-Phenylalanine+urine-Phenylacetyl L-GlutaMine+urine-Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.0908	0.706	no	up	no	no	no	no	DM-DS
Clostridium	Leptin	Clostridium-18:2-LPC+blood-Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-DS
Clostridium	Leptin	Clostridium+18:0/18:0-PS+blood+Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-DS
Clostridium	Leptin	Clostridium-DL-Indole-3-lactic acid+urine-Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-DS
Clostridium	Leptin	Clostridium-Long-term depression-Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-DS
Clostridium	Leptin	Clostridium-9-HODE+blood-Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-DS
Clostridium	Leptin	Clostridium+nutriCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-DS
Clostridium	Leptin	Clostridium-Relaxin signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-DS
Clostridium	Leptin	Clostridium-PUFA/MUFA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-DS
Clostridium	Leptin	Clostridium-Gap junction-Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-DS
Clostridium	Leptin	Clostridium+20:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-DS
Clostridium	Leptin	Clostridium+18:0/20:3-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-DS
Clostridium	Leptin	Clostridium-cAMP signaling pathway-Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-DS
Clostridium	Leptin	Clostridium+18:0/18:1-PE+blood+Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-DS
Clostridium	Leptin	Clostridium-Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-DS
Clostridium	Leptin	Clostridium+20:2/18:0-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	Leptin	T-¦Á-MCA+stool-UDCA+stool+L-Tyrosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.706	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	Leptin	T-¦Á-MCA+stool+TUDCA+stool+9-HODE+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.706	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	Leptin	12-ketoDCA+blood-18:0/18:1-PE+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.706	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	Leptin	12-ketoDCA+blood-18:0/18:0-PS+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.706	no	no	no	no	no	no	DM-DS
Butyricicoccus	Leptin	Butyricicoccus-DL-Indole-3-lactic acid+urine-Leptin	Indirect	Genus	DM-associated hormones	0.852	0.706	no	no	no	no	no	no	DM-DS
3-Hydroxy-L-kynurenine+urine	Leptin	3-Hydroxy-L-kynurenine+urine+DL-Indole-3-lactic acid+urine-Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.401	0.706	no	no	no	no	no	no	DM-DS
Blautia	IP-10	Blautia-TDCA+blood-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	DM-DS
Blautia	IP-10	Blautia+GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	DM-DS
Blautia	IP-10	Blautia+CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	DM-DS
Blautia	IP-10	Blautia+L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	DM-DS
Parabacteroides	IP-10	Parabacteroides-L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	4.19E-05	0.394	no	up	up	no	no	no	DM-DS
Parabacteroides	IP-10	Parabacteroides+d18:1-22:0-SM+blood+IP-10	Indirect	Genus	serum_cytokines	4.19E-05	0.394	no	up	up	no	no	no	DM-DS
Dorea	IP-10	Dorea+L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	DM-DS
Dorea	IP-10	Dorea+GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	DM-DS
Dorea	IP-10	Dorea+CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	DM-DS
Faecalibacterium	IP-10	Faecalibacterium-Phenylacetic acid+stool-L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	IP-10	Faecalibacterium+GCDCA+stool+L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	IP-10	Faecalibacterium-Phenylacetic acid+stool-16:0/16:1-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	IP-10	Faecalibacterium+GCDCA+stool+16:0/16:1-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	IP-10	Faecalibacterium-Phenylacetic acid+stool-16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	IP-10	Faecalibacterium+GCDCA+stool+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	IP-10	Faecalibacterium+GCDCA+stool+GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	IP-10	Faecalibacterium-d18:1-16:1-SM+blood+d18:1-22:0-SM+blood+IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	IP-10	Faecalibacterium-d18:1-14:0-SM+blood+d18:1-22:0-SM+blood+IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	IP-10	Faecalibacterium-Phenylacetic acid+stool-20:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	IP-10	Faecalibacterium+GCDCA+stool+20:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-DS
TUDCA+blood	IP-10	TUDCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.0282	0.394	no	no	dn	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides+18:0/22:6-PC+blood-TDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides+20:3/18:0-PC+blood-TDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	"Bacteroides-Growth hormone synthesis, secretion and action+TDCA+blood-IP-10"	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides+Longevity regulating pathway - multiple species-TDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides+Parabacteroides-L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	"Bacteroides-Growth hormone synthesis, secretion and action-L-Tyrosine+blood+IP-10"	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides+18:0/20:4-PC+blood-L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	"Bacteroides-Growth hormone synthesis, secretion and action-CDCA+stool+IP-10"	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides-Pathways in cancer-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides+Leishmaniasis+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides-Relaxin signaling pathway+GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides-cAMP signaling pathway+GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides+18:0/22:6-PC+blood-GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	"Bacteroides-Growth hormone synthesis, secretion and action+GDCA+blood-IP-10"	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides+Longevity regulating pathway - multiple species-GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides-Long-term depression+GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides+16:0/22:6-PC+blood-20:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides+18:0/20:4-PC+blood-20:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	"Bacteroides-Growth hormone synthesis, secretion and action-18:0/18:1-PC+blood+IP-10"	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	"Bacteroides-Growth hormone synthesis, secretion and action-18:0/18:0-PC+blood+IP-10"	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	"Bacteroides-Growth hormone synthesis, secretion and action-GDCA+stool+IP-10"	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides+Glycolysis / Gluconeogenesis+GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides-Long-term depression+Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides+4-hydroxybenzoic acid+urine+Homovanillic acid+urine-IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides+18:0/22:6-PE+blood+20:4/18:0-PE+blood-IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides-14:0+blood-d18:0-24:1-SM+blood+IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides+Legionellosis+d18:0-24:1-SM+blood+IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides-14:0+blood-d18:1-22:0-SM+blood+IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides+d18:1-20:0-SM+blood+d18:1-22:0-SM+blood+IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Bacteroides	IP-10	Bacteroides+Parabacteroides+d18:1-22:0-SM+blood+IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-DS
Propionic acid+stool	IP-10	Propionic acid+stool-L-Tyrosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-DS
[Ruminococcus]	IP-10	[Ruminococcus]+L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.0679	0.394	no	no	dn	no	no	no	DM-DS
GUDCA+blood	IP-10	GUDCA+blood+TUDCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.0766	0.394	no	no	dn	no	no	no	DM-DS
GUDCA+blood	IP-10	GUDCA+blood+HCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.0766	0.394	no	no	dn	no	no	no	DM-DS
GUDCA+blood	IP-10	GUDCA+blood+UDCA+blood+Eotaxin-IL-6-IP-10	Indirect	serum_bileacids	serum_cytokines	0.0766	0.394	no	no	dn	no	no	no	DM-DS
UDCA+blood	IP-10	UDCA+blood+Eotaxin-IL-6-IP-10	Indirect	serum_bileacids	serum_cytokines	0.0939	0.394	no	no	dn	no	no	no	DM-DS
Acetic acid+stool	IP-10	Acetic acid+stool-16:0/18:0-PS+blood+20:4/18:0-PE+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0656	0.394	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	IP-10	Acetic acid+stool-18:0/18:0-PS+blood+20:4/18:0-PE+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0656	0.394	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	IP-10	Acetic acid+stool-16:0/18:0-PS+blood-GDCA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0656	0.394	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	IP-10	Acetic acid+stool-18:0/18:0-PS+blood-GDCA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0656	0.394	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	IP-10	Acetic acid+stool-18:0/18:0-PS+blood+18:0/18:1-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.0656	0.394	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	IP-10	Acetic acid+stool-14:0+blood-d18:0-24:1-SM+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.0656	0.394	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	IP-10	Acetic acid+stool-14:0+blood-d18:1-22:0-SM+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.0656	0.394	dn	no	no	no	no	no	DM-DS
Alistipes	IP-10	Alistipes-Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.0114	0.394	no	up	no	no	no	no	DM-DS
Alistipes	IP-10	Alistipes-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.0114	0.394	no	up	no	no	no	no	DM-DS
Butyricimonas	IP-10	Butyricimonas-iso-DCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-DS
Collinsella	IP-10	Collinsella+Roseburia+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-DS
5-Hydroxytryptamine+urine	IP-10	5-Hydroxytryptamine+urine-Hippuric acid+urine-IL-6-IP-10	Indirect	urine_cometabolism	serum_cytokines	0.171	0.394	no	no	no	no	no	no	DM-DS
Sarcina	IP-10	Sarcina+IP-10	Direct	Genus	serum_cytokines	0.0703	0.394	no	no	no	no	no	no	DM-DS
Methanosphaera	IP-10	Methanosphaera-Roseburia+IP-10	Indirect	Genus	serum_cytokines	0.0703	0.394	no	no	no	no	no	no	DM-DS
iso-DCA+stool	IP-10	iso-DCA+stool+Propionic acid+stool-L-Tyrosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.155	0.394	no	no	no	no	no	no	DM-DS
LCA+stool	IP-10	LCA+stool-UDCA+stool-TDCA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-DS
LCA+stool	IP-10	LCA+stool-UDCA+stool-GDCA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-DS
LCA+stool	IP-10	LCA+stool-UDCA+stool+L-Tyrosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-DS
LCA+stool	IP-10	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-DS
Akkermansia	IP-10	Akkermansia-Cholinergic synapse+20:4/18:0-PE+blood-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-DS
Akkermansia	IP-10	Akkermansia-Cholinergic synapse-L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-DS
Akkermansia	IP-10	Akkermansia-Longevity regulating pathway-CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-DS
Akkermansia	IP-10	Akkermansia-Longevity regulating pathway+GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-DS
Akkermansia	IP-10	Akkermansia-Longevity regulating pathway-GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-DS
Bifidobacterium	IP-10	Bifidobacterium+L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.105	0.394	no	dn	no	no	no	no	DM-DS
3-Hydroxytyramine hydrochloride+urine	IP-10	3-Hydroxytyramine hydrochloride+urine-Hippuric acid+urine-IL-6-IP-10	Indirect	urine_cometabolism	serum_cytokines	0.288	0.394	no	no	no	no	no	no	DM-DS
Ruminococcus	IP-10	Ruminococcus+IP-10	Direct	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-DS
GCDCA+blood	IP-10	GCDCA+blood+L-Tyrosine+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.31	0.394	no	no	no	no	no	no	DM-DS
ACA+blood	IP-10	ACA+blood-decanoic acid C10+blood+L-Phenylalanine+blood+L-Tyrosine+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.338	0.394	no	no	no	no	no	no	DM-DS
ACA+blood	IP-10	ACA+blood-decanoic acid C10+blood+L-Isoleucine+blood+L-Tyrosine+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.338	0.394	no	no	no	no	no	no	DM-DS
ACA+blood	IP-10	ACA+blood+EPA+blood+TXB2+blood+Homovanillic acid+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.338	0.394	no	no	no	no	no	no	DM-DS
ACA+blood	IP-10	ACA+blood-decanoic acid C10+blood-TXB2+blood+Homovanillic acid+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.338	0.394	no	no	no	no	no	no	DM-DS
DCA+stool	IP-10	DCA+stool-L-Tryptophan+stool+Homovanillic acid+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-DS
DCA+stool	IP-10	DCA+stool-GCA+stool+GDCA+stool+IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-DS
DCA+stool	IP-10	DCA+stool-GCA+stool-GDCA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-DS
DCA+stool	IP-10	DCA+stool-GCA+stool+L-Tyrosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-DS
Hippuric acid+urine	IP-10	Hippuric acid+urine-IL-6-IP-10	Indirect	urine_cometabolism	serum_cytokines	0.361	0.394	no	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood-Creatinine+blood+iso-DCA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood-18:1/20:3-PC+blood-Homovanillic acid+urine-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood-L-Methionine+blood+L-Tyrosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool+L-Histidine+blood+L-Methionine+blood+L-Tyrosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood-L-Isoleucine+blood+L-Tyrosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool+L-Histidine+blood+L-Isoleucine+blood+L-Tyrosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood-L-Lysine+blood+L-Tyrosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool+L-Histidine+blood+L-Lysine+blood+L-Tyrosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood-L-Phenylalanine+blood+L-Tyrosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+20:4n6+blood-L-Tyrosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+18:0/20:5-PC+blood-L-Tyrosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+18:0/20:4-PC+blood-L-Tyrosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+d18:1-14:0-SM+blood+d18:1-22:0-SM+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+18:0/22:6-PE+blood+20:4/18:0-PE+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+18:0/18:0-PS+blood+20:4/18:0-PE+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+18:0/22:6-PC+blood-TDCA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+18:0/22:6-PA+blood-TDCA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+18:0/22:6-PC+blood-GDCA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+18:0/22:6-PA+blood-GDCA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+18:0/18:0-PS+blood-GDCA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-6-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool+L-Citrulline+blood+Eotaxin-IL-6-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood-20:3-LPC+blood+20:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood-18:1/20:3-PC+blood+20:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood-20:3-LPE+blood+20:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+16:0/22:6-PC+blood-20:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+18:0/20:5-PC+blood-20:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+18:0/20:4-PC+blood-20:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+20:5-LPC+blood+AA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+18:0/20:5-PC+blood+AA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+22:6-LPC+blood+AA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+18:0/18:0-PS+blood+18:0/18:1-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood-18:1/20:3-PC+blood+20:2/18:0-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IP-10	Butyric acid+stool-16:0/20:5-PC+blood+18:0/20:5-PC+blood-20:2/18:0-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	IP-10	4-hydroxybenzoic acid+stool+L-Tryptophan+stool+Homovanillic acid+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.394	no	dn	no	no	no	no	DM-DS
Turicibacter	IP-10	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.269	0.394	no	no	no	no	no	no	DM-DS
Turicibacter	IP-10	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.269	0.394	no	no	no	no	no	no	DM-DS
Turicibacter	IP-10	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.269	0.394	no	no	no	no	no	no	DM-DS
Turicibacter	IP-10	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.269	0.394	no	no	no	no	no	no	DM-DS
Turicibacter	IP-10	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.269	0.394	no	no	no	no	no	no	DM-DS
Turicibacter	IP-10	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.269	0.394	no	no	no	no	no	no	DM-DS
Turicibacter	IP-10	Turicibacter+Desulfovibrio+Antigen processing and presentation+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.269	0.394	no	no	no	no	no	no	DM-DS
Turicibacter	IP-10	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.269	0.394	no	no	no	no	no	no	DM-DS
Turicibacter	IP-10	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.269	0.394	no	no	no	no	no	no	DM-DS
Turicibacter	IP-10	Turicibacter+Desulfovibrio+Antigen processing and presentation+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.269	0.394	no	no	no	no	no	no	DM-DS
GCA+blood	IP-10	GCA+blood+TDCA+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.16	0.394	no	no	no	no	no	no	DM-DS
ACA+stool	IP-10	ACA+stool-L-Phenylalanine+stool-16:0/20:3-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.417	0.394	no	no	no	no	no	no	DM-DS
ACA+stool	IP-10	ACA+stool-L-Tryptophan+stool+Homovanillic acid+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.417	0.394	no	no	no	no	no	no	DM-DS
ACA+stool	IP-10	ACA+stool-L-Phenylalanine+stool+Homovanillic acid+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.417	0.394	no	no	no	no	no	no	DM-DS
CDCA+blood	IP-10	CDCA+blood+GCDCA+blood+L-Tyrosine+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.506	0.394	no	no	no	no	no	no	DM-DS
capric acid C6+blood	IP-10	capric acid C6+blood-HCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10	Indirect	serum_scfa	serum_cytokines	0.433	0.394	no	no	no	no	no	no	DM-DS
Prevotella	IP-10	Prevotella+TDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.287	0.394	no	no	no	no	no	no	DM-DS
Prevotella	IP-10	Prevotella+GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.287	0.394	no	no	no	no	no	no	DM-DS
Prevotella	IP-10	Prevotella+20:4/18:0-PE+blood-IP-10	Indirect	Genus	serum_cytokines	0.287	0.394	no	no	no	no	no	no	DM-DS
TCA+blood	IP-10	TCA+blood+TUDCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.339	0.394	no	no	no	no	no	no	DM-DS
iso-DCA+blood	IP-10	iso-DCA+blood-IP-10	Direct	serum_bileacids	serum_cytokines	0.38	0.394	no	no	no	no	no	no	DM-DS
HCA+stool	IP-10	HCA+stool-HDCA+stool-16:0/20:4-PI+blood-AA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.155	0.394	no	no	no	no	no	no	DM-DS
HCA+stool	IP-10	HCA+stool-HDCA+stool-16:0/20:4-PI+blood-iso-DCA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.155	0.394	no	no	no	no	no	no	DM-DS
HCA+stool	IP-10	HCA+stool-HDCA+stool-16:0/20:4-PI+blood+18:0/20:3-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.155	0.394	no	no	no	no	no	no	DM-DS
HCA+stool	IP-10	HCA+stool-HDCA+stool+Eotaxin-IL-6-IP-10	Indirect	stool_bileacids	serum_cytokines	0.155	0.394	no	no	no	no	no	no	DM-DS
HCA+stool	IP-10	HCA+stool-HDCA+stool+Hippuric acid+urine-IL-6-IP-10	Indirect	stool_bileacids	serum_cytokines	0.155	0.394	no	no	no	no	no	no	DM-DS
HCA+stool	IP-10	HCA+stool-HDCA+stool-16:0/20:4-PI+blood+20:2/18:0-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.155	0.394	no	no	no	no	no	no	DM-DS
Roseburia	IP-10	Roseburia+IP-10	Direct	Genus	serum_cytokines	0.495	0.394	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	IP-10	12-ketoDCA+stool-GCA+stool+GDCA+stool+IP-10	Indirect	stool_bileacids	serum_cytokines	0.505	0.394	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	IP-10	12-ketoDCA+stool-GCA+stool-GDCA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.505	0.394	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	IP-10	12-ketoDCA+stool-GCA+stool+L-Tyrosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.505	0.394	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	IP-10	12-ketoDCA+stool+Hippuric acid+urine-IL-6-IP-10	Indirect	stool_bileacids	serum_cytokines	0.505	0.394	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	IP-10	12-ketoDCA+stool+GCA+blood+TDCA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.505	0.394	no	no	no	no	no	no	DM-DS
GLCA+blood	IP-10	GLCA+blood+TDCA+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.319	0.394	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IP-10	L-Tryptophan+stool+Homovanillic acid+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.557	0.394	no	no	no	no	no	no	DM-DS
CA+blood	IP-10	CA+blood+TDCA+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.606	0.394	no	no	no	no	no	no	DM-DS
GUDCA+stool	IP-10	GUDCA+stool+12-HEPE+blood-L-Tyrosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.0085	0.394	no	dn	no	no	no	no	DM-DS
L-Phenylalanine+stool	IP-10	L-Phenylalanine+stool-16:0/20:3-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.398	0.394	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	IP-10	L-Phenylalanine+stool+Homovanillic acid+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.398	0.394	no	no	no	no	no	no	DM-DS
GCA+stool	IP-10	GCA+stool-GDCA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0809	0.394	no	no	no	no	no	no	DM-DS
GCA+stool	IP-10	GCA+stool+L-Tyrosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.0809	0.394	no	no	no	no	no	no	DM-DS
GCA+stool	IP-10	GCA+stool+GDCA+stool+IP-10	Indirect	stool_bileacids	serum_cytokines	0.0809	0.394	no	no	no	no	no	no	DM-DS
Coprococcus	IP-10	Coprococcus+L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.612	0.394	no	no	no	no	no	no	DM-DS
Coprococcus	IP-10	Coprococcus+Roseburia+IP-10	Indirect	Genus	serum_cytokines	0.612	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	"Oscillospira-Parathyroid hormone synthesis, secretion and action+TDCA+blood-IP-10"	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira+JAK-STAT signaling pathway-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira-Vibrio cholerae infection+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira+Platinum drug resistance-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira+Progesterone-mediated oocyte maturation-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira-Rap1 signaling pathway+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira+Spliceosome-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira+T cell receptor signaling pathway-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira+MAPK signaling pathway-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira-Platelet activation+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira+FoxO signaling pathway-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira-Focal adhesion+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira-Human cytomegalovirus infection+20:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira+MAPK signaling pathway-20:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira-Human cytomegalovirus infection+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira+MAPK signaling pathway-16:0/16:1-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira-Salivary secretion+20:4/18:0-PE+blood-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira+T cell receptor signaling pathway-20:4/18:0-PE+blood-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira+Platinum drug resistance-Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira+Progesterone-mediated oocyte maturation-Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira-Rap1 signaling pathway+Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira+Spliceosome-Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira-Salivary secretion+Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira+T cell receptor signaling pathway-Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira+MAPK signaling pathway-Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira-Retrograde endocannabinoid signaling-AA+blood-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
Oscillospira	IP-10	Oscillospira+MAPK signaling pathway+AA+blood-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-DS
HCA+blood	IP-10	HCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.544	0.394	no	no	no	no	no	no	DM-DS
iso-LCA+stool	IP-10	iso-LCA+stool-UDCA+stool-GDCA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.72	0.394	no	no	no	no	no	no	DM-DS
iso-LCA+stool	IP-10	iso-LCA+stool-UDCA+stool-TDCA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.72	0.394	no	no	no	no	no	no	DM-DS
iso-LCA+stool	IP-10	iso-LCA+stool-UDCA+stool+L-Tyrosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.72	0.394	no	no	no	no	no	no	DM-DS
iso-LCA+stool	IP-10	iso-LCA+stool-UDCA+stool+16:0/20:3-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.72	0.394	no	no	no	no	no	no	DM-DS
DCA+blood	IP-10	DCA+blood+L-Histidine+blood+L-Lysine+blood+L-Tyrosine+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.122	0.394	no	no	no	no	no	no	DM-DS
DCA+blood	IP-10	DCA+blood+L-Histidine+blood+L-Isoleucine+blood+L-Tyrosine+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.122	0.394	no	no	no	no	no	no	DM-DS
DCA+blood	IP-10	DCA+blood+L-Histidine+blood+L-Methionine+blood+L-Tyrosine+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.122	0.394	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IP-10	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool+9-HODE+blood+AA+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.33	0.394	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IP-10	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Tyrosine+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.33	0.394	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IP-10	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-d18:1-14:0-SM+blood+d18:1-22:0-SM+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.33	0.394	no	no	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IP-10	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-6-IP-10"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.394	up	up	no	no	no	no	DM-DS
nutriCA+blood	IP-10	nutriCA+blood+UDCA+blood+Eotaxin-IL-6-IP-10	Indirect	serum_bileacids	serum_cytokines	0.726	0.394	no	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+urine	IP-10	4-hydroxybenzoic acid+urine+Homovanillic acid+urine-IP-10	Indirect	urine_cometabolism	serum_cytokines	0.52	0.394	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool-UDCA+stool-TDCA+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool-nutriCA+stool+18:0/18:0-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-20:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool-nutriCA+stool+20:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool-nutriCA+stool+18:0/18:1-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool-nutriCA+stool+18:0/20:3-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool-nutriCA+stool+18:0/20:2-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool-nutriCA+stool+20:2/18:0-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-16:0/20:3-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool-nutriCA+stool+16:0/20:3-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool-UDCA+stool+16:0/20:3-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool-nutriCA+stool-AA+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool-UDCA+stool-GDCA+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-L-Tyrosine+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool-UDCA+stool+L-Tyrosine+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-16:0/16:1-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool+18:1/18:1-PE+blood+20:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool-18:1/20:4-PC+blood-20:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool+16:0/18:2-PI+blood+20:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool+18:1/18:1-PC+blood+20:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool+18:0/20:3-PI+blood+20:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool-16:0/22:6-PC+blood-20:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool-18:0/20:5-PC+blood-20:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool-18:0/20:4-PC+blood-20:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool+16:0/18:2-PI+blood+18:0/20:3-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool+18:1/18:1-PE+blood+20:4/18:0-PE+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool+18:1/18:1-PE+blood-AA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool+16:0/18:2-PI+blood-AA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool-18:0/20:5-PC+blood+AA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool-20:4-LPC+blood+AA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool+16:0/18:2-PI+blood+20:2/18:0-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool+18:1/18:1-PC+blood+20:2/18:0-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool+18:0/20:3-PI+blood+20:2/18:0-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool-18:0/20:5-PC+blood-20:2/18:0-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool-d18:1-20:1-SM+blood-L-Tyrosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool+L-Proline+blood+L-Tyrosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool-18:0/20:5-PC+blood-L-Tyrosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool-18:0/20:4-PC+blood-L-Tyrosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool-20:4-LPC+blood-L-Tyrosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool-TXB2+blood+Homovanillic acid+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool+18:1/18:1-PC+blood-Homovanillic acid+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool-d18:1-20:1-SM+blood+Homovanillic acid+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool-20:0/20:5-PC+blood+d18:1-22:0-SM+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
TCA+stool	IP-10	TCA+stool-d18:1-20:0-SM+blood+d18:1-22:0-SM+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-DS
HDCA+stool	IP-10	HDCA+stool-16:0/20:4-PI+blood-AA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.176	0.394	no	no	no	no	no	no	DM-DS
HDCA+stool	IP-10	HDCA+stool-16:0/20:4-PI+blood-iso-DCA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.176	0.394	no	no	no	no	no	no	DM-DS
HDCA+stool	IP-10	HDCA+stool-16:0/20:4-PI+blood+18:0/20:3-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.176	0.394	no	no	no	no	no	no	DM-DS
HDCA+stool	IP-10	HDCA+stool+Eotaxin-IL-6-IP-10	Indirect	stool_bileacids	serum_cytokines	0.176	0.394	no	no	no	no	no	no	DM-DS
HDCA+stool	IP-10	HDCA+stool+Hippuric acid+urine-IL-6-IP-10	Indirect	stool_bileacids	serum_cytokines	0.176	0.394	no	no	no	no	no	no	DM-DS
HDCA+stool	IP-10	HDCA+stool-16:0/20:4-PI+blood+20:2/18:0-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.176	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Vibrio cholerae infection+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Carbon metabolism+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Adherens junction+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-p53 signaling pathway-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Platelet activation+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Bacterial invasion of epithelial cells+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-Progesterone-mediated oocyte maturation-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-Platinum drug resistance-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-T cell receptor signaling pathway-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Regulation of actin cytoskeleton+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Rap1 signaling pathway+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-Spliceosome-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-Hippuric acid+urine-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-Signaling pathways regulating pluripotency of stem cells-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Tight junction+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Leukocyte transendothelial migration+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-FoxO signaling pathway-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-ErbB signaling pathway-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Oxytocin signaling pathway+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-JAK-STAT signaling pathway-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-Non-small cell lung cancer-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Focal adhesion+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Fluid shear stress and atherosclerosis+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-NOD-like receptor signaling pathway-20:2/18:0-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-Progesterone-mediated oocyte maturation-Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-Platinum drug resistance-Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-T cell receptor signaling pathway-Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Rap1 signaling pathway+Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-Spliceosome-Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-Signaling pathways regulating pluripotency of stem cells-Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Oxytocin signaling pathway+Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Carbon metabolism+CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Proteasome+CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Hippo signaling pathway+CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-NOD-like receptor signaling pathway-18:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-T cell receptor signaling pathway-20:4/18:0-PE+blood-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-Cytosolic DNA-sensing pathway-20:4/18:0-PE+blood-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Hippo signaling pathway+18:0/18:0-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Arrhythmogenic right ventricular cardiomyopathy+18:0/18:0-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Carbon metabolism+GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Proteasome+GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Glycolysis / Gluconeogenesis+GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Proteasome-GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Regulation of actin cytoskeleton-GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Hippo signaling pathway-GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Proteasome+L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-ErbB signaling pathway-L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+L-Methionine+blood+L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Carbon metabolism+Homovanillic acid+urine-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-p53 signaling pathway-Homovanillic acid+urine-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Adherens junction+18:0/18:1-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Hippo signaling pathway+18:0/18:1-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Arrhythmogenic right ventricular cardiomyopathy+18:0/18:1-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira+Thyroid hormone signaling pathway+18:0/18:1-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Lachnospira	IP-10	Lachnospira-NOD-like receptor signaling pathway-18:0/18:1-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-DS
Fusobacterium	IP-10	Fusobacterium-18:0/18:0-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.628	0.394	no	no	no	no	no	no	DM-DS
Fusobacterium	IP-10	Fusobacterium-16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.628	0.394	no	no	no	no	no	no	DM-DS
Fusobacterium	IP-10	Fusobacterium-18:0/18:1-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.628	0.394	no	no	no	no	no	no	DM-DS
GCDCA+stool	IP-10	GCDCA+stool+L-Tyrosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IP-10	GCDCA+stool+20:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IP-10	GCDCA+stool+16:0/16:1-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IP-10	GCDCA+stool+16:0/20:3-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-DS
GCDCA+stool	IP-10	GCDCA+stool+GDCA+stool+IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:1-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool-UDCA+stool-GDCA+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:2-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool-nutriCA+stool+20:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool-UDCA+stool+16:0/20:3-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool-nutriCA+stool+16:0/20:3-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool-UDCA+stool+L-Tyrosine+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool-nutriCA+stool+20:2/18:0-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool-UDCA+stool-TDCA+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool-nutriCA+stool-AA+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:0-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Salmonella infection-TDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-GnRH signaling pathway+TDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	"Odoribacter-Growth hormone synthesis, secretion and action+TDCA+blood-IP-10"	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Endocrine resistance+TDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Chemical carcinogenesis - receptor activation+TDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Longevity regulating pathway - multiple species-TDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Pathogenic Escherichia coli infection+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Antigen processing and presentation+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Leishmaniasis+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Chemical carcinogenesis - receptor activation-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Carbon metabolism+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	"Odoribacter-Growth hormone synthesis, secretion and action-18:0/18:1-PC+blood+IP-10"	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	"Odoribacter-Growth hormone synthesis, secretion and action-18:0/18:0-PC+blood+IP-10"	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Proteasome-GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+GCA+stool-GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-GnRH signaling pathway+GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	"Odoribacter-Growth hormone synthesis, secretion and action+GDCA+blood-IP-10"	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Endocrine resistance+GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Long-term depression+GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Longevity regulating pathway - multiple species-GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+16:0/20:4-PI+blood+18:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+CA+stool+CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Serotonergic synapse-CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Salmonella infection+CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Proteasome+CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Cocaine addiction-CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Regulation of lipolysis in adipocytes-CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Glutamatergic synapse-CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Insulin secretion-CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-GnRH signaling pathway-CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Cortisol synthesis and secretion-CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	"Odoribacter-Growth hormone synthesis, secretion and action-CDCA+stool+IP-10"	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Endocrine resistance-CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Chemical carcinogenesis - receptor activation-CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Carbon metabolism+CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+16:0/20:4-PI+blood+20:2/18:0-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+CA+stool+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Antigen processing and presentation+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Chemical carcinogenesis - receptor activation-16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+CA+stool+L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Serotonergic synapse-L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Proteasome+L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+GCA+stool+L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	"Odoribacter-Growth hormone synthesis, secretion and action-L-Tyrosine+blood+IP-10"	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Gap junction-L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Chemical carcinogenesis - receptor activation-L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+16:0/20:4-PI+blood-iso-DCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+CA+stool+GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Serotonergic synapse-GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Proteasome+GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Glycolysis / Gluconeogenesis+GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Glutamatergic synapse-GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+GCA+stool+GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Cortisol synthesis and secretion-GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	"Odoribacter-Growth hormone synthesis, secretion and action-GDCA+stool+IP-10"	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Gap junction-GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Chemical carcinogenesis - receptor activation-GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Carbon metabolism+GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+16:0/20:4-PI+blood-AA+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Legionellosis+d18:0-24:1-SM+blood+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Carbon metabolism+Homovanillic acid+urine-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter+Fc gamma R-mediated phagocytosis+Homovanillic acid+urine-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Serotonergic synapse+Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Glutamatergic synapse+Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Gap junction+Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Long-term depression+Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Odoribacter	IP-10	Odoribacter-Serotonergic synapse+20:4/18:0-PE+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-DS
Actinomyces	IP-10	Actinomyces+Coprococcus+L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.621	0.394	no	no	no	no	no	no	DM-DS
Actinomyces	IP-10	Actinomyces+Coprococcus+Roseburia+IP-10	Indirect	Genus	serum_cytokines	0.621	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool-UDCA+stool-TDCA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool-nutriCA+stool+18:0/20:2-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool-nutriCA+stool+18:0/18:1-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/16:1-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool-nutriCA+stool+18:0/18:0-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+L-Phenylalanine+stool-16:0/20:3-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool-nutriCA+stool+16:0/20:3-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/20:3-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool-UDCA+stool+16:0/20:3-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool-nutriCA+stool+18:0/20:3-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool-nutriCA+stool-AA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+Phenylacetic acid+stool-L-Tyrosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool-UDCA+stool+L-Tyrosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+L-Phenylalanine+stool+Homovanillic acid+urine-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool-nutriCA+stool+20:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+Phenylacetic acid+stool-20:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool-nutriCA+stool+20:2/18:0-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool-UDCA+stool-GDCA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	IP-10	2-hydroxyphenylacetic acid+urine+Homovanillic acid+urine-IP-10	Indirect	urine_cometabolism	serum_cytokines	0.763	0.394	no	no	no	no	no	no	DM-DS
Kynurenic acid+stool	IP-10	Kynurenic acid+stool+L-Phenylalanine+stool+Homovanillic acid+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IP-10	Kynurenic acid+stool-nutriCA+stool+16:0/20:3-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IP-10	Kynurenic acid+stool+L-Phenylalanine+stool-16:0/20:3-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IP-10	Kynurenic acid+stool-nutriCA+stool-AA+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IP-10	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IP-10	Kynurenic acid+stool-nutriCA+stool+18:0/18:0-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IP-10	Kynurenic acid+stool-nutriCA+stool+18:0/20:2-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IP-10	Kynurenic acid+stool-nutriCA+stool+18:0/18:1-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IP-10	Kynurenic acid+stool-nutriCA+stool+20:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IP-10	Kynurenic acid+stool-nutriCA+stool+20:2/18:0-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	DM-DS
Caproic acid+stool	IP-10	Caproic acid+stool+Phenylacetic acid+stool-20:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.882	0.394	no	no	no	no	no	no	DM-DS
Caproic acid+stool	IP-10	Caproic acid+stool+Phenylacetic acid+stool-16:0/16:1-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.882	0.394	no	no	no	no	no	no	DM-DS
Caproic acid+stool	IP-10	Caproic acid+stool-GCA+stool-GDCA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.882	0.394	no	no	no	no	no	no	DM-DS
Caproic acid+stool	IP-10	Caproic acid+stool+Phenylacetic acid+stool-16:0/20:3-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.882	0.394	no	no	no	no	no	no	DM-DS
Caproic acid+stool	IP-10	Caproic acid+stool+Phenylacetic acid+stool-L-Tyrosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.882	0.394	no	no	no	no	no	no	DM-DS
Caproic acid+stool	IP-10	Caproic acid+stool-GCA+stool+L-Tyrosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.882	0.394	no	no	no	no	no	no	DM-DS
Caproic acid+stool	IP-10	Caproic acid+stool-GCA+stool+GDCA+stool+IP-10	Indirect	stool_scfa	serum_cytokines	0.882	0.394	no	no	no	no	no	no	DM-DS
Eggerthella	IP-10	Eggerthella+24:1+blood-d18:0-24:1-SM+blood+IP-10	Indirect	Genus	serum_cytokines	0.912	0.394	no	no	no	no	no	no	DM-DS
Eggerthella	IP-10	Eggerthella+Phosphatidylinositol signaling system-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.912	0.394	no	no	no	no	no	no	DM-DS
Eggerthella	IP-10	Eggerthella+nutriCA+stool+20:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.912	0.394	no	no	no	no	no	no	DM-DS
Eggerthella	IP-10	Eggerthella+nutriCA+stool+20:2/18:0-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.912	0.394	no	no	no	no	no	no	DM-DS
Eggerthella	IP-10	Eggerthella+nutriCA+stool+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.912	0.394	no	no	no	no	no	no	DM-DS
Eggerthella	IP-10	Eggerthella+nutriCA+stool-AA+blood-IP-10	Indirect	Genus	serum_cytokines	0.912	0.394	no	no	no	no	no	no	DM-DS
Eggerthella	IP-10	Eggerthella+AMPK signaling pathway-CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.912	0.394	no	no	no	no	no	no	DM-DS
Eggerthella	IP-10	Eggerthella+nutriCA+stool+18:0/18:0-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.912	0.394	no	no	no	no	no	no	DM-DS
Eggerthella	IP-10	Eggerthella+nutriCA+stool+18:0/18:1-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.912	0.394	no	no	no	no	no	no	DM-DS
Eggerthella	IP-10	Eggerthella+nutriCA+stool+18:0/20:2-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.912	0.394	no	no	no	no	no	no	DM-DS
Eggerthella	IP-10	Eggerthella+AMPK signaling pathway+TDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.912	0.394	no	no	no	no	no	no	DM-DS
Eggerthella	IP-10	Eggerthella+nutriCA+stool+18:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.912	0.394	no	no	no	no	no	no	DM-DS
Anaerotruncus	IP-10	Anaerotruncus-Ruminococcus+IP-10	Indirect	Genus	serum_cytokines	0.904	0.394	no	no	no	no	no	no	DM-DS
Anaerostipes	IP-10	Anaerostipes-Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.568	0.394	no	no	no	no	no	no	DM-DS
Anaerostipes	IP-10	Anaerostipes-TDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.568	0.394	no	no	no	no	no	no	DM-DS
Anaerostipes	IP-10	Anaerostipes-GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.568	0.394	no	no	no	no	no	no	DM-DS
Anaerostipes	IP-10	Anaerostipes-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.568	0.394	no	no	no	no	no	no	DM-DS
TUDCA+stool	IP-10	TUDCA+stool+9-HODE+blood+AA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.241	0.394	no	no	no	no	no	no	DM-DS
TUDCA+stool	IP-10	TUDCA+stool-d18:1-14:0-SM+blood+d18:1-22:0-SM+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.241	0.394	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool-UDCA+stool-GDCA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool-UDCA+stool-TDCA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+Phenylacetic acid+stool-20:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+Phenylacetic acid+stool-L-Tyrosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool-UDCA+stool+L-Tyrosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+L-Phenylalanine+stool+Homovanillic acid+urine-IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/16:1-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+L-Phenylalanine+stool-16:0/20:3-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/20:3-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool-UDCA+stool+16:0/20:3-PC+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-DS
Paraprevotella	IP-10	Paraprevotella+IP-10	Direct	Genus	serum_cytokines	0.118	0.394	no	no	no	no	no	no	DM-DS
Homovanillic acid+urine	IP-10	Homovanillic acid+urine-IP-10	Direct	urine_cometabolism	serum_cytokines	0.45	0.394	no	no	no	no	no	no	DM-DS
TDCA+blood	IP-10	TDCA+blood-IP-10	Direct	serum_bileacids	serum_cytokines	0.155	0.394	no	up	no	no	no	no	DM-DS
¦Ø-MCA+stool	IP-10	¦Ø-MCA+stool+GDCA+stool+IP-10	Indirect	stool_bileacids	serum_cytokines	0.919	0.394	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	IP-10	¦Ø-MCA+stool+CDCA+stool+IP-10	Indirect	stool_bileacids	serum_cytokines	0.919	0.394	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IP-10	Phenylacetic acid+stool-16:0/20:3-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.785	0.394	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IP-10	Phenylacetic acid+stool-16:0/16:1-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.785	0.394	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IP-10	Phenylacetic acid+stool-L-Tyrosine+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.785	0.394	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IP-10	Phenylacetic acid+stool-20:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.785	0.394	no	no	no	no	no	no	DM-DS
Gemmiger	IP-10	Gemmiger+ErbB signaling pathway-L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.595	0.394	no	no	no	no	no	no	DM-DS
Gemmiger	IP-10	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.595	0.394	no	no	no	no	no	no	DM-DS
Gemmiger	IP-10	Gemmiger+24:0+blood-Homovanillic acid+urine-IP-10	Indirect	Genus	serum_cytokines	0.595	0.394	no	no	no	no	no	no	DM-DS
Gemmiger	IP-10	Gemmiger+Colorectal cancer-Homovanillic acid+urine-IP-10	Indirect	Genus	serum_cytokines	0.595	0.394	no	no	no	no	no	no	DM-DS
Gemmiger	IP-10	Gemmiger+Gastric cancer-Homovanillic acid+urine-IP-10	Indirect	Genus	serum_cytokines	0.595	0.394	no	no	no	no	no	no	DM-DS
Gemmiger	IP-10	Gemmiger+Signaling pathways regulating pluripotency of stem cells-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.595	0.394	no	no	no	no	no	no	DM-DS
Gemmiger	IP-10	Gemmiger+Pathways in cancer-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.595	0.394	no	no	no	no	no	no	DM-DS
Gemmiger	IP-10	Gemmiger+ErbB signaling pathway-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.595	0.394	no	no	no	no	no	no	DM-DS
Gemmiger	IP-10	Gemmiger+Gastric cancer-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.595	0.394	no	no	no	no	no	no	DM-DS
GDCA+stool	IP-10	GDCA+stool+IP-10	Direct	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	DM-DS
Methanobrevibacter	IP-10	Methanobrevibacter-Alcoholism-IP-10	Indirect	Genus	serum_cytokines	0.629	0.394	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IP-10	L-Tyrosine+stool-nutriCA+stool+20:2/18:0-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IP-10	L-Tyrosine+stool-nutriCA+stool+20:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IP-10	L-Tyrosine+stool-nutriCA+stool+18:0/18:1-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IP-10	L-Tyrosine+stool-nutriCA+stool+18:0/18:0-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IP-10	L-Tyrosine+stool-nutriCA+stool+16:0/20:3-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IP-10	L-Tyrosine+stool-nutriCA+stool+18:0/20:2-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IP-10	L-Tyrosine+stool+9-HODE+blood+AA+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IP-10	L-Tyrosine+stool-nutriCA+stool-AA+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IP-10	L-Tyrosine+stool-nutriCA+stool+18:0/20:3-PC+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	DM-DS
CDCA+stool	IP-10	CDCA+stool+IP-10	Direct	stool_bileacids	serum_cytokines	0.663	0.394	no	no	no	no	no	no	DM-DS
CA+stool	IP-10	CA+stool+16:0/20:3-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.827	0.394	no	no	no	no	no	no	DM-DS
CA+stool	IP-10	CA+stool+GDCA+stool+IP-10	Indirect	stool_bileacids	serum_cytokines	0.827	0.394	no	no	no	no	no	no	DM-DS
CA+stool	IP-10	CA+stool+L-Tyrosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.827	0.394	no	no	no	no	no	no	DM-DS
CA+stool	IP-10	CA+stool+CDCA+stool+IP-10	Indirect	stool_bileacids	serum_cytokines	0.827	0.394	no	no	no	no	no	no	DM-DS
HDCA+blood	IP-10	HDCA+blood+Hypotaurine+blood+iso-DCA+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.483	0.394	no	no	no	no	no	no	DM-DS
UDCA+stool	IP-10	UDCA+stool-GDCA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.266	0.394	no	no	no	no	no	no	DM-DS
UDCA+stool	IP-10	UDCA+stool+L-Tyrosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.266	0.394	no	no	no	no	no	no	DM-DS
UDCA+stool	IP-10	UDCA+stool+16:0/20:3-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.266	0.394	no	no	no	no	no	no	DM-DS
UDCA+stool	IP-10	UDCA+stool-TDCA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.266	0.394	no	no	no	no	no	no	DM-DS
TDCA+stool	IP-10	TDCA+stool-12-ketoDCA+blood+d18:1-22:0-SM+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.963	0.394	no	no	no	no	no	no	DM-DS
TDCA+stool	IP-10	TDCA+stool-12-ketoDCA+blood+d18:0-24:1-SM+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.963	0.394	no	no	no	no	no	no	DM-DS
TDCA+stool	IP-10	TDCA+stool-12-ketoDCA+blood-20:4/18:0-PE+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.963	0.394	no	no	no	no	no	no	DM-DS
TDCA+stool	IP-10	TDCA+stool-12-ketoDCA+blood+GDCA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.963	0.394	no	no	no	no	no	no	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	IP-10	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2-IP-10	Indirect	urine_cometabolism	serum_cytokines	0.973	0.394	no	no	no	no	no	no	DM-DS
Desulfovibrio	IP-10	Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.27	0.394	no	no	no	no	no	no	DM-DS
Desulfovibrio	IP-10	Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.27	0.394	no	no	no	no	no	no	DM-DS
Desulfovibrio	IP-10	Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.27	0.394	no	no	no	no	no	no	DM-DS
Desulfovibrio	IP-10	Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.27	0.394	no	no	no	no	no	no	DM-DS
Desulfovibrio	IP-10	Desulfovibrio+Human T-cell leukemia virus 1 infection+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.27	0.394	no	no	no	no	no	no	DM-DS
Desulfovibrio	IP-10	Desulfovibrio+Human cytomegalovirus infection+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.27	0.394	no	no	no	no	no	no	DM-DS
Desulfovibrio	IP-10	Desulfovibrio+Human immunodeficiency virus 1 infection+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.27	0.394	no	no	no	no	no	no	DM-DS
Desulfovibrio	IP-10	Desulfovibrio+Antigen processing and presentation+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.27	0.394	no	no	no	no	no	no	DM-DS
Desulfovibrio	IP-10	Desulfovibrio+Herpes simplex virus 1 infection+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.27	0.394	no	no	no	no	no	no	DM-DS
Desulfovibrio	IP-10	Desulfovibrio+Antigen processing and presentation+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.27	0.394	no	no	no	no	no	no	DM-DS
nutriCA+stool	IP-10	nutriCA+stool+18:0/18:1-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	DM-DS
nutriCA+stool	IP-10	nutriCA+stool+18:0/18:0-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	DM-DS
nutriCA+stool	IP-10	nutriCA+stool-AA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	DM-DS
nutriCA+stool	IP-10	nutriCA+stool+20:2/18:0-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	DM-DS
nutriCA+stool	IP-10	nutriCA+stool+16:0/20:3-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	DM-DS
nutriCA+stool	IP-10	nutriCA+stool+18:0/20:3-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	DM-DS
nutriCA+stool	IP-10	nutriCA+stool+18:0/20:2-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	DM-DS
nutriCA+stool	IP-10	nutriCA+stool+20:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	DM-DS
Bilophila	IP-10	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.528	0.394	no	no	no	no	no	no	DM-DS
Bilophila	IP-10	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.528	0.394	no	no	no	no	no	no	DM-DS
Bilophila	IP-10	Bilophila+Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.528	0.394	no	no	no	no	no	no	DM-DS
Bilophila	IP-10	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.528	0.394	no	no	no	no	no	no	DM-DS
Bilophila	IP-10	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.528	0.394	no	no	no	no	no	no	DM-DS
Bilophila	IP-10	Bilophila+Desulfovibrio+Human cytomegalovirus infection+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.528	0.394	no	no	no	no	no	no	DM-DS
Bilophila	IP-10	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.528	0.394	no	no	no	no	no	no	DM-DS
Bilophila	IP-10	Bilophila+Desulfovibrio+Antigen processing and presentation+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.528	0.394	no	no	no	no	no	no	DM-DS
Bilophila	IP-10	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+16:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.528	0.394	no	no	no	no	no	no	DM-DS
Bilophila	IP-10	Bilophila+Desulfovibrio+Antigen processing and presentation+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.528	0.394	no	no	no	no	no	no	DM-DS
GDCA+blood	IP-10	GDCA+blood-IP-10	Direct	serum_bileacids	serum_cytokines	0.632	0.394	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	IP-10	P-hydroxyhippuric acid+urine+Eotaxin-IL-6-IP-10	Indirect	urine_cometabolism	serum_cytokines	0.436	0.394	no	no	no	no	no	no	DM-DS
acetic acid C2+blood	IP-10	acetic acid C2+blood+d18:1-18:1-SM+blood+Homovanillic acid+urine-IP-10	Indirect	serum_scfa	serum_cytokines	0.000193	0.394	up	dn	no	no	no	no	DM-DS
acetic acid C2+blood	IP-10	acetic acid C2+blood+d18:1-20:1-SM+blood+Homovanillic acid+urine-IP-10	Indirect	serum_scfa	serum_cytokines	0.000193	0.394	up	dn	no	no	no	no	DM-DS
acetic acid C2+blood	IP-10	acetic acid C2+blood+d18:1-20:1-SM+blood-L-Tyrosine+blood+IP-10	Indirect	serum_scfa	serum_cytokines	0.000193	0.394	up	dn	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	IP-10	isovaleric acid iso-C5+blood-L-Phenylalanine+blood+L-Tyrosine+blood+IP-10	Indirect	serum_scfa	serum_cytokines	0.117	0.394	no	no	no	no	no	no	DM-DS
Clostridium	IP-10	Clostridium+GDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.925	0.394	no	no	no	no	no	no	DM-DS
Clostridium	IP-10	Clostridium-GDCA+blood-IP-10	Indirect	Genus	serum_cytokines	0.925	0.394	no	no	no	no	no	no	DM-DS
Clostridium	IP-10	Clostridium+CDCA+stool+IP-10	Indirect	Genus	serum_cytokines	0.925	0.394	no	no	no	no	no	no	DM-DS
Clostridium	IP-10	Clostridium+20:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.925	0.394	no	no	no	no	no	no	DM-DS
Clostridium	IP-10	Clostridium+18:0/20:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.925	0.394	no	no	no	no	no	no	DM-DS
Clostridium	IP-10	Clostridium+20:2/18:0-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.925	0.394	no	no	no	no	no	no	DM-DS
Clostridium	IP-10	Clostridium+Homovanillic acid+urine-IP-10	Indirect	Genus	serum_cytokines	0.925	0.394	no	no	no	no	no	no	DM-DS
Clostridium	IP-10	Clostridium+IL-6-IP-10	Indirect	Genus	serum_cytokines	0.925	0.394	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	IP-10	T-¦Á-MCA+stool-UDCA+stool-TDCA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.48	0.394	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	IP-10	T-¦Á-MCA+stool-UDCA+stool+L-Tyrosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.48	0.394	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	IP-10	T-¦Á-MCA+stool-UDCA+stool+16:0/20:3-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.48	0.394	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	IP-10	T-¦Á-MCA+stool-UDCA+stool-GDCA+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.48	0.394	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IP-10	12-ketoDCA+blood+GDCA+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IP-10	12-ketoDCA+blood+d18:0-24:1-SM+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-20:4/18:0-PE+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IP-10	12-ketoDCA+blood+d18:1-22:0-SM+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood+18:1/18:1-PE+blood+20:3n6+blood+IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood+16:0/18:1-PE+blood+20:3n6+blood+IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood+18:1/18:0-PE+blood+20:3n6+blood+IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood+18:1/16:1-PE+blood+20:3n6+blood+IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood+20:3n6+blood+IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood-20:0+blood-Homovanillic acid+urine-IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	Butyricicoccus-18:2/20:4-PC+blood+20:0+blood-Homovanillic acid+urine-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood+9,10-EPOME+blood+Homovanillic acid+urine-IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood-d18:1-20:1-SM+blood+Homovanillic acid+urine-IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood+18:1/18:1-PE+blood+20:4/18:0-PE+blood-IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood+18:1/18:1-PE+blood-AA+blood-IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood+16:0/18:1-PE+blood-AA+blood-IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood+18:1/18:0-PE+blood-AA+blood-IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	Butyricicoccus-18:2/20:4-PC+blood+20:4-LPC+blood+AA+blood-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood+18:1/16:1-PE+blood-AA+blood-IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	Butyricicoccus-18:2/20:4-PC+blood+20:3/16:0-PC+blood+AA+blood-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood-AA+blood-IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	Butyricicoccus+TUDCA+stool+9-HODE+blood+AA+blood-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	Butyricicoccus+TUDCA+stool-d18:1-14:0-SM+blood+d18:1-22:0-SM+blood+IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood-20:0-LPC+blood+d18:1-22:0-SM+blood+IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	Butyricicoccus-18:2/20:4-PC+blood+20:0-LPC+blood+d18:1-22:0-SM+blood+IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood-d18:1-20:0-SM+blood+d18:1-22:0-SM+blood+IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	Butyricicoccus-18:2/20:4-PC+blood-L-Phenylalanine+blood+L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood-20:1-LPE+blood-L-Tyrosine+blood+IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	Butyricicoccus-18:2/20:4-PC+blood+20:4n6+blood-L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	Butyricicoccus-18:2/20:4-PC+blood+20:4-LPC+blood-L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood-20:0+blood-L-Tyrosine+blood+IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	Butyricicoccus-18:2/20:4-PC+blood+20:0+blood-L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood-20:4-LPE+blood-L-Tyrosine+blood+IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	Butyricicoccus-18:2/20:4-PC+blood+20:4-LPE+blood-L-Tyrosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood-d18:1-20:1-SM+blood-L-Tyrosine+blood+IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	Butyricicoccus-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood+18:0/20:3-PC+blood+IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood-20:1-LPE+blood+d18:0-24:1-SM+blood+IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood-20:0-LPC+blood+d18:0-24:1-SM+blood+IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	Butyricicoccus-18:2/20:4-PC+blood+20:0-LPC+blood+d18:0-24:1-SM+blood+IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Butyricicoccus	IP-10	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood+20:2/18:0-PC+blood+IP-10"	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-DS
Blautia	IL-1b	Blautia+Dorea-Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia+Longevity regulating pathway - multiple species-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia+Longevity regulating pathway - multiple species+Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia+Peroxisome+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia+d18:1-18:0-SM+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia-Calcium signaling pathway-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia+Peroxisome+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia+Peroxisome+Apoptosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia+Peroxisome+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia-Dopaminergic synapse-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia+Peroxisome-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia-Dopaminergic synapse+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia+Peroxisome+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia-Dopaminergic synapse-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia-Dopaminergic synapse-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia+Longevity regulating pathway - multiple species-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia-Dopaminergic synapse-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia+CDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia-Dopaminergic synapse-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia-Calcium signaling pathway-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia-Calcium signaling pathway-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Blautia	IL-1b	Blautia+Dorea-Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-DS
Parabacteroides	IL-1b	Parabacteroides-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.00358	no	up	up	up	up	no	DM-DS
Dorea	IL-1b	Dorea-Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	DM-DS
Dorea	IL-1b	Dorea-Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	DM-DS
Faecalibacterium	IL-1b	Faecalibacterium-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0039	0.00358	no	dn	dn	up	up	no	DM-DS
Faecalibacterium	IL-1b	Faecalibacterium+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0039	0.00358	no	dn	dn	up	up	no	DM-DS
Bacteroides	IL-1b	Bacteroides-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.000267	0.00358	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-1b	Bacteroides-cAMP signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.000267	0.00358	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-1b	Bacteroides+16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.000267	0.00358	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-1b	Bacteroides-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.000267	0.00358	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-1b	Bacteroides-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.000267	0.00358	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-1b	Bacteroides-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.000267	0.00358	dn	dn	up	up	up	no	DM-DS
Bacteroides	IL-1b	Bacteroides-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.000267	0.00358	dn	dn	up	up	up	no	DM-DS
Propionic acid+stool	IL-1b	Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.00358	dn	no	up	up	up	no	DM-DS
Propionic acid+stool	IL-1b	Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.00358	dn	no	up	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Shigellosis-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-18:0/20:4-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-18:1/20:4-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-18:0/20:5-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Tight junction-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-ErbB signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-JAK-STAT signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-MicroRNAs in cancer+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-Pathways in cancer+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-ErbB signaling pathway-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-ErbB signaling pathway+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-JAK-STAT signaling pathway+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Huntington disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Non-alcoholic fatty liver disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-MicroRNAs in cancer+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-Pathways in cancer+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Alzheimer disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Parkinson disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-ErbB signaling pathway+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-JAK-STAT signaling pathway+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-JAK-STAT signaling pathway+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Huntington disease-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Non-alcoholic fatty liver disease-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Alzheimer disease-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Parkinson disease-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Tight junction-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-JAK-STAT signaling pathway+Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-Gastric cancer-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-Platinum drug resistance+Ribosome biogenesis in eukaryotes-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Tight junction-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-ErbB signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-JAK-STAT signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-FoxO signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-ErbB signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-JAK-STAT signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Tight junction-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-ErbB signaling pathway+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-JAK-STAT signaling pathway+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-MicroRNAs in cancer+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-Pathways in cancer+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Tight junction-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-ErbB signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-JAK-STAT signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Tight junction-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-FoxO signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-ErbB signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-JAK-STAT signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Huntington disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Non-alcoholic fatty liver disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-MicroRNAs in cancer+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-Pathways in cancer+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Alzheimer disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Parkinson disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-18:0/20:4-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+18:0/18:1-PE+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Tight junction-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-FoxO signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-ErbB signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-JAK-STAT signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Huntington disease-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+Alzheimer disease-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-Progesterone-mediated oocyte maturation+Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-Platinum drug resistance+Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-Progesterone-mediated oocyte maturation-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]-Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
[Ruminococcus]	IL-1b	[Ruminococcus]+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-DS
GUDCA+blood	IL-1b	GUDCA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00358	no	no	dn	up	up	no	DM-DS
GUDCA+blood	IL-1b	GUDCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00358	no	no	dn	up	up	no	DM-DS
UDCA+blood	IL-1b	UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0939	0.00358	no	no	dn	up	up	no	DM-DS
UDCA+blood	IL-1b	UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0939	0.00358	no	no	dn	up	up	no	DM-DS
Acetic acid+stool	IL-1b	Acetic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_scfa	serum_cytokines	0.0656	0.00358	dn	no	no	up	up	no	DM-DS
Acetic acid+stool	IL-1b	Acetic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.0656	0.00358	dn	no	no	up	up	no	DM-DS
Acetic acid+stool	IL-1b	Acetic acid+stool-16:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.0656	0.00358	dn	no	no	up	up	no	DM-DS
Acetic acid+stool	IL-1b	Acetic acid+stool-18:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.0656	0.00358	dn	no	no	up	up	no	DM-DS
Acetic acid+stool	IL-1b	Acetic acid+stool+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.0656	0.00358	dn	no	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Vibrio cholerae infection-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+T cell receptor signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Platelet activation-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Ferroptosis+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+Platinum drug resistance+Ribosome biogenesis in eukaryotes-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Influenza A-Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+MAPK signaling pathway+Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+Platinum drug resistance+Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Rap1 signaling pathway-Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Ferroptosis-Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Ferroptosis+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Ferroptosis+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+T cell receptor signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-18:2/16:0-PC+blood+18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+18:0-LPC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+T cell receptor signaling pathway-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Vibrio cholerae infection-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+T cell receptor signaling pathway+Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Platelet activation-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Oxytocin signaling pathway-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Salivary secretion-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Alcoholism+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Ferroptosis+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Vibrio cholerae infection-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+T cell receptor signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+Signaling pathways regulating pluripotency of stem cells+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Platelet activation-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Oxytocin signaling pathway-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Salivary secretion-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+Colorectal cancer-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+Signaling pathways regulating pluripotency of stem cells-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+Gastric cancer-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+T cell receptor signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Platelet activation-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+MAPK signaling pathway-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Vibrio cholerae infection-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+T cell receptor signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+Signaling pathways regulating pluripotency of stem cells+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Platelet activation-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Oxytocin signaling pathway-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Rap1 signaling pathway-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Salivary secretion-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Vibrio cholerae infection-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+T cell receptor signaling pathway+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+Signaling pathways regulating pluripotency of stem cells+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Platelet activation-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Oxytocin signaling pathway-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Salivary secretion-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes+MAPK signaling pathway+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-DMG+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Platelet activation-Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Oxytocin signaling pathway-Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Rap1 signaling pathway-Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Platelet activation-Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Oxytocin signaling pathway-Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Alistipes	IL-1b	Alistipes-Rap1 signaling pathway-Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-DS
Butyricimonas	IL-1b	Butyricimonas+Cholinergic synapse-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.17	0.00358	no	no	no	up	up	no	DM-DS
Butyricimonas	IL-1b	Butyricimonas+20:5n3+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.17	0.00358	no	no	no	up	up	no	DM-DS
Butyricimonas	IL-1b	Butyricimonas+Cholinergic synapse+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.17	0.00358	no	no	no	up	up	no	DM-DS
Collinsella	IL-1b	Collinsella-Renin secretion-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-DS
Collinsella	IL-1b	Collinsella-Inflammatory mediator regulation of TRP channels-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-DS
Collinsella	IL-1b	Collinsella-Renin secretion-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-DS
Collinsella	IL-1b	Collinsella-Inflammatory mediator regulation of TRP channels-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-DS
Collinsella	IL-1b	Collinsella-Inflammatory mediator regulation of TRP channels+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-DS
Collinsella	IL-1b	Collinsella-Renin secretion-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-DS
Collinsella	IL-1b	Collinsella-Inflammatory mediator regulation of TRP channels-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-DS
Collinsella	IL-1b	Collinsella-Renin secretion-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-DS
Collinsella	IL-1b	Collinsella-Inflammatory mediator regulation of TRP channels-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-DS
Collinsella	IL-1b	Collinsella-Renin secretion-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-DS
Collinsella	IL-1b	Collinsella-Inflammatory mediator regulation of TRP channels-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-DS
Collinsella	IL-1b	Collinsella-Renin secretion-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-DS
Collinsella	IL-1b	Collinsella-Inflammatory mediator regulation of TRP channels-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-DS
Collinsella	IL-1b	Collinsella-Renin secretion-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-DS
Collinsella	IL-1b	Collinsella-Inflammatory mediator regulation of TRP channels-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-DS
Sarcina	IL-1b	Sarcina+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0703	0.00358	no	no	no	up	up	no	DM-DS
Methanosphaera	IL-1b	Methanosphaera-Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0703	0.00358	no	no	no	up	up	no	DM-DS
Methanosphaera	IL-1b	Methanosphaera-Roseburia+16:0/16:1-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0703	0.00358	no	no	no	up	up	no	DM-DS
Methanosphaera	IL-1b	Methanosphaera-Roseburia+16:0/16:1-PC+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0703	0.00358	no	no	no	up	up	no	DM-DS
Methanosphaera	IL-1b	Methanosphaera-Roseburia+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0703	0.00358	no	no	no	up	up	no	DM-DS
Methanosphaera	IL-1b	Methanosphaera-Roseburia+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0703	0.00358	no	no	no	up	up	no	DM-DS
Methanosphaera	IL-1b	Methanosphaera-Roseburia+16:0/16:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0703	0.00358	no	no	no	up	up	no	DM-DS
Methanosphaera	IL-1b	Methanosphaera-Roseburia+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0703	0.00358	no	no	no	up	up	no	DM-DS
Methanosphaera	IL-1b	Methanosphaera-Roseburia-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0703	0.00358	no	no	no	up	up	no	DM-DS
Methanosphaera	IL-1b	Methanosphaera-Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0703	0.00358	no	no	no	up	up	no	DM-DS
iso-DCA+stool	IL-1b	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.00358	no	no	no	up	up	no	DM-DS
iso-DCA+stool	IL-1b	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.00358	no	no	no	up	up	no	DM-DS
LCA+stool	IL-1b	LCA+stool-UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	DM-DS
LCA+stool	IL-1b	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	DM-DS
LCA+stool	IL-1b	LCA+stool-UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	DM-DS
Akkermansia	IL-1b	Akkermansia+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-DS
Akkermansia	IL-1b	Akkermansia+Proteoglycans in cancer-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-DS
Akkermansia	IL-1b	Akkermansia-Cholinergic synapse-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-DS
Akkermansia	IL-1b	Akkermansia-Cholinergic synapse+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-DS
Akkermansia	IL-1b	Akkermansia-Cytokine-cytokine receptor interaction+16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-DS
Akkermansia	IL-1b	Akkermansia+Proteoglycans in cancer-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-DS
Akkermansia	IL-1b	Akkermansia-Cytokine-cytokine receptor interaction-Cytosolic DNA-sensing pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-DS
Akkermansia	IL-1b	Akkermansia+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Glutamatergic synapse+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Gastric acid secretion-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Autophagy - animal+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+HIF-1 signaling pathway-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Proteasome-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-GABAergic synapse+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Proteoglycans in cancer-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Transcriptional misregulation in cancer+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Hepatitis B+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Glycolysis / Gluconeogenesis-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-MicroRNAs in cancer+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Focal adhesion-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Hippo signaling pathway-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Autophagy - animal+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+HIF-1 signaling pathway-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Proteasome-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Tight junction-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Glycolysis / Gluconeogenesis-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Focal adhesion-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Hippo signaling pathway-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Adherens junction-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Autophagy - animal+Apoptosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+HIF-1 signaling pathway-Apoptosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Proteasome-Apoptosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Glycolysis / Gluconeogenesis-Apoptosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Autophagy - animal+Cytosolic DNA-sensing pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Focal adhesion-Cytosolic DNA-sensing pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Autophagy - animal+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+HIF-1 signaling pathway-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Proteasome-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-FoxO signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Glycolysis / Gluconeogenesis-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Focal adhesion-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Hippo signaling pathway-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Adherens junction-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Autophagy - animal+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Proteasome-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Tight junction-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Glycolysis / Gluconeogenesis-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Focal adhesion-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Hippo signaling pathway-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Adherens junction-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-18:0/20:4-PI+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+DMG+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Glutamatergic synapse+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Autophagy - animal+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+HIF-1 signaling pathway-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Proteasome-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Glycolysis / Gluconeogenesis-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Focal adhesion-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Hippo signaling pathway-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Vibrio cholerae infection-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Gastric acid secretion-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Autophagy - animal+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Proteasome-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Transcriptional misregulation in cancer+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Tight junction-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Hepatitis B+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Bacterial invasion of epithelial cells-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Glycolysis / Gluconeogenesis-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-MicroRNAs in cancer+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Focal adhesion-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Hippo signaling pathway-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Adherens junction-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Vibrio cholerae infection-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Gastric acid secretion-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Autophagy - animal+Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Tight junction-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Focal adhesion-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Hippo signaling pathway-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Adherens junction-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Vibrio cholerae infection-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Gastric acid secretion-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Autophagy - animal+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Proteasome-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Transcriptional misregulation in cancer+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Tight junction-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Hepatitis B+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Bacterial invasion of epithelial cells-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Glycolysis / Gluconeogenesis-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-MicroRNAs in cancer+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Focal adhesion-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Hippo signaling pathway-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Adherens junction-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Vibrio cholerae infection-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Thyroid hormone signaling pathway-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Gastric acid secretion-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Autophagy - animal+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+HIF-1 signaling pathway-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Proteasome-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-GABAergic synapse+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-FoxO signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Proteoglycans in cancer-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Transcriptional misregulation in cancer+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Tight junction-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Hepatitis B+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Bacterial invasion of epithelial cells-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Glycolysis / Gluconeogenesis-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-MicroRNAs in cancer+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Focal adhesion-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Hippo signaling pathway-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Adherens junction-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Proteasome-cAMP signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Glycolysis / Gluconeogenesis-cAMP signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Autophagy - animal-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Proteasome+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-GABAergic synapse-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Focal adhesion+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Hippo signaling pathway+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Glutamatergic synapse+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Autophagy - animal+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+HIF-1 signaling pathway-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Proteasome-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-GABAergic synapse+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Glycolysis / Gluconeogenesis-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Hippo signaling pathway-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Leukocyte transendothelial migration-Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Glutamatergic synapse+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Vibrio cholerae infection-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Thyroid hormone signaling pathway-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Gastric acid secretion-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-Autophagy - animal+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+HIF-1 signaling pathway-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Proteasome-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-GABAergic synapse+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium-FoxO signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Tight junction-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Bacterial invasion of epithelial cells-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Glycolysis / Gluconeogenesis-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Focal adhesion-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Hippo signaling pathway-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Adherens junction-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Leukocyte transendothelial migration-Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Bifidobacterium	IL-1b	Bifidobacterium+Leukocyte transendothelial migration-Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-DS
Ruminococcus	IL-1b	Ruminococcus-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	DM-DS
Ruminococcus	IL-1b	Ruminococcus-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	DM-DS
GCDCA+blood	IL-1b	GCDCA+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.00358	no	no	no	up	up	no	DM-DS
ACA+blood	IL-1b	ACA+blood+EPA+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.338	0.00358	no	no	no	up	up	no	DM-DS
ACA+blood	IL-1b	ACA+blood-decanoic acid C10+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.338	0.00358	no	no	no	up	up	no	DM-DS
DCA+stool	IL-1b	DCA+stool+HDCA+stool+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	DM-DS
DCA+stool	IL-1b	DCA+stool+HDCA+stool+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	DM-DS
Butyric acid+stool	IL-1b	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.00358	dn	no	no	up	up	no	DM-DS
Butyric acid+stool	IL-1b	Butyric acid+stool+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.00358	dn	no	no	up	up	no	DM-DS
Butyric acid+stool	IL-1b	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.00358	dn	no	no	up	up	no	DM-DS
Butyric acid+stool	IL-1b	Butyric acid+stool+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.00358	dn	no	no	up	up	no	DM-DS
Butyric acid+stool	IL-1b	Butyric acid+stool-16:0/20:5-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.00358	dn	no	no	up	up	no	DM-DS
Butyric acid+stool	IL-1b	Butyric acid+stool+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.00358	dn	no	no	up	up	no	DM-DS
4-hydroxybenzoic acid+stool	IL-1b	4-hydroxybenzoic acid+stool-DCA+stool+HDCA+stool+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.00358	no	dn	no	up	up	no	DM-DS
4-hydroxybenzoic acid+stool	IL-1b	4-hydroxybenzoic acid+stool-iso-LCA+stool-TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.00358	no	dn	no	up	up	no	DM-DS
4-hydroxybenzoic acid+stool	IL-1b	4-hydroxybenzoic acid+stool-iso-LCA+stool-TCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.00358	no	dn	no	up	up	no	DM-DS
4-hydroxybenzoic acid+stool	IL-1b	4-hydroxybenzoic acid+stool-DCA+stool+HDCA+stool+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.00358	no	dn	no	up	up	no	DM-DS
Turicibacter	IL-1b	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.269	0.00358	no	no	no	up	up	no	DM-DS
Turicibacter	IL-1b	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.269	0.00358	no	no	no	up	up	no	DM-DS
Turicibacter	IL-1b	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.269	0.00358	no	no	no	up	up	no	DM-DS
Turicibacter	IL-1b	Turicibacter+Desulfovibrio+Antigen processing and presentation+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.269	0.00358	no	no	no	up	up	no	DM-DS
Turicibacter	IL-1b	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.269	0.00358	no	no	no	up	up	no	DM-DS
Turicibacter	IL-1b	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.269	0.00358	no	no	no	up	up	no	DM-DS
GCA+blood	IL-1b	GCA+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.16	0.00358	no	no	no	up	up	no	DM-DS
ACA+stool	IL-1b	ACA+stool-L-Phenylalanine+stool-16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.417	0.00358	no	no	no	up	up	no	DM-DS
ACA+stool	IL-1b	ACA+stool-L-Phenylalanine+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.417	0.00358	no	no	no	up	up	no	DM-DS
ACA+stool	IL-1b	ACA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.417	0.00358	no	no	no	up	up	no	DM-DS
ACA+stool	IL-1b	ACA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.417	0.00358	no	no	no	up	up	no	DM-DS
CDCA+blood	IL-1b	CDCA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.00358	no	no	no	up	up	no	DM-DS
CDCA+blood	IL-1b	CDCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.00358	no	no	no	up	up	no	DM-DS
capric acid C6+blood	IL-1b	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.433	0.00358	no	no	no	up	up	no	DM-DS
capric acid C6+blood	IL-1b	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.433	0.00358	no	no	no	up	up	no	DM-DS
Prevotella	IL-1b	Prevotella+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	DM-DS
Prevotella	IL-1b	Prevotella+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	DM-DS
iso-DCA+blood	IL-1b	iso-DCA+blood+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.38	0.00358	no	no	no	up	up	no	DM-DS
iso-DCA+blood	IL-1b	iso-DCA+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.38	0.00358	no	no	no	up	up	no	DM-DS
HCA+stool	IL-1b	HCA+stool-HDCA+stool+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.00358	no	no	no	up	up	no	DM-DS
HCA+stool	IL-1b	HCA+stool-HDCA+stool+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.00358	no	no	no	up	up	no	DM-DS
Roseburia	IL-1b	Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.495	0.00358	no	no	no	up	up	no	DM-DS
Roseburia	IL-1b	Roseburia+16:0/16:1-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.495	0.00358	no	no	no	up	up	no	DM-DS
Roseburia	IL-1b	Roseburia+16:0/16:1-PC+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.495	0.00358	no	no	no	up	up	no	DM-DS
Roseburia	IL-1b	Roseburia+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.495	0.00358	no	no	no	up	up	no	DM-DS
Roseburia	IL-1b	Roseburia+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.495	0.00358	no	no	no	up	up	no	DM-DS
Roseburia	IL-1b	Roseburia+16:0/16:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.495	0.00358	no	no	no	up	up	no	DM-DS
Roseburia	IL-1b	Roseburia+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.495	0.00358	no	no	no	up	up	no	DM-DS
Roseburia	IL-1b	Roseburia-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.495	0.00358	no	no	no	up	up	no	DM-DS
Roseburia	IL-1b	Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.495	0.00358	no	no	no	up	up	no	DM-DS
12-ketoDCA+stool	IL-1b	12-ketoDCA+stool+HDCA+stool+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.00358	no	no	no	up	up	no	DM-DS
12-ketoDCA+stool	IL-1b	12-ketoDCA+stool+HDCA+stool+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.00358	no	no	no	up	up	no	DM-DS
GLCA+blood	IL-1b	GLCA+blood-SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.319	0.00358	no	no	no	up	up	no	DM-DS
GLCA+blood	IL-1b	GLCA+blood-SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.319	0.00358	no	no	no	up	up	no	DM-DS
L-Tryptophan+stool	IL-1b	L-Tryptophan+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00358	no	no	no	up	up	no	DM-DS
L-Tryptophan+stool	IL-1b	L-Tryptophan+stool+8-HETE+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00358	no	no	no	up	up	no	DM-DS
L-Tryptophan+stool	IL-1b	L-Tryptophan+stool-18:3n6+blood-22:0/16:0-PE+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00358	no	no	no	up	up	no	DM-DS
L-Tryptophan+stool	IL-1b	L-Tryptophan+stool-18:3n6+blood-L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00358	no	no	no	up	up	no	DM-DS
L-Tryptophan+stool	IL-1b	L-Tryptophan+stool+8-HETE+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00358	no	no	no	up	up	no	DM-DS
L-Tryptophan+stool	IL-1b	L-Tryptophan+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00358	no	no	no	up	up	no	DM-DS
CA+blood	IL-1b	CA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.606	0.00358	no	no	no	up	up	no	DM-DS
CA+blood	IL-1b	CA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.606	0.00358	no	no	no	up	up	no	DM-DS
GUDCA+stool	IL-1b	GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0085	0.00358	no	dn	no	up	up	no	DM-DS
GUDCA+stool	IL-1b	GUDCA+stool+12-HEPE+blood-DMG+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0085	0.00358	no	dn	no	up	up	no	DM-DS
GUDCA+stool	IL-1b	GUDCA+stool+12-HEPE+blood+16:0/20:5-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0085	0.00358	no	dn	no	up	up	no	DM-DS
GUDCA+stool	IL-1b	GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0085	0.00358	no	dn	no	up	up	no	DM-DS
L-Phenylalanine+stool	IL-1b	L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00358	no	no	no	up	up	no	DM-DS
L-Phenylalanine+stool	IL-1b	L-Phenylalanine+stool-16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00358	no	no	no	up	up	no	DM-DS
L-Phenylalanine+stool	IL-1b	L-Phenylalanine+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00358	no	no	no	up	up	no	DM-DS
L-Phenylalanine+stool	IL-1b	L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00358	no	no	no	up	up	no	DM-DS
GCA+stool	IL-1b	GCA+stool+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus+Roseburia+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus+Roseburia+16:0/16:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus+Roseburia-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus+16:0/16:0-PC+blood+18:0/18:2-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus+16:0/16:0-PC+blood+18:1/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus+Roseburia+16:0/16:1-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus+16:0/16:0-PC+blood-18:0-LPC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus+Roseburia+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus+Roseburia+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus+16:0/16:0-PC+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus+16:0/16:0-PC+blood+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus+Roseburia+16:0/16:1-PC+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus+16:0/16:0-PC+blood+22:0/16:0-PE+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Coprococcus	IL-1b	Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Rap1 signaling pathway-Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Spliceosome+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Platelet activation-Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Calcium signaling pathway-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Calcium signaling pathway-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+JAK-STAT signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Ribosome-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vascular smooth muscle contraction-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Oxidative phosphorylation-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Autophagy - animal+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+NF-kappa B signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Cardiac muscle contraction-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+FoxO signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Focal adhesion-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+JAK-STAT signaling pathway+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Autophagy - animal+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+NF-kappa B signaling pathway+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Focal adhesion-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+JAK-STAT signaling pathway+Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vibrio cholerae infection-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Dopaminergic synapse-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Morphine addiction-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Renin secretion-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vasopressin-regulated water reabsorption-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Melanogenesis-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Inflammatory mediator regulation of TRP channels-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Salivary secretion-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vascular smooth muscle contraction-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+T cell receptor signaling pathway+Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Platelet activation-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Gastric acid secretion-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Autophagy - animal+Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Circadian entrainment-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+NF-kappa B signaling pathway+Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Pancreatic secretion-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Focal adhesion-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Calcium signaling pathway-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Shigellosis-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+MAPK signaling pathway+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+JAK-STAT signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vascular smooth muscle contraction-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+T cell receptor signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Platelet activation-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Autophagy - animal+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Circadian entrainment-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+NF-kappa B signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Focal adhesion-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Thermogenesis+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Dopaminergic synapse+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Inflammatory mediator regulation of TRP channels+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vascular smooth muscle contraction+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+T cell receptor signaling pathway-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Autophagy - animal-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Circadian entrainment+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+NF-kappa B signaling pathway-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Focal adhesion+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Ribosome-Apoptosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Oxidative phosphorylation-Apoptosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Autophagy - animal+Apoptosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+NF-kappa B signaling pathway+Apoptosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+NF-kappa B signaling pathway+Sphingolipid signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Autophagy - animal+Cytosolic DNA-sensing pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+NF-kappa B signaling pathway+Cytosolic DNA-sensing pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Focal adhesion-Cytosolic DNA-sensing pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Thermogenesis-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+JAK-STAT signaling pathway+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Ribosome-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Prion disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Huntington disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Alzheimer disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Coronavirus disease - COVID-19-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Retrograde endocannabinoid signaling-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Renin secretion-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Hepatitis B+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Melanogenesis-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Inflammatory mediator regulation of TRP channels-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vascular smooth muscle contraction-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Oxidative phosphorylation-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Gastric acid secretion-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Autophagy - animal+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Non-alcoholic fatty liver disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Circadian entrainment-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+NF-kappa B signaling pathway+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Pathways of neurodegeneration - multiple diseases-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Cardiac muscle contraction-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Parkinson disease-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Focal adhesion-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Thermogenesis-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+JAK-STAT signaling pathway+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Ribosome-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Prion disease-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Huntington disease-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Alzheimer disease-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Retrograde endocannabinoid signaling-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Renin secretion-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Melanogenesis-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Inflammatory mediator regulation of TRP channels-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Oxidative phosphorylation-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Autophagy - animal+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Non-alcoholic fatty liver disease-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+NF-kappa B signaling pathway+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Pathways of neurodegeneration - multiple diseases-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Cardiac muscle contraction-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Parkinson disease-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Thermogenesis-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+JAK-STAT signaling pathway+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vibrio cholerae infection-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Prion disease-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Dopaminergic synapse-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Retrograde endocannabinoid signaling-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Renin secretion-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Hepatitis B+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vasopressin-regulated water reabsorption-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Melanogenesis-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Inflammatory mediator regulation of TRP channels-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Salivary secretion-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vascular smooth muscle contraction-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+T cell receptor signaling pathway+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Platelet activation-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Oxidative phosphorylation-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Gastric acid secretion-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Autophagy - animal+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Circadian entrainment-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+NF-kappa B signaling pathway+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Focal adhesion-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Thermogenesis-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+JAK-STAT signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vibrio cholerae infection-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Ribosome-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Prion disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Huntington disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Alzheimer disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Dopaminergic synapse-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Coronavirus disease - COVID-19-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Retrograde endocannabinoid signaling-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Renin secretion-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Hepatitis B+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Rap1 signaling pathway-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vasopressin-regulated water reabsorption-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Melanogenesis-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Inflammatory mediator regulation of TRP channels-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Salivary secretion-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vascular smooth muscle contraction-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+T cell receptor signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Platelet activation-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Oxidative phosphorylation-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Gastric acid secretion-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Autophagy - animal+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Non-alcoholic fatty liver disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Circadian entrainment-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+NF-kappa B signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Pathways of neurodegeneration - multiple diseases-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Cardiac muscle contraction-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+FoxO signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Parkinson disease-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Focal adhesion-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+JAK-STAT signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Ribosome-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vascular smooth muscle contraction-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+T cell receptor signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Oxidative phosphorylation-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Autophagy - animal+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+NF-kappa B signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Cardiac muscle contraction-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Focal adhesion-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+JAK-STAT signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vibrio cholerae infection-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Dopaminergic synapse-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Retrograde endocannabinoid signaling-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Renin secretion-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Hepatitis B+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Inflammatory mediator regulation of TRP channels-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Salivary secretion-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vascular smooth muscle contraction-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+T cell receptor signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Platelet activation-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Gastric acid secretion-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Autophagy - animal+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Circadian entrainment-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+NF-kappa B signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Focal adhesion-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Thermogenesis-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+JAK-STAT signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vibrio cholerae infection-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Ribosome-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Prion disease-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Huntington disease-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Alzheimer disease-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Dopaminergic synapse-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Retrograde endocannabinoid signaling-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Renin secretion-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Melanogenesis-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Inflammatory mediator regulation of TRP channels-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Vascular smooth muscle contraction-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+T cell receptor signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Platelet activation-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Oxidative phosphorylation-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Gastric acid secretion-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Autophagy - animal+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Circadian entrainment-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+NF-kappa B signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Cardiac muscle contraction-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+FoxO signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Focal adhesion-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Platinum drug resistance+Ribosome biogenesis in eukaryotes-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Platinum drug resistance+Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Progesterone-mediated oocyte maturation+Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Human cytomegalovirus infection-Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Rap1 signaling pathway-Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Spliceosome+Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+MAPK signaling pathway+Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Progesterone-mediated oocyte maturation-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Human cytomegalovirus infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+MAPK signaling pathway-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Rap1 signaling pathway-Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira+Spliceosome+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
Oscillospira	IL-1b	Oscillospira-Platelet activation-Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-DS
HCA+blood	IL-1b	HCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.544	0.00358	no	no	no	up	up	no	DM-DS
HCA+blood	IL-1b	HCA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.544	0.00358	no	no	no	up	up	no	DM-DS
iso-LCA+stool	IL-1b	iso-LCA+stool-TCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	DM-DS
iso-LCA+stool	IL-1b	iso-LCA+stool-TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	DM-DS
DCA+blood	IL-1b	DCA+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-DMG+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood+16:0/20:5-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-1b	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF-IL-17A-IL-1b"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.00358	up	up	no	up	up	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-1b	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF+IL-13+IL-1b"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.00358	up	up	no	up	up	no	DM-DS
nutriCA+blood	IL-1b	nutriCA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.726	0.00358	no	no	no	up	up	no	DM-DS
nutriCA+blood	IL-1b	nutriCA+blood+UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.726	0.00358	no	no	no	up	up	no	DM-DS
Indole-3-Acetic acid+stool	IL-1b	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00358	no	no	no	up	up	no	DM-DS
TCA+stool	IL-1b	TCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-DS
TCA+stool	IL-1b	TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-DS
HDCA+stool	IL-1b	HDCA+stool+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	DM-DS
HDCA+stool	IL-1b	HDCA+stool+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	DM-DS
Lachnospira	IL-1b	Lachnospira-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.279	0.00358	no	no	no	up	up	no	DM-DS
Lachnospira	IL-1b	Lachnospira-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.279	0.00358	no	no	no	up	up	no	DM-DS
Lachnospira	IL-1b	Lachnospira-Cytosolic DNA-sensing pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.279	0.00358	no	no	no	up	up	no	DM-DS
Lachnospira	IL-1b	Lachnospira-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.279	0.00358	no	no	no	up	up	no	DM-DS
Fusobacterium	IL-1b	Fusobacterium-18:0/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.628	0.00358	no	no	no	up	up	no	DM-DS
Fusobacterium	IL-1b	Fusobacterium+16:0-LPC+blood-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.628	0.00358	no	no	no	up	up	no	DM-DS
Fusobacterium	IL-1b	Fusobacterium-16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.628	0.00358	no	no	no	up	up	no	DM-DS
Fusobacterium	IL-1b	Fusobacterium-18:0/18:2-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.628	0.00358	no	no	no	up	up	no	DM-DS
Fusobacterium	IL-1b	Fusobacterium-18:0/18:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.628	0.00358	no	no	no	up	up	no	DM-DS
Fusobacterium	IL-1b	Fusobacterium-18:1/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.628	0.00358	no	no	no	up	up	no	DM-DS
Fusobacterium	IL-1b	Fusobacterium-18:0/18:0-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.628	0.00358	no	no	no	up	up	no	DM-DS
Fusobacterium	IL-1b	Fusobacterium-18:0/18:1-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.628	0.00358	no	no	no	up	up	no	DM-DS
GCDCA+stool	IL-1b	GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-nutriCA+stool+18:1/20:3-PC+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-nutriCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:1-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:2-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-nutriCA+stool+18:1/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-DS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:0-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-HDCA+stool+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Neuroactive ligand-receptor interaction-Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+16:0/20:4-PI+blood-Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Proteasome-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Glycolysis / Gluconeogenesis-Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Glutamatergic synapse+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	"Odoribacter-Growth hormone synthesis, secretion and action+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b"	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Ferroptosis+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Fc gamma R-mediated phagocytosis+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Proteasome-Apoptosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Glycolysis / Gluconeogenesis-Apoptosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Neuroactive ligand-receptor interaction+Apoptosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Antigen processing and presentation+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Proteasome-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Glycolysis / Gluconeogenesis-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Neuroactive ligand-receptor interaction+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Proteasome-cAMP signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Glycolysis / Gluconeogenesis-cAMP signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Proteasome-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Glycolysis / Gluconeogenesis-Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Glutamatergic synapse+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	"Odoribacter-Growth hormone synthesis, secretion and action+Chagas disease+FGF basic+IL-17A-IL-1b"	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Long-term depression+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Ferroptosis+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Proteasome-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Glycolysis / Gluconeogenesis-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	"Odoribacter-Growth hormone synthesis, secretion and action+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b"	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Longevity regulating pathway - multiple species-Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Proteasome+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Fc gamma R-mediated phagocytosis-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Morphine addiction-Hepatitis C+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Proteasome-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Glycolysis / Gluconeogenesis-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Neuroactive ligand-receptor interaction+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Pathogenic Escherichia coli infection-Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Necroptosis-Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Long-term depression-Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Ferroptosis-Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Longevity regulating pathway - multiple species+Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Endocrine resistance-Sphingolipid signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Proteasome-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Glycolysis / Gluconeogenesis-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Necroptosis-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Serotonergic synapse+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Proteasome-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Glycolysis / Gluconeogenesis-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Glutamatergic synapse+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	"Odoribacter-Growth hormone synthesis, secretion and action+Amoebiasis+FGF basic+IL-17A-IL-1b"	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Neuroactive ligand-receptor interaction+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Leishmaniasis-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Gap junction+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Legionellosis-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Long-term depression+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Ferroptosis+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Fc gamma R-mediated phagocytosis+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Proteasome-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Glycolysis / Gluconeogenesis-Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Proteasome-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Glycolysis / Gluconeogenesis-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	"Odoribacter-Growth hormone synthesis, secretion and action+Small cell lung cancer+FGF basic+IL-17A-IL-1b"	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Serotonergic synapse+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Proteasome-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Glycolysis / Gluconeogenesis-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Glutamatergic synapse+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Gap junction+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Necroptosis+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Long-term depression+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Carbon metabolism-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-Ferroptosis+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Longevity regulating pathway - multiple species-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter-HDCA+stool+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+Neuroactive ligand-receptor interaction-Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Odoribacter	IL-1b	Odoribacter+16:0/20:4-PI+blood-Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus+Roseburia+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus+Roseburia+16:0/16:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus+Roseburia-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:0/18:2-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:1/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus+Roseburia+16:0/16:1-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus+16:0/16:0-PC+blood-18:0-LPC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus+Roseburia+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus+16:0/16:0-PC+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus+Roseburia+16:0/16:1-PC+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus+16:0/16:0-PC+blood+22:0/16:0-PE+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Actinomyces	IL-1b	Actinomyces+Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.621	0.00358	no	no	no	up	up	no	DM-DS
Isobutyric acid+stool	IL-1b	Isobutyric acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.00358	no	no	no	up	up	no	DM-DS
2-hydroxyphenylacetic acid+urine	IL-1b	"2-hydroxyphenylacetic acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF+IL-13+IL-1b"	Indirect	urine_cometabolism	serum_cytokines	0.763	0.00358	no	no	no	up	up	no	DM-DS
2-hydroxyphenylacetic acid+urine	IL-1b	"2-hydroxyphenylacetic acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF-IL-17A-IL-1b"	Indirect	urine_cometabolism	serum_cytokines	0.763	0.00358	no	no	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-nutriCA+stool+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-nutriCA+stool+18:1/20:3-PC+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool+L-Phenylalanine+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-nutriCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool+L-Phenylalanine+stool-16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-nutriCA+stool+18:0/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-nutriCA+stool+18:0/18:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-nutriCA+stool+18:0/18:0-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-nutriCA+stool+18:1/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-nutriCA+stool+18:0/20:2-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-nutriCA+stool+18:0/18:1-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-DS
Caproic acid+stool	IL-1b	Caproic acid+stool-TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.882	0.00358	no	no	no	up	up	no	DM-DS
Caproic acid+stool	IL-1b	Caproic acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.882	0.00358	no	no	no	up	up	no	DM-DS
Caproic acid+stool	IL-1b	Caproic acid+stool-TCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.882	0.00358	no	no	no	up	up	no	DM-DS
Eggerthella	IL-1b	Eggerthella-Yersinia infection+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.912	0.00358	no	no	no	up	up	no	DM-DS
Eggerthella	IL-1b	Eggerthella+Phosphatidylinositol signaling system-Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.912	0.00358	no	no	no	up	up	no	DM-DS
Eggerthella	IL-1b	Eggerthella-Yersinia infection-Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.912	0.00358	no	no	no	up	up	no	DM-DS
Eggerthella	IL-1b	Eggerthella+Phosphatidylinositol signaling system+Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.912	0.00358	no	no	no	up	up	no	DM-DS
Eggerthella	IL-1b	Eggerthella-Influenza A-Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.912	0.00358	no	no	no	up	up	no	DM-DS
Eggerthella	IL-1b	Eggerthella+AMPK signaling pathway-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.912	0.00358	no	no	no	up	up	no	DM-DS
Eggerthella	IL-1b	Eggerthella+Phosphatidylinositol signaling system-Cytosolic DNA-sensing pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.912	0.00358	no	no	no	up	up	no	DM-DS
Eggerthella	IL-1b	Eggerthella+Phosphatidylinositol signaling system+Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.912	0.00358	no	no	no	up	up	no	DM-DS
Eggerthella	IL-1b	Eggerthella+Phosphatidylinositol signaling system-Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.912	0.00358	no	no	no	up	up	no	DM-DS
Eggerthella	IL-1b	Eggerthella+Phosphatidylinositol signaling system-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.912	0.00358	no	no	no	up	up	no	DM-DS
Eggerthella	IL-1b	Eggerthella+AMPK signaling pathway-Apoptosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.912	0.00358	no	no	no	up	up	no	DM-DS
Eggerthella	IL-1b	Eggerthella+Phosphatidylinositol signaling system-Apoptosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.912	0.00358	no	no	no	up	up	no	DM-DS
Eggerthella	IL-1b	Eggerthella+AMPK signaling pathway-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.912	0.00358	no	no	no	up	up	no	DM-DS
Eggerthella	IL-1b	Eggerthella+Phosphatidylinositol signaling system-B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.912	0.00358	no	no	no	up	up	no	DM-DS
Anaerotruncus	IL-1b	Anaerotruncus-Ruminococcus-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	DM-DS
Anaerotruncus	IL-1b	Anaerotruncus-Ruminococcus-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	DM-DS
Anaerostipes	IL-1b	Anaerostipes+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.568	0.00358	no	no	no	up	up	no	DM-DS
Anaerostipes	IL-1b	Anaerostipes+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.568	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-DHA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool+9-HODE+blood+AA+blood+DHA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-d18:1-14:0-SM+blood+d18:1-14:1-SM+blood-DHA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool+9-HODE+blood-d18:1-14:1-SM+blood-DHA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-L-2-Aminobutyric acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool+9-HODE+blood+AA+blood+L-2-Aminobutyric acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-L-2-Aminobutyric acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:3/16:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:3/18:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-20:3/18:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:5/18:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-d18:1-18:0-SM+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:2-PC+blood-d18:1-18:0-SM+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-EPA+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool+9-HODE+blood+AA+blood+EPA+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-22:6n3+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-d18:1-14:0-SM+blood+d18:1-20:0-SM+blood-decanoic acid C10+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood-Creatinine+blood+DMG+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood+DMG+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood-DMG+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood+16:0/20:5-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood-DL-methionine sulfoxide+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-d18:1-14:0-SM+blood-Ethanolamine+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-d18:1-14:0-SM+blood-L-Asparagine+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood+18:2-LPE+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-20:5n3+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood+18:1/18:0-PS+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood+18:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:1/20:4-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:2-PC+blood-20:1/20:4-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:1-PC+blood-20:1/20:4-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:5/18:0-PC+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-22:0/16:0-PE+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-22:6-LPC+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:2-PC+blood+18:3-LPC+blood+18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:1-PC+blood+18:3-LPC+blood+18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood+18:3-LPC+blood+18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood-18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood+18:1/18:1-PG+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood-18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool+9-HODE+blood+AA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+24:0+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-d18:1-14:0-SM+blood-L-Asparagine+blood+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood-UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool+9-HODE+blood+AA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood+24:0+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-d18:1-14:0-SM+blood-L-Asparagine+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood-UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
TUDCA+stool	IL-1b	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-DS
Isovaleric acid+stool	IL-1b	Isovaleric acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.00358	no	no	no	up	up	no	DM-DS
Paraprevotella	IL-1b	Paraprevotella-Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-DS
Paraprevotella	IL-1b	Paraprevotella+Ribosome biogenesis in eukaryotes-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-DS
¦Ø-MCA+stool	IL-1b	¦Ø-MCA+stool+CDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.919	0.00358	no	no	no	up	up	no	DM-DS
Phenylacetic acid+stool	IL-1b	Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+Pathways in cancer+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+ErbB signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+ErbB signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+Pathways in cancer+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+ErbB signaling pathway+Prostate cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+Pathways in cancer+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+ErbB signaling pathway+Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+ErbB signaling pathway+Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+Pathways in cancer+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+ErbB signaling pathway+Acute myeloid leukemia+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+Signaling pathways regulating pluripotency of stem cells-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+Colorectal cancer-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+Gastric cancer-16:1/16:1-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+ErbB signaling pathway+Chagas disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+ErbB signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+ErbB signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
Gemmiger	IL-1b	Gemmiger+ErbB signaling pathway-Estrogen signaling pathway-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-DS
GDCA+stool	IL-1b	GDCA+stool-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-DS
GDCA+stool	IL-1b	GDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-DS
Methanobrevibacter	IL-1b	Methanobrevibacter-Alcoholism+Amoebiasis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.629	0.00358	no	no	no	up	up	no	DM-DS
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	DM-DS
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	DM-DS
CDCA+stool	IL-1b	CDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.00358	no	no	no	up	up	no	DM-DS
CA+stool	IL-1b	CA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	DM-DS
CA+stool	IL-1b	CA+stool+CDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	DM-DS
HDCA+blood	IL-1b	HDCA+blood+Hypotaurine+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.483	0.00358	no	no	no	up	up	no	DM-DS
HDCA+blood	IL-1b	HDCA+blood+Hypotaurine+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.483	0.00358	no	no	no	up	up	no	DM-DS
HDCA+blood	IL-1b	HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.483	0.00358	no	no	no	up	up	no	DM-DS
HDCA+blood	IL-1b	HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.483	0.00358	no	no	no	up	up	no	DM-DS
UDCA+stool	IL-1b	UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.00358	no	no	no	up	up	no	DM-DS
UDCA+stool	IL-1b	UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.00358	no	no	no	up	up	no	DM-DS
UDCA+stool	IL-1b	UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.00358	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-1b	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.00358	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-1b	TDCA+stool-12-ketoDCA+blood-18:0/22:6-PI+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.00358	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-1b	TDCA+stool-12-ketoDCA+blood-18:0/22:6-PE+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.00358	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-1b	TDCA+stool-12-ketoDCA+blood-18:1/22:6-PE+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.00358	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-1b	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.00358	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-1b	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PE+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.00358	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-1b	TDCA+stool-12-ketoDCA+blood-16:1/18:1-PG+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.00358	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-1b	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.00358	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-1b	TDCA+stool-12-ketoDCA+blood-18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.00358	no	no	no	up	up	no	DM-DS
TDCA+stool	IL-1b	TDCA+stool-12-ketoDCA+blood-18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.00358	no	no	no	up	up	no	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	IL-1b	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	urine_cometabolism	serum_cytokines	0.973	0.00358	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-1b	Desulfovibrio+Human T-cell leukemia virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.27	0.00358	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-1b	Desulfovibrio+Human cytomegalovirus infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.27	0.00358	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-1b	Desulfovibrio+Human immunodeficiency virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.27	0.00358	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-1b	Desulfovibrio+Antigen processing and presentation+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.27	0.00358	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-1b	Desulfovibrio+Herpes simplex virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.27	0.00358	no	no	no	up	up	no	DM-DS
Desulfovibrio	IL-1b	Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.27	0.00358	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-1b	nutriCA+stool+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.00358	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-1b	nutriCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.00358	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-1b	nutriCA+stool+18:0/18:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.00358	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-1b	nutriCA+stool+18:0/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.00358	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-1b	nutriCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.00358	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-1b	nutriCA+stool+18:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.00358	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-1b	nutriCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.00358	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-1b	nutriCA+stool+18:0/18:1-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.00358	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-1b	nutriCA+stool+18:0/18:0-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.00358	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-1b	nutriCA+stool+18:1/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.00358	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-1b	nutriCA+stool+18:0/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.00358	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-1b	nutriCA+stool+18:0/20:2-PC+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.00358	no	no	no	up	up	no	DM-DS
nutriCA+stool	IL-1b	nutriCA+stool+18:1/20:3-PC+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.00358	no	no	no	up	up	no	DM-DS
Bilophila	IL-1b	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.528	0.00358	no	no	no	up	up	no	DM-DS
Bilophila	IL-1b	Bilophila+Desulfovibrio+Human cytomegalovirus infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.528	0.00358	no	no	no	up	up	no	DM-DS
Bilophila	IL-1b	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.528	0.00358	no	no	no	up	up	no	DM-DS
Bilophila	IL-1b	Bilophila+Desulfovibrio+Antigen processing and presentation+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.528	0.00358	no	no	no	up	up	no	DM-DS
Bilophila	IL-1b	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.528	0.00358	no	no	no	up	up	no	DM-DS
Bilophila	IL-1b	Bilophila+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.528	0.00358	no	no	no	up	up	no	DM-DS
GDCA+blood	IL-1b	GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.632	0.00358	no	no	no	up	up	no	DM-DS
GDCA+blood	IL-1b	GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.632	0.00358	no	no	no	up	up	no	DM-DS
GDCA+blood	IL-1b	GDCA+blood+Hypotaurine+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.632	0.00358	no	no	no	up	up	no	DM-DS
GDCA+blood	IL-1b	GDCA+blood+Hypotaurine+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.632	0.00358	no	no	no	up	up	no	DM-DS
P-hydroxyhippuric acid+urine	IL-1b	P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	urine_cometabolism	serum_cytokines	0.436	0.00358	no	no	no	up	up	no	DM-DS
P-hydroxyhippuric acid+urine	IL-1b	P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	urine_cometabolism	serum_cytokines	0.436	0.00358	no	no	no	up	up	no	DM-DS
acetic acid C2+blood	IL-1b	acetic acid C2+blood+d18:1-20:1-SM+blood-decanoic acid C10+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.00358	up	dn	no	up	up	no	DM-DS
isovaleric acid iso-C5+blood	IL-1b	isovaleric acid iso-C5+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.117	0.00358	no	no	no	up	up	no	DM-DS
Clostridium	IL-1b	Clostridium-Eotaxin-GM-CSF+IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-DS
Clostridium	IL-1b	Clostridium-Small cell lung cancer+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-DS
Clostridium	IL-1b	Clostridium-Relaxin signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-DS
Clostridium	IL-1b	Clostridium-cAMP signaling pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-DS
Clostridium	IL-1b	Clostridium-Eotaxin-GM-CSF-IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-DS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-DS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-DS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-18:0/18:1-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-16:1/18:1-PG+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-18:0/18:1-PE+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-18:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-18:1/22:6-PE+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-18:0/22:6-PI+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-16:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	DM-DS
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-18:0/22:6-PE+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	DM-DS
Butyricicoccus	IL-1b	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF+IL-13+IL-1b"	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	DM-DS
Butyricicoccus	IL-1b	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A-IL-1b"	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	DM-DS
Butyricicoccus	IL-1b	Butyricicoccus-18:2/20:4-PC+blood-DMG+blood-n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	DM-DS
Butyricicoccus	IL-1b	Butyricicoccus-18:2/20:4-PC+blood+20:4n6+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	DM-DS
Butyricicoccus	IL-1b	Butyricicoccus-18:2/20:4-PC+blood+EPA+blood+n3+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	DM-DS
Butyricicoccus	IL-1b	"Butyricicoccus+12,13-EPOME+blood-18:0/20:4-PI+blood+n3+blood-FGF basic+IL-17A-IL-1b"	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	DM-DS
Butyricicoccus	IL-1b	Butyricicoccus-18:2/20:4-PC+blood+20:4n6+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	DM-DS
Butyricicoccus	IL-1b	Butyricicoccus-18:2/20:4-PC+blood+20:3/16:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	DM-DS
Butyricicoccus	IL-1b	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b"	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	DM-DS
Butyricicoccus	IL-1b	"Butyricicoccus+12,13-EPOME+blood+18:0/18:1-PE+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b"	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	DM-DS
Blautia	GM-CSF	Blautia+Dorea-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	1.36E-05	0.0124	up	dn	dn	up	no	no	DM-DS
Parabacteroides	GM-CSF	Parabacteroides-16:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	4.19E-05	0.0124	no	up	up	up	no	no	DM-DS
Dorea	GM-CSF	Dorea-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.00362	0.0124	up	no	dn	up	no	no	DM-DS
Faecalibacterium	GM-CSF	Faecalibacterium-Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0039	0.0124	no	dn	dn	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Transcriptional misregulation in cancer-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+RNA transport+UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+Oocyte meiosis+UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Prolactin signaling pathway-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+Apelin signaling pathway+UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Phospholipase D signaling pathway-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Amoebiasis-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Chagas disease-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Acute myeloid leukemia-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+Glycolysis / Gluconeogenesis+UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+Long-term potentiation+UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Prolactin signaling pathway-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Relaxin signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+Oocyte meiosis+Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-cAMP signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Prolactin signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Amoebiasis-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Chagas disease-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Chronic myeloid leukemia-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Acute myeloid leukemia-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+Longevity regulating pathway - multiple species+Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+Long-term potentiation+Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Long-term depression-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Pathways in cancer-16:0/20:4-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+Parabacteroides-16:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Amoebiasis+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+16:1/16:1-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+16:0/22:6-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+20:3/18:0-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+18:0/20:4-PC+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+Apelin signaling pathway-IL-17 signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Phospholipase D signaling pathway+IL-17 signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Pathways in cancer+L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+16:0/20:5-PC+blood-L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+Glycolysis / Gluconeogenesis-p53 signaling pathway+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Transcriptional misregulation in cancer-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Pathways in cancer-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Chronic myeloid leukemia-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Choline metabolism in cancer-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-MicroRNAs in cancer-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	"Bacteroides-Growth hormone synthesis, secretion and action-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF"	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+Glycolysis / Gluconeogenesis+Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-16:1/18:2-PG+blood+18:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+Long-term potentiation-18:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Long-term depression+18:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+Glycolysis / Gluconeogenesis+Leukocyte transendothelial migration-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+Glycolysis / Gluconeogenesis+Platelet activation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+RNA transport-Neutrophil extracellular trap formation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+Apelin signaling pathway-Neutrophil extracellular trap formation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides-Phospholipase D signaling pathway+Neutrophil extracellular trap formation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+RNA transport+Measles+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+Legionellosis+Measles+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Bacteroides	GM-CSF	Bacteroides+Leishmaniasis+Measles+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-DS
Propionic acid+stool	GM-CSF	Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.0436	0.0124	dn	no	up	up	no	no	DM-DS
[Ruminococcus]	GM-CSF	[Ruminococcus]-Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0679	0.0124	no	no	dn	up	no	no	DM-DS
[Ruminococcus]	GM-CSF	[Ruminococcus]+16:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0679	0.0124	no	no	dn	up	no	no	DM-DS
GUDCA+blood	GM-CSF	GUDCA+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0124	no	no	dn	up	no	no	DM-DS
UDCA+blood	GM-CSF	UDCA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.0939	0.0124	no	no	dn	up	no	no	DM-DS
Acetic acid+stool	GM-CSF	Acetic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.0656	0.0124	dn	no	no	up	no	no	DM-DS
Alistipes	GM-CSF	Alistipes-Platelet activation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0114	0.0124	no	up	no	up	no	no	DM-DS
Alistipes	GM-CSF	Alistipes-Oxytocin signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0114	0.0124	no	up	no	up	no	no	DM-DS
Alistipes	GM-CSF	Alistipes-Rap1 signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0114	0.0124	no	up	no	up	no	no	DM-DS
Butyricimonas	GM-CSF	Butyricimonas-L-Asparagine+blood+L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.17	0.0124	no	no	no	up	no	no	DM-DS
Butyricimonas	GM-CSF	Butyricimonas-iso-DCA+blood+L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.17	0.0124	no	no	no	up	no	no	DM-DS
Butyricimonas	GM-CSF	Butyricimonas-Butyric acid+stool+L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.17	0.0124	no	no	no	up	no	no	DM-DS
Butyricimonas	GM-CSF	Butyricimonas-Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.17	0.0124	no	no	no	up	no	no	DM-DS
Collinsella	GM-CSF	Collinsella+Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-DS
Collinsella	GM-CSF	Collinsella-Renin secretion+UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-DS
Collinsella	GM-CSF	Collinsella-Inflammatory mediator regulation of TRP channels+UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-DS
Collinsella	GM-CSF	Collinsella-Endocrine and other factor-regulated calcium reabsorption+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-DS
Collinsella	GM-CSF	Collinsella-GnRH signaling pathway-Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-DS
Collinsella	GM-CSF	Collinsella-Renin secretion-Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-DS
Collinsella	GM-CSF	Collinsella-Endocrine and other factor-regulated calcium reabsorption-Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-DS
Collinsella	GM-CSF	Collinsella-Inflammatory mediator regulation of TRP channels-Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-DS
Collinsella	GM-CSF	Collinsella-GnRH signaling pathway+HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-DS
Collinsella	GM-CSF	Collinsella-Endocrine and other factor-regulated calcium reabsorption+HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Osteoclast differentiation+Neutrophil extracellular trap formation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Cellular senescence+Neutrophil extracellular trap formation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Apoptosis+Neutrophil extracellular trap formation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Osteoclast differentiation+IL-17 signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Cellular senescence+IL-17 signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Apoptosis+IL-17 signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+NF-kappa B signaling pathway+IL-17 signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Toll-like receptor signaling pathway+IL-17 signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+RIG-I-like receptor signaling pathway+IL-17 signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+C-type lectin receptor signaling pathway+IL-17 signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Dopaminergic synapse-Measles+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Hepatitis C+Measles+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Circadian entrainment-Measles+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Th17 cell differentiation+Measles+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Apoptosis+18:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Viral carcinogenesis-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Glucagon signaling pathway+HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Osteoclast differentiation-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Dopaminergic synapse+HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Cellular senescence-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Human papillomavirus infection-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Apoptosis-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Amphetamine addiction+HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-GnRH signaling pathway+HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Aldosterone synthesis and secretion+HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Fc epsilon RI signaling pathway-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Prolactin signaling pathway-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Glucagon signaling pathway+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Aldosterone synthesis and secretion+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Viral carcinogenesis-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Acute myeloid leukemia-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Cellular senescence-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Human papillomavirus infection-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Apoptosis-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Neurotrophin signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Chronic myeloid leukemia-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Toll-like receptor signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Fc epsilon RI signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Prostate cancer-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+C-type lectin receptor signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Prolactin signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+TNF signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+B cell receptor signaling pathway-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+NF-kappa B signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Insulin resistance-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Circadian entrainment+Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Chronic myeloid leukemia-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+RIG-I-like receptor signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Prostate cancer-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+NF-kappa B signaling pathway-Oxytocin signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Circadian entrainment+Oxytocin signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+RIG-I-like receptor signaling pathway-Oxytocin signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+TNF signaling pathway-Oxytocin signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+NF-kappa B signaling pathway-Platelet activation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Viral carcinogenesis+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Glucagon signaling pathway-Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Osteoclast differentiation+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Inflammatory mediator regulation of TRP channels-Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Cellular senescence+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Human papillomavirus infection+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Apoptosis+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Amphetamine addiction-Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Toll-like receptor signaling pathway+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-GnRH signaling pathway-Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Aldosterone synthesis and secretion-Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Fc epsilon RI signaling pathway+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+C-type lectin receptor signaling pathway+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+B cell receptor signaling pathway+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Glucagon signaling pathway+UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Osteoclast differentiation-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Inflammatory mediator regulation of TRP channels+UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Acute myeloid leukemia-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Apoptosis-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+NF-kappa B signaling pathway-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Amphetamine addiction+UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Toll-like receptor signaling pathway-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+RIG-I-like receptor signaling pathway-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina-Aldosterone synthesis and secretion+UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Fc epsilon RI signaling pathway-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+C-type lectin receptor signaling pathway-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+Prolactin signaling pathway-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Sarcina	GM-CSF	Sarcina+B cell receptor signaling pathway-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
Methanosphaera	GM-CSF	Methanosphaera-Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0703	0.0124	no	no	no	up	no	no	DM-DS
iso-DCA+stool	GM-CSF	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.155	0.0124	no	no	no	up	no	no	DM-DS
LCA+stool	GM-CSF	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.314	0.0124	no	no	no	up	no	no	DM-DS
Akkermansia	GM-CSF	Akkermansia+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-DS
Bifidobacterium	GM-CSF	Bifidobacterium+Leukocyte transendothelial migration-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.105	0.0124	no	dn	no	up	no	no	DM-DS
Ruminococcus	GM-CSF	"Ruminococcus-18:2n6c+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF"	Indirect	Genus	serum_cytokines	0.335	0.0124	no	no	no	up	no	no	DM-DS
Ruminococcus	GM-CSF	Ruminococcus-Alcoholism+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.335	0.0124	no	no	no	up	no	no	DM-DS
Ruminococcus	GM-CSF	Ruminococcus-Alcoholism-Measles+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.335	0.0124	no	no	no	up	no	no	DM-DS
Ruminococcus	GM-CSF	Ruminococcus-Serotonergic synapse-Measles+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.335	0.0124	no	no	no	up	no	no	DM-DS
Ruminococcus	GM-CSF	Ruminococcus-20:4-LPC+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.335	0.0124	no	no	no	up	no	no	DM-DS
Ruminococcus	GM-CSF	Ruminococcus-EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.335	0.0124	no	no	no	up	no	no	DM-DS
Ruminococcus	GM-CSF	Ruminococcus+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.335	0.0124	no	no	no	up	no	no	DM-DS
Ruminococcus	GM-CSF	Ruminococcus-18:3n3+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.335	0.0124	no	no	no	up	no	no	DM-DS
Ruminococcus	GM-CSF	Ruminococcus+18:0/18:0-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.335	0.0124	no	no	no	up	no	no	DM-DS
GCDCA+blood	GM-CSF	GCDCA+blood+GUDCA+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.31	0.0124	no	no	no	up	no	no	DM-DS
GCDCA+blood	GM-CSF	GCDCA+blood+HCA+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.31	0.0124	no	no	no	up	no	no	DM-DS
ACA+blood	GM-CSF	ACA+blood+EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.338	0.0124	no	no	no	up	no	no	DM-DS
DCA+stool	GM-CSF	DCA+stool+HDCA+stool+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.195	0.0124	no	no	no	up	no	no	DM-DS
Butyric acid+stool	GM-CSF	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.102	0.0124	dn	no	no	up	no	no	DM-DS
Butyric acid+stool	GM-CSF	Butyric acid+stool+L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.102	0.0124	dn	no	no	up	no	no	DM-DS
4-hydroxybenzoic acid+stool	GM-CSF	4-hydroxybenzoic acid+stool-DCA+stool+HDCA+stool+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.0124	no	dn	no	up	no	no	DM-DS
Turicibacter	GM-CSF	Turicibacter+Desulfovibrio+Antigen processing and presentation+Leukocyte transendothelial migration-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.269	0.0124	no	no	no	up	no	no	DM-DS
Turicibacter	GM-CSF	Turicibacter+Desulfovibrio+Antigen processing and presentation-Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.269	0.0124	no	no	no	up	no	no	DM-DS
Turicibacter	GM-CSF	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.269	0.0124	no	no	no	up	no	no	DM-DS
Turicibacter	GM-CSF	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.269	0.0124	no	no	no	up	no	no	DM-DS
Turicibacter	GM-CSF	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.269	0.0124	no	no	no	up	no	no	DM-DS
Turicibacter	GM-CSF	Turicibacter+Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.269	0.0124	no	no	no	up	no	no	DM-DS
Turicibacter	GM-CSF	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.269	0.0124	no	no	no	up	no	no	DM-DS
Turicibacter	GM-CSF	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.269	0.0124	no	no	no	up	no	no	DM-DS
Turicibacter	GM-CSF	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.269	0.0124	no	no	no	up	no	no	DM-DS
Turicibacter	GM-CSF	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.269	0.0124	no	no	no	up	no	no	DM-DS
Turicibacter	GM-CSF	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.269	0.0124	no	no	no	up	no	no	DM-DS
Turicibacter	GM-CSF	Turicibacter+Desulfovibrio+Antigen processing and presentation-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.269	0.0124	no	no	no	up	no	no	DM-DS
Turicibacter	GM-CSF	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.269	0.0124	no	no	no	up	no	no	DM-DS
GCA+blood	GM-CSF	GCA+blood+HCA+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.16	0.0124	no	no	no	up	no	no	DM-DS
ACA+stool	GM-CSF	ACA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.417	0.0124	no	no	no	up	no	no	DM-DS
CDCA+blood	GM-CSF	CDCA+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.506	0.0124	no	no	no	up	no	no	DM-DS
capric acid C6+blood	GM-CSF	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.433	0.0124	no	no	no	up	no	no	DM-DS
Prevotella	GM-CSF	Prevotella-Measles+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.287	0.0124	no	no	no	up	no	no	DM-DS
iso-DCA+blood	GM-CSF	iso-DCA+blood+L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.38	0.0124	no	no	no	up	no	no	DM-DS
HCA+stool	GM-CSF	HCA+stool-HDCA+stool+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.155	0.0124	no	no	no	up	no	no	DM-DS
Roseburia	GM-CSF	Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.495	0.0124	no	no	no	up	no	no	DM-DS
12-ketoDCA+stool	GM-CSF	12-ketoDCA+stool+HDCA+stool+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.505	0.0124	no	no	no	up	no	no	DM-DS
GLCA+blood	GM-CSF	GLCA+blood-SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.319	0.0124	no	no	no	up	no	no	DM-DS
L-Tryptophan+stool	GM-CSF	L-Tryptophan+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0124	no	no	no	up	no	no	DM-DS
CA+blood	GM-CSF	CA+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.606	0.0124	no	no	no	up	no	no	DM-DS
GUDCA+stool	GM-CSF	GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0085	0.0124	no	dn	no	up	no	no	DM-DS
L-Phenylalanine+stool	GM-CSF	L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool-GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool-HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool-Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool+GCDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool+GDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool+DPA+blood-nutriCA+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool+GCDCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool-Isovaleric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool-Isobutyric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool+GCDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool+UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool+GDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool-iso-LCA+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool+GCDCA+stool+16:0/16:1-PC+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool-12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool+GCDCA+stool+16:1/18:2-PG+blood+18:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	GCA+stool+GCDCA+stool+16:0/18:2-PC+blood-16:0/20:4-PI+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
GCA+stool	GM-CSF	"GCA+stool+GDCA+stool+L-Lysine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF"	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-DS
Coprococcus	GM-CSF	Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.612	0.0124	no	no	no	up	no	no	DM-DS
Coprococcus	GM-CSF	Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.612	0.0124	no	no	no	up	no	no	DM-DS
Coprococcus	GM-CSF	Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.612	0.0124	no	no	no	up	no	no	DM-DS
Oscillospira	GM-CSF	Oscillospira+Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.62	0.0124	no	no	no	up	no	no	DM-DS
Oscillospira	GM-CSF	Oscillospira-Rap1 signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.62	0.0124	no	no	no	up	no	no	DM-DS
Oscillospira	GM-CSF	Oscillospira+Spliceosome+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.62	0.0124	no	no	no	up	no	no	DM-DS
Oscillospira	GM-CSF	Oscillospira-Platelet activation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.62	0.0124	no	no	no	up	no	no	DM-DS
HCA+blood	GM-CSF	HCA+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.544	0.0124	no	no	no	up	no	no	DM-DS
iso-LCA+stool	GM-CSF	iso-LCA+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.72	0.0124	no	no	no	up	no	no	DM-DS
DCA+blood	GM-CSF	DCA+blood+nutriCA+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.122	0.0124	no	no	no	up	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	GM-CSF	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0124	no	no	no	up	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	GM-CSF	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.0124	up	up	no	up	no	no	DM-DS
nutriCA+blood	GM-CSF	nutriCA+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.726	0.0124	no	no	no	up	no	no	DM-DS
Indole-3-Acetic acid+stool	GM-CSF	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0124	no	no	no	up	no	no	DM-DS
TCA+stool	GM-CSF	TCA+stool+16:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-DS
HDCA+stool	GM-CSF	HDCA+stool+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.176	0.0124	no	no	no	up	no	no	DM-DS
Lachnospira	GM-CSF	Lachnospira-p53 signaling pathway+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.279	0.0124	no	no	no	up	no	no	DM-DS
Lachnospira	GM-CSF	Lachnospira+Platelet activation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.279	0.0124	no	no	no	up	no	no	DM-DS
Lachnospira	GM-CSF	Lachnospira-Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.279	0.0124	no	no	no	up	no	no	DM-DS
Lachnospira	GM-CSF	Lachnospira+Rap1 signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.279	0.0124	no	no	no	up	no	no	DM-DS
Lachnospira	GM-CSF	Lachnospira-Spliceosome+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.279	0.0124	no	no	no	up	no	no	DM-DS
Lachnospira	GM-CSF	Lachnospira+Leukocyte transendothelial migration-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.279	0.0124	no	no	no	up	no	no	DM-DS
Lachnospira	GM-CSF	Lachnospira+Oxytocin signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.279	0.0124	no	no	no	up	no	no	DM-DS
Lachnospira	GM-CSF	Lachnospira+Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.279	0.0124	no	no	no	up	no	no	DM-DS
Fusobacterium	GM-CSF	Fusobacterium-Intestinal immune network for IgA production-L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.628	0.0124	no	no	no	up	no	no	DM-DS
Fusobacterium	GM-CSF	Fusobacterium-Intestinal immune network for IgA production-Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.628	0.0124	no	no	no	up	no	no	DM-DS
Fusobacterium	GM-CSF	Fusobacterium-Intestinal immune network for IgA production-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.628	0.0124	no	no	no	up	no	no	DM-DS
Fusobacterium	GM-CSF	Fusobacterium-18:0/18:0-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.628	0.0124	no	no	no	up	no	no	DM-DS
Fusobacterium	GM-CSF	Fusobacterium-16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.628	0.0124	no	no	no	up	no	no	DM-DS
Fusobacterium	GM-CSF	Fusobacterium-18:0/18:1-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.628	0.0124	no	no	no	up	no	no	DM-DS
Fusobacterium	GM-CSF	Fusobacterium-GUDCA+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.628	0.0124	no	no	no	up	no	no	DM-DS
Fusobacterium	GM-CSF	Fusobacterium-16:0/18:2-PC+blood-16:0/20:4-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.628	0.0124	no	no	no	up	no	no	DM-DS
GCDCA+stool	GM-CSF	GCDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0124	no	dn	no	up	no	no	DM-DS
GCDCA+stool	GM-CSF	GCDCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0124	no	dn	no	up	no	no	DM-DS
GCDCA+stool	GM-CSF	GCDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0124	no	dn	no	up	no	no	DM-DS
GCDCA+stool	GM-CSF	GCDCA+stool+16:0/18:2-PC+blood-16:0/20:4-PI+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0124	no	dn	no	up	no	no	DM-DS
GCDCA+stool	GM-CSF	GCDCA+stool+16:0/16:1-PC+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0124	no	dn	no	up	no	no	DM-DS
GCDCA+stool	GM-CSF	GCDCA+stool+16:1/18:2-PG+blood+18:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0124	no	dn	no	up	no	no	DM-DS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool+Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-DS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool+Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-DS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-DS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:1-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-DS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-DS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool-nutriCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-DS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:0-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-DS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool-nutriCA+stool-13-HODE+blood-16:0/20:4-PI+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-DS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/22:6-PA+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-DS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-DS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool-nutriCA+stool-AA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-DS
Odoribacter	GM-CSF	Odoribacter-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.798	0.0124	no	no	no	up	no	no	DM-DS
Odoribacter	GM-CSF	Odoribacter+Neuroactive ligand-receptor interaction-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.798	0.0124	no	no	no	up	no	no	DM-DS
Odoribacter	GM-CSF	Odoribacter+16:0/20:4-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.798	0.0124	no	no	no	up	no	no	DM-DS
Actinomyces	GM-CSF	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.621	0.0124	no	no	no	up	no	no	DM-DS
Actinomyces	GM-CSF	Actinomyces+Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.621	0.0124	no	no	no	up	no	no	DM-DS
Actinomyces	GM-CSF	Actinomyces+Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.621	0.0124	no	no	no	up	no	no	DM-DS
Isobutyric acid+stool	GM-CSF	Isobutyric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.408	0.0124	no	no	no	up	no	no	DM-DS
Isobutyric acid+stool	GM-CSF	Isobutyric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.408	0.0124	no	no	no	up	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	GM-CSF	"2-hydroxyphenylacetic acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF"	Indirect	urine_cometabolism	serum_cytokines	0.763	0.0124	no	no	no	up	no	no	DM-DS
Kynurenic acid+stool	GM-CSF	Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0124	dn	dn	no	up	no	no	DM-DS
Kynurenic acid+stool	GM-CSF	Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0124	dn	dn	no	up	no	no	DM-DS
Caproic acid+stool	GM-CSF	Caproic acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.882	0.0124	no	no	no	up	no	no	DM-DS
Caproic acid+stool	GM-CSF	Caproic acid+stool-TCA+stool+16:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.882	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella+AMPK signaling pathway-Neutrophil extracellular trap formation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella+Phosphatidylinositol signaling system-Neutrophil extracellular trap formation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella+AMPK signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella-Yersinia infection+Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella-Influenza A+Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella-Yersinia infection-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella+Phosphatidylinositol signaling system+Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella-Influenza A-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella-Yersinia infection-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella-Influenza A-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella-Yersinia infection-UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella+Phosphatidylinositol signaling system+Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella+AMPK signaling pathway-IL-17 signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella+Phosphatidylinositol signaling system-IL-17 signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella+AMPK signaling pathway+L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella+Phosphatidylinositol signaling system-Lysosome-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella+Phosphatidylinositol signaling system+p53 signaling pathway+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella+AMPK signaling pathway-Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella-Yersinia infection+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella+Phosphatidylinositol signaling system-Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella-Influenza A+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella-Yersinia infection+18:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Eggerthella	GM-CSF	Eggerthella+Phosphatidylinositol signaling system-18:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.912	0.0124	no	no	no	up	no	no	DM-DS
Anaerotruncus	GM-CSF	"Anaerotruncus-Ruminococcus-18:2n6c+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF"	Indirect	Genus	serum_cytokines	0.904	0.0124	no	no	no	up	no	no	DM-DS
Anaerotruncus	GM-CSF	Anaerotruncus-Ruminococcus-Alcoholism+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.904	0.0124	no	no	no	up	no	no	DM-DS
Anaerotruncus	GM-CSF	Anaerotruncus-Ruminococcus-Alcoholism-Measles+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.904	0.0124	no	no	no	up	no	no	DM-DS
Anaerotruncus	GM-CSF	Anaerotruncus-Ruminococcus-Serotonergic synapse-Measles+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.904	0.0124	no	no	no	up	no	no	DM-DS
Anaerotruncus	GM-CSF	Anaerotruncus-Ruminococcus-20:4-LPC+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.904	0.0124	no	no	no	up	no	no	DM-DS
Anaerotruncus	GM-CSF	Anaerotruncus-Ruminococcus-EPA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.904	0.0124	no	no	no	up	no	no	DM-DS
Anaerotruncus	GM-CSF	Anaerotruncus-Ruminococcus+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.904	0.0124	no	no	no	up	no	no	DM-DS
Anaerotruncus	GM-CSF	Anaerotruncus-Ruminococcus-18:3n3+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.904	0.0124	no	no	no	up	no	no	DM-DS
Anaerotruncus	GM-CSF	Anaerotruncus-Ruminococcus+18:0/18:0-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.904	0.0124	no	no	no	up	no	no	DM-DS
Anaerostipes	GM-CSF	Anaerostipes+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.568	0.0124	no	no	no	up	no	no	DM-DS
TUDCA+stool	GM-CSF	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.241	0.0124	no	no	no	up	no	no	DM-DS
TUDCA+stool	GM-CSF	TUDCA+stool+9-HODE+blood+AA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.241	0.0124	no	no	no	up	no	no	DM-DS
TUDCA+stool	GM-CSF	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.241	0.0124	no	no	no	up	no	no	DM-DS
TUDCA+stool	GM-CSF	TUDCA+stool-14:0/18:2-PC+blood+24:0+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.241	0.0124	no	no	no	up	no	no	DM-DS
TUDCA+stool	GM-CSF	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.241	0.0124	no	no	no	up	no	no	DM-DS
TUDCA+stool	GM-CSF	TUDCA+stool-d18:1-14:0-SM+blood-L-Asparagine+blood+L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.241	0.0124	no	no	no	up	no	no	DM-DS
TUDCA+stool	GM-CSF	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.241	0.0124	no	no	no	up	no	no	DM-DS
TUDCA+stool	GM-CSF	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.241	0.0124	no	no	no	up	no	no	DM-DS
Isovaleric acid+stool	GM-CSF	Isovaleric acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.343	0.0124	no	no	no	up	no	no	DM-DS
Isovaleric acid+stool	GM-CSF	Isovaleric acid+stool+Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.343	0.0124	no	no	no	up	no	no	DM-DS
Paraprevotella	GM-CSF	Paraprevotella-IL-17 signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-DS
¦Ø-MCA+stool	GM-CSF	¦Ø-MCA+stool-L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.919	0.0124	no	no	no	up	no	no	DM-DS
¦Ø-MCA+stool	GM-CSF	¦Ø-MCA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.919	0.0124	no	no	no	up	no	no	DM-DS
Phenylacetic acid+stool	GM-CSF	Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+PI3K-Akt signaling pathway+Measles+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	"Gemmiger-12,13-EPOME+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF"	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Platelet activation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+ErbB signaling pathway-Platelet activation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+ErbB signaling pathway+p53 signaling pathway+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+ErbB signaling pathway+Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+Pathways in cancer-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+ErbB signaling pathway-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+Gastric cancer-Fluid shear stress and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+Gastric cancer-Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+24:0+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+Pathways in cancer-16:0/20:4-PI+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+Pathways in cancer+L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Leukocyte transendothelial migration-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Neutrophil extracellular trap formation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Oxytocin signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
Gemmiger	GM-CSF	Gemmiger+ErbB signaling pathway-Oxytocin signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-DS
GDCA+stool	GM-CSF	GDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-DS
GDCA+stool	GM-CSF	GDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-DS
GDCA+stool	GM-CSF	"GDCA+stool+L-Lysine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF"	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-DS
Methanobrevibacter	GM-CSF	Methanobrevibacter-Alcoholism-Measles+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.629	0.0124	no	no	no	up	no	no	DM-DS
Methanobrevibacter	GM-CSF	Methanobrevibacter-Alcoholism+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.629	0.0124	no	no	no	up	no	no	DM-DS
L-Tyrosine+stool	GM-CSF	L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0124	no	no	no	up	no	no	DM-DS
CDCA+stool	GM-CSF	CDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.663	0.0124	no	no	no	up	no	no	DM-DS
CDCA+stool	GM-CSF	CDCA+stool-Phenylacetic acid+stool-UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.663	0.0124	no	no	no	up	no	no	DM-DS
CA+stool	GM-CSF	CA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.827	0.0124	no	no	no	up	no	no	DM-DS
HDCA+blood	GM-CSF	HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.483	0.0124	no	no	no	up	no	no	DM-DS
UDCA+stool	GM-CSF	UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.266	0.0124	no	no	no	up	no	no	DM-DS
TDCA+stool	GM-CSF	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.963	0.0124	no	no	no	up	no	no	DM-DS
TDCA+stool	GM-CSF	TDCA+stool-12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.963	0.0124	no	no	no	up	no	no	DM-DS
TDCA+stool	GM-CSF	TDCA+stool-12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.963	0.0124	no	no	no	up	no	no	DM-DS
TDCA+stool	GM-CSF	TDCA+stool-12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.963	0.0124	no	no	no	up	no	no	DM-DS
TDCA+stool	GM-CSF	TDCA+stool-12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.963	0.0124	no	no	no	up	no	no	DM-DS
TDCA+stool	GM-CSF	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.963	0.0124	no	no	no	up	no	no	DM-DS
TDCA+stool	GM-CSF	TDCA+stool-HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.963	0.0124	no	no	no	up	no	no	DM-DS
TDCA+stool	GM-CSF	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.963	0.0124	no	no	no	up	no	no	DM-DS
Desulfovibrio	GM-CSF	Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.27	0.0124	no	no	no	up	no	no	DM-DS
Desulfovibrio	GM-CSF	Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.27	0.0124	no	no	no	up	no	no	DM-DS
Desulfovibrio	GM-CSF	Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.27	0.0124	no	no	no	up	no	no	DM-DS
Desulfovibrio	GM-CSF	Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.27	0.0124	no	no	no	up	no	no	DM-DS
Desulfovibrio	GM-CSF	Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.27	0.0124	no	no	no	up	no	no	DM-DS
Desulfovibrio	GM-CSF	Desulfovibrio+Antigen processing and presentation-Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.27	0.0124	no	no	no	up	no	no	DM-DS
Desulfovibrio	GM-CSF	Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.27	0.0124	no	no	no	up	no	no	DM-DS
Desulfovibrio	GM-CSF	Desulfovibrio+Antigen processing and presentation+Leukocyte transendothelial migration-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.27	0.0124	no	no	no	up	no	no	DM-DS
Desulfovibrio	GM-CSF	Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.27	0.0124	no	no	no	up	no	no	DM-DS
Desulfovibrio	GM-CSF	Desulfovibrio+Human cytomegalovirus infection-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.27	0.0124	no	no	no	up	no	no	DM-DS
Desulfovibrio	GM-CSF	Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.27	0.0124	no	no	no	up	no	no	DM-DS
Desulfovibrio	GM-CSF	Desulfovibrio+Antigen processing and presentation-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.27	0.0124	no	no	no	up	no	no	DM-DS
Desulfovibrio	GM-CSF	Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.27	0.0124	no	no	no	up	no	no	DM-DS
nutriCA+stool	GM-CSF	nutriCA+stool+18:0/22:6-PA+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.481	0.0124	no	no	no	up	no	no	DM-DS
nutriCA+stool	GM-CSF	nutriCA+stool+18:0/18:1-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.481	0.0124	no	no	no	up	no	no	DM-DS
nutriCA+stool	GM-CSF	nutriCA+stool+18:0/18:0-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.481	0.0124	no	no	no	up	no	no	DM-DS
nutriCA+stool	GM-CSF	nutriCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.481	0.0124	no	no	no	up	no	no	DM-DS
nutriCA+stool	GM-CSF	nutriCA+stool-13-HODE+blood-16:0/20:4-PI+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.481	0.0124	no	no	no	up	no	no	DM-DS
nutriCA+stool	GM-CSF	nutriCA+stool-AA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.481	0.0124	no	no	no	up	no	no	DM-DS
nutriCA+stool	GM-CSF	nutriCA+stool+18:0/20:2-PC+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.481	0.0124	no	no	no	up	no	no	DM-DS
Bilophila	GM-CSF	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.528	0.0124	no	no	no	up	no	no	DM-DS
Bilophila	GM-CSF	Bilophila+Desulfovibrio+Human cytomegalovirus infection+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.528	0.0124	no	no	no	up	no	no	DM-DS
Bilophila	GM-CSF	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.528	0.0124	no	no	no	up	no	no	DM-DS
Bilophila	GM-CSF	Bilophila+Desulfovibrio+Antigen processing and presentation+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.528	0.0124	no	no	no	up	no	no	DM-DS
Bilophila	GM-CSF	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.528	0.0124	no	no	no	up	no	no	DM-DS
Bilophila	GM-CSF	Bilophila+Desulfovibrio+Antigen processing and presentation-Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.528	0.0124	no	no	no	up	no	no	DM-DS
Bilophila	GM-CSF	Bilophila+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.528	0.0124	no	no	no	up	no	no	DM-DS
Bilophila	GM-CSF	Bilophila+Desulfovibrio+Antigen processing and presentation+Leukocyte transendothelial migration-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.528	0.0124	no	no	no	up	no	no	DM-DS
Bilophila	GM-CSF	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.528	0.0124	no	no	no	up	no	no	DM-DS
Bilophila	GM-CSF	Bilophila+Desulfovibrio+Human cytomegalovirus infection-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.528	0.0124	no	no	no	up	no	no	DM-DS
Bilophila	GM-CSF	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.528	0.0124	no	no	no	up	no	no	DM-DS
Bilophila	GM-CSF	Bilophila+Desulfovibrio+Antigen processing and presentation-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.528	0.0124	no	no	no	up	no	no	DM-DS
Bilophila	GM-CSF	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection-HDCA+stool+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.528	0.0124	no	no	no	up	no	no	DM-DS
GDCA+blood	GM-CSF	GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.632	0.0124	no	no	no	up	no	no	DM-DS
P-hydroxyhippuric acid+urine	GM-CSF	P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	urine_cometabolism	serum_cytokines	0.436	0.0124	no	no	no	up	no	no	DM-DS
acetic acid C2+blood	GM-CSF	acetic acid C2+blood+d18:1-20:1-SM+blood-GUDCA+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.000193	0.0124	up	dn	no	up	no	no	DM-DS
isovaleric acid iso-C5+blood	GM-CSF	isovaleric acid iso-C5+blood+PUFA+blood+SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.117	0.0124	no	no	no	up	no	no	DM-DS
Clostridium	GM-CSF	Clostridium-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-DS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-UDCA+stool+16:0/20:3-PC+blood+UDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-DS
12-ketoDCA+blood	GM-CSF	12-ketoDCA+blood-18:1/18:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.517	0.0124	no	no	no	up	no	no	DM-DS
12-ketoDCA+blood	GM-CSF	12-ketoDCA+blood-18:1/18:0-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.517	0.0124	no	no	no	up	no	no	DM-DS
12-ketoDCA+blood	GM-CSF	12-ketoDCA+blood-18:1/16:1-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.517	0.0124	no	no	no	up	no	no	DM-DS
12-ketoDCA+blood	GM-CSF	12-ketoDCA+blood-16:0/18:0-PS+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.517	0.0124	no	no	no	up	no	no	DM-DS
12-ketoDCA+blood	GM-CSF	12-ketoDCA+blood-16:0/18:1-PE+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.517	0.0124	no	no	no	up	no	no	DM-DS
12-ketoDCA+blood	GM-CSF	12-ketoDCA+blood-18:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.517	0.0124	no	no	no	up	no	no	DM-DS
12-ketoDCA+blood	GM-CSF	12-ketoDCA+blood-16:0/18:0-PS+blood-L-Citrulline+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.517	0.0124	no	no	no	up	no	no	DM-DS
Butyricicoccus	GM-CSF	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF"	Indirect	Genus	serum_cytokines	0.852	0.0124	no	no	no	up	no	no	DM-DS
Blautia	MIP-1a	Blautia-TDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	1.36E-05	0.68	up	dn	dn	no	no	no	DM-DS
Blautia	MIP-1a	Blautia+GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	1.36E-05	0.68	up	dn	dn	no	no	no	DM-DS
Blautia	MIP-1a	Blautia+CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	1.36E-05	0.68	up	dn	dn	no	no	no	DM-DS
Blautia	MIP-1a	Blautia+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	1.36E-05	0.68	up	dn	dn	no	no	no	DM-DS
Parabacteroides	MIP-1a	Parabacteroides-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	4.19E-05	0.68	no	up	up	no	no	no	DM-DS
Parabacteroides	MIP-1a	Parabacteroides+d18:1-22:0-SM+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	4.19E-05	0.68	no	up	up	no	no	no	DM-DS
Dorea	MIP-1a	Dorea+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.00362	0.68	up	no	dn	no	no	no	DM-DS
Dorea	MIP-1a	Dorea+GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.00362	0.68	up	no	dn	no	no	no	DM-DS
Dorea	MIP-1a	Dorea+CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.00362	0.68	up	no	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1a	Faecalibacterium-Phenylacetic acid+stool-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.0039	0.68	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1a	Faecalibacterium+GCDCA+stool+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.0039	0.68	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1a	Faecalibacterium-Phenylacetic acid+stool-16:0/16:1-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.0039	0.68	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1a	Faecalibacterium+GCDCA+stool+16:0/16:1-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.0039	0.68	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1a	Faecalibacterium-Phenylacetic acid+stool-16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.0039	0.68	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1a	Faecalibacterium+GCDCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.0039	0.68	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1a	Faecalibacterium+GCDCA+stool+GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.0039	0.68	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1a	Faecalibacterium-d18:1-16:1-SM+blood+d18:1-22:0-SM+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.0039	0.68	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1a	Faecalibacterium-d18:1-14:0-SM+blood+d18:1-22:0-SM+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.0039	0.68	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1a	Faecalibacterium-Phenylacetic acid+stool-20:3n6+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.0039	0.68	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	MIP-1a	Faecalibacterium+GCDCA+stool+20:3n6+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.0039	0.68	no	dn	dn	no	no	no	DM-DS
TUDCA+blood	MIP-1a	TUDCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.0282	0.68	no	no	dn	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides+18:0/22:6-PC+blood-TDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides+20:3/18:0-PC+blood-TDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	"Bacteroides-Growth hormone synthesis, secretion and action+TDCA+blood-IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides+Longevity regulating pathway - multiple species-TDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides+Parabacteroides-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	"Bacteroides-Growth hormone synthesis, secretion and action-L-Tyrosine+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides+18:0/20:4-PC+blood-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	"Bacteroides-Growth hormone synthesis, secretion and action-CDCA+stool+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides-Pathways in cancer-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides+Leishmaniasis+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides-Relaxin signaling pathway+GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides-cAMP signaling pathway+GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides+18:0/22:6-PC+blood-GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	"Bacteroides-Growth hormone synthesis, secretion and action+GDCA+blood-IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides+Longevity regulating pathway - multiple species-GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides-Long-term depression+GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides+16:0/22:6-PC+blood-20:3n6+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides+18:0/20:4-PC+blood-20:3n6+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	"Bacteroides-Growth hormone synthesis, secretion and action-18:0/18:1-PC+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	"Bacteroides-Growth hormone synthesis, secretion and action-18:0/18:0-PC+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	"Bacteroides-Growth hormone synthesis, secretion and action-GDCA+stool+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides+Glycolysis / Gluconeogenesis+GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides-Long-term depression+Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides+4-hydroxybenzoic acid+urine+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides+18:0/22:6-PE+blood+20:4/18:0-PE+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides-14:0+blood-d18:0-24:1-SM+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides+Legionellosis+d18:0-24:1-SM+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides-14:0+blood-d18:1-22:0-SM+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides+d18:1-20:0-SM+blood+d18:1-22:0-SM+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Bacteroides	MIP-1a	Bacteroides+Parabacteroides+d18:1-22:0-SM+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-DS
Propionic acid+stool	MIP-1a	Propionic acid+stool-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.0436	0.68	dn	no	up	no	no	no	DM-DS
[Ruminococcus]	MIP-1a	[Ruminococcus]+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.0679	0.68	no	no	dn	no	no	no	DM-DS
GUDCA+blood	MIP-1a	GUDCA+blood+TUDCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.0766	0.68	no	no	dn	no	no	no	DM-DS
GUDCA+blood	MIP-1a	GUDCA+blood+HCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.0766	0.68	no	no	dn	no	no	no	DM-DS
GUDCA+blood	MIP-1a	GUDCA+blood+UDCA+blood+Eotaxin-IL-6-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.0766	0.68	no	no	dn	no	no	no	DM-DS
UDCA+blood	MIP-1a	UDCA+blood+Eotaxin-IL-6-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.0939	0.68	no	no	dn	no	no	no	DM-DS
Acetic acid+stool	MIP-1a	Acetic acid+stool-16:0/18:0-PS+blood+20:4/18:0-PE+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.0656	0.68	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	MIP-1a	Acetic acid+stool-18:0/18:0-PS+blood+20:4/18:0-PE+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.0656	0.68	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	MIP-1a	Acetic acid+stool-16:0/18:0-PS+blood-GDCA+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.0656	0.68	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	MIP-1a	Acetic acid+stool-18:0/18:0-PS+blood-GDCA+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.0656	0.68	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	MIP-1a	Acetic acid+stool-18:0/18:0-PS+blood+18:0/18:1-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.0656	0.68	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	MIP-1a	Acetic acid+stool-14:0+blood-d18:0-24:1-SM+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.0656	0.68	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	MIP-1a	Acetic acid+stool-14:0+blood-d18:1-22:0-SM+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.0656	0.68	dn	no	no	no	no	no	DM-DS
Alistipes	MIP-1a	Alistipes-Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.0114	0.68	no	up	no	no	no	no	DM-DS
Alistipes	MIP-1a	Alistipes-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.0114	0.68	no	up	no	no	no	no	DM-DS
Butyricimonas	MIP-1a	Butyricimonas-iso-DCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.17	0.68	no	no	no	no	no	no	DM-DS
Collinsella	MIP-1a	Collinsella+Roseburia+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.128	0.68	no	no	no	no	no	no	DM-DS
5-Hydroxytryptamine+urine	MIP-1a	5-Hydroxytryptamine+urine-Hippuric acid+urine-IL-6-IP-10+MIP-1a	Indirect	urine_cometabolism	serum_cytokines	0.171	0.68	no	no	no	no	no	no	DM-DS
Sarcina	MIP-1a	Sarcina+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.0703	0.68	no	no	no	no	no	no	DM-DS
Methanosphaera	MIP-1a	Methanosphaera-Roseburia+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.0703	0.68	no	no	no	no	no	no	DM-DS
iso-DCA+stool	MIP-1a	iso-DCA+stool+Propionic acid+stool-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.155	0.68	no	no	no	no	no	no	DM-DS
LCA+stool	MIP-1a	LCA+stool-UDCA+stool-TDCA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.314	0.68	no	no	no	no	no	no	DM-DS
LCA+stool	MIP-1a	LCA+stool-UDCA+stool-GDCA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.314	0.68	no	no	no	no	no	no	DM-DS
LCA+stool	MIP-1a	LCA+stool-UDCA+stool+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.314	0.68	no	no	no	no	no	no	DM-DS
LCA+stool	MIP-1a	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.314	0.68	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1a	Akkermansia-Cholinergic synapse+20:4/18:0-PE+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.23	0.68	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1a	Akkermansia-Cholinergic synapse-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.23	0.68	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1a	Akkermansia-Longevity regulating pathway-CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.23	0.68	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1a	Akkermansia-Longevity regulating pathway+GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.23	0.68	no	no	no	no	no	no	DM-DS
Akkermansia	MIP-1a	Akkermansia-Longevity regulating pathway-GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.23	0.68	no	no	no	no	no	no	DM-DS
Bifidobacterium	MIP-1a	Bifidobacterium+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.105	0.68	no	dn	no	no	no	no	DM-DS
3-Hydroxytyramine hydrochloride+urine	MIP-1a	3-Hydroxytyramine hydrochloride+urine-Hippuric acid+urine-IL-6-IP-10+MIP-1a	Indirect	urine_cometabolism	serum_cytokines	0.288	0.68	no	no	no	no	no	no	DM-DS
Ruminococcus	MIP-1a	Ruminococcus+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.335	0.68	no	no	no	no	no	no	DM-DS
GCDCA+blood	MIP-1a	GCDCA+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.31	0.68	no	no	no	no	no	no	DM-DS
ACA+blood	MIP-1a	ACA+blood-decanoic acid C10+blood+L-Phenylalanine+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.338	0.68	no	no	no	no	no	no	DM-DS
ACA+blood	MIP-1a	ACA+blood-decanoic acid C10+blood+L-Isoleucine+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.338	0.68	no	no	no	no	no	no	DM-DS
ACA+blood	MIP-1a	ACA+blood+EPA+blood+TXB2+blood+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.338	0.68	no	no	no	no	no	no	DM-DS
ACA+blood	MIP-1a	ACA+blood-decanoic acid C10+blood-TXB2+blood+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.338	0.68	no	no	no	no	no	no	DM-DS
DCA+stool	MIP-1a	DCA+stool-L-Tryptophan+stool+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.195	0.68	no	no	no	no	no	no	DM-DS
DCA+stool	MIP-1a	DCA+stool-GCA+stool+GDCA+stool+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.195	0.68	no	no	no	no	no	no	DM-DS
DCA+stool	MIP-1a	DCA+stool-GCA+stool-GDCA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.195	0.68	no	no	no	no	no	no	DM-DS
DCA+stool	MIP-1a	DCA+stool-GCA+stool+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.195	0.68	no	no	no	no	no	no	DM-DS
Hippuric acid+urine	MIP-1a	Hippuric acid+urine-IL-6-IP-10+MIP-1a	Indirect	urine_cometabolism	serum_cytokines	0.361	0.68	no	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood-Creatinine+blood+iso-DCA+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood-18:1/20:3-PC+blood-Homovanillic acid+urine-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood-L-Methionine+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool+L-Histidine+blood+L-Methionine+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood-L-Isoleucine+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool+L-Histidine+blood+L-Isoleucine+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood-L-Lysine+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool+L-Histidine+blood+L-Lysine+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood-L-Phenylalanine+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+20:4n6+blood-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+18:0/20:5-PC+blood-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+18:0/20:4-PC+blood-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+d18:1-14:0-SM+blood+d18:1-22:0-SM+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+18:0/22:6-PE+blood+20:4/18:0-PE+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+18:0/18:0-PS+blood+20:4/18:0-PE+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+18:0/22:6-PC+blood-TDCA+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+18:0/22:6-PA+blood-TDCA+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+18:0/22:6-PC+blood-GDCA+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+18:0/22:6-PA+blood-GDCA+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+18:0/18:0-PS+blood-GDCA+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-IL-6-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool+L-Citrulline+blood+Eotaxin-IL-6-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood-20:3-LPC+blood+20:3n6+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood-18:1/20:3-PC+blood+20:3n6+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood-20:3-LPE+blood+20:3n6+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+16:0/22:6-PC+blood-20:3n6+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+18:0/20:5-PC+blood-20:3n6+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+18:0/20:4-PC+blood-20:3n6+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+20:5-LPC+blood+AA+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+18:0/20:5-PC+blood+AA+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+22:6-LPC+blood+AA+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+18:0/18:0-PS+blood+18:0/18:1-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood-18:1/20:3-PC+blood+20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	MIP-1a	Butyric acid+stool-16:0/20:5-PC+blood+18:0/20:5-PC+blood-20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	MIP-1a	4-hydroxybenzoic acid+stool+L-Tryptophan+stool+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.68	no	dn	no	no	no	no	DM-DS
Turicibacter	MIP-1a	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.269	0.68	no	no	no	no	no	no	DM-DS
Turicibacter	MIP-1a	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.269	0.68	no	no	no	no	no	no	DM-DS
Turicibacter	MIP-1a	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.269	0.68	no	no	no	no	no	no	DM-DS
Turicibacter	MIP-1a	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.269	0.68	no	no	no	no	no	no	DM-DS
Turicibacter	MIP-1a	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.269	0.68	no	no	no	no	no	no	DM-DS
Turicibacter	MIP-1a	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.269	0.68	no	no	no	no	no	no	DM-DS
Turicibacter	MIP-1a	Turicibacter+Desulfovibrio+Antigen processing and presentation+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.269	0.68	no	no	no	no	no	no	DM-DS
Turicibacter	MIP-1a	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.269	0.68	no	no	no	no	no	no	DM-DS
Turicibacter	MIP-1a	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.269	0.68	no	no	no	no	no	no	DM-DS
Turicibacter	MIP-1a	Turicibacter+Desulfovibrio+Antigen processing and presentation+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.269	0.68	no	no	no	no	no	no	DM-DS
GCA+blood	MIP-1a	GCA+blood+TDCA+blood-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.16	0.68	no	no	no	no	no	no	DM-DS
ACA+stool	MIP-1a	ACA+stool-L-Phenylalanine+stool-16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.417	0.68	no	no	no	no	no	no	DM-DS
ACA+stool	MIP-1a	ACA+stool-L-Tryptophan+stool+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.417	0.68	no	no	no	no	no	no	DM-DS
ACA+stool	MIP-1a	ACA+stool-L-Phenylalanine+stool+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.417	0.68	no	no	no	no	no	no	DM-DS
CDCA+blood	MIP-1a	CDCA+blood+GCDCA+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.506	0.68	no	no	no	no	no	no	DM-DS
capric acid C6+blood	MIP-1a	capric acid C6+blood-HCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	serum_scfa	serum_cytokines	0.433	0.68	no	no	no	no	no	no	DM-DS
Prevotella	MIP-1a	Prevotella+TDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.287	0.68	no	no	no	no	no	no	DM-DS
Prevotella	MIP-1a	Prevotella+GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.287	0.68	no	no	no	no	no	no	DM-DS
Prevotella	MIP-1a	Prevotella+20:4/18:0-PE+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.287	0.68	no	no	no	no	no	no	DM-DS
TCA+blood	MIP-1a	TCA+blood+TUDCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.339	0.68	no	no	no	no	no	no	DM-DS
iso-DCA+blood	MIP-1a	iso-DCA+blood-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.38	0.68	no	no	no	no	no	no	DM-DS
HCA+stool	MIP-1a	HCA+stool-HDCA+stool-16:0/20:4-PI+blood-AA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.155	0.68	no	no	no	no	no	no	DM-DS
HCA+stool	MIP-1a	HCA+stool-HDCA+stool-16:0/20:4-PI+blood-iso-DCA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.155	0.68	no	no	no	no	no	no	DM-DS
HCA+stool	MIP-1a	HCA+stool-HDCA+stool-16:0/20:4-PI+blood+18:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.155	0.68	no	no	no	no	no	no	DM-DS
HCA+stool	MIP-1a	HCA+stool-HDCA+stool+Eotaxin-IL-6-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.155	0.68	no	no	no	no	no	no	DM-DS
HCA+stool	MIP-1a	HCA+stool-HDCA+stool+Hippuric acid+urine-IL-6-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.155	0.68	no	no	no	no	no	no	DM-DS
HCA+stool	MIP-1a	HCA+stool-HDCA+stool-16:0/20:4-PI+blood+20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.155	0.68	no	no	no	no	no	no	DM-DS
Roseburia	MIP-1a	Roseburia+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.495	0.68	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	MIP-1a	12-ketoDCA+stool-GCA+stool+GDCA+stool+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.505	0.68	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	MIP-1a	12-ketoDCA+stool-GCA+stool-GDCA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.505	0.68	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	MIP-1a	12-ketoDCA+stool-GCA+stool+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.505	0.68	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	MIP-1a	12-ketoDCA+stool+Hippuric acid+urine-IL-6-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.505	0.68	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	MIP-1a	12-ketoDCA+stool+GCA+blood+TDCA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.505	0.68	no	no	no	no	no	no	DM-DS
GLCA+blood	MIP-1a	GLCA+blood+TDCA+blood-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.319	0.68	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	MIP-1a	L-Tryptophan+stool+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.557	0.68	no	no	no	no	no	no	DM-DS
CA+blood	MIP-1a	CA+blood+TDCA+blood-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.606	0.68	no	no	no	no	no	no	DM-DS
GUDCA+stool	MIP-1a	GUDCA+stool+12-HEPE+blood-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.0085	0.68	no	dn	no	no	no	no	DM-DS
L-Phenylalanine+stool	MIP-1a	L-Phenylalanine+stool-16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.398	0.68	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	MIP-1a	L-Phenylalanine+stool+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.398	0.68	no	no	no	no	no	no	DM-DS
GCA+stool	MIP-1a	GCA+stool-GDCA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.0809	0.68	no	no	no	no	no	no	DM-DS
GCA+stool	MIP-1a	GCA+stool+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.0809	0.68	no	no	no	no	no	no	DM-DS
GCA+stool	MIP-1a	GCA+stool+GDCA+stool+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.0809	0.68	no	no	no	no	no	no	DM-DS
Coprococcus	MIP-1a	Coprococcus+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.612	0.68	no	no	no	no	no	no	DM-DS
Coprococcus	MIP-1a	Coprococcus+Roseburia+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.612	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	"Oscillospira-Parathyroid hormone synthesis, secretion and action+TDCA+blood-IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira+JAK-STAT signaling pathway-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira-Vibrio cholerae infection+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira+Platinum drug resistance-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira+Progesterone-mediated oocyte maturation-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira-Rap1 signaling pathway+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira+Spliceosome-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira+T cell receptor signaling pathway-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira+MAPK signaling pathway-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira-Platelet activation+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira+FoxO signaling pathway-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira-Focal adhesion+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira-Human cytomegalovirus infection+20:3n6+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira+MAPK signaling pathway-20:3n6+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira-Human cytomegalovirus infection+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira+MAPK signaling pathway-16:0/16:1-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira-Salivary secretion+20:4/18:0-PE+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira+T cell receptor signaling pathway-20:4/18:0-PE+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira+Platinum drug resistance-Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira+Progesterone-mediated oocyte maturation-Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira-Rap1 signaling pathway+Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira+Spliceosome-Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira-Salivary secretion+Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira+T cell receptor signaling pathway-Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira+MAPK signaling pathway-Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira-Retrograde endocannabinoid signaling-AA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
Oscillospira	MIP-1a	Oscillospira+MAPK signaling pathway+AA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-DS
HCA+blood	MIP-1a	HCA+blood-TXB2+blood+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.544	0.68	no	no	no	no	no	no	DM-DS
iso-LCA+stool	MIP-1a	iso-LCA+stool-UDCA+stool-GDCA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.72	0.68	no	no	no	no	no	no	DM-DS
iso-LCA+stool	MIP-1a	iso-LCA+stool-UDCA+stool-TDCA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.72	0.68	no	no	no	no	no	no	DM-DS
iso-LCA+stool	MIP-1a	iso-LCA+stool-UDCA+stool+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.72	0.68	no	no	no	no	no	no	DM-DS
iso-LCA+stool	MIP-1a	iso-LCA+stool-UDCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.72	0.68	no	no	no	no	no	no	DM-DS
DCA+blood	MIP-1a	DCA+blood+L-Histidine+blood+L-Lysine+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.122	0.68	no	no	no	no	no	no	DM-DS
DCA+blood	MIP-1a	DCA+blood+L-Histidine+blood+L-Isoleucine+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.122	0.68	no	no	no	no	no	no	DM-DS
DCA+blood	MIP-1a	DCA+blood+L-Histidine+blood+L-Methionine+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.122	0.68	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1a	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool+9-HODE+blood+AA+blood-IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.33	0.68	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1a	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.33	0.68	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1a	3-(3-Hydroxyphenyl)propanoic acid+stool-TUDCA+stool-d18:1-14:0-SM+blood+d18:1-22:0-SM+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.33	0.68	no	no	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	MIP-1a	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-6-IP-10+MIP-1a"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.68	up	up	no	no	no	no	DM-DS
nutriCA+blood	MIP-1a	nutriCA+blood+UDCA+blood+Eotaxin-IL-6-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.726	0.68	no	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+urine	MIP-1a	4-hydroxybenzoic acid+urine+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	urine_cometabolism	serum_cytokines	0.52	0.68	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1a	Indole-3-Acetic acid+stool-UDCA+stool-TDCA+blood-IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.68	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1a	Indole-3-Acetic acid+stool-nutriCA+stool+18:0/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.68	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1a	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-20:3n6+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.68	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1a	Indole-3-Acetic acid+stool-nutriCA+stool+20:3n6+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.68	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1a	Indole-3-Acetic acid+stool-nutriCA+stool+18:0/18:1-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.68	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1a	Indole-3-Acetic acid+stool-nutriCA+stool+18:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.68	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1a	Indole-3-Acetic acid+stool-nutriCA+stool+18:0/20:2-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.68	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1a	Indole-3-Acetic acid+stool-nutriCA+stool+20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.68	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1a	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.68	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1a	Indole-3-Acetic acid+stool-nutriCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.68	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1a	Indole-3-Acetic acid+stool-UDCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.68	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1a	Indole-3-Acetic acid+stool-nutriCA+stool-AA+blood-IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.68	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1a	Indole-3-Acetic acid+stool-UDCA+stool-GDCA+blood-IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.68	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1a	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.68	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1a	Indole-3-Acetic acid+stool-UDCA+stool+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.68	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	MIP-1a	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-16:0/16:1-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool+18:1/18:1-PE+blood+20:3n6+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool-18:1/20:4-PC+blood-20:3n6+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool+16:0/18:2-PI+blood+20:3n6+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool+18:1/18:1-PC+blood+20:3n6+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool+18:0/20:3-PI+blood+20:3n6+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool-16:0/22:6-PC+blood-20:3n6+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool-18:0/20:5-PC+blood-20:3n6+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool-18:0/20:4-PC+blood-20:3n6+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool+16:0/18:2-PI+blood+18:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool+18:1/18:1-PE+blood+20:4/18:0-PE+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool+18:1/18:1-PE+blood-AA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool+16:0/18:2-PI+blood-AA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool-18:0/20:5-PC+blood+AA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool-20:4-LPC+blood+AA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool+16:0/18:2-PI+blood+20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool+18:1/18:1-PC+blood+20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool+18:0/20:3-PI+blood+20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool-18:0/20:5-PC+blood-20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool-d18:1-20:1-SM+blood-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool+L-Proline+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool-18:0/20:5-PC+blood-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool-18:0/20:4-PC+blood-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool-20:4-LPC+blood-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool-TXB2+blood+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool+18:1/18:1-PC+blood-Homovanillic acid+urine-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool-d18:1-20:1-SM+blood+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool-20:0/20:5-PC+blood+d18:1-22:0-SM+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
TCA+stool	MIP-1a	TCA+stool-d18:1-20:0-SM+blood+d18:1-22:0-SM+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-DS
HDCA+stool	MIP-1a	HDCA+stool-16:0/20:4-PI+blood-AA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-DS
HDCA+stool	MIP-1a	HDCA+stool-16:0/20:4-PI+blood-iso-DCA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-DS
HDCA+stool	MIP-1a	HDCA+stool-16:0/20:4-PI+blood+18:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-DS
HDCA+stool	MIP-1a	HDCA+stool+Eotaxin-IL-6-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-DS
HDCA+stool	MIP-1a	HDCA+stool+Hippuric acid+urine-IL-6-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-DS
HDCA+stool	MIP-1a	HDCA+stool-16:0/20:4-PI+blood+20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Vibrio cholerae infection+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Carbon metabolism+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Adherens junction+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-p53 signaling pathway-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Platelet activation+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Bacterial invasion of epithelial cells+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-Progesterone-mediated oocyte maturation-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-Platinum drug resistance-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-T cell receptor signaling pathway-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Regulation of actin cytoskeleton+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Rap1 signaling pathway+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-Spliceosome-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-Hippuric acid+urine-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-Signaling pathways regulating pluripotency of stem cells-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Tight junction+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Leukocyte transendothelial migration+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-FoxO signaling pathway-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-ErbB signaling pathway-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Oxytocin signaling pathway+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-JAK-STAT signaling pathway-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-Non-small cell lung cancer-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Focal adhesion+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Fluid shear stress and atherosclerosis+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-NOD-like receptor signaling pathway-20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-Progesterone-mediated oocyte maturation-Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-Platinum drug resistance-Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-T cell receptor signaling pathway-Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Rap1 signaling pathway+Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-Spliceosome-Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-Signaling pathways regulating pluripotency of stem cells-Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Oxytocin signaling pathway+Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Carbon metabolism+CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Proteasome+CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Hippo signaling pathway+CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-NOD-like receptor signaling pathway-18:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-T cell receptor signaling pathway-20:4/18:0-PE+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-Cytosolic DNA-sensing pathway-20:4/18:0-PE+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Hippo signaling pathway+18:0/18:0-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Arrhythmogenic right ventricular cardiomyopathy+18:0/18:0-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Carbon metabolism+GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Proteasome+GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Glycolysis / Gluconeogenesis+GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Proteasome-GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Regulation of actin cytoskeleton-GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Hippo signaling pathway-GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Proteasome+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-ErbB signaling pathway-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+L-Methionine+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Carbon metabolism+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-p53 signaling pathway-Homovanillic acid+urine-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Adherens junction+18:0/18:1-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Hippo signaling pathway+18:0/18:1-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Arrhythmogenic right ventricular cardiomyopathy+18:0/18:1-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira+Thyroid hormone signaling pathway+18:0/18:1-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Lachnospira	MIP-1a	Lachnospira-NOD-like receptor signaling pathway-18:0/18:1-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-DS
Fusobacterium	MIP-1a	Fusobacterium-18:0/18:0-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.628	0.68	no	no	no	no	no	no	DM-DS
Fusobacterium	MIP-1a	Fusobacterium-16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.628	0.68	no	no	no	no	no	no	DM-DS
Fusobacterium	MIP-1a	Fusobacterium-18:0/18:1-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.628	0.68	no	no	no	no	no	no	DM-DS
GCDCA+stool	MIP-1a	GCDCA+stool+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.68	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1a	GCDCA+stool+20:3n6+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.68	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1a	GCDCA+stool+16:0/16:1-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.68	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1a	GCDCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.68	no	dn	no	no	no	no	DM-DS
GCDCA+stool	MIP-1a	GCDCA+stool+GDCA+stool+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.68	no	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:1-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-UDCA+stool-GDCA+blood-IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:2-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-nutriCA+stool+20:3n6+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-UDCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-nutriCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-UDCA+stool+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-nutriCA+stool+20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-UDCA+stool-TDCA+blood-IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-nutriCA+stool-AA+blood-IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Salmonella infection-TDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-GnRH signaling pathway+TDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	"Odoribacter-Growth hormone synthesis, secretion and action+TDCA+blood-IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Endocrine resistance+TDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Chemical carcinogenesis - receptor activation+TDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Longevity regulating pathway - multiple species-TDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Pathogenic Escherichia coli infection+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Antigen processing and presentation+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Leishmaniasis+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Chemical carcinogenesis - receptor activation-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Carbon metabolism+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	"Odoribacter-Growth hormone synthesis, secretion and action-18:0/18:1-PC+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	"Odoribacter-Growth hormone synthesis, secretion and action-18:0/18:0-PC+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Proteasome-GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+GCA+stool-GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-GnRH signaling pathway+GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	"Odoribacter-Growth hormone synthesis, secretion and action+GDCA+blood-IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Endocrine resistance+GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Long-term depression+GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Longevity regulating pathway - multiple species-GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+16:0/20:4-PI+blood+18:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+CA+stool+CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Serotonergic synapse-CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Salmonella infection+CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Proteasome+CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Cocaine addiction-CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Regulation of lipolysis in adipocytes-CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Glutamatergic synapse-CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Insulin secretion-CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-GnRH signaling pathway-CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Cortisol synthesis and secretion-CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	"Odoribacter-Growth hormone synthesis, secretion and action-CDCA+stool+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Endocrine resistance-CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Chemical carcinogenesis - receptor activation-CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Carbon metabolism+CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+16:0/20:4-PI+blood+20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+CA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Antigen processing and presentation+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Chemical carcinogenesis - receptor activation-16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+CA+stool+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Serotonergic synapse-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Proteasome+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+GCA+stool+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	"Odoribacter-Growth hormone synthesis, secretion and action-L-Tyrosine+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Gap junction-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Chemical carcinogenesis - receptor activation-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+16:0/20:4-PI+blood-iso-DCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+CA+stool+GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Serotonergic synapse-GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Proteasome+GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Glycolysis / Gluconeogenesis+GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Glutamatergic synapse-GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+GCA+stool+GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Cortisol synthesis and secretion-GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	"Odoribacter-Growth hormone synthesis, secretion and action-GDCA+stool+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Gap junction-GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Chemical carcinogenesis - receptor activation-GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Carbon metabolism+GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+16:0/20:4-PI+blood-AA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Legionellosis+d18:0-24:1-SM+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Carbon metabolism+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter+Fc gamma R-mediated phagocytosis+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Serotonergic synapse+Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Glutamatergic synapse+Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Gap junction+Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Long-term depression+Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Odoribacter	MIP-1a	Odoribacter-Serotonergic synapse+20:4/18:0-PE+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-DS
Actinomyces	MIP-1a	Actinomyces+Coprococcus+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.621	0.68	no	no	no	no	no	no	DM-DS
Actinomyces	MIP-1a	Actinomyces+Coprococcus+Roseburia+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.621	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool-UDCA+stool-TDCA+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool-nutriCA+stool+18:0/20:2-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool-nutriCA+stool+18:0/18:1-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/16:1-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool-nutriCA+stool+18:0/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool+L-Phenylalanine+stool-16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool-nutriCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool-UDCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool-nutriCA+stool+18:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool-nutriCA+stool-AA+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool+Phenylacetic acid+stool-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool-UDCA+stool+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool+L-Phenylalanine+stool+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool-nutriCA+stool+20:3n6+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool+Phenylacetic acid+stool-20:3n6+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool-nutriCA+stool+20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool-UDCA+stool-GDCA+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	MIP-1a	2-hydroxyphenylacetic acid+urine+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	urine_cometabolism	serum_cytokines	0.763	0.68	no	no	no	no	no	no	DM-DS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool+L-Phenylalanine+stool+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool-nutriCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool+L-Phenylalanine+stool-16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool-nutriCA+stool-AA+blood-IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool-nutriCA+stool+18:0/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool-nutriCA+stool+18:0/20:2-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool-nutriCA+stool+18:0/18:1-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool-nutriCA+stool+20:3n6+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool-nutriCA+stool+20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-DS
Caproic acid+stool	MIP-1a	Caproic acid+stool+Phenylacetic acid+stool-20:3n6+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.882	0.68	no	no	no	no	no	no	DM-DS
Caproic acid+stool	MIP-1a	Caproic acid+stool+Phenylacetic acid+stool-16:0/16:1-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.882	0.68	no	no	no	no	no	no	DM-DS
Caproic acid+stool	MIP-1a	Caproic acid+stool-GCA+stool-GDCA+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.882	0.68	no	no	no	no	no	no	DM-DS
Caproic acid+stool	MIP-1a	Caproic acid+stool+Phenylacetic acid+stool-16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.882	0.68	no	no	no	no	no	no	DM-DS
Caproic acid+stool	MIP-1a	Caproic acid+stool+Phenylacetic acid+stool-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.882	0.68	no	no	no	no	no	no	DM-DS
Caproic acid+stool	MIP-1a	Caproic acid+stool-GCA+stool+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.882	0.68	no	no	no	no	no	no	DM-DS
Caproic acid+stool	MIP-1a	Caproic acid+stool-GCA+stool+GDCA+stool+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.882	0.68	no	no	no	no	no	no	DM-DS
Eggerthella	MIP-1a	Eggerthella+24:1+blood-d18:0-24:1-SM+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.912	0.68	no	no	no	no	no	no	DM-DS
Eggerthella	MIP-1a	Eggerthella+Phosphatidylinositol signaling system-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.912	0.68	no	no	no	no	no	no	DM-DS
Eggerthella	MIP-1a	Eggerthella+nutriCA+stool+20:3n6+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.912	0.68	no	no	no	no	no	no	DM-DS
Eggerthella	MIP-1a	Eggerthella+nutriCA+stool+20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.912	0.68	no	no	no	no	no	no	DM-DS
Eggerthella	MIP-1a	Eggerthella+nutriCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.912	0.68	no	no	no	no	no	no	DM-DS
Eggerthella	MIP-1a	Eggerthella+nutriCA+stool-AA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.912	0.68	no	no	no	no	no	no	DM-DS
Eggerthella	MIP-1a	Eggerthella+AMPK signaling pathway-CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.912	0.68	no	no	no	no	no	no	DM-DS
Eggerthella	MIP-1a	Eggerthella+nutriCA+stool+18:0/18:0-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.912	0.68	no	no	no	no	no	no	DM-DS
Eggerthella	MIP-1a	Eggerthella+nutriCA+stool+18:0/18:1-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.912	0.68	no	no	no	no	no	no	DM-DS
Eggerthella	MIP-1a	Eggerthella+nutriCA+stool+18:0/20:2-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.912	0.68	no	no	no	no	no	no	DM-DS
Eggerthella	MIP-1a	Eggerthella+AMPK signaling pathway+TDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.912	0.68	no	no	no	no	no	no	DM-DS
Eggerthella	MIP-1a	Eggerthella+nutriCA+stool+18:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.912	0.68	no	no	no	no	no	no	DM-DS
Anaerotruncus	MIP-1a	Anaerotruncus-Ruminococcus+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.904	0.68	no	no	no	no	no	no	DM-DS
Anaerostipes	MIP-1a	Anaerostipes-Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.568	0.68	no	no	no	no	no	no	DM-DS
Anaerostipes	MIP-1a	Anaerostipes-TDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.568	0.68	no	no	no	no	no	no	DM-DS
Anaerostipes	MIP-1a	Anaerostipes-GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.568	0.68	no	no	no	no	no	no	DM-DS
Anaerostipes	MIP-1a	Anaerostipes-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.568	0.68	no	no	no	no	no	no	DM-DS
TUDCA+stool	MIP-1a	TUDCA+stool+9-HODE+blood+AA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.241	0.68	no	no	no	no	no	no	DM-DS
TUDCA+stool	MIP-1a	TUDCA+stool-d18:1-14:0-SM+blood+d18:1-22:0-SM+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.241	0.68	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	MIP-1a	Isovaleric acid+stool-UDCA+stool-GDCA+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.343	0.68	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	MIP-1a	Isovaleric acid+stool-UDCA+stool-TDCA+blood-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.343	0.68	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	MIP-1a	Isovaleric acid+stool+Phenylacetic acid+stool-20:3n6+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.343	0.68	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	MIP-1a	Isovaleric acid+stool+Phenylacetic acid+stool-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.343	0.68	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	MIP-1a	Isovaleric acid+stool-UDCA+stool+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.343	0.68	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	MIP-1a	Isovaleric acid+stool+L-Phenylalanine+stool+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.343	0.68	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	MIP-1a	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/16:1-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.343	0.68	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	MIP-1a	Isovaleric acid+stool+L-Phenylalanine+stool-16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.343	0.68	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	MIP-1a	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.343	0.68	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	MIP-1a	Isovaleric acid+stool-UDCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_scfa	serum_cytokines	0.343	0.68	no	no	no	no	no	no	DM-DS
Paraprevotella	MIP-1a	Paraprevotella+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-DS
Homovanillic acid+urine	MIP-1a	Homovanillic acid+urine-IP-10+MIP-1a	Indirect	urine_cometabolism	serum_cytokines	0.45	0.68	no	no	no	no	no	no	DM-DS
TDCA+blood	MIP-1a	TDCA+blood-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.155	0.68	no	up	no	no	no	no	DM-DS
¦Ø-MCA+stool	MIP-1a	¦Ø-MCA+stool+GDCA+stool+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.919	0.68	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	MIP-1a	¦Ø-MCA+stool+CDCA+stool+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.919	0.68	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1a	Phenylacetic acid+stool-16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.785	0.68	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1a	Phenylacetic acid+stool-16:0/16:1-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.785	0.68	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1a	Phenylacetic acid+stool-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.785	0.68	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	MIP-1a	Phenylacetic acid+stool-20:3n6+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.785	0.68	no	no	no	no	no	no	DM-DS
Gemmiger	MIP-1a	Gemmiger+ErbB signaling pathway-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.595	0.68	no	no	no	no	no	no	DM-DS
Gemmiger	MIP-1a	Gemmiger+Signaling pathways regulating pluripotency of stem cells-Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.595	0.68	no	no	no	no	no	no	DM-DS
Gemmiger	MIP-1a	Gemmiger+24:0+blood-Homovanillic acid+urine-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.595	0.68	no	no	no	no	no	no	DM-DS
Gemmiger	MIP-1a	Gemmiger+Colorectal cancer-Homovanillic acid+urine-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.595	0.68	no	no	no	no	no	no	DM-DS
Gemmiger	MIP-1a	Gemmiger+Gastric cancer-Homovanillic acid+urine-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.595	0.68	no	no	no	no	no	no	DM-DS
Gemmiger	MIP-1a	Gemmiger+Signaling pathways regulating pluripotency of stem cells-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.595	0.68	no	no	no	no	no	no	DM-DS
Gemmiger	MIP-1a	Gemmiger+Pathways in cancer-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.595	0.68	no	no	no	no	no	no	DM-DS
Gemmiger	MIP-1a	Gemmiger+ErbB signaling pathway-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.595	0.68	no	no	no	no	no	no	DM-DS
Gemmiger	MIP-1a	Gemmiger+Gastric cancer-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.595	0.68	no	no	no	no	no	no	DM-DS
GDCA+stool	MIP-1a	GDCA+stool+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.656	0.68	no	no	no	no	no	no	DM-DS
Methanobrevibacter	MIP-1a	Methanobrevibacter-Alcoholism-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.629	0.68	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	MIP-1a	L-Tyrosine+stool-nutriCA+stool+20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.68	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	MIP-1a	L-Tyrosine+stool-nutriCA+stool+20:3n6+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.68	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	MIP-1a	L-Tyrosine+stool-nutriCA+stool+18:0/18:1-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.68	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	MIP-1a	L-Tyrosine+stool-nutriCA+stool+18:0/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.68	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	MIP-1a	L-Tyrosine+stool-nutriCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.68	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	MIP-1a	L-Tyrosine+stool-nutriCA+stool+18:0/20:2-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.68	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	MIP-1a	L-Tyrosine+stool+9-HODE+blood+AA+blood-IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.68	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	MIP-1a	L-Tyrosine+stool-nutriCA+stool-AA+blood-IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.68	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	MIP-1a	L-Tyrosine+stool-nutriCA+stool+18:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.68	no	no	no	no	no	no	DM-DS
CDCA+stool	MIP-1a	CDCA+stool+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.663	0.68	no	no	no	no	no	no	DM-DS
CA+stool	MIP-1a	CA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.827	0.68	no	no	no	no	no	no	DM-DS
CA+stool	MIP-1a	CA+stool+GDCA+stool+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.827	0.68	no	no	no	no	no	no	DM-DS
CA+stool	MIP-1a	CA+stool+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.827	0.68	no	no	no	no	no	no	DM-DS
CA+stool	MIP-1a	CA+stool+CDCA+stool+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.827	0.68	no	no	no	no	no	no	DM-DS
HDCA+blood	MIP-1a	HDCA+blood+Hypotaurine+blood+iso-DCA+blood-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.483	0.68	no	no	no	no	no	no	DM-DS
UDCA+stool	MIP-1a	UDCA+stool-GDCA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.266	0.68	no	no	no	no	no	no	DM-DS
UDCA+stool	MIP-1a	UDCA+stool+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.266	0.68	no	no	no	no	no	no	DM-DS
UDCA+stool	MIP-1a	UDCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.266	0.68	no	no	no	no	no	no	DM-DS
UDCA+stool	MIP-1a	UDCA+stool-TDCA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.266	0.68	no	no	no	no	no	no	DM-DS
TDCA+stool	MIP-1a	TDCA+stool-12-ketoDCA+blood+d18:1-22:0-SM+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.963	0.68	no	no	no	no	no	no	DM-DS
TDCA+stool	MIP-1a	TDCA+stool-12-ketoDCA+blood+d18:0-24:1-SM+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.963	0.68	no	no	no	no	no	no	DM-DS
TDCA+stool	MIP-1a	TDCA+stool-12-ketoDCA+blood-20:4/18:0-PE+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.963	0.68	no	no	no	no	no	no	DM-DS
TDCA+stool	MIP-1a	TDCA+stool-12-ketoDCA+blood+GDCA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.963	0.68	no	no	no	no	no	no	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	MIP-1a	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A-IL-1b-IL-2-IP-10+MIP-1a	Indirect	urine_cometabolism	serum_cytokines	0.973	0.68	no	no	no	no	no	no	DM-DS
Desulfovibrio	MIP-1a	Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.27	0.68	no	no	no	no	no	no	DM-DS
Desulfovibrio	MIP-1a	Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.27	0.68	no	no	no	no	no	no	DM-DS
Desulfovibrio	MIP-1a	Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.27	0.68	no	no	no	no	no	no	DM-DS
Desulfovibrio	MIP-1a	Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.27	0.68	no	no	no	no	no	no	DM-DS
Desulfovibrio	MIP-1a	Desulfovibrio+Human T-cell leukemia virus 1 infection+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.27	0.68	no	no	no	no	no	no	DM-DS
Desulfovibrio	MIP-1a	Desulfovibrio+Human cytomegalovirus infection+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.27	0.68	no	no	no	no	no	no	DM-DS
Desulfovibrio	MIP-1a	Desulfovibrio+Human immunodeficiency virus 1 infection+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.27	0.68	no	no	no	no	no	no	DM-DS
Desulfovibrio	MIP-1a	Desulfovibrio+Antigen processing and presentation+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.27	0.68	no	no	no	no	no	no	DM-DS
Desulfovibrio	MIP-1a	Desulfovibrio+Herpes simplex virus 1 infection+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.27	0.68	no	no	no	no	no	no	DM-DS
Desulfovibrio	MIP-1a	Desulfovibrio+Antigen processing and presentation+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.27	0.68	no	no	no	no	no	no	DM-DS
nutriCA+stool	MIP-1a	nutriCA+stool+18:0/18:1-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.481	0.68	no	no	no	no	no	no	DM-DS
nutriCA+stool	MIP-1a	nutriCA+stool+18:0/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.481	0.68	no	no	no	no	no	no	DM-DS
nutriCA+stool	MIP-1a	nutriCA+stool-AA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.481	0.68	no	no	no	no	no	no	DM-DS
nutriCA+stool	MIP-1a	nutriCA+stool+20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.481	0.68	no	no	no	no	no	no	DM-DS
nutriCA+stool	MIP-1a	nutriCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.481	0.68	no	no	no	no	no	no	DM-DS
nutriCA+stool	MIP-1a	nutriCA+stool+18:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.481	0.68	no	no	no	no	no	no	DM-DS
nutriCA+stool	MIP-1a	nutriCA+stool+18:0/20:2-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.481	0.68	no	no	no	no	no	no	DM-DS
nutriCA+stool	MIP-1a	nutriCA+stool+20:3n6+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.481	0.68	no	no	no	no	no	no	DM-DS
Bilophila	MIP-1a	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.528	0.68	no	no	no	no	no	no	DM-DS
Bilophila	MIP-1a	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+20:3n6+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.528	0.68	no	no	no	no	no	no	DM-DS
Bilophila	MIP-1a	Bilophila+Desulfovibrio+Human cytomegalovirus infection+20:3n6+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.528	0.68	no	no	no	no	no	no	DM-DS
Bilophila	MIP-1a	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+20:3n6+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.528	0.68	no	no	no	no	no	no	DM-DS
Bilophila	MIP-1a	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.528	0.68	no	no	no	no	no	no	DM-DS
Bilophila	MIP-1a	Bilophila+Desulfovibrio+Human cytomegalovirus infection+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.528	0.68	no	no	no	no	no	no	DM-DS
Bilophila	MIP-1a	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.528	0.68	no	no	no	no	no	no	DM-DS
Bilophila	MIP-1a	Bilophila+Desulfovibrio+Antigen processing and presentation+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.528	0.68	no	no	no	no	no	no	DM-DS
Bilophila	MIP-1a	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.528	0.68	no	no	no	no	no	no	DM-DS
Bilophila	MIP-1a	Bilophila+Desulfovibrio+Antigen processing and presentation+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.528	0.68	no	no	no	no	no	no	DM-DS
GDCA+blood	MIP-1a	GDCA+blood-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.632	0.68	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	MIP-1a	P-hydroxyhippuric acid+urine+Eotaxin-IL-6-IP-10+MIP-1a	Indirect	urine_cometabolism	serum_cytokines	0.436	0.68	no	no	no	no	no	no	DM-DS
acetic acid C2+blood	MIP-1a	acetic acid C2+blood+d18:1-18:1-SM+blood+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	serum_scfa	serum_cytokines	0.000193	0.68	up	dn	no	no	no	no	DM-DS
acetic acid C2+blood	MIP-1a	acetic acid C2+blood+d18:1-20:1-SM+blood+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	serum_scfa	serum_cytokines	0.000193	0.68	up	dn	no	no	no	no	DM-DS
acetic acid C2+blood	MIP-1a	acetic acid C2+blood+d18:1-20:1-SM+blood-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	serum_scfa	serum_cytokines	0.000193	0.68	up	dn	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	MIP-1a	isovaleric acid iso-C5+blood-L-Phenylalanine+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	serum_scfa	serum_cytokines	0.117	0.68	no	no	no	no	no	no	DM-DS
Clostridium	MIP-1a	Clostridium+GDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.925	0.68	no	no	no	no	no	no	DM-DS
Clostridium	MIP-1a	Clostridium-GDCA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.925	0.68	no	no	no	no	no	no	DM-DS
Clostridium	MIP-1a	Clostridium+CDCA+stool+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.925	0.68	no	no	no	no	no	no	DM-DS
Clostridium	MIP-1a	Clostridium+20:3n6+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.925	0.68	no	no	no	no	no	no	DM-DS
Clostridium	MIP-1a	Clostridium+18:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.925	0.68	no	no	no	no	no	no	DM-DS
Clostridium	MIP-1a	Clostridium+20:2/18:0-PC+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.925	0.68	no	no	no	no	no	no	DM-DS
Clostridium	MIP-1a	Clostridium+Homovanillic acid+urine-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.925	0.68	no	no	no	no	no	no	DM-DS
Clostridium	MIP-1a	Clostridium+IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.925	0.68	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	MIP-1a	T-¦Á-MCA+stool-UDCA+stool-TDCA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.48	0.68	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	MIP-1a	T-¦Á-MCA+stool-UDCA+stool+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.48	0.68	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	MIP-1a	T-¦Á-MCA+stool-UDCA+stool+16:0/20:3-PC+blood+IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.48	0.68	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	MIP-1a	T-¦Á-MCA+stool-UDCA+stool-GDCA+blood-IP-10+MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.48	0.68	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	MIP-1a	12-ketoDCA+blood+GDCA+blood-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.517	0.68	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	MIP-1a	12-ketoDCA+blood+d18:0-24:1-SM+blood+IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.517	0.68	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	MIP-1a	12-ketoDCA+blood-20:4/18:0-PE+blood-IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.517	0.68	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	MIP-1a	12-ketoDCA+blood+d18:1-22:0-SM+blood+IP-10+MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.517	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood+18:1/18:1-PE+blood+20:3n6+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood+16:0/18:1-PE+blood+20:3n6+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood+18:1/18:0-PE+blood+20:3n6+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood+18:1/16:1-PE+blood+20:3n6+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood+20:3n6+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood-20:0+blood-Homovanillic acid+urine-IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	Butyricicoccus-18:2/20:4-PC+blood+20:0+blood-Homovanillic acid+urine-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood+9,10-EPOME+blood+Homovanillic acid+urine-IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood-d18:1-20:1-SM+blood+Homovanillic acid+urine-IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood+18:1/18:1-PE+blood+20:4/18:0-PE+blood-IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood+18:1/18:1-PE+blood-AA+blood-IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood+16:0/18:1-PE+blood-AA+blood-IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood+18:1/18:0-PE+blood-AA+blood-IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	Butyricicoccus-18:2/20:4-PC+blood+20:4-LPC+blood+AA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood+18:1/16:1-PE+blood-AA+blood-IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	Butyricicoccus-18:2/20:4-PC+blood+20:3/16:0-PC+blood+AA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood-AA+blood-IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	Butyricicoccus+TUDCA+stool+9-HODE+blood+AA+blood-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	Butyricicoccus+TUDCA+stool-d18:1-14:0-SM+blood+d18:1-22:0-SM+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood-20:0-LPC+blood+d18:1-22:0-SM+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	Butyricicoccus-18:2/20:4-PC+blood+20:0-LPC+blood+d18:1-22:0-SM+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood-d18:1-20:0-SM+blood+d18:1-22:0-SM+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	Butyricicoccus-18:2/20:4-PC+blood-L-Phenylalanine+blood+L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood-20:1-LPE+blood-L-Tyrosine+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	Butyricicoccus-18:2/20:4-PC+blood+20:4n6+blood-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	Butyricicoccus-18:2/20:4-PC+blood+20:4-LPC+blood-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood-20:0+blood-L-Tyrosine+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	Butyricicoccus-18:2/20:4-PC+blood+20:0+blood-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood-20:4-LPE+blood-L-Tyrosine+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	Butyricicoccus-18:2/20:4-PC+blood+20:4-LPE+blood-L-Tyrosine+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood-d18:1-20:1-SM+blood-L-Tyrosine+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	Butyricicoccus-18:2/20:4-PC+blood+Hippuric acid+urine-IL-6-IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood+18:0/20:3-PC+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood-20:1-LPE+blood+d18:0-24:1-SM+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood-20:0-LPC+blood+d18:0-24:1-SM+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	Butyricicoccus-18:2/20:4-PC+blood+20:0-LPC+blood+d18:0-24:1-SM+blood+IP-10+MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Butyricicoccus	MIP-1a	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood+20:2/18:0-PC+blood+IP-10+MIP-1a"	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-DS
Blautia	IL-17A	Blautia+Longevity regulating pathway - multiple species-Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia+Longevity regulating pathway - multiple species+Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia+Peroxisome+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia+d18:1-18:0-SM+blood+n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia-Calcium signaling pathway-n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia+Peroxisome+B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia+Peroxisome+Apoptosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia+Peroxisome+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia-Dopaminergic synapse-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia+Peroxisome-Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia-Dopaminergic synapse+Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia+Peroxisome+Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia-Dopaminergic synapse-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia-Dopaminergic synapse-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia+Longevity regulating pathway - multiple species-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia-Dopaminergic synapse-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia+CDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia-Dopaminergic synapse-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia-Calcium signaling pathway-16:1/16:1-PC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia-Calcium signaling pathway-18:3n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Blautia	IL-17A	Blautia+Dorea-Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-DS
Parabacteroides	IL-17A	Parabacteroides-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	4.19E-05	0.855	no	up	up	no	no	no	DM-DS
Dorea	IL-17A	Dorea-Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	DM-DS
Faecalibacterium	IL-17A	Faecalibacterium-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0039	0.855	no	dn	dn	no	no	no	DM-DS
Faecalibacterium	IL-17A	Faecalibacterium+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0039	0.855	no	dn	dn	no	no	no	DM-DS
Bacteroides	IL-17A	Bacteroides-Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.000267	0.855	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-17A	Bacteroides-cAMP signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.000267	0.855	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-17A	Bacteroides+16:1/16:1-PC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.000267	0.855	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-17A	Bacteroides-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.000267	0.855	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-17A	Bacteroides-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.000267	0.855	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-17A	Bacteroides-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.000267	0.855	dn	dn	up	no	no	no	DM-DS
Bacteroides	IL-17A	Bacteroides-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.000267	0.855	dn	dn	up	no	no	no	DM-DS
Propionic acid+stool	IL-17A	Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A	Indirect	stool_scfa	serum_cytokines	0.0436	0.855	dn	no	up	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Shigellosis-n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-18:0/20:4-PC+blood+n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-18:1/20:4-PC+blood+n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-18:0/20:5-PC+blood+n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Tight junction-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-ErbB signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-JAK-STAT signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-MicroRNAs in cancer+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-Pathways in cancer+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-ErbB signaling pathway-Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-ErbB signaling pathway+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-JAK-STAT signaling pathway+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Huntington disease-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Non-alcoholic fatty liver disease-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-MicroRNAs in cancer+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-Pathways in cancer+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Alzheimer disease-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Parkinson disease-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-ErbB signaling pathway+Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-JAK-STAT signaling pathway+Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-JAK-STAT signaling pathway+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Huntington disease-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Non-alcoholic fatty liver disease-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Alzheimer disease-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Parkinson disease-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Tight junction-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-JAK-STAT signaling pathway+Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells-16:1/16:1-PC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-Gastric cancer-16:1/16:1-PC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-Platinum drug resistance+Ribosome biogenesis in eukaryotes-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Tight junction-Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-ErbB signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-JAK-STAT signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-FoxO signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-ErbB signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-JAK-STAT signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Tight junction-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-ErbB signaling pathway+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-JAK-STAT signaling pathway+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-MicroRNAs in cancer+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-Pathways in cancer+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Tight junction-B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-ErbB signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-JAK-STAT signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Tight junction-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-Signaling pathways regulating pluripotency of stem cells+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-FoxO signaling pathway+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-ErbB signaling pathway+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-JAK-STAT signaling pathway+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Huntington disease-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Non-alcoholic fatty liver disease-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-MicroRNAs in cancer+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-Pathways in cancer+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Alzheimer disease-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Parkinson disease-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-18:0/20:4-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+18:0/18:1-PE+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Tight junction-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-FoxO signaling pathway+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-ErbB signaling pathway+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-JAK-STAT signaling pathway+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Huntington disease-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]+Alzheimer disease-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-Progesterone-mediated oocyte maturation+Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-Platinum drug resistance+Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
[Ruminococcus]	IL-17A	[Ruminococcus]-Progesterone-mediated oocyte maturation-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-DS
GUDCA+blood	IL-17A	GUDCA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A	Indirect	serum_bileacids	serum_cytokines	0.0766	0.855	no	no	dn	no	no	no	DM-DS
UDCA+blood	IL-17A	UDCA+blood+Eotaxin-GM-CSF-IL-17A	Indirect	serum_bileacids	serum_cytokines	0.0939	0.855	no	no	dn	no	no	no	DM-DS
Acetic acid+stool	IL-17A	Acetic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A	Indirect	stool_scfa	serum_cytokines	0.0656	0.855	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	IL-17A	Acetic acid+stool-16:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.0656	0.855	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	IL-17A	Acetic acid+stool-18:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.0656	0.855	dn	no	no	no	no	no	DM-DS
Acetic acid+stool	IL-17A	Acetic acid+stool+L-Histidine+blood-n3+blood-FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.0656	0.855	dn	no	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Vibrio cholerae infection-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+T cell receptor signaling pathway+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Platelet activation-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Ferroptosis+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+Platinum drug resistance+Ribosome biogenesis in eukaryotes-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Influenza A-Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+MAPK signaling pathway+Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+Platinum drug resistance+Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Rap1 signaling pathway-Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Ferroptosis-Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Ferroptosis+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Ferroptosis+Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+T cell receptor signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-18:2/16:0-PC+blood+18:3n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+18:0-LPC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+T cell receptor signaling pathway-Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Vibrio cholerae infection-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+T cell receptor signaling pathway+Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Platelet activation-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Oxytocin signaling pathway-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Salivary secretion-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Alcoholism+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Ferroptosis+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Vibrio cholerae infection-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+T cell receptor signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+Signaling pathways regulating pluripotency of stem cells+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Platelet activation-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Oxytocin signaling pathway-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Salivary secretion-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+Colorectal cancer-16:1/16:1-PC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+Signaling pathways regulating pluripotency of stem cells-16:1/16:1-PC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+Gastric cancer-16:1/16:1-PC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+T cell receptor signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Platelet activation-Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+MAPK signaling pathway-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Vibrio cholerae infection-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+T cell receptor signaling pathway+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+Signaling pathways regulating pluripotency of stem cells+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Platelet activation-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Oxytocin signaling pathway-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Rap1 signaling pathway-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Salivary secretion-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Vibrio cholerae infection-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+T cell receptor signaling pathway+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+Signaling pathways regulating pluripotency of stem cells+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Platelet activation-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Oxytocin signaling pathway-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Salivary secretion-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes+MAPK signaling pathway+n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-DMG+blood-n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Platelet activation-Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Oxytocin signaling pathway-Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Alistipes	IL-17A	Alistipes-Rap1 signaling pathway-Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-DS
Butyricimonas	IL-17A	Butyricimonas+Cholinergic synapse-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.17	0.855	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-17A	Butyricimonas+20:5n3+blood+n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.17	0.855	no	no	no	no	no	no	DM-DS
Butyricimonas	IL-17A	Butyricimonas+Cholinergic synapse+n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.17	0.855	no	no	no	no	no	no	DM-DS
Collinsella	IL-17A	Collinsella-Renin secretion-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-DS
Collinsella	IL-17A	Collinsella-Inflammatory mediator regulation of TRP channels-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-DS
Collinsella	IL-17A	Collinsella-Renin secretion-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-DS
Collinsella	IL-17A	Collinsella-Inflammatory mediator regulation of TRP channels-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-DS
Collinsella	IL-17A	Collinsella-Inflammatory mediator regulation of TRP channels+Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-DS
Collinsella	IL-17A	Collinsella-Renin secretion-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-DS
Collinsella	IL-17A	Collinsella-Inflammatory mediator regulation of TRP channels-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-DS
Collinsella	IL-17A	Collinsella-Renin secretion-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-DS
Collinsella	IL-17A	Collinsella-Inflammatory mediator regulation of TRP channels-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-DS
Collinsella	IL-17A	Collinsella-Renin secretion-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-DS
Collinsella	IL-17A	Collinsella-Inflammatory mediator regulation of TRP channels-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-DS
Collinsella	IL-17A	Collinsella-Renin secretion-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-DS
Collinsella	IL-17A	Collinsella-Inflammatory mediator regulation of TRP channels-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-DS
Collinsella	IL-17A	Collinsella-Renin secretion-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-DS
Collinsella	IL-17A	Collinsella-Inflammatory mediator regulation of TRP channels-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-DS
Sarcina	IL-17A	Sarcina+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0703	0.855	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-17A	Methanosphaera-Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.0703	0.855	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-17A	Methanosphaera-Roseburia+16:0/16:1-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0703	0.855	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-17A	Methanosphaera-Roseburia+16:0/16:1-PC+blood-n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0703	0.855	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-17A	Methanosphaera-Roseburia+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0703	0.855	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-17A	Methanosphaera-Roseburia+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0703	0.855	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-17A	Methanosphaera-Roseburia+16:0/16:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0703	0.855	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-17A	Methanosphaera-Roseburia+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0703	0.855	no	no	no	no	no	no	DM-DS
Methanosphaera	IL-17A	Methanosphaera-Roseburia-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0703	0.855	no	no	no	no	no	no	DM-DS
iso-DCA+stool	IL-17A	iso-DCA+stool+Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A	Indirect	stool_bileacids	serum_cytokines	0.155	0.855	no	no	no	no	no	no	DM-DS
LCA+stool	IL-17A	LCA+stool-UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.314	0.855	no	no	no	no	no	no	DM-DS
LCA+stool	IL-17A	LCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.314	0.855	no	no	no	no	no	no	DM-DS
LCA+stool	IL-17A	LCA+stool-UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.314	0.855	no	no	no	no	no	no	DM-DS
Akkermansia	IL-17A	Akkermansia+Proteoglycans in cancer-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	DM-DS
Akkermansia	IL-17A	Akkermansia-Cholinergic synapse-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	DM-DS
Akkermansia	IL-17A	Akkermansia-Cholinergic synapse+n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	DM-DS
Akkermansia	IL-17A	Akkermansia-Cytokine-cytokine receptor interaction+16:1/16:1-PC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	DM-DS
Akkermansia	IL-17A	Akkermansia+Proteoglycans in cancer-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	DM-DS
Akkermansia	IL-17A	Akkermansia-Cytokine-cytokine receptor interaction-Cytosolic DNA-sensing pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	DM-DS
Akkermansia	IL-17A	Akkermansia+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Glutamatergic synapse+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Gastric acid secretion-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Autophagy - animal+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+HIF-1 signaling pathway-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Proteasome-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-GABAergic synapse+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Proteoglycans in cancer-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Transcriptional misregulation in cancer+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Hepatitis B+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Glycolysis / Gluconeogenesis-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-MicroRNAs in cancer+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Focal adhesion-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Hippo signaling pathway-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Autophagy - animal+B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+HIF-1 signaling pathway-B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Proteasome-B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Tight junction-B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Glycolysis / Gluconeogenesis-B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Focal adhesion-B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Hippo signaling pathway-B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Adherens junction-B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Autophagy - animal+Apoptosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+HIF-1 signaling pathway-Apoptosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Proteasome-Apoptosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Glycolysis / Gluconeogenesis-Apoptosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Autophagy - animal+Cytosolic DNA-sensing pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Focal adhesion-Cytosolic DNA-sensing pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Autophagy - animal+Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+HIF-1 signaling pathway-Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Proteasome-Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-FoxO signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Glycolysis / Gluconeogenesis-Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Focal adhesion-Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Hippo signaling pathway-Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Adherens junction-Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Autophagy - animal+Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Proteasome-Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Tight junction-Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Glycolysis / Gluconeogenesis-Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Focal adhesion-Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Hippo signaling pathway-Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Adherens junction-Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-18:0/20:4-PI+blood+n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+DMG+blood-n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Glutamatergic synapse+Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Autophagy - animal+Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+HIF-1 signaling pathway-Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Proteasome-Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Glycolysis / Gluconeogenesis-Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Focal adhesion-Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Hippo signaling pathway-Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Vibrio cholerae infection-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Gastric acid secretion-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Autophagy - animal+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Proteasome-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Transcriptional misregulation in cancer+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Tight junction-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Hepatitis B+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Bacterial invasion of epithelial cells-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Glycolysis / Gluconeogenesis-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-MicroRNAs in cancer+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Focal adhesion-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Hippo signaling pathway-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Adherens junction-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Vibrio cholerae infection-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Gastric acid secretion-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Autophagy - animal+Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Tight junction-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Focal adhesion-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Hippo signaling pathway-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Adherens junction-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Vibrio cholerae infection-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Gastric acid secretion-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Autophagy - animal+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Proteasome-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Transcriptional misregulation in cancer+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Tight junction-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Hepatitis B+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Bacterial invasion of epithelial cells-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Glycolysis / Gluconeogenesis-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-MicroRNAs in cancer+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Focal adhesion-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Hippo signaling pathway-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Adherens junction-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Vibrio cholerae infection-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Thyroid hormone signaling pathway-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Gastric acid secretion-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Autophagy - animal+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+HIF-1 signaling pathway-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Proteasome-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-GABAergic synapse+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-FoxO signaling pathway+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Proteoglycans in cancer-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Transcriptional misregulation in cancer+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Tight junction-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Hepatitis B+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Bacterial invasion of epithelial cells-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Glycolysis / Gluconeogenesis-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-MicroRNAs in cancer+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Focal adhesion-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Hippo signaling pathway-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Adherens junction-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Proteasome-cAMP signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Glycolysis / Gluconeogenesis-cAMP signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Autophagy - animal-Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Proteasome+Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-GABAergic synapse-Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Focal adhesion+Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Hippo signaling pathway+Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Glutamatergic synapse+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Autophagy - animal+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+HIF-1 signaling pathway-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Proteasome-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-GABAergic synapse+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Glycolysis / Gluconeogenesis-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Hippo signaling pathway-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Leukocyte transendothelial migration-Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Glutamatergic synapse+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Vibrio cholerae infection-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Thyroid hormone signaling pathway-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Gastric acid secretion-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-Autophagy - animal+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+HIF-1 signaling pathway-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Proteasome-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-GABAergic synapse+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium-FoxO signaling pathway+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Tight junction-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Bacterial invasion of epithelial cells-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Glycolysis / Gluconeogenesis-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Focal adhesion-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Hippo signaling pathway-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Adherens junction-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Bifidobacterium	IL-17A	Bifidobacterium+Leukocyte transendothelial migration-Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-DS
Ruminococcus	IL-17A	Ruminococcus-n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.335	0.855	no	no	no	no	no	no	DM-DS
Ruminococcus	IL-17A	Ruminococcus-18:3n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.335	0.855	no	no	no	no	no	no	DM-DS
GCDCA+blood	IL-17A	GCDCA+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.31	0.855	no	no	no	no	no	no	DM-DS
ACA+blood	IL-17A	ACA+blood+EPA+blood+n3+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.338	0.855	no	no	no	no	no	no	DM-DS
ACA+blood	IL-17A	ACA+blood-decanoic acid C10+blood-n3+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.338	0.855	no	no	no	no	no	no	DM-DS
DCA+stool	IL-17A	DCA+stool+HDCA+stool+Eotaxin-GM-CSF-IL-17A	Indirect	stool_bileacids	serum_cytokines	0.195	0.855	no	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-17A	Butyric acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A	Indirect	stool_scfa	serum_cytokines	0.102	0.855	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-17A	Butyric acid+stool+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A	Indirect	stool_scfa	serum_cytokines	0.102	0.855	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-17A	Butyric acid+stool-16:0/20:5-PC+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.102	0.855	dn	no	no	no	no	no	DM-DS
Butyric acid+stool	IL-17A	Butyric acid+stool+L-Histidine+blood-n3+blood-FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.102	0.855	dn	no	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	IL-17A	4-hydroxybenzoic acid+stool-DCA+stool+HDCA+stool+Eotaxin-GM-CSF-IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.855	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	IL-17A	4-hydroxybenzoic acid+stool-iso-LCA+stool-TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.855	no	dn	no	no	no	no	DM-DS
4-hydroxybenzoic acid+stool	IL-17A	4-hydroxybenzoic acid+stool-iso-LCA+stool-TCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.855	no	dn	no	no	no	no	DM-DS
Turicibacter	IL-17A	Turicibacter+Desulfovibrio+Herpes simplex virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.269	0.855	no	no	no	no	no	no	DM-DS
Turicibacter	IL-17A	Turicibacter+Desulfovibrio+Human cytomegalovirus infection+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.269	0.855	no	no	no	no	no	no	DM-DS
Turicibacter	IL-17A	Turicibacter+Desulfovibrio+Human immunodeficiency virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.269	0.855	no	no	no	no	no	no	DM-DS
Turicibacter	IL-17A	Turicibacter+Desulfovibrio+Antigen processing and presentation+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.269	0.855	no	no	no	no	no	no	DM-DS
Turicibacter	IL-17A	Turicibacter+Desulfovibrio+Human T-cell leukemia virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.269	0.855	no	no	no	no	no	no	DM-DS
Turicibacter	IL-17A	Turicibacter+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.269	0.855	no	no	no	no	no	no	DM-DS
GCA+blood	IL-17A	GCA+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.16	0.855	no	no	no	no	no	no	DM-DS
ACA+stool	IL-17A	ACA+stool-L-Phenylalanine+stool-16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.417	0.855	no	no	no	no	no	no	DM-DS
ACA+stool	IL-17A	ACA+stool-L-Phenylalanine+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.417	0.855	no	no	no	no	no	no	DM-DS
ACA+stool	IL-17A	ACA+stool-L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A	Indirect	stool_bileacids	serum_cytokines	0.417	0.855	no	no	no	no	no	no	DM-DS
CDCA+blood	IL-17A	CDCA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A	Indirect	serum_bileacids	serum_cytokines	0.506	0.855	no	no	no	no	no	no	DM-DS
capric acid C6+blood	IL-17A	capric acid C6+blood-HCA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A	Indirect	serum_scfa	serum_cytokines	0.433	0.855	no	no	no	no	no	no	DM-DS
Prevotella	IL-17A	Prevotella+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-DS
Prevotella	IL-17A	Prevotella+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-DS
iso-DCA+blood	IL-17A	iso-DCA+blood+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A	Indirect	serum_bileacids	serum_cytokines	0.38	0.855	no	no	no	no	no	no	DM-DS
HCA+stool	IL-17A	HCA+stool-HDCA+stool+Eotaxin-GM-CSF-IL-17A	Indirect	stool_bileacids	serum_cytokines	0.155	0.855	no	no	no	no	no	no	DM-DS
Roseburia	IL-17A	Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.495	0.855	no	no	no	no	no	no	DM-DS
Roseburia	IL-17A	Roseburia+16:0/16:1-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.495	0.855	no	no	no	no	no	no	DM-DS
Roseburia	IL-17A	Roseburia+16:0/16:1-PC+blood-n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.495	0.855	no	no	no	no	no	no	DM-DS
Roseburia	IL-17A	Roseburia+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.495	0.855	no	no	no	no	no	no	DM-DS
Roseburia	IL-17A	Roseburia+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.495	0.855	no	no	no	no	no	no	DM-DS
Roseburia	IL-17A	Roseburia+16:0/16:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.495	0.855	no	no	no	no	no	no	DM-DS
Roseburia	IL-17A	Roseburia+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.495	0.855	no	no	no	no	no	no	DM-DS
Roseburia	IL-17A	Roseburia-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.495	0.855	no	no	no	no	no	no	DM-DS
12-ketoDCA+stool	IL-17A	12-ketoDCA+stool+HDCA+stool+Eotaxin-GM-CSF-IL-17A	Indirect	stool_bileacids	serum_cytokines	0.505	0.855	no	no	no	no	no	no	DM-DS
GLCA+blood	IL-17A	GLCA+blood-SFA+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A	Indirect	serum_bileacids	serum_cytokines	0.319	0.855	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-17A	L-Tryptophan+stool+8-HETE+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.557	0.855	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-17A	L-Tryptophan+stool-18:3n6+blood-22:0/16:0-PE+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.557	0.855	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-17A	L-Tryptophan+stool-18:3n6+blood-L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.557	0.855	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-17A	L-Tryptophan+stool+8-HETE+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.557	0.855	no	no	no	no	no	no	DM-DS
L-Tryptophan+stool	IL-17A	L-Tryptophan+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.557	0.855	no	no	no	no	no	no	DM-DS
CA+blood	IL-17A	CA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A	Indirect	serum_bileacids	serum_cytokines	0.606	0.855	no	no	no	no	no	no	DM-DS
GUDCA+stool	IL-17A	GUDCA+stool+12-HEPE+blood-DMG+blood-n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0085	0.855	no	dn	no	no	no	no	DM-DS
GUDCA+stool	IL-17A	GUDCA+stool+12-HEPE+blood+16:0/20:5-PC+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0085	0.855	no	dn	no	no	no	no	DM-DS
GUDCA+stool	IL-17A	GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0085	0.855	no	dn	no	no	no	no	DM-DS
L-Phenylalanine+stool	IL-17A	L-Phenylalanine+stool-16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.398	0.855	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	IL-17A	L-Phenylalanine+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.398	0.855	no	no	no	no	no	no	DM-DS
L-Phenylalanine+stool	IL-17A	L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.398	0.855	no	no	no	no	no	no	DM-DS
GCA+stool	IL-17A	GCA+stool+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	DM-DS
Coprococcus	IL-17A	Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	DM-DS
Coprococcus	IL-17A	Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	DM-DS
Coprococcus	IL-17A	Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	DM-DS
Coprococcus	IL-17A	Coprococcus+Roseburia+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	DM-DS
Coprococcus	IL-17A	Coprococcus+Roseburia+16:0/16:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	DM-DS
Coprococcus	IL-17A	Coprococcus+Roseburia-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	DM-DS
Coprococcus	IL-17A	Coprococcus+16:0/16:0-PC+blood+18:0/18:2-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	DM-DS
Coprococcus	IL-17A	Coprococcus+16:0/16:0-PC+blood+18:1/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	DM-DS
Coprococcus	IL-17A	Coprococcus+Roseburia+16:0/16:1-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	DM-DS
Coprococcus	IL-17A	Coprococcus+16:0/16:0-PC+blood-18:0-LPC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	DM-DS
Coprococcus	IL-17A	Coprococcus+Roseburia+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	DM-DS
Coprococcus	IL-17A	Coprococcus+Roseburia+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	DM-DS
Coprococcus	IL-17A	Coprococcus+16:0/16:0-PC+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	DM-DS
Coprococcus	IL-17A	Coprococcus+16:0/16:0-PC+blood+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	DM-DS
Coprococcus	IL-17A	Coprococcus+Roseburia+16:0/16:1-PC+blood-n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	DM-DS
Coprococcus	IL-17A	Coprococcus+16:0/16:0-PC+blood+22:0/16:0-PE+blood+n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Calcium signaling pathway-18:3n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Calcium signaling pathway-16:1/16:1-PC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+JAK-STAT signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Ribosome-Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vascular smooth muscle contraction-Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Oxidative phosphorylation-Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Autophagy - animal+Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+NF-kappa B signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Cardiac muscle contraction-Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+FoxO signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Focal adhesion-Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+JAK-STAT signaling pathway+Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Autophagy - animal+Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+NF-kappa B signaling pathway+Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Focal adhesion-Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+JAK-STAT signaling pathway+Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vibrio cholerae infection-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Dopaminergic synapse-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Morphine addiction-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Renin secretion-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vasopressin-regulated water reabsorption-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Melanogenesis-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Inflammatory mediator regulation of TRP channels-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Salivary secretion-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vascular smooth muscle contraction-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+T cell receptor signaling pathway+Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Platelet activation-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Gastric acid secretion-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Autophagy - animal+Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Circadian entrainment-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+NF-kappa B signaling pathway+Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Pancreatic secretion-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Focal adhesion-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Calcium signaling pathway-n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Shigellosis-n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+MAPK signaling pathway+n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+JAK-STAT signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vascular smooth muscle contraction-Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+T cell receptor signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Platelet activation-Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Autophagy - animal+Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Circadian entrainment-Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+NF-kappa B signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Focal adhesion-Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Thermogenesis+Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Dopaminergic synapse+Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Inflammatory mediator regulation of TRP channels+Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vascular smooth muscle contraction+Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+T cell receptor signaling pathway-Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Autophagy - animal-Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Circadian entrainment+Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+NF-kappa B signaling pathway-Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Focal adhesion+Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Ribosome-Apoptosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Oxidative phosphorylation-Apoptosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Autophagy - animal+Apoptosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+NF-kappa B signaling pathway+Apoptosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+NF-kappa B signaling pathway+Sphingolipid signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Autophagy - animal+Cytosolic DNA-sensing pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+NF-kappa B signaling pathway+Cytosolic DNA-sensing pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Focal adhesion-Cytosolic DNA-sensing pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Thermogenesis-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+JAK-STAT signaling pathway+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Ribosome-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Prion disease-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Huntington disease-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Alzheimer disease-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Coronavirus disease - COVID-19-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Retrograde endocannabinoid signaling-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Renin secretion-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Hepatitis B+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Melanogenesis-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Inflammatory mediator regulation of TRP channels-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vascular smooth muscle contraction-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Oxidative phosphorylation-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Gastric acid secretion-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Autophagy - animal+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Non-alcoholic fatty liver disease-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Circadian entrainment-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+NF-kappa B signaling pathway+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Pathways of neurodegeneration - multiple diseases-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Cardiac muscle contraction-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Parkinson disease-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Focal adhesion-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Thermogenesis-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+JAK-STAT signaling pathway+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Ribosome-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Prion disease-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Huntington disease-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Alzheimer disease-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Retrograde endocannabinoid signaling-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Renin secretion-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Melanogenesis-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Inflammatory mediator regulation of TRP channels-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Oxidative phosphorylation-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Autophagy - animal+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Non-alcoholic fatty liver disease-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+NF-kappa B signaling pathway+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Pathways of neurodegeneration - multiple diseases-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Cardiac muscle contraction-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Parkinson disease-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Thermogenesis-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+JAK-STAT signaling pathway+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vibrio cholerae infection-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Prion disease-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Dopaminergic synapse-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Retrograde endocannabinoid signaling-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Renin secretion-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Hepatitis B+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vasopressin-regulated water reabsorption-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Melanogenesis-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Inflammatory mediator regulation of TRP channels-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Salivary secretion-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vascular smooth muscle contraction-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+T cell receptor signaling pathway+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Platelet activation-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Oxidative phosphorylation-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Gastric acid secretion-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Autophagy - animal+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Circadian entrainment-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+NF-kappa B signaling pathway+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Focal adhesion-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Thermogenesis-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+JAK-STAT signaling pathway+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vibrio cholerae infection-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Ribosome-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Prion disease-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Huntington disease-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Alzheimer disease-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Dopaminergic synapse-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Coronavirus disease - COVID-19-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Retrograde endocannabinoid signaling-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Renin secretion-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Hepatitis B+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Rap1 signaling pathway-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vasopressin-regulated water reabsorption-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Melanogenesis-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Inflammatory mediator regulation of TRP channels-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Salivary secretion-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vascular smooth muscle contraction-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+T cell receptor signaling pathway+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Platelet activation-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Oxidative phosphorylation-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Gastric acid secretion-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Autophagy - animal+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Non-alcoholic fatty liver disease-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Circadian entrainment-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+NF-kappa B signaling pathway+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Pathways of neurodegeneration - multiple diseases-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Cardiac muscle contraction-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+FoxO signaling pathway+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Parkinson disease-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Focal adhesion-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+JAK-STAT signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Ribosome-B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vascular smooth muscle contraction-B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+T cell receptor signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Oxidative phosphorylation-B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Autophagy - animal+B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+NF-kappa B signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Cardiac muscle contraction-B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Focal adhesion-B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+JAK-STAT signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vibrio cholerae infection-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Dopaminergic synapse-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Retrograde endocannabinoid signaling-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Renin secretion-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Hepatitis B+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Inflammatory mediator regulation of TRP channels-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Salivary secretion-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vascular smooth muscle contraction-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+T cell receptor signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Platelet activation-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Gastric acid secretion-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Autophagy - animal+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Circadian entrainment-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+NF-kappa B signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Focal adhesion-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Thermogenesis-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+JAK-STAT signaling pathway+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vibrio cholerae infection-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Ribosome-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Prion disease-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Huntington disease-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Alzheimer disease-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Dopaminergic synapse-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Retrograde endocannabinoid signaling-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Renin secretion-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Melanogenesis-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Inflammatory mediator regulation of TRP channels-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Vascular smooth muscle contraction-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+T cell receptor signaling pathway+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Platelet activation-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Oxidative phosphorylation-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Gastric acid secretion-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Autophagy - animal+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Circadian entrainment-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+NF-kappa B signaling pathway+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Cardiac muscle contraction-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+FoxO signaling pathway+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Focal adhesion-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Platinum drug resistance+Ribosome biogenesis in eukaryotes-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Platinum drug resistance+Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Progesterone-mediated oocyte maturation+Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Human cytomegalovirus infection-Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Rap1 signaling pathway-Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Spliceosome+Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+MAPK signaling pathway+Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Progesterone-mediated oocyte maturation-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Human cytomegalovirus infection+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+MAPK signaling pathway-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Progesterone-mediated oocyte maturation+Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Rap1 signaling pathway-Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira+Spliceosome+Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
Oscillospira	IL-17A	Oscillospira-Platelet activation-Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-DS
HCA+blood	IL-17A	HCA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A	Indirect	serum_bileacids	serum_cytokines	0.544	0.855	no	no	no	no	no	no	DM-DS
iso-LCA+stool	IL-17A	iso-LCA+stool-TCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.72	0.855	no	no	no	no	no	no	DM-DS
iso-LCA+stool	IL-17A	iso-LCA+stool-TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.72	0.855	no	no	no	no	no	no	DM-DS
DCA+blood	IL-17A	DCA+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.122	0.855	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-DMG+blood-n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood+16:0/20:5-PC+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-DS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool-GUDCA+stool+12-HEPE+blood-L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-DS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-17A	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF-IL-17A"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.855	up	up	no	no	no	no	DM-DS
nutriCA+blood	IL-17A	nutriCA+blood+UDCA+blood+Eotaxin-GM-CSF-IL-17A	Indirect	serum_bileacids	serum_cytokines	0.726	0.855	no	no	no	no	no	no	DM-DS
Indole-3-Acetic acid+stool	IL-17A	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.304	0.855	no	no	no	no	no	no	DM-DS
TCA+stool	IL-17A	TCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-DS
TCA+stool	IL-17A	TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-DS
HDCA+stool	IL-17A	HDCA+stool+Eotaxin-GM-CSF-IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-DS
Lachnospira	IL-17A	Lachnospira-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.279	0.855	no	no	no	no	no	no	DM-DS
Lachnospira	IL-17A	Lachnospira-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.279	0.855	no	no	no	no	no	no	DM-DS
Lachnospira	IL-17A	Lachnospira-Cytosolic DNA-sensing pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.279	0.855	no	no	no	no	no	no	DM-DS
Lachnospira	IL-17A	Lachnospira-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.279	0.855	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-17A	Fusobacterium-18:0/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.628	0.855	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-17A	Fusobacterium+16:0-LPC+blood-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.628	0.855	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-17A	Fusobacterium-16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.628	0.855	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-17A	Fusobacterium-18:0/18:2-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.628	0.855	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-17A	Fusobacterium-18:0/18:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.628	0.855	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-17A	Fusobacterium-18:1/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.628	0.855	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-17A	Fusobacterium-18:0/18:0-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.628	0.855	no	no	no	no	no	no	DM-DS
Fusobacterium	IL-17A	Fusobacterium-18:0/18:1-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.628	0.855	no	no	no	no	no	no	DM-DS
GCDCA+stool	IL-17A	GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-nutriCA+stool+18:1/20:3-PC+blood-n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-nutriCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:1-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:2-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-nutriCA+stool+18:1/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-DS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-nutriCA+stool+18:0/18:0-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Proteasome-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Glycolysis / Gluconeogenesis-Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Glutamatergic synapse+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	"Odoribacter-Growth hormone synthesis, secretion and action+Acute myeloid leukemia+FGF basic+IL-17A"	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Ferroptosis+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Fc gamma R-mediated phagocytosis+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Proteasome-Apoptosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Glycolysis / Gluconeogenesis-Apoptosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Neuroactive ligand-receptor interaction+Apoptosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Antigen processing and presentation+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Proteasome-B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Glycolysis / Gluconeogenesis-B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Neuroactive ligand-receptor interaction+B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Proteasome-cAMP signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Glycolysis / Gluconeogenesis-cAMP signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Proteasome-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Glycolysis / Gluconeogenesis-Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Glutamatergic synapse+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	"Odoribacter-Growth hormone synthesis, secretion and action+Chagas disease+FGF basic+IL-17A"	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Long-term depression+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Ferroptosis+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Proteasome-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Glycolysis / Gluconeogenesis-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	"Odoribacter-Growth hormone synthesis, secretion and action+Chronic myeloid leukemia+FGF basic+IL-17A"	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Longevity regulating pathway - multiple species-Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Proteasome+Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Fc gamma R-mediated phagocytosis-Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Morphine addiction-Hepatitis C+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Proteasome-Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Glycolysis / Gluconeogenesis-Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Neuroactive ligand-receptor interaction+Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Pathogenic Escherichia coli infection-Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Necroptosis-Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Long-term depression-Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Ferroptosis-Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Longevity regulating pathway - multiple species+Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Endocrine resistance-Sphingolipid signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Proteasome-Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Glycolysis / Gluconeogenesis-Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Necroptosis-n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Serotonergic synapse+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Proteasome-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Glycolysis / Gluconeogenesis-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Glutamatergic synapse+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	"Odoribacter-Growth hormone synthesis, secretion and action+Amoebiasis+FGF basic+IL-17A"	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Neuroactive ligand-receptor interaction+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Leishmaniasis-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Gap junction+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Legionellosis-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Long-term depression+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Ferroptosis+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Fc gamma R-mediated phagocytosis+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Proteasome-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Glycolysis / Gluconeogenesis-Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Proteasome-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Glycolysis / Gluconeogenesis-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	"Odoribacter-Growth hormone synthesis, secretion and action+Small cell lung cancer+FGF basic+IL-17A"	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Serotonergic synapse+Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Proteasome-Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Glycolysis / Gluconeogenesis-Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Glutamatergic synapse+Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Gap junction+Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Necroptosis+Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Long-term depression+Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Carbon metabolism-Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-Ferroptosis+Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Longevity regulating pathway - multiple species-Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter-HDCA+stool+Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+Neuroactive ligand-receptor interaction-Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Odoribacter	IL-17A	Odoribacter+16:0/20:4-PI+blood-Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-DS
Actinomyces	IL-17A	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.621	0.855	no	no	no	no	no	no	DM-DS
Actinomyces	IL-17A	Actinomyces+Coprococcus-Propionic acid+stool+P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.621	0.855	no	no	no	no	no	no	DM-DS
Actinomyces	IL-17A	Actinomyces+Coprococcus+16:0/16:0-PC+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.621	0.855	no	no	no	no	no	no	DM-DS
Actinomyces	IL-17A	Actinomyces+Coprococcus+Roseburia+GCDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.621	0.855	no	no	no	no	no	no	DM-DS
Actinomyces	IL-17A	Actinomyces+Coprococcus+Roseburia+16:0/16:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.621	0.855	no	no	no	no	no	no	DM-DS
Actinomyces	IL-17A	Actinomyces+Coprococcus+Roseburia-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.621	0.855	no	no	no	no	no	no	DM-DS
Actinomyces	IL-17A	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:0/18:2-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.621	0.855	no	no	no	no	no	no	DM-DS
Actinomyces	IL-17A	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:1/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.621	0.855	no	no	no	no	no	no	DM-DS
Actinomyces	IL-17A	Actinomyces+Coprococcus+Roseburia+16:0/16:1-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.621	0.855	no	no	no	no	no	no	DM-DS
Actinomyces	IL-17A	Actinomyces+Coprococcus+16:0/16:0-PC+blood-18:0-LPC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.621	0.855	no	no	no	no	no	no	DM-DS
Actinomyces	IL-17A	Actinomyces+Coprococcus+Roseburia+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.621	0.855	no	no	no	no	no	no	DM-DS
Actinomyces	IL-17A	Actinomyces+Coprococcus+Roseburia+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.621	0.855	no	no	no	no	no	no	DM-DS
Actinomyces	IL-17A	Actinomyces+Coprococcus+16:0/16:0-PC+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.621	0.855	no	no	no	no	no	no	DM-DS
Actinomyces	IL-17A	Actinomyces+Coprococcus+16:0/16:0-PC+blood+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.621	0.855	no	no	no	no	no	no	DM-DS
Actinomyces	IL-17A	Actinomyces+Coprococcus+Roseburia+16:0/16:1-PC+blood-n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.621	0.855	no	no	no	no	no	no	DM-DS
Actinomyces	IL-17A	Actinomyces+Coprococcus+16:0/16:0-PC+blood+22:0/16:0-PE+blood+n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.621	0.855	no	no	no	no	no	no	DM-DS
Isobutyric acid+stool	IL-17A	Isobutyric acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.408	0.855	no	no	no	no	no	no	DM-DS
2-hydroxyphenylacetic acid+urine	IL-17A	"2-hydroxyphenylacetic acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-GM-CSF-IL-17A"	Indirect	urine_cometabolism	serum_cytokines	0.763	0.855	no	no	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool+L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool+L-Phenylalanine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool-nutriCA+stool+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool-nutriCA+stool+18:1/20:3-PC+blood-n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool+L-Phenylalanine+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool-nutriCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool+L-Phenylalanine+stool-16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool-nutriCA+stool+18:0/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool-nutriCA+stool+18:0/18:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool-nutriCA+stool+18:0/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool-nutriCA+stool+18:0/18:0-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool-nutriCA+stool+18:1/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool-nutriCA+stool+18:0/20:2-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-DS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool-nutriCA+stool+18:0/18:1-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-DS
Caproic acid+stool	IL-17A	Caproic acid+stool-TCA+stool+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.882	0.855	no	no	no	no	no	no	DM-DS
Caproic acid+stool	IL-17A	Caproic acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.882	0.855	no	no	no	no	no	no	DM-DS
Caproic acid+stool	IL-17A	Caproic acid+stool-TCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.882	0.855	no	no	no	no	no	no	DM-DS
Eggerthella	IL-17A	Eggerthella-Yersinia infection+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.912	0.855	no	no	no	no	no	no	DM-DS
Eggerthella	IL-17A	Eggerthella+Phosphatidylinositol signaling system-Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.912	0.855	no	no	no	no	no	no	DM-DS
Eggerthella	IL-17A	Eggerthella-Yersinia infection-Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.912	0.855	no	no	no	no	no	no	DM-DS
Eggerthella	IL-17A	Eggerthella+Phosphatidylinositol signaling system+Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.912	0.855	no	no	no	no	no	no	DM-DS
Eggerthella	IL-17A	Eggerthella-Influenza A-Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.912	0.855	no	no	no	no	no	no	DM-DS
Eggerthella	IL-17A	Eggerthella+AMPK signaling pathway-Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.912	0.855	no	no	no	no	no	no	DM-DS
Eggerthella	IL-17A	Eggerthella+Phosphatidylinositol signaling system-Cytosolic DNA-sensing pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.912	0.855	no	no	no	no	no	no	DM-DS
Eggerthella	IL-17A	Eggerthella+Phosphatidylinositol signaling system+Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.912	0.855	no	no	no	no	no	no	DM-DS
Eggerthella	IL-17A	Eggerthella+Phosphatidylinositol signaling system-Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.912	0.855	no	no	no	no	no	no	DM-DS
Eggerthella	IL-17A	Eggerthella+Phosphatidylinositol signaling system-Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.912	0.855	no	no	no	no	no	no	DM-DS
Eggerthella	IL-17A	Eggerthella+AMPK signaling pathway-Apoptosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.912	0.855	no	no	no	no	no	no	DM-DS
Eggerthella	IL-17A	Eggerthella+Phosphatidylinositol signaling system-Apoptosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.912	0.855	no	no	no	no	no	no	DM-DS
Eggerthella	IL-17A	Eggerthella+AMPK signaling pathway-B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.912	0.855	no	no	no	no	no	no	DM-DS
Eggerthella	IL-17A	Eggerthella+Phosphatidylinositol signaling system-B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.912	0.855	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-17A	Anaerotruncus-Ruminococcus-n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.904	0.855	no	no	no	no	no	no	DM-DS
Anaerotruncus	IL-17A	Anaerotruncus-Ruminococcus-18:3n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.904	0.855	no	no	no	no	no	no	DM-DS
Anaerostipes	IL-17A	Anaerostipes+Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.568	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-DHA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool+9-HODE+blood+AA+blood+DHA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-d18:1-14:0-SM+blood+d18:1-14:1-SM+blood-DHA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool+9-HODE+blood-d18:1-14:1-SM+blood-DHA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood+L-Proline+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-L-2-Aminobutyric acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool+9-HODE+blood+AA+blood+L-2-Aminobutyric acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-L-2-Aminobutyric acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:3/16:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:3/18:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-20:3/18:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:5/18:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-d18:1-18:0-SM+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:2-PC+blood-d18:1-18:0-SM+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-EPA+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool+9-HODE+blood+AA+blood+EPA+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-22:6n3+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-d18:1-14:0-SM+blood+d18:1-20:0-SM+blood-decanoic acid C10+blood-n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood-Creatinine+blood+DMG+blood-n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood+DMG+blood-n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood-DMG+blood-n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood+16:0/20:5-PC+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood-DL-methionine sulfoxide+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-d18:1-14:0-SM+blood-Ethanolamine+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-d18:1-14:0-SM+blood-L-Asparagine+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood+18:2-LPE+blood-n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-20:5n3+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood+18:1/18:0-PS+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood+18:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:1/20:4-PC+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:2-PC+blood-20:1/20:4-PC+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:1-PC+blood-20:1/20:4-PC+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-20:5/18:0-PC+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-22:0/16:0-PE+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-22:6-LPC+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:2-PC+blood+18:3-LPC+blood+18:3n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+18:2/18:1-PC+blood+18:3-LPC+blood+18:3n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood+18:3-LPC+blood+18:3n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood-18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+18:0+blood+18:1/18:1-PG+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+16:0/18:3-PC+blood-18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+20:0/20:4-PE+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF-IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool+9-HODE+blood+AA+blood+L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF-IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+14:1/18:2-PG+blood-L-2-Aminobutyric acid+blood+Eotaxin-GM-CSF-IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood+24:0+blood-P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-d18:1-14:0-SM+blood-L-Asparagine+blood+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-d18:1-14:0-SM+blood-Glycine+blood-UDCA+blood+Eotaxin-GM-CSF-IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
TUDCA+stool	IL-17A	TUDCA+stool-14:0/18:2-PC+blood-18:2-LPA+blood-UDCA+blood+Eotaxin-GM-CSF-IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-DS
Isovaleric acid+stool	IL-17A	Isovaleric acid+stool+Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.343	0.855	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-17A	Paraprevotella-Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-DS
Paraprevotella	IL-17A	Paraprevotella+Ribosome biogenesis in eukaryotes-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-DS
¦Ø-MCA+stool	IL-17A	¦Ø-MCA+stool+CDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.919	0.855	no	no	no	no	no	no	DM-DS
Phenylacetic acid+stool	IL-17A	Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.785	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+Pathways in cancer+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+ErbB signaling pathway+Chronic myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+ErbB signaling pathway+Neurotrophin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+Pathways in cancer+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+ErbB signaling pathway+Prostate cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+Signaling pathways regulating pluripotency of stem cells+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+Pathways in cancer+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+ErbB signaling pathway+Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+ErbB signaling pathway+Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+Pathways in cancer+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+ErbB signaling pathway+Acute myeloid leukemia+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+Signaling pathways regulating pluripotency of stem cells-16:1/16:1-PC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+Colorectal cancer-16:1/16:1-PC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+Gastric cancer-16:1/16:1-PC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+ErbB signaling pathway+Chagas disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+ErbB signaling pathway+B cell receptor signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+ErbB signaling pathway+Fc epsilon RI signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
Gemmiger	IL-17A	Gemmiger+ErbB signaling pathway-Estrogen signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-DS
GDCA+stool	IL-17A	GDCA+stool-Phenylacetic acid+stool-18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-DS
GDCA+stool	IL-17A	GDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-DS
Methanobrevibacter	IL-17A	Methanobrevibacter-Alcoholism+Amoebiasis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.629	0.855	no	no	no	no	no	no	DM-DS
L-Tyrosine+stool	IL-17A	L-Tyrosine+stool-UDCA+blood+Eotaxin-GM-CSF-IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.44	0.855	no	no	no	no	no	no	DM-DS
CDCA+stool	IL-17A	CDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.663	0.855	no	no	no	no	no	no	DM-DS
CA+stool	IL-17A	CA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.827	0.855	no	no	no	no	no	no	DM-DS
CA+stool	IL-17A	CA+stool+CDCA+stool+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.827	0.855	no	no	no	no	no	no	DM-DS
HDCA+blood	IL-17A	HDCA+blood+Hypotaurine+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.483	0.855	no	no	no	no	no	no	DM-DS
HDCA+blood	IL-17A	HDCA+blood+Hypotaurine+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.483	0.855	no	no	no	no	no	no	DM-DS
HDCA+blood	IL-17A	HDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A	Indirect	serum_bileacids	serum_cytokines	0.483	0.855	no	no	no	no	no	no	DM-DS
UDCA+stool	IL-17A	UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.266	0.855	no	no	no	no	no	no	DM-DS
UDCA+stool	IL-17A	UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.266	0.855	no	no	no	no	no	no	DM-DS
UDCA+stool	IL-17A	UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.266	0.855	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-17A	TDCA+stool-12-ketoDCA+blood-18:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.963	0.855	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-17A	TDCA+stool-12-ketoDCA+blood-18:0/22:6-PI+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.963	0.855	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-17A	TDCA+stool-12-ketoDCA+blood-18:0/22:6-PE+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.963	0.855	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-17A	TDCA+stool-12-ketoDCA+blood-18:1/22:6-PE+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.963	0.855	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-17A	TDCA+stool-12-ketoDCA+blood-16:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.963	0.855	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-17A	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PE+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.963	0.855	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-17A	TDCA+stool-12-ketoDCA+blood-16:1/18:1-PG+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.963	0.855	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-17A	TDCA+stool-12-ketoDCA+blood-18:0/18:1-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.963	0.855	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-17A	TDCA+stool-12-ketoDCA+blood-18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.963	0.855	no	no	no	no	no	no	DM-DS
TDCA+stool	IL-17A	TDCA+stool-12-ketoDCA+blood-18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.963	0.855	no	no	no	no	no	no	DM-DS
4-hydroxy-3-methoxymandelic acid+urine	IL-17A	4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	urine_cometabolism	serum_cytokines	0.973	0.855	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-17A	Desulfovibrio+Human T-cell leukemia virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.27	0.855	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-17A	Desulfovibrio+Human cytomegalovirus infection+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.27	0.855	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-17A	Desulfovibrio+Human immunodeficiency virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.27	0.855	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-17A	Desulfovibrio+Antigen processing and presentation+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.27	0.855	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-17A	Desulfovibrio+Herpes simplex virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.27	0.855	no	no	no	no	no	no	DM-DS
Desulfovibrio	IL-17A	Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.27	0.855	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-17A	nutriCA+stool+18:0/22:6-PA+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.481	0.855	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-17A	nutriCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.481	0.855	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-17A	nutriCA+stool+18:0/18:1-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.481	0.855	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-17A	nutriCA+stool+18:0/18:0-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.481	0.855	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-17A	nutriCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.481	0.855	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-17A	nutriCA+stool+18:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.481	0.855	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-17A	nutriCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.481	0.855	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-17A	nutriCA+stool+18:0/18:1-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.481	0.855	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-17A	nutriCA+stool+18:0/18:0-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.481	0.855	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-17A	nutriCA+stool+18:1/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.481	0.855	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-17A	nutriCA+stool+18:0/20:3-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.481	0.855	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-17A	nutriCA+stool+18:0/20:2-PC+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.481	0.855	no	no	no	no	no	no	DM-DS
nutriCA+stool	IL-17A	nutriCA+stool+18:1/20:3-PC+blood-n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.481	0.855	no	no	no	no	no	no	DM-DS
Bilophila	IL-17A	Bilophila+Desulfovibrio+Human T-cell leukemia virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.528	0.855	no	no	no	no	no	no	DM-DS
Bilophila	IL-17A	Bilophila+Desulfovibrio+Human cytomegalovirus infection+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.528	0.855	no	no	no	no	no	no	DM-DS
Bilophila	IL-17A	Bilophila+Desulfovibrio+Human immunodeficiency virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.528	0.855	no	no	no	no	no	no	DM-DS
Bilophila	IL-17A	Bilophila+Desulfovibrio+Antigen processing and presentation+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.528	0.855	no	no	no	no	no	no	DM-DS
Bilophila	IL-17A	Bilophila+Desulfovibrio+Herpes simplex virus 1 infection+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.528	0.855	no	no	no	no	no	no	DM-DS
Bilophila	IL-17A	Bilophila+Desulfovibrio+Human cytomegalovirus infection-Primary immunodeficiency-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.528	0.855	no	no	no	no	no	no	DM-DS
GDCA+blood	IL-17A	GDCA+blood+Hypotaurine+blood+L-Citrulline+blood+Eotaxin-GM-CSF-IL-17A	Indirect	serum_bileacids	serum_cytokines	0.632	0.855	no	no	no	no	no	no	DM-DS
GDCA+blood	IL-17A	GDCA+blood+Hypotaurine+blood+L-Aspartic acid+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.632	0.855	no	no	no	no	no	no	DM-DS
GDCA+blood	IL-17A	GDCA+blood+Hypotaurine+blood+L-Histidine+blood-n3+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.632	0.855	no	no	no	no	no	no	DM-DS
P-hydroxyhippuric acid+urine	IL-17A	P-hydroxyhippuric acid+urine+Eotaxin-GM-CSF-IL-17A	Indirect	urine_cometabolism	serum_cytokines	0.436	0.855	no	no	no	no	no	no	DM-DS
acetic acid C2+blood	IL-17A	acetic acid C2+blood+d18:1-20:1-SM+blood-decanoic acid C10+blood-n3+blood-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.000193	0.855	up	dn	no	no	no	no	DM-DS
isovaleric acid iso-C5+blood	IL-17A	isovaleric acid iso-C5+blood+n3+blood-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.117	0.855	no	no	no	no	no	no	DM-DS
Clostridium	IL-17A	Clostridium-Small cell lung cancer+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-DS
Clostridium	IL-17A	Clostridium-Relaxin signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-DS
Clostridium	IL-17A	Clostridium-cAMP signaling pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-DS
Clostridium	IL-17A	Clostridium-Eotaxin-GM-CSF-IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-UDCA+stool+16:0/20:3-PC+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-UDCA+stool+18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-DS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-UDCA+stool+18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-18:0/20:3-PI+blood-18:3n3+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-18:0/18:1-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-16:1/18:1-PG+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-18:0/20:3-PI+blood+18:1/18:1-PC+blood+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-18:0/18:1-PE+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-18:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-18:1/22:6-PE+blood+n3+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-18:0/22:6-PI+blood+n3+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-16:0/18:0-PS+blood+n3+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-DS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-18:0/22:6-PE+blood+n3+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-17A	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood-Eotaxin-GM-CSF-IL-17A"	Indirect	Genus	serum_cytokines	0.852	0.855	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-17A	Butyricicoccus-18:2/20:4-PC+blood-DMG+blood-n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.852	0.855	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-17A	Butyricicoccus-18:2/20:4-PC+blood+20:4n6+blood+n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.852	0.855	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-17A	Butyricicoccus-18:2/20:4-PC+blood+EPA+blood+n3+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.852	0.855	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-17A	"Butyricicoccus+12,13-EPOME+blood-18:0/20:4-PI+blood+n3+blood-FGF basic+IL-17A"	Indirect	Genus	serum_cytokines	0.852	0.855	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-17A	Butyricicoccus-18:2/20:4-PC+blood+20:4n6+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.852	0.855	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-17A	Butyricicoccus-18:2/20:4-PC+blood+20:3/16:0-PC+blood-4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.852	0.855	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-17A	"Butyricicoccus+12,13-EPOME+blood+16:0/18:2-PI+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A"	Indirect	Genus	serum_cytokines	0.852	0.855	no	no	no	no	no	no	DM-DS
Butyricicoccus	IL-17A	"Butyricicoccus+12,13-EPOME+blood+18:0/18:1-PE+blood+4-hydroxy-3-methoxymandelic acid+urine+FGF basic+IL-17A"	Indirect	Genus	serum_cytokines	0.852	0.855	no	no	no	no	no	no	DM-DS
Blautia	Visfatin	Blautia-12-ketoDCA+stool+Indole-3-Acetic acid+urine+Visfatin	Indirect	Genus	DM-associated hormones	1.36E-05	0.0229	up	dn	dn	dn	no	up	DM-LS
Blautia	Visfatin	Blautia+14:0/20:4-PC+blood-GLCA+blood+Visfatin	Indirect	Genus	DM-associated hormones	1.36E-05	0.0229	up	dn	dn	dn	no	up	DM-LS
Parabacteroides	Visfatin	Parabacteroides-15-HETE+blood+Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	DM-LS
Dorea	Visfatin	Dorea-Lipid and atherosclerosis-14:0/20:4-PC+blood-GLCA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-LS
Dorea	Visfatin	Dorea-18:0/22:6-PE+blood+18:1/20:4-PE+blood+GLCA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-LS
Dorea	Visfatin	Dorea-Lipid and atherosclerosis-14:0/18:2-PC+blood-GLCA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-LS
Dorea	Visfatin	Dorea-18:0/22:6-PE+blood-18:2-LPA+blood+C-peptide-Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-LS
Dorea	Visfatin	Dorea-18:0/22:6-PE+blood+18:1/18:1-PE+blood+Indole-3-Acetic acid+urine+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-LS
Dorea	Visfatin	Dorea-Lipid and atherosclerosis+18:1/18:1-PE+blood+Indole-3-Acetic acid+urine+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-LS
Dorea	Visfatin	Dorea+d18:1-20:0-SM+blood+GPC+blood+Resistin+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-LS
Dorea	Visfatin	Dorea-18:0/22:6-PE+blood+IL-1ra+Resistin+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-LS
Dorea	Visfatin	Dorea-Lipid and atherosclerosis-18:0/22:6-PA+blood+18:1/18:2-PG+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-LS
Dorea	Visfatin	Dorea-Lipid and atherosclerosis+18:1+blood-18:1/18:2-PG+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-LS
Dorea	Visfatin	Dorea-18:0/22:6-PE+blood+IL-1ra+IL-8+Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	DM-LS
Faecalibacterium	Visfatin	Faecalibacterium+Leptin-Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	DM-LS
TUDCA+blood	Visfatin	TUDCA+blood+Eotaxin+IL-4-IL-8+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.0229	no	no	dn	dn	no	up	DM-LS
TUDCA+blood	Visfatin	TUDCA+blood+Eotaxin-GM-CSF+IL-8+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.0229	no	no	dn	dn	no	up	DM-LS
TUDCA+blood	Visfatin	TUDCA+blood+Eotaxin+IL-17A-IL-8+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.0229	no	no	dn	dn	no	up	DM-LS
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF+IL-8+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	DM-LS
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-4-IL-8+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	DM-LS
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-17A-IL-8+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	DM-LS
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood-n3+blood+Taurine+blood+Valine+blood+C-peptide-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	DM-LS
Bacteroides	Visfatin	Bacteroides-GCA+stool-Resistin+Visfatin	Indirect	Genus	DM-associated hormones	0.000267	0.0229	dn	dn	up	dn	no	up	DM-LS
Propionic acid+stool	Visfatin	Propionic acid+stool+16:0/18:0-PS+blood+18:1/18:2-PG+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.0229	dn	no	up	dn	no	up	DM-LS
Propionic acid+stool	Visfatin	Propionic acid+stool+18:0/18:0-PS+blood+18:1/18:2-PG+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.0229	dn	no	up	dn	no	up	DM-LS
Propionic acid+stool	Visfatin	Propionic acid+stool+16:0/18:0-PS+blood+Indole-3-Acetic acid+urine+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.0229	dn	no	up	dn	no	up	DM-LS
Propionic acid+stool	Visfatin	Propionic acid+stool-18:2-LPA+blood+C-peptide-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.0229	dn	no	up	dn	no	up	DM-LS
Propionic acid+stool	Visfatin	Propionic acid+stool+18:0/20:4-PI+blood+Resistin+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.0229	dn	no	up	dn	no	up	DM-LS
Propionic acid+stool	Visfatin	Propionic acid+stool-Glycine+blood-Resistin+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.0229	dn	no	up	dn	no	up	DM-LS
Propionic acid+stool	Visfatin	Propionic acid+stool-ACA+blood-Resistin+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.0229	dn	no	up	dn	no	up	DM-LS
[Ruminococcus]	Visfatin	[Ruminococcus]-15-HETE+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0679	0.0229	no	no	dn	dn	no	up	DM-LS
GUDCA+blood	Visfatin	GUDCA+blood+UDCA+blood+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.0229	no	no	dn	dn	no	up	DM-LS
UDCA+blood	Visfatin	UDCA+blood+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0939	0.0229	no	no	dn	dn	no	up	DM-LS
Acetic acid+stool	Visfatin	Acetic acid+stool-12-ketoDCA+blood+GLCA+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.0229	dn	no	no	dn	no	up	DM-LS
Acetic acid+stool	Visfatin	Acetic acid+stool+Butyric acid+stool-Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.0229	dn	no	no	dn	no	up	DM-LS
Acetic acid+stool	Visfatin	Acetic acid+stool+18:3n6+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.0229	dn	no	no	dn	no	up	DM-LS
Alistipes	Visfatin	Alistipes+12-ketoDCA+stool+Indole-3-Acetic acid+urine+Visfatin	Indirect	Genus	DM-associated hormones	0.0114	0.0229	no	up	no	dn	no	up	DM-LS
Alistipes	Visfatin	Alistipes+12-ketoDCA+blood+GLCA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0114	0.0229	no	up	no	dn	no	up	DM-LS
Butyricimonas	Visfatin	Butyricimonas-14:0/20:4-PC+blood-GLCA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.17	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-NF-kappa B signaling pathway-4-hydroxybenzoic acid+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-AGE-RAGE signaling pathway in diabetic complications-4-hydroxybenzoic acid+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-MAPK signaling pathway-Vascular smooth muscle contraction+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella+Arachidonic acid metabolism+Vascular smooth muscle contraction+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-Central carbon metabolism in cancer-Autoimmune thyroid disease-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-Central carbon metabolism in cancer-Allograft rejection-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-Insulin resistance+18:0-LPC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-NF-kappa B signaling pathway+18:0-LPC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-Central carbon metabolism in cancer-Viral myocarditis-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-Phosphatidylinositol signaling system-Viral myocarditis-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-Phosphatidylinositol signaling system-Cell adhesion molecules-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-Colorectal cancer+GLCA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-LCA+stool+GLCA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-18:0/20:4-PI+blood+Resistin+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-LCA+stool+Resistin+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-AGE-RAGE signaling pathway in diabetic complications+Resistin+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-Central carbon metabolism in cancer-Graft-versus-host disease-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-MAPK signaling pathway-Circadian entrainment+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella+Arachidonic acid metabolism+Circadian entrainment+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-MAPK signaling pathway-Endocrine and other factor-regulated calcium reabsorption+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-HDCA+stool-C-peptide-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella+20:1-LPA+blood+C-peptide-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
Collinsella	Visfatin	Collinsella-LCA+stool-C-peptide-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	DM-LS
total_blood_scfa+blood	Visfatin	total_blood_scfa+blood+TUDCA+blood+Eotaxin+IL-4-IL-8+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.168	0.0229	no	no	no	dn	no	up	DM-LS
total_blood_scfa+blood	Visfatin	total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-8+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.168	0.0229	no	no	no	dn	no	up	DM-LS
total_blood_scfa+blood	Visfatin	total_blood_scfa+blood+TUDCA+blood+Eotaxin+IL-17A-IL-8+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.168	0.0229	no	no	no	dn	no	up	DM-LS
[Eubacterium]	Visfatin	[Eubacterium]-Viral myocarditis-Visfatin	Indirect	Genus	DM-associated hormones	0.0692	0.0229	no	no	no	dn	no	up	DM-LS
LCA+stool	Visfatin	LCA+stool-C-peptide-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	DM-LS
LCA+stool	Visfatin	LCA+stool+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	DM-LS
LCA+stool	Visfatin	LCA+stool+GLCA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	DM-LS
Akkermansia	Visfatin	Akkermansia-4-hydroxybenzoic acid+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	DM-LS
Akkermansia	Visfatin	Akkermansia-18:1/18:2-PG+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	DM-LS
Bifidobacterium	Visfatin	Bifidobacterium+Chemical carcinogenesis - receptor activation+Visfatin	Indirect	Genus	DM-associated hormones	0.105	0.0229	no	dn	no	dn	no	up	DM-LS
3-Hydroxytyramine hydrochloride+urine	Visfatin	3-Hydroxytyramine hydrochloride+urine-Indole-3-Acetic acid+urine+Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.288	0.0229	no	no	no	dn	no	up	DM-LS
Ruminococcus	Visfatin	Ruminococcus+Type I diabetes mellitus-Visfatin	Indirect	Genus	DM-associated hormones	0.335	0.0229	no	no	no	dn	no	up	DM-LS
Ruminococcus	Visfatin	Ruminococcus+Natural killer cell mediated cytotoxicity-Visfatin	Indirect	Genus	DM-associated hormones	0.335	0.0229	no	no	no	dn	no	up	DM-LS
Ruminococcus	Visfatin	Ruminococcus+Endocytosis-Visfatin	Indirect	Genus	DM-associated hormones	0.335	0.0229	no	no	no	dn	no	up	DM-LS
Ruminococcus	Visfatin	Ruminococcus+Allograft rejection-Visfatin	Indirect	Genus	DM-associated hormones	0.335	0.0229	no	no	no	dn	no	up	DM-LS
Ruminococcus	Visfatin	Ruminococcus+Graft-versus-host disease-Visfatin	Indirect	Genus	DM-associated hormones	0.335	0.0229	no	no	no	dn	no	up	DM-LS
Ruminococcus	Visfatin	Ruminococcus+Cell adhesion molecules-Visfatin	Indirect	Genus	DM-associated hormones	0.335	0.0229	no	no	no	dn	no	up	DM-LS
Ruminococcus	Visfatin	Ruminococcus+Autoimmune thyroid disease-Visfatin	Indirect	Genus	DM-associated hormones	0.335	0.0229	no	no	no	dn	no	up	DM-LS
GCDCA+blood	Visfatin	GCDCA+blood+GUDCA+blood+UDCA+blood+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	DM-LS
GCDCA+blood	Visfatin	GCDCA+blood-T-a-MCA+blood-UDCA+blood+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	DM-LS
Succinivibrio	Visfatin	Succinivibrio-Phospholipase D signaling pathway+Chemical carcinogenesis - receptor activation+Visfatin	Indirect	Genus	DM-associated hormones	0.138	0.0229	no	no	no	dn	no	up	DM-LS
ACA+blood	Visfatin	ACA+blood-Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.0229	no	no	no	dn	no	up	DM-LS
DCA+stool	Visfatin	DCA+stool+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.0229	no	no	no	dn	no	up	DM-LS
2-hydroxyhippuric acid+urine	Visfatin	2-hydroxyhippuric acid+urine-3-Hydroxytyramine hydrochloride+urine-Indole-3-Acetic acid+urine+Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.215	0.0229	no	no	no	dn	no	up	DM-LS
2-hydroxyhippuric acid+urine	Visfatin	2-hydroxyhippuric acid+urine-3-Hydroxy-L-kynurenine+urine-Indole-3-Acetic acid+urine+Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.215	0.0229	no	no	no	dn	no	up	DM-LS
Butyric acid+stool	Visfatin	Butyric acid+stool-Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.102	0.0229	dn	no	no	dn	no	up	DM-LS
4-hydroxybenzoic acid+stool	Visfatin	4-hydroxybenzoic acid+stool-Visfatin	Direct	stool_cometabolism	DM-associated hormones	0.0536	0.0229	no	dn	no	dn	no	up	DM-LS
GCA+blood	Visfatin	GCA+blood+FGF basic+IL-17A-IL-8+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.0229	no	no	no	dn	no	up	DM-LS
GCA+blood	Visfatin	GCA+blood+GUDCA+blood+UDCA+blood+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.0229	no	no	no	dn	no	up	DM-LS
ACA+stool	Visfatin	ACA+stool+Sarcosine+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.0229	no	no	no	dn	no	up	DM-LS
ACA+stool	Visfatin	ACA+stool-L-Citrulline+blood-Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.0229	no	no	no	dn	no	up	DM-LS
ACA+stool	Visfatin	ACA+stool+GPC+blood+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.0229	no	no	no	dn	no	up	DM-LS
ACA+stool	Visfatin	ACA+stool-GCA+stool-Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.0229	no	no	no	dn	no	up	DM-LS
ACA+stool	Visfatin	ACA+stool+16:0-LPC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.0229	no	no	no	dn	no	up	DM-LS
CDCA+blood	Visfatin	CDCA+blood+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.0229	no	no	no	dn	no	up	DM-LS
capric acid C6+blood	Visfatin	capric acid C6+blood-Sarcosine+blood+Leptin-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.433	0.0229	no	no	no	dn	no	up	DM-LS
capric acid C6+blood	Visfatin	capric acid C6+blood-CDCA+blood+Leptin-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.433	0.0229	no	no	no	dn	no	up	DM-LS
capric acid C6+blood	Visfatin	capric acid C6+blood+L-Tryptophan+blood-Leptin-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.433	0.0229	no	no	no	dn	no	up	DM-LS
Pyramidobacter	Visfatin	"Pyramidobacter+Parathyroid hormone synthesis, secretion and action+Visfatin"	Indirect	Genus	DM-associated hormones	0.45	0.0229	no	no	no	dn	no	up	DM-LS
Prevotella	Visfatin	Prevotella+Regulation of lipolysis in adipocytes+Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	DM-LS
Prevotella	Visfatin	Prevotella+18:0-LPC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	DM-LS
Prevotella	Visfatin	Prevotella+Endocrine resistance+Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	DM-LS
Prevotella	Visfatin	Prevotella+Chemical carcinogenesis - receptor activation+Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	DM-LS
Prevotella	Visfatin	Prevotella+Inflammatory mediator regulation of TRP channels+Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	DM-LS
Prevotella	Visfatin	Prevotella+Endocrine and other factor-regulated calcium reabsorption+Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	DM-LS
TCA+blood	Visfatin	TCA+blood+FGF basic+IL-17A-IL-8+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.339	0.0229	no	no	no	dn	no	up	DM-LS
iso-DCA+blood	Visfatin	iso-DCA+blood+Valine+blood+C-peptide-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.0229	no	no	no	dn	no	up	DM-LS
iso-DCA+blood	Visfatin	iso-DCA+blood+L-Leucine+blood+C-peptide-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.0229	no	no	no	dn	no	up	DM-LS
HCA+stool	Visfatin	HCA+stool-GPC+blood+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	DM-LS
HCA+stool	Visfatin	HCA+stool+24:0+blood-GLCA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	DM-LS
HCA+stool	Visfatin	HCA+stool+UDCA+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	DM-LS
HCA+stool	Visfatin	HCA+stool+CDCA+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	DM-LS
HCA+stool	Visfatin	HCA+stool-L-Homocystine+blood-Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	DM-LS
HCA+stool	Visfatin	HCA+stool+18:0-LPA+blood+C-peptide-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	DM-LS
HCA+stool	Visfatin	HCA+stool-18:1+blood-18:1/18:2-PG+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	DM-LS
Roseburia	Visfatin	Roseburia+16:0/18:0-PS+blood+Indole-3-Acetic acid+urine+Visfatin	Indirect	Genus	DM-associated hormones	0.495	0.0229	no	no	no	dn	no	up	DM-LS
Roseburia	Visfatin	Roseburia-Valine+blood+C-peptide-Visfatin	Indirect	Genus	DM-associated hormones	0.495	0.0229	no	no	no	dn	no	up	DM-LS
Roseburia	Visfatin	Roseburia+HCA+blood+Leptin-Visfatin	Indirect	Genus	DM-associated hormones	0.495	0.0229	no	no	no	dn	no	up	DM-LS
Roseburia	Visfatin	Roseburia+16:0/18:0-PS+blood+18:1/18:2-PG+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.495	0.0229	no	no	no	dn	no	up	DM-LS
Roseburia	Visfatin	Roseburia-16:0-LPC+blood+18:0-LPC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.495	0.0229	no	no	no	dn	no	up	DM-LS
12-ketoDCA+stool	Visfatin	12-ketoDCA+stool+Indole-3-Acetic acid+urine+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.0229	no	no	no	dn	no	up	DM-LS
GLCA+blood	Visfatin	GLCA+blood+Visfatin	Direct	serum_bileacids	DM-associated hormones	0.319	0.0229	no	no	no	dn	no	up	DM-LS
L-Tryptophan+stool	Visfatin	L-Tryptophan+stool+L-Tryptophan+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.0229	no	no	no	dn	no	up	DM-LS
L-Tryptophan+stool	Visfatin	L-Tryptophan+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.0229	no	no	no	dn	no	up	DM-LS
L-Tryptophan+stool	Visfatin	L-Tryptophan+stool-18:0-LPA+blood+C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.0229	no	no	no	dn	no	up	DM-LS
L-Tryptophan+stool	Visfatin	L-Tryptophan+stool+L-Tyrosine+blood+C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.0229	no	no	no	dn	no	up	DM-LS
CA+blood	Visfatin	CA+blood+HCA+blood+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.0229	no	no	no	dn	no	up	DM-LS
CA+blood	Visfatin	CA+blood+CDCA+blood+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.0229	no	no	no	dn	no	up	DM-LS
CA+blood	Visfatin	CA+blood+UDCA+blood+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.0229	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	Visfatin	L-Phenylalanine+stool+L-Methionine+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.0229	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	Visfatin	L-Phenylalanine+stool+L-Tryptophan+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.0229	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	Visfatin	L-Phenylalanine+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.0229	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	Visfatin	L-Phenylalanine+stool+16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.0229	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	Visfatin	L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.0229	no	no	no	dn	no	up	DM-LS
butyric acid C4+blood	Visfatin	butyric acid C4+blood+isobutyric acid C4+blood+isovaleric acid iso-C5+blood-UDCA+blood+Leptin-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.407	0.0229	no	no	no	dn	no	up	DM-LS
GCA+stool	Visfatin	GCA+stool-Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.0229	no	no	no	dn	no	up	DM-LS
T-a-MCA+blood	Visfatin	T-a-MCA+blood-UDCA+blood+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.478	0.0229	no	no	no	dn	no	up	DM-LS
Coprococcus	Visfatin	Coprococcus-Endocrine and other factor-regulated calcium reabsorption+Visfatin	Indirect	Genus	DM-associated hormones	0.612	0.0229	no	no	no	dn	no	up	DM-LS
Coprococcus	Visfatin	Coprococcus-Vascular smooth muscle contraction+Visfatin	Indirect	Genus	DM-associated hormones	0.612	0.0229	no	no	no	dn	no	up	DM-LS
Coprococcus	Visfatin	Coprococcus-Circadian entrainment+Visfatin	Indirect	Genus	DM-associated hormones	0.612	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+urine	Visfatin	Indole-3-Acetic acid+urine+Visfatin	Direct	urine_cometabolism	DM-associated hormones	0.657	0.0229	no	no	no	dn	no	up	DM-LS
Oscillospira	Visfatin	Oscillospira-4-hydroxybenzoic acid+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.62	0.0229	no	no	no	dn	no	up	DM-LS
HCA+blood	Visfatin	HCA+blood+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.544	0.0229	no	no	no	dn	no	up	DM-LS
iso-LCA+stool	Visfatin	iso-LCA+stool+LCA+stool+GLCA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-LS
iso-LCA+stool	Visfatin	iso-LCA+stool+18:0/20:4-PI+blood+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-LS
iso-LCA+stool	Visfatin	iso-LCA+stool+LCA+stool+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-LS
iso-LCA+stool	Visfatin	iso-LCA+stool-Glycine+blood-Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-LS
iso-LCA+stool	Visfatin	iso-LCA+stool-CDCA+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-LS
iso-LCA+stool	Visfatin	iso-LCA+stool-UDCA+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-LS
iso-LCA+stool	Visfatin	iso-LCA+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-LS
iso-LCA+stool	Visfatin	iso-LCA+stool-Sarcosine+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-LS
iso-LCA+stool	Visfatin	iso-LCA+stool+LCA+stool-C-peptide-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	DM-LS
2-methyl-butyric acid m-C4+blood	Visfatin	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+L-Leucine+blood+C-peptide-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.262	0.0229	no	no	no	dn	no	up	DM-LS
2-methyl-butyric acid m-C4+blood	Visfatin	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+L-Isoleucine+blood+C-peptide-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.262	0.0229	no	no	no	dn	no	up	DM-LS
2-methyl-butyric acid m-C4+blood	Visfatin	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+Valine+blood+C-peptide-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.262	0.0229	no	no	no	dn	no	up	DM-LS
2-methyl-butyric acid m-C4+blood	Visfatin	2-methyl-butyric acid m-C4+blood-CA+blood+CDCA+blood+Leptin-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.262	0.0229	no	no	no	dn	no	up	DM-LS
2-methyl-butyric acid m-C4+blood	Visfatin	2-methyl-butyric acid m-C4+blood-CA+blood+HCA+blood+Leptin-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.262	0.0229	no	no	no	dn	no	up	DM-LS
2-methyl-butyric acid m-C4+blood	Visfatin	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+L-Tryptophan+blood-Leptin-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.262	0.0229	no	no	no	dn	no	up	DM-LS
2-methyl-butyric acid m-C4+blood	Visfatin	2-methyl-butyric acid m-C4+blood-CA+blood+UDCA+blood+Leptin-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.262	0.0229	no	no	no	dn	no	up	DM-LS
DCA+blood	Visfatin	DCA+blood+UDCA+blood+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.0229	no	no	no	dn	no	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Visfatin	3-(3-Hydroxyphenyl)propanoic acid+stool-16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.0229	no	no	no	dn	no	up	DM-LS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	Visfatin	"3-(3,4-dihydroxyphenyl)propionic acid+urine+3-Hydroxy-L-kynurenine+urine-Indole-3-Acetic acid+urine+Visfatin"	Indirect	urine_cometabolism	DM-associated hormones	0.0125	0.0229	up	up	no	dn	no	up	DM-LS
nutriCA+blood	Visfatin	nutriCA+blood+UDCA+blood+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.726	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-IL-1ra+IL-8+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-IL-1ra+Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Tyrosine+stool-18:1/18:1-PE+blood+Indole-3-Acetic acid+urine+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Tyrosine+stool+16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-18:0-LPA+blood+C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Tryptophan+stool-18:0-LPA+blood+C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Tryptophan+stool+L-Tyrosine+blood+C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Tyrosine+stool+L-Tyrosine+blood+C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+L-Methionine+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Tyrosine+stool+L-Methionine+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Tryptophan+stool+L-Tryptophan+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+L-Tryptophan+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Tyrosine+stool+L-Tryptophan+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Tryptophan+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Tyrosine+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-Sarcosine+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	DM-LS
TCA+stool	Visfatin	TCA+stool+18:1/18:1-PC+blood+C-peptide-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.0229	no	no	no	dn	no	up	DM-LS
TCA+stool	Visfatin	TCA+stool+16:0/20:3-PC+blood+C-peptide-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.0229	no	no	no	dn	no	up	DM-LS
TCA+stool	Visfatin	TCA+stool+18:1/18:1-PC+blood-GLCA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.0229	no	no	no	dn	no	up	DM-LS
TCA+stool	Visfatin	TCA+stool+16:0/20:3-PC+blood-GLCA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.0229	no	no	no	dn	no	up	DM-LS
TCA+stool	Visfatin	TCA+stool-18:0/20:4-PI+blood+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.0229	no	no	no	dn	no	up	DM-LS
HDCA+stool	Visfatin	HDCA+stool-C-peptide-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.0229	no	no	no	dn	no	up	DM-LS
Lachnospira	Visfatin	Lachnospira-Adherens junction+Viral myocarditis-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-LS
Lachnospira	Visfatin	Lachnospira+18:1/18:1-PC+blood-GLCA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-LS
Lachnospira	Visfatin	Lachnospira+16:0/20:3-PC+blood-GLCA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-LS
Lachnospira	Visfatin	Lachnospira+18:1/18:1-PC+blood+C-peptide-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-LS
Lachnospira	Visfatin	Lachnospira+Choline+blood+C-peptide-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-LS
Lachnospira	Visfatin	Lachnospira+16:0/20:3-PC+blood+C-peptide-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	DM-LS
Fusobacterium	Visfatin	Fusobacterium+16:0/20:3-PC+blood-GLCA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.628	0.0229	no	no	no	dn	no	up	DM-LS
Fusobacterium	Visfatin	Fusobacterium+18:1/18:1-PC+blood-GLCA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.628	0.0229	no	no	no	dn	no	up	DM-LS
Fusobacterium	Visfatin	Fusobacterium+16:0/20:3-PC+blood+C-peptide-Visfatin	Indirect	Genus	DM-associated hormones	0.628	0.0229	no	no	no	dn	no	up	DM-LS
Fusobacterium	Visfatin	Fusobacterium+18:1/18:1-PC+blood+C-peptide-Visfatin	Indirect	Genus	DM-associated hormones	0.628	0.0229	no	no	no	dn	no	up	DM-LS
Fusobacterium	Visfatin	Fusobacterium-DCA+stool+Resistin+Visfatin	Indirect	Genus	DM-associated hormones	0.628	0.0229	no	no	no	dn	no	up	DM-LS
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+isovaleric acid iso-C5+blood-UDCA+blood+Leptin-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	DM-LS
GCDCA+stool	Visfatin	GCDCA+stool+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.0229	no	dn	no	dn	no	up	DM-LS
GCDCA+stool	Visfatin	GCDCA+stool-Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.0229	no	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool+L-Tyrosine+stool+16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+L-Tryptophan+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool+L-Tyrosine+stool+L-Tryptophan+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool+L-Phenylalanine+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool+L-Tyrosine+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool-Acetic acid+stool+18:3n6+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+L-Methionine+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool+L-Tyrosine+stool+L-Methionine+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool-Acetic acid+stool+Butyric acid+stool-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool+L-Tyrosine+stool+L-Tyrosine+blood+C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool-Propionic acid+stool-18:2-LPA+blood+C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:0-PS+blood+Indole-3-Acetic acid+urine+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool+L-Tyrosine+stool-18:1/18:1-PE+blood+Indole-3-Acetic acid+urine+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool-Acetic acid+stool-12-ketoDCA+blood+GLCA+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool-Propionic acid+stool+18:0/18:0-PS+blood+18:1/18:2-PG+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:0-PS+blood+18:1/18:2-PG+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool-Propionic acid+stool-ACA+blood-Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool-Propionic acid+stool-Glycine+blood-Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool-Propionic acid+stool+18:0/20:4-PI+blood+Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	DM-LS
Odoribacter	Visfatin	Odoribacter+IL-8+Visfatin	Indirect	Genus	DM-associated hormones	0.798	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+L-Tyrosine+stool-18:1/18:1-PE+blood+Indole-3-Acetic acid+urine+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool-UDCA+stool+CDCA+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+L-Tyrosine+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool-UDCA+stool+18:3n6+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+L-Tryptophan+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+L-Phenylalanine+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool-UDCA+stool-L-Homocystine+blood-Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool-UDCA+stool+UDCA+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool-nutriCA+stool+UDCA+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool-Sarcosine+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+L-Tyrosine+stool+L-Methionine+blood-Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+L-Phenylalanine+stool+L-Methionine+blood-Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool-nutriCA+stool+HCA+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+L-Tyrosine+stool+L-Tryptophan+blood-Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+L-Tryptophan+stool+L-Tryptophan+blood-Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+L-Phenylalanine+stool+L-Tryptophan+blood-Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+L-Tyrosine+stool+16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool-UDCA+stool-16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+L-Phenylalanine+stool+16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool-IL-1ra+Resistin+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool-IL-1ra+IL-8+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+L-Tryptophan+stool-18:0-LPA+blood+C-peptide-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool-18:0-LPA+blood+C-peptide-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+L-Tyrosine+stool+L-Tyrosine+blood+C-peptide-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+L-Tryptophan+stool+L-Tyrosine+blood+C-peptide-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	DM-LS
2-hydroxyphenylacetic acid+urine	Visfatin	2-hydroxyphenylacetic acid+urine-3-Hydroxytyramine hydrochloride+urine-Indole-3-Acetic acid+urine+Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.763	0.0229	no	no	no	dn	no	up	DM-LS
Lachnobacterium	Visfatin	Lachnobacterium+T-a-MCA+blood-UDCA+blood+Leptin-Visfatin	Indirect	Genus	DM-associated hormones	0.867	0.0229	no	no	no	dn	no	up	DM-LS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool+L-Tyrosine+stool-18:1/18:1-PE+blood+Indole-3-Acetic acid+urine+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool+L-Tyrosine+stool+L-Tyrosine+blood+C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool-UDCA+stool-16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool+L-Tyrosine+stool+16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool-UDCA+stool+CDCA+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool-UDCA+stool+18:3n6+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool+L-Tyrosine+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool+L-Tyrosine+stool+L-Tryptophan+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool-UDCA+stool-L-Homocystine+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool+L-Tyrosine+stool+L-Methionine+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool-UDCA+stool+UDCA+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool-nutriCA+stool+UDCA+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool-nutriCA+stool+HCA+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	DM-LS
Anaerostipes	Visfatin	Anaerostipes+15-HETE+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.568	0.0229	no	no	no	dn	no	up	DM-LS
TUDCA+stool	Visfatin	TUDCA+stool-UDCA+stool+UDCA+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.0229	no	no	no	dn	no	up	DM-LS
TUDCA+stool	Visfatin	TUDCA+stool-UDCA+stool+18:3n6+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.0229	no	no	no	dn	no	up	DM-LS
TUDCA+stool	Visfatin	TUDCA+stool-UDCA+stool-L-Homocystine+blood-Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.0229	no	no	no	dn	no	up	DM-LS
TUDCA+stool	Visfatin	TUDCA+stool-UDCA+stool+CDCA+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.0229	no	no	no	dn	no	up	DM-LS
TUDCA+stool	Visfatin	TUDCA+stool-UDCA+stool-16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool-IL-1ra+Resistin+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool-IL-1ra+IL-8+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+L-Phenylalanine+stool+16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool-UDCA+stool-16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+L-Tyrosine+stool+16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool-UDCA+stool+CDCA+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool-Sarcosine+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+L-Phenylalanine+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool-UDCA+stool+18:3n6+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+L-Tyrosine+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+L-Tryptophan+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+L-Phenylalanine+stool+L-Methionine+blood-Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+L-Tyrosine+stool+L-Methionine+blood-Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool-UDCA+stool-L-Homocystine+blood-Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+L-Phenylalanine+stool+L-Tryptophan+blood-Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+L-Tyrosine+stool+L-Tryptophan+blood-Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+L-Tryptophan+stool+L-Tryptophan+blood-Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool-UDCA+stool+UDCA+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool-nutriCA+stool+UDCA+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool-nutriCA+stool+HCA+blood+Leptin-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+L-Tyrosine+stool+L-Tyrosine+blood+C-peptide-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+L-Tryptophan+stool+L-Tyrosine+blood+C-peptide-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool-18:0-LPA+blood+C-peptide-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+L-Tryptophan+stool-18:0-LPA+blood+C-peptide-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+L-Tyrosine+stool-18:1/18:1-PE+blood+Indole-3-Acetic acid+urine+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	DM-LS
Paraprevotella	Visfatin	Paraprevotella+Betaine+blood-Leptin-Visfatin	Indirect	Genus	DM-associated hormones	0.118	0.0229	no	no	no	dn	no	up	DM-LS
Paraprevotella	Visfatin	Paraprevotella+Glutathione metabolism+Circadian entrainment+Visfatin	Indirect	Genus	DM-associated hormones	0.118	0.0229	no	no	no	dn	no	up	DM-LS
Paraprevotella	Visfatin	Paraprevotella+Arachidonic acid metabolism+Circadian entrainment+Visfatin	Indirect	Genus	DM-associated hormones	0.118	0.0229	no	no	no	dn	no	up	DM-LS
Paraprevotella	Visfatin	Paraprevotella+Glutathione metabolism+Endocrine and other factor-regulated calcium reabsorption+Visfatin	Indirect	Genus	DM-associated hormones	0.118	0.0229	no	no	no	dn	no	up	DM-LS
Paraprevotella	Visfatin	Paraprevotella-18:0/22:6-PA+blood+18:1/18:2-PG+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.118	0.0229	no	no	no	dn	no	up	DM-LS
Paraprevotella	Visfatin	Paraprevotella+Glutathione metabolism+Regulation of lipolysis in adipocytes+Visfatin	Indirect	Genus	DM-associated hormones	0.118	0.0229	no	no	no	dn	no	up	DM-LS
Paraprevotella	Visfatin	Paraprevotella+Glutathione metabolism+Vascular smooth muscle contraction+Visfatin	Indirect	Genus	DM-associated hormones	0.118	0.0229	no	no	no	dn	no	up	DM-LS
Paraprevotella	Visfatin	Paraprevotella+Arachidonic acid metabolism+Vascular smooth muscle contraction+Visfatin	Indirect	Genus	DM-associated hormones	0.118	0.0229	no	no	no	dn	no	up	DM-LS
iso-LCA+blood	Visfatin	iso-LCA+blood-Sarcosine+blood+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.507	0.0229	no	no	no	dn	no	up	DM-LS
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool-18:0-LPA+blood+C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	DM-LS
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool-Sarcosine+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	DM-LS
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	DM-LS
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool-IL-1ra+Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	DM-LS
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool-IL-1ra+IL-8+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	DM-LS
Gemmiger	Visfatin	Gemmiger-GCA+stool-Resistin+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-LS
Gemmiger	Visfatin	Gemmiger+L-Tyrosine+blood+C-peptide-Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	DM-LS
GDCA+stool	Visfatin	GDCA+stool-Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	DM-LS
Methanobrevibacter	Visfatin	Methanobrevibacter+18:0-LPC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.629	0.0229	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool-18:1/18:1-PE+blood+Indole-3-Acetic acid+urine+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool+16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool+L-Tyrosine+blood+C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool+L-Methionine+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool+L-Tryptophan+blood-Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool-18:3n6+blood+Leptin-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	DM-LS
CDCA+stool	Visfatin	CDCA+stool+HCA+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.0229	no	no	no	dn	no	up	DM-LS
CDCA+stool	Visfatin	CDCA+stool+18:3n6+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.0229	no	no	no	dn	no	up	DM-LS
CDCA+stool	Visfatin	CDCA+stool-LCA+stool+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.0229	no	no	no	dn	no	up	DM-LS
CDCA+stool	Visfatin	CDCA+stool-LCA+stool-C-peptide-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.0229	no	no	no	dn	no	up	DM-LS
CDCA+stool	Visfatin	CDCA+stool-HDCA+stool-C-peptide-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.0229	no	no	no	dn	no	up	DM-LS
CDCA+stool	Visfatin	CDCA+stool+18:0-LPA+blood+C-peptide-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.0229	no	no	no	dn	no	up	DM-LS
CDCA+stool	Visfatin	CDCA+stool-LCA+stool+GLCA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.0229	no	no	no	dn	no	up	DM-LS
CA+stool	Visfatin	CA+stool-HDCA+stool-C-peptide-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-LS
CA+stool	Visfatin	CA+stool-LCA+stool-C-peptide-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-LS
CA+stool	Visfatin	CA+stool+CDCA+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-LS
CA+stool	Visfatin	CA+stool+18:3n6+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-LS
CA+stool	Visfatin	CA+stool-LCA+stool+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-LS
CA+stool	Visfatin	CA+stool-18:0/20:4-PI+blood+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-LS
CA+stool	Visfatin	CA+stool-LCA+stool+GLCA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	DM-LS
Slackia	Visfatin	Slackia-15-HETE+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.94	0.0229	no	no	no	dn	no	up	DM-LS
HDCA+blood	Visfatin	HDCA+blood-Sarcosine+blood+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.0229	no	no	no	dn	no	up	DM-LS
UDCA+stool	Visfatin	UDCA+stool+UDCA+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.0229	no	no	no	dn	no	up	DM-LS
UDCA+stool	Visfatin	UDCA+stool+18:3n6+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.0229	no	no	no	dn	no	up	DM-LS
UDCA+stool	Visfatin	UDCA+stool-L-Homocystine+blood-Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.0229	no	no	no	dn	no	up	DM-LS
UDCA+stool	Visfatin	UDCA+stool+CDCA+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.0229	no	no	no	dn	no	up	DM-LS
UDCA+stool	Visfatin	UDCA+stool-16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.0229	no	no	no	dn	no	up	DM-LS
TDCA+stool	Visfatin	TDCA+stool+UDCA+stool+UDCA+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.0229	no	no	no	dn	no	up	DM-LS
TDCA+stool	Visfatin	TDCA+stool+UDCA+stool+18:3n6+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.0229	no	no	no	dn	no	up	DM-LS
TDCA+stool	Visfatin	TDCA+stool+UDCA+stool-L-Homocystine+blood-Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.0229	no	no	no	dn	no	up	DM-LS
TDCA+stool	Visfatin	TDCA+stool+UDCA+stool+CDCA+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.0229	no	no	no	dn	no	up	DM-LS
TDCA+stool	Visfatin	TDCA+stool+UDCA+stool-16:0/18:0-PC+blood+18:0-LPC+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.0229	no	no	no	dn	no	up	DM-LS
nutriCA+stool	Visfatin	nutriCA+stool+HCA+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.0229	no	no	no	dn	no	up	DM-LS
nutriCA+stool	Visfatin	nutriCA+stool+UDCA+blood+Leptin-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.0229	no	no	no	dn	no	up	DM-LS
GDCA+blood	Visfatin	GDCA+blood+iso-LCA+blood-Sarcosine+blood+Leptin-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.0229	no	no	no	dn	no	up	DM-LS
acetic acid C2+blood	Visfatin	acetic acid C2+blood-Sarcosine+blood+Leptin-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.000193	0.0229	up	dn	no	dn	no	up	DM-LS
isovaleric acid iso-C5+blood	Visfatin	isovaleric acid iso-C5+blood-UDCA+blood+Leptin-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.117	0.0229	no	no	no	dn	no	up	DM-LS
Adlercreutzia	Visfatin	Adlercreutzia+18:0-LPC+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.548	0.0229	no	no	no	dn	no	up	DM-LS
Clostridium	Visfatin	Clostridium+20:1-LPA+blood+C-peptide-Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	DM-LS
Clostridium	Visfatin	Clostridium+cGMP-PKG signaling pathway+Endocytosis-Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	DM-LS
Clostridium	Visfatin	Clostridium+CDCA+blood+Leptin-Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	DM-LS
Clostridium	Visfatin	Clostridium-Butyric acid+stool-Leptin-Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	DM-LS
 Clostridium	Visfatin	Clostridium+Butyric acid+stool-Leptin-Visfatin	Indirect	Genus	DM-associated hormones	NA	0.0229	NA	NA	NA	dn	no	up	DM-LS
Clostridium	Visfatin	Clostridium-Butyric acid+stool-Leptin-Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	DM-LS
 Clostridium	Visfatin	Clostridium+Butyric acid+stool-Leptin-Visfatin	Indirect	Genus	DM-associated hormones	NA	0.0229	NA	NA	NA	dn	no	up	DM-LS
Clostridium	Visfatin	Clostridium-14:0/16:0-PC+blood-GLCA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	DM-LS
Clostridium	Visfatin	Clostridium-14:0/20:4-PC+blood-GLCA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	DM-LS
Clostridium	Visfatin	Clostridium-14:0/18:2-PC+blood-GLCA+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	DM-LS
T-¦Á-MCA+stool	Visfatin	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+C-peptide-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.0229	no	no	no	dn	no	up	DM-LS
T-¦Á-MCA+stool	Visfatin	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+C-peptide-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.0229	no	no	no	dn	no	up	DM-LS
T-¦Á-MCA+stool	Visfatin	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood-GLCA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.0229	no	no	no	dn	no	up	DM-LS
T-¦Á-MCA+stool	Visfatin	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood-GLCA+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.0229	no	no	no	dn	no	up	DM-LS
T-¦Á-MCA+stool	Visfatin	T-¦Á-MCA+stool-TCA+stool-18:0/20:4-PI+blood+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.0229	no	no	no	dn	no	up	DM-LS
12-ketoDCA+blood	Visfatin	12-ketoDCA+blood+GLCA+blood+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.0229	no	no	no	dn	no	up	DM-LS
Butyricicoccus	Visfatin	Butyricicoccus+Allograft rejection-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	DM-LS
Butyricicoccus	Visfatin	Butyricicoccus+Viral myocarditis-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	DM-LS
Butyricicoccus	Visfatin	Butyricicoccus+Cell adhesion molecules-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	DM-LS
Butyricicoccus	Visfatin	Butyricicoccus+Type I diabetes mellitus-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	DM-LS
Butyricicoccus	Visfatin	Butyricicoccus+Graft-versus-host disease-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	DM-LS
Butyricicoccus	Visfatin	Butyricicoccus+Natural killer cell mediated cytotoxicity-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	DM-LS
Butyricicoccus	Visfatin	Butyricicoccus+Autoimmune thyroid disease-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	DM-LS
3-Hydroxy-L-kynurenine+urine	Visfatin	3-Hydroxy-L-kynurenine+urine-Indole-3-Acetic acid+urine+Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.401	0.0229	no	no	no	dn	no	up	DM-LS
Blautia	PAI-1	Blautia-16:0/22:6-PC+blood+16:1/16:1-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	1.36E-05	5.10E-05	up	dn	dn	up	up	up	DM-LS
Blautia	PAI-1	Blautia-16:0/18:2-PC+blood+16:1/16:1-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	1.36E-05	5.10E-05	up	dn	dn	up	up	up	DM-LS
Blautia	PAI-1	Blautia+d18:1-16:1-SM+blood-L-Methionine+blood+PAI-1	Indirect	Genus	DM-associated hormones	1.36E-05	5.10E-05	up	dn	dn	up	up	up	DM-LS
Blautia	PAI-1	Blautia+14:0/20:4-PC+blood-L-Methionine+blood+PAI-1	Indirect	Genus	DM-associated hormones	1.36E-05	5.10E-05	up	dn	dn	up	up	up	DM-LS
Blautia	PAI-1	Blautia+d18:1-16:1-SM+blood-L-Isoleucine+blood+PAI-1	Indirect	Genus	DM-associated hormones	1.36E-05	5.10E-05	up	dn	dn	up	up	up	DM-LS
Blautia	PAI-1	Blautia+d18:1-16:1-SM+blood-L-Tryptophan+blood+PAI-1	Indirect	Genus	DM-associated hormones	1.36E-05	5.10E-05	up	dn	dn	up	up	up	DM-LS
Blautia	PAI-1	Blautia-L-Ornithine+blood+L-Tryptophan+blood+PAI-1	Indirect	Genus	DM-associated hormones	1.36E-05	5.10E-05	up	dn	dn	up	up	up	DM-LS
Blautia	PAI-1	Blautia-L-Ornithine+blood+L-Proline+blood+PAI-1	Indirect	Genus	DM-associated hormones	1.36E-05	5.10E-05	up	dn	dn	up	up	up	DM-LS
Blautia	PAI-1	Blautia-iso-LCA+blood+L-Proline+blood+PAI-1	Indirect	Genus	DM-associated hormones	1.36E-05	5.10E-05	up	dn	dn	up	up	up	DM-LS
Blautia	PAI-1	Blautia-12-ketoDCA+stool-L-Alanine+blood+PAI-1	Indirect	Genus	DM-associated hormones	1.36E-05	5.10E-05	up	dn	dn	up	up	up	DM-LS
Blautia	PAI-1	Blautia+d18:0-24:1-SM+blood+L-Alanine+blood+PAI-1	Indirect	Genus	DM-associated hormones	1.36E-05	5.10E-05	up	dn	dn	up	up	up	DM-LS
Blautia	PAI-1	Blautia+14:0/20:4-PC+blood-Ethanolamine+blood+PAI-1	Indirect	Genus	DM-associated hormones	1.36E-05	5.10E-05	up	dn	dn	up	up	up	DM-LS
Blautia	PAI-1	Blautia-LCA+blood-Homovanillic acid+urine-PAI-1	Indirect	Genus	DM-associated hormones	1.36E-05	5.10E-05	up	dn	dn	up	up	up	DM-LS
Blautia	PAI-1	Blautia-iso-LCA+blood-Homovanillic acid+urine-PAI-1	Indirect	Genus	DM-associated hormones	1.36E-05	5.10E-05	up	dn	dn	up	up	up	DM-LS
Parabacteroides	PAI-1	Parabacteroides-TCA+stool-PAI-1	Indirect	Genus	DM-associated hormones	4.19E-05	5.10E-05	no	up	up	up	up	up	DM-LS
Parabacteroides	PAI-1	Parabacteroides+L-Tyrosine+blood+PAI-1	Indirect	Genus	DM-associated hormones	4.19E-05	5.10E-05	no	up	up	up	up	up	DM-LS
Parabacteroides	PAI-1	Parabacteroides+Ethanolamine+blood+PAI-1	Indirect	Genus	DM-associated hormones	4.19E-05	5.10E-05	no	up	up	up	up	up	DM-LS
Parabacteroides	PAI-1	Parabacteroides+L-Isoleucine+blood+PAI-1	Indirect	Genus	DM-associated hormones	4.19E-05	5.10E-05	no	up	up	up	up	up	DM-LS
Dorea	PAI-1	Dorea+PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.00362	5.10E-05	up	no	dn	up	up	up	DM-LS
Faecalibacterium	PAI-1	Faecalibacterium-16:1/16:1-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.0039	5.10E-05	no	dn	dn	up	up	up	DM-LS
TUDCA+blood	PAI-1	TUDCA+blood+Eotaxin-GM-CSF+IL-1b-PDGF-bb+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0282	5.10E-05	no	no	dn	up	up	up	DM-LS
TUDCA+blood	PAI-1	TUDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0282	5.10E-05	no	no	dn	up	up	up	DM-LS
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood-n3+blood-L-Tryptophan+urine+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	DM-LS
Bacteroides	PAI-1	"Bacteroides-9,10-EPOME+blood+L-Citrulline+blood+PAI-1"	Indirect	Genus	DM-associated hormones	0.000267	5.10E-05	dn	dn	up	up	up	up	DM-LS
Bacteroides	PAI-1	Bacteroides+Cytokine-cytokine receptor interaction-Chronic myeloid leukemia+PAI-1	Indirect	Genus	DM-associated hormones	0.000267	5.10E-05	dn	dn	up	up	up	up	DM-LS
Bacteroides	PAI-1	Bacteroides-GCA+stool+TCA+stool-PAI-1	Indirect	Genus	DM-associated hormones	0.000267	5.10E-05	dn	dn	up	up	up	up	DM-LS
Bacteroides	PAI-1	Bacteroides+n3+blood-L-Tryptophan+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.000267	5.10E-05	dn	dn	up	up	up	up	DM-LS
Bacteroides	PAI-1	Bacteroides+22:6n3+blood-L-Tryptophan+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.000267	5.10E-05	dn	dn	up	up	up	up	DM-LS
Bacteroides	PAI-1	Bacteroides+Cytokine-cytokine receptor interaction+Hematopoietic cell lineage-PAI-1	Indirect	Genus	DM-associated hormones	0.000267	5.10E-05	dn	dn	up	up	up	up	DM-LS
Bacteroides	PAI-1	Bacteroides+Cytokine-cytokine receptor interaction-Prostate cancer+PAI-1	Indirect	Genus	DM-associated hormones	0.000267	5.10E-05	dn	dn	up	up	up	up	DM-LS
Bacteroides	PAI-1	Bacteroides+Cytokine-cytokine receptor interaction-L-Methionine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.000267	5.10E-05	dn	dn	up	up	up	up	DM-LS
Bacteroides	PAI-1	Bacteroides-8-HETE+blood+AA+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.000267	5.10E-05	dn	dn	up	up	up	up	DM-LS
Bacteroides	PAI-1	Bacteroides+22:6n3+blood+L-Isoleucine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.000267	5.10E-05	dn	dn	up	up	up	up	DM-LS
Bacteroides	PAI-1	Bacteroides-GCA+stool+Homovanillic acid+urine-PAI-1	Indirect	Genus	DM-associated hormones	0.000267	5.10E-05	dn	dn	up	up	up	up	DM-LS
Propionic acid+stool	PAI-1	Propionic acid+stool-TCA+stool-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.0436	5.10E-05	dn	no	up	up	up	up	DM-LS
5-Hydroxyindole-3-acetic Acid+urine	PAI-1	5-Hydroxyindole-3-acetic Acid+urine-DL-Indole-3-lactic acid+urine+L-Phenylalanine+urine+L-Tyrosine+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.0405	5.10E-05	no	dn	dn	up	up	up	DM-LS
5-Hydroxyindole-3-acetic Acid+urine	PAI-1	5-Hydroxyindole-3-acetic Acid+urine-DL-Indole-3-lactic acid+urine+L-Phenylalanine+urine+L-Tryptophan+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.0405	5.10E-05	no	dn	dn	up	up	up	DM-LS
[Ruminococcus]	PAI-1	[Ruminococcus]-TCA+stool-PAI-1	Indirect	Genus	DM-associated hormones	0.0679	5.10E-05	no	no	dn	up	up	up	DM-LS
GUDCA+blood	PAI-1	GUDCA+blood-LCA+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0766	5.10E-05	no	no	dn	up	up	up	DM-LS
Acetic acid+stool	PAI-1	Acetic acid+stool+AA+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.0656	5.10E-05	dn	no	no	up	up	up	DM-LS
Acetic acid+stool	PAI-1	Acetic acid+stool+Butyric acid+stool+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.0656	5.10E-05	dn	no	no	up	up	up	DM-LS
Alistipes	PAI-1	Alistipes-HIF-1 signaling pathway+L-Tyrosine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-LS
Alistipes	PAI-1	Alistipes+12-ketoDCA+blood-20:4-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-LS
Alistipes	PAI-1	Alistipes+12-ketoDCA+stool-L-Alanine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-LS
Alistipes	PAI-1	Alistipes-L-Arginine+blood+L-Citrulline+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	DM-LS
Butyricimonas	PAI-1	Butyricimonas+L-Lysine+blood+L-Tryptophan+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.17	5.10E-05	no	no	no	up	up	up	DM-LS
Butyricimonas	PAI-1	Butyricimonas+L-Histidine+blood+L-Tryptophan+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.17	5.10E-05	no	no	no	up	up	up	DM-LS
Butyricimonas	PAI-1	Butyricimonas+L-Lysine+blood+L-Tyrosine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.17	5.10E-05	no	no	no	up	up	up	DM-LS
Butyricimonas	PAI-1	Butyricimonas+L-Histidine+blood+L-Tyrosine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.17	5.10E-05	no	no	no	up	up	up	DM-LS
Butyricimonas	PAI-1	Butyricimonas-d18:1-24:1-SM+blood-L-Tyrosine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.17	5.10E-05	no	no	no	up	up	up	DM-LS
Butyricimonas	PAI-1	Butyricimonas-14:0/20:4-PC+blood-Ethanolamine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.17	5.10E-05	no	no	no	up	up	up	DM-LS
Butyricimonas	PAI-1	Butyricimonas-14:0/20:4-PC+blood-L-Methionine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.17	5.10E-05	no	no	no	up	up	up	DM-LS
Butyricimonas	PAI-1	Butyricimonas+L-Histidine+blood+L-Methionine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.17	5.10E-05	no	no	no	up	up	up	DM-LS
Butyricimonas	PAI-1	Butyricimonas+L-Histidine+blood+L-Isoleucine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.17	5.10E-05	no	no	no	up	up	up	DM-LS
Butyricimonas	PAI-1	Butyricimonas-d18:0-24:1-SM+blood+L-Alanine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.17	5.10E-05	no	no	no	up	up	up	DM-LS
Butyricimonas	PAI-1	Butyricimonas-Prion disease-Chronic myeloid leukemia+PAI-1	Indirect	Genus	DM-associated hormones	0.17	5.10E-05	no	no	no	up	up	up	DM-LS
Collinsella	PAI-1	Collinsella-Prostate cancer+PAI-1	Indirect	Genus	DM-associated hormones	0.128	5.10E-05	no	no	no	up	up	up	DM-LS
total_blood_scfa+blood	PAI-1	total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-1b-PDGF-bb+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.168	5.10E-05	no	no	no	up	up	up	DM-LS
total_blood_scfa+blood	PAI-1	total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.168	5.10E-05	no	no	no	up	up	up	DM-LS
[Eubacterium]	PAI-1	[Eubacterium]-Viral myocarditis-L-Citrulline+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.0692	5.10E-05	no	no	no	up	up	up	DM-LS
[Eubacterium]	PAI-1	[Eubacterium]-Phagosome-L-Citrulline+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.0692	5.10E-05	no	no	no	up	up	up	DM-LS
[Eubacterium]	PAI-1	[Eubacterium]-Fluid shear stress and atherosclerosis-L-Tryptophan+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.0692	5.10E-05	no	no	no	up	up	up	DM-LS
[Eubacterium]	PAI-1	[Eubacterium]-Viral myocarditis-L-Tyrosine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.0692	5.10E-05	no	no	no	up	up	up	DM-LS
[Eubacterium]	PAI-1	[Eubacterium]-Salmonella infection-L-Tyrosine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.0692	5.10E-05	no	no	no	up	up	up	DM-LS
[Eubacterium]	PAI-1	[Eubacterium]-Salmonella infection-Chronic myeloid leukemia+PAI-1	Indirect	Genus	DM-associated hormones	0.0692	5.10E-05	no	no	no	up	up	up	DM-LS
[Eubacterium]	PAI-1	[Eubacterium]-Fluid shear stress and atherosclerosis-L-Tyrosine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.0692	5.10E-05	no	no	no	up	up	up	DM-LS
[Eubacterium]	PAI-1	[Eubacterium]-Phagosome-L-Tyrosine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.0692	5.10E-05	no	no	no	up	up	up	DM-LS
LCA+stool	PAI-1	LCA+stool-TCA+stool-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.314	5.10E-05	no	no	no	up	up	up	DM-LS
Akkermansia	PAI-1	Akkermansia-L-Alanine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium+Glycine+blood+L-Glutamine+blood+L-Tryptophan+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium+Chemical carcinogenesis - receptor activation-L-Glutamine+blood+L-Tryptophan+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium+d18:1-18:1-SM+blood-L-Ornithine+blood+L-Tryptophan+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium+Glycine+blood+L-Asparagine+blood+L-Tryptophan+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium+Chemical carcinogenesis - receptor activation+Small cell lung cancer+L-Alanine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium+Chemical carcinogenesis - receptor activation+Small cell lung cancer+Ethanolamine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	"Bifidobacterium+d18:1-18:1-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine+L-Tyrosine+urine+PAI-1"	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium-18:2/20:4-PC+blood+20:0-LPC+blood+L-Citrulline+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium+Glycine+blood+L-Arginine+blood+L-Citrulline+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium+Glycine+blood+L-Asparagine+blood+L-Citrulline+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium+Glycine+blood+L-Glutamine+blood+L-Isoleucine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium+Chemical carcinogenesis - receptor activation-L-Glutamine+blood+L-Isoleucine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium+Glycine+blood+L-Asparagine+blood+L-Isoleucine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium+Chemical carcinogenesis - receptor activation-UDCA+stool+Homovanillic acid+urine-PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium+d18:1-18:1-SM+blood-GDCA+blood-Homovanillic acid+urine-PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium+d18:1-18:1-SM+blood-L-Ornithine+blood+L-Proline+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium+Glycine+blood+L-Asparagine+blood+L-Methionine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium-18:2/20:4-PC+blood+20:0/20:5-PC+blood+AA+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
Bifidobacterium	PAI-1	Bifidobacterium+Chemical carcinogenesis - receptor activation+16:0/16:0-PC+blood+16:1/16:1-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	DM-LS
3-Hydroxytyramine hydrochloride+urine	PAI-1	3-Hydroxytyramine hydrochloride+urine+L-Tyrosine+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.288	5.10E-05	no	no	no	up	up	up	DM-LS
Ruminococcus	PAI-1	Ruminococcus+Cell adhesion molecules-L-Tyrosine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.335	5.10E-05	no	no	no	up	up	up	DM-LS
Ruminococcus	PAI-1	Ruminococcus-L-Homocystine+blood-Homovanillic acid+urine-PAI-1	Indirect	Genus	DM-associated hormones	0.335	5.10E-05	no	no	no	up	up	up	DM-LS
Ruminococcus	PAI-1	Ruminococcus+Type I diabetes mellitus-L-Citrulline+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.335	5.10E-05	no	no	no	up	up	up	DM-LS
Ruminococcus	PAI-1	Ruminococcus+Allograft rejection-L-Citrulline+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.335	5.10E-05	no	no	no	up	up	up	DM-LS
Ruminococcus	PAI-1	Ruminococcus+Graft-versus-host disease-L-Citrulline+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.335	5.10E-05	no	no	no	up	up	up	DM-LS
Ruminococcus	PAI-1	Ruminococcus+Phagosome-L-Citrulline+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.335	5.10E-05	no	no	no	up	up	up	DM-LS
Ruminococcus	PAI-1	Ruminococcus+Cell adhesion molecules-L-Citrulline+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.335	5.10E-05	no	no	no	up	up	up	DM-LS
Ruminococcus	PAI-1	Ruminococcus+Autoimmune thyroid disease-L-Citrulline+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.335	5.10E-05	no	no	no	up	up	up	DM-LS
Ruminococcus	PAI-1	Ruminococcus+22:6n3+blood-L-Tryptophan+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.335	5.10E-05	no	no	no	up	up	up	DM-LS
Ruminococcus	PAI-1	Ruminococcus+22:6n3+blood+L-Isoleucine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.335	5.10E-05	no	no	no	up	up	up	DM-LS
Ruminococcus	PAI-1	Ruminococcus+Phagosome-L-Tyrosine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.335	5.10E-05	no	no	no	up	up	up	DM-LS
GCDCA+blood	PAI-1	GCDCA+blood+GUDCA+blood-LCA+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.31	5.10E-05	no	no	no	up	up	up	DM-LS
Succinivibrio	PAI-1	Succinivibrio-L-Tyrosine+stool+L-Tyrosine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.138	5.10E-05	no	no	no	up	up	up	DM-LS
Succinivibrio	PAI-1	Succinivibrio-L-Phenylalanine+stool+L-Tyrosine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.138	5.10E-05	no	no	no	up	up	up	DM-LS
Succinivibrio	PAI-1	Succinivibrio-L-Tyrosine+stool+L-Tryptophan+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.138	5.10E-05	no	no	no	up	up	up	DM-LS
Succinivibrio	PAI-1	Succinivibrio-L-Phenylalanine+stool+L-Tryptophan+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.138	5.10E-05	no	no	no	up	up	up	DM-LS
Succinivibrio	PAI-1	Succinivibrio-L-Tyrosine+stool+L-Methionine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.138	5.10E-05	no	no	no	up	up	up	DM-LS
Succinivibrio	PAI-1	Succinivibrio-L-Phenylalanine+stool+L-Methionine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.138	5.10E-05	no	no	no	up	up	up	DM-LS
Succinivibrio	PAI-1	Succinivibrio-Phospholipase D signaling pathway+PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.138	5.10E-05	no	no	no	up	up	up	DM-LS
Succinivibrio	PAI-1	Succinivibrio-Phospholipase D signaling pathway-Hematopoietic cell lineage-PAI-1	Indirect	Genus	DM-associated hormones	0.138	5.10E-05	no	no	no	up	up	up	DM-LS
Succinivibrio	PAI-1	Succinivibrio-Phospholipase D signaling pathway-Toxoplasmosis-PAI-1	Indirect	Genus	DM-associated hormones	0.138	5.10E-05	no	no	no	up	up	up	DM-LS
Succinivibrio	PAI-1	Succinivibrio-Phospholipase D signaling pathway+AA+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.138	5.10E-05	no	no	no	up	up	up	DM-LS
Succinivibrio	PAI-1	Succinivibrio-Phospholipase D signaling pathway+Chronic myeloid leukemia+PAI-1	Indirect	Genus	DM-associated hormones	0.138	5.10E-05	no	no	no	up	up	up	DM-LS
ACA+blood	PAI-1	ACA+blood-DL-methionine sulfoxide+blood+L-Isoleucine+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.338	5.10E-05	no	no	no	up	up	up	DM-LS
ACA+blood	PAI-1	ACA+blood-DL-methionine sulfoxide+blood+Ethanolamine+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.338	5.10E-05	no	no	no	up	up	up	DM-LS
ACA+blood	PAI-1	ACA+blood-DL-methionine sulfoxide+blood+L-Tyrosine+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.338	5.10E-05	no	no	no	up	up	up	DM-LS
ACA+blood	PAI-1	ACA+blood-DL-methionine sulfoxide+blood+L-Methionine+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.338	5.10E-05	no	no	no	up	up	up	DM-LS
DCA+stool	PAI-1	DCA+stool-TCA+stool-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.195	5.10E-05	no	no	no	up	up	up	DM-LS
2-hydroxyhippuric acid+urine	PAI-1	2-hydroxyhippuric acid+urine-L-Tyrosine+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.215	5.10E-05	no	no	no	up	up	up	DM-LS
2-hydroxyhippuric acid+urine	PAI-1	2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.215	5.10E-05	no	no	no	up	up	up	DM-LS
Butyric acid+stool	PAI-1	Butyric acid+stool+PAI-1	Direct	stool_scfa	DM-associated hormones	0.102	5.10E-05	dn	no	no	up	up	up	DM-LS
4-hydroxybenzoic acid+stool	PAI-1	4-hydroxybenzoic acid+stool-LCA+blood-Homovanillic acid+urine-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.0536	5.10E-05	no	dn	no	up	up	up	DM-LS
4-hydroxybenzoic acid+stool	PAI-1	4-hydroxybenzoic acid+stool+L-Asparagine+blood+L-Methionine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.0536	5.10E-05	no	dn	no	up	up	up	DM-LS
4-hydroxybenzoic acid+stool	PAI-1	4-hydroxybenzoic acid+stool+L-Asparagine+blood+L-Citrulline+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.0536	5.10E-05	no	dn	no	up	up	up	DM-LS
4-hydroxybenzoic acid+stool	PAI-1	4-hydroxybenzoic acid+stool+L-Asparagine+blood+L-Isoleucine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.0536	5.10E-05	no	dn	no	up	up	up	DM-LS
4-hydroxybenzoic acid+stool	PAI-1	4-hydroxybenzoic acid+stool+L-Asparagine+blood+L-Tryptophan+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.0536	5.10E-05	no	dn	no	up	up	up	DM-LS
4-hydroxybenzoic acid+stool	PAI-1	4-hydroxybenzoic acid+stool+CDCA+stool+TCA+stool-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.0536	5.10E-05	no	dn	no	up	up	up	DM-LS
4-hydroxybenzoic acid+stool	PAI-1	4-hydroxybenzoic acid+stool+18:2-LPE+blood-L-Tyrosine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.0536	5.10E-05	no	dn	no	up	up	up	DM-LS
4-hydroxybenzoic acid+stool	PAI-1	"4-hydroxybenzoic acid+stool-12,13-EPOME+blood+Hypotaurine+blood+PAI-1"	Indirect	stool_cometabolism	DM-associated hormones	0.0536	5.10E-05	no	dn	no	up	up	up	DM-LS
GCA+blood	PAI-1	GCA+blood+GDCA+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.16	5.10E-05	no	no	no	up	up	up	DM-LS
ACA+stool	PAI-1	ACA+stool-L-Citrulline+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.417	5.10E-05	no	no	no	up	up	up	DM-LS
CDCA+blood	PAI-1	CDCA+blood-L-Tryptophan+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.506	5.10E-05	no	no	no	up	up	up	DM-LS
CDCA+blood	PAI-1	CDCA+blood-L-Methionine+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.506	5.10E-05	no	no	no	up	up	up	DM-LS
capric acid C6+blood	PAI-1	capric acid C6+blood+L-Tryptophan+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.433	5.10E-05	no	no	no	up	up	up	DM-LS
capric acid C6+blood	PAI-1	capric acid C6+blood-L-Alanine+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.433	5.10E-05	no	no	no	up	up	up	DM-LS
Pyramidobacter	PAI-1	Pyramidobacter-Homovanillic acid+urine-PAI-1	Indirect	Genus	DM-associated hormones	0.45	5.10E-05	no	no	no	up	up	up	DM-LS
Pyramidobacter	PAI-1	Pyramidobacter+L-Tryptophan+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.45	5.10E-05	no	no	no	up	up	up	DM-LS
Pyramidobacter	PAI-1	Pyramidobacter+L-Tyrosine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.45	5.10E-05	no	no	no	up	up	up	DM-LS
Pyramidobacter	PAI-1	Pyramidobacter+Ethanolamine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.45	5.10E-05	no	no	no	up	up	up	DM-LS
Pyramidobacter	PAI-1	Pyramidobacter+Prostate cancer+PAI-1	Indirect	Genus	DM-associated hormones	0.45	5.10E-05	no	no	no	up	up	up	DM-LS
Prevotella	PAI-1	Prevotella+PAI-1	Direct	Genus	DM-associated hormones	0.287	5.10E-05	no	no	no	up	up	up	DM-LS
TCA+blood	PAI-1	TCA+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-1b-PDGF-bb+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.339	5.10E-05	no	no	no	up	up	up	DM-LS
TCA+blood	PAI-1	TCA+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.339	5.10E-05	no	no	no	up	up	up	DM-LS
iso-DCA+blood	PAI-1	iso-DCA+blood+L-Leucine+blood+L-Methionine+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.38	5.10E-05	no	no	no	up	up	up	DM-LS
iso-DCA+blood	PAI-1	iso-DCA+blood+L-Lysine+blood+L-Tyrosine+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.38	5.10E-05	no	no	no	up	up	up	DM-LS
iso-DCA+blood	PAI-1	iso-DCA+blood+L-Leucine+blood+L-Tyrosine+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.38	5.10E-05	no	no	no	up	up	up	DM-LS
iso-DCA+blood	PAI-1	iso-DCA+blood+L-Phenylalanine+blood+L-Tyrosine+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.38	5.10E-05	no	no	no	up	up	up	DM-LS
iso-DCA+blood	PAI-1	iso-DCA+blood+L-Lysine+blood+L-Tryptophan+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.38	5.10E-05	no	no	no	up	up	up	DM-LS
iso-DCA+blood	PAI-1	iso-DCA+blood+L-Leucine+blood+L-Tryptophan+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.38	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool-Cysteine+blood+L-Isoleucine+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool-18:0/20:4-PC+blood+20:4-LPC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool-18:1+blood-20:4-LPC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool-Cysteine+blood-PDGF-bb+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool-18:1+blood-PDGF-bb+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool-16:0/16:0-PC+blood+16:1/16:1-PC+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool-Cysteine+blood+L-Tyrosine+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool-18:1+blood-L-Tryptophan+urine+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool-iso-LCA+stool-TCA+stool-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool+CDCA+blood-L-Tryptophan+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool-Cysteine+blood+L-Tryptophan+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool+CDCA+blood-L-Methionine+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool-Cysteine+blood+L-Methionine+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool+UDCA+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool-LCA+blood-Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool-L-Homocystine+blood-Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool-18:1+blood-L-Proline+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool+24:0+blood-Hypotaurine+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+stool	PAI-1	HCA+stool-18:0/20:5-PC+blood+AA+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	DM-LS
Roseburia	PAI-1	Roseburia-16:0-LPC+blood+PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	DM-LS
Roseburia	PAI-1	Roseburia-18:2n6c+blood-20:4-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	DM-LS
Roseburia	PAI-1	Roseburia+HCA+blood+L-Proline+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	DM-LS
Roseburia	PAI-1	Roseburia-20:1+blood+L-Citrulline+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	DM-LS
Roseburia	PAI-1	Roseburia+CDCA+stool+TCA+stool-PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	DM-LS
Roseburia	PAI-1	Roseburia+CA+stool+TCA+stool-PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	DM-LS
Roseburia	PAI-1	Roseburia-16:0-LPC+blood+18:0-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	DM-LS
12-ketoDCA+stool	PAI-1	12-ketoDCA+stool-L-Alanine+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.505	5.10E-05	no	no	no	up	up	up	DM-LS
4-Hydroxyphenylacetic acid+urine	PAI-1	4-Hydroxyphenylacetic acid+urine-5-Hydroxyindole-3-acetic Acid+urine-DL-Indole-3-lactic acid+urine+L-Phenylalanine+urine+L-Tyrosine+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.0321	5.10E-05	up	up	no	up	up	up	DM-LS
4-Hydroxyphenylacetic acid+urine	PAI-1	4-Hydroxyphenylacetic acid+urine-5-Hydroxyindole-3-acetic Acid+urine-DL-Indole-3-lactic acid+urine+L-Phenylalanine+urine+L-Tryptophan+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.0321	5.10E-05	up	up	no	up	up	up	DM-LS
GLCA+blood	PAI-1	GLCA+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.319	5.10E-05	no	no	no	up	up	up	DM-LS
L-Tryptophan+stool	PAI-1	L-Tryptophan+stool+L-Tryptophan+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.557	5.10E-05	no	no	no	up	up	up	DM-LS
L-Tryptophan+stool	PAI-1	L-Tryptophan+stool+L-Tyrosine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.557	5.10E-05	no	no	no	up	up	up	DM-LS
CA+blood	PAI-1	CA+blood-Cysteine+blood+L-Tyrosine+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	DM-LS
CA+blood	PAI-1	CA+blood+HCA+blood+L-Proline+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	DM-LS
CA+blood	PAI-1	CA+blood-capric acid C6+blood+L-Tryptophan+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	DM-LS
CA+blood	PAI-1	CA+blood-Cysteine+blood+L-Tryptophan+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	DM-LS
CA+blood	PAI-1	CA+blood-L-Glutamine+blood+L-Tryptophan+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	DM-LS
CA+blood	PAI-1	CA+blood+CDCA+blood-L-Tryptophan+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	DM-LS
CA+blood	PAI-1	CA+blood-Cysteine+blood+L-Isoleucine+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	DM-LS
CA+blood	PAI-1	CA+blood-L-Glutamine+blood+L-Isoleucine+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	DM-LS
CA+blood	PAI-1	CA+blood-Cysteine+blood+L-Methionine+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	DM-LS
CA+blood	PAI-1	CA+blood+CDCA+blood-L-Methionine+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	DM-LS
CA+blood	PAI-1	CA+blood-Cysteine+blood-PDGF-bb+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	DM-LS
CA+blood	PAI-1	CA+blood-capric acid C6+blood-L-Alanine+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	DM-LS
L-Phenylalanine+stool	PAI-1	L-Phenylalanine+stool+L-Methionine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.398	5.10E-05	no	no	no	up	up	up	DM-LS
L-Phenylalanine+stool	PAI-1	L-Phenylalanine+stool+L-Tyrosine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.398	5.10E-05	no	no	no	up	up	up	DM-LS
L-Phenylalanine+stool	PAI-1	L-Phenylalanine+stool+L-Tryptophan+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.398	5.10E-05	no	no	no	up	up	up	DM-LS
butyric acid C4+blood	PAI-1	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood+5-Hydroxyindole-3-acetic Acid+urine-DL-Indole-3-lactic acid+urine+L-Phenylalanine+urine+L-Tyrosine+urine+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.407	5.10E-05	no	no	no	up	up	up	DM-LS
butyric acid C4+blood	PAI-1	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b-PDGF-bb+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.407	5.10E-05	no	no	no	up	up	up	DM-LS
butyric acid C4+blood	PAI-1	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13-PDGF-bb+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.407	5.10E-05	no	no	no	up	up	up	DM-LS
butyric acid C4+blood	PAI-1	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood+5-Hydroxyindole-3-acetic Acid+urine-DL-Indole-3-lactic acid+urine+L-Phenylalanine+urine+L-Tryptophan+urine+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.407	5.10E-05	no	no	no	up	up	up	DM-LS
GCA+stool	PAI-1	GCA+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0809	5.10E-05	no	no	no	up	up	up	DM-LS
GCA+stool	PAI-1	GCA+stool+TCA+stool-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0809	5.10E-05	no	no	no	up	up	up	DM-LS
T-a-MCA+blood	PAI-1	T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b-PDGF-bb+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.478	5.10E-05	no	no	no	up	up	up	DM-LS
T-a-MCA+blood	PAI-1	T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13-PDGF-bb+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.478	5.10E-05	no	no	no	up	up	up	DM-LS
Coprococcus	PAI-1	Coprococcus+Butyric acid+stool+PAI-1	Indirect	Genus	DM-associated hormones	0.612	5.10E-05	no	no	no	up	up	up	DM-LS
Coprococcus	PAI-1	Coprococcus-TCA+stool-PAI-1	Indirect	Genus	DM-associated hormones	0.612	5.10E-05	no	no	no	up	up	up	DM-LS
Oscillospira	PAI-1	Oscillospira-Adrenergic signaling in cardiomyocytes-Toxoplasmosis-PAI-1	Indirect	Genus	DM-associated hormones	0.62	5.10E-05	no	no	no	up	up	up	DM-LS
Oscillospira	PAI-1	Oscillospira-CDCA+stool+TCA+stool-PAI-1	Indirect	Genus	DM-associated hormones	0.62	5.10E-05	no	no	no	up	up	up	DM-LS
Oscillospira	PAI-1	Oscillospira+Peroxisome-L-Alanine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.62	5.10E-05	no	no	no	up	up	up	DM-LS
Oscillospira	PAI-1	Oscillospira-18:2-LPE+blood-L-Tyrosine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.62	5.10E-05	no	no	no	up	up	up	DM-LS
Oscillospira	PAI-1	Oscillospira+L-Phenylalanine+blood+L-Tyrosine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.62	5.10E-05	no	no	no	up	up	up	DM-LS
Oscillospira	PAI-1	Oscillospira-Adrenergic signaling in cardiomyocytes-L-Isoleucine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.62	5.10E-05	no	no	no	up	up	up	DM-LS
HCA+blood	PAI-1	HCA+blood+L-Proline+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.544	5.10E-05	no	no	no	up	up	up	DM-LS
iso-LCA+stool	PAI-1	iso-LCA+stool-TCA+stool-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.72	5.10E-05	no	no	no	up	up	up	DM-LS
2-methyl-butyric acid m-C4+blood	PAI-1	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+L-Isoleucine+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.262	5.10E-05	no	no	no	up	up	up	DM-LS
2-methyl-butyric acid m-C4+blood	PAI-1	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+L-Tryptophan+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.262	5.10E-05	no	no	no	up	up	up	DM-LS
DCA+blood	PAI-1	DCA+blood-L-Glutamine+blood+L-Tryptophan+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.122	5.10E-05	no	no	no	up	up	up	DM-LS
DCA+blood	PAI-1	DCA+blood-L-Glutamine+blood+L-Isoleucine+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.122	5.10E-05	no	no	no	up	up	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool-LCA+blood-Homovanillic acid+urine-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool+UDCA+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool-iso-LCA+blood-Homovanillic acid+urine-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool-16:0/18:0-PC+blood+18:0-LPC+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/20:5-PC+blood+AA+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool-20:0/20:5-PC+blood+AA+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool-iso-LCA+blood+L-Proline+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool-18:3/18:2-PC+blood-Ethanolamine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool-18:3/18:2-PC+blood-L-Isoleucine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2n6c+blood-20:4-LPC+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	DM-LS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	PAI-1	"3-(3,4-dihydroxyphenyl)propionic acid+urine+L-Tyrosine+urine+PAI-1"	Indirect	urine_cometabolism	DM-associated hormones	0.0125	5.10E-05	up	up	no	up	up	up	DM-LS
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+L-Methionine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	DM-LS
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool+L-Tyrosine+stool+L-Methionine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	DM-LS
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool+L-Tryptophan+stool+L-Tryptophan+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	DM-LS
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+L-Tryptophan+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	DM-LS
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool+L-Tyrosine+stool+L-Tryptophan+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	DM-LS
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool+L-Tryptophan+stool+L-Tyrosine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	DM-LS
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+L-Tyrosine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	DM-LS
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool+L-Tyrosine+stool+L-Tyrosine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	DM-LS
TCA+stool	PAI-1	TCA+stool-PAI-1	Direct	stool_bileacids	DM-associated hormones	0.458	5.10E-05	no	no	no	up	up	up	DM-LS
HDCA+stool	PAI-1	HDCA+stool-20:2/18:0-PC+blood+L-Alanine+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.176	5.10E-05	no	no	no	up	up	up	DM-LS
HDCA+stool	PAI-1	HDCA+stool-18:0/20:3-PC+blood+L-Alanine+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.176	5.10E-05	no	no	no	up	up	up	DM-LS
HDCA+stool	PAI-1	"HDCA+stool+12,13-EPOME+blood+Hypotaurine+blood+PAI-1"	Indirect	stool_bileacids	DM-associated hormones	0.176	5.10E-05	no	no	no	up	up	up	DM-LS
HDCA+stool	PAI-1	HDCA+stool-16:0-LPC+blood+PDGF-bb+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.176	5.10E-05	no	no	no	up	up	up	DM-LS
HDCA+stool	PAI-1	HDCA+stool-18:1-LPC+blood-L-Tyrosine+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.176	5.10E-05	no	no	no	up	up	up	DM-LS
HDCA+stool	PAI-1	HDCA+stool+LCA+blood-Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.176	5.10E-05	no	no	no	up	up	up	DM-LS
HDCA+stool	PAI-1	HDCA+stool-20:2/18:0-PC+blood+Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.176	5.10E-05	no	no	no	up	up	up	DM-LS
HDCA+stool	PAI-1	HDCA+stool-18:0/20:3-PC+blood+Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.176	5.10E-05	no	no	no	up	up	up	DM-LS
HDCA+stool	PAI-1	HDCA+stool+iso-LCA+stool-TCA+stool-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.176	5.10E-05	no	no	no	up	up	up	DM-LS
HDCA+stool	PAI-1	HDCA+stool+LCA+stool-TCA+stool-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.176	5.10E-05	no	no	no	up	up	up	DM-LS
HDCA+stool	PAI-1	HDCA+stool-16:0-LPC+blood+18:0-LPC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.176	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnospira	PAI-1	Lachnospira-d18:1-16:1-SM+blood-L-Methionine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnospira	PAI-1	Lachnospira-Adherens junction-Chronic myeloid leukemia+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnospira	PAI-1	Lachnospira-d18:1-16:1-SM+blood-L-Tryptophan+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnospira	PAI-1	Lachnospira+8-HETE+blood+AA+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnospira	PAI-1	Lachnospira+18:0/20:5-PC+blood+AA+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnospira	PAI-1	Lachnospira+20:0/20:5-PC+blood+AA+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnospira	PAI-1	Lachnospira-d18:0-24:1-SM+blood+L-Alanine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnospira	PAI-1	Lachnospira+Choline+blood+Ethanolamine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnospira	PAI-1	Lachnospira+16:0/20:4-PC+blood+20:4-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnospira	PAI-1	Lachnospira+18:0/20:4-PC+blood+20:4-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnospira	PAI-1	Lachnospira-Adherens junction-Prostate cancer+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnospira	PAI-1	Lachnospira-Adherens junction+Hematopoietic cell lineage-PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnospira	PAI-1	Lachnospira+Choline+blood+L-Tyrosine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnospira	PAI-1	Lachnospira+16:0/18:2-PC+blood+16:1/16:1-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnospira	PAI-1	Lachnospira-d18:1-16:1-SM+blood-L-Isoleucine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnospira	PAI-1	Lachnospira+Choline+blood+L-Isoleucine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	DM-LS
Fusobacterium	PAI-1	Fusobacterium-DCA+stool-TCA+stool-PAI-1	Indirect	Genus	DM-associated hormones	0.628	5.10E-05	no	no	no	up	up	up	DM-LS
isobutyric acid C4+blood	PAI-1	isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b-PDGF-bb+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0151	5.10E-05	up	up	no	up	up	up	DM-LS
isobutyric acid C4+blood	PAI-1	isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13-PDGF-bb+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0151	5.10E-05	up	up	no	up	up	up	DM-LS
isobutyric acid C4+blood	PAI-1	isobutyric acid C4+blood+MUFA%+blood+5-Hydroxyindole-3-acetic Acid+urine-DL-Indole-3-lactic acid+urine+L-Phenylalanine+urine+L-Tryptophan+urine+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0151	5.10E-05	up	up	no	up	up	up	DM-LS
isobutyric acid C4+blood	PAI-1	isobutyric acid C4+blood+MUFA%+blood+5-Hydroxyindole-3-acetic Acid+urine-DL-Indole-3-lactic acid+urine+L-Phenylalanine+urine+L-Tyrosine+urine+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0151	5.10E-05	up	up	no	up	up	up	DM-LS
GCDCA+stool	PAI-1	GCDCA+stool+TCA+stool-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0471	5.10E-05	no	dn	no	up	up	up	DM-LS
GCDCA+stool	PAI-1	GCDCA+stool-L-Isoleucine+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0471	5.10E-05	no	dn	no	up	up	up	DM-LS
5-Hydroxytryptamine+stool	PAI-1	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+L-Tryptophan+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.00862	5.10E-05	dn	dn	no	up	up	up	DM-LS
5-Hydroxytryptamine+stool	PAI-1	5-Hydroxytryptamine+stool+L-Tyrosine+stool+L-Tryptophan+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.00862	5.10E-05	dn	dn	no	up	up	up	DM-LS
5-Hydroxytryptamine+stool	PAI-1	5-Hydroxytryptamine+stool-Propionic acid+stool-TCA+stool-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.00862	5.10E-05	dn	dn	no	up	up	up	DM-LS
5-Hydroxytryptamine+stool	PAI-1	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+L-Methionine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.00862	5.10E-05	dn	dn	no	up	up	up	DM-LS
5-Hydroxytryptamine+stool	PAI-1	5-Hydroxytryptamine+stool+L-Tyrosine+stool+L-Methionine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.00862	5.10E-05	dn	dn	no	up	up	up	DM-LS
5-Hydroxytryptamine+stool	PAI-1	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+L-Tyrosine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.00862	5.10E-05	dn	dn	no	up	up	up	DM-LS
5-Hydroxytryptamine+stool	PAI-1	5-Hydroxytryptamine+stool+L-Tyrosine+stool+L-Tyrosine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.00862	5.10E-05	dn	dn	no	up	up	up	DM-LS
5-Hydroxytryptamine+stool	PAI-1	5-Hydroxytryptamine+stool-Acetic acid+stool+Butyric acid+stool+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.00862	5.10E-05	dn	dn	no	up	up	up	DM-LS
5-Hydroxytryptamine+stool	PAI-1	5-Hydroxytryptamine+stool-Acetic acid+stool+AA+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.00862	5.10E-05	dn	dn	no	up	up	up	DM-LS
Odoribacter	PAI-1	Odoribacter-Homovanillic acid+urine-PAI-1	Indirect	Genus	DM-associated hormones	0.798	5.10E-05	no	no	no	up	up	up	DM-LS
Odoribacter	PAI-1	Odoribacter+Ethanolamine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.798	5.10E-05	no	no	no	up	up	up	DM-LS
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool-UDCA+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	DM-LS
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool+L-Tyrosine+stool+L-Methionine+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	DM-LS
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool+L-Phenylalanine+stool+L-Methionine+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	DM-LS
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool+L-Tyrosine+stool+L-Tyrosine+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	DM-LS
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool+L-Tryptophan+stool+L-Tyrosine+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	DM-LS
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool+L-Phenylalanine+stool+L-Tyrosine+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	DM-LS
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool+L-Tyrosine+stool+L-Tryptophan+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	DM-LS
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool+L-Tryptophan+stool+L-Tryptophan+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	DM-LS
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool+L-Phenylalanine+stool+L-Tryptophan+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	DM-LS
Rothia	PAI-1	Rothia-PAI-1	Direct	Genus	DM-associated hormones	0.313	5.10E-05	no	no	no	up	up	up	DM-LS
2-hydroxyphenylacetic acid+urine	PAI-1	2-hydroxyphenylacetic acid+urine-L-Tyrosine+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.763	5.10E-05	no	no	no	up	up	up	DM-LS
2-hydroxyphenylacetic acid+urine	PAI-1	2-hydroxyphenylacetic acid+urine-L-Tryptophan+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.763	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnobacterium	PAI-1	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b-PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.867	5.10E-05	no	no	no	up	up	up	DM-LS
Lachnobacterium	PAI-1	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13-PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.867	5.10E-05	no	no	no	up	up	up	DM-LS
Kynurenic acid+stool	PAI-1	Kynurenic acid+stool+L-Tyrosine+stool+L-Tyrosine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.037	5.10E-05	dn	dn	no	up	up	up	DM-LS
Kynurenic acid+stool	PAI-1	Kynurenic acid+stool-UDCA+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.037	5.10E-05	dn	dn	no	up	up	up	DM-LS
Kynurenic acid+stool	PAI-1	Kynurenic acid+stool+L-Tyrosine+stool+L-Tryptophan+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.037	5.10E-05	dn	dn	no	up	up	up	DM-LS
Kynurenic acid+stool	PAI-1	Kynurenic acid+stool+L-Tyrosine+stool+L-Methionine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.037	5.10E-05	dn	dn	no	up	up	up	DM-LS
L-Tryptophan+urine	PAI-1	L-Tryptophan+urine+PAI-1	Direct	urine_cometabolism	DM-associated hormones	0.226	5.10E-05	no	no	no	up	up	up	DM-LS
Anaerostipes	PAI-1	Anaerostipes-PAI-1	Direct	Genus	DM-associated hormones	0.568	5.10E-05	no	no	no	up	up	up	DM-LS
TUDCA+stool	PAI-1	TUDCA+stool-UDCA+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.241	5.10E-05	no	no	no	up	up	up	DM-LS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+L-Phenylalanine+stool+L-Methionine+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-LS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+L-Tyrosine+stool+L-Methionine+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-LS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool-UDCA+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-LS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+L-Phenylalanine+stool+L-Tryptophan+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-LS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+L-Tyrosine+stool+L-Tryptophan+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-LS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+L-Tryptophan+stool+L-Tryptophan+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-LS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+L-Phenylalanine+stool+L-Tyrosine+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-LS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+L-Tyrosine+stool+L-Tyrosine+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-LS
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+L-Tryptophan+stool+L-Tyrosine+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	DM-LS
Paraprevotella	PAI-1	Paraprevotella+Glutathione metabolism-Hypotaurine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-LS
Paraprevotella	PAI-1	Paraprevotella+Arachidonic acid metabolism-Hypotaurine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-LS
Paraprevotella	PAI-1	Paraprevotella+Glutathione metabolism-Prostate cancer+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-LS
Paraprevotella	PAI-1	Paraprevotella+Arachidonic acid metabolism-Prostate cancer+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-LS
Paraprevotella	PAI-1	Paraprevotella+Betaine+blood+L-Isoleucine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-LS
Paraprevotella	PAI-1	Paraprevotella+d18:1-20:0-SM+blood+PDGF-bb+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-LS
Paraprevotella	PAI-1	Paraprevotella+Betaine+blood+L-Citrulline+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	DM-LS
Homovanillic acid+urine	PAI-1	Homovanillic acid+urine-PAI-1	Direct	urine_cometabolism	DM-associated hormones	0.45	5.10E-05	no	no	no	up	up	up	DM-LS
DL-Indole-3-lactic acid+urine	PAI-1	DL-Indole-3-lactic acid+urine+L-Phenylalanine+urine+L-Tyrosine+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.00552	5.10E-05	up	up	no	up	up	up	DM-LS
DL-Indole-3-lactic acid+urine	PAI-1	DL-Indole-3-lactic acid+urine+L-Phenylalanine+urine+L-Tryptophan+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.00552	5.10E-05	up	up	no	up	up	up	DM-LS
L-Tyrosine+urine	PAI-1	L-Tyrosine+urine+PAI-1	Direct	urine_cometabolism	DM-associated hormones	0.45	5.10E-05	no	no	no	up	up	up	DM-LS
iso-LCA+blood	PAI-1	iso-LCA+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.507	5.10E-05	no	no	no	up	up	up	DM-LS
iso-LCA+blood	PAI-1	iso-LCA+blood+L-Proline+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.507	5.10E-05	no	no	no	up	up	up	DM-LS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool+18:2n6c+blood-20:4-LPC+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-LS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool+Cysteine+blood-PDGF-bb+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-LS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool+Cysteine+blood+L-Isoleucine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-LS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool-18:3n6+blood+L-Alanine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-LS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool-UDCA+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-LS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool+Cysteine+blood+L-Methionine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-LS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool-18:3n6+blood-L-Methionine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-LS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool+Cysteine+blood+L-Tyrosine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-LS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool-18:2-LPE+blood-L-Tyrosine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-LS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool+Cysteine+blood+L-Tryptophan+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-LS
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool-18:3n6+blood-L-Tryptophan+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	DM-LS
Gemmiger	PAI-1	Gemmiger+L-Tyrosine+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.595	5.10E-05	no	no	no	up	up	up	DM-LS
Gemmiger	PAI-1	Gemmiger-Homovanillic acid+urine-PAI-1	Indirect	Genus	DM-associated hormones	0.595	5.10E-05	no	no	no	up	up	up	DM-LS
GDCA+stool	PAI-1	GDCA+stool+TCA+stool-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	DM-LS
GDCA+stool	PAI-1	GDCA+stool-L-Isoleucine+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	DM-LS
Methanobrevibacter	PAI-1	Methanobrevibacter+18:0-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.629	5.10E-05	no	no	no	up	up	up	DM-LS
Methanobrevibacter	PAI-1	Methanobrevibacter+L-Citrulline+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.629	5.10E-05	no	no	no	up	up	up	DM-LS
L-Tyrosine+stool	PAI-1	L-Tyrosine+stool+L-Methionine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.44	5.10E-05	no	no	no	up	up	up	DM-LS
L-Tyrosine+stool	PAI-1	L-Tyrosine+stool+L-Tryptophan+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.44	5.10E-05	no	no	no	up	up	up	DM-LS
L-Tyrosine+stool	PAI-1	L-Tyrosine+stool+L-Tyrosine+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.44	5.10E-05	no	no	no	up	up	up	DM-LS
CDCA+stool	PAI-1	CDCA+stool+TCA+stool-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.663	5.10E-05	no	no	no	up	up	up	DM-LS
CA+stool	PAI-1	CA+stool+TCA+stool-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.827	5.10E-05	no	no	no	up	up	up	DM-LS
Slackia	PAI-1	Slackia-16:1/16:1-PC+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.94	5.10E-05	no	no	no	up	up	up	DM-LS
HDCA+blood	PAI-1	HDCA+blood+L-Ornithine+blood+L-Proline+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.483	5.10E-05	no	no	no	up	up	up	DM-LS
HDCA+blood	PAI-1	HDCA+blood+iso-LCA+blood+L-Proline+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.483	5.10E-05	no	no	no	up	up	up	DM-LS
HDCA+blood	PAI-1	HDCA+blood+iso-LCA+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.483	5.10E-05	no	no	no	up	up	up	DM-LS
HDCA+blood	PAI-1	HDCA+blood+L-Ornithine+blood+L-Tryptophan+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.483	5.10E-05	no	no	no	up	up	up	DM-LS
UDCA+stool	PAI-1	UDCA+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.266	5.10E-05	no	no	no	up	up	up	DM-LS
TDCA+stool	PAI-1	TDCA+stool+UDCA+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.963	5.10E-05	no	no	no	up	up	up	DM-LS
LCA+blood	PAI-1	LCA+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.884	5.10E-05	no	no	no	up	up	up	DM-LS
4-hydroxy-3-methoxymandelic acid+urine	PAI-1	4-hydroxy-3-methoxymandelic acid+urine+Homovanillic acid+urine-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.973	5.10E-05	no	no	no	up	up	up	DM-LS
nutriCA+stool	PAI-1	nutriCA+stool-18:2n6c+blood-20:4-LPC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.481	5.10E-05	no	no	no	up	up	up	DM-LS
nutriCA+stool	PAI-1	nutriCA+stool-n3+blood-L-Tryptophan+urine+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.481	5.10E-05	no	no	no	up	up	up	DM-LS
nutriCA+stool	PAI-1	nutriCA+stool+HCA+blood+L-Proline+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.481	5.10E-05	no	no	no	up	up	up	DM-LS
nutriCA+stool	PAI-1	nutriCA+stool-16:0/16:0-PC+blood+16:1/16:1-PC+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.481	5.10E-05	no	no	no	up	up	up	DM-LS
nutriCA+stool	PAI-1	nutriCA+stool+UDCA+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.481	5.10E-05	no	no	no	up	up	up	DM-LS
nutriCA+stool	PAI-1	nutriCA+stool-LCA+blood-Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.481	5.10E-05	no	no	no	up	up	up	DM-LS
GDCA+blood	PAI-1	GDCA+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.632	5.10E-05	no	no	no	up	up	up	DM-LS
acetic acid C2+blood	PAI-1	acetic acid C2+blood-L-Alanine+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.000193	5.10E-05	up	dn	no	up	up	up	DM-LS
isovaleric acid iso-C5+blood	PAI-1	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-1b-PDGF-bb+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.117	5.10E-05	no	no	no	up	up	up	DM-LS
isovaleric acid iso-C5+blood	PAI-1	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.117	5.10E-05	no	no	no	up	up	up	DM-LS
L-Phenylalanine+urine	PAI-1	L-Phenylalanine+urine+L-Tyrosine+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.0908	5.10E-05	no	up	no	up	up	up	DM-LS
L-Phenylalanine+urine	PAI-1	L-Phenylalanine+urine+L-Tryptophan+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.0908	5.10E-05	no	up	no	up	up	up	DM-LS
Adlercreutzia	PAI-1	Adlercreutzia+18:0-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.548	5.10E-05	no	no	no	up	up	up	DM-LS
Clostridium	PAI-1	Clostridium+20:4-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.925	5.10E-05	no	no	no	up	up	up	DM-LS
Clostridium	PAI-1	Clostridium-Butyric acid+stool+PAI-1	Indirect	Genus	DM-associated hormones	0.925	5.10E-05	no	no	no	up	up	up	DM-LS
 Clostridium	PAI-1	Clostridium+Butyric acid+stool+PAI-1	Indirect	Genus	DM-associated hormones	NA	5.10E-05	NA	NA	NA	up	up	up	DM-LS
Clostridium	PAI-1	Clostridium-Butyric acid+stool+PAI-1	Indirect	Genus	DM-associated hormones	0.925	5.10E-05	no	no	no	up	up	up	DM-LS
 Clostridium	PAI-1	Clostridium+Butyric acid+stool+PAI-1	Indirect	Genus	DM-associated hormones	NA	5.10E-05	NA	NA	NA	up	up	up	DM-LS
T-¦Á-MCA+stool	PAI-1	T-¦Á-MCA+stool-TCA+stool-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.48	5.10E-05	no	no	no	up	up	up	DM-LS
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-20:4-LPC+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	DM-LS
Butyricicoccus	PAI-1	Butyricicoccus+Butyric acid+stool+PAI-1	Indirect	Genus	DM-associated hormones	0.852	5.10E-05	no	no	no	up	up	up	DM-LS
3-Hydroxy-L-kynurenine+urine	PAI-1	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.401	5.10E-05	no	no	no	up	up	up	DM-LS
3-Hydroxy-L-kynurenine+urine	PAI-1	3-Hydroxy-L-kynurenine+urine+L-Tyrosine+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.401	5.10E-05	no	no	no	up	up	up	DM-LS
Blautia	MCP-1(MCAF)	"Blautia+d18:1-16:1-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	DM-LS
Blautia	MCP-1(MCAF)	Blautia+14:0/20:4-PC+blood-16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	DM-LS
Blautia	MCP-1(MCAF)	Blautia-20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	DM-LS
Blautia	MCP-1(MCAF)	Blautia-16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	DM-LS
Blautia	MCP-1(MCAF)	Blautia-16:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	DM-LS
Blautia	MCP-1(MCAF)	Blautia-18:1/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	DM-LS
Blautia	MCP-1(MCAF)	Blautia-18:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	DM-LS
Blautia	MCP-1(MCAF)	Blautia-20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	DM-LS
Blautia	MCP-1(MCAF)	Blautia-16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	DM-LS
Blautia	MCP-1(MCAF)	Blautia-16:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	DM-LS
Blautia	MCP-1(MCAF)	Blautia+d18:0-24:1-SM+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	DM-LS
Blautia	MCP-1(MCAF)	Blautia-18:1/16:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	DM-LS
Blautia	MCP-1(MCAF)	Blautia-18:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	DM-LS
Blautia	MCP-1(MCAF)	Blautia-16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	DM-LS
Blautia	MCP-1(MCAF)	Blautia-16:0/18:2-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	DM-LS
Blautia	MCP-1(MCAF)	Blautia+14:0/20:4-PC+blood-18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	DM-LS
Parabacteroides	MCP-1(MCAF)	Parabacteroides+Apoptosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	4.19E-05	0.0633	no	up	up	dn	no	up	DM-LS
Dorea	MCP-1(MCAF)	"Dorea+d18:1-20:0-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.00362	0.0633	up	no	dn	dn	no	up	DM-LS
Faecalibacterium	MCP-1(MCAF)	Faecalibacterium-16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0039	0.0633	no	dn	dn	dn	no	up	DM-LS
TUDCA+blood	MCP-1(MCAF)	TUDCA+blood+Eotaxin-GM-CSF-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.0282	0.0633	no	no	dn	dn	no	up	DM-LS
isocapric acid iso-C6+blood	MCP-1(MCAF)	isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF-MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.0458	0.0633	no	no	dn	dn	no	up	DM-LS
Bacteroides	MCP-1(MCAF)	Bacteroides+Cytokine-cytokine receptor interaction+Hepatocellular carcinoma-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-LS
Bacteroides	MCP-1(MCAF)	Bacteroides+Cytokine-cytokine receptor interaction+Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-LS
Bacteroides	MCP-1(MCAF)	Bacteroides+Cytokine-cytokine receptor interaction+Leukocyte transendothelial migration-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-LS
Bacteroides	MCP-1(MCAF)	Bacteroides-GCA+stool+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-LS
Bacteroides	MCP-1(MCAF)	Bacteroides+Cytokine-cytokine receptor interaction-18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-LS
Bacteroides	MCP-1(MCAF)	Bacteroides+Cytokine-cytokine receptor interaction+Influenza A-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-LS
Bacteroides	MCP-1(MCAF)	Bacteroides-8-HETE+blood+AA+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-LS
Bacteroides	MCP-1(MCAF)	Bacteroides-GCA+stool+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-LS
Bacteroides	MCP-1(MCAF)	Bacteroides+Cytokine-cytokine receptor interaction-16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-LS
Bacteroides	MCP-1(MCAF)	Bacteroides+Cytokine-cytokine receptor interaction+Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-LS
Bacteroides	MCP-1(MCAF)	Bacteroides+Cytokine-cytokine receptor interaction+Yersinia infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-LS
Bacteroides	MCP-1(MCAF)	Bacteroides+Cytokine-cytokine receptor interaction+Adherens junction-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	DM-LS
Propionic acid+stool	MCP-1(MCAF)	Propionic acid+stool-TCA+stool+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.0436	0.0633	dn	no	up	dn	no	up	DM-LS
Propionic acid+stool	MCP-1(MCAF)	Propionic acid+stool-TCA+stool+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.0436	0.0633	dn	no	up	dn	no	up	DM-LS
Propionic acid+stool	MCP-1(MCAF)	Propionic acid+stool-18:1/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.0436	0.0633	dn	no	up	dn	no	up	DM-LS
Propionic acid+stool	MCP-1(MCAF)	Propionic acid+stool-18:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.0436	0.0633	dn	no	up	dn	no	up	DM-LS
Propionic acid+stool	MCP-1(MCAF)	Propionic acid+stool-18:1/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.0436	0.0633	dn	no	up	dn	no	up	DM-LS
Propionic acid+stool	MCP-1(MCAF)	Propionic acid+stool-18:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.0436	0.0633	dn	no	up	dn	no	up	DM-LS
[Ruminococcus]	MCP-1(MCAF)	[Ruminococcus]+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0679	0.0633	no	no	dn	dn	no	up	DM-LS
GUDCA+blood	MCP-1(MCAF)	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0633	no	no	dn	dn	no	up	DM-LS
Acetic acid+stool	MCP-1(MCAF)	Acetic acid+stool+AA+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.0656	0.0633	dn	no	no	dn	no	up	DM-LS
Alistipes	MCP-1(MCAF)	Alistipes-HIF-1 signaling pathway-Fc epsilon RI signaling pathway-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0114	0.0633	no	up	no	dn	no	up	DM-LS
Alistipes	MCP-1(MCAF)	Alistipes-HIF-1 signaling pathway+Protein processing in endoplasmic reticulum+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0114	0.0633	no	up	no	dn	no	up	DM-LS
Alistipes	MCP-1(MCAF)	Alistipes+12-ketoDCA+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0114	0.0633	no	up	no	dn	no	up	DM-LS
Alistipes	MCP-1(MCAF)	Alistipes-HIF-1 signaling pathway+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0114	0.0633	no	up	no	dn	no	up	DM-LS
Alistipes	MCP-1(MCAF)	Alistipes-HIF-1 signaling pathway-Apoptosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0114	0.0633	no	up	no	dn	no	up	DM-LS
Alistipes	MCP-1(MCAF)	Alistipes-HIF-1 signaling pathway+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0114	0.0633	no	up	no	dn	no	up	DM-LS
Butyricimonas	MCP-1(MCAF)	Butyricimonas-Prion disease+Hepatocellular carcinoma-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	DM-LS
Butyricimonas	MCP-1(MCAF)	Butyricimonas-Cardiac muscle contraction+Hepatocellular carcinoma-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	DM-LS
Butyricimonas	MCP-1(MCAF)	Butyricimonas-14:0/20:4-PC+blood-16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	DM-LS
Butyricimonas	MCP-1(MCAF)	Butyricimonas-14:0/20:4-PC+blood-18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	DM-LS
Butyricimonas	MCP-1(MCAF)	Butyricimonas-Cardiac muscle contraction+Adherens junction-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	DM-LS
Butyricimonas	MCP-1(MCAF)	"Butyricimonas-Cardiac muscle contraction+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	DM-LS
Butyricimonas	MCP-1(MCAF)	"Butyricimonas-d18:1-14:0-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	DM-LS
Butyricimonas	MCP-1(MCAF)	Butyricimonas-d18:0-24:1-SM+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	DM-LS
Butyricimonas	MCP-1(MCAF)	Butyricimonas+20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	DM-LS
Butyricimonas	MCP-1(MCAF)	Butyricimonas-d18:1-14:0-SM+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	DM-LS
Butyricimonas	MCP-1(MCAF)	Butyricimonas+20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-T cell receptor signaling pathway-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Signaling pathways regulating pluripotency of stem cells-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-RNA degradation-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Spinocerebellar ataxia-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Long-term potentiation-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Insulin resistance-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Prostate cancer-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-NF-kappa B signaling pathway-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Gastric cancer-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-MicroRNAs in cancer-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Phosphatidylinositol signaling system-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-PD-L1 expression and PD-1 checkpoint pathway in cancer-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-NF-kappa B signaling pathway-Adherens junction-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-NF-kappa B signaling pathway+Fc epsilon RI signaling pathway-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-ErbB signaling pathway+Fc epsilon RI signaling pathway-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-NF-kappa B signaling pathway-Hepatocellular carcinoma-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Phosphatidylinositol signaling system-Influenza A-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	"Collinsella+Parkinson disease+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella+Parkinson disease-AA+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-RNA degradation-Apoptosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Phosphatidylinositol signaling system-Apoptosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-RNA degradation-Rap1 signaling pathway-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Wnt signaling pathway-Leukocyte transendothelial migration-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Signaling pathways regulating pluripotency of stem cells-Leukocyte transendothelial migration-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-RNA degradation-Leukocyte transendothelial migration-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Phosphatidylinositol signaling system-Leukocyte transendothelial migration-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-RNA degradation-Yersinia infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Phosphatidylinositol signaling system-Yersinia infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Wnt signaling pathway-Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Signaling pathways regulating pluripotency of stem cells-Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-RNA degradation-Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Spinocerebellar ataxia-Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Insulin resistance-Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Phosphatidylinositol signaling system-Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella-Long-term potentiation-Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
Collinsella	MCP-1(MCAF)	Collinsella+20:1-LPA+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	DM-LS
total_blood_scfa+blood	MCP-1(MCAF)	total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF-MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.168	0.0633	no	no	no	dn	no	up	DM-LS
[Eubacterium]	MCP-1(MCAF)	[Eubacterium]-Yersinia infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0692	0.0633	no	no	no	dn	no	up	DM-LS
[Eubacterium]	MCP-1(MCAF)	[Eubacterium]-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0692	0.0633	no	no	no	dn	no	up	DM-LS
[Eubacterium]	MCP-1(MCAF)	[Eubacterium]-Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0692	0.0633	no	no	no	dn	no	up	DM-LS
[Eubacterium]	MCP-1(MCAF)	[Eubacterium]-Influenza A-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0692	0.0633	no	no	no	dn	no	up	DM-LS
LCA+stool	MCP-1(MCAF)	LCA+stool+18:1/18:1-PE+blood-Betaine+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.314	0.0633	no	no	no	dn	no	up	DM-LS
LCA+stool	MCP-1(MCAF)	LCA+stool-TCA+stool+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.314	0.0633	no	no	no	dn	no	up	DM-LS
LCA+stool	MCP-1(MCAF)	LCA+stool-TCA+stool+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.314	0.0633	no	no	no	dn	no	up	DM-LS
LCA+stool	MCP-1(MCAF)	LCA+stool-Cystine+blood-DCA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.314	0.0633	no	no	no	dn	no	up	DM-LS
LCA+stool	MCP-1(MCAF)	"LCA+stool+12,13-EPOME+blood+DCA+blood+MCP-1(MCAF)"	Indirect	stool_bileacids	serum_cytokines	0.314	0.0633	no	no	no	dn	no	up	DM-LS
Akkermansia	MCP-1(MCAF)	Akkermansia+Apoptosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.23	0.0633	no	no	no	dn	no	up	DM-LS
Bifidobacterium	MCP-1(MCAF)	"Bifidobacterium+d18:1-18:1-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.105	0.0633	no	dn	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Type I diabetes mellitus+Yersinia infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Endocytosis+Yersinia infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Phagosome+Yersinia infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Cell adhesion molecules+Yersinia infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Phagosome+Apoptosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Phagosome+Adherens junction-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Type I diabetes mellitus+Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Natural killer cell mediated cytotoxicity+Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Endocytosis+Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Phagosome+Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Cell adhesion molecules+Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Type I diabetes mellitus+Influenza A-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Endocytosis+Influenza A-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Phagosome+Influenza A-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Cell adhesion molecules+Influenza A-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Phagosome+Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Cell adhesion molecules+Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Phagosome+Leukocyte transendothelial migration-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
Ruminococcus	MCP-1(MCAF)	Ruminococcus+Cell adhesion molecules+Leukocyte transendothelial migration-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	DM-LS
GCDCA+blood	MCP-1(MCAF)	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.31	0.0633	no	no	no	dn	no	up	DM-LS
Succinivibrio	MCP-1(MCAF)	Succinivibrio-Phospholipase D signaling pathway+Fc epsilon RI signaling pathway-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.138	0.0633	no	no	no	dn	no	up	DM-LS
Succinivibrio	MCP-1(MCAF)	Succinivibrio-Phospholipase D signaling pathway-Protein processing in endoplasmic reticulum+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.138	0.0633	no	no	no	dn	no	up	DM-LS
Succinivibrio	MCP-1(MCAF)	Succinivibrio-Phospholipase D signaling pathway+AA+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.138	0.0633	no	no	no	dn	no	up	DM-LS
ACA+blood	MCP-1(MCAF)	ACA+blood-Eotaxin-GM-CSF-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.338	0.0633	no	no	no	dn	no	up	DM-LS
DCA+stool	MCP-1(MCAF)	DCA+stool-18:1/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.195	0.0633	no	no	no	dn	no	up	DM-LS
DCA+stool	MCP-1(MCAF)	DCA+stool-18:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.195	0.0633	no	no	no	dn	no	up	DM-LS
DCA+stool	MCP-1(MCAF)	DCA+stool-18:1/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.195	0.0633	no	no	no	dn	no	up	DM-LS
DCA+stool	MCP-1(MCAF)	DCA+stool-18:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.195	0.0633	no	no	no	dn	no	up	DM-LS
DCA+stool	MCP-1(MCAF)	"DCA+stool+12,13-EPOME+blood+DCA+blood+MCP-1(MCAF)"	Indirect	stool_bileacids	serum_cytokines	0.195	0.0633	no	no	no	dn	no	up	DM-LS
DCA+stool	MCP-1(MCAF)	DCA+stool-Cystine+blood-DCA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.195	0.0633	no	no	no	dn	no	up	DM-LS
DCA+stool	MCP-1(MCAF)	DCA+stool-GCA+stool+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.195	0.0633	no	no	no	dn	no	up	DM-LS
DCA+stool	MCP-1(MCAF)	DCA+stool-TCA+stool+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.195	0.0633	no	no	no	dn	no	up	DM-LS
DCA+stool	MCP-1(MCAF)	DCA+stool-GCA+stool+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.195	0.0633	no	no	no	dn	no	up	DM-LS
DCA+stool	MCP-1(MCAF)	DCA+stool-16:0/20:3-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.195	0.0633	no	no	no	dn	no	up	DM-LS
DCA+stool	MCP-1(MCAF)	DCA+stool-TCA+stool+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.195	0.0633	no	no	no	dn	no	up	DM-LS
DCA+stool	MCP-1(MCAF)	DCA+stool+18:1/18:1-PE+blood-Betaine+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.195	0.0633	no	no	no	dn	no	up	DM-LS
2-hydroxyhippuric acid+urine	MCP-1(MCAF)	"2-hydroxyhippuric acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	urine_cometabolism	serum_cytokines	0.215	0.0633	no	no	no	dn	no	up	DM-LS
Butyric acid+stool	MCP-1(MCAF)	Butyric acid+stool+AA+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.102	0.0633	dn	no	no	dn	no	up	DM-LS
4-hydroxybenzoic acid+stool	MCP-1(MCAF)	"4-hydroxybenzoic acid+stool-12,13-EPOME+blood+DCA+blood+MCP-1(MCAF)"	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.0633	no	dn	no	dn	no	up	DM-LS
GCA+blood	MCP-1(MCAF)	GCA+blood+TCA+blood+TUDCA+blood+Eotaxin-GM-CSF-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.16	0.0633	no	no	no	dn	no	up	DM-LS
ACA+stool	MCP-1(MCAF)	ACA+stool-GCA+stool+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.417	0.0633	no	no	no	dn	no	up	DM-LS
ACA+stool	MCP-1(MCAF)	ACA+stool-GCA+stool+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.417	0.0633	no	no	no	dn	no	up	DM-LS
ACA+stool	MCP-1(MCAF)	"ACA+stool+16:0-LPC+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_bileacids	serum_cytokines	0.417	0.0633	no	no	no	dn	no	up	DM-LS
ACA+stool	MCP-1(MCAF)	ACA+stool+20:2+blood+Betaine+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.417	0.0633	no	no	no	dn	no	up	DM-LS
ACA+stool	MCP-1(MCAF)	ACA+stool+20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.417	0.0633	no	no	no	dn	no	up	DM-LS
ACA+stool	MCP-1(MCAF)	ACA+stool+20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.417	0.0633	no	no	no	dn	no	up	DM-LS
CDCA+blood	MCP-1(MCAF)	CDCA+blood+DCA+blood+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.506	0.0633	no	no	no	dn	no	up	DM-LS
capric acid C6+blood	MCP-1(MCAF)	capric acid C6+blood-DCA+blood+MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.433	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter-Carbon metabolism+Apoptosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter-Lysosome+Apoptosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter-Carbon metabolism+Leukocyte transendothelial migration-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter-Lysosome+Leukocyte transendothelial migration-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	"Pyramidobacter+Parathyroid hormone synthesis, secretion and action-Betaine+blood-MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter-Carbon metabolism+Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter-Lysosome+Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter+Glucagon signaling pathway-Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter+Insulin resistance-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter-Carbon metabolism+Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter-Lysosome+Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter+Glucagon signaling pathway-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter+Small cell lung cancer-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter+Pathways in cancer-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter+Prostate cancer-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter-Lysosome+Influenza A-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter+Glucagon signaling pathway-Influenza A-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter-Lysosome+Fc epsilon RI signaling pathway-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter+Insulin resistance-Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter-Carbon metabolism+Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter-Lysosome+Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter+Glucagon signaling pathway-Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter-Lysosome+Yersinia infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter+Glucagon signaling pathway-Yersinia infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter+Small cell lung cancer-Hepatocellular carcinoma-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter-Carbon metabolism-DCA+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter-Lysosome-DCA+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	Pyramidobacter+Pathways in cancer+DCA+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Pyramidobacter	MCP-1(MCAF)	"Pyramidobacter+Parathyroid hormone synthesis, secretion and action+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.45	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella-Carbon metabolism+Apoptosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Calcium signaling pathway-Apoptosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella-Carbon metabolism+Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Cushing syndrome-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Phospholipase D signaling pathway+AA+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Melanogenesis-AA+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella-Carbon metabolism+Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Cocaine addiction-Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+18:0-LPC+blood+Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Aldosterone synthesis and secretion-Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+GnRH signaling pathway-Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Adrenergic signaling in cardiomyocytes-Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Inflammatory mediator regulation of TRP channels-Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella-Carbon metabolism+Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Calcium signaling pathway-Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Amphetamine addiction-Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Dopaminergic synapse-Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Cushing syndrome-Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Melanogenesis-Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Cocaine addiction+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Aldosterone synthesis and secretion+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+GnRH signaling pathway+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Calcium signaling pathway+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Pancreatic secretion+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Long-term depression+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Amphetamine addiction+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Dopaminergic synapse+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Cocaine addiction+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Aldosterone synthesis and secretion+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+GnRH signaling pathway+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Adrenergic signaling in cardiomyocytes+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Inflammatory mediator regulation of TRP channels+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Calcium signaling pathway+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Pancreatic secretion+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Long-term depression+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Amphetamine addiction+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Dopaminergic synapse+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Melanogenesis+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella-Glycolysis / Gluconeogenesis+Leukocyte transendothelial migration-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella-Carbon metabolism+Leukocyte transendothelial migration-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Phospholipase D signaling pathway+Fc epsilon RI signaling pathway-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella-Proteasome+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella-Proteasome+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Aldosterone synthesis and secretion+DCA+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella-Carbon metabolism-DCA+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Calcium signaling pathway+DCA+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Cushing syndrome+DCA+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	Prevotella+Phospholipase D signaling pathway-Protein processing in endoplasmic reticulum+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	"Prevotella+Cocaine addiction+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	"Prevotella+Cortisol synthesis and secretion+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	"Prevotella+Long-term depression+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
Prevotella	MCP-1(MCAF)	"Prevotella+Morphine addiction+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	DM-LS
TCA+blood	MCP-1(MCAF)	TCA+blood+TUDCA+blood+Eotaxin-GM-CSF-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.339	0.0633	no	no	no	dn	no	up	DM-LS
iso-DCA+blood	MCP-1(MCAF)	"iso-DCA+blood+L-Leucine+blood+L-Methionine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	serum_bileacids	serum_cytokines	0.38	0.0633	no	no	no	dn	no	up	DM-LS
iso-DCA+blood	MCP-1(MCAF)	"iso-DCA+blood+L-Lysine+blood+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	serum_bileacids	serum_cytokines	0.38	0.0633	no	no	no	dn	no	up	DM-LS
iso-DCA+blood	MCP-1(MCAF)	"iso-DCA+blood+L-Leucine+blood+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	serum_bileacids	serum_cytokines	0.38	0.0633	no	no	no	dn	no	up	DM-LS
HCA+stool	MCP-1(MCAF)	HCA+stool-18:0/20:5-PC+blood+Betaine+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.155	0.0633	no	no	no	dn	no	up	DM-LS
HCA+stool	MCP-1(MCAF)	HCA+stool-18:0/20:4-PC+blood+20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.155	0.0633	no	no	no	dn	no	up	DM-LS
HCA+stool	MCP-1(MCAF)	HCA+stool-18:1+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.155	0.0633	no	no	no	dn	no	up	DM-LS
HCA+stool	MCP-1(MCAF)	HCA+stool+CDCA+blood+DCA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.155	0.0633	no	no	no	dn	no	up	DM-LS
HCA+stool	MCP-1(MCAF)	HCA+stool-18:0/20:4-PC+blood-DCA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.155	0.0633	no	no	no	dn	no	up	DM-LS
HCA+stool	MCP-1(MCAF)	HCA+stool-18:0/20:5-PC+blood+AA+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.155	0.0633	no	no	no	dn	no	up	DM-LS
HCA+stool	MCP-1(MCAF)	HCA+stool-16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.155	0.0633	no	no	no	dn	no	up	DM-LS
Roseburia	MCP-1(MCAF)	Roseburia-20:2+blood+Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.495	0.0633	no	no	no	dn	no	up	DM-LS
Roseburia	MCP-1(MCAF)	Roseburia-18:2n6c+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.495	0.0633	no	no	no	dn	no	up	DM-LS
Roseburia	MCP-1(MCAF)	"Roseburia-16:0-LPC+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.495	0.0633	no	no	no	dn	no	up	DM-LS
12-ketoDCA+stool	MCP-1(MCAF)	12-ketoDCA+stool+18:1/18:1-PE+blood-Betaine+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.505	0.0633	no	no	no	dn	no	up	DM-LS
GLCA+blood	MCP-1(MCAF)	"GLCA+blood+L-Homocystine+blood-2-hydroxyhippuric acid+urine-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	serum_bileacids	serum_cytokines	0.319	0.0633	no	no	no	dn	no	up	DM-LS
L-Tryptophan+stool	MCP-1(MCAF)	L-Tryptophan+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0633	no	no	no	dn	no	up	DM-LS
L-Tryptophan+stool	MCP-1(MCAF)	L-Tryptophan+stool+18:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0633	no	no	no	dn	no	up	DM-LS
L-Tryptophan+stool	MCP-1(MCAF)	L-Tryptophan+stool+16:1/16:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0633	no	no	no	dn	no	up	DM-LS
L-Tryptophan+stool	MCP-1(MCAF)	L-Tryptophan+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0633	no	no	no	dn	no	up	DM-LS
L-Tryptophan+stool	MCP-1(MCAF)	"L-Tryptophan+stool+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0633	no	no	no	dn	no	up	DM-LS
L-Tryptophan+stool	MCP-1(MCAF)	L-Tryptophan+stool+16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0633	no	no	no	dn	no	up	DM-LS
L-Tryptophan+stool	MCP-1(MCAF)	L-Tryptophan+stool+16:1/16:0-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0633	no	no	no	dn	no	up	DM-LS
L-Tryptophan+stool	MCP-1(MCAF)	L-Tryptophan+stool+16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0633	no	no	no	dn	no	up	DM-LS
L-Tryptophan+stool	MCP-1(MCAF)	L-Tryptophan+stool+18:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0633	no	no	no	dn	no	up	DM-LS
L-Tryptophan+stool	MCP-1(MCAF)	L-Tryptophan+stool+16:1/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0633	no	no	no	dn	no	up	DM-LS
L-Tryptophan+stool	MCP-1(MCAF)	L-Tryptophan+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0633	no	no	no	dn	no	up	DM-LS
CA+blood	MCP-1(MCAF)	CA+blood+DCA+blood+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.606	0.0633	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	MCP-1(MCAF)	L-Phenylalanine+stool+18:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0633	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	MCP-1(MCAF)	L-Phenylalanine+stool+20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0633	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	MCP-1(MCAF)	L-Phenylalanine+stool+18:2/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0633	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	MCP-1(MCAF)	L-Phenylalanine+stool+16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0633	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	MCP-1(MCAF)	L-Phenylalanine+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0633	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	MCP-1(MCAF)	L-Phenylalanine+stool+16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0633	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	MCP-1(MCAF)	L-Phenylalanine+stool+18:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0633	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	MCP-1(MCAF)	L-Phenylalanine+stool+20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0633	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	MCP-1(MCAF)	L-Phenylalanine+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0633	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	MCP-1(MCAF)	L-Phenylalanine+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0633	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	MCP-1(MCAF)	"L-Phenylalanine+stool+L-Methionine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0633	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	MCP-1(MCAF)	"L-Phenylalanine+stool+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0633	no	no	no	dn	no	up	DM-LS
L-Phenylalanine+stool	MCP-1(MCAF)	L-Phenylalanine+stool+16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0633	no	no	no	dn	no	up	DM-LS
butyric acid C4+blood	MCP-1(MCAF)	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF-MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.407	0.0633	no	no	no	dn	no	up	DM-LS
GCA+stool	MCP-1(MCAF)	GCA+stool+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-LS
GCA+stool	MCP-1(MCAF)	GCA+stool+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	DM-LS
T-a-MCA+blood	MCP-1(MCAF)	T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.478	0.0633	no	no	no	dn	no	up	DM-LS
Coprococcus	MCP-1(MCAF)	Coprococcus+Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	DM-LS
Oscillospira	MCP-1(MCAF)	Oscillospira-Alzheimer disease+Hepatocellular carcinoma-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	DM-LS
Oscillospira	MCP-1(MCAF)	Oscillospira-Adrenergic signaling in cardiomyocytes-Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	DM-LS
Oscillospira	MCP-1(MCAF)	Oscillospira-Alzheimer disease-Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	DM-LS
Oscillospira	MCP-1(MCAF)	Oscillospira+Peroxisome-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	DM-LS
Oscillospira	MCP-1(MCAF)	Oscillospira-Adrenergic signaling in cardiomyocytes+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	DM-LS
Oscillospira	MCP-1(MCAF)	Oscillospira+Peroxisome-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	DM-LS
HCA+blood	MCP-1(MCAF)	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin-GM-CSF-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.544	0.0633	no	no	no	dn	no	up	DM-LS
iso-LCA+stool	MCP-1(MCAF)	iso-LCA+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.72	0.0633	no	no	no	dn	no	up	DM-LS
iso-LCA+stool	MCP-1(MCAF)	iso-LCA+stool-CDCA+blood+DCA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.72	0.0633	no	no	no	dn	no	up	DM-LS
iso-LCA+stool	MCP-1(MCAF)	iso-LCA+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.72	0.0633	no	no	no	dn	no	up	DM-LS
iso-LCA+stool	MCP-1(MCAF)	iso-LCA+stool-TCA+stool+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.72	0.0633	no	no	no	dn	no	up	DM-LS
iso-LCA+stool	MCP-1(MCAF)	iso-LCA+stool-TCA+stool+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.72	0.0633	no	no	no	dn	no	up	DM-LS
2-methyl-butyric acid m-C4+blood	MCP-1(MCAF)	2-methyl-butyric acid m-C4+blood-CA+blood+DCA+blood+MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.262	0.0633	no	no	no	dn	no	up	DM-LS
DCA+blood	MCP-1(MCAF)	DCA+blood+MCP-1(MCAF)	Direct	serum_bileacids	serum_cytokines	0.122	0.0633	no	no	no	dn	no	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool-20:0/20:5-PC+blood-DCA+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool+18:2/18:2-PS+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/20:5-PC+blood+Betaine+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/20:5-PC+blood+AA+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool-20:0/20:5-PC+blood+AA+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	"3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2n6c+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool+18:2/18:2-PS+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	DM-LS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	MCP-1(MCAF)	"3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Direct	urine_cometabolism	serum_cytokines	0.0125	0.0633	up	up	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tyrosine+stool-16:1+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+18:2n6c+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tryptophan+stool+16:1/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tyrosine+stool+18:1/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tryptophan+stool+16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tyrosine+stool+16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tryptophan+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tyrosine+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tryptophan+stool+18:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+18:2/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tyrosine+stool+18:2/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+18:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tyrosine+stool+18:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tyrosine+stool+16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tryptophan+stool+16:1/16:0-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tryptophan+stool+16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tyrosine+stool+16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tyrosine+stool-16:1+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	"Indole-3-Acetic acid+stool+L-Phenylalanine+stool+L-Methionine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	"Indole-3-Acetic acid+stool+L-Tyrosine+stool+L-Methionine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	"Indole-3-Acetic acid+stool+L-Tryptophan+stool+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	"Indole-3-Acetic acid+stool+L-Phenylalanine+stool+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	"Indole-3-Acetic acid+stool+L-Tyrosine+stool+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tyrosine+stool-18:1/18:1-PE+blood-Betaine+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tyrosine+stool-16:1+blood-Betaine+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tryptophan+stool+16:1/16:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tyrosine+stool+18:1/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tryptophan+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tyrosine+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tryptophan+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tyrosine+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tryptophan+stool+18:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+18:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tyrosine+stool+18:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	DM-LS
TCA+stool	MCP-1(MCAF)	TCA+stool+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.458	0.0633	no	no	no	dn	no	up	DM-LS
TCA+stool	MCP-1(MCAF)	TCA+stool+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.458	0.0633	no	no	no	dn	no	up	DM-LS
HDCA+stool	MCP-1(MCAF)	HDCA+stool-20:1-LPA+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.176	0.0633	no	no	no	dn	no	up	DM-LS
HDCA+stool	MCP-1(MCAF)	HDCA+stool-18:1/20:3-PC+blood-DCA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.176	0.0633	no	no	no	dn	no	up	DM-LS
HDCA+stool	MCP-1(MCAF)	"HDCA+stool+12,13-EPOME+blood+DCA+blood+MCP-1(MCAF)"	Indirect	stool_bileacids	serum_cytokines	0.176	0.0633	no	no	no	dn	no	up	DM-LS
HDCA+stool	MCP-1(MCAF)	"HDCA+stool-16:0-LPC+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_bileacids	serum_cytokines	0.176	0.0633	no	no	no	dn	no	up	DM-LS
HDCA+stool	MCP-1(MCAF)	HDCA+stool-18:1-LPC+blood+Betaine+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.176	0.0633	no	no	no	dn	no	up	DM-LS
HDCA+stool	MCP-1(MCAF)	HDCA+stool-16:0/20:3-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.176	0.0633	no	no	no	dn	no	up	DM-LS
Lachnospira	MCP-1(MCAF)	Lachnospira-Adherens junction-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.279	0.0633	no	no	no	dn	no	up	DM-LS
Fusobacterium	MCP-1(MCAF)	Fusobacterium+16:0/20:3-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.628	0.0633	no	no	no	dn	no	up	DM-LS
isobutyric acid C4+blood	MCP-1(MCAF)	isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF-MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.0151	0.0633	up	up	no	dn	no	up	DM-LS
GCDCA+stool	MCP-1(MCAF)	GCDCA+stool+TCA+stool+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0633	no	dn	no	dn	no	up	DM-LS
GCDCA+stool	MCP-1(MCAF)	GCDCA+stool+CA+blood+DCA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0633	no	dn	no	dn	no	up	DM-LS
GCDCA+stool	MCP-1(MCAF)	GCDCA+stool+TCA+stool+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0633	no	dn	no	dn	no	up	DM-LS
5-Hydroxytryptamine+stool	MCP-1(MCAF)	5-Hydroxytryptamine+stool-Acetic acid+stool+AA+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0633	dn	dn	no	dn	no	up	DM-LS
Odoribacter	MCP-1(MCAF)	Odoribacter-14:0/16:0-PC+blood+16:0/16:1-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.798	0.0633	no	no	no	dn	no	up	DM-LS
Odoribacter	MCP-1(MCAF)	Odoribacter-14:0/16:0-PC+blood-Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.798	0.0633	no	no	no	dn	no	up	DM-LS
Odoribacter	MCP-1(MCAF)	Odoribacter-d18:0-24:1-SM+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.798	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tyrosine+stool+18:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Phenylalanine+stool+18:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tryptophan+stool+18:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool-16:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tyrosine+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool+18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tryptophan+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+Phenylacetic acid+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Phenylalanine+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tyrosine+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool-16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tryptophan+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Phenylalanine+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool-20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tryptophan+stool+16:1/16:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tyrosine+stool+18:1/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool-16:0/18:2-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tyrosine+stool+16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool-16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tryptophan+stool+16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Phenylalanine+stool+16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tryptophan+stool+16:1/16:0-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tyrosine+stool-16:1+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tyrosine+stool+18:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Phenylalanine+stool+18:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tryptophan+stool+18:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool-16:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tyrosine+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool+18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tryptophan+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+Phenylacetic acid+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Phenylalanine+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tyrosine+stool+18:2/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool-18:2/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Phenylalanine+stool+18:2/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool-18:3n3+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-nutriCA+stool-18:3n3+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tyrosine+stool+16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool-16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tryptophan+stool+16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Phenylalanine+stool+16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool-20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tryptophan+stool+16:1/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tyrosine+stool+18:1/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool+CDCA+blood+DCA+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool-20:0/20:5-PC+blood-DCA+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-nutriCA+stool+CA+blood+DCA+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool-18:2n6c+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+Phenylacetic acid+stool+18:2n6c+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-nutriCA+stool-18:2n6c+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tyrosine+stool-16:1+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool-18:0/20:5-PC+blood+AA+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool-20:0/20:5-PC+blood+AA+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	"Isobutyric acid+stool-UDCA+stool+d18:1-16:1-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	"Isobutyric acid+stool+L-Tyrosine+stool+L-Methionine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	"Isobutyric acid+stool+L-Phenylalanine+stool+L-Methionine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	"Isobutyric acid+stool+L-Tyrosine+stool+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	"Isobutyric acid+stool+L-Tryptophan+stool+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	"Isobutyric acid+stool+L-Phenylalanine+stool+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tyrosine+stool+16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool-16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Phenylalanine+stool+16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-nutriCA+stool-16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool-UDCA+stool-18:0/20:5-PC+blood+Betaine+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tyrosine+stool-18:1/18:1-PE+blood-Betaine+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+L-Tyrosine+stool-16:1+blood-Betaine+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	DM-LS
Lachnobacterium	MCP-1(MCAF)	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.867	0.0633	no	no	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool-16:1+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool-18:2n6c+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-nutriCA+stool-18:2n6c+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool-16:1+blood-Betaine+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool-18:1/18:1-PE+blood-Betaine+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool-18:0/20:5-PC+blood+Betaine+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool-18:0/20:5-PC+blood+AA+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool-20:0/20:5-PC+blood+AA+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool-16:1+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool-16:0/18:2-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool-16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool+16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool-18:2/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool+18:2/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool+18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool-16:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool+18:1/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool-18:3n3+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-nutriCA+stool-18:3n3+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool+18:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool-16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool+16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool-20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool+CDCA+blood+DCA+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-nutriCA+stool+CA+blood+DCA+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool-20:0/20:5-PC+blood-DCA+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	"Kynurenic acid+stool-UDCA+stool+d18:1-16:1-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	"Kynurenic acid+stool+L-Tyrosine+stool+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	"Kynurenic acid+stool+L-Tyrosine+stool+L-Methionine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool+18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool-16:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool+18:1/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool+18:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool-16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool-20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-UDCA+stool-16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-nutriCA+stool-16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool+L-Tyrosine+stool+16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	DM-LS
Anaerostipes	MCP-1(MCAF)	Anaerostipes-Insulin resistance-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.568	0.0633	no	no	no	dn	no	up	DM-LS
Anaerostipes	MCP-1(MCAF)	Anaerostipes-Prostate cancer-Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.568	0.0633	no	no	no	dn	no	up	DM-LS
Anaerostipes	MCP-1(MCAF)	"Anaerostipes+15-HETE+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.568	0.0633	no	no	no	dn	no	up	DM-LS
Anaerostipes	MCP-1(MCAF)	Anaerostipes-Insulin resistance-Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.568	0.0633	no	no	no	dn	no	up	DM-LS
Anaerostipes	MCP-1(MCAF)	Anaerostipes-B cell receptor signaling pathway+Fc epsilon RI signaling pathway-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.568	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool-18:2n6c+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool-18:0/20:5-PC+blood+Betaine+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool-16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool-16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool-16:0/18:2-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool+18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool-18:2/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool-16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool-16:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool-18:3n3+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool-20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool+18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool-16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool-16:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool-20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	"TUDCA+stool-UDCA+stool+d18:1-16:1-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool-20:0/20:5-PC+blood-DCA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool+CDCA+blood+DCA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool-20:0/20:5-PC+blood+AA+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
TUDCA+stool	MCP-1(MCAF)	TUDCA+stool-UDCA+stool-18:0/20:5-PC+blood+AA+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.241	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tryptophan+stool+18:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Phenylalanine+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+Phenylacetic acid+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool+18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tyrosine+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tryptophan+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool-20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool-16:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Phenylalanine+stool+16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool-16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tyrosine+stool+16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tryptophan+stool+16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool-18:3n3+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-nutriCA+stool-18:3n3+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Phenylalanine+stool+18:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tyrosine+stool+18:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tryptophan+stool+16:1/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Phenylalanine+stool+18:2/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool-18:2/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tyrosine+stool+18:2/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tyrosine+stool+18:1/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool-16:0/18:2-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Phenylalanine+stool+16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool-16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tyrosine+stool+16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tryptophan+stool+16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tryptophan+stool+16:1/16:0-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tyrosine+stool-16:1+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tryptophan+stool+18:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Phenylalanine+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+Phenylacetic acid+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool+18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tyrosine+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tryptophan+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool-20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool-16:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Phenylalanine+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool-16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tyrosine+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tryptophan+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Phenylalanine+stool+18:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tyrosine+stool+18:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tryptophan+stool+16:1/16:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tyrosine+stool+18:1/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool-20:0/20:5-PC+blood+AA+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool-18:0/20:5-PC+blood+AA+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	"Isovaleric acid+stool+L-Phenylalanine+stool+L-Methionine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	"Isovaleric acid+stool+L-Tyrosine+stool+L-Methionine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	"Isovaleric acid+stool+L-Phenylalanine+stool+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	"Isovaleric acid+stool+L-Tyrosine+stool+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	"Isovaleric acid+stool+L-Tryptophan+stool+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	"Isovaleric acid+stool-UDCA+stool+d18:1-16:1-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Phenylalanine+stool+16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool-16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-nutriCA+stool-16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tyrosine+stool+16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool+CDCA+blood+DCA+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool-20:0/20:5-PC+blood-DCA+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-nutriCA+stool+CA+blood+DCA+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+Phenylacetic acid+stool+18:2n6c+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool-18:2n6c+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-nutriCA+stool-18:2n6c+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tyrosine+stool-16:1+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-UDCA+stool-18:0/20:5-PC+blood+Betaine+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tyrosine+stool-18:1/18:1-PE+blood-Betaine+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool+L-Tyrosine+stool-16:1+blood-Betaine+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	DM-LS
Paraprevotella	MCP-1(MCAF)	Paraprevotella+Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.118	0.0633	no	no	no	dn	no	up	DM-LS
iso-LCA+blood	MCP-1(MCAF)	"iso-LCA+blood+L-Ornithine+blood+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	serum_bileacids	serum_cytokines	0.507	0.0633	no	no	no	dn	no	up	DM-LS
Phenylacetic acid+stool	MCP-1(MCAF)	Phenylacetic acid+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0633	no	no	no	dn	no	up	DM-LS
Phenylacetic acid+stool	MCP-1(MCAF)	Phenylacetic acid+stool+18:2n6c+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0633	no	no	no	dn	no	up	DM-LS
Phenylacetic acid+stool	MCP-1(MCAF)	Phenylacetic acid+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0633	no	no	no	dn	no	up	DM-LS
Gemmiger	MCP-1(MCAF)	Gemmiger-18:1-LPC+blood+Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-LS
Gemmiger	MCP-1(MCAF)	Gemmiger-GCA+stool+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-LS
Gemmiger	MCP-1(MCAF)	Gemmiger-GCA+stool+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	DM-LS
GDCA+stool	MCP-1(MCAF)	GDCA+stool+TCA+stool+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.656	0.0633	no	no	no	dn	no	up	DM-LS
GDCA+stool	MCP-1(MCAF)	GDCA+stool+TCA+stool+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.656	0.0633	no	no	no	dn	no	up	DM-LS
Methanobrevibacter	MCP-1(MCAF)	Methanobrevibacter+18:2n6c+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.629	0.0633	no	no	no	dn	no	up	DM-LS
Methanobrevibacter	MCP-1(MCAF)	Methanobrevibacter+18:3n3+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.629	0.0633	no	no	no	dn	no	up	DM-LS
Methanobrevibacter	MCP-1(MCAF)	Methanobrevibacter+18:0-LPC+blood+Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.629	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+18:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+18:1/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool-18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+18:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+18:1/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+18:2/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool-18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool-16:1+blood-Betaine+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool-18:1/18:1-PE+blood-Betaine+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool-16:1+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool-16:1+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	"L-Tyrosine+stool+L-Methionine+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
L-Tyrosine+stool	MCP-1(MCAF)	"L-Tyrosine+stool+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	DM-LS
CDCA+stool	MCP-1(MCAF)	CDCA+stool-16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.663	0.0633	no	no	no	dn	no	up	DM-LS
CDCA+stool	MCP-1(MCAF)	CDCA+stool-20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.663	0.0633	no	no	no	dn	no	up	DM-LS
CDCA+stool	MCP-1(MCAF)	CDCA+stool+18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.663	0.0633	no	no	no	dn	no	up	DM-LS
CDCA+stool	MCP-1(MCAF)	CDCA+stool+TCA+stool+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.663	0.0633	no	no	no	dn	no	up	DM-LS
CDCA+stool	MCP-1(MCAF)	CDCA+stool-16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.663	0.0633	no	no	no	dn	no	up	DM-LS
CDCA+stool	MCP-1(MCAF)	CDCA+stool-20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.663	0.0633	no	no	no	dn	no	up	DM-LS
CDCA+stool	MCP-1(MCAF)	CDCA+stool+18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.663	0.0633	no	no	no	dn	no	up	DM-LS
CDCA+stool	MCP-1(MCAF)	CDCA+stool-16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.663	0.0633	no	no	no	dn	no	up	DM-LS
CDCA+stool	MCP-1(MCAF)	CDCA+stool+TCA+stool+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.663	0.0633	no	no	no	dn	no	up	DM-LS
CA+stool	MCP-1(MCAF)	CA+stool-18:0/20:5-PC+blood+AA+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	DM-LS
CA+stool	MCP-1(MCAF)	CA+stool-20:0/20:5-PC+blood+AA+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	DM-LS
CA+stool	MCP-1(MCAF)	CA+stool+CA+blood+DCA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	DM-LS
CA+stool	MCP-1(MCAF)	CA+stool+CDCA+blood+DCA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	DM-LS
CA+stool	MCP-1(MCAF)	CA+stool-20:0/20:5-PC+blood-DCA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	DM-LS
CA+stool	MCP-1(MCAF)	CA+stool-16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	DM-LS
CA+stool	MCP-1(MCAF)	CA+stool+18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	DM-LS
CA+stool	MCP-1(MCAF)	CA+stool-16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	DM-LS
CA+stool	MCP-1(MCAF)	CA+stool+18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	DM-LS
CA+stool	MCP-1(MCAF)	CA+stool-18:0/20:5-PC+blood+Betaine+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	DM-LS
CA+stool	MCP-1(MCAF)	CA+stool+TCA+stool+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	DM-LS
CA+stool	MCP-1(MCAF)	CA+stool-16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	DM-LS
CA+stool	MCP-1(MCAF)	CA+stool+TCA+stool+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	DM-LS
Slackia	MCP-1(MCAF)	Slackia+MCP-1(MCAF)	Direct	Genus	serum_cytokines	0.94	0.0633	no	no	no	dn	no	up	DM-LS
HDCA+blood	MCP-1(MCAF)	"HDCA+blood+L-Ornithine+blood+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	serum_bileacids	serum_cytokines	0.483	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool-18:2n6c+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool-18:0/20:5-PC+blood+Betaine+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool-16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool-16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool-16:0/18:2-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool+18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool-18:2/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool-16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool-16:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool-18:3n3+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool-20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool+18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool-16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool-16:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool-20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	"UDCA+stool+d18:1-16:1-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool-20:0/20:5-PC+blood-DCA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool+CDCA+blood+DCA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool-20:0/20:5-PC+blood+AA+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
UDCA+stool	MCP-1(MCAF)	UDCA+stool-18:0/20:5-PC+blood+AA+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool-18:2n6c+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool-18:0/20:5-PC+blood+Betaine+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool-16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool-16:0/22:6-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool-16:0/18:2-PC+blood+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool+18:3n6+blood+d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool-18:2/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool-16:0/22:6-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool-16:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool-18:3n3+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool-20:5/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool+18:3n6+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool-16:0/22:6-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool-16:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool-20:5/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	"TDCA+stool+UDCA+stool+d18:1-16:1-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool-20:0/20:5-PC+blood-DCA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool+CDCA+blood+DCA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool-20:0/20:5-PC+blood+AA+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
TDCA+stool	MCP-1(MCAF)	TDCA+stool+UDCA+stool-18:0/20:5-PC+blood+AA+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.963	0.0633	no	no	no	dn	no	up	DM-LS
nutriCA+stool	MCP-1(MCAF)	nutriCA+stool-18:2n6c+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.481	0.0633	no	no	no	dn	no	up	DM-LS
nutriCA+stool	MCP-1(MCAF)	nutriCA+stool+CA+blood+DCA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.481	0.0633	no	no	no	dn	no	up	DM-LS
nutriCA+stool	MCP-1(MCAF)	nutriCA+stool-16:0/16:0-PC+blood+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.481	0.0633	no	no	no	dn	no	up	DM-LS
nutriCA+stool	MCP-1(MCAF)	nutriCA+stool-18:3n3+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.481	0.0633	no	no	no	dn	no	up	DM-LS
GDCA+blood	MCP-1(MCAF)	"GDCA+blood+iso-LCA+blood+L-Ornithine+blood+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-MCP-1(MCAF)"	Indirect	serum_bileacids	serum_cytokines	0.632	0.0633	no	no	no	dn	no	up	DM-LS
GDCA+blood	MCP-1(MCAF)	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.632	0.0633	no	no	no	dn	no	up	DM-LS
acetic acid C2+blood	MCP-1(MCAF)	acetic acid C2+blood+capric acid C6+blood-DCA+blood+MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.000193	0.0633	up	dn	no	dn	no	up	DM-LS
acetic acid C2+blood	MCP-1(MCAF)	acetic acid C2+blood-d18:1-14:1-SM+blood+d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.000193	0.0633	up	dn	no	dn	no	up	DM-LS
isovaleric acid iso-C5+blood	MCP-1(MCAF)	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF-MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.117	0.0633	no	no	no	dn	no	up	DM-LS
Adlercreutzia	MCP-1(MCAF)	Adlercreutzia-14:0+blood-Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.548	0.0633	no	no	no	dn	no	up	DM-LS
Adlercreutzia	MCP-1(MCAF)	Adlercreutzia+18:0-LPC+blood+Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.548	0.0633	no	no	no	dn	no	up	DM-LS
Adlercreutzia	MCP-1(MCAF)	Adlercreutzia+18:1-LPC+blood+Betaine+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.548	0.0633	no	no	no	dn	no	up	DM-LS
Adlercreutzia	MCP-1(MCAF)	Adlercreutzia-14:0+blood+16:0/16:1-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.548	0.0633	no	no	no	dn	no	up	DM-LS
Clostridium	MCP-1(MCAF)	Clostridium+20:4-LPC+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.925	0.0633	no	no	no	dn	no	up	DM-LS
T-¦Á-MCA+stool	MCP-1(MCAF)	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.48	0.0633	no	no	no	dn	no	up	DM-LS
T-¦Á-MCA+stool	MCP-1(MCAF)	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.48	0.0633	no	no	no	dn	no	up	DM-LS
12-ketoDCA+blood	MCP-1(MCAF)	12-ketoDCA+blood-20:4-LPC+blood-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.517	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus-18:0/18:2-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus-18:2/16:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus-18:1/18:0-PC+blood-d18:0-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Phagosome+Adherens junction-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Phagosome+Apoptosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus-18:0/18:2-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus-18:1/18:0-PC+blood-d18:1-16:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Viral myocarditis+Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Cell adhesion molecules+Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Phagosome+Fluid shear stress and atherosclerosis-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Butyric acid+stool+AA+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Cell adhesion molecules+Leukocyte transendothelial migration-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Phagosome+Leukocyte transendothelial migration-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Cell adhesion molecules+Influenza A-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Type I diabetes mellitus+Influenza A-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Phagosome+Influenza A-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Cell adhesion molecules+Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Type I diabetes mellitus+Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Phagosome+Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Natural killer cell mediated cytotoxicity+Pathogenic Escherichia coli infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Cell adhesion molecules+Yersinia infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Type I diabetes mellitus+Yersinia infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus+Phagosome+Yersinia infection-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	DM-LS
Blautia	RANTES	Blautia-L-Ornithine+blood-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	DM-LS
Parabacteroides	RANTES	Parabacteroides+Valine+blood-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	DM-LS
Parabacteroides	RANTES	Parabacteroides+L-Tyrosine+blood-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	DM-LS
Parabacteroides	RANTES	Parabacteroides+L-Phenylalanine+blood-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	DM-LS
Parabacteroides	RANTES	Parabacteroides+L-Leucine+blood-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	DM-LS
Parabacteroides	RANTES	Parabacteroides+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	DM-LS
Dorea	RANTES	Dorea+PDGF-bb+RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	DM-LS
Faecalibacterium	RANTES	Faecalibacterium-Cysteine+blood-RANTES	Indirect	Genus	serum_cytokines	0.0039	0.0757	no	dn	dn	no	no	up	DM-LS
TUDCA+blood	RANTES	TUDCA+blood+Eotaxin+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.0282	0.0757	no	no	dn	no	no	up	DM-LS
TUDCA+blood	RANTES	TUDCA+blood+Eotaxin-GM-CSF-RANTES	Indirect	serum_bileacids	serum_cytokines	0.0282	0.0757	no	no	dn	no	no	up	DM-LS
isocapric acid iso-C6+blood	RANTES	isocapric acid iso-C6+blood-TMAO+blood-MIP-1b+RANTES	Indirect	serum_scfa	serum_cytokines	0.0458	0.0757	no	no	dn	no	no	up	DM-LS
Bacteroides	RANTES	Bacteroides+TMAO+blood-MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.000267	0.0757	dn	dn	up	no	no	up	DM-LS
Bacteroides	RANTES	Bacteroides-GCA+stool+MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.000267	0.0757	dn	dn	up	no	no	up	DM-LS
Bacteroides	RANTES	Bacteroides+3-(3-Hydroxyphenyl)propanoic acid+stool-18:3/18:2-PC+blood+RANTES	Indirect	Genus	serum_cytokines	0.000267	0.0757	dn	dn	up	no	no	up	DM-LS
Bacteroides	RANTES	Bacteroides+22:6n3+blood+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.000267	0.0757	dn	dn	up	no	no	up	DM-LS
Bacteroides	RANTES	Bacteroides+22:6n3+blood+L-Aspartic acid+blood-RANTES	Indirect	Genus	serum_cytokines	0.000267	0.0757	dn	dn	up	no	no	up	DM-LS
Propionic acid+stool	RANTES	Propionic acid+stool+RANTES	Direct	stool_scfa	serum_cytokines	0.0436	0.0757	dn	no	up	no	no	up	DM-LS
5-Hydroxyindole-3-acetic Acid+urine	RANTES	5-Hydroxyindole-3-acetic Acid+urine-IL-9+MIP-1b+RANTES	Indirect	urine_cometabolism	serum_cytokines	0.0405	0.0757	no	dn	dn	no	no	up	DM-LS
[Ruminococcus]	RANTES	[Ruminococcus]-SFA%+blood-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	DM-LS
GUDCA+blood	RANTES	GUDCA+blood-LCA+blood+TMAO+blood-MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0757	no	no	dn	no	no	up	DM-LS
Acetic acid+stool	RANTES	Acetic acid+stool+Propionic acid+stool+RANTES	Indirect	stool_scfa	serum_cytokines	0.0656	0.0757	dn	no	no	no	no	up	DM-LS
Acetic acid+stool	RANTES	Acetic acid+stool-Cysteine+blood-RANTES	Indirect	stool_scfa	serum_cytokines	0.0656	0.0757	dn	no	no	no	no	up	DM-LS
Alistipes	RANTES	Alistipes-L-Aspartic acid+blood-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	DM-LS
Butyricimonas	RANTES	Butyricimonas-Prion disease+RANTES	Indirect	Genus	serum_cytokines	0.17	0.0757	no	no	no	no	no	up	DM-LS
Butyricimonas	RANTES	Butyricimonas-Cardiac muscle contraction+RANTES	Indirect	Genus	serum_cytokines	0.17	0.0757	no	no	no	no	no	up	DM-LS
Butyricimonas	RANTES	Butyricimonas+L-Histidine+blood-RANTES	Indirect	Genus	serum_cytokines	0.17	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Insulin resistance+20:1+blood-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-NF-kappa B signaling pathway-Prion disease+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Prolactin signaling pathway-Prion disease+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-AGE-RAGE signaling pathway in diabetic complications-Prion disease+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-NF-kappa B signaling pathway+iso-DCA+blood-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-18:0+blood+iso-DCA+blood-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-NF-kappa B signaling pathway-Huntington disease+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Prolactin signaling pathway-Huntington disease+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella+Parkinson disease+Huntington disease+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-AGE-RAGE signaling pathway in diabetic complications-Huntington disease+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Neurotrophin signaling pathway-18:3/18:2-PC+blood+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-DHA+blood+DPA+blood-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Hepatitis B+18:0-LPE+blood+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Wnt signaling pathway+Retrograde endocannabinoid signaling+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-RNA degradation+Retrograde endocannabinoid signaling+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Long-term potentiation+Retrograde endocannabinoid signaling+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Phosphatidylinositol signaling system+Retrograde endocannabinoid signaling+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Colorectal cancer-SFA%+blood-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Breast cancer-SFA%+blood-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-LCA+stool-SFA%+blood-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-ErbB signaling pathway-SFA%+blood-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Wnt signaling pathway+Alzheimer disease+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-RNA degradation+Alzheimer disease+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Long-term potentiation+Alzheimer disease+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-NF-kappa B signaling pathway-Alzheimer disease+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Prolactin signaling pathway-Alzheimer disease+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Wnt signaling pathway+Amyotrophic lateral sclerosis+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-NF-kappa B signaling pathway-Amyotrophic lateral sclerosis+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Prolactin signaling pathway-Amyotrophic lateral sclerosis+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella+Parkinson disease+Amyotrophic lateral sclerosis+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-AGE-RAGE signaling pathway in diabetic complications-Amyotrophic lateral sclerosis+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Wnt signaling pathway+CA+blood+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Phosphatidylinositol signaling system+CA+blood+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-RNA degradation-Lysosome-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Phosphatidylinositol signaling system-Lysosome-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Wnt signaling pathway+Diabetic cardiomyopathy+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-NF-kappa B signaling pathway-Diabetic cardiomyopathy+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Wnt signaling pathway-IL-17 signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Signaling pathways regulating pluripotency of stem cells-IL-17 signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-RNA degradation-IL-17 signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-NF-kappa B signaling pathway+IL-17 signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Phosphatidylinositol signaling system-IL-17 signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Glioma-L-Aspartic acid+blood-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-18:0+blood+L-Aspartic acid+blood-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-EPA+blood+L-Aspartic acid+blood-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-Long-term potentiation-L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella+20:1-LPA+blood+L-Histidine+blood-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
Collinsella	RANTES	Collinsella-LCA+stool-Serine+blood-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	DM-LS
total_blood_scfa+blood	RANTES	total_blood_scfa+blood+TUDCA+blood+Eotaxin+MIP-1b+RANTES	Indirect	serum_scfa	serum_cytokines	0.168	0.0757	no	no	no	no	no	up	DM-LS
total_blood_scfa+blood	RANTES	total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF-RANTES	Indirect	serum_scfa	serum_cytokines	0.168	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]-Viral myocarditis-L-Phenylalanine+stool-RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]-Phagosome-L-Phenylalanine+stool-RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]-Viral myocarditis-L-Ornithine+blood-RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]-Viral myocarditis-L-Tyrosine+stool-RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]-Phagosome-L-Tyrosine+stool-RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]+p53 signaling pathway-IL-17 signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]-Phagosome+IL-17 signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]-Yersinia infection-MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]-Fluid shear stress and atherosclerosis-MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]-Pathogenic Escherichia coli infection-MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]-Salmonella infection-MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]-Influenza A-MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]-Phagosome-MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]-Viral myocarditis-L-Tyrosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]-Salmonella infection-L-Tyrosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]+p53 signaling pathway-Lysosome-RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]-Viral myocarditis-Valine+blood-RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
[Eubacterium]	RANTES	[Eubacterium]-Salmonella infection-L-Phenylalanine+blood-RANTES	Indirect	Genus	serum_cytokines	0.0692	0.0757	no	no	no	no	no	up	DM-LS
LCA+stool	RANTES	LCA+stool-SFA%+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.314	0.0757	no	no	no	no	no	up	DM-LS
LCA+stool	RANTES	LCA+stool-Serine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.314	0.0757	no	no	no	no	no	up	DM-LS
Akkermansia	RANTES	Akkermansia-Retrograde endocannabinoid signaling+RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	DM-LS
Akkermansia	RANTES	Akkermansia-MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	DM-LS
Bifidobacterium	RANTES	Bifidobacterium+d18:1-18:1-SM+blood-L-Ornithine+blood-RANTES	Indirect	Genus	serum_cytokines	0.105	0.0757	no	dn	no	no	no	up	DM-LS
Bifidobacterium	RANTES	Bifidobacterium+Glycine+blood+L-Aspartic acid+blood-RANTES	Indirect	Genus	serum_cytokines	0.105	0.0757	no	dn	no	no	no	up	DM-LS
Bifidobacterium	RANTES	Bifidobacterium+Glycine+blood+SFA%+blood-RANTES	Indirect	Genus	serum_cytokines	0.105	0.0757	no	dn	no	no	no	up	DM-LS
Bifidobacterium	RANTES	Bifidobacterium+Glycine+blood+Serine+blood-RANTES	Indirect	Genus	serum_cytokines	0.105	0.0757	no	dn	no	no	no	up	DM-LS
3-Hydroxytyramine hydrochloride+urine	RANTES	3-Hydroxytyramine hydrochloride+urine+L-Phenylalanine+urine+L-Tryptophan+urine+PDGF-bb+RANTES	Indirect	urine_cometabolism	serum_cytokines	0.288	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Cell adhesion molecules-Valine+blood-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Cell adhesion molecules-L-Tyrosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Cell adhesion molecules-L-Phenylalanine+blood-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Type I diabetes mellitus-L-Ornithine+blood-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Allograft rejection-L-Ornithine+blood-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Graft-versus-host disease-L-Ornithine+blood-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Cell adhesion molecules-L-Ornithine+blood-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Autoimmune thyroid disease-L-Ornithine+blood-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Type I diabetes mellitus+Sarcosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Allograft rejection+Sarcosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus-L-Homocystine+blood-Sarcosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Graft-versus-host disease+Sarcosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Autoimmune thyroid disease+Sarcosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+22:6n3+blood+L-Aspartic acid+blood-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+22:6n3+blood+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus-18:2/18:2-PC+blood+18:3/18:2-PC+blood+RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus-18:2/18:1-PC+blood+18:3/18:2-PC+blood+RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Phagosome+IL-17 signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Phagosome-MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Type I diabetes mellitus-L-Phenylalanine+stool-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Natural killer cell mediated cytotoxicity-L-Phenylalanine+stool-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Endocytosis-L-Phenylalanine+stool-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Allograft rejection-L-Phenylalanine+stool-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Graft-versus-host disease-L-Phenylalanine+stool-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Phagosome-L-Phenylalanine+stool-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Cell adhesion molecules-L-Phenylalanine+stool-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Autoimmune thyroid disease-L-Phenylalanine+stool-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Type I diabetes mellitus-L-Tyrosine+stool-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Natural killer cell mediated cytotoxicity-L-Tyrosine+stool-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Endocytosis-L-Tyrosine+stool-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Allograft rejection-L-Tyrosine+stool-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Graft-versus-host disease-L-Tyrosine+stool-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Phagosome-L-Tyrosine+stool-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Cell adhesion molecules-L-Tyrosine+stool-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
Ruminococcus	RANTES	Ruminococcus+Autoimmune thyroid disease-L-Tyrosine+stool-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	DM-LS
GCDCA+blood	RANTES	GCDCA+blood+GUDCA+blood-LCA+blood+TMAO+blood-MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.31	0.0757	no	no	no	no	no	up	DM-LS
GCDCA+blood	RANTES	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.31	0.0757	no	no	no	no	no	up	DM-LS
GCDCA+blood	RANTES	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF-RANTES	Indirect	serum_bileacids	serum_cytokines	0.31	0.0757	no	no	no	no	no	up	DM-LS
Succinivibrio	RANTES	Succinivibrio-L-Tyrosine+stool-RANTES	Indirect	Genus	serum_cytokines	0.138	0.0757	no	no	no	no	no	up	DM-LS
Succinivibrio	RANTES	Succinivibrio-L-Phenylalanine+stool-RANTES	Indirect	Genus	serum_cytokines	0.138	0.0757	no	no	no	no	no	up	DM-LS
ACA+blood	RANTES	ACA+blood-Eotaxin+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.338	0.0757	no	no	no	no	no	up	DM-LS
ACA+blood	RANTES	ACA+blood-DL-methionine sulfoxide+blood+L-Isoleucine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.338	0.0757	no	no	no	no	no	up	DM-LS
ACA+blood	RANTES	ACA+blood+Glycine+blood+Serine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.338	0.0757	no	no	no	no	no	up	DM-LS
ACA+blood	RANTES	ACA+blood-DL-methionine sulfoxide+blood+L-Phenylalanine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.338	0.0757	no	no	no	no	no	up	DM-LS
ACA+blood	RANTES	ACA+blood+Glycine+blood+SFA%+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.338	0.0757	no	no	no	no	no	up	DM-LS
ACA+blood	RANTES	ACA+blood-Eotaxin-GM-CSF-RANTES	Indirect	serum_bileacids	serum_cytokines	0.338	0.0757	no	no	no	no	no	up	DM-LS
ACA+blood	RANTES	ACA+blood-DL-methionine sulfoxide+blood+L-Tyrosine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.338	0.0757	no	no	no	no	no	up	DM-LS
ACA+blood	RANTES	ACA+blood+Glycine+blood+L-Aspartic acid+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.338	0.0757	no	no	no	no	no	up	DM-LS
DCA+stool	RANTES	DCA+stool-Serine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.195	0.0757	no	no	no	no	no	up	DM-LS
DCA+stool	RANTES	DCA+stool+Propionic acid+stool+RANTES	Indirect	stool_bileacids	serum_cytokines	0.195	0.0757	no	no	no	no	no	up	DM-LS
DCA+stool	RANTES	DCA+stool-SFA%+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.195	0.0757	no	no	no	no	no	up	DM-LS
2-hydroxyhippuric acid+urine	RANTES	2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PDGF-bb+RANTES	Indirect	urine_cometabolism	serum_cytokines	0.215	0.0757	no	no	no	no	no	up	DM-LS
Butyric acid+stool	RANTES	Butyric acid+stool+Propionic acid+stool+RANTES	Indirect	stool_scfa	serum_cytokines	0.102	0.0757	dn	no	no	no	no	up	DM-LS
Butyric acid+stool	RANTES	Butyric acid+stool+PDGF-bb+RANTES	Indirect	stool_scfa	serum_cytokines	0.102	0.0757	dn	no	no	no	no	up	DM-LS
4-hydroxybenzoic acid+stool	RANTES	4-hydroxybenzoic acid+stool+SFA%+blood-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.0757	no	dn	no	no	no	up	DM-LS
GCA+blood	RANTES	GCA+blood+GDCA+blood-MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.16	0.0757	no	no	no	no	no	up	DM-LS
ACA+stool	RANTES	ACA+stool+Sarcosine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.417	0.0757	no	no	no	no	no	up	DM-LS
CDCA+blood	RANTES	CDCA+blood-Cysteine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.506	0.0757	no	no	no	no	no	up	DM-LS
capric acid C6+blood	RANTES	capric acid C6+blood-Sarcosine+blood-RANTES	Indirect	serum_scfa	serum_cytokines	0.433	0.0757	no	no	no	no	no	up	DM-LS
Pyramidobacter	RANTES	Pyramidobacter-Lysosome-RANTES	Indirect	Genus	serum_cytokines	0.45	0.0757	no	no	no	no	no	up	DM-LS
Prevotella	RANTES	Prevotella+PDGF-bb+RANTES	Indirect	Genus	serum_cytokines	0.287	0.0757	no	no	no	no	no	up	DM-LS
Prevotella	RANTES	Prevotella+L-Tyrosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.287	0.0757	no	no	no	no	no	up	DM-LS
Prevotella	RANTES	Prevotella+L-Leucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.287	0.0757	no	no	no	no	no	up	DM-LS
TCA+blood	RANTES	TCA+blood+TUDCA+blood+Eotaxin+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.339	0.0757	no	no	no	no	no	up	DM-LS
TCA+blood	RANTES	TCA+blood+TUDCA+blood+Eotaxin-GM-CSF-RANTES	Indirect	serum_bileacids	serum_cytokines	0.339	0.0757	no	no	no	no	no	up	DM-LS
iso-DCA+blood	RANTES	iso-DCA+blood-RANTES	Direct	serum_bileacids	serum_cytokines	0.38	0.0757	no	no	no	no	no	up	DM-LS
HCA+stool	RANTES	HCA+stool-Cysteine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	DM-LS
Roseburia	RANTES	Roseburia-Valine+blood-RANTES	Indirect	Genus	serum_cytokines	0.495	0.0757	no	no	no	no	no	up	DM-LS
Roseburia	RANTES	Roseburia-20:1+blood-RANTES	Indirect	Genus	serum_cytokines	0.495	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+20:4/18:0-PE+blood-Valine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+16:0/22:6-PE+blood-L-Aspartic acid+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+18:1/18:1-PE+blood-L-Aspartic acid+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool-Glycine+blood+L-Aspartic acid+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+18:0/18:1-PE+blood-L-Aspartic acid+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+20:4/18:0-PE+blood-L-Aspartic acid+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+16:0/22:6-PE+blood-L-Ornithine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+18:1/18:1-PE+blood-L-Ornithine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+20:4/18:0-PE+blood-L-Ornithine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+DCA+stool+Propionic acid+stool+RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+DCA+stool-SFA%+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool-Glycine+blood+SFA%+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+LCA+stool-SFA%+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+18:0/18:1-PE+blood-SFA%+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+DCA+stool-Serine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+18:1/18:1-PE+blood-Serine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool-Glycine+blood+Serine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+LCA+stool-Serine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+18:0/18:1-PE+blood-Serine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+18:1/18:1-PE+blood-L-Histidine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool-L-Alanine+blood+PDGF-bb+RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+iso-LCA+stool-Sarcosine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool-L-Alanine+blood+Sarcosine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+16:0/22:6-PE+blood-20:1+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+stool	RANTES	12-ketoDCA+stool+18:0/22:6-PE+blood-20:1+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	DM-LS
4-Hydroxyphenylacetic acid+urine	RANTES	4-Hydroxyphenylacetic acid+urine-5-Hydroxyindole-3-acetic Acid+urine-IL-9+MIP-1b+RANTES	Indirect	urine_cometabolism	serum_cytokines	0.0321	0.0757	up	up	no	no	no	up	DM-LS
GLCA+blood	RANTES	GLCA+blood-Sarcosine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.319	0.0757	no	no	no	no	no	up	DM-LS
L-Tryptophan+stool	RANTES	L-Tryptophan+stool+L-Tyrosine+stool-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0757	no	no	no	no	no	up	DM-LS
L-Tryptophan+stool	RANTES	L-Tryptophan+stool+L-Ornithine+blood-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0757	no	no	no	no	no	up	DM-LS
L-Tryptophan+stool	RANTES	L-Tryptophan+stool+L-Tyrosine+blood-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0757	no	no	no	no	no	up	DM-LS
CA+blood	RANTES	CA+blood+RANTES	Direct	serum_bileacids	serum_cytokines	0.606	0.0757	no	no	no	no	no	up	DM-LS
L-Phenylalanine+stool	RANTES	L-Phenylalanine+stool-RANTES	Direct	stool_cometabolism	serum_cytokines	0.398	0.0757	no	no	no	no	no	up	DM-LS
butyric acid C4+blood	RANTES	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood+SFA%+blood-RANTES	Indirect	serum_scfa	serum_cytokines	0.407	0.0757	no	no	no	no	no	up	DM-LS
butyric acid C4+blood	RANTES	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood+Serine+blood-RANTES	Indirect	serum_scfa	serum_cytokines	0.407	0.0757	no	no	no	no	no	up	DM-LS
butyric acid C4+blood	RANTES	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-MIP-1b+RANTES	Indirect	serum_scfa	serum_cytokines	0.407	0.0757	no	no	no	no	no	up	DM-LS
GCA+stool	RANTES	GCA+stool+MIP-1b+RANTES	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0757	no	no	no	no	no	up	DM-LS
T-a-MCA+blood	RANTES	T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF-RANTES	Indirect	serum_bileacids	serum_cytokines	0.478	0.0757	no	no	no	no	no	up	DM-LS
T-a-MCA+blood	RANTES	T-a-MCA+blood+UFA%+blood-Eotaxin+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.478	0.0757	no	no	no	no	no	up	DM-LS
Coprococcus	RANTES	Coprococcus-CA+blood+RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	DM-LS
Oscillospira	RANTES	Oscillospira+iso-DCA+blood-RANTES	Indirect	Genus	serum_cytokines	0.62	0.0757	no	no	no	no	no	up	DM-LS
Oscillospira	RANTES	Oscillospira+L-Phenylalanine+blood-RANTES	Indirect	Genus	serum_cytokines	0.62	0.0757	no	no	no	no	no	up	DM-LS
Oscillospira	RANTES	Oscillospira+Valine+blood-RANTES	Indirect	Genus	serum_cytokines	0.62	0.0757	no	no	no	no	no	up	DM-LS
Oscillospira	RANTES	Oscillospira-Alzheimer disease+RANTES	Indirect	Genus	serum_cytokines	0.62	0.0757	no	no	no	no	no	up	DM-LS
HCA+blood	RANTES	HCA+blood-MUFA+blood-PDGF-bb+RANTES	Indirect	serum_bileacids	serum_cytokines	0.544	0.0757	no	no	no	no	no	up	DM-LS
iso-LCA+stool	RANTES	iso-LCA+stool-Sarcosine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.72	0.0757	no	no	no	no	no	up	DM-LS
2-methyl-butyric acid m-C4+blood	RANTES	2-methyl-butyric acid m-C4+blood-CA+blood+RANTES	Indirect	serum_scfa	serum_cytokines	0.262	0.0757	no	no	no	no	no	up	DM-LS
DCA+blood	RANTES	DCA+blood-L-Glutamine+blood+L-Histidine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	DM-LS
DCA+blood	RANTES	DCA+blood-MUFA%+blood-MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	DM-LS
DCA+blood	RANTES	DCA+blood+EPA+blood+L-Aspartic acid+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	DM-LS
DCA+blood	RANTES	DCA+blood-L-Glutamine+blood+L-Isoleucine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	DM-LS
DCA+blood	RANTES	DCA+blood-L-Glutamine+blood+Serine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	DM-LS
DCA+blood	RANTES	DCA+blood-MUFA%+blood+Serine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	DM-LS
DCA+blood	RANTES	DCA+blood-L-Glutamine+blood+SFA%+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	DM-LS
DCA+blood	RANTES	DCA+blood-MUFA%+blood+SFA%+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	RANTES	3-(3-Hydroxyphenyl)propanoic acid+stool-18:3/18:2-PC+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0757	no	no	no	no	no	up	DM-LS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	RANTES	"3-(3,4-dihydroxyphenyl)propionic acid+urine+L-Phenylalanine+urine+L-Tryptophan+urine+PDGF-bb+RANTES"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.0757	up	up	no	no	no	up	DM-LS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	RANTES	"3-(3,4-dihydroxyphenyl)propionic acid+urine+3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine+PDGF-bb+RANTES"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.0757	up	up	no	no	no	up	DM-LS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	RANTES	"3-(3,4-dihydroxyphenyl)propionic acid+urine-5-Hydroxyindole-3-acetic Acid+urine-IL-9+MIP-1b+RANTES"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.0757	up	up	no	no	no	up	DM-LS
Indole-3-Acetic acid+stool	RANTES	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0757	no	no	no	no	no	up	DM-LS
Indole-3-Acetic acid+stool	RANTES	Indole-3-Acetic acid+stool+L-Tyrosine+stool-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool-Ethanolamine+blood+L-Tyrosine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool+18:0/18:0-PC+blood+Serine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool+16:0/18:1-PC+blood+Cysteine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool+18:0/16:0-PC+blood+Cysteine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool+16:0/18:1-PC+blood+SFA%+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool+18:1/18:1-PC+blood+SFA%+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool+16:0/20:3-PC+blood+SFA%+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool-Ethanolamine+blood+L-Leucine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool-Ethanolamine+blood+L-Isoleucine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool-Ethanolamine+blood+L-Histidine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool-Ethanolamine+blood+L-Phenylalanine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool+18:0/18:0-PC+blood+20:1+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool-16:0/20:5-PC+blood-20:1+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool+18:0/18:1-PC+blood+20:1+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool-Ethanolamine+blood+Valine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool-16:0/20:5-PC+blood+CA+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool+18:1/18:1-PC+blood+Sarcosine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool+16:0/20:3-PC+blood+Sarcosine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool+16:0/20:3-PC+blood+iso-DCA+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
TCA+stool	RANTES	TCA+stool-L-Tryptophan+urine+PDGF-bb+RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool-18:1/20:3-PC+blood-CA+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool-nutriCA+stool+CA+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool-20:1-LPA+blood+L-Histidine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool+LCA+stool-Serine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	"HDCA+stool+12,13-EPOME+blood+DPA+blood-RANTES"	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool-16:0-LPC+blood+PDGF-bb+RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool-18:1-LPC+blood+18:3/18:2-PC+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool-18:2-LPC+blood+18:3/18:2-PC+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool+HDCA+blood-MIP-1b+RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool+EPA+blood+L-Aspartic acid+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool-18:1-LPC+blood-L-Tyrosine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool+HDCA+blood+L-Ornithine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool-16:0/20:3-PC+blood+SFA%+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool-18:1/18:1-PC+blood+SFA%+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool+LCA+stool-SFA%+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool+HDCA+blood-Sarcosine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool+iso-LCA+stool-Sarcosine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool-16:0/20:3-PC+blood+Sarcosine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool-18:1/18:1-PC+blood+Sarcosine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool-20:2/18:0-PC+blood+Sarcosine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool-18:0/20:3-PC+blood+Sarcosine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
HDCA+stool	RANTES	HDCA+stool-16:0/20:3-PC+blood+iso-DCA+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+18:1/20:3-PC+blood-CA+blood+RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+16:0/18:2-PC+blood+Cysteine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+18:0/18:2-PC+blood+Cysteine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+18:1/16:0-PC+blood+Cysteine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira-Adherens junction+Amyotrophic lateral sclerosis+RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+18:0+blood+L-Aspartic acid+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira-Adherens junction+Alzheimer disease+RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira-d18:1-16:1-SM+blood-L-Ornithine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira-d18:1-14:0-SM+blood-L-Ornithine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira-d18:1-16:1-SM+blood-L-Histidine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira-d18:1-14:0-SM+blood-L-Histidine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+16:0/18:2-PC+blood+L-Histidine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+Choline+blood+L-Histidine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+18:1/16:0-PC+blood+L-Histidine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira-Adherens junction+Diabetic cardiomyopathy+RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+Choline+blood+L-Phenylalanine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+Choline+blood+Valine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira-d18:1-16:1-SM+blood-SFA%+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+18:1/18:0-PC+blood+SFA%+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+18:1/18:1-PC+blood+SFA%+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+16:0/18:2-PC+blood+SFA%+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+18:0/18:2-PC+blood+SFA%+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+18:1/16:0-PC+blood+SFA%+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+16:0/20:3-PC+blood+SFA%+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira-3-(3-Hydroxyphenyl)propanoic acid+stool-18:3/18:2-PC+blood+RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira-Adherens junction+Huntington disease+RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira-Adherens junction+Non-alcoholic fatty liver disease+RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira-Adherens junction+Prion disease+RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira-Adherens junction+Retrograde endocannabinoid signaling+RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+Choline+blood+L-Tyrosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+18:1/18:0-PC+blood+iso-DCA+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira-d18:1-14:0-SM+blood-iso-DCA+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira-Adherens junction-iso-DCA+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+16:0/18:2-PC+blood+iso-DCA+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+18:0+blood+iso-DCA+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+18:0/18:2-PC+blood+iso-DCA+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+Choline+blood+iso-DCA+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+18:1/16:0-PC+blood+iso-DCA+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+20:3/16:0-PC+blood+iso-DCA+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+16:0/20:3-PC+blood+iso-DCA+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+18:1/18:0-PC+blood+Serine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira-d18:1-14:0-SM+blood-Serine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+16:0/18:2-PC+blood+Serine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+18:0/18:2-PC+blood+Serine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+18:1/16:0-PC+blood+Serine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+18:1/18:1-PC+blood+Sarcosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+16:0/20:3-PC+blood+Sarcosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira-d18:1-16:1-SM+blood-L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Lachnospira	RANTES	Lachnospira+Choline+blood+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	DM-LS
Fusobacterium	RANTES	Fusobacterium+SFA%+blood-RANTES	Indirect	Genus	serum_cytokines	0.628	0.0757	no	no	no	no	no	up	DM-LS
isobutyric acid C4+blood	RANTES	isobutyric acid C4+blood+MUFA%+blood+SFA%+blood-RANTES	Indirect	serum_scfa	serum_cytokines	0.0151	0.0757	up	up	no	no	no	up	DM-LS
isobutyric acid C4+blood	RANTES	isobutyric acid C4+blood+MUFA%+blood+Serine+blood-RANTES	Indirect	serum_scfa	serum_cytokines	0.0151	0.0757	up	up	no	no	no	up	DM-LS
isobutyric acid C4+blood	RANTES	isobutyric acid C4+blood+MUFA%+blood-MIP-1b+RANTES	Indirect	serum_scfa	serum_cytokines	0.0151	0.0757	up	up	no	no	no	up	DM-LS
GCDCA+stool	RANTES	GCDCA+stool-L-Isoleucine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	DM-LS
GCDCA+stool	RANTES	GCDCA+stool-L-Histidine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	DM-LS
GCDCA+stool	RANTES	GCDCA+stool-L-Phenylalanine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	DM-LS
GCDCA+stool	RANTES	GCDCA+stool+MIP-1b+RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	DM-LS
GCDCA+stool	RANTES	GCDCA+stool+CA+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	DM-LS
5-Hydroxytryptamine+stool	RANTES	5-Hydroxytryptamine+stool-Propionic acid+stool+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0757	dn	dn	no	no	no	up	DM-LS
5-Hydroxytryptamine+stool	RANTES	5-Hydroxytryptamine+stool+L-Phenylalanine+stool-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0757	dn	dn	no	no	no	up	DM-LS
5-Hydroxytryptamine+stool	RANTES	5-Hydroxytryptamine+stool+L-Tyrosine+stool-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0757	dn	dn	no	no	no	up	DM-LS
Odoribacter	RANTES	Odoribacter+Ethanolamine+blood+L-Leucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-LS
Odoribacter	RANTES	Odoribacter+Choline+blood+Valine+blood-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-LS
Odoribacter	RANTES	Odoribacter+Ethanolamine+blood+Valine+blood-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-LS
Odoribacter	RANTES	Odoribacter+DHA+blood+DPA+blood-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-LS
Odoribacter	RANTES	Odoribacter+Choline+blood+L-Phenylalanine+blood-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-LS
Odoribacter	RANTES	Odoribacter+Ethanolamine+blood+L-Phenylalanine+blood-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-LS
Odoribacter	RANTES	Odoribacter+Choline+blood+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-LS
Odoribacter	RANTES	Odoribacter+Ethanolamine+blood+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-LS
Odoribacter	RANTES	Odoribacter+Choline+blood+L-Histidine+blood-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-LS
Odoribacter	RANTES	Odoribacter+Ethanolamine+blood+L-Histidine+blood-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-LS
Odoribacter	RANTES	Odoribacter+Choline+blood+iso-DCA+blood-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-LS
Odoribacter	RANTES	Odoribacter+Choline+blood+L-Tyrosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-LS
Odoribacter	RANTES	Odoribacter+Ethanolamine+blood+L-Tyrosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-LS
Odoribacter	RANTES	Odoribacter-14:0/16:0-PC+blood+Sarcosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-LS
Odoribacter	RANTES	Odoribacter+IL-8-MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-LS
Odoribacter	RANTES	Odoribacter-14:0/16:0-PC+blood+MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-LS
Odoribacter	RANTES	Odoribacter-L-2-Aminobutyric acid+blood+Serine+blood-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	DM-LS
Isobutyric acid+stool	RANTES	Isobutyric acid+stool+L-Tyrosine+stool-RANTES	Indirect	stool_scfa	serum_cytokines	0.408	0.0757	no	no	no	no	no	up	DM-LS
Isobutyric acid+stool	RANTES	Isobutyric acid+stool+L-Phenylalanine+stool-RANTES	Indirect	stool_scfa	serum_cytokines	0.408	0.0757	no	no	no	no	no	up	DM-LS
2-hydroxyphenylacetic acid+urine	RANTES	2-hydroxyphenylacetic acid+urine-L-Tryptophan+urine+PDGF-bb+RANTES	Indirect	urine_cometabolism	serum_cytokines	0.763	0.0757	no	no	no	no	no	up	DM-LS
Lachnobacterium	RANTES	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF-RANTES	Indirect	Genus	serum_cytokines	0.867	0.0757	no	no	no	no	no	up	DM-LS
Lachnobacterium	RANTES	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin+MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.867	0.0757	no	no	no	no	no	up	DM-LS
Kynurenic acid+stool	RANTES	Kynurenic acid+stool+L-Tyrosine+stool-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0757	dn	dn	no	no	no	up	DM-LS
L-Tryptophan+urine	RANTES	L-Tryptophan+urine+PDGF-bb+RANTES	Indirect	urine_cometabolism	serum_cytokines	0.226	0.0757	no	no	no	no	no	up	DM-LS
Anaerostipes	RANTES	Anaerostipes-L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.568	0.0757	no	no	no	no	no	up	DM-LS
TUDCA+stool	RANTES	TUDCA+stool-UDCA+stool-L-Ornithine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.241	0.0757	no	no	no	no	no	up	DM-LS
Isovaleric acid+stool	RANTES	Isovaleric acid+stool+L-Phenylalanine+stool-RANTES	Indirect	stool_scfa	serum_cytokines	0.343	0.0757	no	no	no	no	no	up	DM-LS
Isovaleric acid+stool	RANTES	Isovaleric acid+stool+L-Tyrosine+stool-RANTES	Indirect	stool_scfa	serum_cytokines	0.343	0.0757	no	no	no	no	no	up	DM-LS
Paraprevotella	RANTES	Paraprevotella+Betaine+blood+L-Ornithine+blood-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-LS
Paraprevotella	RANTES	Paraprevotella+Betaine+blood+Serine+blood-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-LS
Paraprevotella	RANTES	Paraprevotella+Betaine+blood+Valine+blood-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-LS
Paraprevotella	RANTES	Paraprevotella+18:0/20:2-PC+blood+18:3/18:2-PC+blood+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-LS
Paraprevotella	RANTES	Paraprevotella+18:0/20:2-PC+blood+20:1+blood-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-LS
Paraprevotella	RANTES	Paraprevotella+Betaine+blood+L-Isoleucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-LS
Paraprevotella	RANTES	Paraprevotella+Betaine+blood+L-Histidine+blood-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-LS
Paraprevotella	RANTES	Paraprevotella+Betaine+blood-CA+blood+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-LS
Paraprevotella	RANTES	Paraprevotella+d18:1-20:0-SM+blood+PDGF-bb+RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-LS
Paraprevotella	RANTES	Paraprevotella+Betaine+blood+L-Aspartic acid+blood-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	DM-LS
DL-Indole-3-lactic acid+urine	RANTES	DL-Indole-3-lactic acid+urine+L-Phenylalanine+urine+L-Tryptophan+urine+PDGF-bb+RANTES	Indirect	urine_cometabolism	serum_cytokines	0.00552	0.0757	up	up	no	no	no	up	DM-LS
iso-LCA+blood	RANTES	iso-LCA+blood-Sarcosine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.507	0.0757	no	no	no	no	no	up	DM-LS
iso-LCA+blood	RANTES	iso-LCA+blood+L-Ornithine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.507	0.0757	no	no	no	no	no	up	DM-LS
Phenylacetic acid+stool	RANTES	Phenylacetic acid+stool+Cysteine+blood-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0757	no	no	no	no	no	up	DM-LS
Phenylacetic acid+stool	RANTES	Phenylacetic acid+stool-Sarcosine+blood-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0757	no	no	no	no	no	up	DM-LS
Gemmiger	RANTES	Gemmiger+L-Tyrosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.595	0.0757	no	no	no	no	no	up	DM-LS
Gemmiger	RANTES	Gemmiger+L-Phenylalanine+blood-RANTES	Indirect	Genus	serum_cytokines	0.595	0.0757	no	no	no	no	no	up	DM-LS
GDCA+stool	RANTES	GDCA+stool-L-Histidine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.656	0.0757	no	no	no	no	no	up	DM-LS
GDCA+stool	RANTES	GDCA+stool-L-Phenylalanine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.656	0.0757	no	no	no	no	no	up	DM-LS
GDCA+stool	RANTES	GDCA+stool-L-Isoleucine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.656	0.0757	no	no	no	no	no	up	DM-LS
GDCA+stool	RANTES	GDCA+stool+MIP-1b+RANTES	Indirect	stool_bileacids	serum_cytokines	0.656	0.0757	no	no	no	no	no	up	DM-LS
GDCA+stool	RANTES	GDCA+stool-Propionic acid+stool+RANTES	Indirect	stool_bileacids	serum_cytokines	0.656	0.0757	no	no	no	no	no	up	DM-LS
Methanobrevibacter	RANTES	Methanobrevibacter+Valine+blood-RANTES	Indirect	Genus	serum_cytokines	0.629	0.0757	no	no	no	no	no	up	DM-LS
Methanobrevibacter	RANTES	Methanobrevibacter-Sarcosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.629	0.0757	no	no	no	no	no	up	DM-LS
Methanobrevibacter	RANTES	Methanobrevibacter+L-Tyrosine+stool-RANTES	Indirect	Genus	serum_cytokines	0.629	0.0757	no	no	no	no	no	up	DM-LS
Methanobrevibacter	RANTES	Methanobrevibacter+L-Phenylalanine+stool-RANTES	Indirect	Genus	serum_cytokines	0.629	0.0757	no	no	no	no	no	up	DM-LS
Methanobrevibacter	RANTES	Methanobrevibacter+L-Leucine+blood-RANTES	Indirect	Genus	serum_cytokines	0.629	0.0757	no	no	no	no	no	up	DM-LS
L-Tyrosine+stool	RANTES	L-Tyrosine+stool-RANTES	Direct	stool_cometabolism	serum_cytokines	0.44	0.0757	no	no	no	no	no	up	DM-LS
CDCA+stool	RANTES	CDCA+stool-L-Phenylalanine+stool-RANTES	Indirect	stool_bileacids	serum_cytokines	0.663	0.0757	no	no	no	no	no	up	DM-LS
CDCA+stool	RANTES	CDCA+stool-L-Ornithine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.663	0.0757	no	no	no	no	no	up	DM-LS
CDCA+stool	RANTES	CDCA+stool-L-Tyrosine+stool-RANTES	Indirect	stool_bileacids	serum_cytokines	0.663	0.0757	no	no	no	no	no	up	DM-LS
CA+stool	RANTES	CA+stool+CA+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.827	0.0757	no	no	no	no	no	up	DM-LS
CA+stool	RANTES	CA+stool-L-Ornithine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.827	0.0757	no	no	no	no	no	up	DM-LS
CA+stool	RANTES	CA+stool-L-Phenylalanine+stool-RANTES	Indirect	stool_bileacids	serum_cytokines	0.827	0.0757	no	no	no	no	no	up	DM-LS
CA+stool	RANTES	CA+stool-L-Tyrosine+stool-RANTES	Indirect	stool_bileacids	serum_cytokines	0.827	0.0757	no	no	no	no	no	up	DM-LS
Slackia	RANTES	Slackia-Arginine and proline metabolism-RANTES	Indirect	Genus	serum_cytokines	0.94	0.0757	no	no	no	no	no	up	DM-LS
Slackia	RANTES	Slackia-Serine+blood-RANTES	Indirect	Genus	serum_cytokines	0.94	0.0757	no	no	no	no	no	up	DM-LS
Slackia	RANTES	Slackia-Cysteine+blood-RANTES	Indirect	Genus	serum_cytokines	0.94	0.0757	no	no	no	no	no	up	DM-LS
HDCA+blood	RANTES	HDCA+blood-Sarcosine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.483	0.0757	no	no	no	no	no	up	DM-LS
HDCA+blood	RANTES	HDCA+blood+L-Ornithine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.483	0.0757	no	no	no	no	no	up	DM-LS
HDCA+blood	RANTES	HDCA+blood-MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.483	0.0757	no	no	no	no	no	up	DM-LS
UDCA+stool	RANTES	UDCA+stool-L-Ornithine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.266	0.0757	no	no	no	no	no	up	DM-LS
TDCA+stool	RANTES	TDCA+stool+UDCA+stool-L-Ornithine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.963	0.0757	no	no	no	no	no	up	DM-LS
LCA+blood	RANTES	LCA+blood+TMAO+blood-MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.884	0.0757	no	no	no	no	no	up	DM-LS
nutriCA+stool	RANTES	nutriCA+stool+CA+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.481	0.0757	no	no	no	no	no	up	DM-LS
GDCA+blood	RANTES	GDCA+blood-MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.632	0.0757	no	no	no	no	no	up	DM-LS
acetic acid C2+blood	RANTES	acetic acid C2+blood-Sarcosine+blood-RANTES	Indirect	serum_scfa	serum_cytokines	0.000193	0.0757	up	dn	no	no	no	up	DM-LS
isovaleric acid iso-C5+blood	RANTES	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+MIP-1b+RANTES	Indirect	serum_scfa	serum_cytokines	0.117	0.0757	no	no	no	no	no	up	DM-LS
isovaleric acid iso-C5+blood	RANTES	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF-RANTES	Indirect	serum_scfa	serum_cytokines	0.117	0.0757	no	no	no	no	no	up	DM-LS
L-Phenylalanine+urine	RANTES	L-Phenylalanine+urine+L-Tryptophan+urine+PDGF-bb+RANTES	Indirect	urine_cometabolism	serum_cytokines	0.0908	0.0757	no	up	no	no	no	up	DM-LS
Adlercreutzia	RANTES	Adlercreutzia+18:1-LPC+blood-L-Tyrosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.548	0.0757	no	no	no	no	no	up	DM-LS
Adlercreutzia	RANTES	Adlercreutzia+18:0-LPC+blood+20:1+blood-RANTES	Indirect	Genus	serum_cytokines	0.548	0.0757	no	no	no	no	no	up	DM-LS
Adlercreutzia	RANTES	Adlercreutzia-16:0/20:5-PC+blood-20:1+blood-RANTES	Indirect	Genus	serum_cytokines	0.548	0.0757	no	no	no	no	no	up	DM-LS
Adlercreutzia	RANTES	Adlercreutzia-EPA+blood+L-Aspartic acid+blood-RANTES	Indirect	Genus	serum_cytokines	0.548	0.0757	no	no	no	no	no	up	DM-LS
Adlercreutzia	RANTES	Adlercreutzia+18:0-LPC+blood+PDGF-bb+RANTES	Indirect	Genus	serum_cytokines	0.548	0.0757	no	no	no	no	no	up	DM-LS
Adlercreutzia	RANTES	Adlercreutzia-14:0+blood-Serine+blood-RANTES	Indirect	Genus	serum_cytokines	0.548	0.0757	no	no	no	no	no	up	DM-LS
Adlercreutzia	RANTES	Adlercreutzia-16:0/20:5-PC+blood+CA+blood+RANTES	Indirect	Genus	serum_cytokines	0.548	0.0757	no	no	no	no	no	up	DM-LS
Adlercreutzia	RANTES	Adlercreutzia+16:0/18:0-PC+blood-DPA+blood-RANTES	Indirect	Genus	serum_cytokines	0.548	0.0757	no	no	no	no	no	up	DM-LS
Adlercreutzia	RANTES	Adlercreutzia-3-(3-Hydroxyphenyl)propanoic acid+stool-18:3/18:2-PC+blood+RANTES	Indirect	Genus	serum_cytokines	0.548	0.0757	no	no	no	no	no	up	DM-LS
Adlercreutzia	RANTES	Adlercreutzia+18:0-LPC+blood+18:3/18:2-PC+blood+RANTES	Indirect	Genus	serum_cytokines	0.548	0.0757	no	no	no	no	no	up	DM-LS
Adlercreutzia	RANTES	Adlercreutzia+18:2-LPC+blood+18:3/18:2-PC+blood+RANTES	Indirect	Genus	serum_cytokines	0.548	0.0757	no	no	no	no	no	up	DM-LS
Adlercreutzia	RANTES	Adlercreutzia+16:0/18:0-PC+blood+18:3/18:2-PC+blood+RANTES	Indirect	Genus	serum_cytokines	0.548	0.0757	no	no	no	no	no	up	DM-LS
Adlercreutzia	RANTES	Adlercreutzia+18:1-LPC+blood+18:3/18:2-PC+blood+RANTES	Indirect	Genus	serum_cytokines	0.548	0.0757	no	no	no	no	no	up	DM-LS
Adlercreutzia	RANTES	Adlercreutzia+18:0-LPC+blood+18:0-LPE+blood+RANTES	Indirect	Genus	serum_cytokines	0.548	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium+PUFA/MUFA+blood+SFA%+blood-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-14:0/20:4-PC+blood-SFA%+blood-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-18:0/20:2-PC+blood+18:3/18:2-PC+blood+RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-14:0/20:4-PC+blood+18:3/18:2-PC+blood+RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-14:0/16:0-PC+blood+MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-14:0/20:4-PC+blood+MIP-1b+RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-14:0/16:0-PC+blood+Sarcosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium+cGMP-PKG signaling pathway+IL-17 signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium+cGMP-PKG signaling pathway+Lysosome-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-Butyric acid+stool+PDGF-bb+RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
 Clostridium	RANTES	Clostridium+Butyric acid+stool+PDGF-bb+RANTES	Indirect	Genus	serum_cytokines	NA	0.0757	NA	NA	NA	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-Butyric acid+stool+PDGF-bb+RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
 Clostridium	RANTES	Clostridium+Butyric acid+stool+PDGF-bb+RANTES	Indirect	Genus	serum_cytokines	NA	0.0757	NA	NA	NA	no	no	up	DM-LS
Clostridium	RANTES	Clostridium+CDCA+blood-Cysteine+blood-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-14:0/20:4-PC+blood-Cysteine+blood-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-Acetic acid+stool-Cysteine+blood-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
 Clostridium	RANTES	Clostridium+Acetic acid+stool-Cysteine+blood-RANTES	Indirect	Genus	serum_cytokines	NA	0.0757	NA	NA	NA	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-Acetic acid+stool-Cysteine+blood-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
 Clostridium	RANTES	Clostridium+Acetic acid+stool-Cysteine+blood-RANTES	Indirect	Genus	serum_cytokines	NA	0.0757	NA	NA	NA	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-18:0/20:2-PC+blood+20:1+blood-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-Butyric acid+stool+Propionic acid+stool+RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
 Clostridium	RANTES	Clostridium+Butyric acid+stool+Propionic acid+stool+RANTES	Indirect	Genus	serum_cytokines	NA	0.0757	NA	NA	NA	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-Butyric acid+stool+Propionic acid+stool+RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
 Clostridium	RANTES	Clostridium+Butyric acid+stool+Propionic acid+stool+RANTES	Indirect	Genus	serum_cytokines	NA	0.0757	NA	NA	NA	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-Acetic acid+stool+Propionic acid+stool+RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
 Clostridium	RANTES	Clostridium+Acetic acid+stool+Propionic acid+stool+RANTES	Indirect	Genus	serum_cytokines	NA	0.0757	NA	NA	NA	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-Acetic acid+stool+Propionic acid+stool+RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
 Clostridium	RANTES	Clostridium+Acetic acid+stool+Propionic acid+stool+RANTES	Indirect	Genus	serum_cytokines	NA	0.0757	NA	NA	NA	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-14:0/20:4-PC+blood-Serine+blood-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-14:0/18:2-PC+blood-Serine+blood-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-14:0/20:4-PC+blood-L-Ornithine+blood-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-14:0/20:4-PC+blood-L-Histidine+blood-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium-14:0/18:2-PC+blood-L-Histidine+blood-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium+20:1-LPA+blood+L-Histidine+blood-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
Clostridium	RANTES	Clostridium+d18:1-24:1-SM+blood-L-Tyrosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
 Clostridium	RANTES	Clostridium-d18:1-24:1-SM+blood-L-Tyrosine+blood-RANTES	Indirect	Genus	serum_cytokines	NA	0.0757	NA	NA	NA	no	no	up	DM-LS
Clostridium	RANTES	Clostridium+d18:1-24:1-SM+blood-L-Tyrosine+blood-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	DM-LS
 Clostridium	RANTES	Clostridium-d18:1-24:1-SM+blood-L-Tyrosine+blood-RANTES	Indirect	Genus	serum_cytokines	NA	0.0757	NA	NA	NA	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool-Ethanolamine+blood+L-Tyrosine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool+18:0/18:0-PC+blood+Serine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+Cysteine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+Cysteine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+SFA%+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+SFA%+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+SFA%+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool-Ethanolamine+blood+L-Leucine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool-Ethanolamine+blood+L-Isoleucine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool-Ethanolamine+blood+L-Histidine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool-Ethanolamine+blood+L-Phenylalanine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool+18:0/18:0-PC+blood+20:1+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood-20:1+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool+18:0/18:1-PC+blood+20:1+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool-Ethanolamine+blood+Valine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+CA+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+Sarcosine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+Sarcosine+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+iso-DCA+blood-RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
T-¦Á-MCA+stool	RANTES	T-¦Á-MCA+stool-TCA+stool-L-Tryptophan+urine+PDGF-bb+RANTES	Indirect	stool_bileacids	serum_cytokines	0.48	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-20:3-LPE+blood+Sarcosine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood+GLCA+blood-Sarcosine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-L-Lysine+blood+L-Phenylalanine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-L-Arginine+blood+L-Phenylalanine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-20:3-LPE+blood-L-Ornithine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-L-Lysine+blood+L-Ornithine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-L-Lysine+blood+L-Tyrosine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-L-Lysine+blood+SFA%+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-L-Arginine+blood+SFA%+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-L-Lysine+blood+Serine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-L-Arginine+blood+Serine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-L-Lysine+blood+Valine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-L-Arginine+blood+Valine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-IL-9+MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood+GDCA+blood-MIP-1b+RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-L-Arginine+blood+L-Leucine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-L-Arginine+blood+L-Aspartic acid+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-20:0-LPC+blood+20:1+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-L-Arginine+blood+L-Histidine+blood-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	DM-LS
Butyricicoccus	RANTES	Butyricicoccus-L-Phenylalanine+stool-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	DM-LS
Butyricicoccus	RANTES	Butyricicoccus-L-Tyrosine+stool-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	DM-LS
3-Hydroxy-L-kynurenine+urine	RANTES	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine+PDGF-bb+RANTES	Indirect	urine_cometabolism	serum_cytokines	0.401	0.0757	no	no	no	no	no	up	DM-LS
Blautia	IL-1ra	Blautia-16:0/18:2-PC+blood+20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	DM-LS
Blautia	IL-1ra	Blautia-18:1/16:0-PC+blood+20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	DM-LS
Blautia	IL-1ra	Blautia-18:0/22:6-PC+blood+20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	DM-LS
Blautia	IL-1ra	Blautia-12-ketoDCA+stool+18:0/22:6-PE+blood+IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	DM-LS
Blautia	IL-1ra	Blautia-18:0/22:6-PC+blood+18:0/22:6-PE+blood+IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	DM-LS
Blautia	IL-1ra	Blautia-16:0/22:6-PC+blood+18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	DM-LS
Blautia	IL-1ra	Blautia-16:0/18:2-PC+blood+18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	DM-LS
Parabacteroides	IL-1ra	Parabacteroides-EGFR tyrosine kinase inhibitor resistance+Proteasome-IL-1ra	Indirect	Genus	serum_cytokines	4.19E-05	0.0288	no	up	up	no	up	up	DM-LS
Parabacteroides	IL-1ra	Parabacteroides-Central carbon metabolism in cancer+18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	4.19E-05	0.0288	no	up	up	no	up	up	DM-LS
Parabacteroides	IL-1ra	Parabacteroides-TCA+stool-16:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	4.19E-05	0.0288	no	up	up	no	up	up	DM-LS
Parabacteroides	IL-1ra	Parabacteroides-GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra	Indirect	Genus	serum_cytokines	4.19E-05	0.0288	no	up	up	no	up	up	DM-LS
Parabacteroides	IL-1ra	Parabacteroides-Insulin signaling pathway+L-2-Aminobutyric acid+blood-IL-1ra	Indirect	Genus	serum_cytokines	4.19E-05	0.0288	no	up	up	no	up	up	DM-LS
Parabacteroides	IL-1ra	Parabacteroides-15-HETE+blood-20:1+blood-IL-1ra	Indirect	Genus	serum_cytokines	4.19E-05	0.0288	no	up	up	no	up	up	DM-LS
Dorea	IL-1ra	Dorea-18:0/22:6-PE+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.00362	0.0288	up	no	dn	no	up	up	DM-LS
Faecalibacterium	IL-1ra	Faecalibacterium-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.0039	0.0288	no	dn	dn	no	up	up	DM-LS
TUDCA+blood	IL-1ra	TUDCA+blood+Eotaxin-GM-CSF+IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.0282	0.0288	no	no	dn	no	up	up	DM-LS
TUDCA+blood	IL-1ra	TUDCA+blood+Eotaxin+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.0282	0.0288	no	no	dn	no	up	up	DM-LS
isocapric acid iso-C6+blood	IL-1ra	isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF+IL-1ra	Indirect	serum_scfa	serum_cytokines	0.0458	0.0288	no	no	dn	no	up	up	DM-LS
isocapric acid iso-C6+blood	IL-1ra	isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-17A-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.0458	0.0288	no	no	dn	no	up	up	DM-LS
Bacteroides	IL-1ra	Bacteroides-18:2/20:4-PC+blood+20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.000267	0.0288	dn	dn	up	no	up	up	DM-LS
Bacteroides	IL-1ra	Bacteroides+3-(3-Hydroxyphenyl)propanoic acid+stool-20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.000267	0.0288	dn	dn	up	no	up	up	DM-LS
Bacteroides	IL-1ra	Bacteroides+3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.000267	0.0288	dn	dn	up	no	up	up	DM-LS
Bacteroides	IL-1ra	Bacteroides-GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.000267	0.0288	dn	dn	up	no	up	up	DM-LS
Propionic acid+stool	IL-1ra	Propionic acid+stool+18:0/22:6-PE+blood+IL-1ra	Indirect	stool_scfa	serum_cytokines	0.0436	0.0288	dn	no	up	no	up	up	DM-LS
Propionic acid+stool	IL-1ra	Propionic acid+stool+16:0/20:5-PC+blood+IL-1ra	Indirect	stool_scfa	serum_cytokines	0.0436	0.0288	dn	no	up	no	up	up	DM-LS
[Ruminococcus]	IL-1ra	[Ruminococcus]-FGF basic+IL-17A-IL-1ra	Indirect	Genus	serum_cytokines	0.0679	0.0288	no	no	dn	no	up	up	DM-LS
[Ruminococcus]	IL-1ra	[Ruminococcus]-16:0/18:2-PC+blood+18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.0679	0.0288	no	no	dn	no	up	up	DM-LS
[Ruminococcus]	IL-1ra	[Ruminococcus]-16:0/18:2-PC+blood+20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.0679	0.0288	no	no	dn	no	up	up	DM-LS
[Ruminococcus]	IL-1ra	[Ruminococcus]-18:1/16:0-PC+blood+20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.0679	0.0288	no	no	dn	no	up	up	DM-LS
[Ruminococcus]	IL-1ra	[Ruminococcus]-TCA+stool-16:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.0679	0.0288	no	no	dn	no	up	up	DM-LS
[Ruminococcus]	IL-1ra	[Ruminococcus]-15-HETE+blood-20:1+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.0679	0.0288	no	no	dn	no	up	up	DM-LS
[Ruminococcus]	IL-1ra	[Ruminococcus]+Transcriptional misregulation in cancer+GPC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.0679	0.0288	no	no	dn	no	up	up	DM-LS
GUDCA+blood	IL-1ra	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0288	no	no	dn	no	up	up	DM-LS
GUDCA+blood	IL-1ra	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0288	no	no	dn	no	up	up	DM-LS
Acetic acid+stool	IL-1ra	Acetic acid+stool-Phenylacetic acid+stool-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.0656	0.0288	dn	no	no	no	up	up	DM-LS
Alistipes	IL-1ra	Alistipes+12-ketoDCA+stool+18:0/22:6-PE+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.0114	0.0288	no	up	no	no	up	up	DM-LS
Butyricimonas	IL-1ra	Butyricimonas-Prion disease-18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.17	0.0288	no	no	no	no	up	up	DM-LS
Butyricimonas	IL-1ra	Butyricimonas-Cardiac muscle contraction-18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.17	0.0288	no	no	no	no	up	up	DM-LS
Butyricimonas	IL-1ra	Butyricimonas-Prion disease-20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.17	0.0288	no	no	no	no	up	up	DM-LS
Butyricimonas	IL-1ra	Butyricimonas-Cardiac muscle contraction-20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.17	0.0288	no	no	no	no	up	up	DM-LS
Collinsella	IL-1ra	Collinsella-Central carbon metabolism in cancer+18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.128	0.0288	no	no	no	no	up	up	DM-LS
Collinsella	IL-1ra	Collinsella-Insulin resistance+20:1+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.128	0.0288	no	no	no	no	up	up	DM-LS
Collinsella	IL-1ra	Collinsella-DHA+blood-L-2-Aminobutyric acid+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.128	0.0288	no	no	no	no	up	up	DM-LS
Collinsella	IL-1ra	Collinsella-MAPK signaling pathway-Salivary secretion+IL-1ra	Indirect	Genus	serum_cytokines	0.128	0.0288	no	no	no	no	up	up	DM-LS
Collinsella	IL-1ra	Collinsella-Wnt signaling pathway-Salivary secretion+IL-1ra	Indirect	Genus	serum_cytokines	0.128	0.0288	no	no	no	no	up	up	DM-LS
Collinsella	IL-1ra	Collinsella-RNA degradation-Salivary secretion+IL-1ra	Indirect	Genus	serum_cytokines	0.128	0.0288	no	no	no	no	up	up	DM-LS
Collinsella	IL-1ra	Collinsella-Phosphatidylinositol signaling system-Salivary secretion+IL-1ra	Indirect	Genus	serum_cytokines	0.128	0.0288	no	no	no	no	up	up	DM-LS
Collinsella	IL-1ra	Collinsella-Hepatitis B+GPC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.128	0.0288	no	no	no	no	up	up	DM-LS
Collinsella	IL-1ra	Collinsella-Long-term potentiation-20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.128	0.0288	no	no	no	no	up	up	DM-LS
total_blood_scfa+blood	IL-1ra	total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-1ra	Indirect	serum_scfa	serum_cytokines	0.168	0.0288	no	no	no	no	up	up	DM-LS
total_blood_scfa+blood	IL-1ra	total_blood_scfa+blood+TUDCA+blood+Eotaxin+IL-17A-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.168	0.0288	no	no	no	no	up	up	DM-LS
[Eubacterium]	IL-1ra	[Eubacterium]-Viral myocarditis-L-2-Aminobutyric acid+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.0692	0.0288	no	no	no	no	up	up	DM-LS
[Eubacterium]	IL-1ra	[Eubacterium]-Viral myocarditis-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.0692	0.0288	no	no	no	no	up	up	DM-LS
LCA+stool	IL-1ra	LCA+stool-Cystine+blood+L-2-Aminobutyric acid+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	DM-LS
LCA+stool	IL-1ra	LCA+stool-TCA+stool-16:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	DM-LS
LCA+stool	IL-1ra	LCA+stool-UDCA+stool-20:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	DM-LS
LCA+stool	IL-1ra	LCA+stool-UDCA+stool-18:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	DM-LS
LCA+stool	IL-1ra	LCA+stool-nutriCA+stool-Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	DM-LS
Akkermansia	IL-1ra	Akkermansia+18:0/22:6-PE+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.23	0.0288	no	no	no	no	up	up	DM-LS
Bifidobacterium	IL-1ra	Bifidobacterium-FGF basic+IL-17A-IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-LS
Bifidobacterium	IL-1ra	Bifidobacterium-18:2/20:4-PC+blood+20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	DM-LS
Ruminococcus	IL-1ra	Ruminococcus+Type I diabetes mellitus-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	DM-LS
Ruminococcus	IL-1ra	Ruminococcus+Endocytosis-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	DM-LS
Ruminococcus	IL-1ra	Ruminococcus+Allograft rejection-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	DM-LS
Ruminococcus	IL-1ra	Ruminococcus+Graft-versus-host disease-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	DM-LS
Ruminococcus	IL-1ra	Ruminococcus+Cell adhesion molecules-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	DM-LS
Ruminococcus	IL-1ra	Ruminococcus+Autoimmune thyroid disease-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	DM-LS
Ruminococcus	IL-1ra	Ruminococcus+Cell adhesion molecules-L-2-Aminobutyric acid+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	DM-LS
GCDCA+blood	IL-1ra	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.31	0.0288	no	no	no	no	up	up	DM-LS
GCDCA+blood	IL-1ra	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.31	0.0288	no	no	no	no	up	up	DM-LS
Succinivibrio	IL-1ra	Succinivibrio-L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.138	0.0288	no	no	no	no	up	up	DM-LS
Succinivibrio	IL-1ra	Succinivibrio-L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.138	0.0288	no	no	no	no	up	up	DM-LS
ACA+blood	IL-1ra	ACA+blood-Eotaxin+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.338	0.0288	no	no	no	no	up	up	DM-LS
ACA+blood	IL-1ra	ACA+blood-Eotaxin-GM-CSF+IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.338	0.0288	no	no	no	no	up	up	DM-LS
DCA+stool	IL-1ra	DCA+stool-18:1/18:0-PC+blood+20:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-LS
DCA+stool	IL-1ra	DCA+stool-18:0/18:2-PC+blood+20:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-LS
DCA+stool	IL-1ra	DCA+stool-GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-LS
DCA+stool	IL-1ra	DCA+stool-Cystine+blood+L-2-Aminobutyric acid+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-LS
DCA+stool	IL-1ra	DCA+stool+18:0/18:0-PS+blood+18:0/22:6-PE+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-LS
DCA+stool	IL-1ra	DCA+stool-GDCA+stool-18:0/22:6-PE+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-LS
DCA+stool	IL-1ra	DCA+stool+16:0/18:0-PS+blood+18:0/22:6-PE+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-LS
DCA+stool	IL-1ra	DCA+stool+Propionic acid+stool+18:0/22:6-PE+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-LS
DCA+stool	IL-1ra	DCA+stool+18:0/18:0-PS+blood-18:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-LS
DCA+stool	IL-1ra	DCA+stool+16:0/18:0-PS+blood-18:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-LS
DCA+stool	IL-1ra	DCA+stool-18:0/18:2-PC+blood+18:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-LS
DCA+stool	IL-1ra	DCA+stool+iso-LCA+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-LS
DCA+stool	IL-1ra	DCA+stool-16:0/20:3-PC+blood-16:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-LS
DCA+stool	IL-1ra	DCA+stool+Propionic acid+stool+16:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-LS
DCA+stool	IL-1ra	DCA+stool-TCA+stool-16:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	DM-LS
Butyric acid+stool	IL-1ra	Butyric acid+stool-Phenylacetic acid+stool-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.102	0.0288	dn	no	no	no	up	up	DM-LS
4-hydroxybenzoic acid+stool	IL-1ra	4-hydroxybenzoic acid+stool-Phenylacetic acid+stool-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.0288	no	dn	no	no	up	up	DM-LS
GCA+blood	IL-1ra	GCA+blood+FGF basic+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.16	0.0288	no	no	no	no	up	up	DM-LS
ACA+stool	IL-1ra	ACA+stool+GPC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.417	0.0288	no	no	no	no	up	up	DM-LS
CDCA+blood	IL-1ra	CDCA+blood-Cysteine+blood+L-2-Aminobutyric acid+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.506	0.0288	no	no	no	no	up	up	DM-LS
capric acid C6+blood	IL-1ra	capric acid C6+blood-CDCA+blood-Cysteine+blood+L-2-Aminobutyric acid+blood-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.433	0.0288	no	no	no	no	up	up	DM-LS
capric acid C6+blood	IL-1ra	capric acid C6+blood+UFA%+blood-Eotaxin+IL-17A-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.433	0.0288	no	no	no	no	up	up	DM-LS
capric acid C6+blood	IL-1ra	capric acid C6+blood+TUDCA+blood+Eotaxin+IL-17A-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.433	0.0288	no	no	no	no	up	up	DM-LS
capric acid C6+blood	IL-1ra	capric acid C6+blood+MUFA%+blood-Eotaxin+IL-17A-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.433	0.0288	no	no	no	no	up	up	DM-LS
capric acid C6+blood	IL-1ra	capric acid C6+blood-Sarcosine+blood-FGF basic+IL-17A-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.433	0.0288	no	no	no	no	up	up	DM-LS
capric acid C6+blood	IL-1ra	capric acid C6+blood-L-Alanine+blood-FGF basic+IL-17A-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.433	0.0288	no	no	no	no	up	up	DM-LS
capric acid C6+blood	IL-1ra	capric acid C6+blood-d18:1-16:1-SM+blood+d18:1-20:0-SM+blood+GPC+blood+IL-1ra	Indirect	serum_scfa	serum_cytokines	0.433	0.0288	no	no	no	no	up	up	DM-LS
capric acid C6+blood	IL-1ra	capric acid C6+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1ra	Indirect	serum_scfa	serum_cytokines	0.433	0.0288	no	no	no	no	up	up	DM-LS
capric acid C6+blood	IL-1ra	capric acid C6+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-1ra	Indirect	serum_scfa	serum_cytokines	0.433	0.0288	no	no	no	no	up	up	DM-LS
capric acid C6+blood	IL-1ra	capric acid C6+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1ra	Indirect	serum_scfa	serum_cytokines	0.433	0.0288	no	no	no	no	up	up	DM-LS
Pyramidobacter	IL-1ra	Pyramidobacter+Insulin resistance+20:1+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.45	0.0288	no	no	no	no	up	up	DM-LS
Pyramidobacter	IL-1ra	"Pyramidobacter+Parathyroid hormone synthesis, secretion and action+Salivary secretion+IL-1ra"	Indirect	Genus	serum_cytokines	0.45	0.0288	no	no	no	no	up	up	DM-LS
Pyramidobacter	IL-1ra	Pyramidobacter-Carbon metabolism+18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.45	0.0288	no	no	no	no	up	up	DM-LS
Pyramidobacter	IL-1ra	Pyramidobacter+Pathways in cancer+Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.45	0.0288	no	no	no	no	up	up	DM-LS
Prevotella	IL-1ra	Prevotella-Proteasome-IL-1ra	Indirect	Genus	serum_cytokines	0.287	0.0288	no	no	no	no	up	up	DM-LS
TCA+blood	IL-1ra	TCA+blood+FGF basic+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.339	0.0288	no	no	no	no	up	up	DM-LS
iso-DCA+blood	IL-1ra	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.38	0.0288	no	no	no	no	up	up	DM-LS
iso-DCA+blood	IL-1ra	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.38	0.0288	no	no	no	no	up	up	DM-LS
iso-DCA+blood	IL-1ra	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.38	0.0288	no	no	no	no	up	up	DM-LS
iso-DCA+blood	IL-1ra	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin-GM-CSF+IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.38	0.0288	no	no	no	no	up	up	DM-LS
iso-DCA+blood	IL-1ra	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.38	0.0288	no	no	no	no	up	up	DM-LS
iso-DCA+blood	IL-1ra	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.38	0.0288	no	no	no	no	up	up	DM-LS
HCA+stool	IL-1ra	HCA+stool-18:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.155	0.0288	no	no	no	no	up	up	DM-LS
HCA+stool	IL-1ra	HCA+stool-GPC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.155	0.0288	no	no	no	no	up	up	DM-LS
Roseburia	IL-1ra	Roseburia-20:1+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.495	0.0288	no	no	no	no	up	up	DM-LS
12-ketoDCA+stool	IL-1ra	12-ketoDCA+stool+18:0/22:6-PE+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.505	0.0288	no	no	no	no	up	up	DM-LS
GLCA+blood	IL-1ra	GLCA+blood-Sarcosine+blood-FGF basic+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.319	0.0288	no	no	no	no	up	up	DM-LS
L-Tryptophan+stool	IL-1ra	L-Tryptophan+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0288	no	no	no	no	up	up	DM-LS
CA+blood	IL-1ra	CA+blood+Eotaxin-GM-CSF+IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.606	0.0288	no	no	no	no	up	up	DM-LS
CA+blood	IL-1ra	CA+blood+Eotaxin+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.606	0.0288	no	no	no	no	up	up	DM-LS
CA+blood	IL-1ra	CA+blood-Cysteine+blood+L-2-Aminobutyric acid+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.606	0.0288	no	no	no	no	up	up	DM-LS
L-Phenylalanine+stool	IL-1ra	L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0288	no	no	no	no	up	up	DM-LS
butyric acid C4+blood	IL-1ra	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin+IL-17A-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.407	0.0288	no	no	no	no	up	up	DM-LS
butyric acid C4+blood	IL-1ra	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1ra	Indirect	serum_scfa	serum_cytokines	0.407	0.0288	no	no	no	no	up	up	DM-LS
GCA+stool	IL-1ra	GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0288	no	no	no	no	up	up	DM-LS
T-a-MCA+blood	IL-1ra	T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.478	0.0288	no	no	no	no	up	up	DM-LS
T-a-MCA+blood	IL-1ra	T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.478	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-TCA+stool-16:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-Eotaxin+IL-17A-IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-Eotaxin-GM-CSF+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-CA+stool-20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus+Peroxisome+20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus+Biosynthesis of amino acids+20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-Melanogenesis-18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-Amphetamine addiction-18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-Aldosterone synthesis and secretion-18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-CA+stool-18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus+Peroxisome+18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-Dopaminergic synapse-18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus+Biosynthesis of amino acids+18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-Morphine addiction-18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus+Peroxisome+18:0/22:6-PE+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus+Butyric acid+stool-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-CA+stool-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus+iso-LCA+stool+Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-CDCA+stool-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-nutriCA+stool-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-Vasopressin-regulated water reabsorption+Salivary secretion+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-Melanogenesis+Salivary secretion+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-Endocrine and other factor-regulated calcium reabsorption+Salivary secretion+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-Aldosterone synthesis and secretion+Salivary secretion+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-Vascular smooth muscle contraction+Salivary secretion+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Coprococcus	IL-1ra	Coprococcus-Circadian entrainment+Salivary secretion+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	DM-LS
Oscillospira	IL-1ra	Oscillospira+Peroxisome+18:0/22:6-PE+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.62	0.0288	no	no	no	no	up	up	DM-LS
Oscillospira	IL-1ra	Oscillospira+Peroxisome+18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.62	0.0288	no	no	no	no	up	up	DM-LS
Oscillospira	IL-1ra	Oscillospira-Alzheimer disease-18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.62	0.0288	no	no	no	no	up	up	DM-LS
Oscillospira	IL-1ra	Oscillospira+Peroxisome+20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.62	0.0288	no	no	no	no	up	up	DM-LS
Oscillospira	IL-1ra	Oscillospira-Alzheimer disease-20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.62	0.0288	no	no	no	no	up	up	DM-LS
Oscillospira	IL-1ra	Oscillospira-CDCA+stool-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.62	0.0288	no	no	no	no	up	up	DM-LS
Oscillospira	IL-1ra	Oscillospira-nutriCA+stool-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.62	0.0288	no	no	no	no	up	up	DM-LS
Oscillospira	IL-1ra	Oscillospira-4-hydroxybenzoic acid+stool-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.62	0.0288	no	no	no	no	up	up	DM-LS
HCA+blood	IL-1ra	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.544	0.0288	no	no	no	no	up	up	DM-LS
HCA+blood	IL-1ra	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.544	0.0288	no	no	no	no	up	up	DM-LS
iso-LCA+stool	IL-1ra	iso-LCA+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.72	0.0288	no	no	no	no	up	up	DM-LS
2-methyl-butyric acid m-C4+blood	IL-1ra	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin-GM-CSF+IL-1ra	Indirect	serum_scfa	serum_cytokines	0.262	0.0288	no	no	no	no	up	up	DM-LS
2-methyl-butyric acid m-C4+blood	IL-1ra	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin+IL-17A-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.262	0.0288	no	no	no	no	up	up	DM-LS
2-methyl-butyric acid m-C4+blood	IL-1ra	2-methyl-butyric acid m-C4+blood-CA+blood-Cysteine+blood+L-2-Aminobutyric acid+blood-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.262	0.0288	no	no	no	no	up	up	DM-LS
DCA+blood	IL-1ra	DCA+blood-MUFA%+blood-Eotaxin+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.122	0.0288	no	no	no	no	up	up	DM-LS
DCA+blood	IL-1ra	DCA+blood-TCA+blood+FGF basic+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.122	0.0288	no	no	no	no	up	up	DM-LS
DCA+blood	IL-1ra	DCA+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.122	0.0288	no	no	no	no	up	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1ra	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/20:5-PC+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0288	no	no	no	no	up	up	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1ra	3-(3-Hydroxyphenyl)propanoic acid+stool-20:0/20:5-PC+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0288	no	no	no	no	up	up	DM-LS
Indole-3-Acetic acid+stool	IL-1ra	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0288	no	no	no	no	up	up	DM-LS
TCA+stool	IL-1ra	TCA+stool-16:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.458	0.0288	no	no	no	no	up	up	DM-LS
HDCA+stool	IL-1ra	HDCA+stool-18:1/20:3-PC+blood+20:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.176	0.0288	no	no	no	no	up	up	DM-LS
HDCA+stool	IL-1ra	HDCA+stool-16:0-LPC+blood+GPC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.176	0.0288	no	no	no	no	up	up	DM-LS
HDCA+stool	IL-1ra	HDCA+stool-nutriCA+stool-Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.176	0.0288	no	no	no	no	up	up	DM-LS
HDCA+stool	IL-1ra	HDCA+stool+iso-LCA+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.176	0.0288	no	no	no	no	up	up	DM-LS
HDCA+stool	IL-1ra	HDCA+stool-16:0/20:3-PC+blood-16:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.176	0.0288	no	no	no	no	up	up	DM-LS
HDCA+stool	IL-1ra	HDCA+stool-16:0-LPC+blood-18:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.176	0.0288	no	no	no	no	up	up	DM-LS
HDCA+stool	IL-1ra	HDCA+stool-18:0-LPA+blood-18:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.176	0.0288	no	no	no	no	up	up	DM-LS
Lachnospira	IL-1ra	Lachnospira+18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.279	0.0288	no	no	no	no	up	up	DM-LS
Lachnospira	IL-1ra	Lachnospira+20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.279	0.0288	no	no	no	no	up	up	DM-LS
Fusobacterium	IL-1ra	Fusobacterium+16:0/20:3-PC+blood-16:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.628	0.0288	no	no	no	no	up	up	DM-LS
Fusobacterium	IL-1ra	Fusobacterium+nutriCA+stool-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.628	0.0288	no	no	no	no	up	up	DM-LS
isobutyric acid C4+blood	IL-1ra	isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1ra	Indirect	serum_scfa	serum_cytokines	0.0151	0.0288	up	up	no	no	up	up	DM-LS
isobutyric acid C4+blood	IL-1ra	isobutyric acid C4+blood+MUFA%+blood-Eotaxin+IL-17A-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.0151	0.0288	up	up	no	no	up	up	DM-LS
GCDCA+stool	IL-1ra	GCDCA+stool+TCA+stool-16:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0288	no	dn	no	no	up	up	DM-LS
GCDCA+stool	IL-1ra	GCDCA+stool+18:0/18:0-PC+blood+20:1+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0288	no	dn	no	no	up	up	DM-LS
GCDCA+stool	IL-1ra	GCDCA+stool+18:0/18:1-PC+blood+20:1+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0288	no	dn	no	no	up	up	DM-LS
GCDCA+stool	IL-1ra	GCDCA+stool+18:0/18:0-PC+blood+L-2-Aminobutyric acid+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0288	no	dn	no	no	up	up	DM-LS
GCDCA+stool	IL-1ra	GCDCA+stool+18:0/18:1-PC+blood+L-2-Aminobutyric acid+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0288	no	dn	no	no	up	up	DM-LS
GCDCA+stool	IL-1ra	GCDCA+stool+GDCA+stool-18:0/22:6-PE+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0288	no	dn	no	no	up	up	DM-LS
5-Hydroxytryptamine+stool	IL-1ra	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0288	dn	dn	no	no	up	up	DM-LS
5-Hydroxytryptamine+stool	IL-1ra	5-Hydroxytryptamine+stool+L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0288	dn	dn	no	no	up	up	DM-LS
5-Hydroxytryptamine+stool	IL-1ra	5-Hydroxytryptamine+stool-Acetic acid+stool-Phenylacetic acid+stool-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0288	dn	dn	no	no	up	up	DM-LS
5-Hydroxytryptamine+stool	IL-1ra	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0288	dn	dn	no	no	up	up	DM-LS
5-Hydroxytryptamine+stool	IL-1ra	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/20:5-PC+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0288	dn	dn	no	no	up	up	DM-LS
5-Hydroxytryptamine+stool	IL-1ra	5-Hydroxytryptamine+stool-Propionic acid+stool+18:0/22:6-PE+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0288	dn	dn	no	no	up	up	DM-LS
Odoribacter	IL-1ra	Odoribacter-L-2-Aminobutyric acid+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	DM-LS
Isobutyric acid+stool	IL-1ra	Isobutyric acid+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.408	0.0288	no	no	no	no	up	up	DM-LS
Lachnobacterium	IL-1ra	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1ra	Indirect	Genus	serum_cytokines	0.867	0.0288	no	no	no	no	up	up	DM-LS
Lachnobacterium	IL-1ra	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-1ra	Indirect	Genus	serum_cytokines	0.867	0.0288	no	no	no	no	up	up	DM-LS
Kynurenic acid+stool	IL-1ra	Kynurenic acid+stool-nutriCA+stool-Phenylacetic acid+stool-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0288	dn	dn	no	no	up	up	DM-LS
Kynurenic acid+stool	IL-1ra	Kynurenic acid+stool+L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0288	dn	dn	no	no	up	up	DM-LS
Kynurenic acid+stool	IL-1ra	Kynurenic acid+stool-UDCA+stool-18:0/20:5-PC+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0288	dn	dn	no	no	up	up	DM-LS
Kynurenic acid+stool	IL-1ra	Kynurenic acid+stool-UDCA+stool-20:0/20:5-PC+blood+IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0288	dn	dn	no	no	up	up	DM-LS
Anaerostipes	IL-1ra	Anaerostipes+15-HETE+blood-20:1+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.568	0.0288	no	no	no	no	up	up	DM-LS
Anaerostipes	IL-1ra	Anaerostipes-Insulin resistance+20:1+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.568	0.0288	no	no	no	no	up	up	DM-LS
Anaerostipes	IL-1ra	Anaerostipes-3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.568	0.0288	no	no	no	no	up	up	DM-LS
Anaerostipes	IL-1ra	Anaerostipes-Hepatitis B+GPC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.568	0.0288	no	no	no	no	up	up	DM-LS
Anaerostipes	IL-1ra	Anaerostipes-3-(3-Hydroxyphenyl)propanoic acid+stool-20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.568	0.0288	no	no	no	no	up	up	DM-LS
TUDCA+stool	IL-1ra	TUDCA+stool-UDCA+stool-20:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.241	0.0288	no	no	no	no	up	up	DM-LS
TUDCA+stool	IL-1ra	TUDCA+stool-UDCA+stool-18:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.241	0.0288	no	no	no	no	up	up	DM-LS
Isovaleric acid+stool	IL-1ra	Isovaleric acid+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.343	0.0288	no	no	no	no	up	up	DM-LS
Paraprevotella	IL-1ra	Paraprevotella+18:0/20:2-PC+blood-18:0/22:6-PE+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-LS
Paraprevotella	IL-1ra	Paraprevotella+18:0/20:2-PC+blood+20:1+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-LS
Paraprevotella	IL-1ra	Paraprevotella+d18:1-20:0-SM+blood+GPC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	DM-LS
iso-LCA+blood	IL-1ra	iso-LCA+blood-Sarcosine+blood-FGF basic+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.507	0.0288	no	no	no	no	up	up	DM-LS
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-IL-1ra	Direct	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	DM-LS
Gemmiger	IL-1ra	Gemmiger-GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-LS
Gemmiger	IL-1ra	Gemmiger+DHA+blood-L-2-Aminobutyric acid+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	DM-LS
GDCA+stool	IL-1ra	GDCA+stool-18:0/22:6-PE+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.656	0.0288	no	no	no	no	up	up	DM-LS
Methanobrevibacter	IL-1ra	Methanobrevibacter+L-2-Aminobutyric acid+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.629	0.0288	no	no	no	no	up	up	DM-LS
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	DM-LS
CDCA+stool	IL-1ra	CDCA+stool-Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.663	0.0288	no	no	no	no	up	up	DM-LS
CA+stool	IL-1ra	CA+stool-Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.827	0.0288	no	no	no	no	up	up	DM-LS
CA+stool	IL-1ra	CA+stool-18:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.827	0.0288	no	no	no	no	up	up	DM-LS
CA+stool	IL-1ra	CA+stool-20:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.827	0.0288	no	no	no	no	up	up	DM-LS
Slackia	IL-1ra	Slackia-16:0/22:6-PE+blood-L-2-Aminobutyric acid+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.94	0.0288	no	no	no	no	up	up	DM-LS
Slackia	IL-1ra	Slackia-Cysteine+blood+L-2-Aminobutyric acid+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.94	0.0288	no	no	no	no	up	up	DM-LS
Slackia	IL-1ra	Slackia-Cystine+blood+L-2-Aminobutyric acid+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.94	0.0288	no	no	no	no	up	up	DM-LS
Slackia	IL-1ra	Slackia-16:0/22:6-PE+blood+18:0/22:6-PE+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.94	0.0288	no	no	no	no	up	up	DM-LS
Slackia	IL-1ra	Slackia+Platinum drug resistance-18:0/22:6-PE+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.94	0.0288	no	no	no	no	up	up	DM-LS
Slackia	IL-1ra	Slackia-cGMP-PKG signaling pathway+18:0/22:6-PE+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.94	0.0288	no	no	no	no	up	up	DM-LS
Slackia	IL-1ra	Slackia-PPAR signaling pathway+18:0/22:6-PE+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.94	0.0288	no	no	no	no	up	up	DM-LS
Slackia	IL-1ra	Slackia-16:0/22:6-PE+blood-20:1+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.94	0.0288	no	no	no	no	up	up	DM-LS
Slackia	IL-1ra	Slackia-15-HETE+blood-20:1+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.94	0.0288	no	no	no	no	up	up	DM-LS
HDCA+blood	IL-1ra	HDCA+blood-Sarcosine+blood-FGF basic+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.483	0.0288	no	no	no	no	up	up	DM-LS
UDCA+stool	IL-1ra	UDCA+stool-20:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.266	0.0288	no	no	no	no	up	up	DM-LS
UDCA+stool	IL-1ra	UDCA+stool-18:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.266	0.0288	no	no	no	no	up	up	DM-LS
TDCA+stool	IL-1ra	TDCA+stool+UDCA+stool-20:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.963	0.0288	no	no	no	no	up	up	DM-LS
TDCA+stool	IL-1ra	TDCA+stool+UDCA+stool-18:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.963	0.0288	no	no	no	no	up	up	DM-LS
nutriCA+stool	IL-1ra	nutriCA+stool-Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.481	0.0288	no	no	no	no	up	up	DM-LS
GDCA+blood	IL-1ra	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.632	0.0288	no	no	no	no	up	up	DM-LS
GDCA+blood	IL-1ra	GDCA+blood+iso-LCA+blood-Sarcosine+blood-FGF basic+IL-17A-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.632	0.0288	no	no	no	no	up	up	DM-LS
GDCA+blood	IL-1ra	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF+IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.632	0.0288	no	no	no	no	up	up	DM-LS
acetic acid C2+blood	IL-1ra	acetic acid C2+blood-L-Alanine+blood-FGF basic+IL-17A-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.000193	0.0288	up	dn	no	no	up	up	DM-LS
acetic acid C2+blood	IL-1ra	acetic acid C2+blood-Sarcosine+blood-FGF basic+IL-17A-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.000193	0.0288	up	dn	no	no	up	up	DM-LS
acetic acid C2+blood	IL-1ra	acetic acid C2+blood-d18:1-14:1-SM+blood-DMG+blood+GPC+blood+IL-1ra	Indirect	serum_scfa	serum_cytokines	0.000193	0.0288	up	dn	no	no	up	up	DM-LS
acetic acid C2+blood	IL-1ra	acetic acid C2+blood-d18:1-14:1-SM+blood+d18:1-20:0-SM+blood+GPC+blood+IL-1ra	Indirect	serum_scfa	serum_cytokines	0.000193	0.0288	up	dn	no	no	up	up	DM-LS
isovaleric acid iso-C5+blood	IL-1ra	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-1ra	Indirect	serum_scfa	serum_cytokines	0.117	0.0288	no	no	no	no	up	up	DM-LS
isovaleric acid iso-C5+blood	IL-1ra	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-17A-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.117	0.0288	no	no	no	no	up	up	DM-LS
Adlercreutzia	IL-1ra	Adlercreutzia-16:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.548	0.0288	no	no	no	no	up	up	DM-LS
Clostridium	IL-1ra	Clostridium-20:0/20:5-PC+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	DM-LS
T-¦Á-MCA+stool	IL-1ra	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.48	0.0288	no	no	no	no	up	up	DM-LS
12-ketoDCA+blood	IL-1ra	12-ketoDCA+blood-20:0-LPC+blood+20:1+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.517	0.0288	no	no	no	no	up	up	DM-LS
Butyricicoccus	IL-1ra	Butyricicoccus-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.852	0.0288	no	no	no	no	up	up	DM-LS
Blautia	Eotaxin	Blautia-20:5/18:0-PC+blood-Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	DM-LS
Parabacteroides	Eotaxin	Parabacteroides-Glucagon signaling pathway+Eotaxin	Indirect	Genus	serum_cytokines	4.19E-05	0.393	no	up	up	no	no	no	DM-LS
Parabacteroides	Eotaxin	Parabacteroides-Spliceosome+Eotaxin	Indirect	Genus	serum_cytokines	4.19E-05	0.393	no	up	up	no	no	no	DM-LS
Parabacteroides	Eotaxin	Parabacteroides+Choline+blood-Eotaxin	Indirect	Genus	serum_cytokines	4.19E-05	0.393	no	up	up	no	no	no	DM-LS
Dorea	Eotaxin	Dorea-Lipid and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.00362	0.393	up	no	dn	no	no	no	DM-LS
Faecalibacterium	Eotaxin	Faecalibacterium-Cysteine+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	DM-LS
TUDCA+blood	Eotaxin	TUDCA+blood+Eotaxin	Direct	serum_bileacids	serum_cytokines	0.0282	0.393	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	Eotaxin	isocapric acid iso-C6+blood-n3+blood-Eotaxin	Indirect	serum_scfa	serum_cytokines	0.0458	0.393	no	no	dn	no	no	no	DM-LS
Bacteroides	Eotaxin	Bacteroides+n3+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-LS
Bacteroides	Eotaxin	Bacteroides+22:6n3+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	DM-LS
Propionic acid+stool	Eotaxin	Propionic acid+stool-UFA%+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.0436	0.393	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	Eotaxin	Propionic acid+stool-MUFA%+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.0436	0.393	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	Eotaxin	Propionic acid+stool-ACA+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.0436	0.393	dn	no	up	no	no	no	DM-LS
[Ruminococcus]	Eotaxin	[Ruminococcus]-UFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.0679	0.393	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	Eotaxin	[Ruminococcus]-20:5/18:0-PC+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.0679	0.393	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	Eotaxin	[Ruminococcus]-MUFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.0679	0.393	no	no	dn	no	no	no	DM-LS
GUDCA+blood	Eotaxin	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.0766	0.393	no	no	dn	no	no	no	DM-LS
Acetic acid+stool	Eotaxin	Acetic acid+stool-UFA%+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.0656	0.393	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	Eotaxin	Acetic acid+stool-Cysteine+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.0656	0.393	dn	no	no	no	no	no	DM-LS
Alistipes	Eotaxin	Alistipes-L-Arginine+blood+UFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.0114	0.393	no	up	no	no	no	no	DM-LS
Alistipes	Eotaxin	Alistipes-HIF-1 signaling pathway+Measles-Eotaxin	Indirect	Genus	serum_cytokines	0.0114	0.393	no	up	no	no	no	no	DM-LS
Alistipes	Eotaxin	Alistipes-L-Aspartic acid+blood+n3+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.0114	0.393	no	up	no	no	no	no	DM-LS
Butyricimonas	Eotaxin	Butyricimonas+20:5/18:0-PC+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.17	0.393	no	no	no	no	no	no	DM-LS
Collinsella	Eotaxin	Collinsella-Signaling pathways regulating pluripotency of stem cells+Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-LS
Collinsella	Eotaxin	Collinsella-Colorectal cancer+Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-LS
Collinsella	Eotaxin	Collinsella-Glioma+Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-LS
Collinsella	Eotaxin	Collinsella-Long-term potentiation+Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-LS
Collinsella	Eotaxin	Collinsella-Choline metabolism in cancer+Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-LS
Collinsella	Eotaxin	Collinsella-Gastric cancer+Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-LS
Collinsella	Eotaxin	Collinsella-ErbB signaling pathway+Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-LS
Collinsella	Eotaxin	Collinsella-Phosphatidylinositol signaling system+Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	Eotaxin	total_blood_scfa+blood+TUDCA+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.168	0.393	no	no	no	no	no	no	DM-LS
[Eubacterium]	Eotaxin	[Eubacterium]-Viral myocarditis-Eotaxin	Indirect	Genus	serum_cytokines	0.0692	0.393	no	no	no	no	no	no	DM-LS
[Eubacterium]	Eotaxin	[Eubacterium]-Pathogenic Escherichia coli infection-Eotaxin	Indirect	Genus	serum_cytokines	0.0692	0.393	no	no	no	no	no	no	DM-LS
[Eubacterium]	Eotaxin	[Eubacterium]-Phagosome-Eotaxin	Indirect	Genus	serum_cytokines	0.0692	0.393	no	no	no	no	no	no	DM-LS
LCA+stool	Eotaxin	LCA+stool-ACA+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia+Apoptosis-Cushing syndrome+Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia+LCA+stool-ACA+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia-4-hydroxybenzoic acid+stool+ACA+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia+Apoptosis+Viral myocarditis-Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia+Apoptosis-Glucagon signaling pathway+Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia+Apoptosis+Fc gamma R-mediated phagocytosis-Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia+Apoptosis-Inflammatory mediator regulation of TRP channels+Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia-18:0/18:2-PI+blood-Creatinine+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia+Apoptosis+IL-17 signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia-18:0/18:2-PI+blood-TUDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia+Apoptosis+Neutrophil extracellular trap formation-Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia+Apoptosis-Melanogenesis+Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia-Retrograde endocannabinoid signaling-20:5/18:0-PC+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia+Apoptosis-Long-term potentiation+Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia+Apoptosis+Lipid and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia+Apoptosis+Pathogenic Escherichia coli infection-Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia+Apoptosis+Systemic lupus erythematosus-Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia-Retrograde endocannabinoid signaling+CA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia+Apoptosis+Staphylococcus aureus infection-Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia+Apoptosis-Aldosterone synthesis and secretion+Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Akkermansia	Eotaxin	Akkermansia+Apoptosis-Adrenergic signaling in cardiomyocytes+Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	DM-LS
Bifidobacterium	Eotaxin	Bifidobacterium+Chemical carcinogenesis - receptor activation+Eotaxin	Indirect	Genus	serum_cytokines	0.105	0.393	no	dn	no	no	no	no	DM-LS
Ruminococcus	Eotaxin	Ruminococcus+Type I diabetes mellitus-Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	DM-LS
Ruminococcus	Eotaxin	Ruminococcus+Endocytosis-Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	DM-LS
Ruminococcus	Eotaxin	Ruminococcus+Allograft rejection-Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	DM-LS
Ruminococcus	Eotaxin	Ruminococcus+22:6n3+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	DM-LS
Ruminococcus	Eotaxin	Ruminococcus+Graft-versus-host disease-Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	DM-LS
Ruminococcus	Eotaxin	Ruminococcus+Phagosome-Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	DM-LS
Ruminococcus	Eotaxin	Ruminococcus+Cell adhesion molecules-Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	DM-LS
Ruminococcus	Eotaxin	Ruminococcus+Autoimmune thyroid disease-Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	DM-LS
GCDCA+blood	Eotaxin	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.31	0.393	no	no	no	no	no	no	DM-LS
Succinivibrio	Eotaxin	Succinivibrio-L-Phenylalanine+stool+n3+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.138	0.393	no	no	no	no	no	no	DM-LS
Succinivibrio	Eotaxin	Succinivibrio-Phospholipase D signaling pathway+Cushing syndrome+Eotaxin	Indirect	Genus	serum_cytokines	0.138	0.393	no	no	no	no	no	no	DM-LS
Succinivibrio	Eotaxin	Succinivibrio-Phospholipase D signaling pathway-MUFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.138	0.393	no	no	no	no	no	no	DM-LS
Succinivibrio	Eotaxin	Succinivibrio-L-Phenylalanine+stool+Cysteine+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.138	0.393	no	no	no	no	no	no	DM-LS
Succinivibrio	Eotaxin	Succinivibrio-Phospholipase D signaling pathway+Chemical carcinogenesis - receptor activation+Eotaxin	Indirect	Genus	serum_cytokines	0.138	0.393	no	no	no	no	no	no	DM-LS
Succinivibrio	Eotaxin	Succinivibrio-L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.138	0.393	no	no	no	no	no	no	DM-LS
Succinivibrio	Eotaxin	Succinivibrio-L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.138	0.393	no	no	no	no	no	no	DM-LS
Succinivibrio	Eotaxin	Succinivibrio-Phospholipase D signaling pathway-UFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.138	0.393	no	no	no	no	no	no	DM-LS
ACA+blood	Eotaxin	ACA+blood-Eotaxin	Direct	serum_bileacids	serum_cytokines	0.338	0.393	no	no	no	no	no	no	DM-LS
DCA+stool	Eotaxin	DCA+stool-UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.195	0.393	no	no	no	no	no	no	DM-LS
DCA+stool	Eotaxin	DCA+stool-ACA+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.195	0.393	no	no	no	no	no	no	DM-LS
Butyric acid+stool	Eotaxin	Butyric acid+stool+Propionic acid+stool-MUFA%+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.102	0.393	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	Eotaxin	Butyric acid+stool+8-HETE+blood-ACA+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.102	0.393	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	Eotaxin	Butyric acid+stool+Propionic acid+stool-ACA+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.102	0.393	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	Eotaxin	Butyric acid+stool-16:1/16:1-PC+blood+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.102	0.393	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	Eotaxin	Butyric acid+stool+AA+blood+Choline+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.102	0.393	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	Eotaxin	Butyric acid+stool+Propionic acid+stool-UFA%+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.102	0.393	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	Eotaxin	Butyric acid+stool-Phenylacetic acid+stool+Cysteine+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.102	0.393	dn	no	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	Eotaxin	4-hydroxybenzoic acid+stool+ACA+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.393	no	dn	no	no	no	no	DM-LS
GCA+blood	Eotaxin	GCA+blood+TCA+blood+TUDCA+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.16	0.393	no	no	no	no	no	no	DM-LS
ACA+stool	Eotaxin	ACA+stool+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.417	0.393	no	no	no	no	no	no	DM-LS
ACA+stool	Eotaxin	ACA+stool+20:2+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.417	0.393	no	no	no	no	no	no	DM-LS
CDCA+blood	Eotaxin	CDCA+blood-MUFA%+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.506	0.393	no	no	no	no	no	no	DM-LS
CDCA+blood	Eotaxin	CDCA+blood-Cysteine+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.506	0.393	no	no	no	no	no	no	DM-LS
capric acid C6+blood	Eotaxin	capric acid C6+blood+UFA%+blood-Eotaxin	Indirect	serum_scfa	serum_cytokines	0.433	0.393	no	no	no	no	no	no	DM-LS
capric acid C6+blood	Eotaxin	capric acid C6+blood+TUDCA+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.433	0.393	no	no	no	no	no	no	DM-LS
capric acid C6+blood	Eotaxin	capric acid C6+blood+MUFA%+blood-Eotaxin	Indirect	serum_scfa	serum_cytokines	0.433	0.393	no	no	no	no	no	no	DM-LS
Pyramidobacter	Eotaxin	Pyramidobacter-Carbon metabolism-Eotaxin	Indirect	Genus	serum_cytokines	0.45	0.393	no	no	no	no	no	no	DM-LS
Pyramidobacter	Eotaxin	Pyramidobacter+Glucagon signaling pathway+Eotaxin	Indirect	Genus	serum_cytokines	0.45	0.393	no	no	no	no	no	no	DM-LS
Prevotella	Eotaxin	Prevotella+Aldosterone synthesis and secretion+Eotaxin	Indirect	Genus	serum_cytokines	0.287	0.393	no	no	no	no	no	no	DM-LS
Prevotella	Eotaxin	Prevotella+Adrenergic signaling in cardiomyocytes+Eotaxin	Indirect	Genus	serum_cytokines	0.287	0.393	no	no	no	no	no	no	DM-LS
Prevotella	Eotaxin	Prevotella+Chemical carcinogenesis - receptor activation+Eotaxin	Indirect	Genus	serum_cytokines	0.287	0.393	no	no	no	no	no	no	DM-LS
Prevotella	Eotaxin	Prevotella+Inflammatory mediator regulation of TRP channels+Eotaxin	Indirect	Genus	serum_cytokines	0.287	0.393	no	no	no	no	no	no	DM-LS
Prevotella	Eotaxin	Prevotella-Carbon metabolism-Eotaxin	Indirect	Genus	serum_cytokines	0.287	0.393	no	no	no	no	no	no	DM-LS
Prevotella	Eotaxin	Prevotella+Amphetamine addiction+Eotaxin	Indirect	Genus	serum_cytokines	0.287	0.393	no	no	no	no	no	no	DM-LS
Prevotella	Eotaxin	Prevotella+Dopaminergic synapse+Eotaxin	Indirect	Genus	serum_cytokines	0.287	0.393	no	no	no	no	no	no	DM-LS
Prevotella	Eotaxin	Prevotella+Cushing syndrome+Eotaxin	Indirect	Genus	serum_cytokines	0.287	0.393	no	no	no	no	no	no	DM-LS
Prevotella	Eotaxin	Prevotella+Melanogenesis+Eotaxin	Indirect	Genus	serum_cytokines	0.287	0.393	no	no	no	no	no	no	DM-LS
TCA+blood	Eotaxin	TCA+blood+TUDCA+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.339	0.393	no	no	no	no	no	no	DM-LS
iso-DCA+blood	Eotaxin	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.38	0.393	no	no	no	no	no	no	DM-LS
iso-DCA+blood	Eotaxin	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.38	0.393	no	no	no	no	no	no	DM-LS
iso-DCA+blood	Eotaxin	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.38	0.393	no	no	no	no	no	no	DM-LS
HCA+stool	Eotaxin	HCA+stool-Cysteine+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.155	0.393	no	no	no	no	no	no	DM-LS
Roseburia	Eotaxin	Roseburia-20:2+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.495	0.393	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Eotaxin	12-ketoDCA+stool+DCA+stool-ACA+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.505	0.393	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Eotaxin	12-ketoDCA+stool+LCA+stool-ACA+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.505	0.393	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Eotaxin	12-ketoDCA+stool+18:0/18:1-PE+blood-ACA+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.505	0.393	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Eotaxin	12-ketoDCA+stool+DCA+stool-UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.505	0.393	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Eotaxin	12-ketoDCA+stool-Glycine+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.505	0.393	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Eotaxin	12-ketoDCA+stool+18:0/18:1-PE+blood-UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.505	0.393	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Eotaxin	12-ketoDCA+stool-Glycine+blood+MUFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.505	0.393	no	no	no	no	no	no	DM-LS
GLCA+blood	Eotaxin	GLCA+blood-PUFA/MUFA+blood+UFA%+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.319	0.393	no	no	no	no	no	no	DM-LS
GLCA+blood	Eotaxin	GLCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.319	0.393	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	Eotaxin	L-Tryptophan+stool+n3+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.557	0.393	no	no	no	no	no	no	DM-LS
CA+blood	Eotaxin	CA+blood+Eotaxin	Direct	serum_bileacids	serum_cytokines	0.606	0.393	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	Eotaxin	L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.398	0.393	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	Eotaxin	L-Phenylalanine+stool+n3+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.398	0.393	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	Eotaxin	L-Phenylalanine+stool+Cysteine+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.398	0.393	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	Eotaxin	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin	Indirect	serum_scfa	serum_cytokines	0.407	0.393	no	no	no	no	no	no	DM-LS
GCA+stool	Eotaxin	GCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-LS
GCA+stool	Eotaxin	GCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-LS
GCA+stool	Eotaxin	GCA+stool+nutriCA+stool+CA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-LS
GCA+stool	Eotaxin	GCA+stool+GCDCA+stool+CA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-LS
GCA+stool	Eotaxin	GCA+stool+nutriCA+stool-n3+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-LS
GCA+stool	Eotaxin	GCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-LS
GCA+stool	Eotaxin	GCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-LS
GCA+stool	Eotaxin	GCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-LS
GCA+stool	Eotaxin	GCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-LS
GCA+stool	Eotaxin	GCA+stool+GCDCA+stool-Creatinine+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-LS
GCA+stool	Eotaxin	GCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-LS
GCA+stool	Eotaxin	GCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	Eotaxin	T-a-MCA+blood+UFA%+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.478	0.393	no	no	no	no	no	no	DM-LS
Coprococcus	Eotaxin	Coprococcus-Eotaxin	Direct	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	DM-LS
Oscillospira	Eotaxin	Oscillospira-Adrenergic signaling in cardiomyocytes+Eotaxin	Indirect	Genus	serum_cytokines	0.62	0.393	no	no	no	no	no	no	DM-LS
Oscillospira	Eotaxin	Oscillospira+Peroxisome-Eotaxin	Indirect	Genus	serum_cytokines	0.62	0.393	no	no	no	no	no	no	DM-LS
HCA+blood	Eotaxin	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.544	0.393	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Eotaxin	iso-LCA+stool-CDCA+blood-Cysteine+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Eotaxin	iso-LCA+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Eotaxin	iso-LCA+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Eotaxin	iso-LCA+stool-18:3n6+blood-20:5/18:0-PC+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Eotaxin	iso-LCA+stool-nutriCA+stool+CA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Eotaxin	iso-LCA+stool-18:3n6+blood-UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Eotaxin	iso-LCA+stool-Glycine+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Eotaxin	iso-LCA+stool-nutriCA+stool-n3+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Eotaxin	iso-LCA+stool-18:1-LPE+blood-n3+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Eotaxin	iso-LCA+stool-Sarcosine+blood-TUDCA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Eotaxin	iso-LCA+stool-18:1-LPE+blood-22:6n3+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Eotaxin	iso-LCA+stool-CDCA+blood-MUFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Eotaxin	iso-LCA+stool-Glycine+blood+MUFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Eotaxin	iso-LCA+stool+LCA+stool-ACA+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	Eotaxin	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.262	0.393	no	no	no	no	no	no	DM-LS
DCA+blood	Eotaxin	DCA+blood-MUFA%+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.122	0.393	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Eotaxin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood+UFA%+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.33	0.393	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Eotaxin	3-(3-Hydroxyphenyl)propanoic acid+stool-T-a-MCA+blood+UFA%+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.33	0.393	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Eotaxin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+UFA%+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.33	0.393	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Eotaxin	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood-UFA%+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.33	0.393	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Eotaxin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2/16:0-PC+blood+UFA%+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.33	0.393	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Eotaxin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+Cysteine+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.33	0.393	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Eotaxin	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood-MUFA%+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.33	0.393	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Eotaxin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.33	0.393	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Eotaxin	3-(3-Hydroxyphenyl)propanoic acid+stool+UDCA+stool-20:5/18:0-PC+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.33	0.393	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Eotaxin	3-(3-Hydroxyphenyl)propanoic acid+stool-16:0/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.33	0.393	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Eotaxin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.33	0.393	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Eotaxin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.33	0.393	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Eotaxin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2n6c+blood+20:2+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.33	0.393	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	DM-LS
TCA+stool	Eotaxin	TCA+stool-16:0/20:5-PC+blood+n3+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-LS
TCA+stool	Eotaxin	TCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-LS
TCA+stool	Eotaxin	TCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-LS
TCA+stool	Eotaxin	TCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-LS
TCA+stool	Eotaxin	TCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-LS
TCA+stool	Eotaxin	TCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-LS
TCA+stool	Eotaxin	TCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-LS
TCA+stool	Eotaxin	TCA+stool-16:0/20:5-PC+blood-MUFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-LS
TCA+stool	Eotaxin	TCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-LS
TCA+stool	Eotaxin	TCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-LS
TCA+stool	Eotaxin	TCA+stool+18:1/18:1-PC+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-LS
TCA+stool	Eotaxin	TCA+stool+16:0/20:3-PC+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-LS
TCA+stool	Eotaxin	TCA+stool-16:0/20:5-PC+blood-20:2+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-LS
TCA+stool	Eotaxin	TCA+stool+18:1/18:1-PC+blood+20:2+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-LS
TCA+stool	Eotaxin	TCA+stool+16:0/20:3-PC+blood+20:2+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-LS
TCA+stool	Eotaxin	TCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-LS
TCA+stool	Eotaxin	TCA+stool-16:0/20:5-PC+blood+CA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	DM-LS
HDCA+stool	Eotaxin	HDCA+stool-18:1/20:3-PC+blood-CA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	DM-LS
HDCA+stool	Eotaxin	HDCA+stool-nutriCA+stool+CA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	DM-LS
HDCA+stool	Eotaxin	HDCA+stool+LCA+stool-ACA+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	DM-LS
HDCA+stool	Eotaxin	HDCA+stool-18:1-LPE+blood-22:6n3+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	DM-LS
HDCA+stool	Eotaxin	HDCA+stool-18:1/20:3-PC+blood+20:2+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	DM-LS
HDCA+stool	Eotaxin	HDCA+stool-18:1-LPC+blood+20:2+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	DM-LS
HDCA+stool	Eotaxin	HDCA+stool-16:0/20:3-PC+blood+20:2+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	DM-LS
HDCA+stool	Eotaxin	HDCA+stool-18:1/18:1-PC+blood+20:2+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	DM-LS
HDCA+stool	Eotaxin	HDCA+stool+EPA+blood+n3+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	DM-LS
HDCA+stool	Eotaxin	HDCA+stool-nutriCA+stool-n3+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	DM-LS
HDCA+stool	Eotaxin	HDCA+stool-18:1-LPE+blood-n3+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	DM-LS
HDCA+stool	Eotaxin	HDCA+stool-16:0/20:3-PC+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	DM-LS
HDCA+stool	Eotaxin	HDCA+stool-18:1/18:1-PC+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	DM-LS
Lachnospira	Eotaxin	Lachnospira+Choline+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.279	0.393	no	no	no	no	no	no	DM-LS
Fusobacterium	Eotaxin	Fusobacterium+UFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.628	0.393	no	no	no	no	no	no	DM-LS
Fusobacterium	Eotaxin	Fusobacterium+MUFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.628	0.393	no	no	no	no	no	no	DM-LS
isobutyric acid C4+blood	Eotaxin	isobutyric acid C4+blood+MUFA%+blood-Eotaxin	Indirect	serum_scfa	serum_cytokines	0.0151	0.393	up	up	no	no	no	no	DM-LS
GCDCA+stool	Eotaxin	GCDCA+stool-Creatinine+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0471	0.393	no	dn	no	no	no	no	DM-LS
GCDCA+stool	Eotaxin	GCDCA+stool+CA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0471	0.393	no	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool-Acetic acid+stool-Cysteine+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool-Propionic acid+stool-ACA+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+n3+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool-Propionic acid+stool-MUFA%+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool-Propionic acid+stool-UFA%+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool-Acetic acid+stool-UFA%+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	DM-LS
Odoribacter	Eotaxin	Odoribacter+Choline+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.798	0.393	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool-nutriCA+stool+CA+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool-nutriCA+stool-n3+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	DM-LS
Lachnobacterium	Eotaxin	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.867	0.393	no	no	no	no	no	no	DM-LS
Kynurenic acid+stool	Eotaxin	Kynurenic acid+stool-nutriCA+stool+CA+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.037	0.393	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Eotaxin	Kynurenic acid+stool-nutriCA+stool-n3+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.037	0.393	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Eotaxin	Kynurenic acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.037	0.393	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Eotaxin	Kynurenic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.037	0.393	dn	dn	no	no	no	no	DM-LS
Anaerostipes	Eotaxin	Anaerostipes-Non-small cell lung cancer+Eotaxin	Indirect	Genus	serum_cytokines	0.568	0.393	no	no	no	no	no	no	DM-LS
Anaerostipes	Eotaxin	Anaerostipes+TUDCA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.568	0.393	no	no	no	no	no	no	DM-LS
TUDCA+stool	Eotaxin	TUDCA+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.241	0.393	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool-nutriCA+stool-n3+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool-nutriCA+stool+CA+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Arachidonic acid metabolism+Biosynthesis of amino acids-Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Betaine+blood+UFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Glutathione metabolism-Choline metabolism in cancer+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Arachidonic acid metabolism-Choline metabolism in cancer+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Glutathione metabolism-Cholinergic synapse+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Glutathione metabolism-mRNA surveillance pathway+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Arachidonic acid metabolism-mRNA surveillance pathway+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Glutathione metabolism-Non-small cell lung cancer+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Arachidonic acid metabolism-Non-small cell lung cancer+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+18:0/20:2-PC+blood+20:2+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Glutathione metabolism-Colorectal cancer+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Arachidonic acid metabolism-Colorectal cancer+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Arachidonic acid metabolism-Cell cycle+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Arachidonic acid metabolism+Choline+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Glutathione metabolism-ErbB signaling pathway+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Arachidonic acid metabolism-ErbB signaling pathway+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Glutathione metabolism-Phosphatidylinositol signaling system+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Arachidonic acid metabolism-Phosphatidylinositol signaling system+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella-18:0/22:6-PA+blood+22:6n3+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Glutathione metabolism-Gastric cancer+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Arachidonic acid metabolism-Gastric cancer+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Glutathione metabolism-Glioma+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Arachidonic acid metabolism-Glioma+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Glutathione metabolism-Signaling pathways regulating pluripotency of stem cells+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Arachidonic acid metabolism-Signaling pathways regulating pluripotency of stem cells+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Glutathione metabolism-Spliceosome+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Arachidonic acid metabolism-Spliceosome+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Betaine+blood-CA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Glutathione metabolism-Long-term potentiation+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
Paraprevotella	Eotaxin	Paraprevotella+Arachidonic acid metabolism-Long-term potentiation+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	DM-LS
iso-LCA+blood	Eotaxin	iso-LCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.507	0.393	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	Eotaxin	Phenylacetic acid+stool+Cysteine+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.785	0.393	no	no	no	no	no	no	DM-LS
Gemmiger	Eotaxin	Gemmiger-18:1-LPC+blood+20:2+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-LS
Gemmiger	Eotaxin	Gemmiger+L-Phenylalanine+blood+n3+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	DM-LS
GDCA+stool	Eotaxin	GDCA+stool-L-Phenylalanine+blood+n3+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-LS
GDCA+stool	Eotaxin	GDCA+stool-L-Isoleucine+blood+n3+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-LS
GDCA+stool	Eotaxin	GDCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-LS
GDCA+stool	Eotaxin	GDCA+stool-L-Histidine+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-LS
GDCA+stool	Eotaxin	GDCA+stool+20:3/18:0-PC+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-LS
GDCA+stool	Eotaxin	GDCA+stool-L-Isoleucine+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-LS
GDCA+stool	Eotaxin	GDCA+stool+Glycine+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-LS
GDCA+stool	Eotaxin	GDCA+stool+24:1+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-LS
GDCA+stool	Eotaxin	GDCA+stool-Propionic acid+stool-UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-LS
GDCA+stool	Eotaxin	GDCA+stool-L-Histidine+blood+MUFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-LS
GDCA+stool	Eotaxin	GDCA+stool+Glycine+blood+MUFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-LS
GDCA+stool	Eotaxin	GDCA+stool-Propionic acid+stool-MUFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-LS
GDCA+stool	Eotaxin	GDCA+stool+20:3/18:0-PC+blood+ACA+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-LS
GDCA+stool	Eotaxin	GDCA+stool+24:1+blood+ACA+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-LS
GDCA+stool	Eotaxin	GDCA+stool-Propionic acid+stool-ACA+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-LS
GDCA+stool	Eotaxin	GDCA+stool+20:3/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	DM-LS
Methanobrevibacter	Eotaxin	Methanobrevibacter+n3+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.629	0.393	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	Eotaxin	L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.44	0.393	no	no	no	no	no	no	DM-LS
CDCA+stool	Eotaxin	CDCA+stool-20:5/18:0-PC+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	DM-LS
CA+stool	Eotaxin	CA+stool+CA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	DM-LS
Slackia	Eotaxin	Slackia+Platinum drug resistance+Eotaxin	Indirect	Genus	serum_cytokines	0.94	0.393	no	no	no	no	no	no	DM-LS
Slackia	Eotaxin	Slackia-Neutrophil extracellular trap formation-Eotaxin	Indirect	Genus	serum_cytokines	0.94	0.393	no	no	no	no	no	no	DM-LS
Slackia	Eotaxin	Slackia-Cysteine+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.94	0.393	no	no	no	no	no	no	DM-LS
HDCA+blood	Eotaxin	HDCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.483	0.393	no	no	no	no	no	no	DM-LS
UDCA+stool	Eotaxin	UDCA+stool-20:5/18:0-PC+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.266	0.393	no	no	no	no	no	no	DM-LS
TDCA+stool	Eotaxin	TDCA+stool+UDCA+stool-20:5/18:0-PC+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.963	0.393	no	no	no	no	no	no	DM-LS
nutriCA+stool	Eotaxin	nutriCA+stool+CA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.481	0.393	no	no	no	no	no	no	DM-LS
nutriCA+stool	Eotaxin	nutriCA+stool-n3+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.481	0.393	no	no	no	no	no	no	DM-LS
GDCA+blood	Eotaxin	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.632	0.393	no	no	no	no	no	no	DM-LS
acetic acid C2+blood	Eotaxin	acetic acid C2+blood+total_blood_scfa+blood+TUDCA+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.000193	0.393	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	Eotaxin	acetic acid C2+blood-Sarcosine+blood-TUDCA+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.000193	0.393	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	Eotaxin	acetic acid C2+blood+capric acid C6+blood+TUDCA+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.000193	0.393	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	Eotaxin	acetic acid C2+blood+capric acid C6+blood+MUFA%+blood-Eotaxin	Indirect	serum_scfa	serum_cytokines	0.000193	0.393	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	Eotaxin	acetic acid C2+blood-d18:1-14:1-SM+blood-MUFA%+blood-Eotaxin	Indirect	serum_scfa	serum_cytokines	0.000193	0.393	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	Eotaxin	acetic acid C2+blood+capric acid C6+blood+UFA%+blood-Eotaxin	Indirect	serum_scfa	serum_cytokines	0.000193	0.393	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	Eotaxin	acetic acid C2+blood-d18:1-14:1-SM+blood-UFA%+blood-Eotaxin	Indirect	serum_scfa	serum_cytokines	0.000193	0.393	up	dn	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	Eotaxin	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.117	0.393	no	no	no	no	no	no	DM-LS
Adlercreutzia	Eotaxin	Adlercreutzia-16:0/20:5-PC+blood-20:2+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.548	0.393	no	no	no	no	no	no	DM-LS
Adlercreutzia	Eotaxin	Adlercreutzia+18:1-LPC+blood+20:2+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.548	0.393	no	no	no	no	no	no	DM-LS
Adlercreutzia	Eotaxin	Adlercreutzia-EPA+blood+n3+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.548	0.393	no	no	no	no	no	no	DM-LS
Adlercreutzia	Eotaxin	Adlercreutzia-16:0/20:5-PC+blood+n3+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.548	0.393	no	no	no	no	no	no	DM-LS
Adlercreutzia	Eotaxin	Adlercreutzia-16:0/20:5-PC+blood+CA+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.548	0.393	no	no	no	no	no	no	DM-LS
Adlercreutzia	Eotaxin	Adlercreutzia-16:0/20:5-PC+blood-MUFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.548	0.393	no	no	no	no	no	no	DM-LS
Adlercreutzia	Eotaxin	Adlercreutzia+16:0/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.548	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium+cGMP-PKG signaling pathway+Lipid and atherosclerosis-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium+cGMP-PKG signaling pathway+Endocytosis-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium+cGMP-PKG signaling pathway+IL-17 signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium+PUFA/MUFA+blood+UFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium-14:0/20:4-PC+blood-UFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium-Acetic acid+stool-UFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
 Clostridium	Eotaxin	Clostridium+Acetic acid+stool-UFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	NA	0.393	NA	NA	NA	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium-Acetic acid+stool-UFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
 Clostridium	Eotaxin	Clostridium+Acetic acid+stool-UFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	NA	0.393	NA	NA	NA	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium+cGMP-PKG signaling pathway+Fc gamma R-mediated phagocytosis-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium+cGMP-PKG signaling pathway+Neutrophil extracellular trap formation-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium+cGMP-PKG signaling pathway+Pathogenic Escherichia coli infection-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium-18:0/20:2-PC+blood+20:2+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium+CDCA+blood-Cysteine+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium-14:0/20:4-PC+blood-Cysteine+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium-Acetic acid+stool-Cysteine+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
 Clostridium	Eotaxin	Clostridium+Acetic acid+stool-Cysteine+blood-Eotaxin	Indirect	Genus	serum_cytokines	NA	0.393	NA	NA	NA	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium-Acetic acid+stool-Cysteine+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
 Clostridium	Eotaxin	Clostridium+Acetic acid+stool-Cysteine+blood-Eotaxin	Indirect	Genus	serum_cytokines	NA	0.393	NA	NA	NA	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium-14:0/20:4-PC+blood-Creatinine+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium-14:0/18:2-PC+blood-Creatinine+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium-14:0/20:4-PC+blood-20:5/18:0-PC+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium+CDCA+blood-MUFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium-14:0/20:4-PC+blood-MUFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium+cGMP-PKG signaling pathway+MUFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
Clostridium	Eotaxin	Clostridium-14:0/18:2-PC+blood-MUFA%+blood-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+n3+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood-MUFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+UFA%+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood-20:2+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+20:2+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+20:2+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-TCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Eotaxin	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+CA+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.48	0.393	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	Eotaxin	12-ketoDCA+blood-8-HETE+blood-ACA+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.517	0.393	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	Eotaxin	12-ketoDCA+blood-20:3-LPE+blood-22:6n3+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.517	0.393	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	Eotaxin	12-ketoDCA+blood-20:3-LPE+blood+Choline+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.517	0.393	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	Eotaxin	12-ketoDCA+blood-L-Lysine+blood+UFA%+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.517	0.393	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	Eotaxin	12-ketoDCA+blood-L-Arginine+blood+UFA%+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.517	0.393	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	Eotaxin	12-ketoDCA+blood-20:3-LPE+blood-n3+blood-Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.517	0.393	no	no	no	no	no	no	DM-LS
Butyricicoccus	Eotaxin	Butyricicoccus+Allograft rejection-Eotaxin	Indirect	Genus	serum_cytokines	0.852	0.393	no	no	no	no	no	no	DM-LS
Butyricicoccus	Eotaxin	Butyricicoccus+Viral myocarditis-Eotaxin	Indirect	Genus	serum_cytokines	0.852	0.393	no	no	no	no	no	no	DM-LS
Butyricicoccus	Eotaxin	Butyricicoccus+Cell adhesion molecules-Eotaxin	Indirect	Genus	serum_cytokines	0.852	0.393	no	no	no	no	no	no	DM-LS
Butyricicoccus	Eotaxin	Butyricicoccus+Type I diabetes mellitus-Eotaxin	Indirect	Genus	serum_cytokines	0.852	0.393	no	no	no	no	no	no	DM-LS
Butyricicoccus	Eotaxin	Butyricicoccus+Graft-versus-host disease-Eotaxin	Indirect	Genus	serum_cytokines	0.852	0.393	no	no	no	no	no	no	DM-LS
Butyricicoccus	Eotaxin	Butyricicoccus+Phagosome-Eotaxin	Indirect	Genus	serum_cytokines	0.852	0.393	no	no	no	no	no	no	DM-LS
Butyricicoccus	Eotaxin	Butyricicoccus+Autoimmune thyroid disease-Eotaxin	Indirect	Genus	serum_cytokines	0.852	0.393	no	no	no	no	no	no	DM-LS
Blautia	PDGF-bb	Blautia-16:0/22:6-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-LS
Blautia	PDGF-bb	Blautia+d18:1-16:1-SM+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-LS
Blautia	PDGF-bb	Blautia-16:0/18:2-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-LS
Blautia	PDGF-bb	Blautia+d18:0-24:1-SM+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-LS
Blautia	PDGF-bb	Blautia+14:0/20:4-PC+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-LS
Blautia	PDGF-bb	Blautia-18:1/16:0-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-LS
Blautia	PDGF-bb	Blautia+d18:1-16:1-SM+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-LS
Blautia	PDGF-bb	Blautia-16:0/18:2-PC+blood-d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-LS
Blautia	PDGF-bb	Blautia+d18:0-24:1-SM+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-LS
Blautia	PDGF-bb	Blautia+14:0/20:4-PC+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-LS
Blautia	PDGF-bb	Blautia-18:1/16:0-PC+blood-d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-LS
Blautia	PDGF-bb	Blautia-16:0/18:2-PC+blood+Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-LS
Blautia	PDGF-bb	Blautia+14:0/20:4-PC+blood-Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-LS
Blautia	PDGF-bb	Blautia-18:1/16:0-PC+blood+Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-LS
Blautia	PDGF-bb	Blautia-12-ketoDCA+stool-L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-LS
Blautia	PDGF-bb	Blautia+d18:0-24:1-SM+blood+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	DM-LS
Parabacteroides	PDGF-bb	Parabacteroides-EGFR tyrosine kinase inhibitor resistance-Phospholipase D signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	DM-LS
Parabacteroides	PDGF-bb	Parabacteroides-RNA transport-Phospholipase D signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	DM-LS
Parabacteroides	PDGF-bb	Parabacteroides-HIF-1 signaling pathway-Phospholipase D signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	DM-LS
Parabacteroides	PDGF-bb	Parabacteroides+20:0+blood+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	DM-LS
Parabacteroides	PDGF-bb	Parabacteroides-Glucagon signaling pathway-18:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	DM-LS
Parabacteroides	PDGF-bb	Parabacteroides-Spliceosome+Calcium signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	DM-LS
Parabacteroides	PDGF-bb	Parabacteroides-Glucagon signaling pathway+Cocaine addiction+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	DM-LS
Parabacteroides	PDGF-bb	Parabacteroides-Glucagon signaling pathway-Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	DM-LS
Parabacteroides	PDGF-bb	Parabacteroides-TCA+stool-L-Tryptophan+urine+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	DM-LS
Parabacteroides	PDGF-bb	Parabacteroides-Glucagon signaling pathway+L-Tryptophan+urine+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	DM-LS
Parabacteroides	PDGF-bb	Parabacteroides-EGFR tyrosine kinase inhibitor resistance+L-Tryptophan+urine+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	DM-LS
Parabacteroides	PDGF-bb	Parabacteroides-PI3K-Akt signaling pathway+L-Tryptophan+urine+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	DM-LS
Parabacteroides	PDGF-bb	Parabacteroides-RNA transport+L-Tryptophan+urine+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	DM-LS
Dorea	PDGF-bb	Dorea+PDGF-bb	Direct	Genus	serum_cytokines	0.00362	0.111	up	no	dn	no	no	no	DM-LS
Faecalibacterium	PDGF-bb	Faecalibacterium-Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.0039	0.111	no	dn	dn	no	no	no	DM-LS
TUDCA+blood	PDGF-bb	TUDCA+blood+Eotaxin-GM-CSF+IL-1b-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.0282	0.111	no	no	dn	no	no	no	DM-LS
TUDCA+blood	PDGF-bb	TUDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.0282	0.111	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	PDGF-bb	isocapric acid iso-C6+blood-n3+blood-L-Tryptophan+urine+PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.0458	0.111	no	no	dn	no	no	no	DM-LS
Bacteroides	PDGF-bb	Bacteroides+n3+blood-L-Tryptophan+urine+PDGF-bb	Indirect	Genus	serum_cytokines	0.000267	0.111	dn	dn	up	no	no	no	DM-LS
Bacteroides	PDGF-bb	Bacteroides+22:6n3+blood-L-Tryptophan+urine+PDGF-bb	Indirect	Genus	serum_cytokines	0.000267	0.111	dn	dn	up	no	no	no	DM-LS
Bacteroides	PDGF-bb	Bacteroides+Cytokine-cytokine receptor interaction+Hematopoietic cell lineage-PDGF-bb	Indirect	Genus	serum_cytokines	0.000267	0.111	dn	dn	up	no	no	no	DM-LS
Propionic acid+stool	PDGF-bb	Propionic acid+stool-18:0/18:2-PC+blood+Cysteine+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0436	0.111	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	PDGF-bb	Propionic acid+stool-TCA+stool-L-Tryptophan+urine+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0436	0.111	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	PDGF-bb	Propionic acid+stool-20:3/18:0-PC+blood-L-Tryptophan+urine+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0436	0.111	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	PDGF-bb	Propionic acid+stool-18:0/18:0-PC+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0436	0.111	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	PDGF-bb	Propionic acid+stool-18:0/18:1-PC+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0436	0.111	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	PDGF-bb	Propionic acid+stool-18:0/18:1-PC+blood+L-Alanine+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0436	0.111	dn	no	up	no	no	no	DM-LS
5-Hydroxyindole-3-acetic Acid+urine	PDGF-bb	5-Hydroxyindole-3-acetic Acid+urine-DL-Indole-3-lactic acid+urine+L-Phenylalanine+urine+L-Tryptophan+urine+PDGF-bb	Indirect	urine_cometabolism	serum_cytokines	0.0405	0.111	no	dn	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Transcriptional misregulation in cancer+16:0-LPC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Transcriptional misregulation in cancer+18:0-LPE+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Transcriptional misregulation in cancer+18:0-LPC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-16:0/18:2-PC+blood+Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-18:1/16:0-PC+blood+Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+d18:1-14:0-SM+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+d18:0-16:0-SM+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+d18:1-16:1-SM+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-16:0/18:2-PC+blood-d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-18:1/16:0-PC+blood-d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+d18:1-14:0-SM+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+d18:0-16:0-SM+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+d18:1-16:1-SM+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-16:0/18:2-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-18:1/16:0-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]-TCA+stool-L-Tryptophan+urine+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+16:0/20:4-PI+blood+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+d18:0-16:0-SM+blood+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+16:0/18:2-PI+blood+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	PDGF-bb	[Ruminococcus]+18:0/18:2-PI+blood+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	DM-LS
GUDCA+blood	PDGF-bb	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.0766	0.111	no	no	dn	no	no	no	DM-LS
GUDCA+blood	PDGF-bb	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-1b-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.0766	0.111	no	no	dn	no	no	no	DM-LS
Acetic acid+stool	PDGF-bb	Acetic acid+stool+Butyric acid+stool+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0656	0.111	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	PDGF-bb	Acetic acid+stool-Cysteine+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0656	0.111	dn	no	no	no	no	no	DM-LS
Alistipes	PDGF-bb	Alistipes-HIF-1 signaling pathway-Phospholipase D signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.0114	0.111	no	up	no	no	no	no	DM-LS
Alistipes	PDGF-bb	Alistipes+12-ketoDCA+stool-L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0114	0.111	no	up	no	no	no	no	DM-LS
Butyricimonas	PDGF-bb	Butyricimonas-Prion disease-Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.17	0.111	no	no	no	no	no	no	DM-LS
Butyricimonas	PDGF-bb	Butyricimonas-Cardiac muscle contraction-Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.17	0.111	no	no	no	no	no	no	DM-LS
Butyricimonas	PDGF-bb	Butyricimonas-14:0/20:4-PC+blood-Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.17	0.111	no	no	no	no	no	no	DM-LS
Butyricimonas	PDGF-bb	Butyricimonas-14:0/20:4-PC+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.17	0.111	no	no	no	no	no	no	DM-LS
Butyricimonas	PDGF-bb	Butyricimonas-d18:0-24:1-SM+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.17	0.111	no	no	no	no	no	no	DM-LS
Butyricimonas	PDGF-bb	Butyricimonas-d18:1-14:0-SM+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.17	0.111	no	no	no	no	no	no	DM-LS
Butyricimonas	PDGF-bb	Butyricimonas-14:0/20:4-PC+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.17	0.111	no	no	no	no	no	no	DM-LS
Butyricimonas	PDGF-bb	Butyricimonas-d18:0-24:1-SM+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.17	0.111	no	no	no	no	no	no	DM-LS
Butyricimonas	PDGF-bb	Butyricimonas-d18:1-14:0-SM+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.17	0.111	no	no	no	no	no	no	DM-LS
Butyricimonas	PDGF-bb	Butyricimonas-d18:0-24:1-SM+blood+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.17	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella-T cell receptor signaling pathway+L-Tryptophan+urine+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella-Insulin resistance+18:0-LPC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella-NF-kappa B signaling pathway+18:0-LPC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella-NF-kappa B signaling pathway-Hematopoietic cell lineage-PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella-NF-kappa B signaling pathway+Phospholipase D signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella-MAPK signaling pathway-16:0-LPC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella-HDCA+stool-16:0-LPC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella+Parkinson disease+16:0-LPC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella-Gastric cancer-MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella-Hepatitis B+18:0-LPE+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella+Parkinson disease+Cocaine addiction+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella-Hepatitis B+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella-Insulin resistance+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella-Prostate cancer+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella-Neurotrophin signaling pathway+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella-RNA degradation+Calcium signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella-MAPK signaling pathway-d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
Collinsella	PDGF-bb	Collinsella-Prolactin signaling pathway-d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	PDGF-bb	total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-1b-PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.168	0.111	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	PDGF-bb	total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.168	0.111	no	no	no	no	no	no	DM-LS
[Eubacterium]	PDGF-bb	[Eubacterium]-Fluid shear stress and atherosclerosis-L-Tryptophan+urine+PDGF-bb	Indirect	Genus	serum_cytokines	0.0692	0.111	no	no	no	no	no	no	DM-LS
[Eubacterium]	PDGF-bb	[Eubacterium]-Salmonella infection-16:0-LPC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0692	0.111	no	no	no	no	no	no	DM-LS
[Eubacterium]	PDGF-bb	[Eubacterium]-Phagosome+18:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.0692	0.111	no	no	no	no	no	no	DM-LS
[Eubacterium]	PDGF-bb	[Eubacterium]-Phagosome+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.0692	0.111	no	no	no	no	no	no	DM-LS
LCA+stool	PDGF-bb	LCA+stool+18:1/18:1-PE+blood+MUFA+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.314	0.111	no	no	no	no	no	no	DM-LS
LCA+stool	PDGF-bb	LCA+stool-TCA+stool-L-Tryptophan+urine+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.314	0.111	no	no	no	no	no	no	DM-LS
LCA+stool	PDGF-bb	LCA+stool-20:3/18:0-PC+blood-L-Tryptophan+urine+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.314	0.111	no	no	no	no	no	no	DM-LS
Akkermansia	PDGF-bb	Akkermansia-L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.23	0.111	no	no	no	no	no	no	DM-LS
Bifidobacterium	PDGF-bb	Bifidobacterium+Chemical carcinogenesis - receptor activation+Small cell lung cancer+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	DM-LS
Bifidobacterium	PDGF-bb	Bifidobacterium-18:2/20:4-PC+blood+20:0-LPC+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	DM-LS
Bifidobacterium	PDGF-bb	Bifidobacterium-18:2/20:4-PC+blood+20:3/16:0-PC+blood-d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	DM-LS
Bifidobacterium	PDGF-bb	Bifidobacterium-18:2/20:4-PC+blood+20:0-LPC+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	DM-LS
3-Hydroxytyramine hydrochloride+urine	PDGF-bb	3-Hydroxytyramine hydrochloride+urine+L-Phenylalanine+urine+L-Tryptophan+urine+PDGF-bb	Indirect	urine_cometabolism	serum_cytokines	0.288	0.111	no	no	no	no	no	no	DM-LS
Ruminococcus	PDGF-bb	Ruminococcus+22:6n3+blood-L-Tryptophan+urine+PDGF-bb	Indirect	Genus	serum_cytokines	0.335	0.111	no	no	no	no	no	no	DM-LS
Ruminococcus	PDGF-bb	Ruminococcus+Phagosome+18:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.335	0.111	no	no	no	no	no	no	DM-LS
Ruminococcus	PDGF-bb	Ruminococcus+Endocytosis+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.335	0.111	no	no	no	no	no	no	DM-LS
Ruminococcus	PDGF-bb	Ruminococcus+Phagosome+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.335	0.111	no	no	no	no	no	no	DM-LS
Ruminococcus	PDGF-bb	Ruminococcus+Cell adhesion molecules+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.335	0.111	no	no	no	no	no	no	DM-LS
GCDCA+blood	PDGF-bb	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.31	0.111	no	no	no	no	no	no	DM-LS
GCDCA+blood	PDGF-bb	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.31	0.111	no	no	no	no	no	no	DM-LS
Succinivibrio	PDGF-bb	Succinivibrio-Phospholipase D signaling pathway+PDGF-bb	Indirect	Genus	serum_cytokines	0.138	0.111	no	no	no	no	no	no	DM-LS
ACA+blood	PDGF-bb	ACA+blood-Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.338	0.111	no	no	no	no	no	no	DM-LS
ACA+blood	PDGF-bb	ACA+blood-Eotaxin-GM-CSF+IL-1b-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.338	0.111	no	no	no	no	no	no	DM-LS
DCA+stool	PDGF-bb	DCA+stool-18:0/18:2-PC+blood+Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.195	0.111	no	no	no	no	no	no	DM-LS
DCA+stool	PDGF-bb	DCA+stool-TCA+stool-L-Tryptophan+urine+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.195	0.111	no	no	no	no	no	no	DM-LS
DCA+stool	PDGF-bb	DCA+stool-20:3/18:0-PC+blood-L-Tryptophan+urine+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.195	0.111	no	no	no	no	no	no	DM-LS
DCA+stool	PDGF-bb	DCA+stool+18:1/18:1-PE+blood+MUFA+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.195	0.111	no	no	no	no	no	no	DM-LS
DCA+stool	PDGF-bb	DCA+stool+HDCA+stool-16:0-LPC+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.195	0.111	no	no	no	no	no	no	DM-LS
2-hydroxyhippuric acid+urine	PDGF-bb	2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PDGF-bb	Indirect	urine_cometabolism	serum_cytokines	0.215	0.111	no	no	no	no	no	no	DM-LS
Butyric acid+stool	PDGF-bb	Butyric acid+stool+PDGF-bb	Direct	stool_scfa	serum_cytokines	0.102	0.111	dn	no	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	PDGF-bb	4-hydroxybenzoic acid+stool-Phenylacetic acid+stool+Cysteine+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.111	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	PDGF-bb	4-hydroxybenzoic acid+stool-HDCA+stool-16:0-LPC+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.111	no	dn	no	no	no	no	DM-LS
GCA+blood	PDGF-bb	GCA+blood+GDCA+blood+iso-LCA+blood+L-Proline+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.16	0.111	no	no	no	no	no	no	DM-LS
GCA+blood	PDGF-bb	GCA+blood+GDCA+blood-isocapric acid iso-C6+blood-n3+blood-L-Tryptophan+urine+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.16	0.111	no	no	no	no	no	no	DM-LS
ACA+stool	PDGF-bb	ACA+stool+16:0-LPC+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.417	0.111	no	no	no	no	no	no	DM-LS
CDCA+blood	PDGF-bb	CDCA+blood-Cysteine+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.506	0.111	no	no	no	no	no	no	DM-LS
CDCA+blood	PDGF-bb	CDCA+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.506	0.111	no	no	no	no	no	no	DM-LS
capric acid C6+blood	PDGF-bb	capric acid C6+blood-L-Alanine+blood+PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.433	0.111	no	no	no	no	no	no	DM-LS
Pyramidobacter	PDGF-bb	Pyramidobacter+L-Tryptophan+urine+PDGF-bb	Indirect	Genus	serum_cytokines	0.45	0.111	no	no	no	no	no	no	DM-LS
Prevotella	PDGF-bb	Prevotella+PDGF-bb	Direct	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	DM-LS
TCA+blood	PDGF-bb	TCA+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-1b-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.339	0.111	no	no	no	no	no	no	DM-LS
TCA+blood	PDGF-bb	TCA+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.339	0.111	no	no	no	no	no	no	DM-LS
iso-DCA+blood	PDGF-bb	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-L-Tryptophan+urine+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.38	0.111	no	no	no	no	no	no	DM-LS
HCA+stool	PDGF-bb	HCA+stool-Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.155	0.111	no	no	no	no	no	no	DM-LS
HCA+stool	PDGF-bb	HCA+stool-18:1+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.155	0.111	no	no	no	no	no	no	DM-LS
Roseburia	PDGF-bb	Roseburia-16:0-LPC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	PDGF-bb	12-ketoDCA+stool-L-Alanine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.505	0.111	no	no	no	no	no	no	DM-LS
4-Hydroxyphenylacetic acid+urine	PDGF-bb	4-Hydroxyphenylacetic acid+urine-5-Hydroxyindole-3-acetic Acid+urine-DL-Indole-3-lactic acid+urine+L-Phenylalanine+urine+L-Tryptophan+urine+PDGF-bb	Indirect	urine_cometabolism	serum_cytokines	0.0321	0.111	up	up	no	no	no	no	DM-LS
GLCA+blood	PDGF-bb	GLCA+blood+iso-LCA+blood+L-Proline+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.319	0.111	no	no	no	no	no	no	DM-LS
GLCA+blood	PDGF-bb	GLCA+blood+L-Homocystine+blood-2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.319	0.111	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	PDGF-bb	L-Tryptophan+stool+16:0/22:6-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.557	0.111	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	PDGF-bb	L-Tryptophan+stool+16:1/16:0-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.557	0.111	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	PDGF-bb	L-Tryptophan+stool+L-Tyrosine+stool-16:1+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.557	0.111	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	PDGF-bb	L-Tryptophan+stool+L-Tyrosine+stool-18:0-LPE+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.557	0.111	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	PDGF-bb	L-Tryptophan+stool+Phenylacetic acid+stool+Cysteine+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.557	0.111	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	PDGF-bb	L-Tryptophan+stool+16:1/16:0-PC+blood+Cysteine+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.557	0.111	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	PDGF-bb	L-Tryptophan+stool+20:3/18:0-PC+blood-L-Tryptophan+urine+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.557	0.111	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	PDGF-bb	L-Tryptophan+stool+n3+blood-L-Tryptophan+urine+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.557	0.111	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	PDGF-bb	L-Tryptophan+stool+16:1/16:0-PC+blood-d18:1-20:0-SM+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.557	0.111	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	PDGF-bb	L-Tryptophan+stool-18:3n6+blood+L-Alanine+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.557	0.111	no	no	no	no	no	no	DM-LS
CA+blood	PDGF-bb	CA+blood-Cysteine+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.606	0.111	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	PDGF-bb	L-Phenylalanine+stool-18:0-LPE+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.398	0.111	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	PDGF-bb	L-Phenylalanine+stool+Cysteine+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.398	0.111	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	PDGF-bb	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b-PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.407	0.111	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	PDGF-bb	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.407	0.111	no	no	no	no	no	no	DM-LS
GCA+stool	PDGF-bb	GCA+stool+16:0/18:1-PC+blood+18:1+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0809	0.111	no	no	no	no	no	no	DM-LS
GCA+stool	PDGF-bb	GCA+stool+18:0/16:0-PC+blood+18:1+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0809	0.111	no	no	no	no	no	no	DM-LS
GCA+stool	PDGF-bb	GCA+stool+16:0/18:1-PC+blood+Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0809	0.111	no	no	no	no	no	no	DM-LS
GCA+stool	PDGF-bb	GCA+stool+18:0/16:0-PC+blood+Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0809	0.111	no	no	no	no	no	no	DM-LS
GCA+stool	PDGF-bb	GCA+stool+TCA+stool-L-Tryptophan+urine+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0809	0.111	no	no	no	no	no	no	DM-LS
GCA+stool	PDGF-bb	GCA+stool+16:0/18:1-PC+blood+16:1+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0809	0.111	no	no	no	no	no	no	DM-LS
GCA+stool	PDGF-bb	GCA+stool+16:0/18:1-PC+blood+MUFA+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0809	0.111	no	no	no	no	no	no	DM-LS
GCA+stool	PDGF-bb	GCA+stool+18:0/16:0-PC+blood+MUFA+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0809	0.111	no	no	no	no	no	no	DM-LS
GCA+stool	PDGF-bb	GCA+stool+16:0/18:3-PC+blood+L-Alanine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0809	0.111	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	PDGF-bb	T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.478	0.111	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	PDGF-bb	T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.478	0.111	no	no	no	no	no	no	DM-LS
Coprococcus	PDGF-bb	Coprococcus+Butyric acid+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.612	0.111	no	no	no	no	no	no	DM-LS
Oscillospira	PDGF-bb	Oscillospira-Adrenergic signaling in cardiomyocytes+Cocaine addiction+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-LS
Oscillospira	PDGF-bb	Oscillospira+Peroxisome-L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-LS
Oscillospira	PDGF-bb	Oscillospira-Alzheimer disease-Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	DM-LS
HCA+blood	PDGF-bb	HCA+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.544	0.111	no	no	no	no	no	no	DM-LS
iso-LCA+stool	PDGF-bb	iso-LCA+stool-CDCA+blood-Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-LS
iso-LCA+stool	PDGF-bb	iso-LCA+stool+Phenylacetic acid+stool+Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-LS
iso-LCA+stool	PDGF-bb	iso-LCA+stool-18:3n6+blood+L-Alanine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-LS
iso-LCA+stool	PDGF-bb	iso-LCA+stool-CDCA+blood-MUFA+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-LS
iso-LCA+stool	PDGF-bb	iso-LCA+stool-TCA+stool-L-Tryptophan+urine+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	PDGF-bb	2-methyl-butyric acid m-C4+blood-CA+blood-Cysteine+blood-PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.262	0.111	no	no	no	no	no	no	DM-LS
DCA+blood	PDGF-bb	DCA+blood+EPA+blood+n3+blood-L-Tryptophan+urine+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.122	0.111	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	PDGF-bb	3-(3-Hydroxyphenyl)propanoic acid+stool-16:0/18:0-PC+blood+18:0-LPC+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.33	0.111	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	PDGF-bb	3-(3-Hydroxyphenyl)propanoic acid+stool-16:0/18:0-PC+blood-16:1+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.33	0.111	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	PDGF-bb	3-(3-Hydroxyphenyl)propanoic acid+stool-16:0/18:0-PC+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.33	0.111	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	PDGF-bb	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.33	0.111	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	PDGF-bb	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+Cysteine+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.33	0.111	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	PDGF-bb	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.33	0.111	no	no	no	no	no	no	DM-LS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	PDGF-bb	"3-(3,4-dihydroxyphenyl)propionic acid+urine+L-Phenylalanine+urine+L-Tryptophan+urine+PDGF-bb"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.111	up	up	no	no	no	no	DM-LS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	PDGF-bb	"3-(3,4-dihydroxyphenyl)propionic acid+urine+3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine+PDGF-bb"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.111	up	up	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	PDGF-bb	Indole-3-Acetic acid+stool+L-Tyrosine+stool-16:1+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.304	0.111	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	PDGF-bb	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+Cysteine+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.304	0.111	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	PDGF-bb	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+Cysteine+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.304	0.111	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	PDGF-bb	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-18:0-LPE+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.304	0.111	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	PDGF-bb	Indole-3-Acetic acid+stool+L-Tyrosine+stool-18:0-LPE+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.304	0.111	no	no	no	no	no	no	DM-LS
TCA+stool	PDGF-bb	TCA+stool-L-Tryptophan+urine+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	DM-LS
HDCA+stool	PDGF-bb	HDCA+stool-16:0-LPC+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.176	0.111	no	no	no	no	no	no	DM-LS
Lachnospira	PDGF-bb	Lachnospira+16:0/18:2-PC+blood+Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-LS
Lachnospira	PDGF-bb	Lachnospira+18:0/18:2-PC+blood+Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-LS
Lachnospira	PDGF-bb	Lachnospira+18:1/16:0-PC+blood+Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-LS
Lachnospira	PDGF-bb	Lachnospira-d18:0-24:1-SM+blood+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-LS
Lachnospira	PDGF-bb	Lachnospira-d18:1-16:1-SM+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-LS
Lachnospira	PDGF-bb	Lachnospira-d18:1-14:0-SM+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-LS
Lachnospira	PDGF-bb	Lachnospira+16:0/18:2-PC+blood-d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-LS
Lachnospira	PDGF-bb	Lachnospira-d18:0-24:1-SM+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-LS
Lachnospira	PDGF-bb	Lachnospira+16:0/20:4-PC+blood-d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-LS
Lachnospira	PDGF-bb	Lachnospira+18:1/16:0-PC+blood-d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-LS
Lachnospira	PDGF-bb	Lachnospira+20:3/16:0-PC+blood-d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-LS
Lachnospira	PDGF-bb	Lachnospira-Adherens junction+Hematopoietic cell lineage-PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-LS
Lachnospira	PDGF-bb	Lachnospira-d18:1-16:1-SM+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-LS
Lachnospira	PDGF-bb	Lachnospira-d18:1-14:0-SM+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-LS
Lachnospira	PDGF-bb	Lachnospira+16:0/18:2-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-LS
Lachnospira	PDGF-bb	Lachnospira-d18:0-24:1-SM+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-LS
Lachnospira	PDGF-bb	Lachnospira+18:1/16:0-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+16:0/20:3-PC+blood+20:3/16:0-PC+blood-d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+16:0/20:3-PC+blood+16:0/20:4-PC+blood-d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+16:0/20:3-PC+blood+18:1/16:0-PC+blood-d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+nutriCA+stool-n3+blood-L-Tryptophan+urine+PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium-DCA+stool-20:3/18:0-PC+blood-L-Tryptophan+urine+PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium-DCA+stool-TCA+stool-L-Tryptophan+urine+PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+16:0/20:3-PC+blood+20:3-LPC+blood+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+18:1/18:1-PC+blood+20:3-LPC+blood+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+16:0/20:3-PC+blood+20:2/18:0-PC+blood+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+18:1/18:1-PC+blood+20:2/18:0-PC+blood+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+16:0/20:3-PC+blood+18:0/20:3-PC+blood+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+16:0/20:3-PC+blood+20:3-LPC+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+18:1/18:1-PC+blood+20:3-LPC+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+16:0/20:3-PC+blood+18:0/20:3-PC+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+16:0/20:3-PC+blood+18:1/16:0-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+16:0/20:3-PC+blood+18:0/16:0-PC+blood+Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+nutriCA+stool+CA+blood-Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+18:1/18:1-PC+blood-CDCA+blood-Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+16:0/20:3-PC+blood+20:2+blood+Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+18:1/18:1-PC+blood+20:2+blood+Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+nutriCA+stool-Phenylacetic acid+stool+Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+16:0/20:3-PC+blood+18:0/18:2-PC+blood+Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium-DCA+stool-18:0/18:2-PC+blood+Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+16:0/20:3-PC+blood+18:1/16:0-PC+blood+Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium-DCA+stool+HDCA+stool-16:0-LPC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+16:0/20:3-PC+blood+18:0/16:0-PC+blood+18:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+16:0/20:3-PC+blood+18:0/16:0-PC+blood+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+18:1/18:1-PC+blood-CDCA+blood-MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium+nutriCA+stool+HCA+blood-MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
Fusobacterium	PDGF-bb	Fusobacterium-DCA+stool+18:1/18:1-PE+blood+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.628	0.111	no	no	no	no	no	no	DM-LS
isobutyric acid C4+blood	PDGF-bb	isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b-PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.0151	0.111	up	up	no	no	no	no	DM-LS
isobutyric acid C4+blood	PDGF-bb	isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.0151	0.111	up	up	no	no	no	no	DM-LS
GCDCA+stool	PDGF-bb	GCDCA+stool+18:0/18:1-PC+blood+L-Alanine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-LS
GCDCA+stool	PDGF-bb	GCDCA+stool-Creatinine+blood-L-Alanine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-LS
GCDCA+stool	PDGF-bb	GCDCA+stool-Creatinine+blood+Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-LS
GCDCA+stool	PDGF-bb	GCDCA+stool+CA+blood-Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-LS
GCDCA+stool	PDGF-bb	GCDCA+stool+TCA+stool-L-Tryptophan+urine+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-LS
GCDCA+stool	PDGF-bb	GCDCA+stool+20:3/18:0-PC+blood-L-Tryptophan+urine+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-LS
GCDCA+stool	PDGF-bb	GCDCA+stool+18:0/18:0-PC+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-LS
GCDCA+stool	PDGF-bb	GCDCA+stool+18:0/18:1-PC+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-LS
GCDCA+stool	PDGF-bb	GCDCA+stool-Creatinine+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	PDGF-bb	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+Cysteine+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.111	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	PDGF-bb	5-Hydroxytryptamine+stool-Acetic acid+stool-Cysteine+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.111	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	PDGF-bb	5-Hydroxytryptamine+stool+L-Tyrosine+stool-16:1+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.111	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	PDGF-bb	5-Hydroxytryptamine+stool-Acetic acid+stool+Butyric acid+stool+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.111	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	PDGF-bb	5-Hydroxytryptamine+stool+L-Phenylalanine+stool-18:0-LPE+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.111	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	PDGF-bb	5-Hydroxytryptamine+stool+L-Tyrosine+stool-18:0-LPE+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.111	dn	dn	no	no	no	no	DM-LS
Odoribacter	PDGF-bb	Odoribacter-14:0/16:0-PC+blood+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.798	0.111	no	no	no	no	no	no	DM-LS
Odoribacter	PDGF-bb	Odoribacter-d18:0-24:1-SM+blood+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.798	0.111	no	no	no	no	no	no	DM-LS
Odoribacter	PDGF-bb	Odoribacter-d18:0-24:1-SM+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.798	0.111	no	no	no	no	no	no	DM-LS
Odoribacter	PDGF-bb	Odoribacter-d18:0-24:1-SM+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.798	0.111	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	PDGF-bb	Isobutyric acid+stool+L-Tyrosine+stool-16:1+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.408	0.111	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	PDGF-bb	Isobutyric acid+stool+Phenylacetic acid+stool+Cysteine+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.408	0.111	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	PDGF-bb	Isobutyric acid+stool+L-Phenylalanine+stool+Cysteine+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.408	0.111	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	PDGF-bb	Isobutyric acid+stool+L-Tyrosine+stool-18:0-LPE+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.408	0.111	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	PDGF-bb	Isobutyric acid+stool+L-Phenylalanine+stool-18:0-LPE+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.408	0.111	no	no	no	no	no	no	DM-LS
2-hydroxyphenylacetic acid+urine	PDGF-bb	2-hydroxyphenylacetic acid+urine-L-Tryptophan+urine+PDGF-bb	Indirect	urine_cometabolism	serum_cytokines	0.763	0.111	no	no	no	no	no	no	DM-LS
Lachnobacterium	PDGF-bb	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b-PDGF-bb	Indirect	Genus	serum_cytokines	0.867	0.111	no	no	no	no	no	no	DM-LS
Lachnobacterium	PDGF-bb	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	Genus	serum_cytokines	0.867	0.111	no	no	no	no	no	no	DM-LS
Kynurenic acid+stool	PDGF-bb	Kynurenic acid+stool+L-Tyrosine+stool-18:0-LPE+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.037	0.111	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	PDGF-bb	Kynurenic acid+stool+L-Tyrosine+stool-16:1+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.037	0.111	dn	dn	no	no	no	no	DM-LS
L-Tryptophan+urine	PDGF-bb	L-Tryptophan+urine+PDGF-bb	Direct	urine_cometabolism	serum_cytokines	0.226	0.111	no	no	no	no	no	no	DM-LS
Anaerostipes	PDGF-bb	Anaerostipes-Insulin resistance+18:0-LPC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-LS
Anaerostipes	PDGF-bb	Anaerostipes-Hepatitis B+18:0-LPE+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-LS
Anaerostipes	PDGF-bb	Anaerostipes-TNF signaling pathway+16:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-LS
Anaerostipes	PDGF-bb	Anaerostipes-Hepatitis B+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-LS
Anaerostipes	PDGF-bb	Anaerostipes-Chronic myeloid leukemia+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-LS
Anaerostipes	PDGF-bb	Anaerostipes-Insulin resistance+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-LS
Anaerostipes	PDGF-bb	Anaerostipes-Neurotrophin signaling pathway+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-LS
Anaerostipes	PDGF-bb	Anaerostipes-Prostate cancer+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	DM-LS
TUDCA+stool	PDGF-bb	TUDCA+stool-UDCA+stool+18:3n6+blood+L-Alanine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.241	0.111	no	no	no	no	no	no	DM-LS
TUDCA+stool	PDGF-bb	TUDCA+stool-UDCA+stool+CDCA+blood-MUFA+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.241	0.111	no	no	no	no	no	no	DM-LS
TUDCA+stool	PDGF-bb	TUDCA+stool-UDCA+stool-16:0/18:0-PC+blood-16:1+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.241	0.111	no	no	no	no	no	no	DM-LS
TUDCA+stool	PDGF-bb	TUDCA+stool-UDCA+stool-16:0/22:6-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.241	0.111	no	no	no	no	no	no	DM-LS
TUDCA+stool	PDGF-bb	TUDCA+stool-UDCA+stool-16:0/18:2-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.241	0.111	no	no	no	no	no	no	DM-LS
TUDCA+stool	PDGF-bb	TUDCA+stool-UDCA+stool+d18:1-16:1-SM+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.241	0.111	no	no	no	no	no	no	DM-LS
TUDCA+stool	PDGF-bb	TUDCA+stool-UDCA+stool-16:0/18:2-PC+blood+Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.241	0.111	no	no	no	no	no	no	DM-LS
TUDCA+stool	PDGF-bb	TUDCA+stool-UDCA+stool+CDCA+blood-Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.241	0.111	no	no	no	no	no	no	DM-LS
TUDCA+stool	PDGF-bb	TUDCA+stool-UDCA+stool-16:0/18:2-PC+blood-d18:1-20:0-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.241	0.111	no	no	no	no	no	no	DM-LS
TUDCA+stool	PDGF-bb	TUDCA+stool-UDCA+stool+d18:1-16:1-SM+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.241	0.111	no	no	no	no	no	no	DM-LS
TUDCA+stool	PDGF-bb	TUDCA+stool-UDCA+stool-16:0/18:0-PC+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.241	0.111	no	no	no	no	no	no	DM-LS
TUDCA+stool	PDGF-bb	TUDCA+stool-UDCA+stool-16:0/18:0-PC+blood+18:0-LPC+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.241	0.111	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+L-Phenylalanine+stool+Cysteine+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+Phenylacetic acid+stool+Cysteine+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+L-Phenylalanine+stool-18:0-LPE+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+L-Tyrosine+stool-18:0-LPE+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool+L-Tyrosine+stool-16:1+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	DM-LS
Paraprevotella	PDGF-bb	Paraprevotella+d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	DM-LS
DL-Indole-3-lactic acid+urine	PDGF-bb	DL-Indole-3-lactic acid+urine+L-Phenylalanine+urine+L-Tryptophan+urine+PDGF-bb	Indirect	urine_cometabolism	serum_cytokines	0.00552	0.111	up	up	no	no	no	no	DM-LS
iso-LCA+blood	PDGF-bb	iso-LCA+blood+L-Proline+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.507	0.111	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	PDGF-bb	Phenylacetic acid+stool+Cysteine+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.785	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-GCA+stool+16:0/18:1-PC+blood+18:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-GCA+stool+18:0/16:0-PC+blood+18:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-GCA+stool+16:0/18:1-PC+blood+16:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-18:1-LPC+blood+20:2+blood+Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-18:2-LPE+blood+20:4/16:0-PE+blood-Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-18:2-LPE+blood+18:3-LPC+blood-Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-GCA+stool+16:0/18:1-PC+blood+Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-GCA+stool+18:0/16:0-PC+blood+Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-GCA+stool+TCA+stool-L-Tryptophan+urine+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger+L-Phenylalanine+blood+n3+blood-L-Tryptophan+urine+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-18:1-LPC+blood+20:0-LPC+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-18:2-LPE+blood+20:0-LPC+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-18:1-LPC+blood+20:0-LPC+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-18:2-LPE+blood+20:0-LPC+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-18:1-LPC+blood+d18:1-22:0-SM+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-18:2-LPE+blood+18:3-LPC+blood-MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-GCA+stool+16:0/18:1-PC+blood+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-GCA+stool+18:0/16:0-PC+blood+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-18:2-LPE+blood-capric acid C6+blood-L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
Gemmiger	PDGF-bb	Gemmiger-GCA+stool+16:0/18:3-PC+blood+L-Alanine+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	DM-LS
GDCA+stool	PDGF-bb	GDCA+stool+18:0/18:0-PC+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.656	0.111	no	no	no	no	no	no	DM-LS
GDCA+stool	PDGF-bb	GDCA+stool+18:0/18:1-PC+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.656	0.111	no	no	no	no	no	no	DM-LS
GDCA+stool	PDGF-bb	GDCA+stool+18:0/18:1-PC+blood+L-Alanine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.656	0.111	no	no	no	no	no	no	DM-LS
GDCA+stool	PDGF-bb	GDCA+stool+TCA+stool-L-Tryptophan+urine+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.656	0.111	no	no	no	no	no	no	DM-LS
GDCA+stool	PDGF-bb	GDCA+stool-L-Phenylalanine+urine+L-Tryptophan+urine+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.656	0.111	no	no	no	no	no	no	DM-LS
GDCA+stool	PDGF-bb	GDCA+stool+20:3/18:0-PC+blood-L-Tryptophan+urine+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.656	0.111	no	no	no	no	no	no	DM-LS
Methanobrevibacter	PDGF-bb	Methanobrevibacter+18:0-LPC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.629	0.111	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	PDGF-bb	L-Tyrosine+stool-16:1+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.44	0.111	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	PDGF-bb	L-Tyrosine+stool-18:0-LPE+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.44	0.111	no	no	no	no	no	no	DM-LS
CDCA+stool	PDGF-bb	CDCA+stool-L-Tyrosine+stool-16:1+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.663	0.111	no	no	no	no	no	no	DM-LS
CDCA+stool	PDGF-bb	CDCA+stool+TCA+stool-L-Tryptophan+urine+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.663	0.111	no	no	no	no	no	no	DM-LS
CDCA+stool	PDGF-bb	CDCA+stool+18:3n6+blood+L-Alanine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.663	0.111	no	no	no	no	no	no	DM-LS
CDCA+stool	PDGF-bb	CDCA+stool-16:0/22:6-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.663	0.111	no	no	no	no	no	no	DM-LS
CDCA+stool	PDGF-bb	CDCA+stool-L-Phenylalanine+stool-18:0-LPE+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.663	0.111	no	no	no	no	no	no	DM-LS
CDCA+stool	PDGF-bb	CDCA+stool-L-Tyrosine+stool-18:0-LPE+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.663	0.111	no	no	no	no	no	no	DM-LS
CDCA+stool	PDGF-bb	CDCA+stool+HCA+blood-MUFA+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.663	0.111	no	no	no	no	no	no	DM-LS
CDCA+stool	PDGF-bb	CDCA+stool-L-Phenylalanine+stool+Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.663	0.111	no	no	no	no	no	no	DM-LS
CDCA+stool	PDGF-bb	CDCA+stool-Phenylacetic acid+stool+Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.663	0.111	no	no	no	no	no	no	DM-LS
CDCA+stool	PDGF-bb	CDCA+stool-HDCA+stool-16:0-LPC+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.663	0.111	no	no	no	no	no	no	DM-LS
CA+stool	PDGF-bb	CA+stool-L-Phenylalanine+stool-18:0-LPE+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	DM-LS
CA+stool	PDGF-bb	CA+stool-L-Tyrosine+stool-18:0-LPE+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	DM-LS
CA+stool	PDGF-bb	CA+stool-L-Tyrosine+stool-16:1+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	DM-LS
CA+stool	PDGF-bb	CA+stool+TCA+stool-L-Tryptophan+urine+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	DM-LS
CA+stool	PDGF-bb	CA+stool-16:0/22:6-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	DM-LS
CA+stool	PDGF-bb	CA+stool+HCA+stool-18:1+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	DM-LS
CA+stool	PDGF-bb	CA+stool+CDCA+blood-MUFA+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	DM-LS
CA+stool	PDGF-bb	CA+stool+18:3n6+blood+L-Alanine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	DM-LS
CA+stool	PDGF-bb	CA+stool-HDCA+stool-16:0-LPC+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	DM-LS
CA+stool	PDGF-bb	CA+stool-Phenylacetic acid+stool+Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	DM-LS
CA+stool	PDGF-bb	CA+stool+CA+blood-Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	DM-LS
CA+stool	PDGF-bb	CA+stool+CDCA+blood-Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	DM-LS
CA+stool	PDGF-bb	CA+stool-L-Phenylalanine+stool+Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	DM-LS
CA+stool	PDGF-bb	CA+stool+HCA+stool-Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	DM-LS
Slackia	PDGF-bb	Slackia-Cysteine+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.94	0.111	no	no	no	no	no	no	DM-LS
HDCA+blood	PDGF-bb	HDCA+blood+L-Ornithine+blood+L-Proline+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.483	0.111	no	no	no	no	no	no	DM-LS
HDCA+blood	PDGF-bb	HDCA+blood+iso-LCA+blood+L-Proline+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.483	0.111	no	no	no	no	no	no	DM-LS
UDCA+stool	PDGF-bb	UDCA+stool+18:3n6+blood+L-Alanine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.266	0.111	no	no	no	no	no	no	DM-LS
UDCA+stool	PDGF-bb	UDCA+stool+CDCA+blood-MUFA+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.266	0.111	no	no	no	no	no	no	DM-LS
UDCA+stool	PDGF-bb	UDCA+stool-16:0/18:0-PC+blood-16:1+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.266	0.111	no	no	no	no	no	no	DM-LS
UDCA+stool	PDGF-bb	UDCA+stool-16:0/22:6-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.266	0.111	no	no	no	no	no	no	DM-LS
UDCA+stool	PDGF-bb	UDCA+stool-16:0/18:2-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.266	0.111	no	no	no	no	no	no	DM-LS
UDCA+stool	PDGF-bb	UDCA+stool+d18:1-16:1-SM+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.266	0.111	no	no	no	no	no	no	DM-LS
UDCA+stool	PDGF-bb	UDCA+stool-16:0/18:2-PC+blood+Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.266	0.111	no	no	no	no	no	no	DM-LS
UDCA+stool	PDGF-bb	UDCA+stool+CDCA+blood-Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.266	0.111	no	no	no	no	no	no	DM-LS
UDCA+stool	PDGF-bb	UDCA+stool-16:0/18:2-PC+blood-d18:1-20:0-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.266	0.111	no	no	no	no	no	no	DM-LS
UDCA+stool	PDGF-bb	UDCA+stool+d18:1-16:1-SM+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.266	0.111	no	no	no	no	no	no	DM-LS
UDCA+stool	PDGF-bb	UDCA+stool-16:0/18:0-PC+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.266	0.111	no	no	no	no	no	no	DM-LS
UDCA+stool	PDGF-bb	UDCA+stool-16:0/18:0-PC+blood+18:0-LPC+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.266	0.111	no	no	no	no	no	no	DM-LS
TDCA+stool	PDGF-bb	TDCA+stool+UDCA+stool+18:3n6+blood+L-Alanine+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.963	0.111	no	no	no	no	no	no	DM-LS
TDCA+stool	PDGF-bb	TDCA+stool+UDCA+stool+CDCA+blood-MUFA+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.963	0.111	no	no	no	no	no	no	DM-LS
TDCA+stool	PDGF-bb	TDCA+stool+UDCA+stool-16:0/18:0-PC+blood-16:1+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.963	0.111	no	no	no	no	no	no	DM-LS
TDCA+stool	PDGF-bb	TDCA+stool+UDCA+stool-16:0/22:6-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.963	0.111	no	no	no	no	no	no	DM-LS
TDCA+stool	PDGF-bb	TDCA+stool+UDCA+stool-16:0/18:2-PC+blood-d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.963	0.111	no	no	no	no	no	no	DM-LS
TDCA+stool	PDGF-bb	TDCA+stool+UDCA+stool+d18:1-16:1-SM+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.963	0.111	no	no	no	no	no	no	DM-LS
TDCA+stool	PDGF-bb	TDCA+stool+UDCA+stool-16:0/18:2-PC+blood+Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.963	0.111	no	no	no	no	no	no	DM-LS
TDCA+stool	PDGF-bb	TDCA+stool+UDCA+stool+CDCA+blood-Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.963	0.111	no	no	no	no	no	no	DM-LS
TDCA+stool	PDGF-bb	TDCA+stool+UDCA+stool-16:0/18:2-PC+blood-d18:1-20:0-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.963	0.111	no	no	no	no	no	no	DM-LS
TDCA+stool	PDGF-bb	TDCA+stool+UDCA+stool+d18:1-16:1-SM+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.963	0.111	no	no	no	no	no	no	DM-LS
TDCA+stool	PDGF-bb	TDCA+stool+UDCA+stool-16:0/18:0-PC+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.963	0.111	no	no	no	no	no	no	DM-LS
TDCA+stool	PDGF-bb	TDCA+stool+UDCA+stool-16:0/18:0-PC+blood+18:0-LPC+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.963	0.111	no	no	no	no	no	no	DM-LS
nutriCA+stool	PDGF-bb	nutriCA+stool-n3+blood-L-Tryptophan+urine+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.481	0.111	no	no	no	no	no	no	DM-LS
nutriCA+stool	PDGF-bb	nutriCA+stool+HCA+blood-MUFA+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.481	0.111	no	no	no	no	no	no	DM-LS
nutriCA+stool	PDGF-bb	nutriCA+stool+CA+blood-Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.481	0.111	no	no	no	no	no	no	DM-LS
nutriCA+stool	PDGF-bb	nutriCA+stool-Phenylacetic acid+stool+Cysteine+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.481	0.111	no	no	no	no	no	no	DM-LS
GDCA+blood	PDGF-bb	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-L-Tryptophan+urine+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.632	0.111	no	no	no	no	no	no	DM-LS
GDCA+blood	PDGF-bb	GDCA+blood+iso-LCA+blood+L-Proline+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.632	0.111	no	no	no	no	no	no	DM-LS
acetic acid C2+blood	PDGF-bb	acetic acid C2+blood-L-Alanine+blood+PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.000193	0.111	up	dn	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	PDGF-bb	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-1b-PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.117	0.111	no	no	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	PDGF-bb	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-13-PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.117	0.111	no	no	no	no	no	no	DM-LS
L-Phenylalanine+urine	PDGF-bb	L-Phenylalanine+urine+L-Tryptophan+urine+PDGF-bb	Indirect	urine_cometabolism	serum_cytokines	0.0908	0.111	no	up	no	no	no	no	DM-LS
Adlercreutzia	PDGF-bb	Adlercreutzia+18:0-LPC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.548	0.111	no	no	no	no	no	no	DM-LS
Clostridium	PDGF-bb	Clostridium-Butyric acid+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.925	0.111	no	no	no	no	no	no	DM-LS
 Clostridium	PDGF-bb	Clostridium+Butyric acid+stool+PDGF-bb	Indirect	Genus	serum_cytokines	NA	0.111	NA	NA	NA	no	no	no	DM-LS
Clostridium	PDGF-bb	Clostridium-Butyric acid+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.925	0.111	no	no	no	no	no	no	DM-LS
 Clostridium	PDGF-bb	Clostridium+Butyric acid+stool+PDGF-bb	Indirect	Genus	serum_cytokines	NA	0.111	NA	NA	NA	no	no	no	DM-LS
T-¦Á-MCA+stool	PDGF-bb	T-¦Á-MCA+stool-TCA+stool-L-Tryptophan+urine+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.48	0.111	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	PDGF-bb	12-ketoDCA+blood-20:0-LPC+blood+d18:1-20:0-SM+blood+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.517	0.111	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	PDGF-bb	12-ketoDCA+blood-20:0-LPC+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.517	0.111	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	PDGF-bb	12-ketoDCA+blood-20:4-LPC+blood+d18:1-22:1-SM+blood+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.517	0.111	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	PDGF-bb	12-ketoDCA+blood-20:4-LPC+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.517	0.111	no	no	no	no	no	no	DM-LS
Butyricicoccus	PDGF-bb	Butyricicoccus+Butyric acid+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.852	0.111	no	no	no	no	no	no	DM-LS
3-Hydroxy-L-kynurenine+urine	PDGF-bb	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine+PDGF-bb	Indirect	urine_cometabolism	serum_cytokines	0.401	0.111	no	no	no	no	no	no	DM-LS
Blautia	IL-8	Blautia-20:5/18:0-PC+blood-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-LS
Blautia	IL-8	Blautia-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-LS
Blautia	IL-8	Blautia+GCA+blood+FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-LS
Blautia	IL-8	Blautia-20:5/18:0-PC+blood-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-LS
Blautia	IL-8	Blautia-16:0/18:2-PC+blood+20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-LS
Blautia	IL-8	Blautia-18:1/16:0-PC+blood+20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-LS
Blautia	IL-8	Blautia-18:0/22:6-PC+blood+20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-LS
Blautia	IL-8	Blautia-12-ketoDCA+stool+18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-LS
Blautia	IL-8	Blautia-18:0/22:6-PC+blood+18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-LS
Blautia	IL-8	Blautia-16:0/22:6-PC+blood+18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-LS
Blautia	IL-8	Blautia-16:0/18:2-PC+blood+18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	DM-LS
Parabacteroides	IL-8	Parabacteroides-Glucagon signaling pathway+Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-8	Parabacteroides-Spliceosome+Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-8	Parabacteroides+Choline+blood-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-8	Parabacteroides-Glucagon signaling pathway+Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-8	Parabacteroides-Spliceosome+Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-8	Parabacteroides+Choline+blood-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-8	Parabacteroides-EGFR tyrosine kinase inhibitor resistance+Proteasome-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-8	Parabacteroides-Central carbon metabolism in cancer+18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-8	Parabacteroides-TCA+stool-16:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-8	Parabacteroides-GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-8	Parabacteroides-Insulin signaling pathway+L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-8	Parabacteroides-15-HETE+blood-20:1+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-8	Parabacteroides+20:0+blood-FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-8	Parabacteroides-Glucagon signaling pathway+Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-8	Parabacteroides-Spliceosome+Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-8	Parabacteroides+Choline+blood-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	DM-LS
Dorea	IL-8	Dorea-18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	DM-LS
Faecalibacterium	IL-8	Faecalibacterium-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.0039	0.579	no	dn	dn	no	no	no	DM-LS
TUDCA+blood	IL-8	TUDCA+blood+Eotaxin+IL-4-IL-8	Indirect	serum_bileacids	serum_cytokines	0.0282	0.579	no	no	dn	no	no	no	DM-LS
TUDCA+blood	IL-8	TUDCA+blood+Eotaxin-GM-CSF+IL-8	Indirect	serum_bileacids	serum_cytokines	0.0282	0.579	no	no	dn	no	no	no	DM-LS
TUDCA+blood	IL-8	TUDCA+blood+Eotaxin+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.0282	0.579	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	IL-8	isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF+IL-8	Indirect	serum_scfa	serum_cytokines	0.0458	0.579	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	IL-8	isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-4-IL-8	Indirect	serum_scfa	serum_cytokines	0.0458	0.579	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	IL-8	isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-17A-IL-8	Indirect	serum_scfa	serum_cytokines	0.0458	0.579	no	no	dn	no	no	no	DM-LS
Bacteroides	IL-8	Bacteroides+n3+blood-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.000267	0.579	dn	dn	up	no	no	no	DM-LS
Bacteroides	IL-8	Bacteroides+22:6n3+blood-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.000267	0.579	dn	dn	up	no	no	no	DM-LS
Bacteroides	IL-8	Bacteroides+n3+blood-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.000267	0.579	dn	dn	up	no	no	no	DM-LS
Bacteroides	IL-8	Bacteroides+22:6n3+blood-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.000267	0.579	dn	dn	up	no	no	no	DM-LS
Bacteroides	IL-8	Bacteroides-18:2/20:4-PC+blood+20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.000267	0.579	dn	dn	up	no	no	no	DM-LS
Bacteroides	IL-8	Bacteroides+3-(3-Hydroxyphenyl)propanoic acid+stool-20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.000267	0.579	dn	dn	up	no	no	no	DM-LS
Bacteroides	IL-8	Bacteroides+3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.000267	0.579	dn	dn	up	no	no	no	DM-LS
Bacteroides	IL-8	Bacteroides-GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.000267	0.579	dn	dn	up	no	no	no	DM-LS
Bacteroides	IL-8	Bacteroides+n3+blood-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.000267	0.579	dn	dn	up	no	no	no	DM-LS
Bacteroides	IL-8	Bacteroides+22:6n3+blood-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.000267	0.579	dn	dn	up	no	no	no	DM-LS
Propionic acid+stool	IL-8	Propionic acid+stool+18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	stool_scfa	serum_cytokines	0.0436	0.579	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IL-8	Propionic acid+stool+16:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_scfa	serum_cytokines	0.0436	0.579	dn	no	up	no	no	no	DM-LS
[Ruminococcus]	IL-8	[Ruminococcus]-FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	DM-LS
GUDCA+blood	IL-8	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.0766	0.579	no	no	dn	no	no	no	DM-LS
GUDCA+blood	IL-8	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-8	Indirect	serum_bileacids	serum_cytokines	0.0766	0.579	no	no	dn	no	no	no	DM-LS
GUDCA+blood	IL-8	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-4-IL-8	Indirect	serum_bileacids	serum_cytokines	0.0766	0.579	no	no	dn	no	no	no	DM-LS
Acetic acid+stool	IL-8	Acetic acid+stool-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_scfa	serum_cytokines	0.0656	0.579	dn	no	no	no	no	no	DM-LS
Alistipes	IL-8	Alistipes+12-ketoDCA+stool+18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	DM-LS
Butyricimonas	IL-8	Butyricimonas+20:5/18:0-PC+blood-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.17	0.579	no	no	no	no	no	no	DM-LS
Butyricimonas	IL-8	Butyricimonas+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.17	0.579	no	no	no	no	no	no	DM-LS
Butyricimonas	IL-8	Butyricimonas-Prion disease-18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.17	0.579	no	no	no	no	no	no	DM-LS
Butyricimonas	IL-8	Butyricimonas-Cardiac muscle contraction-18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.17	0.579	no	no	no	no	no	no	DM-LS
Butyricimonas	IL-8	Butyricimonas-Prion disease-20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.17	0.579	no	no	no	no	no	no	DM-LS
Butyricimonas	IL-8	Butyricimonas-Cardiac muscle contraction-20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.17	0.579	no	no	no	no	no	no	DM-LS
Butyricimonas	IL-8	Butyricimonas-GCA+blood+FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.17	0.579	no	no	no	no	no	no	DM-LS
Butyricimonas	IL-8	Butyricimonas+20:5/18:0-PC+blood-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.17	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Signaling pathways regulating pluripotency of stem cells+Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Colorectal cancer+Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Glioma+Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Long-term potentiation+Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Choline metabolism in cancer+Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Gastric cancer+Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-ErbB signaling pathway+Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Phosphatidylinositol signaling system+Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Hepatitis B-FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Insulin resistance-FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Prostate cancer-FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-NF-kappa B signaling pathway-FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Central carbon metabolism in cancer+18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Insulin resistance+20:1+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-DHA+blood-L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-MAPK signaling pathway-Salivary secretion+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Wnt signaling pathway-Salivary secretion+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-RNA degradation-Salivary secretion+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Phosphatidylinositol signaling system-Salivary secretion+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Hepatitis B+GPC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Long-term potentiation-20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Signaling pathways regulating pluripotency of stem cells+Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Colorectal cancer+Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Glioma+Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Long-term potentiation+Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Choline metabolism in cancer+Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Gastric cancer+Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-ErbB signaling pathway+Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Phosphatidylinositol signaling system+Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Signaling pathways regulating pluripotency of stem cells+Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Colorectal cancer+Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Glioma+Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Long-term potentiation+Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Choline metabolism in cancer+Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Gastric cancer+Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-ErbB signaling pathway+Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
Collinsella	IL-8	Collinsella-Phosphatidylinositol signaling system+Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	IL-8	total_blood_scfa+blood+TUDCA+blood+Eotaxin+IL-4-IL-8	Indirect	serum_scfa	serum_cytokines	0.168	0.579	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	IL-8	total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-8	Indirect	serum_scfa	serum_cytokines	0.168	0.579	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	IL-8	total_blood_scfa+blood+TUDCA+blood+Eotaxin+IL-17A-IL-8	Indirect	serum_scfa	serum_cytokines	0.168	0.579	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-8	[Eubacterium]-Viral myocarditis-L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.0692	0.579	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-8	[Eubacterium]-Viral myocarditis-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.0692	0.579	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-8	[Eubacterium]-Viral myocarditis-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.0692	0.579	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-8	[Eubacterium]-Pathogenic Escherichia coli infection-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.0692	0.579	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-8	[Eubacterium]-Phagosome-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.0692	0.579	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-8	[Eubacterium]-Viral myocarditis-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.0692	0.579	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-8	[Eubacterium]-Pathogenic Escherichia coli infection-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.0692	0.579	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-8	[Eubacterium]-Phagosome-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.0692	0.579	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-8	[Eubacterium]-Salmonella infection+FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.0692	0.579	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-8	[Eubacterium]-Viral myocarditis-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.0692	0.579	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-8	[Eubacterium]-Pathogenic Escherichia coli infection-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.0692	0.579	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-8	[Eubacterium]-Phagosome-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.0692	0.579	no	no	no	no	no	no	DM-LS
LCA+stool	IL-8	LCA+stool-ACA+blood-Eotaxin+IL-4-IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	DM-LS
LCA+stool	IL-8	LCA+stool-ACA+blood-Eotaxin+IL-17A-IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	DM-LS
LCA+stool	IL-8	LCA+stool-ACA+blood-Eotaxin-GM-CSF+IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	DM-LS
LCA+stool	IL-8	LCA+stool-Cystine+blood+L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	DM-LS
LCA+stool	IL-8	LCA+stool-TCA+stool-16:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	DM-LS
LCA+stool	IL-8	LCA+stool-UDCA+stool-20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	DM-LS
LCA+stool	IL-8	LCA+stool-UDCA+stool-18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	DM-LS
LCA+stool	IL-8	LCA+stool-nutriCA+stool-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	DM-LS
Akkermansia	IL-8	Akkermansia+18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	DM-LS
Bifidobacterium	IL-8	Bifidobacterium-FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.105	0.579	no	dn	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Type I diabetes mellitus-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Endocytosis-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Allograft rejection-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Graft-versus-host disease-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Cell adhesion molecules-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Autoimmune thyroid disease-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Cell adhesion molecules-L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Type I diabetes mellitus-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Endocytosis-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Allograft rejection-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+22:6n3+blood-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Graft-versus-host disease-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Phagosome-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Cell adhesion molecules-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Autoimmune thyroid disease-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Type I diabetes mellitus-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Endocytosis-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Allograft rejection-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+22:6n3+blood-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Graft-versus-host disease-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Phagosome-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Cell adhesion molecules-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Autoimmune thyroid disease-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Type I diabetes mellitus-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Endocytosis-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Allograft rejection-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+22:6n3+blood-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Graft-versus-host disease-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Phagosome-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Cell adhesion molecules-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-8	Ruminococcus+Autoimmune thyroid disease-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	DM-LS
GCDCA+blood	IL-8	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4-IL-8	Indirect	serum_bileacids	serum_cytokines	0.31	0.579	no	no	no	no	no	no	DM-LS
GCDCA+blood	IL-8	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.31	0.579	no	no	no	no	no	no	DM-LS
GCDCA+blood	IL-8	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-8	Indirect	serum_bileacids	serum_cytokines	0.31	0.579	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-8	Succinivibrio-L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.138	0.579	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-8	Succinivibrio-L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.138	0.579	no	no	no	no	no	no	DM-LS
ACA+blood	IL-8	ACA+blood-Eotaxin+IL-4-IL-8	Indirect	serum_bileacids	serum_cytokines	0.338	0.579	no	no	no	no	no	no	DM-LS
ACA+blood	IL-8	ACA+blood-Eotaxin+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.338	0.579	no	no	no	no	no	no	DM-LS
ACA+blood	IL-8	ACA+blood-Eotaxin-GM-CSF+IL-8	Indirect	serum_bileacids	serum_cytokines	0.338	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool-UFA%+blood-Eotaxin-GM-CSF+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool-ACA+blood-Eotaxin-GM-CSF+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool-18:1/18:0-PC+blood+20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool-18:0/18:2-PC+blood+20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool-GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool-Cystine+blood+L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool+18:0/18:0-PS+blood+18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool-GDCA+stool-18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool+16:0/18:0-PS+blood+18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool+Propionic acid+stool+18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool+18:0/18:0-PS+blood-18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool+16:0/18:0-PS+blood-18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool-18:0/18:2-PC+blood+18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool+iso-LCA+stool+Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool-16:0/20:3-PC+blood-16:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool+Propionic acid+stool+16:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool-TCA+stool-16:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool-UFA%+blood-Eotaxin+IL-4-IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool-ACA+blood-Eotaxin+IL-4-IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool-UFA%+blood-Eotaxin+IL-17A-IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
DCA+stool	IL-8	DCA+stool-ACA+blood-Eotaxin+IL-17A-IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-8	Butyric acid+stool-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_scfa	serum_cytokines	0.102	0.579	dn	no	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	IL-8	4-hydroxybenzoic acid+stool-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.579	no	dn	no	no	no	no	DM-LS
GCA+blood	IL-8	GCA+blood+FGF basic+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.16	0.579	no	no	no	no	no	no	DM-LS
ACA+stool	IL-8	ACA+stool+GPC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.417	0.579	no	no	no	no	no	no	DM-LS
CDCA+blood	IL-8	CDCA+blood-Cysteine+blood+L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	serum_bileacids	serum_cytokines	0.506	0.579	no	no	no	no	no	no	DM-LS
CDCA+blood	IL-8	CDCA+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-8	Indirect	serum_bileacids	serum_cytokines	0.506	0.579	no	no	no	no	no	no	DM-LS
CDCA+blood	IL-8	CDCA+blood-Cysteine+blood-Eotaxin-GM-CSF+IL-8	Indirect	serum_bileacids	serum_cytokines	0.506	0.579	no	no	no	no	no	no	DM-LS
CDCA+blood	IL-8	CDCA+blood-MUFA%+blood-Eotaxin+IL-4-IL-8	Indirect	serum_bileacids	serum_cytokines	0.506	0.579	no	no	no	no	no	no	DM-LS
CDCA+blood	IL-8	CDCA+blood-Cysteine+blood-Eotaxin+IL-4-IL-8	Indirect	serum_bileacids	serum_cytokines	0.506	0.579	no	no	no	no	no	no	DM-LS
CDCA+blood	IL-8	CDCA+blood-MUFA%+blood-Eotaxin+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.506	0.579	no	no	no	no	no	no	DM-LS
CDCA+blood	IL-8	CDCA+blood-Cysteine+blood-Eotaxin+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.506	0.579	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-8	capric acid C6+blood+UFA%+blood-Eotaxin+IL-17A-IL-8	Indirect	serum_scfa	serum_cytokines	0.433	0.579	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-8	capric acid C6+blood+TUDCA+blood+Eotaxin+IL-17A-IL-8	Indirect	serum_scfa	serum_cytokines	0.433	0.579	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-8	capric acid C6+blood+MUFA%+blood-Eotaxin+IL-17A-IL-8	Indirect	serum_scfa	serum_cytokines	0.433	0.579	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-8	capric acid C6+blood-Sarcosine+blood-FGF basic+IL-17A-IL-8	Indirect	serum_scfa	serum_cytokines	0.433	0.579	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-8	capric acid C6+blood-L-Alanine+blood-FGF basic+IL-17A-IL-8	Indirect	serum_scfa	serum_cytokines	0.433	0.579	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-8	capric acid C6+blood+UFA%+blood-Eotaxin+IL-4-IL-8	Indirect	serum_scfa	serum_cytokines	0.433	0.579	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-8	capric acid C6+blood+TUDCA+blood+Eotaxin+IL-4-IL-8	Indirect	serum_scfa	serum_cytokines	0.433	0.579	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-8	capric acid C6+blood+MUFA%+blood-Eotaxin+IL-4-IL-8	Indirect	serum_scfa	serum_cytokines	0.433	0.579	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-8	capric acid C6+blood+UFA%+blood-Eotaxin-GM-CSF+IL-8	Indirect	serum_scfa	serum_cytokines	0.433	0.579	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-8	capric acid C6+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-8	Indirect	serum_scfa	serum_cytokines	0.433	0.579	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-8	capric acid C6+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-8	Indirect	serum_scfa	serum_cytokines	0.433	0.579	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-8	Pyramidobacter+Insulin resistance-FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.45	0.579	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-8	"Pyramidobacter+Parathyroid hormone synthesis, secretion and action-FGF basic+IL-17A-IL-8"	Indirect	Genus	serum_cytokines	0.45	0.579	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-8	Pyramidobacter-Carbon metabolism+FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.45	0.579	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-8	Pyramidobacter+Small cell lung cancer-FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.45	0.579	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-8	Pyramidobacter+Prostate cancer-FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.45	0.579	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-8	Pyramidobacter-Carbon metabolism-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.45	0.579	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-8	Pyramidobacter+Glucagon signaling pathway+Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.45	0.579	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-8	Pyramidobacter-Carbon metabolism-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.45	0.579	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-8	Pyramidobacter+Glucagon signaling pathway+Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.45	0.579	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-8	Pyramidobacter-Carbon metabolism-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.45	0.579	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-8	Pyramidobacter+Glucagon signaling pathway+Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.45	0.579	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-8	Pyramidobacter+Insulin resistance+20:1+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.45	0.579	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-8	"Pyramidobacter+Parathyroid hormone synthesis, secretion and action+Salivary secretion+IL-1ra+IL-8"	Indirect	Genus	serum_cytokines	0.45	0.579	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-8	Pyramidobacter-Carbon metabolism+18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.45	0.579	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-8	Pyramidobacter+Pathways in cancer+Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.45	0.579	no	no	no	no	no	no	DM-LS
Prevotella	IL-8	Prevotella-Proteasome-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	DM-LS
TCA+blood	IL-8	TCA+blood+FGF basic+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.339	0.579	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-8	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.38	0.579	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-8	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.38	0.579	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-8	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.38	0.579	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-8	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin-GM-CSF+IL-8	Indirect	serum_bileacids	serum_cytokines	0.38	0.579	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-8	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-8	Indirect	serum_bileacids	serum_cytokines	0.38	0.579	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-8	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-8	Indirect	serum_bileacids	serum_cytokines	0.38	0.579	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-8	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin+IL-4-IL-8	Indirect	serum_bileacids	serum_cytokines	0.38	0.579	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-8	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin+IL-4-IL-8	Indirect	serum_bileacids	serum_cytokines	0.38	0.579	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-8	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin+IL-4-IL-8	Indirect	serum_bileacids	serum_cytokines	0.38	0.579	no	no	no	no	no	no	DM-LS
HCA+stool	IL-8	HCA+stool-18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.155	0.579	no	no	no	no	no	no	DM-LS
HCA+stool	IL-8	HCA+stool-GPC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.155	0.579	no	no	no	no	no	no	DM-LS
Roseburia	IL-8	Roseburia-20:1+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.495	0.579	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	IL-8	12-ketoDCA+stool+18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.505	0.579	no	no	no	no	no	no	DM-LS
GLCA+blood	IL-8	GLCA+blood-Sarcosine+blood-FGF basic+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.319	0.579	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	IL-8	L-Tryptophan+stool+Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.557	0.579	no	no	no	no	no	no	DM-LS
CA+blood	IL-8	CA+blood+Eotaxin-GM-CSF+IL-8	Indirect	serum_bileacids	serum_cytokines	0.606	0.579	no	no	no	no	no	no	DM-LS
CA+blood	IL-8	CA+blood+Eotaxin+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.606	0.579	no	no	no	no	no	no	DM-LS
CA+blood	IL-8	CA+blood+Eotaxin+IL-4-IL-8	Indirect	serum_bileacids	serum_cytokines	0.606	0.579	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IL-8	L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.398	0.579	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	IL-8	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin+IL-17A-IL-8	Indirect	serum_scfa	serum_cytokines	0.407	0.579	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	IL-8	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-8	Indirect	serum_scfa	serum_cytokines	0.407	0.579	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	IL-8	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin+IL-4-IL-8	Indirect	serum_scfa	serum_cytokines	0.407	0.579	no	no	no	no	no	no	DM-LS
GCA+stool	IL-8	GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0809	0.579	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	IL-8	T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-8	Indirect	serum_bileacids	serum_cytokines	0.478	0.579	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	IL-8	T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4-IL-8	Indirect	serum_bileacids	serum_cytokines	0.478	0.579	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	IL-8	T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.478	0.579	no	no	no	no	no	no	DM-LS
Coprococcus	IL-8	Coprococcus-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	DM-LS
Coprococcus	IL-8	Coprococcus-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	DM-LS
Coprococcus	IL-8	Coprococcus-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	DM-LS
Oscillospira	IL-8	Oscillospira-Adrenergic signaling in cardiomyocytes+Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-LS
Oscillospira	IL-8	Oscillospira+Peroxisome-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-LS
Oscillospira	IL-8	Oscillospira+Peroxisome+18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-LS
Oscillospira	IL-8	Oscillospira+Peroxisome+18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-LS
Oscillospira	IL-8	Oscillospira-Alzheimer disease-18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-LS
Oscillospira	IL-8	Oscillospira+Peroxisome+20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-LS
Oscillospira	IL-8	Oscillospira-Alzheimer disease-20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-LS
Oscillospira	IL-8	Oscillospira-CDCA+stool-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-LS
Oscillospira	IL-8	Oscillospira-nutriCA+stool-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-LS
Oscillospira	IL-8	Oscillospira-4-hydroxybenzoic acid+stool-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-LS
Oscillospira	IL-8	Oscillospira-Adrenergic signaling in cardiomyocytes+Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-LS
Oscillospira	IL-8	Oscillospira+Peroxisome-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-LS
Oscillospira	IL-8	Oscillospira-Adrenergic signaling in cardiomyocytes+Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-LS
Oscillospira	IL-8	Oscillospira+Peroxisome-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	DM-LS
HCA+blood	IL-8	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-8	Indirect	serum_bileacids	serum_cytokines	0.544	0.579	no	no	no	no	no	no	DM-LS
HCA+blood	IL-8	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.544	0.579	no	no	no	no	no	no	DM-LS
HCA+blood	IL-8	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin+IL-4-IL-8	Indirect	serum_bileacids	serum_cytokines	0.544	0.579	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-8	iso-LCA+stool+Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.72	0.579	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	IL-8	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin-GM-CSF+IL-8	Indirect	serum_scfa	serum_cytokines	0.262	0.579	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	IL-8	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin+IL-17A-IL-8	Indirect	serum_scfa	serum_cytokines	0.262	0.579	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	IL-8	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin+IL-4-IL-8	Indirect	serum_scfa	serum_cytokines	0.262	0.579	no	no	no	no	no	no	DM-LS
DCA+blood	IL-8	DCA+blood-MUFA%+blood-Eotaxin+IL-4-IL-8	Indirect	serum_bileacids	serum_cytokines	0.122	0.579	no	no	no	no	no	no	DM-LS
DCA+blood	IL-8	DCA+blood-MUFA%+blood-Eotaxin+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.122	0.579	no	no	no	no	no	no	DM-LS
DCA+blood	IL-8	DCA+blood-TCA+blood+FGF basic+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.122	0.579	no	no	no	no	no	no	DM-LS
DCA+blood	IL-8	DCA+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-8	Indirect	serum_bileacids	serum_cytokines	0.122	0.579	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-8	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.33	0.579	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-8	3-(3-Hydroxyphenyl)propanoic acid+stool-20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.33	0.579	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IL-8	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.304	0.579	no	no	no	no	no	no	DM-LS
TCA+stool	IL-8	TCA+stool-16:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.458	0.579	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-8	HDCA+stool-18:1/20:3-PC+blood+20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-8	HDCA+stool-16:0-LPC+blood+GPC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-8	HDCA+stool-nutriCA+stool-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-8	HDCA+stool+iso-LCA+stool+Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-8	HDCA+stool-16:0/20:3-PC+blood-16:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-8	HDCA+stool-16:0-LPC+blood-18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-8	HDCA+stool-18:0-LPA+blood-18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	DM-LS
Lachnospira	IL-8	Lachnospira+18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-LS
Lachnospira	IL-8	Lachnospira+20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	DM-LS
Fusobacterium	IL-8	Fusobacterium+16:0/20:3-PC+blood-16:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.628	0.579	no	no	no	no	no	no	DM-LS
Fusobacterium	IL-8	Fusobacterium+nutriCA+stool-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.628	0.579	no	no	no	no	no	no	DM-LS
Fusobacterium	IL-8	Fusobacterium+UFA%+blood-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.628	0.579	no	no	no	no	no	no	DM-LS
Fusobacterium	IL-8	Fusobacterium+MUFA%+blood-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.628	0.579	no	no	no	no	no	no	DM-LS
Fusobacterium	IL-8	Fusobacterium+UFA%+blood-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.628	0.579	no	no	no	no	no	no	DM-LS
Fusobacterium	IL-8	Fusobacterium+MUFA%+blood-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.628	0.579	no	no	no	no	no	no	DM-LS
Fusobacterium	IL-8	Fusobacterium+UFA%+blood-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.628	0.579	no	no	no	no	no	no	DM-LS
Fusobacterium	IL-8	Fusobacterium+MUFA%+blood-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.628	0.579	no	no	no	no	no	no	DM-LS
isobutyric acid C4+blood	IL-8	isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-8	Indirect	serum_scfa	serum_cytokines	0.0151	0.579	up	up	no	no	no	no	DM-LS
isobutyric acid C4+blood	IL-8	isobutyric acid C4+blood+MUFA%+blood-Eotaxin+IL-17A-IL-8	Indirect	serum_scfa	serum_cytokines	0.0151	0.579	up	up	no	no	no	no	DM-LS
isobutyric acid C4+blood	IL-8	isobutyric acid C4+blood+MUFA%+blood-Eotaxin+IL-4-IL-8	Indirect	serum_scfa	serum_cytokines	0.0151	0.579	up	up	no	no	no	no	DM-LS
GCDCA+stool	IL-8	GCDCA+stool-Creatinine+blood-Eotaxin-GM-CSF+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IL-8	GCDCA+stool+CA+blood+Eotaxin-GM-CSF+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IL-8	GCDCA+stool+TCA+stool-16:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IL-8	GCDCA+stool+18:0/18:0-PC+blood+20:1+blood-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IL-8	GCDCA+stool+18:0/18:1-PC+blood+20:1+blood-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IL-8	GCDCA+stool+18:0/18:0-PC+blood+L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IL-8	GCDCA+stool+18:0/18:1-PC+blood+L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IL-8	GCDCA+stool+GDCA+stool-18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IL-8	GCDCA+stool-Creatinine+blood-Eotaxin+IL-4-IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IL-8	GCDCA+stool+CA+blood+Eotaxin+IL-4-IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IL-8	GCDCA+stool-Creatinine+blood-Eotaxin+IL-17A-IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IL-8	GCDCA+stool+CA+blood+Eotaxin+IL-17A-IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool+L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool-Acetic acid+stool-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool-Propionic acid+stool+18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	DM-LS
Odoribacter	IL-8	Odoribacter+IL-8	Direct	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-8	Isobutyric acid+stool+Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_scfa	serum_cytokines	0.408	0.579	no	no	no	no	no	no	DM-LS
Lachnobacterium	IL-8	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.867	0.579	no	no	no	no	no	no	DM-LS
Lachnobacterium	IL-8	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.867	0.579	no	no	no	no	no	no	DM-LS
Lachnobacterium	IL-8	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.867	0.579	no	no	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-8	Kynurenic acid+stool-nutriCA+stool-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.037	0.579	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-8	Kynurenic acid+stool+L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.037	0.579	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-8	Kynurenic acid+stool-UDCA+stool-18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.037	0.579	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-8	Kynurenic acid+stool-UDCA+stool-20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.037	0.579	dn	dn	no	no	no	no	DM-LS
Anaerostipes	IL-8	Anaerostipes+15-HETE+blood-20:1+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-8	Anaerostipes-Insulin resistance+20:1+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-8	Anaerostipes-3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-8	Anaerostipes-Hepatitis B+GPC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-8	Anaerostipes-3-(3-Hydroxyphenyl)propanoic acid+stool-20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-8	Anaerostipes-Non-small cell lung cancer+Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-8	Anaerostipes+TUDCA+blood+Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-8	Anaerostipes-Hepatitis B-FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-8	Anaerostipes-Chronic myeloid leukemia-FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-8	Anaerostipes-Insulin resistance-FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-8	Anaerostipes-Prostate cancer-FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-8	Anaerostipes-Non-small cell lung cancer+Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-8	Anaerostipes+TUDCA+blood+Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-8	Anaerostipes-Non-small cell lung cancer+Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-8	Anaerostipes+TUDCA+blood+Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	DM-LS
TUDCA+stool	IL-8	TUDCA+stool-UDCA+stool-20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.241	0.579	no	no	no	no	no	no	DM-LS
TUDCA+stool	IL-8	TUDCA+stool-UDCA+stool-18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.241	0.579	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-8	Isovaleric acid+stool+Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_scfa	serum_cytokines	0.343	0.579	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-8	Paraprevotella+18:0/20:2-PC+blood-18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.118	0.579	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-8	Paraprevotella+18:0/20:2-PC+blood+20:1+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.118	0.579	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-8	Paraprevotella+d18:1-20:0-SM+blood+GPC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.118	0.579	no	no	no	no	no	no	DM-LS
iso-LCA+blood	IL-8	iso-LCA+blood-Sarcosine+blood-FGF basic+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.507	0.579	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	IL-8	Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.785	0.579	no	no	no	no	no	no	DM-LS
Gemmiger	IL-8	Gemmiger-GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	DM-LS
Gemmiger	IL-8	Gemmiger+DHA+blood-L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-8	GDCA+stool-18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.656	0.579	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IL-8	Methanobrevibacter+L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.629	0.579	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	IL-8	L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.44	0.579	no	no	no	no	no	no	DM-LS
CDCA+stool	IL-8	CDCA+stool-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.663	0.579	no	no	no	no	no	no	DM-LS
CA+stool	IL-8	CA+stool-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.827	0.579	no	no	no	no	no	no	DM-LS
CA+stool	IL-8	CA+stool-18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.827	0.579	no	no	no	no	no	no	DM-LS
CA+stool	IL-8	CA+stool-20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.827	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia+Platinum drug resistance+Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia-Neutrophil extracellular trap formation-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia-Cysteine+blood-Eotaxin+IL-4-IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia+Platinum drug resistance+Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia-Neutrophil extracellular trap formation-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia-Cysteine+blood-Eotaxin-GM-CSF+IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia+Primary immunodeficiency+FGF basic+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia+Platinum drug resistance+Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia-Neutrophil extracellular trap formation-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia-Cysteine+blood-Eotaxin+IL-17A-IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia-16:0/22:6-PE+blood-L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia-Cysteine+blood+L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia-Cystine+blood+L-2-Aminobutyric acid+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia-16:0/22:6-PE+blood+18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia+Platinum drug resistance-18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia-cGMP-PKG signaling pathway+18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia-PPAR signaling pathway+18:0/22:6-PE+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia-16:0/22:6-PE+blood-20:1+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
Slackia	IL-8	Slackia-15-HETE+blood-20:1+blood-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.94	0.579	no	no	no	no	no	no	DM-LS
HDCA+blood	IL-8	HDCA+blood-Sarcosine+blood-FGF basic+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.483	0.579	no	no	no	no	no	no	DM-LS
UDCA+stool	IL-8	UDCA+stool-20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.266	0.579	no	no	no	no	no	no	DM-LS
UDCA+stool	IL-8	UDCA+stool-18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.266	0.579	no	no	no	no	no	no	DM-LS
TDCA+stool	IL-8	TDCA+stool+UDCA+stool-20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.963	0.579	no	no	no	no	no	no	DM-LS
TDCA+stool	IL-8	TDCA+stool+UDCA+stool-18:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.963	0.579	no	no	no	no	no	no	DM-LS
nutriCA+stool	IL-8	nutriCA+stool-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.481	0.579	no	no	no	no	no	no	DM-LS
GDCA+blood	IL-8	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.632	0.579	no	no	no	no	no	no	DM-LS
GDCA+blood	IL-8	GDCA+blood+iso-LCA+blood-Sarcosine+blood-FGF basic+IL-17A-IL-8	Indirect	serum_bileacids	serum_cytokines	0.632	0.579	no	no	no	no	no	no	DM-LS
GDCA+blood	IL-8	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-4-IL-8	Indirect	serum_bileacids	serum_cytokines	0.632	0.579	no	no	no	no	no	no	DM-LS
GDCA+blood	IL-8	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF+IL-8	Indirect	serum_bileacids	serum_cytokines	0.632	0.579	no	no	no	no	no	no	DM-LS
acetic acid C2+blood	IL-8	acetic acid C2+blood-L-Alanine+blood-FGF basic+IL-17A-IL-8	Indirect	serum_scfa	serum_cytokines	0.000193	0.579	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	IL-8	acetic acid C2+blood-Sarcosine+blood-FGF basic+IL-17A-IL-8	Indirect	serum_scfa	serum_cytokines	0.000193	0.579	up	dn	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	IL-8	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-4-IL-8	Indirect	serum_scfa	serum_cytokines	0.117	0.579	no	no	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	IL-8	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-8	Indirect	serum_scfa	serum_cytokines	0.117	0.579	no	no	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	IL-8	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-17A-IL-8	Indirect	serum_scfa	serum_cytokines	0.117	0.579	no	no	no	no	no	no	DM-LS
Adlercreutzia	IL-8	Adlercreutzia-16:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.548	0.579	no	no	no	no	no	no	DM-LS
Clostridium	IL-8	Clostridium-20:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.925	0.579	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-8	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+IL-1ra+IL-8	Indirect	stool_bileacids	serum_cytokines	0.48	0.579	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-8	12-ketoDCA+blood-20:0-LPC+blood+20:1+blood-IL-1ra+IL-8	Indirect	serum_bileacids	serum_cytokines	0.517	0.579	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-8	Butyricicoccus-Phenylacetic acid+stool-IL-1ra+IL-8	Indirect	Genus	serum_cytokines	0.852	0.579	no	no	no	no	no	no	DM-LS
Blautia	Resistin	Blautia-12-ketoDCA+stool-Glycine+blood-Resistin	Indirect	Genus	DM-associated hormones	1.36E-05	0.156	up	dn	dn	no	no	no	DM-LS
Blautia	Resistin	Blautia-12-ketoDCA+stool+DCA+stool+Resistin	Indirect	Genus	DM-associated hormones	1.36E-05	0.156	up	dn	dn	no	no	no	DM-LS
Blautia	Resistin	Blautia-12-ketoDCA+stool+LCA+stool+Resistin	Indirect	Genus	DM-associated hormones	1.36E-05	0.156	up	dn	dn	no	no	no	DM-LS
Blautia	Resistin	Blautia-20:5/18:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	1.36E-05	0.156	up	dn	dn	no	no	no	DM-LS
Blautia	Resistin	Blautia-16:0/22:6-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	1.36E-05	0.156	up	dn	dn	no	no	no	DM-LS
Blautia	Resistin	Blautia-16:0/18:2-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	1.36E-05	0.156	up	dn	dn	no	no	no	DM-LS
Blautia	Resistin	Blautia+d18:0-24:1-SM+blood+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	1.36E-05	0.156	up	dn	dn	no	no	no	DM-LS
Blautia	Resistin	Blautia-18:1/16:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	1.36E-05	0.156	up	dn	dn	no	no	no	DM-LS
Blautia	Resistin	Blautia-18:0/22:6-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	1.36E-05	0.156	up	dn	dn	no	no	no	DM-LS
Parabacteroides	Resistin	Parabacteroides-GCA+stool-Resistin	Indirect	Genus	DM-associated hormones	4.19E-05	0.156	no	up	up	no	no	no	DM-LS
Dorea	Resistin	Dorea+d18:1-20:0-SM+blood+GPC+blood+Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	DM-LS
Dorea	Resistin	Dorea-18:0/22:6-PE+blood+IL-1ra+Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	DM-LS
Faecalibacterium	Resistin	Faecalibacterium-16:1/16:1-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0039	0.156	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	Resistin	Faecalibacterium-16:0/18:2-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0039	0.156	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	Resistin	Faecalibacterium-Phenylacetic acid+stool-IL-1ra+Resistin	Indirect	Genus	DM-associated hormones	0.0039	0.156	no	dn	dn	no	no	no	DM-LS
TUDCA+blood	Resistin	TUDCA+blood+Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.156	no	no	dn	no	no	no	DM-LS
TUDCA+blood	Resistin	TUDCA+blood+Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.156	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	DM-LS
Bacteroides	Resistin	Bacteroides-GCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	DM-LS
Propionic acid+stool	Resistin	Propionic acid+stool+18:0/20:4-PI+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.156	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	Resistin	Propionic acid+stool-Glycine+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.156	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	Resistin	Propionic acid+stool-ACA+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.156	dn	no	up	no	no	no	DM-LS
[Ruminococcus]	Resistin	[Ruminococcus]+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0679	0.156	no	no	dn	no	no	no	DM-LS
GUDCA+blood	Resistin	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.156	no	no	dn	no	no	no	DM-LS
GUDCA+blood	Resistin	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.156	no	no	dn	no	no	no	DM-LS
Acetic acid+stool	Resistin	Acetic acid+stool+18:3n6+blood+d18:1-16:0-SM+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.156	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	Resistin	Acetic acid+stool+Propionic acid+stool+18:0/20:4-PI+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.156	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	Resistin	Acetic acid+stool+Propionic acid+stool-Glycine+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.156	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	Resistin	Acetic acid+stool-Phenylacetic acid+stool-IL-1ra+Resistin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.156	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	Resistin	Acetic acid+stool+Propionic acid+stool-ACA+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.156	dn	no	no	no	no	no	DM-LS
Alistipes	Resistin	Alistipes+12-ketoDCA+stool+DCA+stool+Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-LS
Alistipes	Resistin	Alistipes+12-ketoDCA+stool+LCA+stool+Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-LS
Alistipes	Resistin	Alistipes+12-ketoDCA+stool-Glycine+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	DM-LS
Butyricimonas	Resistin	Butyricimonas-d18:0-24:1-SM+blood+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	DM-LS
Butyricimonas	Resistin	Butyricimonas+20:5/18:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	DM-LS
Butyricimonas	Resistin	Butyricimonas-d18:1-14:0-SM+blood+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	DM-LS
Collinsella	Resistin	Collinsella-18:0/20:4-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.128	0.156	no	no	no	no	no	no	DM-LS
Collinsella	Resistin	Collinsella-LCA+stool+Resistin	Indirect	Genus	DM-associated hormones	0.128	0.156	no	no	no	no	no	no	DM-LS
Collinsella	Resistin	Collinsella-AGE-RAGE signaling pathway in diabetic complications+Resistin	Indirect	Genus	DM-associated hormones	0.128	0.156	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	Resistin	total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	serum_scfa	DM-associated hormones	0.168	0.156	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	Resistin	total_blood_scfa+blood+TUDCA+blood+Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	serum_scfa	DM-associated hormones	0.168	0.156	no	no	no	no	no	no	DM-LS
[Eubacterium]	Resistin	[Eubacterium]-Yersinia infection+ACA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0692	0.156	no	no	no	no	no	no	DM-LS
[Eubacterium]	Resistin	[Eubacterium]-Fluid shear stress and atherosclerosis+ACA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0692	0.156	no	no	no	no	no	no	DM-LS
[Eubacterium]	Resistin	[Eubacterium]-Pathogenic Escherichia coli infection+ACA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0692	0.156	no	no	no	no	no	no	DM-LS
[Eubacterium]	Resistin	[Eubacterium]+p53 signaling pathway-ACA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0692	0.156	no	no	no	no	no	no	DM-LS
[Eubacterium]	Resistin	[Eubacterium]-Salmonella infection+ACA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0692	0.156	no	no	no	no	no	no	DM-LS
[Eubacterium]	Resistin	[Eubacterium]-Influenza A+ACA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0692	0.156	no	no	no	no	no	no	DM-LS
[Eubacterium]	Resistin	[Eubacterium]-Phagosome+ACA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0692	0.156	no	no	no	no	no	no	DM-LS
[Eubacterium]	Resistin	[Eubacterium]+p53 signaling pathway-Glycine+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0692	0.156	no	no	no	no	no	no	DM-LS
[Eubacterium]	Resistin	[Eubacterium]-Influenza A-GCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.0692	0.156	no	no	no	no	no	no	DM-LS
LCA+stool	Resistin	LCA+stool+Resistin	Direct	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	DM-LS
Akkermansia	Resistin	Akkermansia+LCA+stool+Resistin	Indirect	Genus	DM-associated hormones	0.23	0.156	no	no	no	no	no	no	DM-LS
Akkermansia	Resistin	Akkermansia-18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.23	0.156	no	no	no	no	no	no	DM-LS
Bifidobacterium	Resistin	Bifidobacterium+Glycine+blood-Resistin	Indirect	Genus	DM-associated hormones	0.105	0.156	no	dn	no	no	no	no	DM-LS
Ruminococcus	Resistin	Ruminococcus+Phagosome+ACA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.335	0.156	no	no	no	no	no	no	DM-LS
GCDCA+blood	Resistin	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.156	no	no	no	no	no	no	DM-LS
GCDCA+blood	Resistin	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-L-Phenylalanine+stool+20:3/18:0-PC+blood+ACA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-Phospholipase D signaling pathway+Chronic myeloid leukemia-ACA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-L-Phenylalanine+stool+20:3/18:0-PC+blood+Glycine+blood-Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-L-Tyrosine+stool-18:1/18:1-PE+blood-Glycine+blood-Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-Phospholipase D signaling pathway-Longevity regulating pathway - multiple species-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-Phospholipase D signaling pathway+Pancreatic secretion+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-L-Tyrosine+stool+20:5/18:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-L-Phenylalanine+stool+20:5/18:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-L-Tyrosine+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-L-Phenylalanine+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-L-Tyrosine+stool-18:3n6+blood+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-L-Phenylalanine+stool-18:3n6+blood+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-L-Tyrosine+stool+18:0/18:2-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-L-Phenylalanine+stool+18:0/18:2-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-Phospholipase D signaling pathway+Long-term depression+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-L-Tyrosine+stool+18:1/18:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-Phospholipase D signaling pathway+Cocaine addiction+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-Phospholipase D signaling pathway+Hepatitis B+GPC+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-Phospholipase D signaling pathway+Hepatitis C+GPC+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-L-Tyrosine+stool-18:0-LPE+blood+GPC+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-L-Phenylalanine+stool-18:0-LPE+blood+GPC+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-Phospholipase D signaling pathway+Neurotrophin signaling pathway+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-Phospholipase D signaling pathway-Longevity regulating pathway - multiple species-18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-Phospholipase D signaling pathway+Cushing syndrome+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-Phospholipase D signaling pathway+Hepatitis B+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-Phospholipase D signaling pathway+Relaxin signaling pathway+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-Phospholipase D signaling pathway+Chronic myeloid leukemia+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-Phospholipase D signaling pathway+TNF signaling pathway+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-Phospholipase D signaling pathway+Hepatitis C+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
Succinivibrio	Resistin	Succinivibrio-L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra+Resistin	Indirect	Genus	DM-associated hormones	0.138	0.156	no	no	no	no	no	no	DM-LS
ACA+blood	Resistin	ACA+blood-Resistin	Direct	serum_bileacids	DM-associated hormones	0.338	0.156	no	no	no	no	no	no	DM-LS
DCA+stool	Resistin	DCA+stool+Resistin	Direct	stool_bileacids	DM-associated hormones	0.195	0.156	no	no	no	no	no	no	DM-LS
Butyric acid+stool	Resistin	Butyric acid+stool+8-HETE+blood-ACA+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.102	0.156	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	Resistin	Butyric acid+stool+Propionic acid+stool-ACA+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.102	0.156	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	Resistin	Butyric acid+stool+Propionic acid+stool-Glycine+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.102	0.156	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	Resistin	Butyric acid+stool-16:1/16:1-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.102	0.156	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	Resistin	Butyric acid+stool+Propionic acid+stool+18:0/20:4-PI+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.102	0.156	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	Resistin	Butyric acid+stool-Phenylacetic acid+stool-IL-1ra+Resistin	Indirect	stool_scfa	DM-associated hormones	0.102	0.156	dn	no	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	Resistin	4-hydroxybenzoic acid+stool+ACA+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.156	no	dn	no	no	no	no	DM-LS
GCA+blood	Resistin	GCA+blood+FGF basic+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.156	no	no	no	no	no	no	DM-LS
ACA+stool	Resistin	ACA+stool+GPC+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.156	no	no	no	no	no	no	DM-LS
ACA+stool	Resistin	ACA+stool-GCA+stool-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.156	no	no	no	no	no	no	DM-LS
CDCA+blood	Resistin	CDCA+blood+d18:1-14:1-SM+blood+d18:1-16:0-SM+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.156	no	no	no	no	no	no	DM-LS
capric acid C6+blood	Resistin	capric acid C6+blood-d18:1-16:1-SM+blood+d18:1-20:0-SM+blood+GPC+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.433	0.156	no	no	no	no	no	no	DM-LS
capric acid C6+blood	Resistin	capric acid C6+blood-CDCA+blood+d18:1-14:1-SM+blood+d18:1-16:0-SM+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.433	0.156	no	no	no	no	no	no	DM-LS
Pyramidobacter	Resistin	Pyramidobacter+Insulin resistance+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.45	0.156	no	no	no	no	no	no	DM-LS
Pyramidobacter	Resistin	Pyramidobacter-Carbon metabolism-18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.45	0.156	no	no	no	no	no	no	DM-LS
Pyramidobacter	Resistin	Pyramidobacter+Small cell lung cancer+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.45	0.156	no	no	no	no	no	no	DM-LS
Pyramidobacter	Resistin	Pyramidobacter+Pathways in cancer+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.45	0.156	no	no	no	no	no	no	DM-LS
Pyramidobacter	Resistin	Pyramidobacter+Prostate cancer+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.45	0.156	no	no	no	no	no	no	DM-LS
Pyramidobacter	Resistin	Pyramidobacter+HDCA+stool+18:0/20:4-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.45	0.156	no	no	no	no	no	no	DM-LS
Pyramidobacter	Resistin	Pyramidobacter+Insulin resistance+AGE-RAGE signaling pathway in diabetic complications+Resistin	Indirect	Genus	DM-associated hormones	0.45	0.156	no	no	no	no	no	no	DM-LS
Pyramidobacter	Resistin	Pyramidobacter+HDCA+stool+LCA+stool+Resistin	Indirect	Genus	DM-associated hormones	0.45	0.156	no	no	no	no	no	no	DM-LS
Pyramidobacter	Resistin	Pyramidobacter+Pathways in cancer+LCA+stool+Resistin	Indirect	Genus	DM-associated hormones	0.45	0.156	no	no	no	no	no	no	DM-LS
Pyramidobacter	Resistin	Pyramidobacter+Glucagon signaling pathway+GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.45	0.156	no	no	no	no	no	no	DM-LS
Pyramidobacter	Resistin	Pyramidobacter+Small cell lung cancer-ACA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.45	0.156	no	no	no	no	no	no	DM-LS
Pyramidobacter	Resistin	Pyramidobacter+Pathways in cancer-Glycine+blood-Resistin	Indirect	Genus	DM-associated hormones	0.45	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella-Proteasome-IL-1ra+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella-Glycolysis / Gluconeogenesis-18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella+18:0-LPC+blood+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella-Carbon metabolism-18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella+Calcium signaling pathway+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella+Cushing syndrome+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella+Cocaine addiction+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella+Aldosterone synthesis and secretion+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella+GnRH signaling pathway+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella+Calcium signaling pathway+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella+Pancreatic secretion+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella+Long-term depression+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella+Amphetamine addiction+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella+Dopaminergic synapse+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella+18:0-LPC+blood+GPC+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella+Aldosterone synthesis and secretion+GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella+Adrenergic signaling in cardiomyocytes+GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
Prevotella	Resistin	Prevotella+Amphetamine addiction+GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	DM-LS
TCA+blood	Resistin	TCA+blood+FGF basic+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.339	0.156	no	no	no	no	no	no	DM-LS
iso-DCA+blood	Resistin	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.156	no	no	no	no	no	no	DM-LS
iso-DCA+blood	Resistin	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.156	no	no	no	no	no	no	DM-LS
iso-DCA+blood	Resistin	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.156	no	no	no	no	no	no	DM-LS
iso-DCA+blood	Resistin	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.156	no	no	no	no	no	no	DM-LS
iso-DCA+blood	Resistin	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.156	no	no	no	no	no	no	DM-LS
iso-DCA+blood	Resistin	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.156	no	no	no	no	no	no	DM-LS
HCA+stool	Resistin	HCA+stool-GPC+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.156	no	no	no	no	no	no	DM-LS
Roseburia	Resistin	Roseburia-16:0-LPC+blood+GPC+blood+Resistin	Indirect	Genus	DM-associated hormones	0.495	0.156	no	no	no	no	no	no	DM-LS
Roseburia	Resistin	Roseburia-20:1+blood-IL-1ra+Resistin	Indirect	Genus	DM-associated hormones	0.495	0.156	no	no	no	no	no	no	DM-LS
Roseburia	Resistin	Roseburia+CDCA+stool-LCA+stool+Resistin	Indirect	Genus	DM-associated hormones	0.495	0.156	no	no	no	no	no	no	DM-LS
Roseburia	Resistin	Roseburia+CA+stool-LCA+stool+Resistin	Indirect	Genus	DM-associated hormones	0.495	0.156	no	no	no	no	no	no	DM-LS
Roseburia	Resistin	Roseburia+CA+stool-18:0/20:4-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.495	0.156	no	no	no	no	no	no	DM-LS
Roseburia	Resistin	Roseburia+16:0/18:0-PS+blood+18:0/20:4-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.495	0.156	no	no	no	no	no	no	DM-LS
Roseburia	Resistin	Roseburia-16:0-LPC+blood+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.495	0.156	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Resistin	12-ketoDCA+stool+DCA+stool+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.156	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Resistin	12-ketoDCA+stool-Glycine+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.156	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Resistin	12-ketoDCA+stool+LCA+stool+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.156	no	no	no	no	no	no	DM-LS
GLCA+blood	Resistin	GLCA+blood-Sarcosine+blood-FGF basic+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.156	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	Resistin	L-Tryptophan+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.156	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	Resistin	L-Tryptophan+stool+18:0/22:6-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.156	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	Resistin	L-Tryptophan+stool+16:1/16:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.156	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	Resistin	L-Tryptophan+stool-18:3n6+blood+d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.156	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	Resistin	L-Tryptophan+stool+Phenylacetic acid+stool-IL-1ra+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.156	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	Resistin	L-Tryptophan+stool+20:3/18:0-PC+blood+ACA+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.156	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	Resistin	L-Tryptophan+stool+20:3/18:0-PC+blood+Glycine+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.156	no	no	no	no	no	no	DM-LS
CA+blood	Resistin	CA+blood-Cysteine+blood+Cystine+blood+Glycine+blood-Resistin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.156	no	no	no	no	no	no	DM-LS
CA+blood	Resistin	CA+blood+Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.156	no	no	no	no	no	no	DM-LS
CA+blood	Resistin	CA+blood+Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.156	no	no	no	no	no	no	DM-LS
CA+blood	Resistin	CA+blood-Cysteine+blood+L-2-Aminobutyric acid+blood-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.156	no	no	no	no	no	no	DM-LS
CA+blood	Resistin	CA+blood-Cysteine+blood-d18:1-14:0-SM+blood+d18:1-16:0-SM+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.156	no	no	no	no	no	no	DM-LS
CA+blood	Resistin	CA+blood+CDCA+blood+d18:1-14:1-SM+blood+d18:1-16:0-SM+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.156	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	Resistin	L-Phenylalanine+stool+20:3/18:0-PC+blood+Glycine+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.156	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	Resistin	L-Phenylalanine+stool+18:0/18:2-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.156	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	Resistin	L-Phenylalanine+stool+20:5/18:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.156	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	Resistin	L-Phenylalanine+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.156	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	Resistin	L-Phenylalanine+stool-18:3n6+blood+d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.156	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	Resistin	L-Phenylalanine+stool-18:0-LPE+blood+GPC+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.156	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	Resistin	L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.156	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	Resistin	L-Phenylalanine+stool+20:3/18:0-PC+blood+ACA+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.156	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	Resistin	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	serum_scfa	DM-associated hormones	0.407	0.156	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	Resistin	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	serum_scfa	DM-associated hormones	0.407	0.156	no	no	no	no	no	no	DM-LS
GCA+stool	Resistin	GCA+stool-Resistin	Direct	stool_bileacids	DM-associated hormones	0.0809	0.156	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	Resistin	T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.478	0.156	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	Resistin	T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.478	0.156	no	no	no	no	no	no	DM-LS
Coprococcus	Resistin	Coprococcus+DCA+stool+Resistin	Indirect	Genus	DM-associated hormones	0.612	0.156	no	no	no	no	no	no	DM-LS
Coprococcus	Resistin	Coprococcus-GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.612	0.156	no	no	no	no	no	no	DM-LS
Coprococcus	Resistin	Coprococcus+LCA+stool+Resistin	Indirect	Genus	DM-associated hormones	0.612	0.156	no	no	no	no	no	no	DM-LS
Coprococcus	Resistin	Coprococcus+18:0/20:4-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.612	0.156	no	no	no	no	no	no	DM-LS
Oscillospira	Resistin	Oscillospira+NOD-like receptor signaling pathway+AGE-RAGE signaling pathway in diabetic complications+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-LS
Oscillospira	Resistin	Oscillospira+NOD-like receptor signaling pathway+DCA+stool+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-LS
Oscillospira	Resistin	Oscillospira-4-hydroxybenzoic acid+stool+ACA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-LS
Oscillospira	Resistin	Oscillospira+Peroxisome-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-LS
Oscillospira	Resistin	Oscillospira-Adrenergic signaling in cardiomyocytes+GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-LS
Oscillospira	Resistin	Oscillospira-CDCA+stool-LCA+stool+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-LS
Oscillospira	Resistin	Oscillospira+NOD-like receptor signaling pathway+LCA+stool+Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	DM-LS
HCA+blood	Resistin	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.544	0.156	no	no	no	no	no	no	DM-LS
HCA+blood	Resistin	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.544	0.156	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Resistin	iso-LCA+stool+18:0/20:4-PI+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.156	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Resistin	iso-LCA+stool+LCA+stool+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.156	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Resistin	iso-LCA+stool-Glycine+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.156	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	Resistin	2-methyl-butyric acid m-C4+blood-CA+blood-Cysteine+blood+Cystine+blood+Glycine+blood-Resistin	Indirect	serum_scfa	DM-associated hormones	0.262	0.156	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	Resistin	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	serum_scfa	DM-associated hormones	0.262	0.156	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	Resistin	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	serum_scfa	DM-associated hormones	0.262	0.156	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	Resistin	2-methyl-butyric acid m-C4+blood-CA+blood-Cysteine+blood+L-2-Aminobutyric acid+blood-IL-1ra+Resistin	Indirect	serum_scfa	DM-associated hormones	0.262	0.156	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	Resistin	2-methyl-butyric acid m-C4+blood-CA+blood-Cysteine+blood-d18:1-14:0-SM+blood+d18:1-16:0-SM+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.262	0.156	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	Resistin	2-methyl-butyric acid m-C4+blood-CA+blood+CDCA+blood+d18:1-14:1-SM+blood+d18:1-16:0-SM+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.262	0.156	no	no	no	no	no	no	DM-LS
DCA+blood	Resistin	DCA+blood-MUFA%+blood-Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.156	no	no	no	no	no	no	DM-LS
DCA+blood	Resistin	DCA+blood-TCA+blood+FGF basic+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.156	no	no	no	no	no	no	DM-LS
DCA+blood	Resistin	DCA+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.156	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Resistin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.156	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Resistin	3-(3-Hydroxyphenyl)propanoic acid+stool+18:2/18:2-PS+blood+d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.156	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Resistin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.156	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Resistin	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood+d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.156	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Resistin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/20:5-PC+blood+IL-1ra+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.156	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Resistin	3-(3-Hydroxyphenyl)propanoic acid+stool-20:0/20:5-PC+blood+IL-1ra+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.156	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	Resistin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-IL-1ra+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.156	no	no	no	no	no	no	DM-LS
TCA+stool	Resistin	TCA+stool-18:0/20:4-PI+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	DM-LS
HDCA+stool	Resistin	HDCA+stool+LCA+stool+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.156	no	no	no	no	no	no	DM-LS
HDCA+stool	Resistin	HDCA+stool+18:0/20:4-PI+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.156	no	no	no	no	no	no	DM-LS
Lachnospira	Resistin	Lachnospira-Adherens junction+ACA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-LS
Lachnospira	Resistin	Lachnospira+8-HETE+blood-ACA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-LS
Lachnospira	Resistin	Lachnospira+18:0/20:5-PC+blood+IL-1ra+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-LS
Lachnospira	Resistin	Lachnospira+20:0/20:5-PC+blood+IL-1ra+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-LS
Lachnospira	Resistin	Lachnospira+18:1/18:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-LS
Lachnospira	Resistin	Lachnospira-d18:1-14:0-SM+blood+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-LS
Lachnospira	Resistin	Lachnospira+16:0/18:2-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-LS
Lachnospira	Resistin	Lachnospira+18:0/18:2-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-LS
Lachnospira	Resistin	Lachnospira-d18:0-24:1-SM+blood+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-LS
Lachnospira	Resistin	Lachnospira+18:1/16:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	DM-LS
Fusobacterium	Resistin	Fusobacterium-DCA+stool+Resistin	Indirect	Genus	DM-associated hormones	0.628	0.156	no	no	no	no	no	no	DM-LS
isobutyric acid C4+blood	Resistin	isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.156	up	up	no	no	no	no	DM-LS
isobutyric acid C4+blood	Resistin	isobutyric acid C4+blood+MUFA%+blood-Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.156	up	up	no	no	no	no	DM-LS
GCDCA+stool	Resistin	GCDCA+stool-Resistin	Direct	stool_bileacids	DM-associated hormones	0.0471	0.156	no	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Resistin	5-Hydroxytryptamine+stool-Propionic acid+stool-ACA+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.156	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Resistin	5-Hydroxytryptamine+stool-Propionic acid+stool-Glycine+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.156	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Resistin	5-Hydroxytryptamine+stool-Propionic acid+stool+18:0/20:4-PI+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.156	dn	dn	no	no	no	no	DM-LS
Odoribacter	Resistin	Odoribacter-d18:0-24:1-SM+blood+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.798	0.156	no	no	no	no	no	no	DM-LS
Odoribacter	Resistin	Odoribacter-L-2-Aminobutyric acid+blood-IL-1ra+Resistin	Indirect	Genus	DM-associated hormones	0.798	0.156	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Resistin	Isobutyric acid+stool+Phenylacetic acid+stool-IL-1ra+Resistin	Indirect	stool_scfa	DM-associated hormones	0.408	0.156	no	no	no	no	no	no	DM-LS
Lachnobacterium	Resistin	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	Genus	DM-associated hormones	0.867	0.156	no	no	no	no	no	no	DM-LS
Lachnobacterium	Resistin	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	Genus	DM-associated hormones	0.867	0.156	no	no	no	no	no	no	DM-LS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool+L-Tyrosine+stool-18:0-LPE+blood+GPC+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool+L-Tyrosine+stool-18:1/18:1-PE+blood-Glycine+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool-nutriCA+stool-Phenylacetic acid+stool-IL-1ra+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool+L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool-UDCA+stool-18:0/20:5-PC+blood+IL-1ra+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool-UDCA+stool-20:0/20:5-PC+blood+IL-1ra+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool-UDCA+stool+18:3n6+blood+d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool+L-Tyrosine+stool-18:3n6+blood+d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool-UDCA+stool-16:0/18:2-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool+L-Tyrosine+stool+18:1/18:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool+L-Tyrosine+stool+18:0/18:2-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool-UDCA+stool-16:0/22:6-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool+L-Tyrosine+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool-UDCA+stool-20:5/18:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Resistin	Kynurenic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	DM-LS
Anaerostipes	Resistin	Anaerostipes-Chronic myeloid leukemia-ACA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.568	0.156	no	no	no	no	no	no	DM-LS
Anaerostipes	Resistin	Anaerostipes-Insulin resistance+AGE-RAGE signaling pathway in diabetic complications+Resistin	Indirect	Genus	DM-associated hormones	0.568	0.156	no	no	no	no	no	no	DM-LS
Anaerostipes	Resistin	Anaerostipes-Hepatitis B+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.568	0.156	no	no	no	no	no	no	DM-LS
Anaerostipes	Resistin	Anaerostipes-Chronic myeloid leukemia+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.568	0.156	no	no	no	no	no	no	DM-LS
Anaerostipes	Resistin	Anaerostipes-Insulin resistance+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.568	0.156	no	no	no	no	no	no	DM-LS
Anaerostipes	Resistin	Anaerostipes-TNF signaling pathway+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.568	0.156	no	no	no	no	no	no	DM-LS
Anaerostipes	Resistin	Anaerostipes-Neurotrophin signaling pathway+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.568	0.156	no	no	no	no	no	no	DM-LS
Anaerostipes	Resistin	Anaerostipes-Prostate cancer+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.568	0.156	no	no	no	no	no	no	DM-LS
Anaerostipes	Resistin	Anaerostipes-Hepatitis B+GPC+blood+Resistin	Indirect	Genus	DM-associated hormones	0.568	0.156	no	no	no	no	no	no	DM-LS
TUDCA+stool	Resistin	TUDCA+stool-UDCA+stool+18:3n6+blood+d18:1-16:0-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.156	no	no	no	no	no	no	DM-LS
TUDCA+stool	Resistin	TUDCA+stool-UDCA+stool-16:0/22:6-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.156	no	no	no	no	no	no	DM-LS
TUDCA+stool	Resistin	TUDCA+stool-UDCA+stool-16:0/18:2-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.156	no	no	no	no	no	no	DM-LS
TUDCA+stool	Resistin	TUDCA+stool-UDCA+stool-20:5/18:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.156	no	no	no	no	no	no	DM-LS
TUDCA+stool	Resistin	TUDCA+stool-UDCA+stool-20:0/20:5-PC+blood+IL-1ra+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.156	no	no	no	no	no	no	DM-LS
TUDCA+stool	Resistin	TUDCA+stool-UDCA+stool-18:0/20:5-PC+blood+IL-1ra+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.156	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Resistin	Isovaleric acid+stool+Phenylacetic acid+stool-IL-1ra+Resistin	Indirect	stool_scfa	DM-associated hormones	0.343	0.156	no	no	no	no	no	no	DM-LS
Paraprevotella	Resistin	Paraprevotella+Arachidonic acid metabolism-18:0/20:4-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-LS
Paraprevotella	Resistin	Paraprevotella+Glutathione metabolism-AGE-RAGE signaling pathway in diabetic complications+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-LS
Paraprevotella	Resistin	Paraprevotella+Arachidonic acid metabolism-AGE-RAGE signaling pathway in diabetic complications+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-LS
Paraprevotella	Resistin	Paraprevotella+d18:1-20:0-SM+blood+GPC+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	DM-LS
iso-LCA+blood	Resistin	iso-LCA+blood-Sarcosine+blood-FGF basic+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.507	0.156	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	Resistin	Phenylacetic acid+stool-IL-1ra+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.156	no	no	no	no	no	no	DM-LS
Gemmiger	Resistin	Gemmiger-GCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.595	0.156	no	no	no	no	no	no	DM-LS
GDCA+stool	Resistin	GDCA+stool-Resistin	Direct	stool_bileacids	DM-associated hormones	0.656	0.156	no	no	no	no	no	no	DM-LS
Methanobrevibacter	Resistin	Methanobrevibacter+18:0-LPC+blood+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.629	0.156	no	no	no	no	no	no	DM-LS
Methanobrevibacter	Resistin	Methanobrevibacter+L-2-Aminobutyric acid+blood-IL-1ra+Resistin	Indirect	Genus	DM-associated hormones	0.629	0.156	no	no	no	no	no	no	DM-LS
Methanobrevibacter	Resistin	Methanobrevibacter+18:0-LPC+blood+GPC+blood+Resistin	Indirect	Genus	DM-associated hormones	0.629	0.156	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	Resistin	L-Tyrosine+stool-18:0-LPE+blood+GPC+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.156	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	Resistin	L-Tyrosine+stool-18:1/18:1-PE+blood-Glycine+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.156	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	Resistin	L-Tyrosine+stool+20:5/18:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.156	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	Resistin	L-Tyrosine+stool+18:0/18:2-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.156	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	Resistin	L-Tyrosine+stool+16:0/22:6-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.156	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	Resistin	L-Tyrosine+stool+18:1/18:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.156	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	Resistin	L-Tyrosine+stool-18:3n6+blood+d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.156	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	Resistin	L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.156	no	no	no	no	no	no	DM-LS
CDCA+stool	Resistin	CDCA+stool-LCA+stool+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.156	no	no	no	no	no	no	DM-LS
CA+stool	Resistin	CA+stool-LCA+stool+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.156	no	no	no	no	no	no	DM-LS
CA+stool	Resistin	CA+stool-18:0/20:4-PI+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.156	no	no	no	no	no	no	DM-LS
Slackia	Resistin	Slackia-Cystine+blood+Glycine+blood-Resistin	Indirect	Genus	DM-associated hormones	0.94	0.156	no	no	no	no	no	no	DM-LS
Slackia	Resistin	Slackia+Platinum drug resistance-ACA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.94	0.156	no	no	no	no	no	no	DM-LS
Slackia	Resistin	Slackia-16:1/16:1-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.94	0.156	no	no	no	no	no	no	DM-LS
Slackia	Resistin	Slackia+Platinum drug resistance+LCA+stool+Resistin	Indirect	Genus	DM-associated hormones	0.94	0.156	no	no	no	no	no	no	DM-LS
HDCA+blood	Resistin	HDCA+blood-Sarcosine+blood-FGF basic+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.156	no	no	no	no	no	no	DM-LS
UDCA+stool	Resistin	UDCA+stool+18:3n6+blood+d18:1-16:0-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-LS
UDCA+stool	Resistin	UDCA+stool-16:0/22:6-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-LS
UDCA+stool	Resistin	UDCA+stool-16:0/18:2-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-LS
UDCA+stool	Resistin	UDCA+stool-20:5/18:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-LS
UDCA+stool	Resistin	UDCA+stool-20:0/20:5-PC+blood+IL-1ra+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-LS
UDCA+stool	Resistin	UDCA+stool-18:0/20:5-PC+blood+IL-1ra+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	DM-LS
TDCA+stool	Resistin	TDCA+stool+UDCA+stool+18:3n6+blood+d18:1-16:0-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.156	no	no	no	no	no	no	DM-LS
TDCA+stool	Resistin	TDCA+stool+UDCA+stool-16:0/22:6-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.156	no	no	no	no	no	no	DM-LS
TDCA+stool	Resistin	TDCA+stool+UDCA+stool-16:0/18:2-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.156	no	no	no	no	no	no	DM-LS
TDCA+stool	Resistin	TDCA+stool+UDCA+stool-20:5/18:0-PC+blood-d18:1-16:0-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.156	no	no	no	no	no	no	DM-LS
TDCA+stool	Resistin	TDCA+stool+UDCA+stool-20:0/20:5-PC+blood+IL-1ra+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.156	no	no	no	no	no	no	DM-LS
TDCA+stool	Resistin	TDCA+stool+UDCA+stool-18:0/20:5-PC+blood+IL-1ra+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.156	no	no	no	no	no	no	DM-LS
nutriCA+stool	Resistin	nutriCA+stool-Phenylacetic acid+stool-IL-1ra+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.156	no	no	no	no	no	no	DM-LS
GDCA+blood	Resistin	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.156	no	no	no	no	no	no	DM-LS
GDCA+blood	Resistin	GDCA+blood+iso-LCA+blood-Sarcosine+blood-FGF basic+IL-17A-IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.156	no	no	no	no	no	no	DM-LS
GDCA+blood	Resistin	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.156	no	no	no	no	no	no	DM-LS
acetic acid C2+blood	Resistin	acetic acid C2+blood-d18:1-14:1-SM+blood+d18:1-16:0-SM+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.000193	0.156	up	dn	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	Resistin	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-1ra+Resistin	Indirect	serum_scfa	DM-associated hormones	0.117	0.156	no	no	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	Resistin	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-17A-IL-1ra+Resistin	Indirect	serum_scfa	DM-associated hormones	0.117	0.156	no	no	no	no	no	no	DM-LS
Adlercreutzia	Resistin	Adlercreutzia+18:0-LPC+blood+GPC+blood+Resistin	Indirect	Genus	DM-associated hormones	0.548	0.156	no	no	no	no	no	no	DM-LS
Adlercreutzia	Resistin	Adlercreutzia-14:0+blood-Glycine+blood-Resistin	Indirect	Genus	DM-associated hormones	0.548	0.156	no	no	no	no	no	no	DM-LS
Adlercreutzia	Resistin	Adlercreutzia-16:0/20:5-PC+blood+IL-1ra+Resistin	Indirect	Genus	DM-associated hormones	0.548	0.156	no	no	no	no	no	no	DM-LS
Adlercreutzia	Resistin	Adlercreutzia+18:0-LPC+blood+18:0/18:2-PI+blood+Resistin	Indirect	Genus	DM-associated hormones	0.548	0.156	no	no	no	no	no	no	DM-LS
Clostridium	Resistin	Clostridium-20:0/20:5-PC+blood+IL-1ra+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-LS
Clostridium	Resistin	Clostridium+20:4-LPC+blood+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Resistin	T-¦Á-MCA+stool-TCA+stool-18:0/20:4-PI+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.156	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	Resistin	12-ketoDCA+blood-8-HETE+blood-ACA+blood-Resistin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.156	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	Resistin	12-ketoDCA+blood-20:4-LPC+blood+d18:1-16:0-SM+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.156	no	no	no	no	no	no	DM-LS
Butyricicoccus	Resistin	Butyricicoccus+DCA+stool+Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	DM-LS
Blautia	Insulin	Blautia-16:0/22:6-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	DM-LS
Blautia	Insulin	Blautia-16:0/18:2-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	DM-LS
Blautia	Insulin	Blautia+d18:0-24:1-SM+blood-DMG+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	DM-LS
Blautia	Insulin	Blautia-18:1/16:0-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	DM-LS
Blautia	Insulin	Blautia+d18:1-16:1-SM+blood-L-Isoleucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	DM-LS
Blautia	Insulin	Blautia-16:0/18:2-PC+blood+16:0/20:3-PC+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	DM-LS
Blautia	Insulin	Blautia-16:0/18:2-PC+blood+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	DM-LS
Blautia	Insulin	Blautia-18:1/16:0-PC+blood+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	DM-LS
Blautia	Insulin	Blautia-L-Ornithine+blood+Valine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	DM-LS
Blautia	Insulin	Blautia-12-ketoDCA+stool+HDCA+stool-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	DM-LS
Blautia	Insulin	Blautia-12-ketoDCA+stool+LCA+stool-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	DM-LS
Parabacteroides	Insulin	Parabacteroides+Valine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	DM-LS
Parabacteroides	Insulin	Parabacteroides-15-HETE+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	DM-LS
Parabacteroides	Insulin	Parabacteroides+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	DM-LS
Parabacteroides	Insulin	Parabacteroides+L-Leucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	DM-LS
Parabacteroides	Insulin	Parabacteroides+L-Isoleucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	DM-LS
Parabacteroides	Insulin	Parabacteroides+Choline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	DM-LS
Dorea	Insulin	Dorea-18:0/22:6-PE+blood-18:2-LPA+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.00362	0.00058	up	no	dn	up	up	no	DM-LS
Faecalibacterium	Insulin	Faecalibacterium-L-Tryptophan+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	DM-LS
Faecalibacterium	Insulin	Faecalibacterium-Cysteine+blood+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	DM-LS
Faecalibacterium	Insulin	Faecalibacterium+d18:1-24:1-SM+blood-L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	DM-LS
Faecalibacterium	Insulin	Faecalibacterium-Cysteine+blood+L-Leucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	DM-LS
Faecalibacterium	Insulin	Faecalibacterium-Cysteine+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	DM-LS
Faecalibacterium	Insulin	Faecalibacterium-Cysteine+blood+Valine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	DM-LS
Faecalibacterium	Insulin	Faecalibacterium-16:0/18:1-PC+blood+16:0/20:3-PC+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	DM-LS
Faecalibacterium	Insulin	Faecalibacterium-16:0/18:2-PC+blood+16:0/20:3-PC+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	DM-LS
Faecalibacterium	Insulin	Faecalibacterium-16:1/16:1-PC+blood-18:0-LPA+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	DM-LS
Faecalibacterium	Insulin	Faecalibacterium-Phenylacetic acid+stool-18:0-LPA+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	DM-LS
Faecalibacterium	Insulin	Faecalibacterium-L-Tryptophan+stool-18:0-LPA+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	DM-LS
Faecalibacterium	Insulin	Faecalibacterium-16:1/16:1-PC+blood-20:1-LPA+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	DM-LS
Faecalibacterium	Insulin	Faecalibacterium-16:0/18:2-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	DM-LS
Faecalibacterium	Insulin	Faecalibacterium-16:0/18:1-PC+blood+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	DM-LS
Faecalibacterium	Insulin	Faecalibacterium-16:0/18:2-PC+blood+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	DM-LS
TUDCA+blood	Insulin	TUDCA+blood+Eotaxin+IL-4-IL-8-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.00058	no	no	dn	up	up	no	DM-LS
TUDCA+blood	Insulin	TUDCA+blood+Eotaxin-GM-CSF+IL-8-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.00058	no	no	dn	up	up	no	DM-LS
TUDCA+blood	Insulin	TUDCA+blood+Eotaxin+IL-17A-IL-8-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.00058	no	no	dn	up	up	no	DM-LS
isocapric acid iso-C6+blood	Insulin	isocapric acid iso-C6+blood-n3+blood+Taurine+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.00058	no	no	dn	up	up	no	DM-LS
Bacteroides	Insulin	Bacteroides+22:6n3+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.000267	0.00058	dn	dn	up	up	up	no	DM-LS
Propionic acid+stool	Insulin	Propionic acid+stool-18:2-LPA+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.00058	dn	no	up	up	up	no	DM-LS
[Ruminococcus]	Insulin	[Ruminococcus]-15-HETE+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0679	0.00058	no	no	dn	up	up	no	DM-LS
GUDCA+blood	Insulin	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-17A-IL-8-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.00058	no	no	dn	up	up	no	DM-LS
GUDCA+blood	Insulin	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-8-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.00058	no	no	dn	up	up	no	DM-LS
GUDCA+blood	Insulin	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-4-IL-8-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.00058	no	no	dn	up	up	no	DM-LS
Acetic acid+stool	Insulin	Acetic acid+stool-Cysteine+blood+Valine+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.00058	dn	no	no	up	up	no	DM-LS
Acetic acid+stool	Insulin	Acetic acid+stool-Cysteine+blood+L-Leucine+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.00058	dn	no	no	up	up	no	DM-LS
Acetic acid+stool	Insulin	Acetic acid+stool+Propionic acid+stool-18:2-LPA+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.00058	dn	no	no	up	up	no	DM-LS
Acetic acid+stool	Insulin	Acetic acid+stool-Cysteine+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.00058	dn	no	no	up	up	no	DM-LS
Acetic acid+stool	Insulin	Acetic acid+stool+AA+blood+Choline+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.00058	dn	no	no	up	up	no	DM-LS
Acetic acid+stool	Insulin	Acetic acid+stool-Cysteine+blood+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.00058	dn	no	no	up	up	no	DM-LS
Acetic acid+stool	Insulin	Acetic acid+stool-Phenylacetic acid+stool-18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.00058	dn	no	no	up	up	no	DM-LS
Alistipes	Insulin	Alistipes-L-Arginine+blood+Valine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0114	0.00058	no	up	no	up	up	no	DM-LS
Alistipes	Insulin	Alistipes-L-Arginine+blood+L-Leucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0114	0.00058	no	up	no	up	up	no	DM-LS
Alistipes	Insulin	Alistipes+12-ketoDCA+stool+LCA+stool-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0114	0.00058	no	up	no	up	up	no	DM-LS
Alistipes	Insulin	Alistipes+12-ketoDCA+stool+HDCA+stool-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0114	0.00058	no	up	no	up	up	no	DM-LS
Butyricimonas	Insulin	Butyricimonas+L-Lysine+blood+Valine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-LS
Butyricimonas	Insulin	Butyricimonas+L-Histidine+blood+Valine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-LS
Butyricimonas	Insulin	Butyricimonas+L-Lysine+blood+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-LS
Butyricimonas	Insulin	Butyricimonas+L-Histidine+blood+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-LS
Butyricimonas	Insulin	Butyricimonas-d18:1-24:1-SM+blood-L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-LS
Butyricimonas	Insulin	Butyricimonas-Prion disease+18:0-LPA+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-LS
Butyricimonas	Insulin	Butyricimonas-Cardiac muscle contraction+18:0-LPA+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-LS
Butyricimonas	Insulin	Butyricimonas+L-Histidine+blood+L-Leucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-LS
Butyricimonas	Insulin	Butyricimonas+L-Histidine+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-LS
Butyricimonas	Insulin	Butyricimonas-d18:0-24:1-SM+blood-DMG+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-LS
Butyricimonas	Insulin	Butyricimonas-d18:1-14:0-SM+blood-DMG+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	DM-LS
Collinsella	Insulin	Collinsella-HDCA+stool-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.128	0.00058	no	no	no	up	up	no	DM-LS
Collinsella	Insulin	Collinsella+20:1-LPA+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.128	0.00058	no	no	no	up	up	no	DM-LS
Collinsella	Insulin	Collinsella-LCA+stool-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.128	0.00058	no	no	no	up	up	no	DM-LS
total_blood_scfa+blood	Insulin	total_blood_scfa+blood+TUDCA+blood+Eotaxin+IL-4-IL-8-C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.168	0.00058	no	no	no	up	up	no	DM-LS
total_blood_scfa+blood	Insulin	total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-8-C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.168	0.00058	no	no	no	up	up	no	DM-LS
total_blood_scfa+blood	Insulin	total_blood_scfa+blood+TUDCA+blood+Eotaxin+IL-17A-IL-8-C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.168	0.00058	no	no	no	up	up	no	DM-LS
[Eubacterium]	Insulin	[Eubacterium]-Viral myocarditis-L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0692	0.00058	no	no	no	up	up	no	DM-LS
[Eubacterium]	Insulin	[Eubacterium]-Salmonella infection-L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0692	0.00058	no	no	no	up	up	no	DM-LS
[Eubacterium]	Insulin	[Eubacterium]-Viral myocarditis-Valine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0692	0.00058	no	no	no	up	up	no	DM-LS
LCA+stool	Insulin	LCA+stool-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.00058	no	no	no	up	up	no	DM-LS
Akkermansia	Insulin	Akkermansia+LCA+stool-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.23	0.00058	no	no	no	up	up	no	DM-LS
Bifidobacterium	Insulin	Bifidobacterium-18:2/20:4-PC+blood+20:3/16:0-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.105	0.00058	no	dn	no	up	up	no	DM-LS
Bifidobacterium	Insulin	Bifidobacterium+Glycine+blood+L-Glutamine+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.105	0.00058	no	dn	no	up	up	no	DM-LS
Bifidobacterium	Insulin	Bifidobacterium+Chemical carcinogenesis - receptor activation-L-Glutamine+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.105	0.00058	no	dn	no	up	up	no	DM-LS
Bifidobacterium	Insulin	Bifidobacterium+Glycine+blood+L-Asparagine+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.105	0.00058	no	dn	no	up	up	no	DM-LS
Bifidobacterium	Insulin	Bifidobacterium-FGF basic+IL-17A-IL-8-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.105	0.00058	no	dn	no	up	up	no	DM-LS
Bifidobacterium	Insulin	Bifidobacterium+Glycine+blood+L-Arginine+blood+L-Leucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.105	0.00058	no	dn	no	up	up	no	DM-LS
Bifidobacterium	Insulin	Bifidobacterium+Chemical carcinogenesis - receptor activation+16:0/16:0-PC+blood-18:0-LPA+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.105	0.00058	no	dn	no	up	up	no	DM-LS
Bifidobacterium	Insulin	Bifidobacterium+Glycine+blood+L-Arginine+blood+Valine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.105	0.00058	no	dn	no	up	up	no	DM-LS
Bifidobacterium	Insulin	Bifidobacterium+d18:1-18:1-SM+blood-L-Ornithine+blood+Valine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.105	0.00058	no	dn	no	up	up	no	DM-LS
Bifidobacterium	Insulin	Bifidobacterium+Glycine+blood+SFA%+blood+Valine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.105	0.00058	no	dn	no	up	up	no	DM-LS
Ruminococcus	Insulin	Ruminococcus+Cell adhesion molecules-Valine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.335	0.00058	no	no	no	up	up	no	DM-LS
Ruminococcus	Insulin	Ruminococcus+Cell adhesion molecules-L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.335	0.00058	no	no	no	up	up	no	DM-LS
Ruminococcus	Insulin	Ruminococcus+22:6n3+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.335	0.00058	no	no	no	up	up	no	DM-LS
GCDCA+blood	Insulin	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4-IL-8-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.00058	no	no	no	up	up	no	DM-LS
GCDCA+blood	Insulin	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-8-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.00058	no	no	no	up	up	no	DM-LS
GCDCA+blood	Insulin	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-8-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.00058	no	no	no	up	up	no	DM-LS
Succinivibrio	Insulin	Succinivibrio-L-Tyrosine+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.138	0.00058	no	no	no	up	up	no	DM-LS
Succinivibrio	Insulin	Succinivibrio-L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.138	0.00058	no	no	no	up	up	no	DM-LS
ACA+blood	Insulin	ACA+blood-DL-methionine sulfoxide+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.00058	no	no	no	up	up	no	DM-LS
ACA+blood	Insulin	ACA+blood-DL-methionine sulfoxide+blood+L-Tyrosine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.00058	no	no	no	up	up	no	DM-LS
DCA+stool	Insulin	DCA+stool-16:0/20:3-PC+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.00058	no	no	no	up	up	no	DM-LS
DCA+stool	Insulin	DCA+stool-18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.00058	no	no	no	up	up	no	DM-LS
DCA+stool	Insulin	DCA+stool+HDCA+stool-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.00058	no	no	no	up	up	no	DM-LS
DCA+stool	Insulin	DCA+stool-18:2-LPA+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.00058	no	no	no	up	up	no	DM-LS
DCA+stool	Insulin	DCA+stool+LCA+stool-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.00058	no	no	no	up	up	no	DM-LS
Butyric acid+stool	Insulin	Butyric acid+stool-16:1/16:1-PC+blood-20:1-LPA+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.102	0.00058	dn	no	no	up	up	no	DM-LS
Butyric acid+stool	Insulin	Butyric acid+stool+AA+blood+Choline+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.102	0.00058	dn	no	no	up	up	no	DM-LS
Butyric acid+stool	Insulin	Butyric acid+stool-Phenylacetic acid+stool-18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.102	0.00058	dn	no	no	up	up	no	DM-LS
Butyric acid+stool	Insulin	Butyric acid+stool-16:1/16:1-PC+blood-18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.102	0.00058	dn	no	no	up	up	no	DM-LS
Butyric acid+stool	Insulin	Butyric acid+stool+Propionic acid+stool-18:2-LPA+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.102	0.00058	dn	no	no	up	up	no	DM-LS
4-hydroxybenzoic acid+stool	Insulin	4-hydroxybenzoic acid+stool-HDCA+stool-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.00058	no	dn	no	up	up	no	DM-LS
GCA+blood	Insulin	GCA+blood+FGF basic+IL-17A-IL-8-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.00058	no	no	no	up	up	no	DM-LS
ACA+stool	Insulin	ACA+stool-L-Citrulline+blood+L-Leucine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.00058	no	no	no	up	up	no	DM-LS
ACA+stool	Insulin	ACA+stool-L-Citrulline+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.00058	no	no	no	up	up	no	DM-LS
ACA+stool	Insulin	ACA+stool-L-Citrulline+blood+Valine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.00058	no	no	no	up	up	no	DM-LS
ACA+stool	Insulin	ACA+stool+16:0-LPC+blood+18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.00058	no	no	no	up	up	no	DM-LS
CDCA+blood	Insulin	CDCA+blood-Cysteine+blood+L-Leucine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.00058	no	no	no	up	up	no	DM-LS
CDCA+blood	Insulin	CDCA+blood+d18:1-14:1-SM+blood-DMG+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.00058	no	no	no	up	up	no	DM-LS
CDCA+blood	Insulin	CDCA+blood-Cysteine+blood+L-Tyrosine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.00058	no	no	no	up	up	no	DM-LS
CDCA+blood	Insulin	CDCA+blood-L-Tryptophan+blood+L-Tyrosine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.00058	no	no	no	up	up	no	DM-LS
CDCA+blood	Insulin	CDCA+blood-L-Methionine+blood+L-Tyrosine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.00058	no	no	no	up	up	no	DM-LS
CDCA+blood	Insulin	CDCA+blood-Cysteine+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.00058	no	no	no	up	up	no	DM-LS
CDCA+blood	Insulin	CDCA+blood-L-Tryptophan+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.00058	no	no	no	up	up	no	DM-LS
CDCA+blood	Insulin	CDCA+blood-L-Methionine+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.00058	no	no	no	up	up	no	DM-LS
CDCA+blood	Insulin	CDCA+blood+d18:1-14:1-SM+blood-L-Isoleucine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.00058	no	no	no	up	up	no	DM-LS
CDCA+blood	Insulin	CDCA+blood-Cysteine+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.00058	no	no	no	up	up	no	DM-LS
capric acid C6+blood	Insulin	capric acid C6+blood+L-Glutamine+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.433	0.00058	no	no	no	up	up	no	DM-LS
capric acid C6+blood	Insulin	capric acid C6+blood-d18:1-16:1-SM+blood-L-Isoleucine+blood+C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.433	0.00058	no	no	no	up	up	no	DM-LS
capric acid C6+blood	Insulin	capric acid C6+blood+L-Asparagine+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.433	0.00058	no	no	no	up	up	no	DM-LS
capric acid C6+blood	Insulin	capric acid C6+blood+L-Tryptophan+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.433	0.00058	no	no	no	up	up	no	DM-LS
capric acid C6+blood	Insulin	capric acid C6+blood+octanoic acid C8+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.433	0.00058	no	no	no	up	up	no	DM-LS
capric acid C6+blood	Insulin	capric acid C6+blood+L-Tryptophan+blood+L-Tyrosine+blood+C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.433	0.00058	no	no	no	up	up	no	DM-LS
Pyramidobacter	Insulin	"Pyramidobacter+Parathyroid hormone synthesis, secretion and action-C-peptide+Insulin"	Indirect	Genus	DM-associated hormones	0.45	0.00058	no	no	no	up	up	no	DM-LS
Pyramidobacter	Insulin	Pyramidobacter+HDCA+stool-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.45	0.00058	no	no	no	up	up	no	DM-LS
Prevotella	Insulin	Prevotella+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	DM-LS
Prevotella	Insulin	Prevotella+L-Leucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	DM-LS
TCA+blood	Insulin	TCA+blood+FGF basic+IL-17A-IL-8-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.339	0.00058	no	no	no	up	up	no	DM-LS
iso-DCA+blood	Insulin	iso-DCA+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.00058	no	no	no	up	up	no	DM-LS
iso-DCA+blood	Insulin	iso-DCA+blood+L-Leucine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.00058	no	no	no	up	up	no	DM-LS
HCA+stool	Insulin	HCA+stool+18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.00058	no	no	no	up	up	no	DM-LS
Roseburia	Insulin	Roseburia-Valine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.495	0.00058	no	no	no	up	up	no	DM-LS
12-ketoDCA+stool	Insulin	12-ketoDCA+stool+HDCA+stool-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.00058	no	no	no	up	up	no	DM-LS
12-ketoDCA+stool	Insulin	12-ketoDCA+stool+LCA+stool-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.00058	no	no	no	up	up	no	DM-LS
GLCA+blood	Insulin	GLCA+blood-PUFA/MUFA+blood+TXB2+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.00058	no	no	no	up	up	no	DM-LS
GLCA+blood	Insulin	GLCA+blood-PUFA/MUFA+blood+SFA%+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.00058	no	no	no	up	up	no	DM-LS
GLCA+blood	Insulin	GLCA+blood+HDCA+blood+L-Ornithine+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.00058	no	no	no	up	up	no	DM-LS
GLCA+blood	Insulin	GLCA+blood+iso-LCA+blood+L-Ornithine+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.00058	no	no	no	up	up	no	DM-LS
L-Tryptophan+stool	Insulin	L-Tryptophan+stool-18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.00058	no	no	no	up	up	no	DM-LS
L-Tryptophan+stool	Insulin	L-Tryptophan+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.00058	no	no	no	up	up	no	DM-LS
CA+blood	Insulin	CA+blood-Cysteine+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.00058	no	no	no	up	up	no	DM-LS
CA+blood	Insulin	CA+blood-Cysteine+blood+L-Tyrosine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.00058	no	no	no	up	up	no	DM-LS
CA+blood	Insulin	CA+blood-Cysteine+blood+L-Leucine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.00058	no	no	no	up	up	no	DM-LS
CA+blood	Insulin	CA+blood-Cysteine+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.00058	no	no	no	up	up	no	DM-LS
CA+blood	Insulin	CA+blood-L-Glutamine+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.00058	no	no	no	up	up	no	DM-LS
L-Phenylalanine+stool	Insulin	L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.00058	no	no	no	up	up	no	DM-LS
butyric acid C4+blood	Insulin	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood+SFA%+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.407	0.00058	no	no	no	up	up	no	DM-LS
GCA+stool	Insulin	GCA+stool+GDCA+stool-L-Isoleucine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.00058	no	no	no	up	up	no	DM-LS
GCA+stool	Insulin	GCA+stool+GCDCA+stool-L-Isoleucine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.00058	no	no	no	up	up	no	DM-LS
GCA+stool	Insulin	GCA+stool+16:0/18:1-PC+blood+16:0/20:3-PC+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.00058	no	no	no	up	up	no	DM-LS
GCA+stool	Insulin	GCA+stool+TCA+stool+16:0/20:3-PC+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.00058	no	no	no	up	up	no	DM-LS
GCA+stool	Insulin	GCA+stool-TXB2+blood+Valine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.00058	no	no	no	up	up	no	DM-LS
GCA+stool	Insulin	GCA+stool+16:0/18:1-PC+blood+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.00058	no	no	no	up	up	no	DM-LS
GCA+stool	Insulin	GCA+stool+18:0/16:0-PC+blood+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.00058	no	no	no	up	up	no	DM-LS
GCA+stool	Insulin	GCA+stool+TCA+stool+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.00058	no	no	no	up	up	no	DM-LS
T-a-MCA+blood	Insulin	T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-8-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.478	0.00058	no	no	no	up	up	no	DM-LS
T-a-MCA+blood	Insulin	T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4-IL-8-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.478	0.00058	no	no	no	up	up	no	DM-LS
T-a-MCA+blood	Insulin	T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-8-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.478	0.00058	no	no	no	up	up	no	DM-LS
Coprococcus	Insulin	Coprococcus+LCA+stool-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	DM-LS
Oscillospira	Insulin	Oscillospira+Valine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	DM-LS
HCA+blood	Insulin	HCA+blood-MUFA+blood-PUFA/MUFA+blood+TXB2+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.544	0.00058	no	no	no	up	up	no	DM-LS
HCA+blood	Insulin	HCA+blood-MUFA+blood-PUFA/MUFA+blood+SFA%+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.544	0.00058	no	no	no	up	up	no	DM-LS
HCA+blood	Insulin	HCA+blood-MUFA+blood+MUFA%+blood+SFA%+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.544	0.00058	no	no	no	up	up	no	DM-LS
iso-LCA+stool	Insulin	iso-LCA+stool+LCA+stool-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.00058	no	no	no	up	up	no	DM-LS
2-methyl-butyric acid m-C4+blood	Insulin	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+L-Leucine+blood+C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.262	0.00058	no	no	no	up	up	no	DM-LS
2-methyl-butyric acid m-C4+blood	Insulin	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.262	0.00058	no	no	no	up	up	no	DM-LS
2-methyl-butyric acid m-C4+blood	Insulin	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.262	0.00058	no	no	no	up	up	no	DM-LS
DCA+blood	Insulin	DCA+blood-L-Glutamine+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.00058	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Insulin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.00058	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Insulin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.00058	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Insulin	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood-DMG+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.00058	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Insulin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2/16:0-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.00058	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Insulin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.00058	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Insulin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.00058	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Insulin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2n6c+blood-20:1-LPA+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.00058	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Insulin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:3/18:2-PC+blood-L-Isoleucine+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.00058	no	no	no	up	up	no	DM-LS
Indole-3-Acetic acid+stool	Insulin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.00058	no	no	no	up	up	no	DM-LS
Indole-3-Acetic acid+stool	Insulin	Indole-3-Acetic acid+stool+L-Tryptophan+stool-18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.00058	no	no	no	up	up	no	DM-LS
Indole-3-Acetic acid+stool	Insulin	Indole-3-Acetic acid+stool+L-Tryptophan+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.00058	no	no	no	up	up	no	DM-LS
Indole-3-Acetic acid+stool	Insulin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.00058	no	no	no	up	up	no	DM-LS
Indole-3-Acetic acid+stool	Insulin	Indole-3-Acetic acid+stool+L-Tyrosine+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.00058	no	no	no	up	up	no	DM-LS
TCA+stool	Insulin	TCA+stool+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.00058	no	no	no	up	up	no	DM-LS
TCA+stool	Insulin	TCA+stool+16:0/20:3-PC+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.00058	no	no	no	up	up	no	DM-LS
HDCA+stool	Insulin	HDCA+stool-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.00058	no	no	no	up	up	no	DM-LS
Lachnospira	Insulin	Lachnospira+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-LS
Lachnospira	Insulin	Lachnospira+Choline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-LS
Lachnospira	Insulin	Lachnospira+16:0/20:3-PC+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	DM-LS
Fusobacterium	Insulin	Fusobacterium+16:0/20:3-PC+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.628	0.00058	no	no	no	up	up	no	DM-LS
Fusobacterium	Insulin	Fusobacterium+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.628	0.00058	no	no	no	up	up	no	DM-LS
isobutyric acid C4+blood	Insulin	isobutyric acid C4+blood+MUFA%+blood+SFA%+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.00058	up	up	no	up	up	no	DM-LS
GCDCA+stool	Insulin	GCDCA+stool-L-Isoleucine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.00058	no	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	Insulin	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.00058	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	Insulin	5-Hydroxytryptamine+stool+L-Tyrosine+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.00058	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	Insulin	5-Hydroxytryptamine+stool-Propionic acid+stool-18:2-LPA+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.00058	dn	dn	no	up	up	no	DM-LS
Odoribacter	Insulin	Odoribacter+IL-8-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-LS
Odoribacter	Insulin	Odoribacter+Choline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	Insulin	Isobutyric acid+stool+L-Tryptophan+stool-18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.408	0.00058	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	Insulin	Isobutyric acid+stool+Phenylacetic acid+stool-18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.408	0.00058	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	Insulin	Isobutyric acid+stool+L-Tyrosine+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.408	0.00058	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	Insulin	Isobutyric acid+stool+L-Tryptophan+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.408	0.00058	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	Insulin	Isobutyric acid+stool+L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.408	0.00058	no	no	no	up	up	no	DM-LS
Lachnobacterium	Insulin	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-8-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.867	0.00058	no	no	no	up	up	no	DM-LS
Lachnobacterium	Insulin	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4-IL-8-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.867	0.00058	no	no	no	up	up	no	DM-LS
Lachnobacterium	Insulin	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-8-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.867	0.00058	no	no	no	up	up	no	DM-LS
Kynurenic acid+stool	Insulin	Kynurenic acid+stool+L-Tyrosine+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.00058	dn	dn	no	up	up	no	DM-LS
Anaerostipes	Insulin	Anaerostipes+15-HETE+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.568	0.00058	no	no	no	up	up	no	DM-LS
Anaerostipes	Insulin	Anaerostipes-L-Isoleucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.568	0.00058	no	no	no	up	up	no	DM-LS
TUDCA+stool	Insulin	TUDCA+stool-UDCA+stool-16:0/16:0-PC+blood-18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.00058	no	no	no	up	up	no	DM-LS
TUDCA+stool	Insulin	TUDCA+stool-UDCA+stool-18:2/16:0-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.00058	no	no	no	up	up	no	DM-LS
TUDCA+stool	Insulin	TUDCA+stool-UDCA+stool-16:0/22:6-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.00058	no	no	no	up	up	no	DM-LS
TUDCA+stool	Insulin	TUDCA+stool-UDCA+stool-16:0/18:2-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.00058	no	no	no	up	up	no	DM-LS
TUDCA+stool	Insulin	TUDCA+stool-UDCA+stool-16:0/18:2-PC+blood+16:0/20:3-PC+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.00058	no	no	no	up	up	no	DM-LS
TUDCA+stool	Insulin	TUDCA+stool-UDCA+stool-16:0/18:2-PC+blood+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.00058	no	no	no	up	up	no	DM-LS
TUDCA+stool	Insulin	TUDCA+stool-UDCA+stool-18:2n6c+blood-20:1-LPA+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.00058	no	no	no	up	up	no	DM-LS
TUDCA+stool	Insulin	TUDCA+stool-UDCA+stool-18:3n3+blood-20:1-LPA+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.00058	no	no	no	up	up	no	DM-LS
TUDCA+stool	Insulin	TUDCA+stool-UDCA+stool+d18:1-16:1-SM+blood-L-Isoleucine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.00058	no	no	no	up	up	no	DM-LS
TUDCA+stool	Insulin	TUDCA+stool-UDCA+stool-L-Ornithine+blood+Valine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.00058	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	Insulin	Isovaleric acid+stool+L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.343	0.00058	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	Insulin	Isovaleric acid+stool+L-Tyrosine+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.343	0.00058	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	Insulin	Isovaleric acid+stool+L-Tryptophan+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.343	0.00058	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	Insulin	Isovaleric acid+stool+Phenylacetic acid+stool-18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.343	0.00058	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	Insulin	Isovaleric acid+stool+L-Tryptophan+stool-18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.343	0.00058	no	no	no	up	up	no	DM-LS
Paraprevotella	Insulin	Paraprevotella+Betaine+blood+Valine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.118	0.00058	no	no	no	up	up	no	DM-LS
Paraprevotella	Insulin	Paraprevotella+Arachidonic acid metabolism-HDCA+stool-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.118	0.00058	no	no	no	up	up	no	DM-LS
Paraprevotella	Insulin	Paraprevotella+Arachidonic acid metabolism+Choline+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.118	0.00058	no	no	no	up	up	no	DM-LS
Paraprevotella	Insulin	Paraprevotella+Betaine+blood+L-Isoleucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.118	0.00058	no	no	no	up	up	no	DM-LS
iso-LCA+blood	Insulin	iso-LCA+blood+L-Ornithine+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.507	0.00058	no	no	no	up	up	no	DM-LS
Phenylacetic acid+stool	Insulin	Phenylacetic acid+stool-18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.00058	no	no	no	up	up	no	DM-LS
Gemmiger	Insulin	Gemmiger+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.595	0.00058	no	no	no	up	up	no	DM-LS
GDCA+stool	Insulin	GDCA+stool-L-Isoleucine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.00058	no	no	no	up	up	no	DM-LS
Methanobrevibacter	Insulin	Methanobrevibacter+Valine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.629	0.00058	no	no	no	up	up	no	DM-LS
Methanobrevibacter	Insulin	Methanobrevibacter+L-Leucine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.629	0.00058	no	no	no	up	up	no	DM-LS
L-Tyrosine+stool	Insulin	L-Tyrosine+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.00058	no	no	no	up	up	no	DM-LS
CDCA+stool	Insulin	CDCA+stool-LCA+stool-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.00058	no	no	no	up	up	no	DM-LS
CDCA+stool	Insulin	CDCA+stool-HDCA+stool-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.00058	no	no	no	up	up	no	DM-LS
CDCA+stool	Insulin	CDCA+stool+18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.00058	no	no	no	up	up	no	DM-LS
CA+stool	Insulin	CA+stool-HDCA+stool-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.00058	no	no	no	up	up	no	DM-LS
CA+stool	Insulin	CA+stool-LCA+stool-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.00058	no	no	no	up	up	no	DM-LS
Slackia	Insulin	Slackia-15-HETE+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.94	0.00058	no	no	no	up	up	no	DM-LS
HDCA+blood	Insulin	HDCA+blood+L-Ornithine+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.00058	no	no	no	up	up	no	DM-LS
UDCA+stool	Insulin	UDCA+stool-16:0/16:0-PC+blood-18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.00058	no	no	no	up	up	no	DM-LS
UDCA+stool	Insulin	UDCA+stool-18:2/16:0-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.00058	no	no	no	up	up	no	DM-LS
UDCA+stool	Insulin	UDCA+stool-16:0/22:6-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.00058	no	no	no	up	up	no	DM-LS
UDCA+stool	Insulin	UDCA+stool-16:0/18:2-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.00058	no	no	no	up	up	no	DM-LS
UDCA+stool	Insulin	UDCA+stool-16:0/18:2-PC+blood+16:0/20:3-PC+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.00058	no	no	no	up	up	no	DM-LS
UDCA+stool	Insulin	UDCA+stool-16:0/18:2-PC+blood+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.00058	no	no	no	up	up	no	DM-LS
UDCA+stool	Insulin	UDCA+stool-18:2n6c+blood-20:1-LPA+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.00058	no	no	no	up	up	no	DM-LS
UDCA+stool	Insulin	UDCA+stool-18:3n3+blood-20:1-LPA+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.00058	no	no	no	up	up	no	DM-LS
UDCA+stool	Insulin	UDCA+stool+d18:1-16:1-SM+blood-L-Isoleucine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.00058	no	no	no	up	up	no	DM-LS
UDCA+stool	Insulin	UDCA+stool-L-Ornithine+blood+Valine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.00058	no	no	no	up	up	no	DM-LS
TDCA+stool	Insulin	TDCA+stool+UDCA+stool-16:0/16:0-PC+blood-18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-LS
TDCA+stool	Insulin	TDCA+stool+UDCA+stool-18:2/16:0-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-LS
TDCA+stool	Insulin	TDCA+stool+UDCA+stool-16:0/22:6-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-LS
TDCA+stool	Insulin	TDCA+stool+UDCA+stool-16:0/18:2-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-LS
TDCA+stool	Insulin	TDCA+stool+UDCA+stool-16:0/18:2-PC+blood+16:0/20:3-PC+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-LS
TDCA+stool	Insulin	TDCA+stool+UDCA+stool-16:0/18:2-PC+blood+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-LS
TDCA+stool	Insulin	TDCA+stool+UDCA+stool-18:2n6c+blood-20:1-LPA+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-LS
TDCA+stool	Insulin	TDCA+stool+UDCA+stool-18:3n3+blood-20:1-LPA+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-LS
TDCA+stool	Insulin	TDCA+stool+UDCA+stool+d18:1-16:1-SM+blood-L-Isoleucine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-LS
TDCA+stool	Insulin	TDCA+stool+UDCA+stool-L-Ornithine+blood+Valine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.00058	no	no	no	up	up	no	DM-LS
nutriCA+stool	Insulin	nutriCA+stool-18:2n6c+blood-20:1-LPA+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.00058	no	no	no	up	up	no	DM-LS
nutriCA+stool	Insulin	nutriCA+stool-18:3n3+blood-20:1-LPA+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.00058	no	no	no	up	up	no	DM-LS
nutriCA+stool	Insulin	nutriCA+stool-TXB2+blood+Valine+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.00058	no	no	no	up	up	no	DM-LS
nutriCA+stool	Insulin	nutriCA+stool-16:0/16:0-PC+blood-18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.00058	no	no	no	up	up	no	DM-LS
nutriCA+stool	Insulin	nutriCA+stool-Phenylacetic acid+stool-18:0-LPA+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.00058	no	no	no	up	up	no	DM-LS
GDCA+blood	Insulin	GDCA+blood+iso-LCA+blood+L-Ornithine+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.00058	no	no	no	up	up	no	DM-LS
acetic acid C2+blood	Insulin	acetic acid C2+blood-d18:1-14:1-SM+blood-L-Isoleucine+blood+C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.000193	0.00058	up	dn	no	up	up	no	DM-LS
acetic acid C2+blood	Insulin	acetic acid C2+blood-d18:1-14:1-SM+blood-DMG+blood+C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.000193	0.00058	up	dn	no	up	up	no	DM-LS
isovaleric acid iso-C5+blood	Insulin	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-4-IL-8-C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.117	0.00058	no	no	no	up	up	no	DM-LS
isovaleric acid iso-C5+blood	Insulin	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-8-C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.117	0.00058	no	no	no	up	up	no	DM-LS
isovaleric acid iso-C5+blood	Insulin	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-17A-IL-8-C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.117	0.00058	no	no	no	up	up	no	DM-LS
Adlercreutzia	Insulin	Adlercreutzia+18:1-LPC+blood-L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.548	0.00058	no	no	no	up	up	no	DM-LS
Adlercreutzia	Insulin	Adlercreutzia-16:0/20:5-PC+blood-18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.548	0.00058	no	no	no	up	up	no	DM-LS
Clostridium	Insulin	Clostridium+20:1-LPA+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.925	0.00058	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	Insulin	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.00058	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	Insulin	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.00058	no	no	no	up	up	no	DM-LS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-20:3-LPE+blood+Choline+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-LS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-L-Lysine+blood+L-Tyrosine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-LS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-L-Lysine+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-LS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-L-Arginine+blood+Valine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-LS
12-ketoDCA+blood	Insulin	12-ketoDCA+blood-L-Arginine+blood+L-Leucine+blood+C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus-18:0/18:2-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus-18:2/16:0-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus-18:1/18:0-PC+blood+DMG+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus+DCA+stool+HDCA+stool-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus+DCA+stool+LCA+stool-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus-Phenylacetic acid+stool-18:0-LPA+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus-L-Tryptophan+stool-18:0-LPA+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus+Viral myocarditis-L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus-L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus+Cell adhesion molecules-L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus-L-Tryptophan+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus-L-Tyrosine+stool+L-Tyrosine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus+Viral myocarditis-Valine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus+Cell adhesion molecules-Valine+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus+DCA+stool-16:0/20:3-PC+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus+DCA+stool-18:2-LPA+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus-18:0/18:2-PC+blood+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus+DCA+stool-18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Butyricicoccus	Insulin	Butyricicoccus-18:1/18:0-PC+blood+18:1/18:1-PC+blood+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	DM-LS
Blautia	C-peptide	Blautia-16:0/22:6-PC+blood+DMG+blood+C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	DM-LS
Blautia	C-peptide	Blautia-16:0/18:2-PC+blood+DMG+blood+C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	DM-LS
Blautia	C-peptide	Blautia+d18:0-24:1-SM+blood-DMG+blood+C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	DM-LS
Blautia	C-peptide	Blautia-18:1/16:0-PC+blood+DMG+blood+C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	DM-LS
Blautia	C-peptide	Blautia+d18:1-16:1-SM+blood-L-Isoleucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	DM-LS
Blautia	C-peptide	Blautia-16:0/18:2-PC+blood+16:0/20:3-PC+blood+C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	DM-LS
Blautia	C-peptide	Blautia-16:0/18:2-PC+blood+18:1/18:1-PC+blood+C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	DM-LS
Blautia	C-peptide	Blautia-18:1/16:0-PC+blood+18:1/18:1-PC+blood+C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	DM-LS
Blautia	C-peptide	Blautia-L-Ornithine+blood+Valine+blood+C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	DM-LS
Blautia	C-peptide	Blautia-12-ketoDCA+stool+HDCA+stool-C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	DM-LS
Blautia	C-peptide	Blautia-12-ketoDCA+stool+LCA+stool-C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	DM-LS
Parabacteroides	C-peptide	Parabacteroides+Valine+blood+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	DM-LS
Parabacteroides	C-peptide	Parabacteroides-15-HETE+blood-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	DM-LS
Parabacteroides	C-peptide	Parabacteroides+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	DM-LS
Parabacteroides	C-peptide	Parabacteroides+L-Leucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	DM-LS
Parabacteroides	C-peptide	Parabacteroides+L-Isoleucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	DM-LS
Parabacteroides	C-peptide	Parabacteroides+Choline+blood+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	DM-LS
Dorea	C-peptide	Dorea-18:0/22:6-PE+blood-18:2-LPA+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.00362	0.228	up	no	dn	no	no	no	DM-LS
Faecalibacterium	C-peptide	Faecalibacterium-L-Tryptophan+stool+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	C-peptide	Faecalibacterium-Cysteine+blood+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	C-peptide	Faecalibacterium+d18:1-24:1-SM+blood-L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	C-peptide	Faecalibacterium-Cysteine+blood+L-Leucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	C-peptide	Faecalibacterium-Cysteine+blood+L-Isoleucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	C-peptide	Faecalibacterium-Cysteine+blood+Valine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	C-peptide	Faecalibacterium-16:0/18:1-PC+blood+16:0/20:3-PC+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	C-peptide	Faecalibacterium-16:0/18:2-PC+blood+16:0/20:3-PC+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	C-peptide	Faecalibacterium-16:1/16:1-PC+blood-18:0-LPA+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	C-peptide	Faecalibacterium-Phenylacetic acid+stool-18:0-LPA+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	C-peptide	Faecalibacterium-L-Tryptophan+stool-18:0-LPA+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	C-peptide	Faecalibacterium-16:1/16:1-PC+blood-20:1-LPA+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	C-peptide	Faecalibacterium-16:0/18:2-PC+blood+DMG+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	C-peptide	Faecalibacterium-16:0/18:1-PC+blood+18:1/18:1-PC+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	C-peptide	Faecalibacterium-16:0/18:2-PC+blood+18:1/18:1-PC+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	DM-LS
TUDCA+blood	C-peptide	TUDCA+blood+Eotaxin+IL-4-IL-8-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.228	no	no	dn	no	no	no	DM-LS
TUDCA+blood	C-peptide	TUDCA+blood+Eotaxin-GM-CSF+IL-8-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.228	no	no	dn	no	no	no	DM-LS
TUDCA+blood	C-peptide	TUDCA+blood+Eotaxin+IL-17A-IL-8-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.228	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	C-peptide	isocapric acid iso-C6+blood-n3+blood+Taurine+blood+Valine+blood+C-peptide	Indirect	serum_scfa	DM-associated hormones	0.0458	0.228	no	no	dn	no	no	no	DM-LS
Bacteroides	C-peptide	Bacteroides+22:6n3+blood+L-Isoleucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.000267	0.228	dn	dn	up	no	no	no	DM-LS
Propionic acid+stool	C-peptide	Propionic acid+stool-18:2-LPA+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0436	0.228	dn	no	up	no	no	no	DM-LS
[Ruminococcus]	C-peptide	[Ruminococcus]-15-HETE+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.0679	0.228	no	no	dn	no	no	no	DM-LS
GUDCA+blood	C-peptide	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-17A-IL-8-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.228	no	no	dn	no	no	no	DM-LS
GUDCA+blood	C-peptide	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-8-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.228	no	no	dn	no	no	no	DM-LS
GUDCA+blood	C-peptide	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-4-IL-8-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.228	no	no	dn	no	no	no	DM-LS
Acetic acid+stool	C-peptide	Acetic acid+stool-Cysteine+blood+Valine+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0656	0.228	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	C-peptide	Acetic acid+stool-Cysteine+blood+L-Leucine+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0656	0.228	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	C-peptide	Acetic acid+stool+Propionic acid+stool-18:2-LPA+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0656	0.228	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	C-peptide	Acetic acid+stool-Cysteine+blood+L-Isoleucine+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0656	0.228	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	C-peptide	Acetic acid+stool+AA+blood+Choline+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0656	0.228	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	C-peptide	Acetic acid+stool-Cysteine+blood+L-Tyrosine+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0656	0.228	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	C-peptide	Acetic acid+stool-Phenylacetic acid+stool-18:0-LPA+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0656	0.228	dn	no	no	no	no	no	DM-LS
Alistipes	C-peptide	Alistipes-L-Arginine+blood+Valine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0114	0.228	no	up	no	no	no	no	DM-LS
Alistipes	C-peptide	Alistipes-L-Arginine+blood+L-Leucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0114	0.228	no	up	no	no	no	no	DM-LS
Alistipes	C-peptide	Alistipes+12-ketoDCA+stool+LCA+stool-C-peptide	Indirect	Genus	DM-associated hormones	0.0114	0.228	no	up	no	no	no	no	DM-LS
Alistipes	C-peptide	Alistipes+12-ketoDCA+stool+HDCA+stool-C-peptide	Indirect	Genus	DM-associated hormones	0.0114	0.228	no	up	no	no	no	no	DM-LS
Butyricimonas	C-peptide	Butyricimonas+L-Lysine+blood+Valine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-LS
Butyricimonas	C-peptide	Butyricimonas+L-Histidine+blood+Valine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-LS
Butyricimonas	C-peptide	Butyricimonas+L-Lysine+blood+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-LS
Butyricimonas	C-peptide	Butyricimonas+L-Histidine+blood+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-LS
Butyricimonas	C-peptide	Butyricimonas-d18:1-24:1-SM+blood-L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-LS
Butyricimonas	C-peptide	Butyricimonas-Prion disease+18:0-LPA+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-LS
Butyricimonas	C-peptide	Butyricimonas-Cardiac muscle contraction+18:0-LPA+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-LS
Butyricimonas	C-peptide	Butyricimonas+L-Histidine+blood+L-Leucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-LS
Butyricimonas	C-peptide	Butyricimonas+L-Histidine+blood+L-Isoleucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-LS
Butyricimonas	C-peptide	Butyricimonas-d18:0-24:1-SM+blood-DMG+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-LS
Butyricimonas	C-peptide	Butyricimonas-d18:1-14:0-SM+blood-DMG+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	DM-LS
Collinsella	C-peptide	Collinsella-HDCA+stool-C-peptide	Indirect	Genus	DM-associated hormones	0.128	0.228	no	no	no	no	no	no	DM-LS
Collinsella	C-peptide	Collinsella+20:1-LPA+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.128	0.228	no	no	no	no	no	no	DM-LS
Collinsella	C-peptide	Collinsella-LCA+stool-C-peptide	Indirect	Genus	DM-associated hormones	0.128	0.228	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	C-peptide	total_blood_scfa+blood+TUDCA+blood+Eotaxin+IL-4-IL-8-C-peptide	Indirect	serum_scfa	DM-associated hormones	0.168	0.228	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	C-peptide	total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-8-C-peptide	Indirect	serum_scfa	DM-associated hormones	0.168	0.228	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	C-peptide	total_blood_scfa+blood+TUDCA+blood+Eotaxin+IL-17A-IL-8-C-peptide	Indirect	serum_scfa	DM-associated hormones	0.168	0.228	no	no	no	no	no	no	DM-LS
[Eubacterium]	C-peptide	[Eubacterium]-Viral myocarditis-L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0692	0.228	no	no	no	no	no	no	DM-LS
[Eubacterium]	C-peptide	[Eubacterium]-Salmonella infection-L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0692	0.228	no	no	no	no	no	no	DM-LS
[Eubacterium]	C-peptide	[Eubacterium]-Viral myocarditis-Valine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.0692	0.228	no	no	no	no	no	no	DM-LS
LCA+stool	C-peptide	LCA+stool-C-peptide	Direct	stool_bileacids	DM-associated hormones	0.314	0.228	no	no	no	no	no	no	DM-LS
Akkermansia	C-peptide	Akkermansia+LCA+stool-C-peptide	Indirect	Genus	DM-associated hormones	0.23	0.228	no	no	no	no	no	no	DM-LS
Bifidobacterium	C-peptide	Bifidobacterium-18:2/20:4-PC+blood+20:3/16:0-PC+blood+DMG+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.105	0.228	no	dn	no	no	no	no	DM-LS
Bifidobacterium	C-peptide	Bifidobacterium+Glycine+blood+L-Glutamine+blood+L-Isoleucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.105	0.228	no	dn	no	no	no	no	DM-LS
Bifidobacterium	C-peptide	Bifidobacterium+Chemical carcinogenesis - receptor activation-L-Glutamine+blood+L-Isoleucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.105	0.228	no	dn	no	no	no	no	DM-LS
Bifidobacterium	C-peptide	Bifidobacterium+Glycine+blood+L-Asparagine+blood+L-Isoleucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.105	0.228	no	dn	no	no	no	no	DM-LS
Bifidobacterium	C-peptide	Bifidobacterium-FGF basic+IL-17A-IL-8-C-peptide	Indirect	Genus	DM-associated hormones	0.105	0.228	no	dn	no	no	no	no	DM-LS
Bifidobacterium	C-peptide	Bifidobacterium+Glycine+blood+L-Arginine+blood+L-Leucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.105	0.228	no	dn	no	no	no	no	DM-LS
Bifidobacterium	C-peptide	Bifidobacterium+Chemical carcinogenesis - receptor activation+16:0/16:0-PC+blood-18:0-LPA+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.105	0.228	no	dn	no	no	no	no	DM-LS
Bifidobacterium	C-peptide	Bifidobacterium+Glycine+blood+L-Arginine+blood+Valine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.105	0.228	no	dn	no	no	no	no	DM-LS
Bifidobacterium	C-peptide	Bifidobacterium+d18:1-18:1-SM+blood-L-Ornithine+blood+Valine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.105	0.228	no	dn	no	no	no	no	DM-LS
Bifidobacterium	C-peptide	Bifidobacterium+Glycine+blood+SFA%+blood+Valine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.105	0.228	no	dn	no	no	no	no	DM-LS
Ruminococcus	C-peptide	Ruminococcus+Cell adhesion molecules-Valine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.335	0.228	no	no	no	no	no	no	DM-LS
Ruminococcus	C-peptide	Ruminococcus+Cell adhesion molecules-L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.335	0.228	no	no	no	no	no	no	DM-LS
Ruminococcus	C-peptide	Ruminococcus+22:6n3+blood+L-Isoleucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.335	0.228	no	no	no	no	no	no	DM-LS
GCDCA+blood	C-peptide	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4-IL-8-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.31	0.228	no	no	no	no	no	no	DM-LS
GCDCA+blood	C-peptide	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-8-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.31	0.228	no	no	no	no	no	no	DM-LS
GCDCA+blood	C-peptide	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-8-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.31	0.228	no	no	no	no	no	no	DM-LS
Succinivibrio	C-peptide	Succinivibrio-L-Tyrosine+stool+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.138	0.228	no	no	no	no	no	no	DM-LS
Succinivibrio	C-peptide	Succinivibrio-L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.138	0.228	no	no	no	no	no	no	DM-LS
ACA+blood	C-peptide	ACA+blood-DL-methionine sulfoxide+blood+L-Isoleucine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.338	0.228	no	no	no	no	no	no	DM-LS
ACA+blood	C-peptide	ACA+blood-DL-methionine sulfoxide+blood+L-Tyrosine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.338	0.228	no	no	no	no	no	no	DM-LS
DCA+stool	C-peptide	DCA+stool-16:0/20:3-PC+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.195	0.228	no	no	no	no	no	no	DM-LS
DCA+stool	C-peptide	DCA+stool-18:1/18:1-PC+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.195	0.228	no	no	no	no	no	no	DM-LS
DCA+stool	C-peptide	DCA+stool+HDCA+stool-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.195	0.228	no	no	no	no	no	no	DM-LS
DCA+stool	C-peptide	DCA+stool-18:2-LPA+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.195	0.228	no	no	no	no	no	no	DM-LS
DCA+stool	C-peptide	DCA+stool+LCA+stool-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.195	0.228	no	no	no	no	no	no	DM-LS
Butyric acid+stool	C-peptide	Butyric acid+stool-16:1/16:1-PC+blood-20:1-LPA+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.102	0.228	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	C-peptide	Butyric acid+stool+AA+blood+Choline+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.102	0.228	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	C-peptide	Butyric acid+stool-Phenylacetic acid+stool-18:0-LPA+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.102	0.228	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	C-peptide	Butyric acid+stool-16:1/16:1-PC+blood-18:0-LPA+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.102	0.228	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	C-peptide	Butyric acid+stool+Propionic acid+stool-18:2-LPA+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.102	0.228	dn	no	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	C-peptide	4-hydroxybenzoic acid+stool-HDCA+stool-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.228	no	dn	no	no	no	no	DM-LS
GCA+blood	C-peptide	GCA+blood+FGF basic+IL-17A-IL-8-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.16	0.228	no	no	no	no	no	no	DM-LS
ACA+stool	C-peptide	ACA+stool-L-Citrulline+blood+L-Leucine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.417	0.228	no	no	no	no	no	no	DM-LS
ACA+stool	C-peptide	ACA+stool-L-Citrulline+blood+L-Isoleucine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.417	0.228	no	no	no	no	no	no	DM-LS
ACA+stool	C-peptide	ACA+stool-L-Citrulline+blood+Valine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.417	0.228	no	no	no	no	no	no	DM-LS
ACA+stool	C-peptide	ACA+stool+16:0-LPC+blood+18:0-LPA+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.417	0.228	no	no	no	no	no	no	DM-LS
CDCA+blood	C-peptide	CDCA+blood-Cysteine+blood+L-Leucine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.506	0.228	no	no	no	no	no	no	DM-LS
CDCA+blood	C-peptide	CDCA+blood+d18:1-14:1-SM+blood-DMG+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.506	0.228	no	no	no	no	no	no	DM-LS
CDCA+blood	C-peptide	CDCA+blood-Cysteine+blood+L-Tyrosine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.506	0.228	no	no	no	no	no	no	DM-LS
CDCA+blood	C-peptide	CDCA+blood-L-Tryptophan+blood+L-Tyrosine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.506	0.228	no	no	no	no	no	no	DM-LS
CDCA+blood	C-peptide	CDCA+blood-L-Methionine+blood+L-Tyrosine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.506	0.228	no	no	no	no	no	no	DM-LS
CDCA+blood	C-peptide	CDCA+blood-Cysteine+blood+Valine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.506	0.228	no	no	no	no	no	no	DM-LS
CDCA+blood	C-peptide	CDCA+blood-L-Tryptophan+blood+Valine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.506	0.228	no	no	no	no	no	no	DM-LS
CDCA+blood	C-peptide	CDCA+blood-L-Methionine+blood+Valine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.506	0.228	no	no	no	no	no	no	DM-LS
CDCA+blood	C-peptide	CDCA+blood+d18:1-14:1-SM+blood-L-Isoleucine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.506	0.228	no	no	no	no	no	no	DM-LS
CDCA+blood	C-peptide	CDCA+blood-Cysteine+blood+L-Isoleucine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.506	0.228	no	no	no	no	no	no	DM-LS
capric acid C6+blood	C-peptide	capric acid C6+blood+L-Glutamine+blood+L-Isoleucine+blood+C-peptide	Indirect	serum_scfa	DM-associated hormones	0.433	0.228	no	no	no	no	no	no	DM-LS
capric acid C6+blood	C-peptide	capric acid C6+blood-d18:1-16:1-SM+blood-L-Isoleucine+blood+C-peptide	Indirect	serum_scfa	DM-associated hormones	0.433	0.228	no	no	no	no	no	no	DM-LS
capric acid C6+blood	C-peptide	capric acid C6+blood+L-Asparagine+blood+L-Isoleucine+blood+C-peptide	Indirect	serum_scfa	DM-associated hormones	0.433	0.228	no	no	no	no	no	no	DM-LS
capric acid C6+blood	C-peptide	capric acid C6+blood+L-Tryptophan+blood+Valine+blood+C-peptide	Indirect	serum_scfa	DM-associated hormones	0.433	0.228	no	no	no	no	no	no	DM-LS
capric acid C6+blood	C-peptide	capric acid C6+blood+octanoic acid C8+blood+Valine+blood+C-peptide	Indirect	serum_scfa	DM-associated hormones	0.433	0.228	no	no	no	no	no	no	DM-LS
capric acid C6+blood	C-peptide	capric acid C6+blood+L-Tryptophan+blood+L-Tyrosine+blood+C-peptide	Indirect	serum_scfa	DM-associated hormones	0.433	0.228	no	no	no	no	no	no	DM-LS
Pyramidobacter	C-peptide	"Pyramidobacter+Parathyroid hormone synthesis, secretion and action-C-peptide"	Indirect	Genus	DM-associated hormones	0.45	0.228	no	no	no	no	no	no	DM-LS
Pyramidobacter	C-peptide	Pyramidobacter+HDCA+stool-C-peptide	Indirect	Genus	DM-associated hormones	0.45	0.228	no	no	no	no	no	no	DM-LS
Prevotella	C-peptide	Prevotella+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	DM-LS
Prevotella	C-peptide	Prevotella+L-Leucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	DM-LS
TCA+blood	C-peptide	TCA+blood+FGF basic+IL-17A-IL-8-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.339	0.228	no	no	no	no	no	no	DM-LS
iso-DCA+blood	C-peptide	iso-DCA+blood+Valine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.38	0.228	no	no	no	no	no	no	DM-LS
iso-DCA+blood	C-peptide	iso-DCA+blood+L-Leucine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.38	0.228	no	no	no	no	no	no	DM-LS
HCA+stool	C-peptide	HCA+stool+18:0-LPA+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.155	0.228	no	no	no	no	no	no	DM-LS
Roseburia	C-peptide	Roseburia-Valine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.495	0.228	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	C-peptide	12-ketoDCA+stool+HDCA+stool-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.505	0.228	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	C-peptide	12-ketoDCA+stool+LCA+stool-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.505	0.228	no	no	no	no	no	no	DM-LS
GLCA+blood	C-peptide	GLCA+blood-PUFA/MUFA+blood+TXB2+blood+Valine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.319	0.228	no	no	no	no	no	no	DM-LS
GLCA+blood	C-peptide	GLCA+blood-PUFA/MUFA+blood+SFA%+blood+Valine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.319	0.228	no	no	no	no	no	no	DM-LS
GLCA+blood	C-peptide	GLCA+blood+HDCA+blood+L-Ornithine+blood+Valine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.319	0.228	no	no	no	no	no	no	DM-LS
GLCA+blood	C-peptide	GLCA+blood+iso-LCA+blood+L-Ornithine+blood+Valine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.319	0.228	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	C-peptide	L-Tryptophan+stool-18:0-LPA+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.228	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	C-peptide	L-Tryptophan+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.228	no	no	no	no	no	no	DM-LS
CA+blood	C-peptide	CA+blood-Cysteine+blood+Valine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.606	0.228	no	no	no	no	no	no	DM-LS
CA+blood	C-peptide	CA+blood-Cysteine+blood+L-Tyrosine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.606	0.228	no	no	no	no	no	no	DM-LS
CA+blood	C-peptide	CA+blood-Cysteine+blood+L-Leucine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.606	0.228	no	no	no	no	no	no	DM-LS
CA+blood	C-peptide	CA+blood-Cysteine+blood+L-Isoleucine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.606	0.228	no	no	no	no	no	no	DM-LS
CA+blood	C-peptide	CA+blood-L-Glutamine+blood+L-Isoleucine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.606	0.228	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	C-peptide	L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.228	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	C-peptide	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood+SFA%+blood+Valine+blood+C-peptide	Indirect	serum_scfa	DM-associated hormones	0.407	0.228	no	no	no	no	no	no	DM-LS
GCA+stool	C-peptide	GCA+stool+GDCA+stool-L-Isoleucine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.228	no	no	no	no	no	no	DM-LS
GCA+stool	C-peptide	GCA+stool+GCDCA+stool-L-Isoleucine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.228	no	no	no	no	no	no	DM-LS
GCA+stool	C-peptide	GCA+stool+16:0/18:1-PC+blood+16:0/20:3-PC+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.228	no	no	no	no	no	no	DM-LS
GCA+stool	C-peptide	GCA+stool+TCA+stool+16:0/20:3-PC+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.228	no	no	no	no	no	no	DM-LS
GCA+stool	C-peptide	GCA+stool-TXB2+blood+Valine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.228	no	no	no	no	no	no	DM-LS
GCA+stool	C-peptide	GCA+stool+16:0/18:1-PC+blood+18:1/18:1-PC+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.228	no	no	no	no	no	no	DM-LS
GCA+stool	C-peptide	GCA+stool+18:0/16:0-PC+blood+18:1/18:1-PC+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.228	no	no	no	no	no	no	DM-LS
GCA+stool	C-peptide	GCA+stool+TCA+stool+18:1/18:1-PC+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.228	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	C-peptide	T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-8-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.478	0.228	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	C-peptide	T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4-IL-8-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.478	0.228	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	C-peptide	T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-8-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.478	0.228	no	no	no	no	no	no	DM-LS
Coprococcus	C-peptide	Coprococcus+LCA+stool-C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	DM-LS
Oscillospira	C-peptide	Oscillospira+Valine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	DM-LS
HCA+blood	C-peptide	HCA+blood-MUFA+blood-PUFA/MUFA+blood+TXB2+blood+Valine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.544	0.228	no	no	no	no	no	no	DM-LS
HCA+blood	C-peptide	HCA+blood-MUFA+blood-PUFA/MUFA+blood+SFA%+blood+Valine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.544	0.228	no	no	no	no	no	no	DM-LS
HCA+blood	C-peptide	HCA+blood-MUFA+blood+MUFA%+blood+SFA%+blood+Valine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.544	0.228	no	no	no	no	no	no	DM-LS
iso-LCA+stool	C-peptide	iso-LCA+stool+LCA+stool-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.72	0.228	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	C-peptide	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+L-Leucine+blood+C-peptide	Indirect	serum_scfa	DM-associated hormones	0.262	0.228	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	C-peptide	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+L-Isoleucine+blood+C-peptide	Indirect	serum_scfa	DM-associated hormones	0.262	0.228	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	C-peptide	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+Valine+blood+C-peptide	Indirect	serum_scfa	DM-associated hormones	0.262	0.228	no	no	no	no	no	no	DM-LS
DCA+blood	C-peptide	DCA+blood-L-Glutamine+blood+L-Isoleucine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.122	0.228	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	C-peptide	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood+DMG+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.228	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	C-peptide	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+DMG+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.228	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	C-peptide	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood-DMG+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.228	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	C-peptide	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2/16:0-PC+blood+DMG+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.228	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	C-peptide	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood+18:1/18:1-PC+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.228	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	C-peptide	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+18:1/18:1-PC+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.228	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	C-peptide	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2n6c+blood-20:1-LPA+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.228	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	C-peptide	3-(3-Hydroxyphenyl)propanoic acid+stool-18:3/18:2-PC+blood-L-Isoleucine+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.228	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	C-peptide	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-18:0-LPA+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.228	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	C-peptide	Indole-3-Acetic acid+stool+L-Tryptophan+stool-18:0-LPA+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.228	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	C-peptide	Indole-3-Acetic acid+stool+L-Tryptophan+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.228	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	C-peptide	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.228	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	C-peptide	Indole-3-Acetic acid+stool+L-Tyrosine+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.228	no	no	no	no	no	no	DM-LS
TCA+stool	C-peptide	TCA+stool+18:1/18:1-PC+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.458	0.228	no	no	no	no	no	no	DM-LS
TCA+stool	C-peptide	TCA+stool+16:0/20:3-PC+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.458	0.228	no	no	no	no	no	no	DM-LS
HDCA+stool	C-peptide	HDCA+stool-C-peptide	Direct	stool_bileacids	DM-associated hormones	0.176	0.228	no	no	no	no	no	no	DM-LS
Lachnospira	C-peptide	Lachnospira+18:1/18:1-PC+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-LS
Lachnospira	C-peptide	Lachnospira+Choline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-LS
Lachnospira	C-peptide	Lachnospira+16:0/20:3-PC+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	DM-LS
Fusobacterium	C-peptide	Fusobacterium+16:0/20:3-PC+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.628	0.228	no	no	no	no	no	no	DM-LS
Fusobacterium	C-peptide	Fusobacterium+18:1/18:1-PC+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.628	0.228	no	no	no	no	no	no	DM-LS
isobutyric acid C4+blood	C-peptide	isobutyric acid C4+blood+MUFA%+blood+SFA%+blood+Valine+blood+C-peptide	Indirect	serum_scfa	DM-associated hormones	0.0151	0.228	up	up	no	no	no	no	DM-LS
GCDCA+stool	C-peptide	GCDCA+stool-L-Isoleucine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.228	no	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	C-peptide	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.228	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	C-peptide	5-Hydroxytryptamine+stool+L-Tyrosine+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.228	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	C-peptide	5-Hydroxytryptamine+stool-Propionic acid+stool-18:2-LPA+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.228	dn	dn	no	no	no	no	DM-LS
Odoribacter	C-peptide	Odoribacter+IL-8-C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-LS
Odoribacter	C-peptide	Odoribacter+Choline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	C-peptide	Isobutyric acid+stool+L-Tryptophan+stool-18:0-LPA+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.408	0.228	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	C-peptide	Isobutyric acid+stool+Phenylacetic acid+stool-18:0-LPA+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.408	0.228	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	C-peptide	Isobutyric acid+stool+L-Tyrosine+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.408	0.228	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	C-peptide	Isobutyric acid+stool+L-Tryptophan+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.408	0.228	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	C-peptide	Isobutyric acid+stool+L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.408	0.228	no	no	no	no	no	no	DM-LS
Lachnobacterium	C-peptide	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-8-C-peptide	Indirect	Genus	DM-associated hormones	0.867	0.228	no	no	no	no	no	no	DM-LS
Lachnobacterium	C-peptide	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4-IL-8-C-peptide	Indirect	Genus	DM-associated hormones	0.867	0.228	no	no	no	no	no	no	DM-LS
Lachnobacterium	C-peptide	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-8-C-peptide	Indirect	Genus	DM-associated hormones	0.867	0.228	no	no	no	no	no	no	DM-LS
Kynurenic acid+stool	C-peptide	Kynurenic acid+stool+L-Tyrosine+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.228	dn	dn	no	no	no	no	DM-LS
Anaerostipes	C-peptide	Anaerostipes+15-HETE+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.568	0.228	no	no	no	no	no	no	DM-LS
Anaerostipes	C-peptide	Anaerostipes-L-Isoleucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.568	0.228	no	no	no	no	no	no	DM-LS
TUDCA+stool	C-peptide	TUDCA+stool-UDCA+stool-16:0/16:0-PC+blood-18:0-LPA+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.241	0.228	no	no	no	no	no	no	DM-LS
TUDCA+stool	C-peptide	TUDCA+stool-UDCA+stool-18:2/16:0-PC+blood+DMG+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.241	0.228	no	no	no	no	no	no	DM-LS
TUDCA+stool	C-peptide	TUDCA+stool-UDCA+stool-16:0/22:6-PC+blood+DMG+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.241	0.228	no	no	no	no	no	no	DM-LS
TUDCA+stool	C-peptide	TUDCA+stool-UDCA+stool-16:0/18:2-PC+blood+DMG+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.241	0.228	no	no	no	no	no	no	DM-LS
TUDCA+stool	C-peptide	TUDCA+stool-UDCA+stool-16:0/18:2-PC+blood+16:0/20:3-PC+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.241	0.228	no	no	no	no	no	no	DM-LS
TUDCA+stool	C-peptide	TUDCA+stool-UDCA+stool-16:0/18:2-PC+blood+18:1/18:1-PC+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.241	0.228	no	no	no	no	no	no	DM-LS
TUDCA+stool	C-peptide	TUDCA+stool-UDCA+stool-18:2n6c+blood-20:1-LPA+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.241	0.228	no	no	no	no	no	no	DM-LS
TUDCA+stool	C-peptide	TUDCA+stool-UDCA+stool-18:3n3+blood-20:1-LPA+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.241	0.228	no	no	no	no	no	no	DM-LS
TUDCA+stool	C-peptide	TUDCA+stool-UDCA+stool+d18:1-16:1-SM+blood-L-Isoleucine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.241	0.228	no	no	no	no	no	no	DM-LS
TUDCA+stool	C-peptide	TUDCA+stool-UDCA+stool-L-Ornithine+blood+Valine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.241	0.228	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	C-peptide	Isovaleric acid+stool+L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.343	0.228	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	C-peptide	Isovaleric acid+stool+L-Tyrosine+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.343	0.228	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	C-peptide	Isovaleric acid+stool+L-Tryptophan+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.343	0.228	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	C-peptide	Isovaleric acid+stool+Phenylacetic acid+stool-18:0-LPA+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.343	0.228	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	C-peptide	Isovaleric acid+stool+L-Tryptophan+stool-18:0-LPA+blood+C-peptide	Indirect	stool_scfa	DM-associated hormones	0.343	0.228	no	no	no	no	no	no	DM-LS
Paraprevotella	C-peptide	Paraprevotella+Betaine+blood+Valine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.118	0.228	no	no	no	no	no	no	DM-LS
Paraprevotella	C-peptide	Paraprevotella+Arachidonic acid metabolism-HDCA+stool-C-peptide	Indirect	Genus	DM-associated hormones	0.118	0.228	no	no	no	no	no	no	DM-LS
Paraprevotella	C-peptide	Paraprevotella+Arachidonic acid metabolism+Choline+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.118	0.228	no	no	no	no	no	no	DM-LS
Paraprevotella	C-peptide	Paraprevotella+Betaine+blood+L-Isoleucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.118	0.228	no	no	no	no	no	no	DM-LS
iso-LCA+blood	C-peptide	iso-LCA+blood+L-Ornithine+blood+Valine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.507	0.228	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	C-peptide	Phenylacetic acid+stool-18:0-LPA+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.228	no	no	no	no	no	no	DM-LS
Gemmiger	C-peptide	Gemmiger+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.595	0.228	no	no	no	no	no	no	DM-LS
GDCA+stool	C-peptide	GDCA+stool-L-Isoleucine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.656	0.228	no	no	no	no	no	no	DM-LS
Methanobrevibacter	C-peptide	Methanobrevibacter+Valine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.629	0.228	no	no	no	no	no	no	DM-LS
Methanobrevibacter	C-peptide	Methanobrevibacter+L-Leucine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.629	0.228	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	C-peptide	L-Tyrosine+stool+L-Tyrosine+blood+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.228	no	no	no	no	no	no	DM-LS
CDCA+stool	C-peptide	CDCA+stool-LCA+stool-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.663	0.228	no	no	no	no	no	no	DM-LS
CDCA+stool	C-peptide	CDCA+stool-HDCA+stool-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.663	0.228	no	no	no	no	no	no	DM-LS
CDCA+stool	C-peptide	CDCA+stool+18:0-LPA+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.663	0.228	no	no	no	no	no	no	DM-LS
CA+stool	C-peptide	CA+stool-HDCA+stool-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.827	0.228	no	no	no	no	no	no	DM-LS
CA+stool	C-peptide	CA+stool-LCA+stool-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.827	0.228	no	no	no	no	no	no	DM-LS
Slackia	C-peptide	Slackia-15-HETE+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.94	0.228	no	no	no	no	no	no	DM-LS
HDCA+blood	C-peptide	HDCA+blood+L-Ornithine+blood+Valine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.483	0.228	no	no	no	no	no	no	DM-LS
UDCA+stool	C-peptide	UDCA+stool-16:0/16:0-PC+blood-18:0-LPA+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.266	0.228	no	no	no	no	no	no	DM-LS
UDCA+stool	C-peptide	UDCA+stool-18:2/16:0-PC+blood+DMG+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.266	0.228	no	no	no	no	no	no	DM-LS
UDCA+stool	C-peptide	UDCA+stool-16:0/22:6-PC+blood+DMG+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.266	0.228	no	no	no	no	no	no	DM-LS
UDCA+stool	C-peptide	UDCA+stool-16:0/18:2-PC+blood+DMG+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.266	0.228	no	no	no	no	no	no	DM-LS
UDCA+stool	C-peptide	UDCA+stool-16:0/18:2-PC+blood+16:0/20:3-PC+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.266	0.228	no	no	no	no	no	no	DM-LS
UDCA+stool	C-peptide	UDCA+stool-16:0/18:2-PC+blood+18:1/18:1-PC+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.266	0.228	no	no	no	no	no	no	DM-LS
UDCA+stool	C-peptide	UDCA+stool-18:2n6c+blood-20:1-LPA+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.266	0.228	no	no	no	no	no	no	DM-LS
UDCA+stool	C-peptide	UDCA+stool-18:3n3+blood-20:1-LPA+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.266	0.228	no	no	no	no	no	no	DM-LS
UDCA+stool	C-peptide	UDCA+stool+d18:1-16:1-SM+blood-L-Isoleucine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.266	0.228	no	no	no	no	no	no	DM-LS
UDCA+stool	C-peptide	UDCA+stool-L-Ornithine+blood+Valine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.266	0.228	no	no	no	no	no	no	DM-LS
TDCA+stool	C-peptide	TDCA+stool+UDCA+stool-16:0/16:0-PC+blood-18:0-LPA+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-LS
TDCA+stool	C-peptide	TDCA+stool+UDCA+stool-18:2/16:0-PC+blood+DMG+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-LS
TDCA+stool	C-peptide	TDCA+stool+UDCA+stool-16:0/22:6-PC+blood+DMG+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-LS
TDCA+stool	C-peptide	TDCA+stool+UDCA+stool-16:0/18:2-PC+blood+DMG+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-LS
TDCA+stool	C-peptide	TDCA+stool+UDCA+stool-16:0/18:2-PC+blood+16:0/20:3-PC+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-LS
TDCA+stool	C-peptide	TDCA+stool+UDCA+stool-16:0/18:2-PC+blood+18:1/18:1-PC+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-LS
TDCA+stool	C-peptide	TDCA+stool+UDCA+stool-18:2n6c+blood-20:1-LPA+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-LS
TDCA+stool	C-peptide	TDCA+stool+UDCA+stool-18:3n3+blood-20:1-LPA+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-LS
TDCA+stool	C-peptide	TDCA+stool+UDCA+stool+d18:1-16:1-SM+blood-L-Isoleucine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-LS
TDCA+stool	C-peptide	TDCA+stool+UDCA+stool-L-Ornithine+blood+Valine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.963	0.228	no	no	no	no	no	no	DM-LS
nutriCA+stool	C-peptide	nutriCA+stool-18:2n6c+blood-20:1-LPA+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.481	0.228	no	no	no	no	no	no	DM-LS
nutriCA+stool	C-peptide	nutriCA+stool-18:3n3+blood-20:1-LPA+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.481	0.228	no	no	no	no	no	no	DM-LS
nutriCA+stool	C-peptide	nutriCA+stool-TXB2+blood+Valine+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.481	0.228	no	no	no	no	no	no	DM-LS
nutriCA+stool	C-peptide	nutriCA+stool-16:0/16:0-PC+blood-18:0-LPA+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.481	0.228	no	no	no	no	no	no	DM-LS
nutriCA+stool	C-peptide	nutriCA+stool-Phenylacetic acid+stool-18:0-LPA+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.481	0.228	no	no	no	no	no	no	DM-LS
GDCA+blood	C-peptide	GDCA+blood+iso-LCA+blood+L-Ornithine+blood+Valine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.632	0.228	no	no	no	no	no	no	DM-LS
acetic acid C2+blood	C-peptide	acetic acid C2+blood-d18:1-14:1-SM+blood-L-Isoleucine+blood+C-peptide	Indirect	serum_scfa	DM-associated hormones	0.000193	0.228	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	C-peptide	acetic acid C2+blood-d18:1-14:1-SM+blood-DMG+blood+C-peptide	Indirect	serum_scfa	DM-associated hormones	0.000193	0.228	up	dn	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	C-peptide	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-4-IL-8-C-peptide	Indirect	serum_scfa	DM-associated hormones	0.117	0.228	no	no	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	C-peptide	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-8-C-peptide	Indirect	serum_scfa	DM-associated hormones	0.117	0.228	no	no	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	C-peptide	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-17A-IL-8-C-peptide	Indirect	serum_scfa	DM-associated hormones	0.117	0.228	no	no	no	no	no	no	DM-LS
Adlercreutzia	C-peptide	Adlercreutzia+18:1-LPC+blood-L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.548	0.228	no	no	no	no	no	no	DM-LS
Adlercreutzia	C-peptide	Adlercreutzia-16:0/20:5-PC+blood-18:1/18:1-PC+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.548	0.228	no	no	no	no	no	no	DM-LS
Clostridium	C-peptide	Clostridium+20:1-LPA+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.925	0.228	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	C-peptide	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.48	0.228	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	C-peptide	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.48	0.228	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-20:3-LPE+blood+Choline+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-L-Lysine+blood+L-Tyrosine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-L-Lysine+blood+Valine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-L-Arginine+blood+Valine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood-L-Arginine+blood+L-Leucine+blood+C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus-18:0/18:2-PC+blood+DMG+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus-18:2/16:0-PC+blood+DMG+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus-18:1/18:0-PC+blood+DMG+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus+DCA+stool+HDCA+stool-C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus+DCA+stool+LCA+stool-C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus-Phenylacetic acid+stool-18:0-LPA+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus-L-Tryptophan+stool-18:0-LPA+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus+Viral myocarditis-L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus-L-Phenylalanine+stool+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus+Cell adhesion molecules-L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus-L-Tryptophan+stool+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus-L-Tyrosine+stool+L-Tyrosine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus+Viral myocarditis-Valine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus+Cell adhesion molecules-Valine+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus+DCA+stool-16:0/20:3-PC+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus+DCA+stool-18:2-LPA+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus-18:0/18:2-PC+blood+18:1/18:1-PC+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus+DCA+stool-18:1/18:1-PC+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Butyricicoccus	C-peptide	Butyricicoccus-18:1/18:0-PC+blood+18:1/18:1-PC+blood+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	DM-LS
Blautia	FGF basic	Blautia+GCA+blood+FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	DM-LS
Parabacteroides	FGF basic	Parabacteroides+20:0+blood-FGF basic	Indirect	Genus	serum_cytokines	4.19E-05	0.65	no	up	up	no	no	no	DM-LS
Dorea	FGF basic	Dorea-18:0/22:6-PE+blood+18:3/16:0-PE+blood+20:0+blood-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-LS
Dorea	FGF basic	Dorea-Lipid and atherosclerosis-18:0/22:6-PA+blood-GCA+blood+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-LS
Dorea	FGF basic	Dorea-18:0/22:6-PE+blood-L-2-Aminobutyric acid+blood+TCA+blood+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-LS
Dorea	FGF basic	Dorea-Lipid and atherosclerosis-14:0/18:2-PC+blood+16:0/18:2-PI+blood-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-LS
Dorea	FGF basic	Dorea+d18:1-20:0-SM+blood+d18:1-22:1-SM+blood+L-Alanine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-LS
Dorea	FGF basic	Dorea-18:0/22:6-PE+blood+18:1/22:6-PE+blood-L-Alanine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	DM-LS
Faecalibacterium	FGF basic	Faecalibacterium-Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0039	0.65	no	dn	dn	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+Cytokine-cytokine receptor interaction+Regulation of actin cytoskeleton+FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+Cytokine-cytokine receptor interaction-C-type lectin receptor signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+Cytokine-cytokine receptor interaction-Chronic myeloid leukemia-FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+Cytokine-cytokine receptor interaction-Hepatitis B-FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+Cytokine-cytokine receptor interaction+Focal adhesion+FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+Cytokine-cytokine receptor interaction-Prostate cancer-FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+Cytokine-cytokine receptor interaction+Leukocyte transendothelial migration+FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+Cytokine-cytokine receptor interaction+Hypertrophic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+Cytokine-cytokine receptor interaction+Hippo signaling pathway+FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+Cytokine-cytokine receptor interaction-Insulin resistance-FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+Cytokine-cytokine receptor interaction-NF-kappa B signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+Cytokine-cytokine receptor interaction-Small cell lung cancer-FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+Cytokine-cytokine receptor interaction+Salmonella infection+FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+Cytokine-cytokine receptor interaction-Transcriptional misregulation in cancer-FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+22:6n3+blood-GCA+blood+FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+Cytokine-cytokine receptor interaction+Tight junction+FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+Cytokine-cytokine receptor interaction+Bacterial invasion of epithelial cells+FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Bacteroides	FGF basic	Bacteroides+Cytokine-cytokine receptor interaction+Arrhythmogenic right ventricular cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	DM-LS
Propionic acid+stool	FGF basic	Propionic acid+stool-18:0/18:1-PC+blood+L-Alanine+blood-FGF basic	Indirect	stool_scfa	serum_cytokines	0.0436	0.65	dn	no	up	no	no	no	DM-LS
[Ruminococcus]	FGF basic	[Ruminococcus]-FGF basic	Direct	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	DM-LS
Acetic acid+stool	FGF basic	Acetic acid+stool+18:3n6+blood+L-Alanine+blood-FGF basic	Indirect	stool_scfa	serum_cytokines	0.0656	0.65	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	FGF basic	Acetic acid+stool-Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_scfa	serum_cytokines	0.0656	0.65	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	FGF basic	Acetic acid+stool+18:3n6+blood+Sarcosine+blood-FGF basic	Indirect	stool_scfa	serum_cytokines	0.0656	0.65	dn	no	no	no	no	no	DM-LS
Alistipes	FGF basic	Alistipes+12-ketoDCA+stool-L-Alanine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	DM-LS
Butyricimonas	FGF basic	Butyricimonas-GCA+blood+FGF basic	Indirect	Genus	serum_cytokines	0.17	0.65	no	no	no	no	no	no	DM-LS
Collinsella	FGF basic	Collinsella-Hepatitis B-FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-LS
Collinsella	FGF basic	Collinsella-Insulin resistance-FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-LS
Collinsella	FGF basic	Collinsella-Prostate cancer-FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-LS
Collinsella	FGF basic	Collinsella-NF-kappa B signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	DM-LS
[Eubacterium]	FGF basic	[Eubacterium]-Salmonella infection+FGF basic	Indirect	Genus	serum_cytokines	0.0692	0.65	no	no	no	no	no	no	DM-LS
LCA+stool	FGF basic	LCA+stool+iso-LCA+blood-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.314	0.65	no	no	no	no	no	no	DM-LS
LCA+stool	FGF basic	LCA+stool+GLCA+blood-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.314	0.65	no	no	no	no	no	no	DM-LS
Akkermansia	FGF basic	Akkermansia-L-Alanine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	DM-LS
Bifidobacterium	FGF basic	Bifidobacterium-FGF basic	Direct	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+Type I diabetes mellitus+Rheumatoid arthritis+FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+Phagosome+Rheumatoid arthritis+FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+Cell adhesion molecules+Rheumatoid arthritis+FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+Autoimmune thyroid disease+Rheumatoid arthritis+FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+Type I diabetes mellitus+Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+Allograft rejection+Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus-L-Homocystine+blood-Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+Graft-versus-host disease+Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+Autoimmune thyroid disease+Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+22:6n3+blood-GCA+blood+FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+Phagosome+Bacterial invasion of epithelial cells+FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+Phagosome+Arrhythmogenic right ventricular cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+Phagosome-Chemical carcinogenesis - receptor activation-FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+Phagosome+Hypertrophic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+Phagosome+Leukocyte transendothelial migration+FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+Cell adhesion molecules+Leukocyte transendothelial migration+FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+Phagosome+Salmonella infection+FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+Cell adhesion molecules+Salmonella infection+FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Ruminococcus	FGF basic	Ruminococcus+Phagosome+Tight junction+FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	DM-LS
Succinivibrio	FGF basic	Succinivibrio-Phospholipase D signaling pathway-Longevity regulating pathway - multiple species+FGF basic	Indirect	Genus	serum_cytokines	0.138	0.65	no	no	no	no	no	no	DM-LS
Succinivibrio	FGF basic	Succinivibrio-Phospholipase D signaling pathway+Hepatitis B-FGF basic	Indirect	Genus	serum_cytokines	0.138	0.65	no	no	no	no	no	no	DM-LS
Succinivibrio	FGF basic	Succinivibrio-Phospholipase D signaling pathway-Primary immunodeficiency+FGF basic	Indirect	Genus	serum_cytokines	0.138	0.65	no	no	no	no	no	no	DM-LS
Succinivibrio	FGF basic	Succinivibrio-Phospholipase D signaling pathway+Chemical carcinogenesis - receptor activation-FGF basic	Indirect	Genus	serum_cytokines	0.138	0.65	no	no	no	no	no	no	DM-LS
Succinivibrio	FGF basic	Succinivibrio-Phospholipase D signaling pathway+Relaxin signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.138	0.65	no	no	no	no	no	no	DM-LS
Succinivibrio	FGF basic	"Succinivibrio-Phospholipase D signaling pathway+Growth hormone synthesis, secretion and action-FGF basic"	Indirect	Genus	serum_cytokines	0.138	0.65	no	no	no	no	no	no	DM-LS
Succinivibrio	FGF basic	Succinivibrio-Phospholipase D signaling pathway+Cortisol synthesis and secretion-FGF basic	Indirect	Genus	serum_cytokines	0.138	0.65	no	no	no	no	no	no	DM-LS
Succinivibrio	FGF basic	Succinivibrio-Phospholipase D signaling pathway+Chronic myeloid leukemia-FGF basic	Indirect	Genus	serum_cytokines	0.138	0.65	no	no	no	no	no	no	DM-LS
Succinivibrio	FGF basic	Succinivibrio-Phospholipase D signaling pathway+Insulin secretion-FGF basic	Indirect	Genus	serum_cytokines	0.138	0.65	no	no	no	no	no	no	DM-LS
Succinivibrio	FGF basic	Succinivibrio-Phospholipase D signaling pathway+Cocaine addiction-FGF basic	Indirect	Genus	serum_cytokines	0.138	0.65	no	no	no	no	no	no	DM-LS
ACA+blood	FGF basic	ACA+blood-DL-methionine sulfoxide+blood+EPA+blood-TCA+blood+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.338	0.65	no	no	no	no	no	no	DM-LS
DCA+stool	FGF basic	DCA+stool+iso-LCA+stool-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.195	0.65	no	no	no	no	no	no	DM-LS
DCA+stool	FGF basic	DCA+stool-16:0/20:3-PC+blood+Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.195	0.65	no	no	no	no	no	no	DM-LS
DCA+stool	FGF basic	DCA+stool-18:1/18:1-PC+blood+Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.195	0.65	no	no	no	no	no	no	DM-LS
Butyric acid+stool	FGF basic	Butyric acid+stool-Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_scfa	serum_cytokines	0.102	0.65	dn	no	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	FGF basic	4-hydroxybenzoic acid+stool-Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.65	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	FGF basic	4-hydroxybenzoic acid+stool-HDCA+blood-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.65	no	dn	no	no	no	no	DM-LS
GCA+blood	FGF basic	GCA+blood+FGF basic	Direct	serum_bileacids	serum_cytokines	0.16	0.65	no	no	no	no	no	no	DM-LS
ACA+stool	FGF basic	ACA+stool+Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.417	0.65	no	no	no	no	no	no	DM-LS
CDCA+blood	FGF basic	CDCA+blood+DCA+blood-TCA+blood+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.506	0.65	no	no	no	no	no	no	DM-LS
capric acid C6+blood	FGF basic	capric acid C6+blood-Sarcosine+blood-FGF basic	Indirect	serum_scfa	serum_cytokines	0.433	0.65	no	no	no	no	no	no	DM-LS
capric acid C6+blood	FGF basic	capric acid C6+blood-L-Alanine+blood-FGF basic	Indirect	serum_scfa	serum_cytokines	0.433	0.65	no	no	no	no	no	no	DM-LS
Pyramidobacter	FGF basic	Pyramidobacter+Insulin resistance-FGF basic	Indirect	Genus	serum_cytokines	0.45	0.65	no	no	no	no	no	no	DM-LS
Pyramidobacter	FGF basic	"Pyramidobacter+Parathyroid hormone synthesis, secretion and action-FGF basic"	Indirect	Genus	serum_cytokines	0.45	0.65	no	no	no	no	no	no	DM-LS
Pyramidobacter	FGF basic	Pyramidobacter-Carbon metabolism+FGF basic	Indirect	Genus	serum_cytokines	0.45	0.65	no	no	no	no	no	no	DM-LS
Pyramidobacter	FGF basic	Pyramidobacter+Small cell lung cancer-FGF basic	Indirect	Genus	serum_cytokines	0.45	0.65	no	no	no	no	no	no	DM-LS
Pyramidobacter	FGF basic	Pyramidobacter+Prostate cancer-FGF basic	Indirect	Genus	serum_cytokines	0.45	0.65	no	no	no	no	no	no	DM-LS
Prevotella	FGF basic	Prevotella+cAMP signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	DM-LS
Prevotella	FGF basic	Prevotella+Cocaine addiction-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	DM-LS
Prevotella	FGF basic	Prevotella-Glycolysis / Gluconeogenesis+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	DM-LS
Prevotella	FGF basic	Prevotella+18:0-LPC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	DM-LS
Prevotella	FGF basic	Prevotella+L-Alanine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	DM-LS
Prevotella	FGF basic	Prevotella+Aldosterone synthesis and secretion-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	DM-LS
Prevotella	FGF basic	Prevotella+Insulin secretion-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	DM-LS
Prevotella	FGF basic	Prevotella+Chemical carcinogenesis - receptor activation-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	DM-LS
Prevotella	FGF basic	Prevotella-Carbon metabolism+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	DM-LS
Prevotella	FGF basic	"Prevotella+Growth hormone synthesis, secretion and action-FGF basic"	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	DM-LS
Prevotella	FGF basic	Prevotella+20:0+blood-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	DM-LS
Prevotella	FGF basic	Prevotella+Cortisol synthesis and secretion-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	DM-LS
Prevotella	FGF basic	Prevotella+Calcium signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	DM-LS
TCA+blood	FGF basic	TCA+blood+FGF basic	Direct	serum_bileacids	serum_cytokines	0.339	0.65	no	no	no	no	no	no	DM-LS
HCA+stool	FGF basic	HCA+stool-iso-LCA+stool-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.155	0.65	no	no	no	no	no	no	DM-LS
HCA+stool	FGF basic	HCA+stool-L-Homocystine+blood-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.155	0.65	no	no	no	no	no	no	DM-LS
Roseburia	FGF basic	Roseburia-16:0-LPC+blood+20:0+blood-FGF basic	Indirect	Genus	serum_cytokines	0.495	0.65	no	no	no	no	no	no	DM-LS
Roseburia	FGF basic	Roseburia-16:0-LPC+blood+16:0/18:2-PI+blood-FGF basic	Indirect	Genus	serum_cytokines	0.495	0.65	no	no	no	no	no	no	DM-LS
Roseburia	FGF basic	Roseburia-16:0-LPC+blood+18:0-LPC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.495	0.65	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	FGF basic	12-ketoDCA+stool-L-Alanine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.505	0.65	no	no	no	no	no	no	DM-LS
GLCA+blood	FGF basic	GLCA+blood-Sarcosine+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.319	0.65	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	FGF basic	L-Tryptophan+stool+Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.557	0.65	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	FGF basic	L-Tryptophan+stool-18:3n6+blood+Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.557	0.65	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	FGF basic	L-Tryptophan+stool-18:3n6+blood+L-Alanine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.557	0.65	no	no	no	no	no	no	DM-LS
CA+blood	FGF basic	CA+blood+DCA+blood-TCA+blood+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.606	0.65	no	no	no	no	no	no	DM-LS
CA+blood	FGF basic	CA+blood-capric acid C6+blood-Sarcosine+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.606	0.65	no	no	no	no	no	no	DM-LS
CA+blood	FGF basic	CA+blood-capric acid C6+blood-L-Alanine+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.606	0.65	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	FGF basic	L-Phenylalanine+stool+16:0/18:0-PC+blood+18:0-LPC+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.398	0.65	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	FGF basic	L-Phenylalanine+stool+Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.398	0.65	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	FGF basic	L-Phenylalanine+stool-18:3n6+blood+Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.398	0.65	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	FGF basic	L-Phenylalanine+stool-18:3n6+blood+L-Alanine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.398	0.65	no	no	no	no	no	no	DM-LS
GCA+stool	FGF basic	GCA+stool-DHA+blood-TCA+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0809	0.65	no	no	no	no	no	no	DM-LS
GCA+stool	FGF basic	GCA+stool+L-2-Aminobutyric acid+blood+TCA+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0809	0.65	no	no	no	no	no	no	DM-LS
GCA+stool	FGF basic	GCA+stool+16:0/18:3-PC+blood+L-Alanine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0809	0.65	no	no	no	no	no	no	DM-LS
GCA+stool	FGF basic	GCA+stool+16:0/18:3-PC+blood+Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0809	0.65	no	no	no	no	no	no	DM-LS
Coprococcus	FGF basic	Coprococcus-Aldosterone synthesis and secretion-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	DM-LS
Coprococcus	FGF basic	Coprococcus+Salmonella infection+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	DM-LS
Oscillospira	FGF basic	Oscillospira-Alzheimer disease+Hypertrophic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-LS
Oscillospira	FGF basic	Oscillospira+NOD-like receptor signaling pathway+Transcriptional misregulation in cancer-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-LS
Oscillospira	FGF basic	Oscillospira-Adrenergic signaling in cardiomyocytes+Cocaine addiction-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-LS
Oscillospira	FGF basic	Oscillospira+Peroxisome-L-Alanine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-LS
Oscillospira	FGF basic	Oscillospira-Adrenergic signaling in cardiomyocytes+Chemical carcinogenesis - receptor activation-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-LS
Oscillospira	FGF basic	Oscillospira-Alzheimer disease+GCA+blood+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-LS
Oscillospira	FGF basic	Oscillospira+Peroxisome+Longevity regulating pathway - multiple species+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-LS
Oscillospira	FGF basic	Oscillospira-Adrenergic signaling in cardiomyocytes+Cortisol synthesis and secretion-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-LS
Oscillospira	FGF basic	Oscillospira-Alzheimer disease+Arrhythmogenic right ventricular cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-LS
Oscillospira	FGF basic	"Oscillospira-Adrenergic signaling in cardiomyocytes+Growth hormone synthesis, secretion and action-FGF basic"	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-LS
Oscillospira	FGF basic	Oscillospira-Adrenergic signaling in cardiomyocytes+Insulin secretion-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-LS
Oscillospira	FGF basic	Oscillospira-Adrenergic signaling in cardiomyocytes+Aldosterone synthesis and secretion-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-LS
Oscillospira	FGF basic	Oscillospira+Peroxisome-Aldosterone synthesis and secretion-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-LS
Oscillospira	FGF basic	"Oscillospira-Adrenergic signaling in cardiomyocytes+Parathyroid hormone synthesis, secretion and action-FGF basic"	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-LS
Oscillospira	FGF basic	Oscillospira-Adrenergic signaling in cardiomyocytes+Relaxin signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	DM-LS
iso-LCA+stool	FGF basic	iso-LCA+stool-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.72	0.65	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	FGF basic	2-methyl-butyric acid m-C4+blood-CA+blood+DCA+blood-TCA+blood+FGF basic	Indirect	serum_scfa	serum_cytokines	0.262	0.65	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	FGF basic	2-methyl-butyric acid m-C4+blood-CA+blood-capric acid C6+blood-L-Alanine+blood-FGF basic	Indirect	serum_scfa	serum_cytokines	0.262	0.65	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	FGF basic	2-methyl-butyric acid m-C4+blood-CA+blood-capric acid C6+blood-Sarcosine+blood-FGF basic	Indirect	serum_scfa	serum_cytokines	0.262	0.65	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	FGF basic	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+nonanoic acid C9+blood-Sarcosine+blood-FGF basic	Indirect	serum_scfa	serum_cytokines	0.262	0.65	no	no	no	no	no	no	DM-LS
DCA+blood	FGF basic	DCA+blood-TCA+blood+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.122	0.65	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	FGF basic	3-(3-Hydroxyphenyl)propanoic acid+stool-16:0/18:0-PC+blood+18:0-LPC+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.33	0.65	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	FGF basic	3-(3-Hydroxyphenyl)propanoic acid+stool-iso-LCA+blood-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.33	0.65	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	FGF basic	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.304	0.65	no	no	no	no	no	no	DM-LS
TCA+stool	FGF basic	TCA+stool+18:0/18:1-PC+blood+L-Alanine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.458	0.65	no	no	no	no	no	no	DM-LS
TCA+stool	FGF basic	TCA+stool+18:1/18:1-PC+blood+Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.458	0.65	no	no	no	no	no	no	DM-LS
TCA+stool	FGF basic	TCA+stool+16:0/20:3-PC+blood+Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.458	0.65	no	no	no	no	no	no	DM-LS
HDCA+stool	FGF basic	HDCA+stool-20:2/18:0-PC+blood+L-Alanine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	DM-LS
HDCA+stool	FGF basic	HDCA+stool-18:0/20:3-PC+blood+L-Alanine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	DM-LS
HDCA+stool	FGF basic	HDCA+stool-16:0-LPC+blood+20:0+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	DM-LS
HDCA+stool	FGF basic	HDCA+stool+EPA+blood-TCA+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	DM-LS
HDCA+stool	FGF basic	HDCA+stool-16:0-LPC+blood+16:0/18:2-PI+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	DM-LS
HDCA+stool	FGF basic	HDCA+stool+HDCA+blood-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	DM-LS
HDCA+stool	FGF basic	HDCA+stool+iso-LCA+stool-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	DM-LS
HDCA+stool	FGF basic	HDCA+stool-16:0/20:3-PC+blood+Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	DM-LS
HDCA+stool	FGF basic	HDCA+stool-18:1/18:1-PC+blood+Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	DM-LS
HDCA+stool	FGF basic	HDCA+stool-20:2/18:0-PC+blood+Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	DM-LS
HDCA+stool	FGF basic	HDCA+stool-18:0/20:3-PC+blood+Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	DM-LS
HDCA+stool	FGF basic	HDCA+stool-16:0-LPC+blood+18:0-LPC+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira-Adherens junction-Chronic myeloid leukemia-FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira-Adherens junction+Arrhythmogenic right ventricular cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira-Adherens junction-C-type lectin receptor signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira-Adherens junction+GCA+blood+FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira+18:0+blood-GCA+blood+FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira-d18:0-24:1-SM+blood+L-Alanine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira-Adherens junction-Hepatitis B-FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira-Adherens junction+Hypertrophic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira-Adherens junction-Insulin resistance-FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira-Adherens junction+Leukocyte transendothelial migration+FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira-Adherens junction+Regulation of actin cytoskeleton+FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira-Adherens junction-Prostate cancer-FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira-Adherens junction+Salmonella infection+FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira-Adherens junction-RIG-I-like receptor signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira-Adherens junction-Small cell lung cancer-FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira-Adherens junction+Tight junction+FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira-Adherens junction-Transcriptional misregulation in cancer-FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira-Adherens junction+Bacterial invasion of epithelial cells+FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira+18:1/18:1-PC+blood+Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Lachnospira	FGF basic	Lachnospira+16:0/20:3-PC+blood+Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	DM-LS
Fusobacterium	FGF basic	Fusobacterium+16:0/20:3-PC+blood+Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.628	0.65	no	no	no	no	no	no	DM-LS
Fusobacterium	FGF basic	Fusobacterium+18:1/18:1-PC+blood+Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.628	0.65	no	no	no	no	no	no	DM-LS
GCDCA+stool	FGF basic	GCDCA+stool+18:0/18:1-PC+blood+L-Alanine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	DM-LS
GCDCA+stool	FGF basic	GCDCA+stool-Creatinine+blood-L-Alanine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+16:0/18:0-PC+blood+18:0-LPC+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool+L-Tyrosine+stool+16:0/18:0-PC+blood+18:0-LPC+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool+L-Phenylalanine+stool-18:3n6+blood+Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool+L-Tyrosine+stool-18:3n6+blood+Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-Acetic acid+stool+18:3n6+blood+Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool+L-Tyrosine+stool+Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-Acetic acid+stool-Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool+L-Phenylalanine+stool-18:3n6+blood+L-Alanine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool+L-Tyrosine+stool-18:3n6+blood+L-Alanine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-Acetic acid+stool+18:3n6+blood+L-Alanine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-Propionic acid+stool-18:0/18:1-PC+blood+L-Alanine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	DM-LS
Odoribacter	FGF basic	Odoribacter-L-2-Aminobutyric acid+blood+TCA+blood+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-LS
Odoribacter	FGF basic	Odoribacter+DHA+blood-TCA+blood+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-LS
Odoribacter	FGF basic	Odoribacter-14:0/16:0-PC+blood+L-Alanine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-LS
Odoribacter	FGF basic	Odoribacter-d18:0-24:1-SM+blood+L-Alanine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-LS
Odoribacter	FGF basic	Odoribacter-14:0/16:0-PC+blood+Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-LS
Odoribacter	FGF basic	Odoribacter-14:0/16:0-PC+blood+16:0/18:2-PI+blood-FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	FGF basic	Isobutyric acid+stool+Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_scfa	serum_cytokines	0.408	0.65	no	no	no	no	no	no	DM-LS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-nutriCA+stool-Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool+L-Tyrosine+stool+Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-UDCA+stool-iso-LCA+blood-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-UDCA+stool+18:3n6+blood+Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool+L-Tyrosine+stool-18:3n6+blood+Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-UDCA+stool-L-Homocystine+blood-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-UDCA+stool-18:3n3+blood-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-nutriCA+stool-18:3n3+blood-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-UDCA+stool-16:0/18:0-PC+blood+18:0-LPC+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool+L-Tyrosine+stool+16:0/18:0-PC+blood+18:0-LPC+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-UDCA+stool+18:3n6+blood+L-Alanine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool+L-Tyrosine+stool-18:3n6+blood+L-Alanine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-nutriCA+stool-18:0+blood-GCA+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	DM-LS
Anaerostipes	FGF basic	Anaerostipes-Hepatitis B-FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-LS
Anaerostipes	FGF basic	Anaerostipes-Chronic myeloid leukemia-FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-LS
Anaerostipes	FGF basic	Anaerostipes-Insulin resistance-FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-LS
Anaerostipes	FGF basic	Anaerostipes-Prostate cancer-FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	DM-LS
TUDCA+stool	FGF basic	TUDCA+stool-UDCA+stool+18:3n6+blood+L-Alanine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-LS
TUDCA+stool	FGF basic	TUDCA+stool-UDCA+stool-iso-LCA+blood-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-LS
TUDCA+stool	FGF basic	TUDCA+stool-UDCA+stool+18:3n6+blood+Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-LS
TUDCA+stool	FGF basic	TUDCA+stool-UDCA+stool-L-Homocystine+blood-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-LS
TUDCA+stool	FGF basic	TUDCA+stool-UDCA+stool-18:3n3+blood-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-LS
TUDCA+stool	FGF basic	TUDCA+stool-UDCA+stool-16:0/18:0-PC+blood+18:0-LPC+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.241	0.65	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	FGF basic	Isovaleric acid+stool+Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_scfa	serum_cytokines	0.343	0.65	no	no	no	no	no	no	DM-LS
Paraprevotella	FGF basic	Paraprevotella+Glutathione metabolism+Adipocytokine signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.118	0.65	no	no	no	no	no	no	DM-LS
Paraprevotella	FGF basic	Paraprevotella-18:0/22:6-PA+blood-GCA+blood+FGF basic	Indirect	Genus	serum_cytokines	0.118	0.65	no	no	no	no	no	no	DM-LS
Paraprevotella	FGF basic	Paraprevotella+Glutathione metabolism-Prostate cancer-FGF basic	Indirect	Genus	serum_cytokines	0.118	0.65	no	no	no	no	no	no	DM-LS
Paraprevotella	FGF basic	Paraprevotella+Arachidonic acid metabolism-Prostate cancer-FGF basic	Indirect	Genus	serum_cytokines	0.118	0.65	no	no	no	no	no	no	DM-LS
Paraprevotella	FGF basic	Paraprevotella+Glutathione metabolism+Tight junction+FGF basic	Indirect	Genus	serum_cytokines	0.118	0.65	no	no	no	no	no	no	DM-LS
Paraprevotella	FGF basic	Paraprevotella+Arachidonic acid metabolism+Tight junction+FGF basic	Indirect	Genus	serum_cytokines	0.118	0.65	no	no	no	no	no	no	DM-LS
Paraprevotella	FGF basic	Paraprevotella+Glutathione metabolism-Transcriptional misregulation in cancer-FGF basic	Indirect	Genus	serum_cytokines	0.118	0.65	no	no	no	no	no	no	DM-LS
Paraprevotella	FGF basic	Paraprevotella+Arachidonic acid metabolism-Transcriptional misregulation in cancer-FGF basic	Indirect	Genus	serum_cytokines	0.118	0.65	no	no	no	no	no	no	DM-LS
Paraprevotella	FGF basic	Paraprevotella+Glutathione metabolism-Hepatitis B-FGF basic	Indirect	Genus	serum_cytokines	0.118	0.65	no	no	no	no	no	no	DM-LS
Paraprevotella	FGF basic	Paraprevotella+Arachidonic acid metabolism-Hepatitis B-FGF basic	Indirect	Genus	serum_cytokines	0.118	0.65	no	no	no	no	no	no	DM-LS
Paraprevotella	FGF basic	Paraprevotella+Glutathione metabolism-Insulin resistance-FGF basic	Indirect	Genus	serum_cytokines	0.118	0.65	no	no	no	no	no	no	DM-LS
Paraprevotella	FGF basic	Paraprevotella+Arachidonic acid metabolism-Insulin resistance-FGF basic	Indirect	Genus	serum_cytokines	0.118	0.65	no	no	no	no	no	no	DM-LS
iso-LCA+blood	FGF basic	iso-LCA+blood-Sarcosine+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.507	0.65	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	FGF basic	Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.785	0.65	no	no	no	no	no	no	DM-LS
Gemmiger	FGF basic	Gemmiger+DHA+blood-TCA+blood+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	DM-LS
GDCA+stool	FGF basic	GDCA+stool+18:0/18:1-PC+blood+L-Alanine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.656	0.65	no	no	no	no	no	no	DM-LS
Methanobrevibacter	FGF basic	Methanobrevibacter-Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.629	0.65	no	no	no	no	no	no	DM-LS
Methanobrevibacter	FGF basic	Methanobrevibacter+18:0-LPC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.629	0.65	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-18:3n6+blood+L-Alanine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool+16:0/18:0-PC+blood+18:0-LPC+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool+Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-18:3n6+blood+Sarcosine+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	DM-LS
CDCA+stool	FGF basic	CDCA+stool+18:3n6+blood+L-Alanine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.663	0.65	no	no	no	no	no	no	DM-LS
CDCA+stool	FGF basic	CDCA+stool-iso-LCA+stool-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.663	0.65	no	no	no	no	no	no	DM-LS
CDCA+stool	FGF basic	CDCA+stool-iso-LCA+blood-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.663	0.65	no	no	no	no	no	no	DM-LS
CDCA+stool	FGF basic	CDCA+stool-Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.663	0.65	no	no	no	no	no	no	DM-LS
CDCA+stool	FGF basic	CDCA+stool+18:3n6+blood+Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.663	0.65	no	no	no	no	no	no	DM-LS
CA+stool	FGF basic	CA+stool-Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.827	0.65	no	no	no	no	no	no	DM-LS
CA+stool	FGF basic	CA+stool+18:3n6+blood+Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.827	0.65	no	no	no	no	no	no	DM-LS
CA+stool	FGF basic	CA+stool-iso-LCA+stool-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.827	0.65	no	no	no	no	no	no	DM-LS
CA+stool	FGF basic	CA+stool+18:3n6+blood+L-Alanine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.827	0.65	no	no	no	no	no	no	DM-LS
Slackia	FGF basic	Slackia+Primary immunodeficiency+FGF basic	Indirect	Genus	serum_cytokines	0.94	0.65	no	no	no	no	no	no	DM-LS
HDCA+blood	FGF basic	HDCA+blood-Sarcosine+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.483	0.65	no	no	no	no	no	no	DM-LS
UDCA+stool	FGF basic	UDCA+stool+18:3n6+blood+L-Alanine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.266	0.65	no	no	no	no	no	no	DM-LS
UDCA+stool	FGF basic	UDCA+stool-iso-LCA+blood-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.266	0.65	no	no	no	no	no	no	DM-LS
UDCA+stool	FGF basic	UDCA+stool+18:3n6+blood+Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.266	0.65	no	no	no	no	no	no	DM-LS
UDCA+stool	FGF basic	UDCA+stool-L-Homocystine+blood-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.266	0.65	no	no	no	no	no	no	DM-LS
UDCA+stool	FGF basic	UDCA+stool-18:3n3+blood-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.266	0.65	no	no	no	no	no	no	DM-LS
UDCA+stool	FGF basic	UDCA+stool-16:0/18:0-PC+blood+18:0-LPC+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.266	0.65	no	no	no	no	no	no	DM-LS
TDCA+stool	FGF basic	TDCA+stool+UDCA+stool+18:3n6+blood+L-Alanine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.963	0.65	no	no	no	no	no	no	DM-LS
TDCA+stool	FGF basic	TDCA+stool+UDCA+stool-iso-LCA+blood-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.963	0.65	no	no	no	no	no	no	DM-LS
TDCA+stool	FGF basic	TDCA+stool+UDCA+stool+18:3n6+blood+Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.963	0.65	no	no	no	no	no	no	DM-LS
TDCA+stool	FGF basic	TDCA+stool+UDCA+stool-L-Homocystine+blood-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.963	0.65	no	no	no	no	no	no	DM-LS
TDCA+stool	FGF basic	TDCA+stool+UDCA+stool-18:3n3+blood-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.963	0.65	no	no	no	no	no	no	DM-LS
TDCA+stool	FGF basic	TDCA+stool+UDCA+stool-16:0/18:0-PC+blood+18:0-LPC+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.963	0.65	no	no	no	no	no	no	DM-LS
nutriCA+stool	FGF basic	nutriCA+stool-Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.481	0.65	no	no	no	no	no	no	DM-LS
nutriCA+stool	FGF basic	nutriCA+stool-18:3n3+blood-Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.481	0.65	no	no	no	no	no	no	DM-LS
nutriCA+stool	FGF basic	nutriCA+stool-18:0+blood-GCA+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.481	0.65	no	no	no	no	no	no	DM-LS
GDCA+blood	FGF basic	GDCA+blood+iso-LCA+blood-Sarcosine+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.632	0.65	no	no	no	no	no	no	DM-LS
acetic acid C2+blood	FGF basic	acetic acid C2+blood-L-Alanine+blood-FGF basic	Indirect	serum_scfa	serum_cytokines	0.000193	0.65	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	FGF basic	acetic acid C2+blood-Sarcosine+blood-FGF basic	Indirect	serum_scfa	serum_cytokines	0.000193	0.65	up	dn	no	no	no	no	DM-LS
Adlercreutzia	FGF basic	Adlercreutzia+18:0-LPC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.548	0.65	no	no	no	no	no	no	DM-LS
Clostridium	FGF basic	Clostridium+cGMP-PKG signaling pathway+C-type lectin receptor signaling pathway-FGF basic	Indirect	Genus	serum_cytokines	0.925	0.65	no	no	no	no	no	no	DM-LS
Clostridium	FGF basic	Clostridium-14:0/16:0-PC+blood+Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.925	0.65	no	no	no	no	no	no	DM-LS
Clostridium	FGF basic	Clostridium-14:0/16:0-PC+blood+16:0/18:2-PI+blood-FGF basic	Indirect	Genus	serum_cytokines	0.925	0.65	no	no	no	no	no	no	DM-LS
Clostridium	FGF basic	Clostridium-14:0/18:2-PC+blood+16:0/18:2-PI+blood-FGF basic	Indirect	Genus	serum_cytokines	0.925	0.65	no	no	no	no	no	no	DM-LS
Clostridium	FGF basic	Clostridium-14:0/16:0-PC+blood+L-Alanine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.925	0.65	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	FGF basic	T-¦Á-MCA+stool-TCA+stool+18:0/18:1-PC+blood+L-Alanine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.48	0.65	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	FGF basic	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.48	0.65	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	FGF basic	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+Sarcosine+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.48	0.65	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	FGF basic	12-ketoDCA+blood-20:3-LPE+blood+Sarcosine+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.517	0.65	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	FGF basic	12-ketoDCA+blood+GLCA+blood-Sarcosine+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.517	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus+Phagosome+Bacterial invasion of epithelial cells+FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus+Phagosome+Arrhythmogenic right ventricular cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus+Phagosome-Chemical carcinogenesis - receptor activation-FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus+Phagosome+Hypertrophic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus+Phagosome+Tight junction+FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus+Cell adhesion molecules+Leukocyte transendothelial migration+FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus+Phagosome+Leukocyte transendothelial migration+FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus-Phenylacetic acid+stool-Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus+Allograft rejection+Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus+Type I diabetes mellitus+Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus+Graft-versus-host disease+Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus+Autoimmune thyroid disease+Sarcosine+blood-FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus+Cell adhesion molecules+Salmonella infection+FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus+Phagosome+Salmonella infection+FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus+Cell adhesion molecules+Rheumatoid arthritis+FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus+Type I diabetes mellitus+Rheumatoid arthritis+FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus+Phagosome+Rheumatoid arthritis+FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Butyricicoccus	FGF basic	Butyricicoccus+Autoimmune thyroid disease+Rheumatoid arthritis+FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	DM-LS
Blautia	IL-6	Blautia-20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	DM-LS
Parabacteroides	IL-6	Parabacteroides-Glucagon signaling pathway+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	4.19E-05	0.52	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-6	Parabacteroides-Spliceosome+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	4.19E-05	0.52	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-6	Parabacteroides+Choline+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	4.19E-05	0.52	no	up	up	no	no	no	DM-LS
Dorea	IL-6	Dorea-Lipid and atherosclerosis-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	DM-LS
Faecalibacterium	IL-6	Faecalibacterium-Cysteine+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.0039	0.52	no	dn	dn	no	no	no	DM-LS
TUDCA+blood	IL-6	TUDCA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.0282	0.52	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	IL-6	isocapric acid iso-C6+blood-n3+blood-Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.0458	0.52	no	no	dn	no	no	no	DM-LS
Bacteroides	IL-6	Bacteroides+n3+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.000267	0.52	dn	dn	up	no	no	no	DM-LS
Bacteroides	IL-6	Bacteroides+22:6n3+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.000267	0.52	dn	dn	up	no	no	no	DM-LS
Propionic acid+stool	IL-6	Propionic acid+stool-UFA%+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.0436	0.52	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IL-6	Propionic acid+stool-MUFA%+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.0436	0.52	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IL-6	Propionic acid+stool-ACA+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.0436	0.52	dn	no	up	no	no	no	DM-LS
[Ruminococcus]	IL-6	[Ruminococcus]-UFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.0679	0.52	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	IL-6	[Ruminococcus]-20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.0679	0.52	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	IL-6	[Ruminococcus]-MUFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.0679	0.52	no	no	dn	no	no	no	DM-LS
GUDCA+blood	IL-6	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.0766	0.52	no	no	dn	no	no	no	DM-LS
Acetic acid+stool	IL-6	Acetic acid+stool-UFA%+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.0656	0.52	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	IL-6	Acetic acid+stool-Cysteine+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.0656	0.52	dn	no	no	no	no	no	DM-LS
Alistipes	IL-6	Alistipes-L-Arginine+blood+UFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	DM-LS
Alistipes	IL-6	Alistipes-HIF-1 signaling pathway+Measles-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	DM-LS
Alistipes	IL-6	Alistipes-L-Aspartic acid+blood+n3+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	DM-LS
Butyricimonas	IL-6	Butyricimonas+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	DM-LS
Collinsella	IL-6	Collinsella-Signaling pathways regulating pluripotency of stem cells+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-LS
Collinsella	IL-6	Collinsella-Colorectal cancer+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-LS
Collinsella	IL-6	Collinsella-Glioma+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-LS
Collinsella	IL-6	Collinsella-Long-term potentiation+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-LS
Collinsella	IL-6	Collinsella-Choline metabolism in cancer+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-LS
Collinsella	IL-6	Collinsella-Gastric cancer+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-LS
Collinsella	IL-6	Collinsella-ErbB signaling pathway+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-LS
Collinsella	IL-6	Collinsella-Phosphatidylinositol signaling system+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	IL-6	total_blood_scfa+blood+TUDCA+blood+Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.168	0.52	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-6	[Eubacterium]-Viral myocarditis-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.0692	0.52	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-6	[Eubacterium]-Pathogenic Escherichia coli infection-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.0692	0.52	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-6	[Eubacterium]-Phagosome-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.0692	0.52	no	no	no	no	no	no	DM-LS
LCA+stool	IL-6	LCA+stool-ACA+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.314	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia+Apoptosis-Cushing syndrome+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia+LCA+stool-ACA+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia-4-hydroxybenzoic acid+stool+ACA+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia+Apoptosis+Viral myocarditis-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia+Apoptosis-Glucagon signaling pathway+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia+Apoptosis+Fc gamma R-mediated phagocytosis-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia+Apoptosis-Inflammatory mediator regulation of TRP channels+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia-18:0/18:2-PI+blood-Creatinine+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia+Apoptosis+IL-17 signaling pathway-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia-18:0/18:2-PI+blood-TUDCA+blood+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia+Apoptosis+Neutrophil extracellular trap formation-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia+Apoptosis-Melanogenesis+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia-Retrograde endocannabinoid signaling-20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia+Apoptosis-Long-term potentiation+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia+Apoptosis+Lipid and atherosclerosis-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia+Apoptosis+Pathogenic Escherichia coli infection-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia+Apoptosis+Systemic lupus erythematosus-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia-Retrograde endocannabinoid signaling+CA+blood+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia+Apoptosis+Staphylococcus aureus infection-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia+Apoptosis-Aldosterone synthesis and secretion+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Akkermansia	IL-6	Akkermansia+Apoptosis-Adrenergic signaling in cardiomyocytes+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	DM-LS
Bifidobacterium	IL-6	Bifidobacterium+Chemical carcinogenesis - receptor activation+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.105	0.52	no	dn	no	no	no	no	DM-LS
Ruminococcus	IL-6	Ruminococcus+Type I diabetes mellitus-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.335	0.52	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-6	Ruminococcus+Endocytosis-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.335	0.52	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-6	Ruminococcus+Allograft rejection-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.335	0.52	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-6	Ruminococcus+22:6n3+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.335	0.52	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-6	Ruminococcus+Graft-versus-host disease-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.335	0.52	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-6	Ruminococcus+Phagosome-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.335	0.52	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-6	Ruminococcus+Cell adhesion molecules-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.335	0.52	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-6	Ruminococcus+Autoimmune thyroid disease-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.335	0.52	no	no	no	no	no	no	DM-LS
GCDCA+blood	IL-6	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.31	0.52	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-6	Succinivibrio-L-Phenylalanine+stool+n3+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.138	0.52	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-6	Succinivibrio-Phospholipase D signaling pathway+Cushing syndrome+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.138	0.52	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-6	Succinivibrio-Phospholipase D signaling pathway-MUFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.138	0.52	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-6	Succinivibrio-L-Phenylalanine+stool+Cysteine+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.138	0.52	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-6	Succinivibrio-Phospholipase D signaling pathway+Chemical carcinogenesis - receptor activation+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.138	0.52	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-6	Succinivibrio-L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.138	0.52	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-6	Succinivibrio-L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.138	0.52	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-6	Succinivibrio-Phospholipase D signaling pathway-UFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.138	0.52	no	no	no	no	no	no	DM-LS
ACA+blood	IL-6	ACA+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.338	0.52	no	no	no	no	no	no	DM-LS
DCA+stool	IL-6	DCA+stool-UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.195	0.52	no	no	no	no	no	no	DM-LS
DCA+stool	IL-6	DCA+stool-ACA+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.195	0.52	no	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-6	Butyric acid+stool+Propionic acid+stool-MUFA%+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.102	0.52	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-6	Butyric acid+stool+8-HETE+blood-ACA+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.102	0.52	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-6	Butyric acid+stool+Propionic acid+stool-ACA+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.102	0.52	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-6	Butyric acid+stool-16:1/16:1-PC+blood+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.102	0.52	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-6	Butyric acid+stool+AA+blood+Choline+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.102	0.52	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-6	Butyric acid+stool+Propionic acid+stool-UFA%+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.102	0.52	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-6	Butyric acid+stool-Phenylacetic acid+stool+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.102	0.52	dn	no	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	IL-6	4-hydroxybenzoic acid+stool+ACA+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.52	no	dn	no	no	no	no	DM-LS
GCA+blood	IL-6	GCA+blood+TCA+blood+TUDCA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.16	0.52	no	no	no	no	no	no	DM-LS
ACA+stool	IL-6	ACA+stool+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.417	0.52	no	no	no	no	no	no	DM-LS
ACA+stool	IL-6	ACA+stool+20:2+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.417	0.52	no	no	no	no	no	no	DM-LS
CDCA+blood	IL-6	CDCA+blood-MUFA%+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.506	0.52	no	no	no	no	no	no	DM-LS
CDCA+blood	IL-6	CDCA+blood-Cysteine+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.506	0.52	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-6	capric acid C6+blood+UFA%+blood-Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.433	0.52	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-6	capric acid C6+blood+TUDCA+blood+Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.433	0.52	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-6	capric acid C6+blood+MUFA%+blood-Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.433	0.52	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-6	Pyramidobacter-Carbon metabolism-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.45	0.52	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-6	Pyramidobacter+Glucagon signaling pathway+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.45	0.52	no	no	no	no	no	no	DM-LS
Prevotella	IL-6	Prevotella+Aldosterone synthesis and secretion+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	DM-LS
Prevotella	IL-6	Prevotella+Adrenergic signaling in cardiomyocytes+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	DM-LS
Prevotella	IL-6	Prevotella+Chemical carcinogenesis - receptor activation+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	DM-LS
Prevotella	IL-6	Prevotella+Inflammatory mediator regulation of TRP channels+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	DM-LS
Prevotella	IL-6	Prevotella-Carbon metabolism-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	DM-LS
Prevotella	IL-6	Prevotella+Amphetamine addiction+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	DM-LS
Prevotella	IL-6	Prevotella+Dopaminergic synapse+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	DM-LS
Prevotella	IL-6	Prevotella+Cushing syndrome+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	DM-LS
Prevotella	IL-6	Prevotella+Melanogenesis+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	DM-LS
TCA+blood	IL-6	TCA+blood+TUDCA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.339	0.52	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-6	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.38	0.52	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-6	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.38	0.52	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-6	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.38	0.52	no	no	no	no	no	no	DM-LS
HCA+stool	IL-6	HCA+stool-Cysteine+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.155	0.52	no	no	no	no	no	no	DM-LS
Roseburia	IL-6	Roseburia-20:2+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.495	0.52	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	IL-6	12-ketoDCA+stool+DCA+stool-ACA+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.505	0.52	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	IL-6	12-ketoDCA+stool+LCA+stool-ACA+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.505	0.52	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	IL-6	12-ketoDCA+stool+18:0/18:1-PE+blood-ACA+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.505	0.52	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	IL-6	12-ketoDCA+stool+DCA+stool-UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.505	0.52	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	IL-6	12-ketoDCA+stool-Glycine+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.505	0.52	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	IL-6	12-ketoDCA+stool+18:0/18:1-PE+blood-UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.505	0.52	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	IL-6	12-ketoDCA+stool-Glycine+blood+MUFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.505	0.52	no	no	no	no	no	no	DM-LS
GLCA+blood	IL-6	GLCA+blood-PUFA/MUFA+blood+UFA%+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.319	0.52	no	no	no	no	no	no	DM-LS
GLCA+blood	IL-6	GLCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.319	0.52	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	IL-6	L-Tryptophan+stool+n3+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.557	0.52	no	no	no	no	no	no	DM-LS
CA+blood	IL-6	CA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.606	0.52	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IL-6	L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.398	0.52	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IL-6	L-Phenylalanine+stool+n3+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.398	0.52	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IL-6	L-Phenylalanine+stool+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.398	0.52	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	IL-6	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.407	0.52	no	no	no	no	no	no	DM-LS
GCA+stool	IL-6	GCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-LS
GCA+stool	IL-6	GCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-LS
GCA+stool	IL-6	GCA+stool+nutriCA+stool+CA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-LS
GCA+stool	IL-6	GCA+stool+GCDCA+stool+CA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-LS
GCA+stool	IL-6	GCA+stool+nutriCA+stool-n3+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-LS
GCA+stool	IL-6	GCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-LS
GCA+stool	IL-6	GCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-LS
GCA+stool	IL-6	GCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-LS
GCA+stool	IL-6	GCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-LS
GCA+stool	IL-6	GCA+stool+GCDCA+stool-Creatinine+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-LS
GCA+stool	IL-6	GCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-LS
GCA+stool	IL-6	GCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	IL-6	T-a-MCA+blood+UFA%+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.478	0.52	no	no	no	no	no	no	DM-LS
Coprococcus	IL-6	Coprococcus-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	DM-LS
Oscillospira	IL-6	Oscillospira-Adrenergic signaling in cardiomyocytes+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.62	0.52	no	no	no	no	no	no	DM-LS
Oscillospira	IL-6	Oscillospira+Peroxisome-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.62	0.52	no	no	no	no	no	no	DM-LS
HCA+blood	IL-6	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.544	0.52	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-6	iso-LCA+stool-CDCA+blood-Cysteine+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-6	iso-LCA+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-6	iso-LCA+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-6	iso-LCA+stool-18:3n6+blood-20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-6	iso-LCA+stool-nutriCA+stool+CA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-6	iso-LCA+stool-18:3n6+blood-UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-6	iso-LCA+stool-Glycine+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-6	iso-LCA+stool-nutriCA+stool-n3+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-6	iso-LCA+stool-18:1-LPE+blood-n3+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-6	iso-LCA+stool-Sarcosine+blood-TUDCA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-6	iso-LCA+stool-18:1-LPE+blood-22:6n3+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-6	iso-LCA+stool-CDCA+blood-MUFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-6	iso-LCA+stool-Glycine+blood+MUFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-6	iso-LCA+stool+LCA+stool-ACA+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	IL-6	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.262	0.52	no	no	no	no	no	no	DM-LS
DCA+blood	IL-6	DCA+blood-MUFA%+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.122	0.52	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-6	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.33	0.52	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-6	3-(3-Hydroxyphenyl)propanoic acid+stool-T-a-MCA+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.33	0.52	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-6	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.33	0.52	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-6	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood-UFA%+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.33	0.52	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-6	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2/16:0-PC+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.33	0.52	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-6	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.33	0.52	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-6	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood-MUFA%+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.33	0.52	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-6	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.33	0.52	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-6	3-(3-Hydroxyphenyl)propanoic acid+stool+UDCA+stool-20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.33	0.52	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-6	3-(3-Hydroxyphenyl)propanoic acid+stool-16:0/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.33	0.52	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-6	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.33	0.52	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-6	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.33	0.52	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-6	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2n6c+blood+20:2+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.33	0.52	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IL-6	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.304	0.52	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IL-6	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.304	0.52	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IL-6	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.304	0.52	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IL-6	Indole-3-Acetic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.304	0.52	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IL-6	Indole-3-Acetic acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.304	0.52	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IL-6	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.304	0.52	no	no	no	no	no	no	DM-LS
TCA+stool	IL-6	TCA+stool-16:0/20:5-PC+blood+n3+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-LS
TCA+stool	IL-6	TCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-LS
TCA+stool	IL-6	TCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-LS
TCA+stool	IL-6	TCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-LS
TCA+stool	IL-6	TCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-LS
TCA+stool	IL-6	TCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-LS
TCA+stool	IL-6	TCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-LS
TCA+stool	IL-6	TCA+stool-16:0/20:5-PC+blood-MUFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-LS
TCA+stool	IL-6	TCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-LS
TCA+stool	IL-6	TCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-LS
TCA+stool	IL-6	TCA+stool+18:1/18:1-PC+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-LS
TCA+stool	IL-6	TCA+stool+16:0/20:3-PC+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-LS
TCA+stool	IL-6	TCA+stool-16:0/20:5-PC+blood-20:2+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-LS
TCA+stool	IL-6	TCA+stool+18:1/18:1-PC+blood+20:2+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-LS
TCA+stool	IL-6	TCA+stool+16:0/20:3-PC+blood+20:2+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-LS
TCA+stool	IL-6	TCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-LS
TCA+stool	IL-6	TCA+stool-16:0/20:5-PC+blood+CA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-6	HDCA+stool-18:1/20:3-PC+blood-CA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-6	HDCA+stool-nutriCA+stool+CA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-6	HDCA+stool+LCA+stool-ACA+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-6	HDCA+stool-18:1-LPE+blood-22:6n3+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-6	HDCA+stool-18:1/20:3-PC+blood+20:2+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-6	HDCA+stool-18:1-LPC+blood+20:2+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-6	HDCA+stool-16:0/20:3-PC+blood+20:2+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-6	HDCA+stool-18:1/18:1-PC+blood+20:2+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-6	HDCA+stool+EPA+blood+n3+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-6	HDCA+stool-nutriCA+stool-n3+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-6	HDCA+stool-18:1-LPE+blood-n3+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-6	HDCA+stool-16:0/20:3-PC+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-6	HDCA+stool-18:1/18:1-PC+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	DM-LS
Lachnospira	IL-6	Lachnospira+Choline+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	DM-LS
Fusobacterium	IL-6	Fusobacterium+UFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.628	0.52	no	no	no	no	no	no	DM-LS
Fusobacterium	IL-6	Fusobacterium+MUFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.628	0.52	no	no	no	no	no	no	DM-LS
isobutyric acid C4+blood	IL-6	isobutyric acid C4+blood+MUFA%+blood-Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.0151	0.52	up	up	no	no	no	no	DM-LS
GCDCA+stool	IL-6	GCDCA+stool-Creatinine+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IL-6	GCDCA+stool+CA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-Acetic acid+stool-Cysteine+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-Propionic acid+stool-ACA+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+n3+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-Propionic acid+stool-MUFA%+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-Propionic acid+stool-UFA%+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-Acetic acid+stool-UFA%+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	DM-LS
Odoribacter	IL-6	Odoribacter+Choline+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-6	Isobutyric acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.408	0.52	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-6	Isobutyric acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.408	0.52	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-6	Isobutyric acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.408	0.52	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-6	Isobutyric acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.408	0.52	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-6	Isobutyric acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.408	0.52	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-6	Isobutyric acid+stool-nutriCA+stool+CA+blood+Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.408	0.52	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-6	Isobutyric acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.408	0.52	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-6	Isobutyric acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.408	0.52	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-6	Isobutyric acid+stool-nutriCA+stool-n3+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.408	0.52	no	no	no	no	no	no	DM-LS
Lachnobacterium	IL-6	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.867	0.52	no	no	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-6	Kynurenic acid+stool-nutriCA+stool+CA+blood+Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.037	0.52	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-6	Kynurenic acid+stool-nutriCA+stool-n3+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.037	0.52	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-6	Kynurenic acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.037	0.52	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-6	Kynurenic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.037	0.52	dn	dn	no	no	no	no	DM-LS
Anaerostipes	IL-6	Anaerostipes-Non-small cell lung cancer+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.568	0.52	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-6	Anaerostipes+TUDCA+blood+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.568	0.52	no	no	no	no	no	no	DM-LS
TUDCA+stool	IL-6	TUDCA+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.241	0.52	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-6	Isovaleric acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.343	0.52	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-6	Isovaleric acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.343	0.52	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-6	Isovaleric acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.343	0.52	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-6	Isovaleric acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.343	0.52	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-6	Isovaleric acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.343	0.52	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-6	Isovaleric acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.343	0.52	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-6	Isovaleric acid+stool-nutriCA+stool-n3+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.343	0.52	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-6	Isovaleric acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.343	0.52	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-6	Isovaleric acid+stool-nutriCA+stool+CA+blood+Eotaxin-IL-6	Indirect	stool_scfa	serum_cytokines	0.343	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Arachidonic acid metabolism+Biosynthesis of amino acids-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Betaine+blood+UFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Glutathione metabolism-Choline metabolism in cancer+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Arachidonic acid metabolism-Choline metabolism in cancer+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Glutathione metabolism-Cholinergic synapse+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Glutathione metabolism-mRNA surveillance pathway+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Arachidonic acid metabolism-mRNA surveillance pathway+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Glutathione metabolism-Non-small cell lung cancer+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Arachidonic acid metabolism-Non-small cell lung cancer+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+18:0/20:2-PC+blood+20:2+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Glutathione metabolism-Colorectal cancer+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Arachidonic acid metabolism-Colorectal cancer+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Arachidonic acid metabolism-Cell cycle+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Arachidonic acid metabolism+Choline+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Glutathione metabolism-ErbB signaling pathway+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Arachidonic acid metabolism-ErbB signaling pathway+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Glutathione metabolism-Phosphatidylinositol signaling system+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Arachidonic acid metabolism-Phosphatidylinositol signaling system+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella-18:0/22:6-PA+blood+22:6n3+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Glutathione metabolism-Gastric cancer+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Arachidonic acid metabolism-Gastric cancer+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Glutathione metabolism-Glioma+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Arachidonic acid metabolism-Glioma+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Glutathione metabolism-Signaling pathways regulating pluripotency of stem cells+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Arachidonic acid metabolism-Signaling pathways regulating pluripotency of stem cells+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Glutathione metabolism-Spliceosome+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Arachidonic acid metabolism-Spliceosome+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Betaine+blood-CA+blood+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Glutathione metabolism-Long-term potentiation+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-6	Paraprevotella+Arachidonic acid metabolism-Long-term potentiation+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	DM-LS
iso-LCA+blood	IL-6	iso-LCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.507	0.52	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	IL-6	Phenylacetic acid+stool+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.785	0.52	no	no	no	no	no	no	DM-LS
Gemmiger	IL-6	Gemmiger-18:1-LPC+blood+20:2+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	DM-LS
Gemmiger	IL-6	Gemmiger+L-Phenylalanine+blood+n3+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-6	GDCA+stool-L-Phenylalanine+blood+n3+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-6	GDCA+stool-L-Isoleucine+blood+n3+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-6	GDCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-6	GDCA+stool-L-Histidine+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-6	GDCA+stool+20:3/18:0-PC+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-6	GDCA+stool-L-Isoleucine+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-6	GDCA+stool+Glycine+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-6	GDCA+stool+24:1+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-6	GDCA+stool-Propionic acid+stool-UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-6	GDCA+stool-L-Histidine+blood+MUFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-6	GDCA+stool+Glycine+blood+MUFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-6	GDCA+stool-Propionic acid+stool-MUFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-6	GDCA+stool+20:3/18:0-PC+blood+ACA+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-6	GDCA+stool+24:1+blood+ACA+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-6	GDCA+stool-Propionic acid+stool-ACA+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-6	GDCA+stool+20:3/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IL-6	Methanobrevibacter+n3+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.629	0.52	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	IL-6	L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_cometabolism	serum_cytokines	0.44	0.52	no	no	no	no	no	no	DM-LS
CDCA+stool	IL-6	CDCA+stool-20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.663	0.52	no	no	no	no	no	no	DM-LS
CA+stool	IL-6	CA+stool+CA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.827	0.52	no	no	no	no	no	no	DM-LS
Slackia	IL-6	Slackia+Platinum drug resistance+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.94	0.52	no	no	no	no	no	no	DM-LS
Slackia	IL-6	Slackia-Neutrophil extracellular trap formation-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.94	0.52	no	no	no	no	no	no	DM-LS
Slackia	IL-6	Slackia-Cysteine+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.94	0.52	no	no	no	no	no	no	DM-LS
HDCA+blood	IL-6	HDCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.483	0.52	no	no	no	no	no	no	DM-LS
UDCA+stool	IL-6	UDCA+stool-20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.266	0.52	no	no	no	no	no	no	DM-LS
TDCA+stool	IL-6	TDCA+stool+UDCA+stool-20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.963	0.52	no	no	no	no	no	no	DM-LS
nutriCA+stool	IL-6	nutriCA+stool+CA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.481	0.52	no	no	no	no	no	no	DM-LS
nutriCA+stool	IL-6	nutriCA+stool-n3+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.481	0.52	no	no	no	no	no	no	DM-LS
GDCA+blood	IL-6	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.632	0.52	no	no	no	no	no	no	DM-LS
acetic acid C2+blood	IL-6	acetic acid C2+blood+total_blood_scfa+blood+TUDCA+blood+Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.000193	0.52	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	IL-6	acetic acid C2+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.000193	0.52	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	IL-6	acetic acid C2+blood+capric acid C6+blood+TUDCA+blood+Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.000193	0.52	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	IL-6	acetic acid C2+blood+capric acid C6+blood+MUFA%+blood-Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.000193	0.52	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	IL-6	acetic acid C2+blood-d18:1-14:1-SM+blood-MUFA%+blood-Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.000193	0.52	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	IL-6	acetic acid C2+blood+capric acid C6+blood+UFA%+blood-Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.000193	0.52	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	IL-6	acetic acid C2+blood-d18:1-14:1-SM+blood-UFA%+blood-Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.000193	0.52	up	dn	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	IL-6	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-IL-6	Indirect	serum_scfa	serum_cytokines	0.117	0.52	no	no	no	no	no	no	DM-LS
Adlercreutzia	IL-6	Adlercreutzia-16:0/20:5-PC+blood-20:2+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.548	0.52	no	no	no	no	no	no	DM-LS
Adlercreutzia	IL-6	Adlercreutzia+18:1-LPC+blood+20:2+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.548	0.52	no	no	no	no	no	no	DM-LS
Adlercreutzia	IL-6	Adlercreutzia-EPA+blood+n3+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.548	0.52	no	no	no	no	no	no	DM-LS
Adlercreutzia	IL-6	Adlercreutzia-16:0/20:5-PC+blood+n3+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.548	0.52	no	no	no	no	no	no	DM-LS
Adlercreutzia	IL-6	Adlercreutzia-16:0/20:5-PC+blood+CA+blood+Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.548	0.52	no	no	no	no	no	no	DM-LS
Adlercreutzia	IL-6	Adlercreutzia-16:0/20:5-PC+blood-MUFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.548	0.52	no	no	no	no	no	no	DM-LS
Adlercreutzia	IL-6	Adlercreutzia+16:0/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.548	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium+cGMP-PKG signaling pathway+Lipid and atherosclerosis-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium+cGMP-PKG signaling pathway+Endocytosis-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium+cGMP-PKG signaling pathway+IL-17 signaling pathway-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium+PUFA/MUFA+blood+UFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium-14:0/20:4-PC+blood-UFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium-Acetic acid+stool-UFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
 Clostridium	IL-6	Clostridium+Acetic acid+stool-UFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	NA	0.52	NA	NA	NA	no	no	no	DM-LS
Clostridium	IL-6	Clostridium-Acetic acid+stool-UFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
 Clostridium	IL-6	Clostridium+Acetic acid+stool-UFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	NA	0.52	NA	NA	NA	no	no	no	DM-LS
Clostridium	IL-6	Clostridium+cGMP-PKG signaling pathway+Fc gamma R-mediated phagocytosis-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium+cGMP-PKG signaling pathway+Neutrophil extracellular trap formation-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium+cGMP-PKG signaling pathway+Pathogenic Escherichia coli infection-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium-18:0/20:2-PC+blood+20:2+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium+CDCA+blood-Cysteine+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium-14:0/20:4-PC+blood-Cysteine+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium-Acetic acid+stool-Cysteine+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
 Clostridium	IL-6	Clostridium+Acetic acid+stool-Cysteine+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	NA	0.52	NA	NA	NA	no	no	no	DM-LS
Clostridium	IL-6	Clostridium-Acetic acid+stool-Cysteine+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
 Clostridium	IL-6	Clostridium+Acetic acid+stool-Cysteine+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	NA	0.52	NA	NA	NA	no	no	no	DM-LS
Clostridium	IL-6	Clostridium-14:0/20:4-PC+blood-Creatinine+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium-14:0/18:2-PC+blood-Creatinine+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium-14:0/20:4-PC+blood-20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium+CDCA+blood-MUFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium-14:0/20:4-PC+blood-MUFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium+cGMP-PKG signaling pathway+MUFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
Clostridium	IL-6	Clostridium-14:0/18:2-PC+blood-MUFA%+blood-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+n3+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood-MUFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+UFA%+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood-20:2+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+20:2+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+20:2+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-TCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-6	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+CA+blood+Eotaxin-IL-6	Indirect	stool_bileacids	serum_cytokines	0.48	0.52	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-8-HETE+blood-ACA+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-20:3-LPE+blood-22:6n3+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-20:3-LPE+blood+Choline+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-L-Lysine+blood+UFA%+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-L-Arginine+blood+UFA%+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-20:3-LPE+blood-n3+blood-Eotaxin-IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-6	Butyricicoccus+Allograft rejection-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.852	0.52	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-6	Butyricicoccus+Viral myocarditis-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.852	0.52	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-6	Butyricicoccus+Cell adhesion molecules-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.852	0.52	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-6	Butyricicoccus+Type I diabetes mellitus-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.852	0.52	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-6	Butyricicoccus+Graft-versus-host disease-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.852	0.52	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-6	Butyricicoccus+Phagosome-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.852	0.52	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-6	Butyricicoccus+Autoimmune thyroid disease-Eotaxin-IL-6	Indirect	Genus	serum_cytokines	0.852	0.52	no	no	no	no	no	no	DM-LS
Blautia	IL-13	Blautia-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	1.36E-05	0.00264	up	dn	dn	up	up	no	DM-LS
Parabacteroides	IL-13	Parabacteroides-Glucagon signaling pathway+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	4.19E-05	0.00264	no	up	up	up	up	no	DM-LS
Parabacteroides	IL-13	Parabacteroides-Spliceosome+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	4.19E-05	0.00264	no	up	up	up	up	no	DM-LS
Parabacteroides	IL-13	Parabacteroides+Choline+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	4.19E-05	0.00264	no	up	up	up	up	no	DM-LS
Dorea	IL-13	Dorea-Lipid and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	DM-LS
Faecalibacterium	IL-13	Faecalibacterium-Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0039	0.00264	no	dn	dn	up	up	no	DM-LS
TUDCA+blood	IL-13	TUDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.0282	0.00264	no	no	dn	up	up	no	DM-LS
isocapric acid iso-C6+blood	IL-13	isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.0458	0.00264	no	no	dn	up	up	no	DM-LS
Bacteroides	IL-13	Bacteroides+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-LS
Bacteroides	IL-13	Bacteroides+22:6n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	DM-LS
Propionic acid+stool	IL-13	Propionic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.0436	0.00264	dn	no	up	up	up	no	DM-LS
Propionic acid+stool	IL-13	Propionic acid+stool-MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.0436	0.00264	dn	no	up	up	up	no	DM-LS
Propionic acid+stool	IL-13	Propionic acid+stool-ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.0436	0.00264	dn	no	up	up	up	no	DM-LS
[Ruminococcus]	IL-13	[Ruminococcus]-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0679	0.00264	no	no	dn	up	up	no	DM-LS
[Ruminococcus]	IL-13	[Ruminococcus]-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0679	0.00264	no	no	dn	up	up	no	DM-LS
[Ruminococcus]	IL-13	[Ruminococcus]-MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0679	0.00264	no	no	dn	up	up	no	DM-LS
GUDCA+blood	IL-13	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00264	no	no	dn	up	up	no	DM-LS
Acetic acid+stool	IL-13	Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.0656	0.00264	dn	no	no	up	up	no	DM-LS
Acetic acid+stool	IL-13	Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.0656	0.00264	dn	no	no	up	up	no	DM-LS
Alistipes	IL-13	Alistipes-L-Arginine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	DM-LS
Alistipes	IL-13	Alistipes-HIF-1 signaling pathway+Measles-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	DM-LS
Alistipes	IL-13	Alistipes-L-Aspartic acid+blood+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	DM-LS
Butyricimonas	IL-13	Butyricimonas+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.17	0.00264	no	no	no	up	up	no	DM-LS
Collinsella	IL-13	Collinsella-Signaling pathways regulating pluripotency of stem cells+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-LS
Collinsella	IL-13	Collinsella-Colorectal cancer+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-LS
Collinsella	IL-13	Collinsella-Glioma+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-LS
Collinsella	IL-13	Collinsella-Long-term potentiation+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-LS
Collinsella	IL-13	Collinsella-Choline metabolism in cancer+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-LS
Collinsella	IL-13	Collinsella-Gastric cancer+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-LS
Collinsella	IL-13	Collinsella-ErbB signaling pathway+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-LS
Collinsella	IL-13	Collinsella-Phosphatidylinositol signaling system+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	DM-LS
total_blood_scfa+blood	IL-13	total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.168	0.00264	no	no	no	up	up	no	DM-LS
[Eubacterium]	IL-13	[Eubacterium]-Viral myocarditis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0692	0.00264	no	no	no	up	up	no	DM-LS
[Eubacterium]	IL-13	[Eubacterium]-Pathogenic Escherichia coli infection-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0692	0.00264	no	no	no	up	up	no	DM-LS
[Eubacterium]	IL-13	[Eubacterium]-Phagosome-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.0692	0.00264	no	no	no	up	up	no	DM-LS
LCA+stool	IL-13	LCA+stool-ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.314	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia+Apoptosis-Cushing syndrome+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia+LCA+stool-ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia-4-hydroxybenzoic acid+stool+ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia+Apoptosis+Viral myocarditis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia+Apoptosis-Glucagon signaling pathway+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia+Apoptosis+Fc gamma R-mediated phagocytosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia+Apoptosis-Inflammatory mediator regulation of TRP channels+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia-18:0/18:2-PI+blood-Creatinine+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia+Apoptosis+IL-17 signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia-18:0/18:2-PI+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia+Apoptosis+Neutrophil extracellular trap formation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia+Apoptosis-Melanogenesis+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia-Retrograde endocannabinoid signaling-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia+Apoptosis-Long-term potentiation+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia+Apoptosis+Lipid and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia+Apoptosis+Pathogenic Escherichia coli infection-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia+Apoptosis+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia-Retrograde endocannabinoid signaling+CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia+Apoptosis+Staphylococcus aureus infection-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia+Apoptosis-Aldosterone synthesis and secretion+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Akkermansia	IL-13	Akkermansia+Apoptosis-Adrenergic signaling in cardiomyocytes+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	DM-LS
Bifidobacterium	IL-13	Bifidobacterium+Chemical carcinogenesis - receptor activation+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.105	0.00264	no	dn	no	up	up	no	DM-LS
Ruminococcus	IL-13	Ruminococcus+Type I diabetes mellitus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	DM-LS
Ruminococcus	IL-13	Ruminococcus+Endocytosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	DM-LS
Ruminococcus	IL-13	Ruminococcus+Allograft rejection-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	DM-LS
Ruminococcus	IL-13	Ruminococcus+22:6n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	DM-LS
Ruminococcus	IL-13	Ruminococcus+Graft-versus-host disease-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	DM-LS
Ruminococcus	IL-13	Ruminococcus+Phagosome-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	DM-LS
Ruminococcus	IL-13	Ruminococcus+Cell adhesion molecules-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	DM-LS
Ruminococcus	IL-13	Ruminococcus+Autoimmune thyroid disease-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	DM-LS
GCDCA+blood	IL-13	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.31	0.00264	no	no	no	up	up	no	DM-LS
Succinivibrio	IL-13	Succinivibrio-L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.138	0.00264	no	no	no	up	up	no	DM-LS
Succinivibrio	IL-13	Succinivibrio-Phospholipase D signaling pathway+Cushing syndrome+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.138	0.00264	no	no	no	up	up	no	DM-LS
Succinivibrio	IL-13	Succinivibrio-Phospholipase D signaling pathway-MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.138	0.00264	no	no	no	up	up	no	DM-LS
Succinivibrio	IL-13	Succinivibrio-L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.138	0.00264	no	no	no	up	up	no	DM-LS
Succinivibrio	IL-13	Succinivibrio-Phospholipase D signaling pathway+Chemical carcinogenesis - receptor activation+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.138	0.00264	no	no	no	up	up	no	DM-LS
Succinivibrio	IL-13	Succinivibrio-L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.138	0.00264	no	no	no	up	up	no	DM-LS
Succinivibrio	IL-13	Succinivibrio-L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.138	0.00264	no	no	no	up	up	no	DM-LS
Succinivibrio	IL-13	Succinivibrio-Phospholipase D signaling pathway-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.138	0.00264	no	no	no	up	up	no	DM-LS
ACA+blood	IL-13	ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.338	0.00264	no	no	no	up	up	no	DM-LS
DCA+stool	IL-13	DCA+stool-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.195	0.00264	no	no	no	up	up	no	DM-LS
DCA+stool	IL-13	DCA+stool-ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.195	0.00264	no	no	no	up	up	no	DM-LS
Butyric acid+stool	IL-13	Butyric acid+stool+Propionic acid+stool-MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.102	0.00264	dn	no	no	up	up	no	DM-LS
Butyric acid+stool	IL-13	Butyric acid+stool+8-HETE+blood-ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.102	0.00264	dn	no	no	up	up	no	DM-LS
Butyric acid+stool	IL-13	Butyric acid+stool+Propionic acid+stool-ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.102	0.00264	dn	no	no	up	up	no	DM-LS
Butyric acid+stool	IL-13	Butyric acid+stool-16:1/16:1-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.102	0.00264	dn	no	no	up	up	no	DM-LS
Butyric acid+stool	IL-13	Butyric acid+stool+AA+blood+Choline+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.102	0.00264	dn	no	no	up	up	no	DM-LS
Butyric acid+stool	IL-13	Butyric acid+stool+Propionic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.102	0.00264	dn	no	no	up	up	no	DM-LS
Butyric acid+stool	IL-13	Butyric acid+stool-Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.102	0.00264	dn	no	no	up	up	no	DM-LS
4-hydroxybenzoic acid+stool	IL-13	4-hydroxybenzoic acid+stool+ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.00264	no	dn	no	up	up	no	DM-LS
GCA+blood	IL-13	GCA+blood+TCA+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.16	0.00264	no	no	no	up	up	no	DM-LS
ACA+stool	IL-13	ACA+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.417	0.00264	no	no	no	up	up	no	DM-LS
ACA+stool	IL-13	ACA+stool+20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.417	0.00264	no	no	no	up	up	no	DM-LS
CDCA+blood	IL-13	CDCA+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.506	0.00264	no	no	no	up	up	no	DM-LS
CDCA+blood	IL-13	CDCA+blood-Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.506	0.00264	no	no	no	up	up	no	DM-LS
capric acid C6+blood	IL-13	capric acid C6+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.433	0.00264	no	no	no	up	up	no	DM-LS
capric acid C6+blood	IL-13	capric acid C6+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.433	0.00264	no	no	no	up	up	no	DM-LS
capric acid C6+blood	IL-13	capric acid C6+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.433	0.00264	no	no	no	up	up	no	DM-LS
Pyramidobacter	IL-13	Pyramidobacter-Carbon metabolism-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.45	0.00264	no	no	no	up	up	no	DM-LS
Pyramidobacter	IL-13	Pyramidobacter+Glucagon signaling pathway+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.45	0.00264	no	no	no	up	up	no	DM-LS
Prevotella	IL-13	Prevotella+Aldosterone synthesis and secretion+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	DM-LS
Prevotella	IL-13	Prevotella+Adrenergic signaling in cardiomyocytes+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	DM-LS
Prevotella	IL-13	Prevotella+Chemical carcinogenesis - receptor activation+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	DM-LS
Prevotella	IL-13	Prevotella+Inflammatory mediator regulation of TRP channels+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	DM-LS
Prevotella	IL-13	Prevotella-Carbon metabolism-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	DM-LS
Prevotella	IL-13	Prevotella+Amphetamine addiction+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	DM-LS
Prevotella	IL-13	Prevotella+Dopaminergic synapse+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	DM-LS
Prevotella	IL-13	Prevotella+Cushing syndrome+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	DM-LS
Prevotella	IL-13	Prevotella+Melanogenesis+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	DM-LS
TCA+blood	IL-13	TCA+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.339	0.00264	no	no	no	up	up	no	DM-LS
iso-DCA+blood	IL-13	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.38	0.00264	no	no	no	up	up	no	DM-LS
iso-DCA+blood	IL-13	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.38	0.00264	no	no	no	up	up	no	DM-LS
iso-DCA+blood	IL-13	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.38	0.00264	no	no	no	up	up	no	DM-LS
HCA+stool	IL-13	HCA+stool-Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.155	0.00264	no	no	no	up	up	no	DM-LS
Roseburia	IL-13	Roseburia-20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.495	0.00264	no	no	no	up	up	no	DM-LS
12-ketoDCA+stool	IL-13	12-ketoDCA+stool+DCA+stool-ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.505	0.00264	no	no	no	up	up	no	DM-LS
12-ketoDCA+stool	IL-13	12-ketoDCA+stool+LCA+stool-ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.505	0.00264	no	no	no	up	up	no	DM-LS
12-ketoDCA+stool	IL-13	12-ketoDCA+stool+18:0/18:1-PE+blood-ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.505	0.00264	no	no	no	up	up	no	DM-LS
12-ketoDCA+stool	IL-13	12-ketoDCA+stool+DCA+stool-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.505	0.00264	no	no	no	up	up	no	DM-LS
12-ketoDCA+stool	IL-13	12-ketoDCA+stool-Glycine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.505	0.00264	no	no	no	up	up	no	DM-LS
12-ketoDCA+stool	IL-13	12-ketoDCA+stool+18:0/18:1-PE+blood-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.505	0.00264	no	no	no	up	up	no	DM-LS
12-ketoDCA+stool	IL-13	12-ketoDCA+stool-Glycine+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.505	0.00264	no	no	no	up	up	no	DM-LS
GLCA+blood	IL-13	GLCA+blood-PUFA/MUFA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.319	0.00264	no	no	no	up	up	no	DM-LS
GLCA+blood	IL-13	GLCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.319	0.00264	no	no	no	up	up	no	DM-LS
L-Tryptophan+stool	IL-13	L-Tryptophan+stool+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00264	no	no	no	up	up	no	DM-LS
CA+blood	IL-13	CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.606	0.00264	no	no	no	up	up	no	DM-LS
L-Phenylalanine+stool	IL-13	L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00264	no	no	no	up	up	no	DM-LS
L-Phenylalanine+stool	IL-13	L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00264	no	no	no	up	up	no	DM-LS
L-Phenylalanine+stool	IL-13	L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00264	no	no	no	up	up	no	DM-LS
butyric acid C4+blood	IL-13	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.407	0.00264	no	no	no	up	up	no	DM-LS
GCA+stool	IL-13	GCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-LS
GCA+stool	IL-13	GCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-LS
GCA+stool	IL-13	GCA+stool+nutriCA+stool+CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-LS
GCA+stool	IL-13	GCA+stool+GCDCA+stool+CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-LS
GCA+stool	IL-13	GCA+stool+nutriCA+stool-n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-LS
GCA+stool	IL-13	GCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-LS
GCA+stool	IL-13	GCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-LS
GCA+stool	IL-13	GCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-LS
GCA+stool	IL-13	GCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-LS
GCA+stool	IL-13	GCA+stool+GCDCA+stool-Creatinine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-LS
GCA+stool	IL-13	GCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-LS
GCA+stool	IL-13	GCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	DM-LS
T-a-MCA+blood	IL-13	T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.478	0.00264	no	no	no	up	up	no	DM-LS
Coprococcus	IL-13	Coprococcus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	DM-LS
Oscillospira	IL-13	Oscillospira-Adrenergic signaling in cardiomyocytes+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.62	0.00264	no	no	no	up	up	no	DM-LS
Oscillospira	IL-13	Oscillospira+Peroxisome-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.62	0.00264	no	no	no	up	up	no	DM-LS
HCA+blood	IL-13	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.544	0.00264	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-13	iso-LCA+stool-CDCA+blood-Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-13	iso-LCA+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-13	iso-LCA+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-13	iso-LCA+stool-18:3n6+blood-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-13	iso-LCA+stool-nutriCA+stool+CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-13	iso-LCA+stool-18:3n6+blood-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-13	iso-LCA+stool-Glycine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-13	iso-LCA+stool-nutriCA+stool-n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-13	iso-LCA+stool-18:1-LPE+blood-n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-13	iso-LCA+stool-Sarcosine+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-13	iso-LCA+stool-18:1-LPE+blood-22:6n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-13	iso-LCA+stool-CDCA+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-13	iso-LCA+stool-Glycine+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-13	iso-LCA+stool+LCA+stool-ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	DM-LS
2-methyl-butyric acid m-C4+blood	IL-13	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.262	0.00264	no	no	no	up	up	no	DM-LS
DCA+blood	IL-13	DCA+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.122	0.00264	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-13	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00264	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-13	3-(3-Hydroxyphenyl)propanoic acid+stool-T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00264	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-13	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00264	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-13	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00264	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-13	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2/16:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00264	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-13	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00264	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-13	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00264	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-13	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00264	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-13	3-(3-Hydroxyphenyl)propanoic acid+stool+UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00264	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-13	3-(3-Hydroxyphenyl)propanoic acid+stool-16:0/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00264	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-13	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00264	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-13	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00264	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-13	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2n6c+blood+20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00264	no	no	no	up	up	no	DM-LS
Indole-3-Acetic acid+stool	IL-13	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00264	no	no	no	up	up	no	DM-LS
Indole-3-Acetic acid+stool	IL-13	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00264	no	no	no	up	up	no	DM-LS
Indole-3-Acetic acid+stool	IL-13	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00264	no	no	no	up	up	no	DM-LS
Indole-3-Acetic acid+stool	IL-13	Indole-3-Acetic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00264	no	no	no	up	up	no	DM-LS
Indole-3-Acetic acid+stool	IL-13	Indole-3-Acetic acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00264	no	no	no	up	up	no	DM-LS
Indole-3-Acetic acid+stool	IL-13	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00264	no	no	no	up	up	no	DM-LS
TCA+stool	IL-13	TCA+stool-16:0/20:5-PC+blood+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-LS
TCA+stool	IL-13	TCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-LS
TCA+stool	IL-13	TCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-LS
TCA+stool	IL-13	TCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-LS
TCA+stool	IL-13	TCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-LS
TCA+stool	IL-13	TCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-LS
TCA+stool	IL-13	TCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-LS
TCA+stool	IL-13	TCA+stool-16:0/20:5-PC+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-LS
TCA+stool	IL-13	TCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-LS
TCA+stool	IL-13	TCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-LS
TCA+stool	IL-13	TCA+stool+18:1/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-LS
TCA+stool	IL-13	TCA+stool+16:0/20:3-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-LS
TCA+stool	IL-13	TCA+stool-16:0/20:5-PC+blood-20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-LS
TCA+stool	IL-13	TCA+stool+18:1/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-LS
TCA+stool	IL-13	TCA+stool+16:0/20:3-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-LS
TCA+stool	IL-13	TCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-LS
TCA+stool	IL-13	TCA+stool-16:0/20:5-PC+blood+CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-13	HDCA+stool-18:1/20:3-PC+blood-CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-13	HDCA+stool-nutriCA+stool+CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-13	HDCA+stool+LCA+stool-ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-13	HDCA+stool-18:1-LPE+blood-22:6n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-13	HDCA+stool-18:1/20:3-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-13	HDCA+stool-18:1-LPC+blood+20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-13	HDCA+stool-16:0/20:3-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-13	HDCA+stool-18:1/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-13	HDCA+stool+EPA+blood+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-13	HDCA+stool-nutriCA+stool-n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-13	HDCA+stool-18:1-LPE+blood-n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-13	HDCA+stool-16:0/20:3-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-13	HDCA+stool-18:1/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	DM-LS
Lachnospira	IL-13	Lachnospira+Choline+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.279	0.00264	no	no	no	up	up	no	DM-LS
Fusobacterium	IL-13	Fusobacterium+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.628	0.00264	no	no	no	up	up	no	DM-LS
Fusobacterium	IL-13	Fusobacterium+MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.628	0.00264	no	no	no	up	up	no	DM-LS
isobutyric acid C4+blood	IL-13	isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.0151	0.00264	up	up	no	up	up	no	DM-LS
GCDCA+stool	IL-13	GCDCA+stool-Creatinine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	DM-LS
GCDCA+stool	IL-13	GCDCA+stool+CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-Propionic acid+stool-ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-Propionic acid+stool-MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-Propionic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	DM-LS
Odoribacter	IL-13	Odoribacter+Choline+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-13	Isobutyric acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.408	0.00264	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-13	Isobutyric acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.408	0.00264	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-13	Isobutyric acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.408	0.00264	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-13	Isobutyric acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.408	0.00264	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-13	Isobutyric acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.408	0.00264	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-13	Isobutyric acid+stool-nutriCA+stool+CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.408	0.00264	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-13	Isobutyric acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.408	0.00264	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-13	Isobutyric acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.408	0.00264	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-13	Isobutyric acid+stool-nutriCA+stool-n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.408	0.00264	no	no	no	up	up	no	DM-LS
Lachnobacterium	IL-13	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.867	0.00264	no	no	no	up	up	no	DM-LS
Kynurenic acid+stool	IL-13	Kynurenic acid+stool-nutriCA+stool+CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00264	dn	dn	no	up	up	no	DM-LS
Kynurenic acid+stool	IL-13	Kynurenic acid+stool-nutriCA+stool-n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00264	dn	dn	no	up	up	no	DM-LS
Kynurenic acid+stool	IL-13	Kynurenic acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00264	dn	dn	no	up	up	no	DM-LS
Kynurenic acid+stool	IL-13	Kynurenic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00264	dn	dn	no	up	up	no	DM-LS
Anaerostipes	IL-13	Anaerostipes-Non-small cell lung cancer+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.568	0.00264	no	no	no	up	up	no	DM-LS
Anaerostipes	IL-13	Anaerostipes+TUDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.568	0.00264	no	no	no	up	up	no	DM-LS
TUDCA+stool	IL-13	TUDCA+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.241	0.00264	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-13	Isovaleric acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.343	0.00264	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-13	Isovaleric acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.343	0.00264	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-13	Isovaleric acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.343	0.00264	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-13	Isovaleric acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.343	0.00264	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-13	Isovaleric acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.343	0.00264	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-13	Isovaleric acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.343	0.00264	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-13	Isovaleric acid+stool-nutriCA+stool-n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.343	0.00264	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-13	Isovaleric acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.343	0.00264	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-13	Isovaleric acid+stool-nutriCA+stool+CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_scfa	serum_cytokines	0.343	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Arachidonic acid metabolism+Biosynthesis of amino acids-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Betaine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Glutathione metabolism-Choline metabolism in cancer+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Arachidonic acid metabolism-Choline metabolism in cancer+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Glutathione metabolism-Cholinergic synapse+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Glutathione metabolism-mRNA surveillance pathway+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Arachidonic acid metabolism-mRNA surveillance pathway+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Glutathione metabolism-Non-small cell lung cancer+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Arachidonic acid metabolism-Non-small cell lung cancer+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+18:0/20:2-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Glutathione metabolism-Colorectal cancer+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Arachidonic acid metabolism-Colorectal cancer+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Arachidonic acid metabolism-Cell cycle+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Arachidonic acid metabolism+Choline+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Glutathione metabolism-ErbB signaling pathway+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Arachidonic acid metabolism-ErbB signaling pathway+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Glutathione metabolism-Phosphatidylinositol signaling system+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Arachidonic acid metabolism-Phosphatidylinositol signaling system+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella-18:0/22:6-PA+blood+22:6n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Glutathione metabolism-Gastric cancer+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Arachidonic acid metabolism-Gastric cancer+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Glutathione metabolism-Glioma+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Arachidonic acid metabolism-Glioma+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Glutathione metabolism-Signaling pathways regulating pluripotency of stem cells+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Arachidonic acid metabolism-Signaling pathways regulating pluripotency of stem cells+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Glutathione metabolism-Spliceosome+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Arachidonic acid metabolism-Spliceosome+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Betaine+blood-CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Glutathione metabolism-Long-term potentiation+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-13	Paraprevotella+Arachidonic acid metabolism-Long-term potentiation+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	DM-LS
iso-LCA+blood	IL-13	iso-LCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.507	0.00264	no	no	no	up	up	no	DM-LS
Phenylacetic acid+stool	IL-13	Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.785	0.00264	no	no	no	up	up	no	DM-LS
Gemmiger	IL-13	Gemmiger-18:1-LPC+blood+20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-LS
Gemmiger	IL-13	Gemmiger+L-Phenylalanine+blood+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-13	GDCA+stool-L-Phenylalanine+blood+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-13	GDCA+stool-L-Isoleucine+blood+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-13	GDCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-13	GDCA+stool-L-Histidine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-13	GDCA+stool+20:3/18:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-13	GDCA+stool-L-Isoleucine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-13	GDCA+stool+Glycine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-13	GDCA+stool+24:1+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-13	GDCA+stool-Propionic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-13	GDCA+stool-L-Histidine+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-13	GDCA+stool+Glycine+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-13	GDCA+stool-Propionic acid+stool-MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-13	GDCA+stool+20:3/18:0-PC+blood+ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-13	GDCA+stool+24:1+blood+ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-13	GDCA+stool-Propionic acid+stool-ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-13	GDCA+stool+20:3/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	DM-LS
Methanobrevibacter	IL-13	Methanobrevibacter+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.629	0.00264	no	no	no	up	up	no	DM-LS
L-Tyrosine+stool	IL-13	L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00264	no	no	no	up	up	no	DM-LS
CDCA+stool	IL-13	CDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.663	0.00264	no	no	no	up	up	no	DM-LS
CA+stool	IL-13	CA+stool+CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.827	0.00264	no	no	no	up	up	no	DM-LS
Slackia	IL-13	Slackia+Platinum drug resistance+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.94	0.00264	no	no	no	up	up	no	DM-LS
Slackia	IL-13	Slackia-Neutrophil extracellular trap formation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.94	0.00264	no	no	no	up	up	no	DM-LS
Slackia	IL-13	Slackia-Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.94	0.00264	no	no	no	up	up	no	DM-LS
HDCA+blood	IL-13	HDCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.483	0.00264	no	no	no	up	up	no	DM-LS
UDCA+stool	IL-13	UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.266	0.00264	no	no	no	up	up	no	DM-LS
TDCA+stool	IL-13	TDCA+stool+UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.963	0.00264	no	no	no	up	up	no	DM-LS
nutriCA+stool	IL-13	nutriCA+stool+CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.481	0.00264	no	no	no	up	up	no	DM-LS
nutriCA+stool	IL-13	nutriCA+stool-n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.481	0.00264	no	no	no	up	up	no	DM-LS
GDCA+blood	IL-13	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.632	0.00264	no	no	no	up	up	no	DM-LS
acetic acid C2+blood	IL-13	acetic acid C2+blood+total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.000193	0.00264	up	dn	no	up	up	no	DM-LS
acetic acid C2+blood	IL-13	acetic acid C2+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.000193	0.00264	up	dn	no	up	up	no	DM-LS
acetic acid C2+blood	IL-13	acetic acid C2+blood+capric acid C6+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.000193	0.00264	up	dn	no	up	up	no	DM-LS
acetic acid C2+blood	IL-13	acetic acid C2+blood+capric acid C6+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.000193	0.00264	up	dn	no	up	up	no	DM-LS
acetic acid C2+blood	IL-13	acetic acid C2+blood-d18:1-14:1-SM+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.000193	0.00264	up	dn	no	up	up	no	DM-LS
acetic acid C2+blood	IL-13	acetic acid C2+blood+capric acid C6+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.000193	0.00264	up	dn	no	up	up	no	DM-LS
acetic acid C2+blood	IL-13	acetic acid C2+blood-d18:1-14:1-SM+blood-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.000193	0.00264	up	dn	no	up	up	no	DM-LS
isovaleric acid iso-C5+blood	IL-13	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-13	Indirect	serum_scfa	serum_cytokines	0.117	0.00264	no	no	no	up	up	no	DM-LS
Adlercreutzia	IL-13	Adlercreutzia-16:0/20:5-PC+blood-20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.548	0.00264	no	no	no	up	up	no	DM-LS
Adlercreutzia	IL-13	Adlercreutzia+18:1-LPC+blood+20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.548	0.00264	no	no	no	up	up	no	DM-LS
Adlercreutzia	IL-13	Adlercreutzia-EPA+blood+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.548	0.00264	no	no	no	up	up	no	DM-LS
Adlercreutzia	IL-13	Adlercreutzia-16:0/20:5-PC+blood+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.548	0.00264	no	no	no	up	up	no	DM-LS
Adlercreutzia	IL-13	Adlercreutzia-16:0/20:5-PC+blood+CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.548	0.00264	no	no	no	up	up	no	DM-LS
Adlercreutzia	IL-13	Adlercreutzia-16:0/20:5-PC+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.548	0.00264	no	no	no	up	up	no	DM-LS
Adlercreutzia	IL-13	Adlercreutzia+16:0/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.548	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium+cGMP-PKG signaling pathway+Lipid and atherosclerosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium+cGMP-PKG signaling pathway+Endocytosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium+cGMP-PKG signaling pathway+IL-17 signaling pathway-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium+PUFA/MUFA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium-14:0/20:4-PC+blood-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium-Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
 Clostridium	IL-13	Clostridium+Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	NA	0.00264	NA	NA	NA	up	up	no	DM-LS
Clostridium	IL-13	Clostridium-Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
 Clostridium	IL-13	Clostridium+Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	NA	0.00264	NA	NA	NA	up	up	no	DM-LS
Clostridium	IL-13	Clostridium+cGMP-PKG signaling pathway+Fc gamma R-mediated phagocytosis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium+cGMP-PKG signaling pathway+Neutrophil extracellular trap formation-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium+cGMP-PKG signaling pathway+Pathogenic Escherichia coli infection-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium-18:0/20:2-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium+CDCA+blood-Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium-14:0/20:4-PC+blood-Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium-Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
 Clostridium	IL-13	Clostridium+Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	NA	0.00264	NA	NA	NA	up	up	no	DM-LS
Clostridium	IL-13	Clostridium-Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
 Clostridium	IL-13	Clostridium+Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	NA	0.00264	NA	NA	NA	up	up	no	DM-LS
Clostridium	IL-13	Clostridium-14:0/20:4-PC+blood-Creatinine+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium-14:0/18:2-PC+blood-Creatinine+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium-14:0/20:4-PC+blood-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium+CDCA+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium-14:0/20:4-PC+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium+cGMP-PKG signaling pathway+MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
Clostridium	IL-13	Clostridium-14:0/18:2-PC+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood-20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-TCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-13	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+CA+blood+Eotaxin-GM-CSF+IL-13	Indirect	stool_bileacids	serum_cytokines	0.48	0.00264	no	no	no	up	up	no	DM-LS
12-ketoDCA+blood	IL-13	12-ketoDCA+blood-8-HETE+blood-ACA+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.517	0.00264	no	no	no	up	up	no	DM-LS
12-ketoDCA+blood	IL-13	12-ketoDCA+blood-20:3-LPE+blood-22:6n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.517	0.00264	no	no	no	up	up	no	DM-LS
12-ketoDCA+blood	IL-13	12-ketoDCA+blood-20:3-LPE+blood+Choline+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.517	0.00264	no	no	no	up	up	no	DM-LS
12-ketoDCA+blood	IL-13	12-ketoDCA+blood-L-Lysine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.517	0.00264	no	no	no	up	up	no	DM-LS
12-ketoDCA+blood	IL-13	12-ketoDCA+blood-L-Arginine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.517	0.00264	no	no	no	up	up	no	DM-LS
12-ketoDCA+blood	IL-13	12-ketoDCA+blood-20:3-LPE+blood-n3+blood-Eotaxin-GM-CSF+IL-13	Indirect	serum_bileacids	serum_cytokines	0.517	0.00264	no	no	no	up	up	no	DM-LS
Butyricicoccus	IL-13	Butyricicoccus+Allograft rejection-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.852	0.00264	no	no	no	up	up	no	DM-LS
Butyricicoccus	IL-13	Butyricicoccus+Viral myocarditis-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.852	0.00264	no	no	no	up	up	no	DM-LS
Butyricicoccus	IL-13	Butyricicoccus+Cell adhesion molecules-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.852	0.00264	no	no	no	up	up	no	DM-LS
Butyricicoccus	IL-13	Butyricicoccus+Type I diabetes mellitus-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.852	0.00264	no	no	no	up	up	no	DM-LS
Butyricicoccus	IL-13	Butyricicoccus+Graft-versus-host disease-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.852	0.00264	no	no	no	up	up	no	DM-LS
Butyricicoccus	IL-13	Butyricicoccus+Phagosome-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.852	0.00264	no	no	no	up	up	no	DM-LS
Butyricicoccus	IL-13	Butyricicoccus+Autoimmune thyroid disease-Eotaxin-GM-CSF+IL-13	Indirect	Genus	serum_cytokines	0.852	0.00264	no	no	no	up	up	no	DM-LS
Blautia	IL-4	Blautia-20:5/18:0-PC+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	DM-LS
Parabacteroides	IL-4	Parabacteroides-Glucagon signaling pathway+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	4.19E-05	0.858	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-4	Parabacteroides-Spliceosome+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	4.19E-05	0.858	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-4	Parabacteroides+Choline+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	4.19E-05	0.858	no	up	up	no	no	no	DM-LS
Dorea	IL-4	Dorea-18:0/22:6-PE+blood+IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.00362	0.858	up	no	dn	no	no	no	DM-LS
Dorea	IL-4	Dorea-Lipid and atherosclerosis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.00362	0.858	up	no	dn	no	no	no	DM-LS
Faecalibacterium	IL-4	Faecalibacterium-Cysteine+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	IL-4	Faecalibacterium-Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	DM-LS
TUDCA+blood	IL-4	TUDCA+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.0282	0.858	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	IL-4	isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.0458	0.858	no	no	dn	no	no	no	DM-LS
Bacteroides	IL-4	Bacteroides+n3+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-LS
Bacteroides	IL-4	Bacteroides+22:6n3+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	DM-LS
Propionic acid+stool	IL-4	Propionic acid+stool-UFA%+blood-Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.0436	0.858	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IL-4	Propionic acid+stool-MUFA%+blood-Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.0436	0.858	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IL-4	Propionic acid+stool-ACA+blood-Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.0436	0.858	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IL-4	Propionic acid+stool+18:0/22:6-PE+blood+IL-1ra-IL-4	Indirect	stool_scfa	serum_cytokines	0.0436	0.858	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IL-4	Propionic acid+stool+16:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_scfa	serum_cytokines	0.0436	0.858	dn	no	up	no	no	no	DM-LS
[Ruminococcus]	IL-4	[Ruminococcus]-FGF basic+IL-17A+IL-4	Indirect	Genus	serum_cytokines	0.0679	0.858	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	IL-4	[Ruminococcus]-UFA%+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0679	0.858	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	IL-4	[Ruminococcus]-20:5/18:0-PC+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0679	0.858	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	IL-4	[Ruminococcus]-MUFA%+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0679	0.858	no	no	dn	no	no	no	DM-LS
GUDCA+blood	IL-4	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.0766	0.858	no	no	dn	no	no	no	DM-LS
Acetic acid+stool	IL-4	Acetic acid+stool-UFA%+blood-Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.0656	0.858	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	IL-4	Acetic acid+stool-Cysteine+blood-Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.0656	0.858	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	IL-4	Acetic acid+stool-Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_scfa	serum_cytokines	0.0656	0.858	dn	no	no	no	no	no	DM-LS
Alistipes	IL-4	Alistipes-L-Arginine+blood+UFA%+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0114	0.858	no	up	no	no	no	no	DM-LS
Alistipes	IL-4	Alistipes-HIF-1 signaling pathway+Measles-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0114	0.858	no	up	no	no	no	no	DM-LS
Alistipes	IL-4	Alistipes-L-Aspartic acid+blood+n3+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0114	0.858	no	up	no	no	no	no	DM-LS
Alistipes	IL-4	Alistipes+12-ketoDCA+stool+18:0/22:6-PE+blood+IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.0114	0.858	no	up	no	no	no	no	DM-LS
Butyricimonas	IL-4	Butyricimonas+20:5/18:0-PC+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.17	0.858	no	no	no	no	no	no	DM-LS
Collinsella	IL-4	Collinsella-Signaling pathways regulating pluripotency of stem cells+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-LS
Collinsella	IL-4	Collinsella-Colorectal cancer+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-LS
Collinsella	IL-4	Collinsella-Glioma+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-LS
Collinsella	IL-4	Collinsella-Long-term potentiation+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-LS
Collinsella	IL-4	Collinsella-Choline metabolism in cancer+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-LS
Collinsella	IL-4	Collinsella-Gastric cancer+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-LS
Collinsella	IL-4	Collinsella-ErbB signaling pathway+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-LS
Collinsella	IL-4	Collinsella-Phosphatidylinositol signaling system+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	IL-4	total_blood_scfa+blood+TUDCA+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.168	0.858	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-4	[Eubacterium]-Viral myocarditis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0692	0.858	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-4	[Eubacterium]-Pathogenic Escherichia coli infection-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0692	0.858	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-4	[Eubacterium]-Phagosome-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0692	0.858	no	no	no	no	no	no	DM-LS
LCA+stool	IL-4	LCA+stool-ACA+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	DM-LS
Akkermansia	IL-4	Akkermansia+18:0/22:6-PE+blood+IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.23	0.858	no	no	no	no	no	no	DM-LS
Bifidobacterium	IL-4	Bifidobacterium-FGF basic+IL-17A+IL-4	Indirect	Genus	serum_cytokines	0.105	0.858	no	dn	no	no	no	no	DM-LS
Bifidobacterium	IL-4	Bifidobacterium+Chemical carcinogenesis - receptor activation+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.105	0.858	no	dn	no	no	no	no	DM-LS
Ruminococcus	IL-4	Ruminococcus+Type I diabetes mellitus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-4	Ruminococcus+Endocytosis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-4	Ruminococcus+Allograft rejection-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-4	Ruminococcus+22:6n3+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-4	Ruminococcus+Graft-versus-host disease-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-4	Ruminococcus+Phagosome-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-4	Ruminococcus+Cell adhesion molecules-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-4	Ruminococcus+Autoimmune thyroid disease-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	DM-LS
GCDCA+blood	IL-4	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.31	0.858	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-4	Succinivibrio-L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.138	0.858	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-4	Succinivibrio-L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.138	0.858	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-4	Succinivibrio-L-Phenylalanine+stool+n3+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.138	0.858	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-4	Succinivibrio-Phospholipase D signaling pathway+Cushing syndrome+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.138	0.858	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-4	Succinivibrio-Phospholipase D signaling pathway-MUFA%+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.138	0.858	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-4	Succinivibrio-L-Phenylalanine+stool+Cysteine+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.138	0.858	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-4	Succinivibrio-Phospholipase D signaling pathway+Chemical carcinogenesis - receptor activation+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.138	0.858	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-4	Succinivibrio-L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.138	0.858	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-4	Succinivibrio-L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.138	0.858	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-4	Succinivibrio-Phospholipase D signaling pathway-UFA%+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.138	0.858	no	no	no	no	no	no	DM-LS
ACA+blood	IL-4	ACA+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.338	0.858	no	no	no	no	no	no	DM-LS
DCA+stool	IL-4	DCA+stool-UFA%+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.195	0.858	no	no	no	no	no	no	DM-LS
DCA+stool	IL-4	DCA+stool-ACA+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.195	0.858	no	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-4	Butyric acid+stool-Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_scfa	serum_cytokines	0.102	0.858	dn	no	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	IL-4	4-hydroxybenzoic acid+stool+ACA+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.858	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	IL-4	4-hydroxybenzoic acid+stool-Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.858	no	dn	no	no	no	no	DM-LS
GCA+blood	IL-4	GCA+blood+FGF basic+IL-17A+IL-4	Indirect	serum_bileacids	serum_cytokines	0.16	0.858	no	no	no	no	no	no	DM-LS
ACA+stool	IL-4	ACA+stool+GPC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.417	0.858	no	no	no	no	no	no	DM-LS
ACA+stool	IL-4	ACA+stool+20:5/18:0-PC+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.417	0.858	no	no	no	no	no	no	DM-LS
ACA+stool	IL-4	ACA+stool+20:2+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.417	0.858	no	no	no	no	no	no	DM-LS
CDCA+blood	IL-4	CDCA+blood-MUFA%+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.506	0.858	no	no	no	no	no	no	DM-LS
CDCA+blood	IL-4	CDCA+blood-Cysteine+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.506	0.858	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-4	capric acid C6+blood+UFA%+blood-Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.433	0.858	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-4	capric acid C6+blood+TUDCA+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.433	0.858	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-4	capric acid C6+blood+MUFA%+blood-Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.433	0.858	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-4	Pyramidobacter-Carbon metabolism-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.45	0.858	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-4	Pyramidobacter+Glucagon signaling pathway+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.45	0.858	no	no	no	no	no	no	DM-LS
Prevotella	IL-4	Prevotella-Proteasome-IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	DM-LS
Prevotella	IL-4	Prevotella+Aldosterone synthesis and secretion+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	DM-LS
Prevotella	IL-4	Prevotella+Adrenergic signaling in cardiomyocytes+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	DM-LS
Prevotella	IL-4	Prevotella+Chemical carcinogenesis - receptor activation+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	DM-LS
Prevotella	IL-4	Prevotella+Inflammatory mediator regulation of TRP channels+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	DM-LS
Prevotella	IL-4	Prevotella-Carbon metabolism-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	DM-LS
Prevotella	IL-4	Prevotella+Amphetamine addiction+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	DM-LS
Prevotella	IL-4	Prevotella+Dopaminergic synapse+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	DM-LS
Prevotella	IL-4	Prevotella+Cushing syndrome+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	DM-LS
Prevotella	IL-4	Prevotella+Melanogenesis+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	DM-LS
TCA+blood	IL-4	TCA+blood+FGF basic+IL-17A+IL-4	Indirect	serum_bileacids	serum_cytokines	0.339	0.858	no	no	no	no	no	no	DM-LS
TCA+blood	IL-4	TCA+blood+TUDCA+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.339	0.858	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-4	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.38	0.858	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-4	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.38	0.858	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-4	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.38	0.858	no	no	no	no	no	no	DM-LS
HCA+stool	IL-4	HCA+stool-18:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.155	0.858	no	no	no	no	no	no	DM-LS
HCA+stool	IL-4	HCA+stool-GPC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.155	0.858	no	no	no	no	no	no	DM-LS
HCA+stool	IL-4	HCA+stool-Cysteine+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.155	0.858	no	no	no	no	no	no	DM-LS
Roseburia	IL-4	Roseburia-20:2+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.495	0.858	no	no	no	no	no	no	DM-LS
Roseburia	IL-4	Roseburia-20:1+blood-IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.495	0.858	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	IL-4	12-ketoDCA+stool+18:0/22:6-PE+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.505	0.858	no	no	no	no	no	no	DM-LS
GLCA+blood	IL-4	GLCA+blood-Sarcosine+blood-FGF basic+IL-17A+IL-4	Indirect	serum_bileacids	serum_cytokines	0.319	0.858	no	no	no	no	no	no	DM-LS
GLCA+blood	IL-4	GLCA+blood-PUFA/MUFA+blood+UFA%+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.319	0.858	no	no	no	no	no	no	DM-LS
GLCA+blood	IL-4	GLCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.319	0.858	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	IL-4	L-Tryptophan+stool+Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.557	0.858	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	IL-4	L-Tryptophan+stool+n3+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.557	0.858	no	no	no	no	no	no	DM-LS
CA+blood	IL-4	CA+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.606	0.858	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IL-4	L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.398	0.858	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IL-4	L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.398	0.858	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IL-4	L-Phenylalanine+stool+n3+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.398	0.858	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IL-4	L-Phenylalanine+stool+Cysteine+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.398	0.858	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	IL-4	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.407	0.858	no	no	no	no	no	no	DM-LS
GCA+stool	IL-4	GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	IL-4	T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.478	0.858	no	no	no	no	no	no	DM-LS
Coprococcus	IL-4	Coprococcus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	DM-LS
Oscillospira	IL-4	Oscillospira-Adrenergic signaling in cardiomyocytes+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.62	0.858	no	no	no	no	no	no	DM-LS
Oscillospira	IL-4	Oscillospira+Peroxisome-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.62	0.858	no	no	no	no	no	no	DM-LS
HCA+blood	IL-4	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.544	0.858	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-4	iso-LCA+stool+Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.72	0.858	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	IL-4	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.262	0.858	no	no	no	no	no	no	DM-LS
DCA+blood	IL-4	DCA+blood-MUFA%+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.122	0.858	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-4	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.33	0.858	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-4	3-(3-Hydroxyphenyl)propanoic acid+stool-20:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.33	0.858	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IL-4	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.304	0.858	no	no	no	no	no	no	DM-LS
TCA+stool	IL-4	TCA+stool-16:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.458	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool-18:1/20:3-PC+blood+20:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool-16:0-LPC+blood+GPC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool-nutriCA+stool-Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool+iso-LCA+stool+Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool-16:0/20:3-PC+blood-16:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool-16:0-LPC+blood-18:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool-18:0-LPA+blood-18:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool-18:1/20:3-PC+blood-CA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool-nutriCA+stool+CA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool+LCA+stool-ACA+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool-18:1-LPE+blood-22:6n3+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool-18:1/20:3-PC+blood+20:2+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool-18:1-LPC+blood+20:2+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool-16:0/20:3-PC+blood+20:2+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool-18:1/18:1-PC+blood+20:2+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool+EPA+blood+n3+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool-nutriCA+stool-n3+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool-18:1-LPE+blood-n3+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool-16:0/20:3-PC+blood+UFA%+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-4	HDCA+stool-18:1/18:1-PC+blood+UFA%+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	DM-LS
Lachnospira	IL-4	Lachnospira+Choline+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.279	0.858	no	no	no	no	no	no	DM-LS
Lachnospira	IL-4	Lachnospira+18:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.279	0.858	no	no	no	no	no	no	DM-LS
Lachnospira	IL-4	Lachnospira+20:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.279	0.858	no	no	no	no	no	no	DM-LS
Fusobacterium	IL-4	Fusobacterium+UFA%+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.628	0.858	no	no	no	no	no	no	DM-LS
Fusobacterium	IL-4	Fusobacterium+MUFA%+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.628	0.858	no	no	no	no	no	no	DM-LS
isobutyric acid C4+blood	IL-4	isobutyric acid C4+blood+MUFA%+blood-Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.0151	0.858	up	up	no	no	no	no	DM-LS
GCDCA+stool	IL-4	GCDCA+stool-Creatinine+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0471	0.858	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IL-4	GCDCA+stool+CA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0471	0.858	no	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-Acetic acid+stool-Cysteine+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-Propionic acid+stool-ACA+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+n3+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-Propionic acid+stool-MUFA%+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-Propionic acid+stool-UFA%+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-Acetic acid+stool-UFA%+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-Acetic acid+stool-Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-Propionic acid+stool+18:0/22:6-PE+blood+IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	DM-LS
Odoribacter	IL-4	Odoribacter+Choline+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.798	0.858	no	no	no	no	no	no	DM-LS
Odoribacter	IL-4	Odoribacter-L-2-Aminobutyric acid+blood-IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.798	0.858	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-4	Isobutyric acid+stool+Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_scfa	serum_cytokines	0.408	0.858	no	no	no	no	no	no	DM-LS
Lachnobacterium	IL-4	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.867	0.858	no	no	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-4	Kynurenic acid+stool-nutriCA+stool-Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.037	0.858	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-4	Kynurenic acid+stool+L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.037	0.858	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-4	Kynurenic acid+stool-UDCA+stool-18:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.037	0.858	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-4	Kynurenic acid+stool-UDCA+stool-20:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.037	0.858	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-4	Kynurenic acid+stool-nutriCA+stool+CA+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.037	0.858	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-4	Kynurenic acid+stool-nutriCA+stool-n3+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.037	0.858	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-4	Kynurenic acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.037	0.858	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-4	Kynurenic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.037	0.858	dn	dn	no	no	no	no	DM-LS
Anaerostipes	IL-4	Anaerostipes-Non-small cell lung cancer+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.568	0.858	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-4	Anaerostipes+TUDCA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.568	0.858	no	no	no	no	no	no	DM-LS
TUDCA+stool	IL-4	TUDCA+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.241	0.858	no	no	no	no	no	no	DM-LS
TUDCA+stool	IL-4	TUDCA+stool-UDCA+stool-20:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.241	0.858	no	no	no	no	no	no	DM-LS
TUDCA+stool	IL-4	TUDCA+stool-UDCA+stool-18:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.241	0.858	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-4	Isovaleric acid+stool+Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_scfa	serum_cytokines	0.343	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+18:0/20:2-PC+blood-18:0/22:6-PE+blood+IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+18:0/20:2-PC+blood+20:1+blood-IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+d18:1-20:0-SM+blood+GPC+blood+IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Arachidonic acid metabolism+Biosynthesis of amino acids-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Betaine+blood+UFA%+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Glutathione metabolism-Choline metabolism in cancer+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Arachidonic acid metabolism-Choline metabolism in cancer+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Glutathione metabolism-Cholinergic synapse+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Glutathione metabolism-mRNA surveillance pathway+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Arachidonic acid metabolism-mRNA surveillance pathway+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Glutathione metabolism-Non-small cell lung cancer+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Arachidonic acid metabolism-Non-small cell lung cancer+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+18:0/20:2-PC+blood+20:2+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Glutathione metabolism-Colorectal cancer+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Arachidonic acid metabolism-Colorectal cancer+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Arachidonic acid metabolism-Cell cycle+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Arachidonic acid metabolism+Choline+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Glutathione metabolism-ErbB signaling pathway+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Arachidonic acid metabolism-ErbB signaling pathway+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Glutathione metabolism-Phosphatidylinositol signaling system+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Arachidonic acid metabolism-Phosphatidylinositol signaling system+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella-18:0/22:6-PA+blood+22:6n3+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Glutathione metabolism-Gastric cancer+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Arachidonic acid metabolism-Gastric cancer+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Glutathione metabolism-Glioma+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Arachidonic acid metabolism-Glioma+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Glutathione metabolism-Signaling pathways regulating pluripotency of stem cells+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Arachidonic acid metabolism-Signaling pathways regulating pluripotency of stem cells+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Glutathione metabolism-Spliceosome+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Arachidonic acid metabolism-Spliceosome+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Betaine+blood-CA+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Glutathione metabolism-Long-term potentiation+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-4	Paraprevotella+Arachidonic acid metabolism-Long-term potentiation+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	DM-LS
iso-LCA+blood	IL-4	iso-LCA+blood-Sarcosine+blood-FGF basic+IL-17A+IL-4	Indirect	serum_bileacids	serum_cytokines	0.507	0.858	no	no	no	no	no	no	DM-LS
iso-LCA+blood	IL-4	iso-LCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.507	0.858	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	IL-4	Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.785	0.858	no	no	no	no	no	no	DM-LS
Gemmiger	IL-4	Gemmiger-18:1-LPC+blood+20:2+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-LS
Gemmiger	IL-4	Gemmiger+L-Phenylalanine+blood+n3+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-LS
Gemmiger	IL-4	Gemmiger-GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-LS
Gemmiger	IL-4	Gemmiger+DHA+blood-L-2-Aminobutyric acid+blood-IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-4	GDCA+stool-18:0/22:6-PE+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.656	0.858	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IL-4	Methanobrevibacter+n3+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.629	0.858	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IL-4	Methanobrevibacter+L-2-Aminobutyric acid+blood-IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.629	0.858	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	IL-4	L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.44	0.858	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	IL-4	L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_cometabolism	serum_cytokines	0.44	0.858	no	no	no	no	no	no	DM-LS
CDCA+stool	IL-4	CDCA+stool-Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	DM-LS
CDCA+stool	IL-4	CDCA+stool-20:5/18:0-PC+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	DM-LS
CA+stool	IL-4	CA+stool-Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	DM-LS
CA+stool	IL-4	CA+stool-18:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	DM-LS
CA+stool	IL-4	CA+stool-20:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	DM-LS
CA+stool	IL-4	CA+stool+CA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	DM-LS
Slackia	IL-4	Slackia+Platinum drug resistance+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.94	0.858	no	no	no	no	no	no	DM-LS
Slackia	IL-4	Slackia-Neutrophil extracellular trap formation-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.94	0.858	no	no	no	no	no	no	DM-LS
Slackia	IL-4	Slackia-Cysteine+blood-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.94	0.858	no	no	no	no	no	no	DM-LS
HDCA+blood	IL-4	HDCA+blood-Sarcosine+blood-FGF basic+IL-17A+IL-4	Indirect	serum_bileacids	serum_cytokines	0.483	0.858	no	no	no	no	no	no	DM-LS
HDCA+blood	IL-4	HDCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.483	0.858	no	no	no	no	no	no	DM-LS
UDCA+stool	IL-4	UDCA+stool-20:5/18:0-PC+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.266	0.858	no	no	no	no	no	no	DM-LS
UDCA+stool	IL-4	UDCA+stool-20:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.266	0.858	no	no	no	no	no	no	DM-LS
UDCA+stool	IL-4	UDCA+stool-18:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.266	0.858	no	no	no	no	no	no	DM-LS
TDCA+stool	IL-4	TDCA+stool+UDCA+stool-20:5/18:0-PC+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.963	0.858	no	no	no	no	no	no	DM-LS
TDCA+stool	IL-4	TDCA+stool+UDCA+stool-20:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.963	0.858	no	no	no	no	no	no	DM-LS
TDCA+stool	IL-4	TDCA+stool+UDCA+stool-18:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.963	0.858	no	no	no	no	no	no	DM-LS
nutriCA+stool	IL-4	nutriCA+stool+CA+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.481	0.858	no	no	no	no	no	no	DM-LS
nutriCA+stool	IL-4	nutriCA+stool-n3+blood-Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.481	0.858	no	no	no	no	no	no	DM-LS
nutriCA+stool	IL-4	nutriCA+stool-Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.481	0.858	no	no	no	no	no	no	DM-LS
GDCA+blood	IL-4	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.632	0.858	no	no	no	no	no	no	DM-LS
acetic acid C2+blood	IL-4	acetic acid C2+blood+total_blood_scfa+blood+TUDCA+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.000193	0.858	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	IL-4	acetic acid C2+blood-Sarcosine+blood-TUDCA+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.000193	0.858	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	IL-4	acetic acid C2+blood+capric acid C6+blood+TUDCA+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.000193	0.858	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	IL-4	acetic acid C2+blood+capric acid C6+blood+MUFA%+blood-Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.000193	0.858	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	IL-4	acetic acid C2+blood-d18:1-14:1-SM+blood-MUFA%+blood-Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.000193	0.858	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	IL-4	acetic acid C2+blood+capric acid C6+blood+UFA%+blood-Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.000193	0.858	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	IL-4	acetic acid C2+blood-d18:1-14:1-SM+blood-UFA%+blood-Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.000193	0.858	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	IL-4	acetic acid C2+blood-L-Alanine+blood-FGF basic+IL-17A+IL-4	Indirect	serum_scfa	serum_cytokines	0.000193	0.858	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	IL-4	acetic acid C2+blood-Sarcosine+blood-FGF basic+IL-17A+IL-4	Indirect	serum_scfa	serum_cytokines	0.000193	0.858	up	dn	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	IL-4	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.117	0.858	no	no	no	no	no	no	DM-LS
Adlercreutzia	IL-4	Adlercreutzia-16:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.548	0.858	no	no	no	no	no	no	DM-LS
Clostridium	IL-4	Clostridium-20:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-4	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+IL-1ra-IL-4	Indirect	stool_bileacids	serum_cytokines	0.48	0.858	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-4	12-ketoDCA+blood-20:0-LPC+blood+20:1+blood-IL-1ra-IL-4	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-4	12-ketoDCA+blood-8-HETE+blood-ACA+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-4	12-ketoDCA+blood-20:3-LPE+blood-22:6n3+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-4	12-ketoDCA+blood-20:3-LPE+blood+Choline+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-4	12-ketoDCA+blood-L-Lysine+blood+UFA%+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-4	12-ketoDCA+blood-L-Arginine+blood+UFA%+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-4	12-ketoDCA+blood-20:3-LPE+blood-n3+blood-Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-4	Butyricicoccus+Allograft rejection-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.852	0.858	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-4	Butyricicoccus+Viral myocarditis-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.852	0.858	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-4	Butyricicoccus+Cell adhesion molecules-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.852	0.858	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-4	Butyricicoccus+Type I diabetes mellitus-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.852	0.858	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-4	Butyricicoccus+Graft-versus-host disease-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.852	0.858	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-4	Butyricicoccus+Phagosome-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.852	0.858	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-4	Butyricicoccus+Autoimmune thyroid disease-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.852	0.858	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-4	Butyricicoccus-Phenylacetic acid+stool-IL-1ra-IL-4	Indirect	Genus	serum_cytokines	0.852	0.858	no	no	no	no	no	no	DM-LS
Blautia	TNF-a	Blautia-20:5/18:0-PC+blood-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	DM-LS
Blautia	TNF-a	Blautia-20:5/18:0-PC+blood-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	DM-LS
Blautia	TNF-a	Blautia+GCA+blood+FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	DM-LS
Blautia	TNF-a	Blautia-20:5/18:0-PC+blood-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	DM-LS
Blautia	TNF-a	Blautia-16:0/18:2-PC+blood+20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	DM-LS
Blautia	TNF-a	Blautia-18:1/16:0-PC+blood+20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	DM-LS
Blautia	TNF-a	Blautia-18:0/22:6-PC+blood+20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	DM-LS
Blautia	TNF-a	Blautia-12-ketoDCA+stool+18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	DM-LS
Blautia	TNF-a	Blautia-18:0/22:6-PC+blood+18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	DM-LS
Blautia	TNF-a	Blautia-16:0/22:6-PC+blood+18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	DM-LS
Blautia	TNF-a	Blautia-16:0/18:2-PC+blood+18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	DM-LS
Parabacteroides	TNF-a	Parabacteroides-Glucagon signaling pathway+Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-LS
Parabacteroides	TNF-a	Parabacteroides-Spliceosome+Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-LS
Parabacteroides	TNF-a	Parabacteroides+Choline+blood-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-LS
Parabacteroides	TNF-a	Parabacteroides-Glucagon signaling pathway+Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-LS
Parabacteroides	TNF-a	Parabacteroides-Spliceosome+Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-LS
Parabacteroides	TNF-a	Parabacteroides+Choline+blood-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-LS
Parabacteroides	TNF-a	Parabacteroides-EGFR tyrosine kinase inhibitor resistance+Proteasome-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-LS
Parabacteroides	TNF-a	Parabacteroides-Central carbon metabolism in cancer+18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-LS
Parabacteroides	TNF-a	Parabacteroides-TCA+stool-16:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-LS
Parabacteroides	TNF-a	Parabacteroides-GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-LS
Parabacteroides	TNF-a	Parabacteroides-Insulin signaling pathway+L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-LS
Parabacteroides	TNF-a	Parabacteroides-15-HETE+blood-20:1+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-LS
Parabacteroides	TNF-a	Parabacteroides+20:0+blood-FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-LS
Parabacteroides	TNF-a	Parabacteroides-Glucagon signaling pathway+Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-LS
Parabacteroides	TNF-a	Parabacteroides-Spliceosome+Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-LS
Parabacteroides	TNF-a	Parabacteroides+Choline+blood-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	DM-LS
Dorea	TNF-a	Dorea-18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	DM-LS
Faecalibacterium	TNF-a	Faecalibacterium-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.0039	0.613	no	dn	dn	no	no	no	DM-LS
TUDCA+blood	TNF-a	TUDCA+blood+Eotaxin+IL-4+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.0282	0.613	no	no	dn	no	no	no	DM-LS
TUDCA+blood	TNF-a	TUDCA+blood+Eotaxin-GM-CSF-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.0282	0.613	no	no	dn	no	no	no	DM-LS
TUDCA+blood	TNF-a	TUDCA+blood+Eotaxin+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.0282	0.613	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	TNF-a	isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF-TNF-a	Indirect	serum_scfa	serum_cytokines	0.0458	0.613	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	TNF-a	isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-4+TNF-a	Indirect	serum_scfa	serum_cytokines	0.0458	0.613	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	TNF-a	isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-17A+TNF-a	Indirect	serum_scfa	serum_cytokines	0.0458	0.613	no	no	dn	no	no	no	DM-LS
Bacteroides	TNF-a	Bacteroides+n3+blood-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	DM-LS
Bacteroides	TNF-a	Bacteroides+22:6n3+blood-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	DM-LS
Bacteroides	TNF-a	Bacteroides+n3+blood-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	DM-LS
Bacteroides	TNF-a	Bacteroides+22:6n3+blood-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	DM-LS
Bacteroides	TNF-a	Bacteroides-18:2/20:4-PC+blood+20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	DM-LS
Bacteroides	TNF-a	Bacteroides+3-(3-Hydroxyphenyl)propanoic acid+stool-20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	DM-LS
Bacteroides	TNF-a	Bacteroides+3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	DM-LS
Bacteroides	TNF-a	Bacteroides-GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	DM-LS
Bacteroides	TNF-a	Bacteroides+n3+blood-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	DM-LS
Bacteroides	TNF-a	Bacteroides+22:6n3+blood-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	DM-LS
Propionic acid+stool	TNF-a	Propionic acid+stool+18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	stool_scfa	serum_cytokines	0.0436	0.613	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	TNF-a	Propionic acid+stool+16:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_scfa	serum_cytokines	0.0436	0.613	dn	no	up	no	no	no	DM-LS
[Ruminococcus]	TNF-a	[Ruminococcus]-FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	DM-LS
GUDCA+blood	TNF-a	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.0766	0.613	no	no	dn	no	no	no	DM-LS
GUDCA+blood	TNF-a	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.0766	0.613	no	no	dn	no	no	no	DM-LS
GUDCA+blood	TNF-a	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-4+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.0766	0.613	no	no	dn	no	no	no	DM-LS
Acetic acid+stool	TNF-a	Acetic acid+stool-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_scfa	serum_cytokines	0.0656	0.613	dn	no	no	no	no	no	DM-LS
Alistipes	TNF-a	Alistipes+12-ketoDCA+stool+18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.0114	0.613	no	up	no	no	no	no	DM-LS
Butyricimonas	TNF-a	Butyricimonas+20:5/18:0-PC+blood-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	DM-LS
Butyricimonas	TNF-a	Butyricimonas+20:5/18:0-PC+blood-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	DM-LS
Butyricimonas	TNF-a	Butyricimonas-Prion disease-18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	DM-LS
Butyricimonas	TNF-a	Butyricimonas-Cardiac muscle contraction-18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	DM-LS
Butyricimonas	TNF-a	Butyricimonas-Prion disease-20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	DM-LS
Butyricimonas	TNF-a	Butyricimonas-Cardiac muscle contraction-20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	DM-LS
Butyricimonas	TNF-a	Butyricimonas-GCA+blood+FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	DM-LS
Butyricimonas	TNF-a	Butyricimonas+20:5/18:0-PC+blood-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Signaling pathways regulating pluripotency of stem cells+Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Colorectal cancer+Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Glioma+Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Long-term potentiation+Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Choline metabolism in cancer+Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Gastric cancer+Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-ErbB signaling pathway+Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Phosphatidylinositol signaling system+Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Hepatitis B-FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Insulin resistance-FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Prostate cancer-FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-NF-kappa B signaling pathway-FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Central carbon metabolism in cancer+18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Insulin resistance+20:1+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-DHA+blood-L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-MAPK signaling pathway-Salivary secretion+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Wnt signaling pathway-Salivary secretion+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-RNA degradation-Salivary secretion+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Phosphatidylinositol signaling system-Salivary secretion+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Hepatitis B+GPC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Long-term potentiation-20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Signaling pathways regulating pluripotency of stem cells+Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Colorectal cancer+Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Glioma+Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Long-term potentiation+Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Choline metabolism in cancer+Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Gastric cancer+Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-ErbB signaling pathway+Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Phosphatidylinositol signaling system+Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Signaling pathways regulating pluripotency of stem cells+Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Colorectal cancer+Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Glioma+Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Long-term potentiation+Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Choline metabolism in cancer+Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Gastric cancer+Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-ErbB signaling pathway+Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
Collinsella	TNF-a	Collinsella-Phosphatidylinositol signaling system+Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	TNF-a	total_blood_scfa+blood+TUDCA+blood+Eotaxin+IL-4+TNF-a	Indirect	serum_scfa	serum_cytokines	0.168	0.613	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	TNF-a	total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF-TNF-a	Indirect	serum_scfa	serum_cytokines	0.168	0.613	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	TNF-a	total_blood_scfa+blood+TUDCA+blood+Eotaxin+IL-17A+TNF-a	Indirect	serum_scfa	serum_cytokines	0.168	0.613	no	no	no	no	no	no	DM-LS
[Eubacterium]	TNF-a	[Eubacterium]-Viral myocarditis-L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.0692	0.613	no	no	no	no	no	no	DM-LS
[Eubacterium]	TNF-a	[Eubacterium]-Viral myocarditis-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.0692	0.613	no	no	no	no	no	no	DM-LS
[Eubacterium]	TNF-a	[Eubacterium]-Viral myocarditis-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.0692	0.613	no	no	no	no	no	no	DM-LS
[Eubacterium]	TNF-a	[Eubacterium]-Pathogenic Escherichia coli infection-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.0692	0.613	no	no	no	no	no	no	DM-LS
[Eubacterium]	TNF-a	[Eubacterium]-Phagosome-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.0692	0.613	no	no	no	no	no	no	DM-LS
[Eubacterium]	TNF-a	[Eubacterium]-Viral myocarditis-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.0692	0.613	no	no	no	no	no	no	DM-LS
[Eubacterium]	TNF-a	[Eubacterium]-Pathogenic Escherichia coli infection-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.0692	0.613	no	no	no	no	no	no	DM-LS
[Eubacterium]	TNF-a	[Eubacterium]-Phagosome-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.0692	0.613	no	no	no	no	no	no	DM-LS
[Eubacterium]	TNF-a	[Eubacterium]-Salmonella infection+FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.0692	0.613	no	no	no	no	no	no	DM-LS
[Eubacterium]	TNF-a	[Eubacterium]-Viral myocarditis-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.0692	0.613	no	no	no	no	no	no	DM-LS
[Eubacterium]	TNF-a	[Eubacterium]-Pathogenic Escherichia coli infection-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.0692	0.613	no	no	no	no	no	no	DM-LS
[Eubacterium]	TNF-a	[Eubacterium]-Phagosome-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.0692	0.613	no	no	no	no	no	no	DM-LS
LCA+stool	TNF-a	LCA+stool-ACA+blood-Eotaxin+IL-4+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.314	0.613	no	no	no	no	no	no	DM-LS
LCA+stool	TNF-a	LCA+stool-ACA+blood-Eotaxin+IL-17A+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.314	0.613	no	no	no	no	no	no	DM-LS
LCA+stool	TNF-a	LCA+stool-ACA+blood-Eotaxin-GM-CSF-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.314	0.613	no	no	no	no	no	no	DM-LS
LCA+stool	TNF-a	LCA+stool-Cystine+blood+L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.314	0.613	no	no	no	no	no	no	DM-LS
LCA+stool	TNF-a	LCA+stool-TCA+stool-16:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.314	0.613	no	no	no	no	no	no	DM-LS
LCA+stool	TNF-a	LCA+stool-UDCA+stool-20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.314	0.613	no	no	no	no	no	no	DM-LS
LCA+stool	TNF-a	LCA+stool-UDCA+stool-18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.314	0.613	no	no	no	no	no	no	DM-LS
LCA+stool	TNF-a	LCA+stool-nutriCA+stool-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.314	0.613	no	no	no	no	no	no	DM-LS
Akkermansia	TNF-a	Akkermansia+18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	DM-LS
Bifidobacterium	TNF-a	Bifidobacterium-FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.105	0.613	no	dn	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Type I diabetes mellitus-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Endocytosis-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Allograft rejection-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Graft-versus-host disease-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Cell adhesion molecules-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Autoimmune thyroid disease-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Cell adhesion molecules-L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Type I diabetes mellitus-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Endocytosis-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Allograft rejection-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+22:6n3+blood-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Graft-versus-host disease-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Phagosome-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Cell adhesion molecules-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Autoimmune thyroid disease-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Type I diabetes mellitus-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Endocytosis-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Allograft rejection-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+22:6n3+blood-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Graft-versus-host disease-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Phagosome-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Cell adhesion molecules-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Autoimmune thyroid disease-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Type I diabetes mellitus-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Endocytosis-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Allograft rejection-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+22:6n3+blood-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Graft-versus-host disease-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Phagosome-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Cell adhesion molecules-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
Ruminococcus	TNF-a	Ruminococcus+Autoimmune thyroid disease-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	DM-LS
GCDCA+blood	TNF-a	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.31	0.613	no	no	no	no	no	no	DM-LS
GCDCA+blood	TNF-a	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.31	0.613	no	no	no	no	no	no	DM-LS
GCDCA+blood	TNF-a	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.31	0.613	no	no	no	no	no	no	DM-LS
Succinivibrio	TNF-a	Succinivibrio-L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.138	0.613	no	no	no	no	no	no	DM-LS
Succinivibrio	TNF-a	Succinivibrio-L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.138	0.613	no	no	no	no	no	no	DM-LS
ACA+blood	TNF-a	ACA+blood-Eotaxin+IL-4+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.338	0.613	no	no	no	no	no	no	DM-LS
ACA+blood	TNF-a	ACA+blood-Eotaxin+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.338	0.613	no	no	no	no	no	no	DM-LS
ACA+blood	TNF-a	ACA+blood-Eotaxin-GM-CSF-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.338	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool-UFA%+blood-Eotaxin-GM-CSF-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool-ACA+blood-Eotaxin-GM-CSF-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool-18:1/18:0-PC+blood+20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool-18:0/18:2-PC+blood+20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool-GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool-Cystine+blood+L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool+18:0/18:0-PS+blood+18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool-GDCA+stool-18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool+16:0/18:0-PS+blood+18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool+Propionic acid+stool+18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool+18:0/18:0-PS+blood-18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool+16:0/18:0-PS+blood-18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool-18:0/18:2-PC+blood+18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool+iso-LCA+stool+Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool-16:0/20:3-PC+blood-16:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool+Propionic acid+stool+16:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool-TCA+stool-16:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool-UFA%+blood-Eotaxin+IL-4+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool-ACA+blood-Eotaxin+IL-4+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool-UFA%+blood-Eotaxin+IL-17A+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
DCA+stool	TNF-a	DCA+stool-ACA+blood-Eotaxin+IL-17A+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	DM-LS
Butyric acid+stool	TNF-a	Butyric acid+stool-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_scfa	serum_cytokines	0.102	0.613	dn	no	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	TNF-a	4-hydroxybenzoic acid+stool-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.613	no	dn	no	no	no	no	DM-LS
GCA+blood	TNF-a	GCA+blood+FGF basic+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.16	0.613	no	no	no	no	no	no	DM-LS
ACA+stool	TNF-a	ACA+stool+GPC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.417	0.613	no	no	no	no	no	no	DM-LS
CDCA+blood	TNF-a	CDCA+blood-Cysteine+blood+L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.506	0.613	no	no	no	no	no	no	DM-LS
CDCA+blood	TNF-a	CDCA+blood-MUFA%+blood-Eotaxin-GM-CSF-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.506	0.613	no	no	no	no	no	no	DM-LS
CDCA+blood	TNF-a	CDCA+blood-Cysteine+blood-Eotaxin-GM-CSF-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.506	0.613	no	no	no	no	no	no	DM-LS
CDCA+blood	TNF-a	CDCA+blood-MUFA%+blood-Eotaxin+IL-4+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.506	0.613	no	no	no	no	no	no	DM-LS
CDCA+blood	TNF-a	CDCA+blood-Cysteine+blood-Eotaxin+IL-4+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.506	0.613	no	no	no	no	no	no	DM-LS
CDCA+blood	TNF-a	CDCA+blood-MUFA%+blood-Eotaxin+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.506	0.613	no	no	no	no	no	no	DM-LS
CDCA+blood	TNF-a	CDCA+blood-Cysteine+blood-Eotaxin+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.506	0.613	no	no	no	no	no	no	DM-LS
capric acid C6+blood	TNF-a	capric acid C6+blood+UFA%+blood-Eotaxin+IL-17A+TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	DM-LS
capric acid C6+blood	TNF-a	capric acid C6+blood+TUDCA+blood+Eotaxin+IL-17A+TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	DM-LS
capric acid C6+blood	TNF-a	capric acid C6+blood+MUFA%+blood-Eotaxin+IL-17A+TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	DM-LS
capric acid C6+blood	TNF-a	capric acid C6+blood-Sarcosine+blood-FGF basic+IL-17A+TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	DM-LS
capric acid C6+blood	TNF-a	capric acid C6+blood-L-Alanine+blood-FGF basic+IL-17A+TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	DM-LS
capric acid C6+blood	TNF-a	capric acid C6+blood+UFA%+blood-Eotaxin+IL-4+TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	DM-LS
capric acid C6+blood	TNF-a	capric acid C6+blood+TUDCA+blood+Eotaxin+IL-4+TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	DM-LS
capric acid C6+blood	TNF-a	capric acid C6+blood+MUFA%+blood-Eotaxin+IL-4+TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	DM-LS
capric acid C6+blood	TNF-a	capric acid C6+blood+UFA%+blood-Eotaxin-GM-CSF-TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	DM-LS
capric acid C6+blood	TNF-a	capric acid C6+blood+TUDCA+blood+Eotaxin-GM-CSF-TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	DM-LS
capric acid C6+blood	TNF-a	capric acid C6+blood+MUFA%+blood-Eotaxin-GM-CSF-TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	DM-LS
Pyramidobacter	TNF-a	Pyramidobacter+Insulin resistance-FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.45	0.613	no	no	no	no	no	no	DM-LS
Pyramidobacter	TNF-a	"Pyramidobacter+Parathyroid hormone synthesis, secretion and action-FGF basic+IL-17A+TNF-a"	Indirect	Genus	serum_cytokines	0.45	0.613	no	no	no	no	no	no	DM-LS
Pyramidobacter	TNF-a	Pyramidobacter-Carbon metabolism+FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.45	0.613	no	no	no	no	no	no	DM-LS
Pyramidobacter	TNF-a	Pyramidobacter+Small cell lung cancer-FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.45	0.613	no	no	no	no	no	no	DM-LS
Pyramidobacter	TNF-a	Pyramidobacter+Prostate cancer-FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.45	0.613	no	no	no	no	no	no	DM-LS
Pyramidobacter	TNF-a	Pyramidobacter-Carbon metabolism-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.45	0.613	no	no	no	no	no	no	DM-LS
Pyramidobacter	TNF-a	Pyramidobacter+Glucagon signaling pathway+Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.45	0.613	no	no	no	no	no	no	DM-LS
Pyramidobacter	TNF-a	Pyramidobacter-Carbon metabolism-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.45	0.613	no	no	no	no	no	no	DM-LS
Pyramidobacter	TNF-a	Pyramidobacter+Glucagon signaling pathway+Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.45	0.613	no	no	no	no	no	no	DM-LS
Pyramidobacter	TNF-a	Pyramidobacter-Carbon metabolism-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.45	0.613	no	no	no	no	no	no	DM-LS
Pyramidobacter	TNF-a	Pyramidobacter+Glucagon signaling pathway+Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.45	0.613	no	no	no	no	no	no	DM-LS
Pyramidobacter	TNF-a	Pyramidobacter+Insulin resistance+20:1+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.45	0.613	no	no	no	no	no	no	DM-LS
Pyramidobacter	TNF-a	"Pyramidobacter+Parathyroid hormone synthesis, secretion and action+Salivary secretion+IL-1ra-TNF-a"	Indirect	Genus	serum_cytokines	0.45	0.613	no	no	no	no	no	no	DM-LS
Pyramidobacter	TNF-a	Pyramidobacter-Carbon metabolism+18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.45	0.613	no	no	no	no	no	no	DM-LS
Pyramidobacter	TNF-a	Pyramidobacter+Pathways in cancer+Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.45	0.613	no	no	no	no	no	no	DM-LS
Prevotella	TNF-a	Prevotella-Proteasome-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.287	0.613	no	no	no	no	no	no	DM-LS
TCA+blood	TNF-a	TCA+blood+FGF basic+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.339	0.613	no	no	no	no	no	no	DM-LS
iso-DCA+blood	TNF-a	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.38	0.613	no	no	no	no	no	no	DM-LS
iso-DCA+blood	TNF-a	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.38	0.613	no	no	no	no	no	no	DM-LS
iso-DCA+blood	TNF-a	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.38	0.613	no	no	no	no	no	no	DM-LS
iso-DCA+blood	TNF-a	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin-GM-CSF-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.38	0.613	no	no	no	no	no	no	DM-LS
iso-DCA+blood	TNF-a	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin-GM-CSF-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.38	0.613	no	no	no	no	no	no	DM-LS
iso-DCA+blood	TNF-a	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin-GM-CSF-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.38	0.613	no	no	no	no	no	no	DM-LS
iso-DCA+blood	TNF-a	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin+IL-4+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.38	0.613	no	no	no	no	no	no	DM-LS
iso-DCA+blood	TNF-a	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin+IL-4+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.38	0.613	no	no	no	no	no	no	DM-LS
iso-DCA+blood	TNF-a	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin+IL-4+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.38	0.613	no	no	no	no	no	no	DM-LS
HCA+stool	TNF-a	HCA+stool-18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.155	0.613	no	no	no	no	no	no	DM-LS
HCA+stool	TNF-a	HCA+stool-GPC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.155	0.613	no	no	no	no	no	no	DM-LS
Roseburia	TNF-a	Roseburia-20:1+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.495	0.613	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	TNF-a	12-ketoDCA+stool+18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.505	0.613	no	no	no	no	no	no	DM-LS
GLCA+blood	TNF-a	GLCA+blood-Sarcosine+blood-FGF basic+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.319	0.613	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	TNF-a	L-Tryptophan+stool+Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.557	0.613	no	no	no	no	no	no	DM-LS
CA+blood	TNF-a	CA+blood+Eotaxin-GM-CSF-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.606	0.613	no	no	no	no	no	no	DM-LS
CA+blood	TNF-a	CA+blood+Eotaxin+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.606	0.613	no	no	no	no	no	no	DM-LS
CA+blood	TNF-a	CA+blood+Eotaxin+IL-4+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.606	0.613	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	TNF-a	L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.398	0.613	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	TNF-a	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin+IL-17A+TNF-a	Indirect	serum_scfa	serum_cytokines	0.407	0.613	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	TNF-a	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF-TNF-a	Indirect	serum_scfa	serum_cytokines	0.407	0.613	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	TNF-a	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin+IL-4+TNF-a	Indirect	serum_scfa	serum_cytokines	0.407	0.613	no	no	no	no	no	no	DM-LS
GCA+stool	TNF-a	GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0809	0.613	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	TNF-a	T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.478	0.613	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	TNF-a	T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.478	0.613	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	TNF-a	T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.478	0.613	no	no	no	no	no	no	DM-LS
Coprococcus	TNF-a	Coprococcus-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.612	0.613	no	no	no	no	no	no	DM-LS
Coprococcus	TNF-a	Coprococcus-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.612	0.613	no	no	no	no	no	no	DM-LS
Coprococcus	TNF-a	Coprococcus-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.612	0.613	no	no	no	no	no	no	DM-LS
Oscillospira	TNF-a	Oscillospira-Adrenergic signaling in cardiomyocytes+Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-LS
Oscillospira	TNF-a	Oscillospira+Peroxisome-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-LS
Oscillospira	TNF-a	Oscillospira+Peroxisome+18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-LS
Oscillospira	TNF-a	Oscillospira+Peroxisome+18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-LS
Oscillospira	TNF-a	Oscillospira-Alzheimer disease-18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-LS
Oscillospira	TNF-a	Oscillospira+Peroxisome+20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-LS
Oscillospira	TNF-a	Oscillospira-Alzheimer disease-20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-LS
Oscillospira	TNF-a	Oscillospira-CDCA+stool-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-LS
Oscillospira	TNF-a	Oscillospira-nutriCA+stool-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-LS
Oscillospira	TNF-a	Oscillospira-4-hydroxybenzoic acid+stool-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-LS
Oscillospira	TNF-a	Oscillospira-Adrenergic signaling in cardiomyocytes+Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-LS
Oscillospira	TNF-a	Oscillospira+Peroxisome-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-LS
Oscillospira	TNF-a	Oscillospira-Adrenergic signaling in cardiomyocytes+Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-LS
Oscillospira	TNF-a	Oscillospira+Peroxisome-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	DM-LS
HCA+blood	TNF-a	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin-GM-CSF-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.544	0.613	no	no	no	no	no	no	DM-LS
HCA+blood	TNF-a	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.544	0.613	no	no	no	no	no	no	DM-LS
HCA+blood	TNF-a	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin+IL-4+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.544	0.613	no	no	no	no	no	no	DM-LS
iso-LCA+stool	TNF-a	iso-LCA+stool+Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.72	0.613	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	TNF-a	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin-GM-CSF-TNF-a	Indirect	serum_scfa	serum_cytokines	0.262	0.613	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	TNF-a	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin+IL-17A+TNF-a	Indirect	serum_scfa	serum_cytokines	0.262	0.613	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	TNF-a	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin+IL-4+TNF-a	Indirect	serum_scfa	serum_cytokines	0.262	0.613	no	no	no	no	no	no	DM-LS
DCA+blood	TNF-a	DCA+blood-MUFA%+blood-Eotaxin+IL-4+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.122	0.613	no	no	no	no	no	no	DM-LS
DCA+blood	TNF-a	DCA+blood-MUFA%+blood-Eotaxin+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.122	0.613	no	no	no	no	no	no	DM-LS
DCA+blood	TNF-a	DCA+blood-TCA+blood+FGF basic+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.122	0.613	no	no	no	no	no	no	DM-LS
DCA+blood	TNF-a	DCA+blood-MUFA%+blood-Eotaxin-GM-CSF-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.122	0.613	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	TNF-a	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.33	0.613	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	TNF-a	3-(3-Hydroxyphenyl)propanoic acid+stool-20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.33	0.613	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	TNF-a	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.613	no	no	no	no	no	no	DM-LS
TCA+stool	TNF-a	TCA+stool-16:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.458	0.613	no	no	no	no	no	no	DM-LS
HDCA+stool	TNF-a	HDCA+stool-18:1/20:3-PC+blood+20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.176	0.613	no	no	no	no	no	no	DM-LS
HDCA+stool	TNF-a	HDCA+stool-16:0-LPC+blood+GPC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.176	0.613	no	no	no	no	no	no	DM-LS
HDCA+stool	TNF-a	HDCA+stool-nutriCA+stool-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.176	0.613	no	no	no	no	no	no	DM-LS
HDCA+stool	TNF-a	HDCA+stool+iso-LCA+stool+Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.176	0.613	no	no	no	no	no	no	DM-LS
HDCA+stool	TNF-a	HDCA+stool-16:0/20:3-PC+blood-16:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.176	0.613	no	no	no	no	no	no	DM-LS
HDCA+stool	TNF-a	HDCA+stool-16:0-LPC+blood-18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.176	0.613	no	no	no	no	no	no	DM-LS
HDCA+stool	TNF-a	HDCA+stool-18:0-LPA+blood-18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.176	0.613	no	no	no	no	no	no	DM-LS
Lachnospira	TNF-a	Lachnospira+18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-LS
Lachnospira	TNF-a	Lachnospira+20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	DM-LS
Fusobacterium	TNF-a	Fusobacterium+16:0/20:3-PC+blood-16:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.628	0.613	no	no	no	no	no	no	DM-LS
Fusobacterium	TNF-a	Fusobacterium+nutriCA+stool-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.628	0.613	no	no	no	no	no	no	DM-LS
Fusobacterium	TNF-a	Fusobacterium+UFA%+blood-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.628	0.613	no	no	no	no	no	no	DM-LS
Fusobacterium	TNF-a	Fusobacterium+MUFA%+blood-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.628	0.613	no	no	no	no	no	no	DM-LS
Fusobacterium	TNF-a	Fusobacterium+UFA%+blood-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.628	0.613	no	no	no	no	no	no	DM-LS
Fusobacterium	TNF-a	Fusobacterium+MUFA%+blood-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.628	0.613	no	no	no	no	no	no	DM-LS
Fusobacterium	TNF-a	Fusobacterium+UFA%+blood-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.628	0.613	no	no	no	no	no	no	DM-LS
Fusobacterium	TNF-a	Fusobacterium+MUFA%+blood-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.628	0.613	no	no	no	no	no	no	DM-LS
isobutyric acid C4+blood	TNF-a	isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF-TNF-a	Indirect	serum_scfa	serum_cytokines	0.0151	0.613	up	up	no	no	no	no	DM-LS
isobutyric acid C4+blood	TNF-a	isobutyric acid C4+blood+MUFA%+blood-Eotaxin+IL-17A+TNF-a	Indirect	serum_scfa	serum_cytokines	0.0151	0.613	up	up	no	no	no	no	DM-LS
isobutyric acid C4+blood	TNF-a	isobutyric acid C4+blood+MUFA%+blood-Eotaxin+IL-4+TNF-a	Indirect	serum_scfa	serum_cytokines	0.0151	0.613	up	up	no	no	no	no	DM-LS
GCDCA+stool	TNF-a	GCDCA+stool-Creatinine+blood-Eotaxin-GM-CSF-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-LS
GCDCA+stool	TNF-a	GCDCA+stool+CA+blood+Eotaxin-GM-CSF-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-LS
GCDCA+stool	TNF-a	GCDCA+stool+TCA+stool-16:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-LS
GCDCA+stool	TNF-a	GCDCA+stool+18:0/18:0-PC+blood+20:1+blood-IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-LS
GCDCA+stool	TNF-a	GCDCA+stool+18:0/18:1-PC+blood+20:1+blood-IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-LS
GCDCA+stool	TNF-a	GCDCA+stool+18:0/18:0-PC+blood+L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-LS
GCDCA+stool	TNF-a	GCDCA+stool+18:0/18:1-PC+blood+L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-LS
GCDCA+stool	TNF-a	GCDCA+stool+GDCA+stool-18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-LS
GCDCA+stool	TNF-a	GCDCA+stool-Creatinine+blood-Eotaxin+IL-4+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-LS
GCDCA+stool	TNF-a	GCDCA+stool+CA+blood+Eotaxin+IL-4+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-LS
GCDCA+stool	TNF-a	GCDCA+stool-Creatinine+blood-Eotaxin+IL-17A+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-LS
GCDCA+stool	TNF-a	GCDCA+stool+CA+blood+Eotaxin+IL-17A+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	TNF-a	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.613	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	TNF-a	5-Hydroxytryptamine+stool+L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.613	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	TNF-a	5-Hydroxytryptamine+stool-Acetic acid+stool-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.613	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	TNF-a	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.613	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	TNF-a	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.613	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	TNF-a	5-Hydroxytryptamine+stool-Propionic acid+stool+18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.613	dn	dn	no	no	no	no	DM-LS
Odoribacter	TNF-a	Odoribacter+IL-8-TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	TNF-a	Isobutyric acid+stool+Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_scfa	serum_cytokines	0.408	0.613	no	no	no	no	no	no	DM-LS
Lachnobacterium	TNF-a	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.867	0.613	no	no	no	no	no	no	DM-LS
Lachnobacterium	TNF-a	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.867	0.613	no	no	no	no	no	no	DM-LS
Lachnobacterium	TNF-a	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.867	0.613	no	no	no	no	no	no	DM-LS
Kynurenic acid+stool	TNF-a	Kynurenic acid+stool-nutriCA+stool-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.613	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	TNF-a	Kynurenic acid+stool+L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.613	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	TNF-a	Kynurenic acid+stool-UDCA+stool-18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.613	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	TNF-a	Kynurenic acid+stool-UDCA+stool-20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.613	dn	dn	no	no	no	no	DM-LS
Anaerostipes	TNF-a	Anaerostipes+15-HETE+blood-20:1+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	DM-LS
Anaerostipes	TNF-a	Anaerostipes-Insulin resistance+20:1+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	DM-LS
Anaerostipes	TNF-a	Anaerostipes-3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	DM-LS
Anaerostipes	TNF-a	Anaerostipes-Hepatitis B+GPC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	DM-LS
Anaerostipes	TNF-a	Anaerostipes-3-(3-Hydroxyphenyl)propanoic acid+stool-20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	DM-LS
Anaerostipes	TNF-a	Anaerostipes-Non-small cell lung cancer+Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	DM-LS
Anaerostipes	TNF-a	Anaerostipes+TUDCA+blood+Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	DM-LS
Anaerostipes	TNF-a	Anaerostipes-Hepatitis B-FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	DM-LS
Anaerostipes	TNF-a	Anaerostipes-Chronic myeloid leukemia-FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	DM-LS
Anaerostipes	TNF-a	Anaerostipes-Insulin resistance-FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	DM-LS
Anaerostipes	TNF-a	Anaerostipes-Prostate cancer-FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	DM-LS
Anaerostipes	TNF-a	Anaerostipes-Non-small cell lung cancer+Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	DM-LS
Anaerostipes	TNF-a	Anaerostipes+TUDCA+blood+Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	DM-LS
Anaerostipes	TNF-a	Anaerostipes-Non-small cell lung cancer+Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	DM-LS
Anaerostipes	TNF-a	Anaerostipes+TUDCA+blood+Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	DM-LS
TUDCA+stool	TNF-a	TUDCA+stool-UDCA+stool-20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.241	0.613	no	no	no	no	no	no	DM-LS
TUDCA+stool	TNF-a	TUDCA+stool-UDCA+stool-18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.241	0.613	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool+Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	DM-LS
Paraprevotella	TNF-a	Paraprevotella+18:0/20:2-PC+blood-18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.118	0.613	no	no	no	no	no	no	DM-LS
Paraprevotella	TNF-a	Paraprevotella+18:0/20:2-PC+blood+20:1+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.118	0.613	no	no	no	no	no	no	DM-LS
Paraprevotella	TNF-a	Paraprevotella+d18:1-20:0-SM+blood+GPC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.118	0.613	no	no	no	no	no	no	DM-LS
iso-LCA+blood	TNF-a	iso-LCA+blood-Sarcosine+blood-FGF basic+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.507	0.613	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	TNF-a	Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.785	0.613	no	no	no	no	no	no	DM-LS
Gemmiger	TNF-a	Gemmiger-GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.595	0.613	no	no	no	no	no	no	DM-LS
Gemmiger	TNF-a	Gemmiger+DHA+blood-L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.595	0.613	no	no	no	no	no	no	DM-LS
GDCA+stool	TNF-a	GDCA+stool-18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.656	0.613	no	no	no	no	no	no	DM-LS
Methanobrevibacter	TNF-a	Methanobrevibacter+L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.629	0.613	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	TNF-a	L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.613	no	no	no	no	no	no	DM-LS
CDCA+stool	TNF-a	CDCA+stool-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.663	0.613	no	no	no	no	no	no	DM-LS
CA+stool	TNF-a	CA+stool-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	DM-LS
CA+stool	TNF-a	CA+stool-18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	DM-LS
CA+stool	TNF-a	CA+stool-20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia+Platinum drug resistance+Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia-Neutrophil extracellular trap formation-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia-Cysteine+blood-Eotaxin+IL-4+TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia+Platinum drug resistance+Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia-Neutrophil extracellular trap formation-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia-Cysteine+blood-Eotaxin-GM-CSF-TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia+Primary immunodeficiency+FGF basic+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia+Platinum drug resistance+Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia-Neutrophil extracellular trap formation-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia-Cysteine+blood-Eotaxin+IL-17A+TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia-16:0/22:6-PE+blood-L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia-Cysteine+blood+L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia-Cystine+blood+L-2-Aminobutyric acid+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia-16:0/22:6-PE+blood+18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia+Platinum drug resistance-18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia-cGMP-PKG signaling pathway+18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia-PPAR signaling pathway+18:0/22:6-PE+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia-16:0/22:6-PE+blood-20:1+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
Slackia	TNF-a	Slackia-15-HETE+blood-20:1+blood-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.94	0.613	no	no	no	no	no	no	DM-LS
HDCA+blood	TNF-a	HDCA+blood-Sarcosine+blood-FGF basic+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.483	0.613	no	no	no	no	no	no	DM-LS
UDCA+stool	TNF-a	UDCA+stool-20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.266	0.613	no	no	no	no	no	no	DM-LS
UDCA+stool	TNF-a	UDCA+stool-18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.266	0.613	no	no	no	no	no	no	DM-LS
TDCA+stool	TNF-a	TDCA+stool+UDCA+stool-20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.963	0.613	no	no	no	no	no	no	DM-LS
TDCA+stool	TNF-a	TDCA+stool+UDCA+stool-18:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.963	0.613	no	no	no	no	no	no	DM-LS
nutriCA+stool	TNF-a	nutriCA+stool-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.481	0.613	no	no	no	no	no	no	DM-LS
GDCA+blood	TNF-a	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.632	0.613	no	no	no	no	no	no	DM-LS
GDCA+blood	TNF-a	GDCA+blood+iso-LCA+blood-Sarcosine+blood-FGF basic+IL-17A+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.632	0.613	no	no	no	no	no	no	DM-LS
GDCA+blood	TNF-a	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-4+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.632	0.613	no	no	no	no	no	no	DM-LS
GDCA+blood	TNF-a	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.632	0.613	no	no	no	no	no	no	DM-LS
acetic acid C2+blood	TNF-a	acetic acid C2+blood-L-Alanine+blood-FGF basic+IL-17A+TNF-a	Indirect	serum_scfa	serum_cytokines	0.000193	0.613	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	TNF-a	acetic acid C2+blood-Sarcosine+blood-FGF basic+IL-17A+TNF-a	Indirect	serum_scfa	serum_cytokines	0.000193	0.613	up	dn	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	TNF-a	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-4+TNF-a	Indirect	serum_scfa	serum_cytokines	0.117	0.613	no	no	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	TNF-a	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF-TNF-a	Indirect	serum_scfa	serum_cytokines	0.117	0.613	no	no	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	TNF-a	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-17A+TNF-a	Indirect	serum_scfa	serum_cytokines	0.117	0.613	no	no	no	no	no	no	DM-LS
Adlercreutzia	TNF-a	Adlercreutzia-16:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.548	0.613	no	no	no	no	no	no	DM-LS
Clostridium	TNF-a	Clostridium-20:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	TNF-a	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+IL-1ra-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.48	0.613	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	TNF-a	12-ketoDCA+blood-20:0-LPC+blood+20:1+blood-IL-1ra-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.517	0.613	no	no	no	no	no	no	DM-LS
Butyricicoccus	TNF-a	Butyricicoccus-Phenylacetic acid+stool-IL-1ra-TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	DM-LS
Blautia	MIP-1b	Blautia+14:0/20:4-PC+blood+MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	DM-LS
Parabacteroides	MIP-1b	Parabacteroides-Glucagon signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-LS
Parabacteroides	MIP-1b	Parabacteroides+Apoptosis-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-LS
Parabacteroides	MIP-1b	Parabacteroides-GCA+stool+MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	DM-LS
Dorea	MIP-1b	Dorea-Lipid and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	DM-LS
Faecalibacterium	MIP-1b	Faecalibacterium-Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	DM-LS
TUDCA+blood	MIP-1b	TUDCA+blood+Eotaxin+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.0282	0.632	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	MIP-1b	isocapric acid iso-C6+blood-TMAO+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.0458	0.632	no	no	dn	no	no	no	DM-LS
Bacteroides	MIP-1b	Bacteroides+TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	DM-LS
Bacteroides	MIP-1b	Bacteroides-GCA+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	DM-LS
Propionic acid+stool	MIP-1b	Propionic acid+stool-MUFA%+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.632	dn	no	up	no	no	no	DM-LS
5-Hydroxyindole-3-acetic Acid+urine	MIP-1b	5-Hydroxyindole-3-acetic Acid+urine-IL-9+MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.0405	0.632	no	dn	dn	no	no	no	DM-LS
[Ruminococcus]	MIP-1b	[Ruminococcus]-MUFA%+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0679	0.632	no	no	dn	no	no	no	DM-LS
GUDCA+blood	MIP-1b	GUDCA+blood-LCA+blood+TMAO+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.632	no	no	dn	no	no	no	DM-LS
Acetic acid+stool	MIP-1b	Acetic acid+stool-Cysteine+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.0656	0.632	dn	no	no	no	no	no	DM-LS
Alistipes	MIP-1b	Alistipes-L-Aspartic acid+blood+TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	DM-LS
Alistipes	MIP-1b	Alistipes+12-ketoDCA+blood-IL-9+MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	DM-LS
Alistipes	MIP-1b	Alistipes+12-ketoDCA+blood+GDCA+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	DM-LS
Alistipes	MIP-1b	Alistipes-HIF-1 signaling pathway-Apoptosis-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	DM-LS
Butyricimonas	MIP-1b	Butyricimonas-14:0/20:4-PC+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.17	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-EPA+blood+TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-T cell receptor signaling pathway-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Signaling pathways regulating pluripotency of stem cells-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Spinocerebellar ataxia-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Long-term potentiation-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Insulin resistance-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Prostate cancer-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-NF-kappa B signaling pathway-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Gastric cancer-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-MicroRNAs in cancer-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-PD-L1 expression and PD-1 checkpoint pathway in cancer-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-T cell receptor signaling pathway+Renal cell carcinoma+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Long-term potentiation+Renal cell carcinoma+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Signaling pathways regulating pluripotency of stem cells+Cushing syndrome+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Signaling pathways regulating pluripotency of stem cells+Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Colorectal cancer+Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Glioma+Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Long-term potentiation+Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Choline metabolism in cancer+Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Gastric cancer+Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-ErbB signaling pathway+Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system+Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Signaling pathways regulating pluripotency of stem cells-MUFA%+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Choline metabolism in cancer-MUFA%+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Gastric cancer-MUFA%+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella+Arachidonic acid metabolism+Biosynthesis of amino acids-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Influenza A-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella+Parkinson disease+14:0/16:0-PC+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Wnt signaling pathway-Systemic lupus erythematosus-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Signaling pathways regulating pluripotency of stem cells-Systemic lupus erythematosus-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-Systemic lupus erythematosus-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Spinocerebellar ataxia-Systemic lupus erythematosus-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Choline metabolism in cancer-Systemic lupus erythematosus-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Insulin resistance-Systemic lupus erythematosus-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Gastric cancer-Systemic lupus erythematosus-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Systemic lupus erythematosus-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Wnt signaling pathway-Pertussis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Signaling pathways regulating pluripotency of stem cells-Pertussis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-Pertussis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Spinocerebellar ataxia-Pertussis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Pertussis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation+Adrenergic signaling in cardiomyocytes+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-Apoptosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Apoptosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Wnt signaling pathway-20:2+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Colorectal cancer-20:2+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-20:2+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Glioma-20:2+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Long-term potentiation-20:2+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-ErbB signaling pathway-20:2+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-20:2+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation+Cell cycle+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella+Arachidonic acid metabolism-Cell cycle+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-ErbB signaling pathway+Cell cycle+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system+Cell cycle+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-T cell receptor signaling pathway+9-HODE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Signaling pathways regulating pluripotency of stem cells+9-HODE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-Neuroactive ligand-receptor interaction-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Neuroactive ligand-receptor interaction-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Wnt signaling pathway+CA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system+CA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-Lysosome-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Lysosome-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-Phagosome-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Phagosome-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Wnt signaling pathway-Fc gamma R-mediated phagocytosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Signaling pathways regulating pluripotency of stem cells-Fc gamma R-mediated phagocytosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-Fc gamma R-mediated phagocytosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Fc gamma R-mediated phagocytosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation+Ras signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-ErbB signaling pathway+Ras signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Wnt signaling pathway-IL-17 signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Signaling pathways regulating pluripotency of stem cells-IL-17 signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-IL-17 signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-NF-kappa B signaling pathway+IL-17 signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-IL-17 signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Wnt signaling pathway+Glucagon signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-T cell receptor signaling pathway+Glucagon signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Signaling pathways regulating pluripotency of stem cells+Glucagon signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation+Glucagon signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Long-term potentiation+Glucagon signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system+Glucagon signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Wnt signaling pathway-Leukocyte transendothelial migration-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Signaling pathways regulating pluripotency of stem cells-Leukocyte transendothelial migration-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-Leukocyte transendothelial migration-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Leukocyte transendothelial migration-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-Yersinia infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Yersinia infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Wnt signaling pathway-Lipid and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Signaling pathways regulating pluripotency of stem cells-Lipid and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-Lipid and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Gastric cancer-Lipid and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Lipid and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Wnt signaling pathway-Neutrophil extracellular trap formation-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Signaling pathways regulating pluripotency of stem cells-Neutrophil extracellular trap formation-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-Neutrophil extracellular trap formation-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Neutrophil extracellular trap formation-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-HDCA+stool+HDCA+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Wnt signaling pathway-Tuberculosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Signaling pathways regulating pluripotency of stem cells-Tuberculosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-Tuberculosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Insulin resistance-Tuberculosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella+Parkinson disease-Tuberculosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Tuberculosis-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Wnt signaling pathway-Staphylococcus aureus infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Signaling pathways regulating pluripotency of stem cells-Staphylococcus aureus infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-Staphylococcus aureus infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Spinocerebellar ataxia-Staphylococcus aureus infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Long-term potentiation-Staphylococcus aureus infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Insulin resistance-Staphylococcus aureus infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Staphylococcus aureus infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Wnt signaling pathway-Salmonella infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-Salmonella infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Insulin resistance-Salmonella infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Salmonella infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Long-term potentiation+Dopaminergic synapse+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Wnt signaling pathway-Pathogenic Escherichia coli infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Signaling pathways regulating pluripotency of stem cells-Pathogenic Escherichia coli infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-Pathogenic Escherichia coli infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Spinocerebellar ataxia-Pathogenic Escherichia coli infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Insulin resistance-Pathogenic Escherichia coli infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Pathogenic Escherichia coli infection-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Glioma+GCA+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Long-term potentiation+GCA+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Wnt signaling pathway-Osteoclast differentiation-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-RNA degradation-Osteoclast differentiation-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-NF-kappa B signaling pathway+Osteoclast differentiation-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Phosphatidylinositol signaling system-Osteoclast differentiation-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Long-term potentiation+GCDCA+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella+Arachidonic acid metabolism-mRNA surveillance pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-LCA+stool+GDCA+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1b	Collinsella-Prolactin signaling pathway+GDCA+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	MIP-1b	total_blood_scfa+blood+TUDCA+blood+Eotaxin+MIP-1b	Indirect	serum_scfa	serum_cytokines	0.168	0.632	no	no	no	no	no	no	DM-LS
[Eubacterium]	MIP-1b	[Eubacterium]-Yersinia infection-MIP-1b	Indirect	Genus	serum_cytokines	0.0692	0.632	no	no	no	no	no	no	DM-LS
[Eubacterium]	MIP-1b	[Eubacterium]-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.0692	0.632	no	no	no	no	no	no	DM-LS
[Eubacterium]	MIP-1b	[Eubacterium]-Pathogenic Escherichia coli infection-MIP-1b	Indirect	Genus	serum_cytokines	0.0692	0.632	no	no	no	no	no	no	DM-LS
[Eubacterium]	MIP-1b	[Eubacterium]-Salmonella infection-MIP-1b	Indirect	Genus	serum_cytokines	0.0692	0.632	no	no	no	no	no	no	DM-LS
[Eubacterium]	MIP-1b	[Eubacterium]-Influenza A-MIP-1b	Indirect	Genus	serum_cytokines	0.0692	0.632	no	no	no	no	no	no	DM-LS
[Eubacterium]	MIP-1b	[Eubacterium]-Phagosome-MIP-1b	Indirect	Genus	serum_cytokines	0.0692	0.632	no	no	no	no	no	no	DM-LS
LCA+stool	MIP-1b	LCA+stool+GDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.632	no	no	no	no	no	no	DM-LS
Akkermansia	MIP-1b	Akkermansia-MIP-1b	Direct	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	DM-LS
Bifidobacterium	MIP-1b	Bifidobacterium+d18:1-18:1-SM+blood-GDCA+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.105	0.632	no	dn	no	no	no	no	DM-LS
Bifidobacterium	MIP-1b	Bifidobacterium+Glycine+blood+MUFA%+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.105	0.632	no	dn	no	no	no	no	DM-LS
Bifidobacterium	MIP-1b	Bifidobacterium+Chemical carcinogenesis - receptor activation-MUFA%+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.105	0.632	no	dn	no	no	no	no	DM-LS
Bifidobacterium	MIP-1b	Bifidobacterium+Chemical carcinogenesis - receptor activation+Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.105	0.632	no	dn	no	no	no	no	DM-LS
Ruminococcus	MIP-1b	Ruminococcus+Phagosome-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	DM-LS
GCDCA+blood	MIP-1b	GCDCA+blood+GUDCA+blood-LCA+blood+TMAO+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.632	no	no	no	no	no	no	DM-LS
GCDCA+blood	MIP-1b	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.632	no	no	no	no	no	no	DM-LS
Succinivibrio	MIP-1b	Succinivibrio-Phospholipase D signaling pathway+Cushing syndrome+MIP-1b	Indirect	Genus	serum_cytokines	0.138	0.632	no	no	no	no	no	no	DM-LS
Succinivibrio	MIP-1b	Succinivibrio-Phospholipase D signaling pathway-MUFA%+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.138	0.632	no	no	no	no	no	no	DM-LS
Succinivibrio	MIP-1b	Succinivibrio-Phospholipase D signaling pathway+Osteoclast differentiation-MIP-1b	Indirect	Genus	serum_cytokines	0.138	0.632	no	no	no	no	no	no	DM-LS
Succinivibrio	MIP-1b	Succinivibrio-L-Tyrosine+stool+TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.138	0.632	no	no	no	no	no	no	DM-LS
Succinivibrio	MIP-1b	Succinivibrio-L-Phenylalanine+stool+TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.138	0.632	no	no	no	no	no	no	DM-LS
Succinivibrio	MIP-1b	Succinivibrio-L-Phenylalanine+stool+Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.138	0.632	no	no	no	no	no	no	DM-LS
ACA+blood	MIP-1b	ACA+blood-Eotaxin+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.338	0.632	no	no	no	no	no	no	DM-LS
DCA+stool	MIP-1b	DCA+stool+GDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.632	no	no	no	no	no	no	DM-LS
DCA+stool	MIP-1b	DCA+stool-GCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.632	no	no	no	no	no	no	DM-LS
DCA+stool	MIP-1b	DCA+stool-IL-9+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.632	no	no	no	no	no	no	DM-LS
DCA+stool	MIP-1b	DCA+stool-GDCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.632	no	no	no	no	no	no	DM-LS
2-hydroxyhippuric acid+urine	MIP-1b	2-hydroxyhippuric acid+urine+5-Hydroxyindole-3-acetic Acid+urine-IL-9+MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.215	0.632	no	no	no	no	no	no	DM-LS
Butyric acid+stool	MIP-1b	Butyric acid+stool-12-ketoDCA+blood-IL-9+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.632	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	MIP-1b	Butyric acid+stool+Propionic acid+stool-MUFA%+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.632	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	MIP-1b	Butyric acid+stool-12-ketoDCA+blood+GDCA+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.632	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	MIP-1b	Butyric acid+stool-Phenylacetic acid+stool+Cysteine+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.632	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	MIP-1b	Butyric acid+stool-Phenylacetic acid+stool+HDCA+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.632	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	MIP-1b	Butyric acid+stool-Phenylacetic acid+stool+TMAO+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.632	dn	no	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	MIP-1b	4-hydroxybenzoic acid+stool-TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.632	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	MIP-1b	4-hydroxybenzoic acid+stool-HDCA+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.632	no	dn	no	no	no	no	DM-LS
GCA+blood	MIP-1b	GCA+blood+GDCA+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.16	0.632	no	no	no	no	no	no	DM-LS
ACA+stool	MIP-1b	ACA+stool-GCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.417	0.632	no	no	no	no	no	no	DM-LS
ACA+stool	MIP-1b	ACA+stool+20:2+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.417	0.632	no	no	no	no	no	no	DM-LS
CDCA+blood	MIP-1b	CDCA+blood-MUFA%+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.632	no	no	no	no	no	no	DM-LS
CDCA+blood	MIP-1b	CDCA+blood-Cysteine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.632	no	no	no	no	no	no	DM-LS
capric acid C6+blood	MIP-1b	capric acid C6+blood+MUFA%+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.433	0.632	no	no	no	no	no	no	DM-LS
Pyramidobacter	MIP-1b	Pyramidobacter-Carbon metabolism-MIP-1b	Indirect	Genus	serum_cytokines	0.45	0.632	no	no	no	no	no	no	DM-LS
Pyramidobacter	MIP-1b	Pyramidobacter-Lysosome-MIP-1b	Indirect	Genus	serum_cytokines	0.45	0.632	no	no	no	no	no	no	DM-LS
Pyramidobacter	MIP-1b	Pyramidobacter+Glucagon signaling pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.45	0.632	no	no	no	no	no	no	DM-LS
Prevotella	MIP-1b	Prevotella+Aldosterone synthesis and secretion+MIP-1b	Indirect	Genus	serum_cytokines	0.287	0.632	no	no	no	no	no	no	DM-LS
Prevotella	MIP-1b	Prevotella+Adrenergic signaling in cardiomyocytes+MIP-1b	Indirect	Genus	serum_cytokines	0.287	0.632	no	no	no	no	no	no	DM-LS
Prevotella	MIP-1b	Prevotella+Inflammatory mediator regulation of TRP channels+MIP-1b	Indirect	Genus	serum_cytokines	0.287	0.632	no	no	no	no	no	no	DM-LS
Prevotella	MIP-1b	Prevotella-Carbon metabolism-MIP-1b	Indirect	Genus	serum_cytokines	0.287	0.632	no	no	no	no	no	no	DM-LS
Prevotella	MIP-1b	Prevotella+Amphetamine addiction+MIP-1b	Indirect	Genus	serum_cytokines	0.287	0.632	no	no	no	no	no	no	DM-LS
Prevotella	MIP-1b	Prevotella+Dopaminergic synapse+MIP-1b	Indirect	Genus	serum_cytokines	0.287	0.632	no	no	no	no	no	no	DM-LS
Prevotella	MIP-1b	Prevotella+Cushing syndrome+MIP-1b	Indirect	Genus	serum_cytokines	0.287	0.632	no	no	no	no	no	no	DM-LS
TCA+blood	MIP-1b	TCA+blood+TUDCA+blood+Eotaxin+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.339	0.632	no	no	no	no	no	no	DM-LS
iso-DCA+blood	MIP-1b	iso-DCA+blood+L-Lysine+blood+Taurine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.38	0.632	no	no	no	no	no	no	DM-LS
iso-DCA+blood	MIP-1b	iso-DCA+blood+L-Phenylalanine+blood+Taurine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.38	0.632	no	no	no	no	no	no	DM-LS
HCA+stool	MIP-1b	HCA+stool-Cysteine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.632	no	no	no	no	no	no	DM-LS
Roseburia	MIP-1b	Roseburia-20:2+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.495	0.632	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool+DCA+stool-GDCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool+HDCA+stool+HDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool+DCA+stool+GDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool+LCA+stool+GDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool+DCA+stool-GCA+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool+DCA+stool-IL-9+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool-Glycine+blood+MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool+20:4/18:0-PE+blood-TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	DM-LS
4-Hydroxyphenylacetic acid+urine	MIP-1b	4-Hydroxyphenylacetic acid+urine-5-Hydroxyindole-3-acetic Acid+urine-IL-9+MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.0321	0.632	up	up	no	no	no	no	DM-LS
GLCA+blood	MIP-1b	GLCA+blood+HDCA+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.319	0.632	no	no	no	no	no	no	DM-LS
GLCA+blood	MIP-1b	GLCA+blood-IL-9+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.319	0.632	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	MIP-1b	L-Tryptophan+stool+TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.632	no	no	no	no	no	no	DM-LS
CA+blood	MIP-1b	CA+blood+MIP-1b	Direct	serum_bileacids	serum_cytokines	0.606	0.632	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	MIP-1b	L-Phenylalanine+stool+TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.632	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	MIP-1b	L-Phenylalanine+stool+Cysteine+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.632	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	MIP-1b	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.407	0.632	no	no	no	no	no	no	DM-LS
GCA+stool	MIP-1b	GCA+stool+MIP-1b	Direct	stool_bileacids	serum_cytokines	0.0809	0.632	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	MIP-1b	T-a-MCA+blood+UFA%+blood-Eotaxin+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.478	0.632	no	no	no	no	no	no	DM-LS
Coprococcus	MIP-1b	Coprococcus-GCDCA+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.612	0.632	no	no	no	no	no	no	DM-LS
Coprococcus	MIP-1b	Coprococcus-16:0/18:3-PC+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.612	0.632	no	no	no	no	no	no	DM-LS
Coprococcus	MIP-1b	Coprococcus-Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.612	0.632	no	no	no	no	no	no	DM-LS
Coprococcus	MIP-1b	Coprococcus-Amphetamine addiction+MIP-1b	Indirect	Genus	serum_cytokines	0.612	0.632	no	no	no	no	no	no	DM-LS
Coprococcus	MIP-1b	Coprococcus-Aldosterone synthesis and secretion+MIP-1b	Indirect	Genus	serum_cytokines	0.612	0.632	no	no	no	no	no	no	DM-LS
Coprococcus	MIP-1b	Coprococcus-CA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.612	0.632	no	no	no	no	no	no	DM-LS
Coprococcus	MIP-1b	Coprococcus-Dopaminergic synapse+MIP-1b	Indirect	Genus	serum_cytokines	0.612	0.632	no	no	no	no	no	no	DM-LS
Coprococcus	MIP-1b	Coprococcus+Biosynthesis of amino acids-MIP-1b	Indirect	Genus	serum_cytokines	0.612	0.632	no	no	no	no	no	no	DM-LS
Coprococcus	MIP-1b	Coprococcus+Salmonella infection-MIP-1b	Indirect	Genus	serum_cytokines	0.612	0.632	no	no	no	no	no	no	DM-LS
Oscillospira	MIP-1b	Oscillospira-Adrenergic signaling in cardiomyocytes+MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	DM-LS
HCA+blood	MIP-1b	HCA+blood-MUFA+blood+MUFA%+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.544	0.632	no	no	no	no	no	no	DM-LS
iso-LCA+stool	MIP-1b	iso-LCA+stool+LCA+stool+GDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.632	no	no	no	no	no	no	DM-LS
iso-LCA+stool	MIP-1b	iso-LCA+stool-CDCA+blood-Cysteine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.632	no	no	no	no	no	no	DM-LS
iso-LCA+stool	MIP-1b	iso-LCA+stool+Phenylacetic acid+stool+Cysteine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.632	no	no	no	no	no	no	DM-LS
iso-LCA+stool	MIP-1b	iso-LCA+stool+Phenylacetic acid+stool+HDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.632	no	no	no	no	no	no	DM-LS
iso-LCA+stool	MIP-1b	iso-LCA+stool-nutriCA+stool+CA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.632	no	no	no	no	no	no	DM-LS
iso-LCA+stool	MIP-1b	iso-LCA+stool-CDCA+blood-MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.632	no	no	no	no	no	no	DM-LS
iso-LCA+stool	MIP-1b	iso-LCA+stool-Glycine+blood+MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.632	no	no	no	no	no	no	DM-LS
iso-LCA+stool	MIP-1b	iso-LCA+stool+iso-LCA+blood+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.632	no	no	no	no	no	no	DM-LS
iso-LCA+stool	MIP-1b	iso-LCA+stool+LCA+blood+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.632	no	no	no	no	no	no	DM-LS
iso-LCA+stool	MIP-1b	iso-LCA+stool+Phenylacetic acid+stool+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.632	no	no	no	no	no	no	DM-LS
iso-LCA+stool	MIP-1b	iso-LCA+stool-18:1-LPE+blood-TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.632	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	MIP-1b	2-methyl-butyric acid m-C4+blood-CA+blood+MIP-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.632	no	no	no	no	no	no	DM-LS
DCA+blood	MIP-1b	DCA+blood-MUFA%+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.632	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-LCA+blood+TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-iso-LCA+blood+TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+Cysteine+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood-MUFA%+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2n6c+blood+20:2+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	DM-LS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	MIP-1b	"3-(3,4-dihydroxyphenyl)propionic acid+urine-5-Hydroxyindole-3-acetic Acid+urine-IL-9+MIP-1b"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.632	up	up	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	MIP-1b	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.632	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	MIP-1b	Indole-3-Acetic acid+stool+L-Tryptophan+stool+TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.632	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	MIP-1b	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.632	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	MIP-1b	Indole-3-Acetic acid+stool+L-Tyrosine+stool+TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.632	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	MIP-1b	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+Cysteine+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.632	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	MIP-1b	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+Cysteine+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.632	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	MIP-1b	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+HDCA+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.632	no	no	no	no	no	no	DM-LS
TCA+stool	MIP-1b	TCA+stool+16:0/18:1-PC+blood+Cysteine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-LS
TCA+stool	MIP-1b	TCA+stool+18:0/16:0-PC+blood+Cysteine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-LS
TCA+stool	MIP-1b	TCA+stool+16:0/18:1-PC+blood-HDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-LS
TCA+stool	MIP-1b	TCA+stool+18:0/16:0-PC+blood-HDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-LS
TCA+stool	MIP-1b	TCA+stool+18:1/18:1-PC+blood-HDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-LS
TCA+stool	MIP-1b	TCA+stool+16:0/20:3-PC+blood-HDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-LS
TCA+stool	MIP-1b	TCA+stool+16:0/18:1-PC+blood+MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-LS
TCA+stool	MIP-1b	TCA+stool+18:0/16:0-PC+blood+MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-LS
TCA+stool	MIP-1b	TCA+stool-16:0/20:5-PC+blood-MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-LS
TCA+stool	MIP-1b	TCA+stool-16:0/20:5-PC+blood-20:2+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-LS
TCA+stool	MIP-1b	TCA+stool+18:1/18:1-PC+blood+20:2+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-LS
TCA+stool	MIP-1b	TCA+stool+16:0/20:3-PC+blood+20:2+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-LS
TCA+stool	MIP-1b	TCA+stool+18:0/18:1-PC+blood+20:2+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-LS
TCA+stool	MIP-1b	TCA+stool-16:0/20:5-PC+blood+CA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-LS
TCA+stool	MIP-1b	TCA+stool+18:0/18:0-PC+blood+IL-9+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-LS
TCA+stool	MIP-1b	TCA+stool+18:0/18:1-PC+blood+IL-9+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1b	HDCA+stool+HDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira+18:1/20:3-PC+blood-CA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira+16:0/18:2-PC+blood+Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira+18:0/18:2-PC+blood+Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira+18:1/16:0-PC+blood+Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira-d18:1-16:1-SM+blood-MUFA%+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira-d18:1-14:0-SM+blood-MUFA%+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira+16:0/18:2-PC+blood+MUFA%+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira+18:1/16:0-PC+blood+MUFA%+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira-Adherens junction+Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira+Choline+blood-Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira-Adherens junction+HDCA+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira+18:1/18:1-PC+blood-HDCA+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira+18:1/20:3-PC+blood-HDCA+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira+16:0/20:3-PC+blood-HDCA+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira-Adherens junction+Influenza A-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira-Adherens junction+Leukocyte transendothelial migration-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira-Adherens junction+Pathogenic Escherichia coli infection-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira-Adherens junction+Salmonella infection-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira-Adherens junction-Renal cell carcinoma+MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira-Adherens junction+Yersinia infection-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira+18:1/18:1-PC+blood+20:2+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira+18:1/20:3-PC+blood+20:2+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira+16:0/20:3-PC+blood+20:2+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1b	Lachnospira-Adherens junction-9-HODE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	DM-LS
Fusobacterium	MIP-1b	Fusobacterium+MUFA%+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.628	0.632	no	no	no	no	no	no	DM-LS
isobutyric acid C4+blood	MIP-1b	isobutyric acid C4+blood+MUFA%+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.0151	0.632	up	up	no	no	no	no	DM-LS
GCDCA+stool	MIP-1b	GCDCA+stool+MIP-1b	Direct	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1b	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+Cysteine+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.632	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1b	5-Hydroxytryptamine+stool-Acetic acid+stool-Cysteine+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.632	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1b	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.632	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1b	5-Hydroxytryptamine+stool+L-Tyrosine+stool+TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.632	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1b	5-Hydroxytryptamine+stool-Propionic acid+stool-MUFA%+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.632	dn	dn	no	no	no	no	DM-LS
Odoribacter	MIP-1b	Odoribacter+IL-8-MIP-1b	Indirect	Genus	serum_cytokines	0.798	0.632	no	no	no	no	no	no	DM-LS
Odoribacter	MIP-1b	Odoribacter-14:0/16:0-PC+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.798	0.632	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	MIP-1b	Isobutyric acid+stool+Phenylacetic acid+stool+HDCA+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.632	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	MIP-1b	Isobutyric acid+stool+Phenylacetic acid+stool+Cysteine+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.632	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	MIP-1b	Isobutyric acid+stool+L-Phenylalanine+stool+Cysteine+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.632	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	MIP-1b	Isobutyric acid+stool-nutriCA+stool+CA+blood+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.632	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	MIP-1b	Isobutyric acid+stool+L-Tyrosine+stool+TMAO+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.632	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	MIP-1b	Isobutyric acid+stool+L-Tryptophan+stool+TMAO+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.632	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	MIP-1b	Isobutyric acid+stool+Phenylacetic acid+stool+TMAO+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.632	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	MIP-1b	Isobutyric acid+stool+L-Phenylalanine+stool+TMAO+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.632	no	no	no	no	no	no	DM-LS
2-hydroxyphenylacetic acid+urine	MIP-1b	2-hydroxyphenylacetic acid+urine+4-Hydroxyphenylacetic acid+urine-5-Hydroxyindole-3-acetic Acid+urine-IL-9+MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.763	0.632	no	no	no	no	no	no	DM-LS
Lachnobacterium	MIP-1b	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.867	0.632	no	no	no	no	no	no	DM-LS
Kynurenic acid+stool	MIP-1b	Kynurenic acid+stool+L-Tyrosine+stool+TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.632	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	MIP-1b	Kynurenic acid+stool-nutriCA+stool+CA+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.632	dn	dn	no	no	no	no	DM-LS
Anaerostipes	MIP-1b	Anaerostipes-EPA+blood+TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	DM-LS
Anaerostipes	MIP-1b	Anaerostipes-Non-small cell lung cancer-Systemic lupus erythematosus-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	DM-LS
Anaerostipes	MIP-1b	Anaerostipes-Insulin resistance-Systemic lupus erythematosus-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	DM-LS
Anaerostipes	MIP-1b	Anaerostipes-Insulin resistance-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	DM-LS
Anaerostipes	MIP-1b	Anaerostipes-Prostate cancer-Fluid shear stress and atherosclerosis-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	DM-LS
Anaerostipes	MIP-1b	Anaerostipes-Non-small cell lung cancer+Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	DM-LS
Anaerostipes	MIP-1b	Anaerostipes+TUDCA+blood+Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	DM-LS
Anaerostipes	MIP-1b	Anaerostipes-Insulin resistance-Staphylococcus aureus infection-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	DM-LS
Anaerostipes	MIP-1b	Anaerostipes-Insulin resistance-Pathogenic Escherichia coli infection-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	DM-LS
Anaerostipes	MIP-1b	Anaerostipes-L-Isoleucine+blood+Taurine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	DM-LS
Anaerostipes	MIP-1b	Anaerostipes-Insulin resistance-Salmonella infection-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	DM-LS
Anaerostipes	MIP-1b	Anaerostipes-Insulin resistance-Tuberculosis-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	DM-LS
TUDCA+stool	MIP-1b	TUDCA+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-LS
TUDCA+stool	MIP-1b	TUDCA+stool-UDCA+stool-18:2n6c+blood+20:2+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-LS
TUDCA+stool	MIP-1b	TUDCA+stool-UDCA+stool-16:0/22:6-PC+blood+MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-LS
TUDCA+stool	MIP-1b	TUDCA+stool-UDCA+stool-16:0/18:2-PC+blood+MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-LS
TUDCA+stool	MIP-1b	TUDCA+stool-UDCA+stool+d18:1-16:1-SM+blood-MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-LS
TUDCA+stool	MIP-1b	TUDCA+stool-UDCA+stool+CDCA+blood-MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-LS
TUDCA+stool	MIP-1b	TUDCA+stool-UDCA+stool-20:5/18:0-PC+blood+MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-LS
TUDCA+stool	MIP-1b	TUDCA+stool-UDCA+stool-16:0/18:2-PC+blood+Cysteine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-LS
TUDCA+stool	MIP-1b	TUDCA+stool-UDCA+stool+CDCA+blood-Cysteine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-LS
TUDCA+stool	MIP-1b	TUDCA+stool-UDCA+stool-L-Ornithine+blood+Taurine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-LS
TUDCA+stool	MIP-1b	TUDCA+stool-UDCA+stool-L-Ornithine+blood+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-LS
TUDCA+stool	MIP-1b	TUDCA+stool-UDCA+stool-iso-LCA+blood+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-LS
TUDCA+stool	MIP-1b	TUDCA+stool-UDCA+stool-LCA+blood+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-LS
TUDCA+stool	MIP-1b	TUDCA+stool-UDCA+stool+18:1-LPE+blood-TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.632	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	MIP-1b	Isovaleric acid+stool+L-Phenylalanine+stool+Cysteine+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.632	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	MIP-1b	Isovaleric acid+stool+Phenylacetic acid+stool+Cysteine+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.632	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	MIP-1b	Isovaleric acid+stool+Phenylacetic acid+stool+HDCA+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.632	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	MIP-1b	Isovaleric acid+stool-nutriCA+stool+CA+blood+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.632	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	MIP-1b	Isovaleric acid+stool+L-Phenylalanine+stool+TMAO+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.632	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	MIP-1b	Isovaleric acid+stool+Phenylacetic acid+stool+TMAO+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.632	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	MIP-1b	Isovaleric acid+stool+L-Tyrosine+stool+TMAO+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.632	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	MIP-1b	Isovaleric acid+stool+L-Tryptophan+stool+TMAO+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.632	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1b	Paraprevotella+Arachidonic acid metabolism+Biosynthesis of amino acids-MIP-1b	Indirect	Genus	serum_cytokines	0.118	0.632	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1b	Paraprevotella+Glutathione metabolism-mRNA surveillance pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.118	0.632	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1b	Paraprevotella+Arachidonic acid metabolism-mRNA surveillance pathway+MIP-1b	Indirect	Genus	serum_cytokines	0.118	0.632	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1b	Paraprevotella+18:0/20:2-PC+blood+20:2+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.118	0.632	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1b	Paraprevotella+Arachidonic acid metabolism-Cell cycle+MIP-1b	Indirect	Genus	serum_cytokines	0.118	0.632	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1b	Paraprevotella+Betaine+blood-CA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.118	0.632	no	no	no	no	no	no	DM-LS
iso-LCA+blood	MIP-1b	iso-LCA+blood+TMAO+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.507	0.632	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool+Cysteine+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool+HDCA+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool+TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	DM-LS
Gemmiger	MIP-1b	Gemmiger+TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.595	0.632	no	no	no	no	no	no	DM-LS
Gemmiger	MIP-1b	Gemmiger-GCA+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.595	0.632	no	no	no	no	no	no	DM-LS
GDCA+stool	MIP-1b	GDCA+stool+MIP-1b	Direct	stool_bileacids	serum_cytokines	0.656	0.632	no	no	no	no	no	no	DM-LS
Methanobrevibacter	MIP-1b	Methanobrevibacter+18:2n6c+blood+20:2+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.629	0.632	no	no	no	no	no	no	DM-LS
Methanobrevibacter	MIP-1b	Methanobrevibacter+L-Phenylalanine+stool+Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.629	0.632	no	no	no	no	no	no	DM-LS
Methanobrevibacter	MIP-1b	Methanobrevibacter+L-Tyrosine+stool+TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.629	0.632	no	no	no	no	no	no	DM-LS
Methanobrevibacter	MIP-1b	Methanobrevibacter+L-Phenylalanine+stool+TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.629	0.632	no	no	no	no	no	no	DM-LS
Methanobrevibacter	MIP-1b	Methanobrevibacter+n3+blood+TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.629	0.632	no	no	no	no	no	no	DM-LS
Methanobrevibacter	MIP-1b	Methanobrevibacter+n3+blood-Eotaxin+MIP-1b	Indirect	Genus	serum_cytokines	0.629	0.632	no	no	no	no	no	no	DM-LS
Methanobrevibacter	MIP-1b	Methanobrevibacter+n3+blood+Taurine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.629	0.632	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	MIP-1b	L-Tyrosine+stool+TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool-20:5/18:0-PC+blood-Eotaxin+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool+nutriCA+stool+CA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool-L-Phenylalanine+stool+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool-L-Ornithine+blood+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool-L-Tryptophan+stool+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool+18:1-LPE+blood-TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool-LCA+blood+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool-L-Tyrosine+stool+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool-iso-LCA+blood+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool-Phenylacetic acid+stool+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool-16:0/22:6-PC+blood+MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool-20:5/18:0-PC+blood+MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool+18:2-LPE+blood+9-HODE+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool-L-Ornithine+blood+Taurine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool-L-Lysine+blood+Taurine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool-L-Phenylalanine+stool+Cysteine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool-Phenylacetic acid+stool+Cysteine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool-LCA+stool+GDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool-HDCA+stool+HDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1b	CDCA+stool-Phenylacetic acid+stool+HDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	DM-LS
CA+stool	MIP-1b	CA+stool+CA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	DM-LS
Slackia	MIP-1b	Slackia-Neutrophil extracellular trap formation-MIP-1b	Indirect	Genus	serum_cytokines	0.94	0.632	no	no	no	no	no	no	DM-LS
Slackia	MIP-1b	Slackia-Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.94	0.632	no	no	no	no	no	no	DM-LS
HDCA+blood	MIP-1b	HDCA+blood-MIP-1b	Direct	serum_bileacids	serum_cytokines	0.483	0.632	no	no	no	no	no	no	DM-LS
UDCA+stool	MIP-1b	UDCA+stool-20:5/18:0-PC+blood-Eotaxin+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.632	no	no	no	no	no	no	DM-LS
UDCA+stool	MIP-1b	UDCA+stool-18:2n6c+blood+20:2+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.632	no	no	no	no	no	no	DM-LS
UDCA+stool	MIP-1b	UDCA+stool-16:0/22:6-PC+blood+MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.632	no	no	no	no	no	no	DM-LS
UDCA+stool	MIP-1b	UDCA+stool-16:0/18:2-PC+blood+MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.632	no	no	no	no	no	no	DM-LS
UDCA+stool	MIP-1b	UDCA+stool+d18:1-16:1-SM+blood-MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.632	no	no	no	no	no	no	DM-LS
UDCA+stool	MIP-1b	UDCA+stool+CDCA+blood-MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.632	no	no	no	no	no	no	DM-LS
UDCA+stool	MIP-1b	UDCA+stool-20:5/18:0-PC+blood+MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.632	no	no	no	no	no	no	DM-LS
UDCA+stool	MIP-1b	UDCA+stool-16:0/18:2-PC+blood+Cysteine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.632	no	no	no	no	no	no	DM-LS
UDCA+stool	MIP-1b	UDCA+stool+CDCA+blood-Cysteine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.632	no	no	no	no	no	no	DM-LS
UDCA+stool	MIP-1b	UDCA+stool-L-Ornithine+blood+Taurine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.632	no	no	no	no	no	no	DM-LS
UDCA+stool	MIP-1b	UDCA+stool-L-Ornithine+blood+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.632	no	no	no	no	no	no	DM-LS
UDCA+stool	MIP-1b	UDCA+stool-iso-LCA+blood+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.632	no	no	no	no	no	no	DM-LS
UDCA+stool	MIP-1b	UDCA+stool-LCA+blood+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.632	no	no	no	no	no	no	DM-LS
UDCA+stool	MIP-1b	UDCA+stool+18:1-LPE+blood-TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.632	no	no	no	no	no	no	DM-LS
TDCA+stool	MIP-1b	TDCA+stool+UDCA+stool-20:5/18:0-PC+blood-Eotaxin+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.632	no	no	no	no	no	no	DM-LS
TDCA+stool	MIP-1b	TDCA+stool+UDCA+stool-18:2n6c+blood+20:2+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.632	no	no	no	no	no	no	DM-LS
TDCA+stool	MIP-1b	TDCA+stool+UDCA+stool-16:0/22:6-PC+blood+MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.632	no	no	no	no	no	no	DM-LS
TDCA+stool	MIP-1b	TDCA+stool+UDCA+stool-16:0/18:2-PC+blood+MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.632	no	no	no	no	no	no	DM-LS
TDCA+stool	MIP-1b	TDCA+stool+UDCA+stool+d18:1-16:1-SM+blood-MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.632	no	no	no	no	no	no	DM-LS
TDCA+stool	MIP-1b	TDCA+stool+UDCA+stool+CDCA+blood-MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.632	no	no	no	no	no	no	DM-LS
TDCA+stool	MIP-1b	TDCA+stool+UDCA+stool-20:5/18:0-PC+blood+MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.632	no	no	no	no	no	no	DM-LS
TDCA+stool	MIP-1b	TDCA+stool+UDCA+stool-16:0/18:2-PC+blood+Cysteine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.632	no	no	no	no	no	no	DM-LS
TDCA+stool	MIP-1b	TDCA+stool+UDCA+stool+CDCA+blood-Cysteine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.632	no	no	no	no	no	no	DM-LS
TDCA+stool	MIP-1b	TDCA+stool+UDCA+stool-L-Ornithine+blood+Taurine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.632	no	no	no	no	no	no	DM-LS
TDCA+stool	MIP-1b	TDCA+stool+UDCA+stool-L-Ornithine+blood+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.632	no	no	no	no	no	no	DM-LS
TDCA+stool	MIP-1b	TDCA+stool+UDCA+stool-iso-LCA+blood+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.632	no	no	no	no	no	no	DM-LS
TDCA+stool	MIP-1b	TDCA+stool+UDCA+stool-LCA+blood+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.632	no	no	no	no	no	no	DM-LS
TDCA+stool	MIP-1b	TDCA+stool+UDCA+stool+18:1-LPE+blood-TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.632	no	no	no	no	no	no	DM-LS
LCA+blood	MIP-1b	LCA+blood+TMAO+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.884	0.632	no	no	no	no	no	no	DM-LS
nutriCA+stool	MIP-1b	nutriCA+stool+CA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.632	no	no	no	no	no	no	DM-LS
GDCA+blood	MIP-1b	GDCA+blood-MIP-1b	Direct	serum_bileacids	serum_cytokines	0.632	0.632	no	no	no	no	no	no	DM-LS
acetic acid C2+blood	MIP-1b	acetic acid C2+blood+capric acid C6+blood+MUFA%+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.632	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	MIP-1b	acetic acid C2+blood-d18:1-14:1-SM+blood-MUFA%+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.632	up	dn	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	MIP-1b	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+MIP-1b	Indirect	serum_scfa	serum_cytokines	0.117	0.632	no	no	no	no	no	no	DM-LS
Adlercreutzia	MIP-1b	Adlercreutzia-14:0+blood+14:0/20:4-PC+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.548	0.632	no	no	no	no	no	no	DM-LS
Adlercreutzia	MIP-1b	Adlercreutzia-14:0+blood+14:0/16:0-PC+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.548	0.632	no	no	no	no	no	no	DM-LS
Adlercreutzia	MIP-1b	Adlercreutzia-16:0/20:5-PC+blood-20:2+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.548	0.632	no	no	no	no	no	no	DM-LS
Adlercreutzia	MIP-1b	Adlercreutzia+18:1-LPC+blood+20:2+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.548	0.632	no	no	no	no	no	no	DM-LS
Adlercreutzia	MIP-1b	Adlercreutzia-16:0/20:5-PC+blood+CA+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.548	0.632	no	no	no	no	no	no	DM-LS
Adlercreutzia	MIP-1b	Adlercreutzia-16:0/20:5-PC+blood-MUFA%+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.548	0.632	no	no	no	no	no	no	DM-LS
Adlercreutzia	MIP-1b	Adlercreutzia-14:0+blood+16:0/18:3-PC+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.548	0.632	no	no	no	no	no	no	DM-LS
Adlercreutzia	MIP-1b	Adlercreutzia-EPA+blood+TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.548	0.632	no	no	no	no	no	no	DM-LS
Adlercreutzia	MIP-1b	Adlercreutzia-14:0+blood+16:0/16:1-PC+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.548	0.632	no	no	no	no	no	no	DM-LS
Clostridium	MIP-1b	Clostridium-14:0/16:0-PC+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.925	0.632	no	no	no	no	no	no	DM-LS
Clostridium	MIP-1b	Clostridium-14:0/20:4-PC+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.925	0.632	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+Cysteine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+Cysteine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood-HDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood-HDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood-HDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood-HDCA+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood-MUFA%+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood-20:2+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+20:2+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+20:2+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-TCA+stool+18:0/18:1-PC+blood+20:2+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+CA+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-TCA+stool+18:0/18:0-PC+blood+IL-9+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-TCA+stool+18:0/18:1-PC+blood+IL-9+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	MIP-1b	12-ketoDCA+blood-IL-9+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.632	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	MIP-1b	12-ketoDCA+blood+GDCA+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.632	no	no	no	no	no	no	DM-LS
Butyricicoccus	MIP-1b	Butyricicoccus+Phagosome-MIP-1b	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	DM-LS
Blautia	IL-9	Blautia+GCA+blood+GDCA+blood-IL-9	Indirect	Genus	serum_cytokines	1.36E-05	0.906	up	dn	dn	no	no	no	DM-LS
Blautia	IL-9	Blautia+14:0/20:4-PC+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	1.36E-05	0.906	up	dn	dn	no	no	no	DM-LS
Blautia	IL-9	Blautia-12-ketoDCA+stool+DCA+stool-IL-9	Indirect	Genus	serum_cytokines	1.36E-05	0.906	up	dn	dn	no	no	no	DM-LS
Blautia	IL-9	Blautia+14:0/20:4-PC+blood+16:0/18:3-PC+blood+IL-9	Indirect	Genus	serum_cytokines	1.36E-05	0.906	up	dn	dn	no	no	no	DM-LS
Blautia	IL-9	Blautia+14:0/20:4-PC+blood-GLCA+blood-IL-9	Indirect	Genus	serum_cytokines	1.36E-05	0.906	up	dn	dn	no	no	no	DM-LS
Parabacteroides	IL-9	Parabacteroides-GCA+stool+IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	DM-LS
Dorea	IL-9	Dorea-Lipid and atherosclerosis-14:0/20:4-PC+blood-GLCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	Dorea-18:0/22:6-PE+blood+18:1/20:4-PE+blood+GLCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	Dorea-Lipid and atherosclerosis-14:0/18:2-PC+blood-GLCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	"Dorea+d18:1-20:0-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-5-Hydroxyindole-3-acetic Acid+urine-IL-9"	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	Dorea-Lipid and atherosclerosis-14:0/20:4-PC+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	Dorea-Lipid and atherosclerosis+MUFA%+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	Dorea-18:0/22:6-PE+blood+20:2/18:1-PE+blood-HDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	Dorea-18:0/22:6-PE+blood+18:3/16:0-PE+blood-HDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	Dorea-Lipid and atherosclerosis-14:0/20:4-PC+blood+16:0/18:3-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	Dorea-Lipid and atherosclerosis-14:0/18:2-PC+blood+16:0/18:3-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	Dorea-18:0/22:6-PE+blood+20:2/18:1-PE+blood-L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	Dorea-18:0/22:6-PE+blood+18:1/18:0-PE+blood-L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	Dorea-18:0/22:6-PE+blood+20:2/18:3-PE+blood-L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	Dorea-18:0/22:6-PE+blood+18:1/18:2-PE+blood-L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	Dorea-18:0/22:6-PE+blood-L-2-Aminobutyric acid+blood+L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	Dorea-18:0/22:6-PE+blood+18:1/18:1-PE+blood-L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	Dorea-Lipid and atherosclerosis+18:1/18:1-PE+blood-L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	Dorea-Lipid and atherosclerosis+16:0/22:6-PE+blood-L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Dorea	IL-9	Dorea-18:0/22:6-PE+blood+IL-1ra+IL-8-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	DM-LS
Faecalibacterium	IL-9	Faecalibacterium-Phenylacetic acid+stool+HDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.0039	0.906	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	IL-9	Faecalibacterium-16:0/18:1-PC+blood-HDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.0039	0.906	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	IL-9	Faecalibacterium-16:0/18:1-PC+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.0039	0.906	no	dn	dn	no	no	no	DM-LS
TUDCA+blood	IL-9	TUDCA+blood+Eotaxin+IL-4-IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.0282	0.906	no	no	dn	no	no	no	DM-LS
TUDCA+blood	IL-9	TUDCA+blood+Eotaxin-GM-CSF+IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.0282	0.906	no	no	dn	no	no	no	DM-LS
TUDCA+blood	IL-9	TUDCA+blood+Eotaxin+IL-17A-IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.0282	0.906	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	IL-9	isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF+IL-8-IL-9	Indirect	serum_scfa	serum_cytokines	0.0458	0.906	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	IL-9	isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-4-IL-8-IL-9	Indirect	serum_scfa	serum_cytokines	0.0458	0.906	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	IL-9	isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-17A-IL-8-IL-9	Indirect	serum_scfa	serum_cytokines	0.0458	0.906	no	no	dn	no	no	no	DM-LS
Bacteroides	IL-9	Bacteroides-GCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	DM-LS
Propionic acid+stool	IL-9	Propionic acid+stool-18:0/18:0-PC+blood+IL-9	Indirect	stool_scfa	serum_cytokines	0.0436	0.906	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IL-9	Propionic acid+stool-18:0/18:1-PC+blood+IL-9	Indirect	stool_scfa	serum_cytokines	0.0436	0.906	dn	no	up	no	no	no	DM-LS
5-Hydroxyindole-3-acetic Acid+urine	IL-9	5-Hydroxyindole-3-acetic Acid+urine-IL-9	Direct	urine_cometabolism	serum_cytokines	0.0405	0.906	no	dn	dn	no	no	no	DM-LS
[Ruminococcus]	IL-9	[Ruminococcus]+Transcriptional misregulation in cancer-Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.0679	0.906	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	IL-9	[Ruminococcus]+16:0/18:2-PI+blood+16:0/18:3-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.0679	0.906	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	IL-9	[Ruminococcus]-TCA+stool+18:0/18:0-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.0679	0.906	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	IL-9	[Ruminococcus]-TCA+stool+18:0/18:1-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.0679	0.906	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	IL-9	[Ruminococcus]-MUFA%+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.0679	0.906	no	no	dn	no	no	no	DM-LS
GUDCA+blood	IL-9	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-17A-IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.0766	0.906	no	no	dn	no	no	no	DM-LS
GUDCA+blood	IL-9	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.0766	0.906	no	no	dn	no	no	no	DM-LS
GUDCA+blood	IL-9	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-4-IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.0766	0.906	no	no	dn	no	no	no	DM-LS
Acetic acid+stool	IL-9	Acetic acid+stool-12-ketoDCA+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.0656	0.906	dn	no	no	no	no	no	DM-LS
Alistipes	IL-9	Alistipes+12-ketoDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.0114	0.906	no	up	no	no	no	no	DM-LS
Butyricimonas	IL-9	Butyricimonas-Prion disease-L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.17	0.906	no	no	no	no	no	no	DM-LS
Butyricimonas	IL-9	Butyricimonas-14:0/20:4-PC+blood+16:0/18:3-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.17	0.906	no	no	no	no	no	no	DM-LS
Butyricimonas	IL-9	Butyricimonas-GCA+blood+GDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.17	0.906	no	no	no	no	no	no	DM-LS
Butyricimonas	IL-9	Butyricimonas-14:0/20:4-PC+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.17	0.906	no	no	no	no	no	no	DM-LS
Butyricimonas	IL-9	Butyricimonas-14:0/20:4-PC+blood-GLCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.17	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Insulin resistance+L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-18:0+blood+L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-NF-kappa B signaling pathway-Hematopoietic cell lineage-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Signaling pathways regulating pluripotency of stem cells+DCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Breast cancer+DCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Gastric cancer+DCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Prolactin signaling pathway+DCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-AGE-RAGE signaling pathway in diabetic complications+DCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Neurotrophin signaling pathway-Toxoplasmosis-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Phosphatidylinositol signaling system-Influenza A-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Wnt signaling pathway-Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Insulin resistance-Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Prostate cancer-Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Phosphatidylinositol signaling system-Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Colorectal cancer+GLCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-LCA+stool+GLCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-HDCA+stool+HDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Wnt signaling pathway-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Signaling pathways regulating pluripotency of stem cells-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-RNA degradation-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Insulin resistance-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella+Parkinson disease-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Phosphatidylinositol signaling system-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Wnt signaling pathway-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Signaling pathways regulating pluripotency of stem cells-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-RNA degradation-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Spinocerebellar ataxia-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Long-term potentiation-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Insulin resistance-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Phosphatidylinositol signaling system-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-MAPK signaling pathway+Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Signaling pathways regulating pluripotency of stem cells+Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Colorectal cancer+Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Breast cancer+Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Spinocerebellar ataxia+Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Glioma+Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Choline metabolism in cancer+Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Central carbon metabolism in cancer+Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Gastric cancer+Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella+Arachidonic acid metabolism-Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-MicroRNAs in cancer+Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-ErbB signaling pathway+Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Phosphatidylinositol signaling system+Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Glioma+GCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Long-term potentiation+GCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Glioma+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella+Arachidonic acid metabolism-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-EPA+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Long-term potentiation+GCDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-LCA+stool+GDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
Collinsella	IL-9	Collinsella-Prolactin signaling pathway+GDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	IL-9	total_blood_scfa+blood+TUDCA+blood+Eotaxin+IL-4-IL-8-IL-9	Indirect	serum_scfa	serum_cytokines	0.168	0.906	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	IL-9	total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-8-IL-9	Indirect	serum_scfa	serum_cytokines	0.168	0.906	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	IL-9	total_blood_scfa+blood+TUDCA+blood+Eotaxin+IL-17A-IL-8-IL-9	Indirect	serum_scfa	serum_cytokines	0.168	0.906	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-9	[Eubacterium]-Influenza A-IL-9	Indirect	Genus	serum_cytokines	0.0692	0.906	no	no	no	no	no	no	DM-LS
LCA+stool	IL-9	LCA+stool+GLCA+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.314	0.906	no	no	no	no	no	no	DM-LS
LCA+stool	IL-9	LCA+stool+GDCA+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.314	0.906	no	no	no	no	no	no	DM-LS
Akkermansia	IL-9	Akkermansia+LCA+stool+GDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.23	0.906	no	no	no	no	no	no	DM-LS
Akkermansia	IL-9	Akkermansia+LCA+stool+GLCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.23	0.906	no	no	no	no	no	no	DM-LS
Akkermansia	IL-9	Akkermansia+Apoptosis+Influenza A-IL-9	Indirect	Genus	serum_cytokines	0.23	0.906	no	no	no	no	no	no	DM-LS
Akkermansia	IL-9	Akkermansia-4-hydroxybenzoic acid+stool-HDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.23	0.906	no	no	no	no	no	no	DM-LS
Akkermansia	IL-9	Akkermansia-L-Alanine+blood+L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.23	0.906	no	no	no	no	no	no	DM-LS
Akkermansia	IL-9	Akkermansia+Apoptosis+Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.23	0.906	no	no	no	no	no	no	DM-LS
Akkermansia	IL-9	Akkermansia+Apoptosis+Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.23	0.906	no	no	no	no	no	no	DM-LS
Akkermansia	IL-9	Akkermansia+Apoptosis+Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.23	0.906	no	no	no	no	no	no	DM-LS
Akkermansia	IL-9	Akkermansia+12-ketoDCA+stool+DCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.23	0.906	no	no	no	no	no	no	DM-LS
Bifidobacterium	IL-9	Bifidobacterium+d18:1-18:1-SM+blood-GDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.105	0.906	no	dn	no	no	no	no	DM-LS
Ruminococcus	IL-9	Ruminococcus+Type I diabetes mellitus+Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-9	Ruminococcus+Phagosome+Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-9	Ruminococcus+Cell adhesion molecules+Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-9	Ruminococcus+Autoimmune thyroid disease+Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-9	Ruminococcus+Cell adhesion molecules-L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-9	Ruminococcus+Type I diabetes mellitus+Influenza A-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-9	Ruminococcus+Endocytosis+Influenza A-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-9	Ruminococcus+Phagosome+Influenza A-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-9	Ruminococcus+Cell adhesion molecules+Influenza A-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-9	Ruminococcus-18:2/18:2-PC+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-9	Ruminococcus-18:2/18:1-PC+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-9	Ruminococcus+Phagosome+Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-9	Ruminococcus+Cell adhesion molecules+Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-9	Ruminococcus+Phagosome+Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-9	Ruminococcus+Cell adhesion molecules+Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	DM-LS
GCDCA+blood	IL-9	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4-IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.31	0.906	no	no	no	no	no	no	DM-LS
GCDCA+blood	IL-9	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.31	0.906	no	no	no	no	no	no	DM-LS
GCDCA+blood	IL-9	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.31	0.906	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-9	Succinivibrio-Phospholipase D signaling pathway-Longevity regulating pathway - multiple species-IL-9	Indirect	Genus	serum_cytokines	0.138	0.906	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-9	Succinivibrio-Phospholipase D signaling pathway-Hematopoietic cell lineage-IL-9	Indirect	Genus	serum_cytokines	0.138	0.906	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-9	Succinivibrio-Phospholipase D signaling pathway-Toxoplasmosis-IL-9	Indirect	Genus	serum_cytokines	0.138	0.906	no	no	no	no	no	no	DM-LS
ACA+blood	IL-9	ACA+blood-Eotaxin+IL-4-IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.338	0.906	no	no	no	no	no	no	DM-LS
ACA+blood	IL-9	ACA+blood-Eotaxin+IL-17A-IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.338	0.906	no	no	no	no	no	no	DM-LS
ACA+blood	IL-9	ACA+blood-Eotaxin-GM-CSF+IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.338	0.906	no	no	no	no	no	no	DM-LS
ACA+blood	IL-9	ACA+blood-DL-methionine sulfoxide+blood+EPA+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	serum_bileacids	serum_cytokines	0.338	0.906	no	no	no	no	no	no	DM-LS
ACA+blood	IL-9	ACA+blood+Glycine+blood+MUFA%+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	serum_bileacids	serum_cytokines	0.338	0.906	no	no	no	no	no	no	DM-LS
ACA+blood	IL-9	ACA+blood-DL-methionine sulfoxide+blood+L-Methionine+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	serum_bileacids	serum_cytokines	0.338	0.906	no	no	no	no	no	no	DM-LS
ACA+blood	IL-9	ACA+blood+Glycine+blood+L-Aspartic acid+blood+L-Glutamic acid+blood+IL-9	Indirect	serum_bileacids	serum_cytokines	0.338	0.906	no	no	no	no	no	no	DM-LS
DCA+stool	IL-9	DCA+stool-IL-9	Direct	stool_bileacids	serum_cytokines	0.195	0.906	no	no	no	no	no	no	DM-LS
2-hydroxyhippuric acid+urine	IL-9	2-hydroxyhippuric acid+urine+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	urine_cometabolism	serum_cytokines	0.215	0.906	no	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-9	Butyric acid+stool-12-ketoDCA+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.102	0.906	dn	no	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	IL-9	4-hydroxybenzoic acid+stool-HDCA+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.906	no	dn	no	no	no	no	DM-LS
GCA+blood	IL-9	GCA+blood+GDCA+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.16	0.906	no	no	no	no	no	no	DM-LS
ACA+stool	IL-9	ACA+stool-GCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.417	0.906	no	no	no	no	no	no	DM-LS
CDCA+blood	IL-9	CDCA+blood-MUFA%+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	serum_bileacids	serum_cytokines	0.506	0.906	no	no	no	no	no	no	DM-LS
CDCA+blood	IL-9	CDCA+blood-L-Methionine+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	serum_bileacids	serum_cytokines	0.506	0.906	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-9	capric acid C6+blood+MUFA%+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	serum_scfa	serum_cytokines	0.433	0.906	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-9	capric acid C6+blood-L-Alanine+blood+L-Glutamic acid+blood+IL-9	Indirect	serum_scfa	serum_cytokines	0.433	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter+Insulin resistance+L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter-Carbon metabolism+Toxoplasmosis-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter+HDCA+stool+HDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter-Lysosome+Influenza A-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter+Glucagon signaling pathway-Influenza A-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter+Glucagon signaling pathway+GCDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter+Insulin resistance-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter-Carbon metabolism+Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter-Lysosome+Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter+Glucagon signaling pathway-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter+Insulin resistance-Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter-Carbon metabolism+Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter-Lysosome+Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter+Glucagon signaling pathway-Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter+Small cell lung cancer-Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter+Pathways in cancer-Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter+Prostate cancer-Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter+Insulin resistance-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	"Pyramidobacter+Parathyroid hormone synthesis, secretion and action-Tuberculosis-IL-9"	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter-Carbon metabolism+Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter-Lysosome+Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-9	Pyramidobacter+Glucagon signaling pathway-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.45	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+cAMP signaling pathway-Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella-Glycolysis / Gluconeogenesis+Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella-Carbon metabolism+Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Calcium signaling pathway-Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Cushing syndrome-Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Cocaine addiction-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella-Glycolysis / Gluconeogenesis+Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Aldosterone synthesis and secretion-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Insulin secretion-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+GnRH signaling pathway-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Adrenergic signaling in cardiomyocytes-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Inflammatory mediator regulation of TRP channels-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella-Carbon metabolism+Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Cortisol synthesis and secretion-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Calcium signaling pathway-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Amphetamine addiction-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Dopaminergic synapse-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Cushing syndrome-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Melanogenesis-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+cAMP signaling pathway-Longevity regulating pathway - multiple species-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Phospholipase D signaling pathway-Longevity regulating pathway - multiple species-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella-Glycolysis / Gluconeogenesis+Longevity regulating pathway - multiple species-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Calcium signaling pathway-Longevity regulating pathway - multiple species-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+cAMP signaling pathway-Toxoplasmosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Cocaine addiction-Toxoplasmosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Phospholipase D signaling pathway-Toxoplasmosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella-Glycolysis / Gluconeogenesis+Toxoplasmosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Aldosterone synthesis and secretion-Toxoplasmosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Insulin secretion-Toxoplasmosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Adrenergic signaling in cardiomyocytes-Toxoplasmosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella-Carbon metabolism+Toxoplasmosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Cortisol synthesis and secretion-Toxoplasmosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Calcium signaling pathway-Toxoplasmosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Dopaminergic synapse-Toxoplasmosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Cushing syndrome-Toxoplasmosis-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Cocaine addiction-Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Endocrine and other factor-regulated calcium reabsorption-Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Long-term depression-Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella-Glycolysis / Gluconeogenesis+Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Aldosterone synthesis and secretion-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Adrenergic signaling in cardiomyocytes-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Inflammatory mediator regulation of TRP channels-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella-Carbon metabolism+Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Calcium signaling pathway-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Dopaminergic synapse-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Cushing syndrome-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Melanogenesis-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+cAMP signaling pathway-Hematopoietic cell lineage-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Phospholipase D signaling pathway-Hematopoietic cell lineage-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella-Glycolysis / Gluconeogenesis+Hematopoietic cell lineage-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+18:0-LPC+blood+18:0/18:1-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+L-Alanine+blood+L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+20:0+blood-HDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella-Proteasome+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+18:0-LPC+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Long-term depression-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Aldosterone synthesis and secretion+GCDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Adrenergic signaling in cardiomyocytes+GCDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
Prevotella	IL-9	Prevotella+Amphetamine addiction+GCDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	DM-LS
TCA+blood	IL-9	TCA+blood+FGF basic+IL-17A-IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.339	0.906	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-9	iso-DCA+blood+L-Leucine+blood+L-Methionine+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	serum_bileacids	serum_cytokines	0.38	0.906	no	no	no	no	no	no	DM-LS
HCA+stool	IL-9	HCA+stool+24:0+blood-GLCA+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.155	0.906	no	no	no	no	no	no	DM-LS
HCA+stool	IL-9	HCA+stool+24:0+blood-Hypotaurine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.155	0.906	no	no	no	no	no	no	DM-LS
Roseburia	IL-9	Roseburia+16:0/18:0-PS+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.495	0.906	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	IL-9	12-ketoDCA+stool+DCA+stool-IL-9	Indirect	stool_bileacids	serum_cytokines	0.505	0.906	no	no	no	no	no	no	DM-LS
4-Hydroxyphenylacetic acid+urine	IL-9	4-Hydroxyphenylacetic acid+urine-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	urine_cometabolism	serum_cytokines	0.0321	0.906	up	up	no	no	no	no	DM-LS
GLCA+blood	IL-9	GLCA+blood-IL-9	Direct	serum_bileacids	serum_cytokines	0.319	0.906	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	IL-9	L-Tryptophan+stool+Phenylacetic acid+stool+HDCA+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.557	0.906	no	no	no	no	no	no	DM-LS
CA+blood	IL-9	CA+blood-MUFA%+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	serum_bileacids	serum_cytokines	0.606	0.906	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IL-9	L-Phenylalanine+stool+16:0/18:0-PC+blood+18:0/18:1-PC+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.398	0.906	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IL-9	L-Phenylalanine+stool+16:0/18:0-PC+blood+18:0/18:0-PC+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.398	0.906	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IL-9	L-Phenylalanine+stool+L-Methionine+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.398	0.906	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IL-9	L-Phenylalanine+stool-18:0-LPE+blood-HDCA+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.398	0.906	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IL-9	L-Phenylalanine+stool+Phenylacetic acid+stool+HDCA+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.398	0.906	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	IL-9	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	serum_scfa	serum_cytokines	0.407	0.906	no	no	no	no	no	no	DM-LS
GCA+stool	IL-9	GCA+stool+IL-9	Direct	stool_bileacids	serum_cytokines	0.0809	0.906	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	IL-9	T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.478	0.906	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	IL-9	T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4-IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.478	0.906	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	IL-9	T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.478	0.906	no	no	no	no	no	no	DM-LS
Coprococcus	IL-9	Coprococcus+DCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-LS
Coprococcus	IL-9	Coprococcus-GCDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-LS
Coprococcus	IL-9	Coprococcus-16:0/18:3-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	DM-LS
Oscillospira	IL-9	Oscillospira-Adrenergic signaling in cardiomyocytes-Toxoplasmosis-IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	DM-LS
Oscillospira	IL-9	Oscillospira-Adrenergic signaling in cardiomyocytes-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	DM-LS
Oscillospira	IL-9	Oscillospira+Peroxisome+Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	DM-LS
Oscillospira	IL-9	Oscillospira+NOD-like receptor signaling pathway+DCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	DM-LS
Oscillospira	IL-9	Oscillospira-4-hydroxybenzoic acid+stool-HDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	DM-LS
Oscillospira	IL-9	Oscillospira+Peroxisome+Longevity regulating pathway - multiple species-IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	DM-LS
Oscillospira	IL-9	Oscillospira-Adrenergic signaling in cardiomyocytes+GCDCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	DM-LS
Oscillospira	IL-9	Oscillospira-Adrenergic signaling in cardiomyocytes-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	DM-LS
Oscillospira	IL-9	Oscillospira+Peroxisome+Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	DM-LS
HCA+blood	IL-9	HCA+blood-MUFA+blood+MUFA%+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	serum_bileacids	serum_cytokines	0.544	0.906	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-9	iso-LCA+stool+LCA+stool+GLCA+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.72	0.906	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-9	iso-LCA+stool+LCA+stool+GDCA+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.72	0.906	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-9	iso-LCA+stool+Phenylacetic acid+stool+HDCA+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.72	0.906	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-9	iso-LCA+stool-TCA+stool+18:0/18:1-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.72	0.906	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-9	iso-LCA+stool-TCA+stool+18:0/18:0-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.72	0.906	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	IL-9	2-methyl-butyric acid m-C4+blood-CA+blood-MUFA%+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	serum_scfa	serum_cytokines	0.262	0.906	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	IL-9	2-methyl-butyric acid m-C4+blood+isobutyric acid C4+blood+MUFA%+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	serum_scfa	serum_cytokines	0.262	0.906	no	no	no	no	no	no	DM-LS
DCA+blood	IL-9	DCA+blood+EPA+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	serum_bileacids	serum_cytokines	0.122	0.906	no	no	no	no	no	no	DM-LS
DCA+blood	IL-9	DCA+blood-MUFA%+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	serum_bileacids	serum_cytokines	0.122	0.906	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-9	3-(3-Hydroxyphenyl)propanoic acid+stool-16:0/18:0-PC+blood+18:0/18:0-PC+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.33	0.906	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-9	3-(3-Hydroxyphenyl)propanoic acid+stool-16:0/18:0-PC+blood+18:0/18:1-PC+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.33	0.906	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-9	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2/18:2-PC+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.33	0.906	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-9	3-(3-Hydroxyphenyl)propanoic acid+stool-18:3/18:2-PC+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.33	0.906	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-9	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2/18:1-PC+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.33	0.906	no	no	no	no	no	no	DM-LS
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-9	"3-(3,4-dihydroxyphenyl)propionic acid+urine-5-Hydroxyindole-3-acetic Acid+urine-IL-9"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.906	up	up	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IL-9	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+HDCA+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.304	0.906	no	no	no	no	no	no	DM-LS
TCA+stool	IL-9	TCA+stool+18:0/18:0-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.458	0.906	no	no	no	no	no	no	DM-LS
TCA+stool	IL-9	TCA+stool+18:0/18:1-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.458	0.906	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-9	HDCA+stool+HDCA+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.176	0.906	no	no	no	no	no	no	DM-LS
Lachnospira	IL-9	Lachnospira-Adherens junction+HDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-LS
Lachnospira	IL-9	Lachnospira+18:1/18:1-PC+blood-HDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-LS
Lachnospira	IL-9	Lachnospira+18:1/20:3-PC+blood-HDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-LS
Lachnospira	IL-9	Lachnospira+16:0/20:3-PC+blood-HDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-LS
Lachnospira	IL-9	Lachnospira-Adherens junction+Influenza A-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-LS
Lachnospira	IL-9	Lachnospira-Adherens junction-L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-LS
Lachnospira	IL-9	Lachnospira+18:0+blood+L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-LS
Lachnospira	IL-9	Lachnospira-Adherens junction+Hematopoietic cell lineage-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-LS
Lachnospira	IL-9	Lachnospira+18:1/18:1-PC+blood-GLCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-LS
Lachnospira	IL-9	Lachnospira+16:0/20:3-PC+blood-GLCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	DM-LS
Fusobacterium	IL-9	Fusobacterium-DCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.628	0.906	no	no	no	no	no	no	DM-LS
isobutyric acid C4+blood	IL-9	isobutyric acid C4+blood+MUFA%+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	serum_scfa	serum_cytokines	0.0151	0.906	up	up	no	no	no	no	DM-LS
GCDCA+stool	IL-9	GCDCA+stool+IL-9	Direct	stool_bileacids	serum_cytokines	0.0471	0.906	no	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-9	5-Hydroxytryptamine+stool-Acetic acid+stool-12-ketoDCA+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.906	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-9	5-Hydroxytryptamine+stool-Propionic acid+stool-18:0/18:1-PC+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.906	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-9	5-Hydroxytryptamine+stool-Propionic acid+stool-18:0/18:0-PC+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.906	dn	dn	no	no	no	no	DM-LS
Odoribacter	IL-9	Odoribacter+IL-8-IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-9	Isobutyric acid+stool+Phenylacetic acid+stool+HDCA+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.408	0.906	no	no	no	no	no	no	DM-LS
2-hydroxyphenylacetic acid+urine	IL-9	2-hydroxyphenylacetic acid+urine+4-Hydroxyphenylacetic acid+urine-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	urine_cometabolism	serum_cytokines	0.763	0.906	no	no	no	no	no	no	DM-LS
Lachnobacterium	IL-9	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-8-IL-9	Indirect	Genus	serum_cytokines	0.867	0.906	no	no	no	no	no	no	DM-LS
Lachnobacterium	IL-9	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin+IL-4-IL-8-IL-9	Indirect	Genus	serum_cytokines	0.867	0.906	no	no	no	no	no	no	DM-LS
Lachnobacterium	IL-9	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A-IL-8-IL-9	Indirect	Genus	serum_cytokines	0.867	0.906	no	no	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-9	Kynurenic acid+stool-nutriCA+stool-Phenylacetic acid+stool+HDCA+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.037	0.906	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-9	Kynurenic acid+stool+L-Tyrosine+stool+Phenylacetic acid+stool+HDCA+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.037	0.906	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-9	Kynurenic acid+stool+L-Tyrosine+stool-18:0-LPE+blood-HDCA+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.037	0.906	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-9	Kynurenic acid+stool+L-Tyrosine+stool-16:0/22:6-PE+blood-L-Glutamic acid+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.037	0.906	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-9	Kynurenic acid+stool+L-Tyrosine+stool-18:1/18:1-PE+blood-L-Glutamic acid+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.037	0.906	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-9	Kynurenic acid+stool-nutriCA+stool-18:0+blood+L-Glutamic acid+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.037	0.906	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-9	Kynurenic acid+stool-nutriCA+stool-TXB2+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.037	0.906	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-9	Kynurenic acid+stool+L-Tyrosine+stool+L-Methionine+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.037	0.906	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-9	Kynurenic acid+stool-UDCA+stool-16:0/18:0-PC+blood+18:0/18:0-PC+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.037	0.906	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-9	Kynurenic acid+stool+L-Tyrosine+stool+16:0/18:0-PC+blood+18:0/18:0-PC+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.037	0.906	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-9	Kynurenic acid+stool-UDCA+stool-16:0/18:0-PC+blood+18:0/18:1-PC+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.037	0.906	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-9	Kynurenic acid+stool+L-Tyrosine+stool+16:0/18:0-PC+blood+18:0/18:1-PC+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.037	0.906	dn	dn	no	no	no	no	DM-LS
Anaerostipes	IL-9	Anaerostipes-Non-small cell lung cancer+Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-9	Anaerostipes-Insulin resistance+L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-9	Anaerostipes-Insulin resistance-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-9	Anaerostipes-Insulin resistance-Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-9	Anaerostipes-Prostate cancer-Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-9	Anaerostipes-Insulin resistance-Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-9	Anaerostipes-Neurotrophin signaling pathway-Toxoplasmosis-IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-9	Anaerostipes-EPA+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	DM-LS
TUDCA+stool	IL-9	TUDCA+stool-UDCA+stool-16:0/18:0-PC+blood+18:0/18:1-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.241	0.906	no	no	no	no	no	no	DM-LS
TUDCA+stool	IL-9	TUDCA+stool-UDCA+stool-16:0/18:0-PC+blood+18:0/18:0-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.241	0.906	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-9	Isovaleric acid+stool+Phenylacetic acid+stool+HDCA+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.343	0.906	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-9	Paraprevotella+Glutathione metabolism-Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-9	Paraprevotella+Arachidonic acid metabolism-Hypotaurine+blood-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-9	Paraprevotella+Glutathione metabolism-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-9	Paraprevotella+Arachidonic acid metabolism-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	DM-LS
iso-LCA+blood	IL-9	"iso-LCA+blood+L-Ornithine+blood+L-Tryptophan+blood-3-(3,4-dihydroxyphenyl)propionic acid+urine-5-Hydroxyindole-3-acetic Acid+urine-IL-9"	Indirect	serum_bileacids	serum_cytokines	0.507	0.906	no	no	no	no	no	no	DM-LS
iso-LCA+blood	IL-9	iso-LCA+blood+L-Proline+blood-MUFA+blood+MUFA%+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	serum_bileacids	serum_cytokines	0.507	0.906	no	no	no	no	no	no	DM-LS
iso-LCA+blood	IL-9	iso-LCA+blood-Sarcosine+blood-FGF basic+IL-17A-IL-8-IL-9	Indirect	serum_bileacids	serum_cytokines	0.507	0.906	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool+HDCA+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	DM-LS
Gemmiger	IL-9	Gemmiger-GCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.595	0.906	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-9	GDCA+stool+18:0/18:0-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.656	0.906	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-9	GDCA+stool+18:0/18:1-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.656	0.906	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IL-9	Methanobrevibacter+TXB2+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.629	0.906	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IL-9	Methanobrevibacter+18:0-LPC+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.629	0.906	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IL-9	Methanobrevibacter+16:0/18:0-PC+blood+18:0/18:0-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.629	0.906	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IL-9	Methanobrevibacter+16:0/18:0-PC+blood+18:0/18:1-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.629	0.906	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IL-9	Methanobrevibacter+18:0-LPC+blood+18:0/18:1-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.629	0.906	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IL-9	Methanobrevibacter+L-Citrulline+blood+L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.629	0.906	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IL-9	Methanobrevibacter+L-2-Aminobutyric acid+blood+L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.629	0.906	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	IL-9	L-Tyrosine+stool+16:0/18:0-PC+blood+18:0/18:0-PC+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.44	0.906	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	IL-9	L-Tyrosine+stool+16:0/18:0-PC+blood+18:0/18:1-PC+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.44	0.906	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	IL-9	L-Tyrosine+stool+Phenylacetic acid+stool+HDCA+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.44	0.906	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	IL-9	L-Tyrosine+stool-18:0-LPE+blood-HDCA+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.44	0.906	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	IL-9	L-Tyrosine+stool-16:0/22:6-PE+blood-L-Glutamic acid+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.44	0.906	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	IL-9	L-Tyrosine+stool-18:1/18:1-PE+blood-L-Glutamic acid+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.44	0.906	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	IL-9	L-Tyrosine+stool+L-Methionine+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.44	0.906	no	no	no	no	no	no	DM-LS
CDCA+stool	IL-9	CDCA+stool+TCA+stool+18:0/18:1-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.663	0.906	no	no	no	no	no	no	DM-LS
CDCA+stool	IL-9	CDCA+stool+TCA+stool+18:0/18:0-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.663	0.906	no	no	no	no	no	no	DM-LS
CDCA+stool	IL-9	CDCA+stool-LCA+stool+GLCA+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.663	0.906	no	no	no	no	no	no	DM-LS
CDCA+stool	IL-9	CDCA+stool-LCA+stool+GDCA+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.663	0.906	no	no	no	no	no	no	DM-LS
CDCA+stool	IL-9	CDCA+stool-HDCA+stool+HDCA+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.663	0.906	no	no	no	no	no	no	DM-LS
CDCA+stool	IL-9	CDCA+stool-Phenylacetic acid+stool+HDCA+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.663	0.906	no	no	no	no	no	no	DM-LS
CA+stool	IL-9	CA+stool+TCA+stool+18:0/18:1-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.827	0.906	no	no	no	no	no	no	DM-LS
CA+stool	IL-9	CA+stool+TCA+stool+18:0/18:0-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.827	0.906	no	no	no	no	no	no	DM-LS
CA+stool	IL-9	CA+stool-Phenylacetic acid+stool+HDCA+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.827	0.906	no	no	no	no	no	no	DM-LS
CA+stool	IL-9	CA+stool-HDCA+stool+HDCA+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.827	0.906	no	no	no	no	no	no	DM-LS
CA+stool	IL-9	CA+stool-LCA+stool+GDCA+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.827	0.906	no	no	no	no	no	no	DM-LS
CA+stool	IL-9	CA+stool-LCA+stool+GLCA+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.827	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia-d18:1-18:1-SM+blood-GDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia-16:0/22:6-PE+blood-L-Glutamic acid+blood+IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia+18:2/18:2-PC+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia+18:2/18:1-PC+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia+18:1/18:2-PI+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia-Neutrophil extracellular trap formation+Rheumatoid arthritis-IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia+Primary immunodeficiency+HDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia+Platinum drug resistance-Influenza A-IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia-Neutrophil extracellular trap formation+Influenza A-IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia-Arginine and proline metabolism+Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia+Platinum drug resistance-Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia-Neutrophil extracellular trap formation+Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia-PPAR signaling pathway+Staphylococcus aureus infection-IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia-Arginine and proline metabolism+Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia-cGMP-PKG signaling pathway+Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia-Neutrophil extracellular trap formation+Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia-PPAR signaling pathway+Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia+14:0/18:2-PC+blood+16:0/18:3-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
Slackia	IL-9	Slackia+14:0/18:2-PC+blood-GLCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.94	0.906	no	no	no	no	no	no	DM-LS
HDCA+blood	IL-9	HDCA+blood-IL-9	Direct	serum_bileacids	serum_cytokines	0.483	0.906	no	no	no	no	no	no	DM-LS
UDCA+stool	IL-9	UDCA+stool-16:0/18:0-PC+blood+18:0/18:1-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.266	0.906	no	no	no	no	no	no	DM-LS
UDCA+stool	IL-9	UDCA+stool-16:0/18:0-PC+blood+18:0/18:0-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.266	0.906	no	no	no	no	no	no	DM-LS
TDCA+stool	IL-9	TDCA+stool+UDCA+stool-16:0/18:0-PC+blood+18:0/18:1-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.963	0.906	no	no	no	no	no	no	DM-LS
TDCA+stool	IL-9	TDCA+stool+UDCA+stool-16:0/18:0-PC+blood+18:0/18:0-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.963	0.906	no	no	no	no	no	no	DM-LS
nutriCA+stool	IL-9	nutriCA+stool-18:0+blood+L-Glutamic acid+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.481	0.906	no	no	no	no	no	no	DM-LS
nutriCA+stool	IL-9	nutriCA+stool-TXB2+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	stool_bileacids	serum_cytokines	0.481	0.906	no	no	no	no	no	no	DM-LS
nutriCA+stool	IL-9	nutriCA+stool-Phenylacetic acid+stool+HDCA+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.481	0.906	no	no	no	no	no	no	DM-LS
GDCA+blood	IL-9	GDCA+blood-IL-9	Direct	serum_bileacids	serum_cytokines	0.632	0.906	no	no	no	no	no	no	DM-LS
acetic acid C2+blood	IL-9	acetic acid C2+blood-L-Alanine+blood+L-Glutamic acid+blood+IL-9	Indirect	serum_scfa	serum_cytokines	0.000193	0.906	up	dn	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	IL-9	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-4-IL-8-IL-9	Indirect	serum_scfa	serum_cytokines	0.117	0.906	no	no	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	IL-9	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-8-IL-9	Indirect	serum_scfa	serum_cytokines	0.117	0.906	no	no	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	IL-9	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-17A-IL-8-IL-9	Indirect	serum_scfa	serum_cytokines	0.117	0.906	no	no	no	no	no	no	DM-LS
Adlercreutzia	IL-9	Adlercreutzia-EPA+blood+5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.548	0.906	no	no	no	no	no	no	DM-LS
Adlercreutzia	IL-9	Adlercreutzia+18:0-LPC+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.548	0.906	no	no	no	no	no	no	DM-LS
Adlercreutzia	IL-9	Adlercreutzia-14:0+blood+16:0/18:3-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.548	0.906	no	no	no	no	no	no	DM-LS
Adlercreutzia	IL-9	Adlercreutzia+16:0/18:0-PC+blood+18:0/18:0-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.548	0.906	no	no	no	no	no	no	DM-LS
Adlercreutzia	IL-9	Adlercreutzia+18:0-LPC+blood+18:0/18:1-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.548	0.906	no	no	no	no	no	no	DM-LS
Adlercreutzia	IL-9	Adlercreutzia+16:0/18:0-PC+blood+18:0/18:1-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.548	0.906	no	no	no	no	no	no	DM-LS
Clostridium	IL-9	Clostridium+cGMP-PKG signaling pathway+Tuberculosis-IL-9	Indirect	Genus	serum_cytokines	0.925	0.906	no	no	no	no	no	no	DM-LS
Clostridium	IL-9	Clostridium-Butyric acid+stool-12-ketoDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.925	0.906	no	no	no	no	no	no	DM-LS
 Clostridium	IL-9	Clostridium+Butyric acid+stool-12-ketoDCA+blood-IL-9	Indirect	Genus	serum_cytokines	NA	0.906	NA	NA	NA	no	no	no	DM-LS
Clostridium	IL-9	Clostridium-Butyric acid+stool-12-ketoDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.925	0.906	no	no	no	no	no	no	DM-LS
 Clostridium	IL-9	Clostridium+Butyric acid+stool-12-ketoDCA+blood-IL-9	Indirect	Genus	serum_cytokines	NA	0.906	NA	NA	NA	no	no	no	DM-LS
Clostridium	IL-9	Clostridium-Acetic acid+stool-12-ketoDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.925	0.906	no	no	no	no	no	no	DM-LS
 Clostridium	IL-9	Clostridium+Acetic acid+stool-12-ketoDCA+blood-IL-9	Indirect	Genus	serum_cytokines	NA	0.906	NA	NA	NA	no	no	no	DM-LS
Clostridium	IL-9	Clostridium-Acetic acid+stool-12-ketoDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.925	0.906	no	no	no	no	no	no	DM-LS
 Clostridium	IL-9	Clostridium+Acetic acid+stool-12-ketoDCA+blood-IL-9	Indirect	Genus	serum_cytokines	NA	0.906	NA	NA	NA	no	no	no	DM-LS
Clostridium	IL-9	Clostridium-14:0/16:0-PC+blood+16:0/18:3-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.925	0.906	no	no	no	no	no	no	DM-LS
Clostridium	IL-9	Clostridium-14:0/20:4-PC+blood+16:0/18:3-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.925	0.906	no	no	no	no	no	no	DM-LS
Clostridium	IL-9	Clostridium-14:0/18:2-PC+blood+16:0/18:3-PC+blood+IL-9	Indirect	Genus	serum_cytokines	0.925	0.906	no	no	no	no	no	no	DM-LS
Clostridium	IL-9	Clostridium-14:0/20:4-PC+blood-5-Hydroxyindole-3-acetic Acid+urine-IL-9	Indirect	Genus	serum_cytokines	0.925	0.906	no	no	no	no	no	no	DM-LS
Clostridium	IL-9	Clostridium-14:0/16:0-PC+blood-GLCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.925	0.906	no	no	no	no	no	no	DM-LS
Clostridium	IL-9	Clostridium-14:0/20:4-PC+blood-GLCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.925	0.906	no	no	no	no	no	no	DM-LS
Clostridium	IL-9	Clostridium-14:0/18:2-PC+blood-GLCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.925	0.906	no	no	no	no	no	no	DM-LS
Clostridium	IL-9	Clostridium-14:0/16:0-PC+blood-HDCA+blood-IL-9	Indirect	Genus	serum_cytokines	0.925	0.906	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-9	T-¦Á-MCA+stool-TCA+stool+18:0/18:0-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.48	0.906	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-9	T-¦Á-MCA+stool-TCA+stool+18:0/18:1-PC+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.48	0.906	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-9	12-ketoDCA+blood-IL-9	Direct	serum_bileacids	serum_cytokines	0.517	0.906	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-9	Butyricicoccus+DCA+stool-IL-9	Indirect	Genus	serum_cytokines	0.852	0.906	no	no	no	no	no	no	DM-LS
Blautia	Leptin	Blautia+d18:1-16:1-SM+blood-L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	1.36E-05	0.706	up	dn	dn	no	no	no	DM-LS
Blautia	Leptin	Blautia+14:0/20:4-PC+blood-L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	1.36E-05	0.706	up	dn	dn	no	no	no	DM-LS
Blautia	Leptin	Blautia+GUDCA+blood+UDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	1.36E-05	0.706	up	dn	dn	no	no	no	DM-LS
Blautia	Leptin	Blautia+d18:1-16:1-SM+blood-L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	1.36E-05	0.706	up	dn	dn	no	no	no	DM-LS
Blautia	Leptin	Blautia-L-Ornithine+blood+L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	1.36E-05	0.706	up	dn	dn	no	no	no	DM-LS
Blautia	Leptin	Blautia+14:0/20:4-PC+blood+18:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	1.36E-05	0.706	up	dn	dn	no	no	no	DM-LS
Blautia	Leptin	Blautia+14:0/20:4-PC+blood-GLCA+blood-Leptin	Indirect	Genus	DM-associated hormones	1.36E-05	0.706	up	dn	dn	no	no	no	DM-LS
Blautia	Leptin	Blautia-iso-LCA+blood-Sarcosine+blood+Leptin	Indirect	Genus	DM-associated hormones	1.36E-05	0.706	up	dn	dn	no	no	no	DM-LS
Parabacteroides	Leptin	Parabacteroides+20:0+blood+Sarcosine+blood+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	DM-LS
Parabacteroides	Leptin	Parabacteroides-Central carbon metabolism in cancer+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	DM-LS
Parabacteroides	Leptin	Parabacteroides-Glucagon signaling pathway-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	DM-LS
Parabacteroides	Leptin	Parabacteroides-EGFR tyrosine kinase inhibitor resistance-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	DM-LS
Parabacteroides	Leptin	Parabacteroides+Apoptosis+Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	DM-LS
Parabacteroides	Leptin	Parabacteroides+Complement and coagulation cascades+Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	DM-LS
Parabacteroides	Leptin	Parabacteroides-Glucagon signaling pathway+Cocaine addiction+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	DM-LS
Parabacteroides	Leptin	Parabacteroides-Glucagon signaling pathway+GCDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	DM-LS
Parabacteroides	Leptin	Parabacteroides-GCA+stool+GCDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	DM-LS
Parabacteroides	Leptin	Parabacteroides+Ethanolamine+blood+L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	DM-LS
Parabacteroides	Leptin	Parabacteroides+L-Leucine+blood+L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	DM-LS
Parabacteroides	Leptin	Parabacteroides+L-Isoleucine+blood+L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	DM-LS
Parabacteroides	Leptin	Parabacteroides+Ethanolamine+blood+L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	DM-LS
Parabacteroides	Leptin	Parabacteroides+L-Leucine+blood+L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	DM-LS
Parabacteroides	Leptin	Parabacteroides+L-Isoleucine+blood+L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	DM-LS
Dorea	Leptin	Dorea-Lipid and atherosclerosis-14:0/20:4-PC+blood-GLCA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-18:0/22:6-PE+blood+18:1/20:4-PE+blood+GLCA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-Lipid and atherosclerosis-14:0/18:2-PC+blood-GLCA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea+d18:1-20:0-SM+blood+GPC+blood-UDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-Lipid and atherosclerosis+18:1+blood-HCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-18:0/22:6-PE+blood+20:2/18:1-PE+blood-L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-18:0/22:6-PE+blood+18:1/18:0-PE+blood-L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-18:0/22:6-PE+blood-20:1+blood+L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-18:0/22:6-PE+blood-L-2-Aminobutyric acid+blood+L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-18:0/22:6-PE+blood+18:1/18:1-PE+blood-L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-Lipid and atherosclerosis+18:1/18:1-PE+blood-L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-Lipid and atherosclerosis+16:0/22:6-PE+blood-L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-18:0/22:6-PE+blood+18:1/16:1-PE+blood-L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-18:0/22:6-PE+blood+18:3/16:0-PE+blood-L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-Lipid and atherosclerosis-14:0/20:4-PC+blood-L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-Lipid and atherosclerosis-14:0/20:4-PC+blood+18:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-18:0/22:6-PE+blood+18:3/16:0-PE+blood+18:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-18:0/22:6-PE+blood+20:2/18:1-PE+blood-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-18:0/22:6-PE+blood+18:1/18:0-PE+blood-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-18:0/22:6-PE+blood-18:1-LPC+blood+Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-Lipid and atherosclerosis-14:0/18:2-PC+blood-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-18:0/22:6-PE+blood+18:1/18:1-PE+blood-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-Lipid and atherosclerosis+18:1/18:1-PE+blood-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-Lipid and atherosclerosis+16:1+blood-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-18:0/22:6-PE+blood+18:1/16:1-PE+blood-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-18:0/22:6-PE+blood+18:3/16:0-PE+blood-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-18:0/22:6-PE+blood+20:2/18:3-PE+blood-CDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-Lipid and atherosclerosis+18:1+blood-CDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea+d18:1-20:0-SM+blood+GPC+blood+L-Homocystine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-Lipid and atherosclerosis-14:0/18:2-PC+blood+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Dorea	Leptin	Dorea-Lipid and atherosclerosis-14:0/18:2-PC+blood+16:0/16:1-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	DM-LS
Faecalibacterium	Leptin	Faecalibacterium+Leptin	Direct	Genus	DM-associated hormones	0.0039	0.706	no	dn	dn	no	no	no	DM-LS
Bacteroides	Leptin	"Bacteroides-9,10-EPOME+blood+L-Citrulline+blood-Leptin"	Indirect	Genus	DM-associated hormones	0.000267	0.706	dn	dn	up	no	no	no	DM-LS
Bacteroides	Leptin	Bacteroides+Cytokine-cytokine receptor interaction-L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.000267	0.706	dn	dn	up	no	no	no	DM-LS
Bacteroides	Leptin	Bacteroides-GCA+stool+GCDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.000267	0.706	dn	dn	up	no	no	no	DM-LS
Bacteroides	Leptin	Bacteroides+22:6n3+blood-L-Homocystine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.000267	0.706	dn	dn	up	no	no	no	DM-LS
Propionic acid+stool	Leptin	Propionic acid+stool-18:0/18:0-PC+blood-UDCA+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.706	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	Leptin	Propionic acid+stool-18:0/18:1-PC+blood-UDCA+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.706	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	Leptin	Propionic acid+stool+16:0/20:5-PC+blood+CDCA+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.706	dn	no	up	no	no	no	DM-LS
[Ruminococcus]	Leptin	[Ruminococcus]+16:0/20:4-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.0679	0.706	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	Leptin	[Ruminococcus]+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.0679	0.706	no	no	dn	no	no	no	DM-LS
GUDCA+blood	Leptin	GUDCA+blood+UDCA+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.706	no	no	dn	no	no	no	DM-LS
UDCA+blood	Leptin	UDCA+blood+Leptin	Direct	serum_bileacids	DM-associated hormones	0.0939	0.706	no	no	dn	no	no	no	DM-LS
Acetic acid+stool	Leptin	Acetic acid+stool+Butyric acid+stool-Leptin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.706	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	Leptin	Acetic acid+stool+18:3n6+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.706	dn	no	no	no	no	no	DM-LS
Alistipes	Leptin	Alistipes+12-ketoDCA+blood+GLCA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.0114	0.706	no	up	no	no	no	no	DM-LS
Alistipes	Leptin	Alistipes-L-Arginine+blood+L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.0114	0.706	no	up	no	no	no	no	DM-LS
Alistipes	Leptin	Alistipes-GUDCA+blood+UDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.0114	0.706	no	up	no	no	no	no	DM-LS
Butyricimonas	Leptin	Butyricimonas+L-Lysine+blood+L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-LS
Butyricimonas	Leptin	Butyricimonas+L-Histidine+blood+L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-LS
Butyricimonas	Leptin	Butyricimonas-14:0/20:4-PC+blood+18:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-LS
Butyricimonas	Leptin	Butyricimonas-14:0/20:4-PC+blood-GLCA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-LS
Butyricimonas	Leptin	Butyricimonas-14:0/20:4-PC+blood-L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-LS
Butyricimonas	Leptin	Butyricimonas+L-Histidine+blood+L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-LS
Butyricimonas	Leptin	Butyricimonas-Cardiac muscle contraction+CDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	"Collinsella-9,10-EPOME+blood+L-Citrulline+blood-Leptin"	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Spinocerebellar ataxia+L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Phosphatidylinositol signaling system+L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Hepatitis B+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Prostate cancer+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-NF-kappa B signaling pathway+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Neurotrophin signaling pathway+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella+Parkinson disease+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Neurotrophin signaling pathway+Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella+Parkinson disease+Cocaine addiction+Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Colorectal cancer+GLCA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-LCA+stool+GLCA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Spinocerebellar ataxia+L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Hepatitis B+16:0/20:4-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Prostate cancer+16:0/20:4-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Neurotrophin signaling pathway+16:0/20:4-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-MAPK signaling pathway+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Signaling pathways regulating pluripotency of stem cells+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Colorectal cancer+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Breast cancer+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Spinocerebellar ataxia+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Glioma+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Choline metabolism in cancer+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Central carbon metabolism in cancer+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Gastric cancer+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella+Arachidonic acid metabolism-Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-MicroRNAs in cancer+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-ErbB signaling pathway+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Phosphatidylinositol signaling system+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Long-term potentiation-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
Collinsella	Leptin	Collinsella-Long-term potentiation+GCDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	DM-LS
[Eubacterium]	Leptin	[Eubacterium]+p53 signaling pathway-Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.0692	0.706	no	no	no	no	no	no	DM-LS
[Eubacterium]	Leptin	[Eubacterium]-Phagosome+Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.0692	0.706	no	no	no	no	no	no	DM-LS
[Eubacterium]	Leptin	[Eubacterium]-Viral myocarditis-L-Homocystine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.0692	0.706	no	no	no	no	no	no	DM-LS
[Eubacterium]	Leptin	[Eubacterium]-Viral myocarditis-L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.0692	0.706	no	no	no	no	no	no	DM-LS
[Eubacterium]	Leptin	[Eubacterium]-Phagosome-L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.0692	0.706	no	no	no	no	no	no	DM-LS
[Eubacterium]	Leptin	[Eubacterium]-Salmonella infection-16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.0692	0.706	no	no	no	no	no	no	DM-LS
[Eubacterium]	Leptin	[Eubacterium]-Salmonella infection-16:0/16:1-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.0692	0.706	no	no	no	no	no	no	DM-LS
[Eubacterium]	Leptin	[Eubacterium]-Salmonella infection+GLCA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.0692	0.706	no	no	no	no	no	no	DM-LS
[Eubacterium]	Leptin	[Eubacterium]-Fluid shear stress and atherosclerosis+Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.0692	0.706	no	no	no	no	no	no	DM-LS
[Eubacterium]	Leptin	[Eubacterium]-Pathogenic Escherichia coli infection+Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.0692	0.706	no	no	no	no	no	no	DM-LS
[Eubacterium]	Leptin	[Eubacterium]-Salmonella infection+Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.0692	0.706	no	no	no	no	no	no	DM-LS
LCA+stool	Leptin	LCA+stool+GLCA+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.706	no	no	no	no	no	no	DM-LS
Akkermansia	Leptin	Akkermansia+Apoptosis+Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	DM-LS
Akkermansia	Leptin	Akkermansia+LCA+stool+GLCA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	DM-LS
Akkermansia	Leptin	Akkermansia-L-Alanine+blood+Sarcosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	DM-LS
Akkermansia	Leptin	Akkermansia-Retrograde endocannabinoid signaling+CDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium+Glycine+blood+L-Glutamine+blood+L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium+Chemical carcinogenesis - receptor activation-L-Glutamine+blood+L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium+d18:1-18:1-SM+blood-L-Ornithine+blood+L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium+Glycine+blood+L-Asparagine+blood+L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium+Chemical carcinogenesis - receptor activation-UDCA+stool+UDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium-18:2/20:4-PC+blood+20:0-LPC+blood+L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium+Glycine+blood+L-Arginine+blood+L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium+Glycine+blood+L-Asparagine+blood+L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium+Chemical carcinogenesis - receptor activation-UDCA+stool+18:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium+Chemical carcinogenesis - receptor activation-UDCA+stool+CDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium-18:2/20:4-PC+blood+20:0/20:5-PC+blood-CDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium-18:2/20:4-PC+blood+20:2/18:3-PE+blood-CDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium+Glycine+blood+L-Asparagine+blood+L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium-18:2/20:4-PC+blood+20:1-LPE+blood-GLCA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium+Chemical carcinogenesis - receptor activation+Small cell lung cancer+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium+Chemical carcinogenesis - receptor activation+Small cell lung cancer+16:0/20:4-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium+Chemical carcinogenesis - receptor activation-UDCA+stool-L-Homocystine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Bifidobacterium	Leptin	Bifidobacterium-18:2/20:4-PC+blood+20:0-LPE+blood+L-Homocystine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	DM-LS
Ruminococcus	Leptin	Ruminococcus-L-Homocystine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.335	0.706	no	no	no	no	no	no	DM-LS
GCDCA+blood	Leptin	GCDCA+blood+GUDCA+blood+UDCA+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.706	no	no	no	no	no	no	DM-LS
GCDCA+blood	Leptin	GCDCA+blood-T-a-MCA+blood-UDCA+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.706	no	no	no	no	no	no	DM-LS
Succinivibrio	Leptin	Succinivibrio-L-Tyrosine+stool+L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	0.138	0.706	no	no	no	no	no	no	DM-LS
Succinivibrio	Leptin	Succinivibrio-L-Phenylalanine+stool+L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	0.138	0.706	no	no	no	no	no	no	DM-LS
Succinivibrio	Leptin	Succinivibrio-L-Tyrosine+stool+L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.138	0.706	no	no	no	no	no	no	DM-LS
Succinivibrio	Leptin	Succinivibrio-L-Phenylalanine+stool+L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.138	0.706	no	no	no	no	no	no	DM-LS
Succinivibrio	Leptin	Succinivibrio-L-Tyrosine+stool-18:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.138	0.706	no	no	no	no	no	no	DM-LS
Succinivibrio	Leptin	Succinivibrio-L-Phenylalanine+stool-18:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.138	0.706	no	no	no	no	no	no	DM-LS
Succinivibrio	Leptin	Succinivibrio-Phospholipase D signaling pathway+Cocaine addiction+Leptin	Indirect	Genus	DM-associated hormones	0.138	0.706	no	no	no	no	no	no	DM-LS
ACA+blood	Leptin	ACA+blood-DL-methionine sulfoxide+blood+L-Methionine+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.706	no	no	no	no	no	no	DM-LS
DCA+stool	Leptin	DCA+stool+18:1/18:1-PE+blood-L-Citrulline+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-LS
DCA+stool	Leptin	DCA+stool+iso-LCA+stool-Sarcosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-LS
DCA+stool	Leptin	DCA+stool-16:0/20:3-PC+blood+Sarcosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-LS
DCA+stool	Leptin	DCA+stool-18:1/18:1-PC+blood+Sarcosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-LS
DCA+stool	Leptin	"DCA+stool+12,13-EPOME+blood+GLCA+blood-Leptin"	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-LS
DCA+stool	Leptin	DCA+stool-16:0/20:3-PC+blood-GLCA+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-LS
DCA+stool	Leptin	DCA+stool-18:1/18:1-PC+blood-GLCA+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-LS
DCA+stool	Leptin	DCA+stool+LCA+stool+GLCA+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-LS
DCA+stool	Leptin	DCA+stool-GCA+stool+GCDCA+stool+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-LS
DCA+stool	Leptin	"DCA+stool+12,13-EPOME+blood+Hypotaurine+blood-Leptin"	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-LS
DCA+stool	Leptin	DCA+stool+iso-LCA+stool-18:3n6+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-LS
DCA+stool	Leptin	DCA+stool+iso-LCA+stool-CDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-LS
DCA+stool	Leptin	DCA+stool-18:1/18:1-PC+blood-CDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-LS
DCA+stool	Leptin	DCA+stool+iso-LCA+stool-UDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-LS
DCA+stool	Leptin	DCA+stool+18:1/18:1-PE+blood-Betaine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	DM-LS
Butyric acid+stool	Leptin	Butyric acid+stool-Leptin	Direct	stool_scfa	DM-associated hormones	0.102	0.706	dn	no	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	Leptin	4-hydroxybenzoic acid+stool+L-Asparagine+blood+L-Methionine+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.706	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	Leptin	4-hydroxybenzoic acid+stool-Phenylacetic acid+stool-Sarcosine+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.706	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	Leptin	4-hydroxybenzoic acid+stool-HDCA+blood-Sarcosine+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.706	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	Leptin	4-hydroxybenzoic acid+stool+L-Asparagine+blood+L-Citrulline+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.706	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	Leptin	4-hydroxybenzoic acid+stool+L-Asparagine+blood+L-Tryptophan+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.706	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	Leptin	4-hydroxybenzoic acid+stool+nutriCA+stool+HCA+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.706	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	Leptin	4-hydroxybenzoic acid+stool+CDCA+stool+HCA+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.706	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	Leptin	4-hydroxybenzoic acid+stool+nutriCA+stool+UDCA+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.706	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	Leptin	4-hydroxybenzoic acid+stool-nutriCA+blood+UDCA+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.706	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	Leptin	4-hydroxybenzoic acid+stool-Phenylacetic acid+stool-18:3n6+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.706	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	Leptin	4-hydroxybenzoic acid+stool+CDCA+stool+18:3n6+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.706	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	Leptin	"4-hydroxybenzoic acid+stool-12,13-EPOME+blood+Hypotaurine+blood-Leptin"	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.706	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	Leptin	"4-hydroxybenzoic acid+stool-12,13-EPOME+blood+GLCA+blood-Leptin"	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.706	no	dn	no	no	no	no	DM-LS
GCA+blood	Leptin	GCA+blood+GUDCA+blood+UDCA+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.706	no	no	no	no	no	no	DM-LS
ACA+stool	Leptin	ACA+stool+Sarcosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.706	no	no	no	no	no	no	DM-LS
ACA+stool	Leptin	ACA+stool-L-Citrulline+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.706	no	no	no	no	no	no	DM-LS
CDCA+blood	Leptin	CDCA+blood+Leptin	Direct	serum_bileacids	DM-associated hormones	0.506	0.706	no	no	no	no	no	no	DM-LS
capric acid C6+blood	Leptin	capric acid C6+blood-Sarcosine+blood+Leptin	Indirect	serum_scfa	DM-associated hormones	0.433	0.706	no	no	no	no	no	no	DM-LS
capric acid C6+blood	Leptin	capric acid C6+blood-CDCA+blood+Leptin	Indirect	serum_scfa	DM-associated hormones	0.433	0.706	no	no	no	no	no	no	DM-LS
capric acid C6+blood	Leptin	capric acid C6+blood+L-Tryptophan+blood-Leptin	Indirect	serum_scfa	DM-associated hormones	0.433	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	"Pyramidobacter+Parathyroid hormone synthesis, secretion and action+Cocaine addiction+Leptin"	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	Pyramidobacter-Carbon metabolism-Cocaine addiction+Leptin	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	Pyramidobacter+Glucagon signaling pathway+Cocaine addiction+Leptin	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	"Pyramidobacter+Parathyroid hormone synthesis, secretion and action-Betaine+blood-Leptin"	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	Pyramidobacter-Carbon metabolism+Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	Pyramidobacter-Lysosome+Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	Pyramidobacter+Glucagon signaling pathway-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	Pyramidobacter-Carbon metabolism-16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	Pyramidobacter+Small cell lung cancer+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	Pyramidobacter+Prostate cancer+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	Pyramidobacter+Pathways in cancer-Butyric acid+stool-Leptin	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	Pyramidobacter+Glucagon signaling pathway+GCDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	Pyramidobacter+Pathways in cancer+L-Homocystine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	Pyramidobacter-Carbon metabolism-CDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	Pyramidobacter+Ethanolamine+blood+L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	Pyramidobacter+Ethanolamine+blood+L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	"Pyramidobacter+Parathyroid hormone synthesis, secretion and action+16:0/20:4-PI+blood+Leptin"	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	Pyramidobacter-Carbon metabolism-16:0/20:4-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	Pyramidobacter+Small cell lung cancer+16:0/20:4-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Pyramidobacter	Leptin	Pyramidobacter+Prostate cancer+16:0/20:4-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	DM-LS
Prevotella	Leptin	Prevotella+Cocaine addiction+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	DM-LS
iso-DCA+blood	Leptin	iso-DCA+blood+L-Leucine+blood+L-Methionine+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.706	no	no	no	no	no	no	DM-LS
iso-DCA+blood	Leptin	iso-DCA+blood+L-Lysine+blood+L-Tryptophan+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.706	no	no	no	no	no	no	DM-LS
iso-DCA+blood	Leptin	iso-DCA+blood+L-Leucine+blood+L-Tryptophan+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.706	no	no	no	no	no	no	DM-LS
HCA+stool	Leptin	HCA+stool+UDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.706	no	no	no	no	no	no	DM-LS
HCA+stool	Leptin	HCA+stool+CDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.706	no	no	no	no	no	no	DM-LS
HCA+stool	Leptin	HCA+stool-L-Homocystine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.706	no	no	no	no	no	no	DM-LS
Roseburia	Leptin	Roseburia+HCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Leptin	12-ketoDCA+stool+16:0/22:6-PE+blood-L-Citrulline+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.706	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Leptin	12-ketoDCA+stool+18:1/18:1-PE+blood-L-Citrulline+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.706	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Leptin	12-ketoDCA+stool+18:1/18:1-PE+blood-Betaine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.706	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Leptin	12-ketoDCA+stool+iso-LCA+stool-CDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.706	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Leptin	12-ketoDCA+stool+iso-LCA+stool-18:3n6+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.706	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Leptin	12-ketoDCA+stool+LCA+stool+GLCA+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.706	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Leptin	12-ketoDCA+stool+iso-LCA+stool-Sarcosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.706	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Leptin	12-ketoDCA+stool-L-Alanine+blood+Sarcosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.706	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Leptin	12-ketoDCA+stool+iso-LCA+stool-UDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.706	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	Leptin	12-ketoDCA+stool-GUDCA+blood+UDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.706	no	no	no	no	no	no	DM-LS
GLCA+blood	Leptin	GLCA+blood-Leptin	Direct	serum_bileacids	DM-associated hormones	0.319	0.706	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	Leptin	L-Tryptophan+stool+L-Tryptophan+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.706	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	Leptin	L-Tryptophan+stool-18:3n6+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.706	no	no	no	no	no	no	DM-LS
CA+blood	Leptin	CA+blood+HCA+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.706	no	no	no	no	no	no	DM-LS
CA+blood	Leptin	CA+blood+CDCA+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.706	no	no	no	no	no	no	DM-LS
CA+blood	Leptin	CA+blood+UDCA+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.706	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	Leptin	L-Phenylalanine+stool+L-Methionine+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.706	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	Leptin	L-Phenylalanine+stool+L-Tryptophan+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.706	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	Leptin	L-Phenylalanine+stool-18:3n6+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.706	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	Leptin	butyric acid C4+blood+isobutyric acid C4+blood+isovaleric acid iso-C5+blood-UDCA+blood+Leptin	Indirect	serum_scfa	DM-associated hormones	0.407	0.706	no	no	no	no	no	no	DM-LS
GCA+stool	Leptin	GCA+stool+GCDCA+stool+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.706	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	Leptin	T-a-MCA+blood-UDCA+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.478	0.706	no	no	no	no	no	no	DM-LS
Coprococcus	Leptin	Coprococcus-GCDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.612	0.706	no	no	no	no	no	no	DM-LS
Coprococcus	Leptin	Coprococcus-CDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.612	0.706	no	no	no	no	no	no	DM-LS
Coprococcus	Leptin	Coprococcus+Butyric acid+stool-Leptin	Indirect	Genus	DM-associated hormones	0.612	0.706	no	no	no	no	no	no	DM-LS
Coprococcus	Leptin	Coprococcus-HCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.612	0.706	no	no	no	no	no	no	DM-LS
Coprococcus	Leptin	Coprococcus+Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.612	0.706	no	no	no	no	no	no	DM-LS
Oscillospira	Leptin	Oscillospira-CDCA+stool+HCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.62	0.706	no	no	no	no	no	no	DM-LS
Oscillospira	Leptin	Oscillospira-nutriCA+stool+HCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.62	0.706	no	no	no	no	no	no	DM-LS
Oscillospira	Leptin	Oscillospira-Adrenergic signaling in cardiomyocytes+HCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.62	0.706	no	no	no	no	no	no	DM-LS
Oscillospira	Leptin	Oscillospira-Adrenergic signaling in cardiomyocytes+Cocaine addiction+Leptin	Indirect	Genus	DM-associated hormones	0.62	0.706	no	no	no	no	no	no	DM-LS
Oscillospira	Leptin	Oscillospira-Adrenergic signaling in cardiomyocytes-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.62	0.706	no	no	no	no	no	no	DM-LS
Oscillospira	Leptin	Oscillospira-Alzheimer disease-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.62	0.706	no	no	no	no	no	no	DM-LS
Oscillospira	Leptin	Oscillospira-Adrenergic signaling in cardiomyocytes+GCDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.62	0.706	no	no	no	no	no	no	DM-LS
Oscillospira	Leptin	Oscillospira-nutriCA+stool+UDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.62	0.706	no	no	no	no	no	no	DM-LS
Oscillospira	Leptin	Oscillospira-CDCA+stool+18:3n6+blood+Leptin	Indirect	Genus	DM-associated hormones	0.62	0.706	no	no	no	no	no	no	DM-LS
HCA+blood	Leptin	HCA+blood+Leptin	Direct	serum_bileacids	DM-associated hormones	0.544	0.706	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Leptin	iso-LCA+stool-CDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.706	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Leptin	iso-LCA+stool-UDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.706	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Leptin	iso-LCA+stool-18:3n6+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.706	no	no	no	no	no	no	DM-LS
iso-LCA+stool	Leptin	iso-LCA+stool-Sarcosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.706	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	Leptin	2-methyl-butyric acid m-C4+blood-CA+blood+CDCA+blood+Leptin	Indirect	serum_scfa	DM-associated hormones	0.262	0.706	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	Leptin	2-methyl-butyric acid m-C4+blood-CA+blood+HCA+blood+Leptin	Indirect	serum_scfa	DM-associated hormones	0.262	0.706	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	Leptin	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+L-Tryptophan+blood-Leptin	Indirect	serum_scfa	DM-associated hormones	0.262	0.706	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	Leptin	2-methyl-butyric acid m-C4+blood-CA+blood+UDCA+blood+Leptin	Indirect	serum_scfa	DM-associated hormones	0.262	0.706	no	no	no	no	no	no	DM-LS
DCA+blood	Leptin	DCA+blood+UDCA+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.706	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Leptin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/20:5-PC+blood+Betaine+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.706	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Leptin	3-(3-Hydroxyphenyl)propanoic acid+stool+UDCA+stool+CDCA+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.706	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Leptin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/20:5-PC+blood-CDCA+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.706	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Leptin	3-(3-Hydroxyphenyl)propanoic acid+stool-20:0/20:5-PC+blood-CDCA+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.706	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Leptin	3-(3-Hydroxyphenyl)propanoic acid+stool-iso-LCA+blood-Sarcosine+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.706	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Leptin	3-(3-Hydroxyphenyl)propanoic acid+stool+UDCA+stool+18:3n6+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.706	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Leptin	3-(3-Hydroxyphenyl)propanoic acid+stool+UDCA+stool-L-Homocystine+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.706	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Leptin	3-(3-Hydroxyphenyl)propanoic acid+stool+UDCA+stool+UDCA+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.706	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Leptin	3-(3-Hydroxyphenyl)propanoic acid+stool-16:0/18:0-PC+blood-UDCA+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.706	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Leptin	3-(3-Hydroxyphenyl)propanoic acid+stool-T-a-MCA+blood-UDCA+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.706	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	Leptin	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2n6c+blood-HCA+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.706	no	no	no	no	no	no	DM-LS
nutriCA+blood	Leptin	nutriCA+blood+UDCA+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.726	0.706	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	Leptin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+L-Methionine+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.706	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	Leptin	Indole-3-Acetic acid+stool+L-Tyrosine+stool+L-Methionine+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.706	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	Leptin	Indole-3-Acetic acid+stool+L-Tryptophan+stool+L-Tryptophan+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.706	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	Leptin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+L-Tryptophan+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.706	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	Leptin	Indole-3-Acetic acid+stool+L-Tyrosine+stool+L-Tryptophan+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.706	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	Leptin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-18:3n6+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.706	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	Leptin	Indole-3-Acetic acid+stool+L-Tryptophan+stool-18:3n6+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.706	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	Leptin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-18:3n6+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.706	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	Leptin	Indole-3-Acetic acid+stool+L-Tyrosine+stool-18:3n6+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.706	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	Leptin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-Sarcosine+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.706	no	no	no	no	no	no	DM-LS
TCA+stool	Leptin	TCA+stool+18:0/18:0-PC+blood-UDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.706	no	no	no	no	no	no	DM-LS
TCA+stool	Leptin	TCA+stool+18:0/18:1-PC+blood-UDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.706	no	no	no	no	no	no	DM-LS
TCA+stool	Leptin	TCA+stool-Ethanolamine+blood+L-Methionine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.706	no	no	no	no	no	no	DM-LS
TCA+stool	Leptin	TCA+stool+18:0/16:0-PC+blood+L-Methionine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.706	no	no	no	no	no	no	DM-LS
TCA+stool	Leptin	TCA+stool-Ethanolamine+blood+L-Tryptophan+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.706	no	no	no	no	no	no	DM-LS
TCA+stool	Leptin	TCA+stool-16:0/20:5-PC+blood+CDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.706	no	no	no	no	no	no	DM-LS
TCA+stool	Leptin	TCA+stool+18:1/18:1-PC+blood-CDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.706	no	no	no	no	no	no	DM-LS
TCA+stool	Leptin	TCA+stool+18:1/18:1-PC+blood+Sarcosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.706	no	no	no	no	no	no	DM-LS
TCA+stool	Leptin	TCA+stool+16:0/20:3-PC+blood+Sarcosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.706	no	no	no	no	no	no	DM-LS
TCA+stool	Leptin	TCA+stool+18:1/18:1-PC+blood-GLCA+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.706	no	no	no	no	no	no	DM-LS
TCA+stool	Leptin	TCA+stool+16:0/20:3-PC+blood-GLCA+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	"HDCA+stool+12,13-EPOME+blood+Hypotaurine+blood-Leptin"	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool-18:1/20:3-PC+blood-CDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool+iso-LCA+stool-CDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool-18:1/18:1-PC+blood-CDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	"HDCA+stool+12,13-EPOME+blood+GLCA+blood-Leptin"	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool-16:0/20:3-PC+blood-GLCA+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool-18:1/18:1-PC+blood-GLCA+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool+LCA+stool+GLCA+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool-20:2/18:0-PC+blood-GLCA+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool-18:0/20:3-PC+blood-GLCA+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool-18:1-LPC+blood+Betaine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool-16:0-LPC+blood+16:0/18:2-PI+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool-nutriCA+stool+HCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool+iso-LCA+stool-18:3n6+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool-nutriCA+stool+UDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool+iso-LCA+stool-UDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool+HDCA+blood-Sarcosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool+iso-LCA+stool-Sarcosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool-16:0/20:3-PC+blood+Sarcosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool-18:1/18:1-PC+blood+Sarcosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool-20:2/18:0-PC+blood+Sarcosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
HDCA+stool	Leptin	HDCA+stool-18:0/20:3-PC+blood+Sarcosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	DM-LS
Lachnospira	Leptin	Lachnospira-d18:1-16:1-SM+blood-L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-LS
Lachnospira	Leptin	Lachnospira-d18:1-16:1-SM+blood-L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-LS
Lachnospira	Leptin	Lachnospira+18:0/20:5-PC+blood+Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-LS
Lachnospira	Leptin	Lachnospira+18:1/18:1-PC+blood-GLCA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-LS
Lachnospira	Leptin	Lachnospira+16:0/20:3-PC+blood-GLCA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-LS
Lachnospira	Leptin	Lachnospira+18:1/18:1-PC+blood-CDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-LS
Lachnospira	Leptin	Lachnospira+18:1/20:3-PC+blood-CDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-LS
Lachnospira	Leptin	Lachnospira+18:0/20:5-PC+blood-CDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-LS
Lachnospira	Leptin	Lachnospira+20:0/20:5-PC+blood-CDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-LS
Lachnospira	Leptin	Lachnospira+18:1/18:1-PC+blood+Sarcosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-LS
Lachnospira	Leptin	Lachnospira+16:0/20:3-PC+blood+Sarcosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	DM-LS
Fusobacterium	Leptin	Fusobacterium+16:0/20:3-PC+blood+Sarcosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.628	0.706	no	no	no	no	no	no	DM-LS
Fusobacterium	Leptin	Fusobacterium+18:1/18:1-PC+blood+Sarcosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.628	0.706	no	no	no	no	no	no	DM-LS
Fusobacterium	Leptin	Fusobacterium+GUDCA+blood+UDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.628	0.706	no	no	no	no	no	no	DM-LS
Fusobacterium	Leptin	Fusobacterium+nutriCA+stool+UDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.628	0.706	no	no	no	no	no	no	DM-LS
Fusobacterium	Leptin	Fusobacterium+18:1/18:1-PC+blood-CDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.628	0.706	no	no	no	no	no	no	DM-LS
Fusobacterium	Leptin	Fusobacterium+nutriCA+stool+HCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.628	0.706	no	no	no	no	no	no	DM-LS
Fusobacterium	Leptin	Fusobacterium+16:0/20:3-PC+blood-GLCA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.628	0.706	no	no	no	no	no	no	DM-LS
Fusobacterium	Leptin	Fusobacterium+18:1/18:1-PC+blood-GLCA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.628	0.706	no	no	no	no	no	no	DM-LS
isobutyric acid C4+blood	Leptin	isobutyric acid C4+blood+isovaleric acid iso-C5+blood-UDCA+blood+Leptin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.706	up	up	no	no	no	no	DM-LS
GCDCA+stool	Leptin	GCDCA+stool+Leptin	Direct	stool_bileacids	DM-associated hormones	0.0471	0.706	no	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Leptin	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+L-Tryptophan+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.706	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Leptin	5-Hydroxytryptamine+stool+L-Tyrosine+stool+L-Tryptophan+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.706	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Leptin	5-Hydroxytryptamine+stool+L-Phenylalanine+stool-18:3n6+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.706	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Leptin	5-Hydroxytryptamine+stool+L-Tyrosine+stool-18:3n6+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.706	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Leptin	5-Hydroxytryptamine+stool-Acetic acid+stool+18:3n6+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.706	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Leptin	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+L-Methionine+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.706	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Leptin	5-Hydroxytryptamine+stool+L-Tyrosine+stool+L-Methionine+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.706	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	Leptin	5-Hydroxytryptamine+stool-Acetic acid+stool+Butyric acid+stool-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.706	dn	dn	no	no	no	no	DM-LS
Odoribacter	Leptin	Odoribacter-T-a-MCA+blood-UDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	DM-LS
Odoribacter	Leptin	Odoribacter-14:0/16:0-PC+blood+16:0/20:4-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	DM-LS
Odoribacter	Leptin	Odoribacter+Ethanolamine+blood+L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	DM-LS
Odoribacter	Leptin	Odoribacter+Ethanolamine+blood+L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	DM-LS
Odoribacter	Leptin	Odoribacter-14:0/16:0-PC+blood+16:0/16:1-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	DM-LS
Odoribacter	Leptin	Odoribacter-14:0/16:0-PC+blood-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	DM-LS
Odoribacter	Leptin	Odoribacter-14:0/16:0-PC+blood-GLCA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	DM-LS
Odoribacter	Leptin	Odoribacter-14:0/16:0-PC+blood+Sarcosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	DM-LS
Odoribacter	Leptin	Odoribacter-14:0/16:0-PC+blood+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	DM-LS
Odoribacter	Leptin	Odoribacter-L-2-Aminobutyric acid+blood+L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Leptin	Isobutyric acid+stool-UDCA+stool+CDCA+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Leptin	Isobutyric acid+stool+L-Tyrosine+stool-18:3n6+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Leptin	Isobutyric acid+stool-UDCA+stool+18:3n6+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Leptin	Isobutyric acid+stool+L-Tryptophan+stool-18:3n6+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Leptin	Isobutyric acid+stool+Phenylacetic acid+stool-18:3n6+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Leptin	Isobutyric acid+stool+L-Phenylalanine+stool-18:3n6+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Leptin	Isobutyric acid+stool-UDCA+stool-L-Homocystine+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Leptin	Isobutyric acid+stool-UDCA+stool+UDCA+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Leptin	Isobutyric acid+stool-nutriCA+stool+UDCA+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Leptin	Isobutyric acid+stool+Phenylacetic acid+stool-Sarcosine+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Leptin	Isobutyric acid+stool+L-Tyrosine+stool+L-Methionine+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Leptin	Isobutyric acid+stool+L-Phenylalanine+stool+L-Methionine+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Leptin	Isobutyric acid+stool-nutriCA+stool+HCA+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Leptin	Isobutyric acid+stool+L-Tyrosine+stool+L-Tryptophan+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Leptin	Isobutyric acid+stool+L-Tryptophan+stool+L-Tryptophan+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	Leptin	Isobutyric acid+stool+L-Phenylalanine+stool+L-Tryptophan+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	DM-LS
Lachnobacterium	Leptin	Lachnobacterium+T-a-MCA+blood-UDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.867	0.706	no	no	no	no	no	no	DM-LS
Kynurenic acid+stool	Leptin	Kynurenic acid+stool-UDCA+stool+CDCA+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.706	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Leptin	Kynurenic acid+stool-UDCA+stool+18:3n6+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.706	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Leptin	Kynurenic acid+stool+L-Tyrosine+stool-18:3n6+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.706	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Leptin	Kynurenic acid+stool+L-Tyrosine+stool+L-Tryptophan+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.706	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Leptin	Kynurenic acid+stool-UDCA+stool-L-Homocystine+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.706	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Leptin	Kynurenic acid+stool+L-Tyrosine+stool+L-Methionine+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.706	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Leptin	Kynurenic acid+stool-UDCA+stool+UDCA+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.706	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Leptin	Kynurenic acid+stool-nutriCA+stool+UDCA+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.706	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	Leptin	Kynurenic acid+stool-nutriCA+stool+HCA+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.706	dn	dn	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-Non-small cell lung cancer+Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-L-Isoleucine+blood+L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-Ethanolamine+blood+L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-L-Isoleucine+blood+L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-Ethanolamine+blood+L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-Hepatitis B+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-Chronic myeloid leukemia+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-B cell receptor signaling pathway+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-TNF signaling pathway+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-Neurotrophin signaling pathway+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-Prostate cancer+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-Hepatitis B+16:0/20:4-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-TNF signaling pathway+16:0/20:4-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-Neurotrophin signaling pathway+16:0/20:4-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-Prostate cancer+16:0/20:4-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-TNF signaling pathway+Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-Neurotrophin signaling pathway+Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
Anaerostipes	Leptin	Anaerostipes-TNF signaling pathway+Sarcosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	DM-LS
TUDCA+stool	Leptin	TUDCA+stool-UDCA+stool+UDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.706	no	no	no	no	no	no	DM-LS
TUDCA+stool	Leptin	TUDCA+stool-UDCA+stool+18:3n6+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.706	no	no	no	no	no	no	DM-LS
TUDCA+stool	Leptin	TUDCA+stool-UDCA+stool-L-Homocystine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.706	no	no	no	no	no	no	DM-LS
TUDCA+stool	Leptin	TUDCA+stool-UDCA+stool+CDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.241	0.706	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool-UDCA+stool+CDCA+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool+Phenylacetic acid+stool-Sarcosine+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool+L-Phenylalanine+stool-18:3n6+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool+Phenylacetic acid+stool-18:3n6+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool-UDCA+stool+18:3n6+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool+L-Tyrosine+stool-18:3n6+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool+L-Tryptophan+stool-18:3n6+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool+L-Phenylalanine+stool+L-Methionine+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool+L-Tyrosine+stool+L-Methionine+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool-UDCA+stool-L-Homocystine+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool+L-Phenylalanine+stool+L-Tryptophan+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool+L-Tyrosine+stool+L-Tryptophan+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool+L-Tryptophan+stool+L-Tryptophan+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool-UDCA+stool+UDCA+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool-nutriCA+stool+UDCA+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	Leptin	Isovaleric acid+stool-nutriCA+stool+HCA+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	DM-LS
Paraprevotella	Leptin	Paraprevotella+Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	DM-LS
iso-LCA+blood	Leptin	iso-LCA+blood-Sarcosine+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.507	0.706	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	Leptin	Phenylacetic acid+stool-Sarcosine+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.706	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	Leptin	Phenylacetic acid+stool-18:3n6+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.706	no	no	no	no	no	no	DM-LS
Gemmiger	Leptin	Gemmiger-18:1-LPC+blood+Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.595	0.706	no	no	no	no	no	no	DM-LS
Gemmiger	Leptin	Gemmiger-GCA+stool+GCDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.595	0.706	no	no	no	no	no	no	DM-LS
GDCA+stool	Leptin	GDCA+stool-L-Histidine+blood+L-Methionine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	DM-LS
GDCA+stool	Leptin	GDCA+stool-L-Isoleucine+blood+L-Methionine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	DM-LS
GDCA+stool	Leptin	GDCA+stool-L-Histidine+blood+L-Tryptophan+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	DM-LS
GDCA+stool	Leptin	GDCA+stool-L-Isoleucine+blood+L-Tryptophan+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	DM-LS
GDCA+stool	Leptin	GDCA+stool+18:0/18:0-PC+blood-UDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	DM-LS
GDCA+stool	Leptin	GDCA+stool+18:0/18:1-PC+blood-UDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	DM-LS
Methanobrevibacter	Leptin	Methanobrevibacter-Sarcosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.629	0.706	no	no	no	no	no	no	DM-LS
Methanobrevibacter	Leptin	Methanobrevibacter+L-Homocystine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.629	0.706	no	no	no	no	no	no	DM-LS
Methanobrevibacter	Leptin	Methanobrevibacter+L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.629	0.706	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	Leptin	L-Tyrosine+stool+L-Methionine+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.706	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	Leptin	L-Tyrosine+stool+L-Tryptophan+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.706	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	Leptin	L-Tyrosine+stool-18:3n6+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.706	no	no	no	no	no	no	DM-LS
CDCA+stool	Leptin	CDCA+stool+HCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.706	no	no	no	no	no	no	DM-LS
CDCA+stool	Leptin	CDCA+stool+18:3n6+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.706	no	no	no	no	no	no	DM-LS
CA+stool	Leptin	CA+stool+CDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.706	no	no	no	no	no	no	DM-LS
CA+stool	Leptin	CA+stool+18:3n6+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia-16:0/22:6-PE+blood-L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia+Primary immunodeficiency-16:0/20:4-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia+DCA+blood+UDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia-Cysteine+blood-HCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia-Cysteine+blood+L-Tryptophan+blood-Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia-Cysteine+blood+L-Methionine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia+Platinum drug resistance-Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia-PPAR signaling pathway+Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia+Platinum drug resistance+L-Homocystine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia+18:1/18:2-PI+blood+L-Homocystine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia+Platinum drug resistance-Sarcosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia+Primary immunodeficiency-Sarcosine+blood+Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia+14:0/18:2-PC+blood+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia+Primary immunodeficiency-16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia+14:0/18:2-PC+blood+16:0/16:1-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia+Primary immunodeficiency-16:0/16:1-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia+14:0/18:2-PC+blood-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
Slackia	Leptin	Slackia+14:0/18:2-PC+blood-GLCA+blood-Leptin	Indirect	Genus	DM-associated hormones	0.94	0.706	no	no	no	no	no	no	DM-LS
HDCA+blood	Leptin	HDCA+blood-Sarcosine+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.706	no	no	no	no	no	no	DM-LS
UDCA+stool	Leptin	UDCA+stool+UDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.706	no	no	no	no	no	no	DM-LS
UDCA+stool	Leptin	UDCA+stool+18:3n6+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.706	no	no	no	no	no	no	DM-LS
UDCA+stool	Leptin	UDCA+stool-L-Homocystine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.706	no	no	no	no	no	no	DM-LS
UDCA+stool	Leptin	UDCA+stool+CDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.706	no	no	no	no	no	no	DM-LS
TDCA+stool	Leptin	TDCA+stool+UDCA+stool+UDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.706	no	no	no	no	no	no	DM-LS
TDCA+stool	Leptin	TDCA+stool+UDCA+stool+18:3n6+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.706	no	no	no	no	no	no	DM-LS
TDCA+stool	Leptin	TDCA+stool+UDCA+stool-L-Homocystine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.706	no	no	no	no	no	no	DM-LS
TDCA+stool	Leptin	TDCA+stool+UDCA+stool+CDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.963	0.706	no	no	no	no	no	no	DM-LS
nutriCA+stool	Leptin	nutriCA+stool+HCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.706	no	no	no	no	no	no	DM-LS
nutriCA+stool	Leptin	nutriCA+stool+UDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.706	no	no	no	no	no	no	DM-LS
GDCA+blood	Leptin	GDCA+blood+iso-LCA+blood-Sarcosine+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.706	no	no	no	no	no	no	DM-LS
acetic acid C2+blood	Leptin	acetic acid C2+blood-Sarcosine+blood+Leptin	Indirect	serum_scfa	DM-associated hormones	0.000193	0.706	up	dn	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	Leptin	isovaleric acid iso-C5+blood-UDCA+blood+Leptin	Indirect	serum_scfa	DM-associated hormones	0.117	0.706	no	no	no	no	no	no	DM-LS
Adlercreutzia	Leptin	Adlercreutzia+18:0-LPC+blood+L-Homocystine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.548	0.706	no	no	no	no	no	no	DM-LS
Adlercreutzia	Leptin	Adlercreutzia+18:0-LPC+blood+L-Citrulline+blood-Leptin	Indirect	Genus	DM-associated hormones	0.548	0.706	no	no	no	no	no	no	DM-LS
Adlercreutzia	Leptin	Adlercreutzia-14:0+blood-Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.548	0.706	no	no	no	no	no	no	DM-LS
Adlercreutzia	Leptin	Adlercreutzia+18:0-LPC+blood+Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.548	0.706	no	no	no	no	no	no	DM-LS
Adlercreutzia	Leptin	Adlercreutzia+18:1-LPC+blood+Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.548	0.706	no	no	no	no	no	no	DM-LS
Adlercreutzia	Leptin	Adlercreutzia-16:0/20:5-PC+blood+CDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.548	0.706	no	no	no	no	no	no	DM-LS
Adlercreutzia	Leptin	Adlercreutzia-14:0+blood+16:0/18:2-PI+blood+Leptin	Indirect	Genus	DM-associated hormones	0.548	0.706	no	no	no	no	no	no	DM-LS
Adlercreutzia	Leptin	Adlercreutzia-14:0+blood+16:0/16:1-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.548	0.706	no	no	no	no	no	no	DM-LS
Adlercreutzia	Leptin	Adlercreutzia+16:0/18:0-PC+blood-UDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.548	0.706	no	no	no	no	no	no	DM-LS
Clostridium	Leptin	Clostridium+CDCA+blood+Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-LS
Clostridium	Leptin	Clostridium-Butyric acid+stool-Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-LS
 Clostridium	Leptin	Clostridium+Butyric acid+stool-Leptin	Indirect	Genus	DM-associated hormones	NA	0.706	NA	NA	NA	no	no	no	DM-LS
Clostridium	Leptin	Clostridium-Butyric acid+stool-Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	DM-LS
 Clostridium	Leptin	Clostridium+Butyric acid+stool-Leptin	Indirect	Genus	DM-associated hormones	NA	0.706	NA	NA	NA	no	no	no	DM-LS
T-¦Á-MCA+stool	Leptin	T-¦Á-MCA+stool-TCA+stool+18:0/18:0-PC+blood-UDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.706	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Leptin	T-¦Á-MCA+stool-TCA+stool+18:0/18:1-PC+blood-UDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.706	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Leptin	T-¦Á-MCA+stool-TCA+stool-Ethanolamine+blood+L-Methionine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.706	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Leptin	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+L-Methionine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.706	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Leptin	T-¦Á-MCA+stool-TCA+stool-Ethanolamine+blood+L-Tryptophan+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.706	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Leptin	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+CDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.706	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Leptin	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood-CDCA+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.706	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Leptin	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+Sarcosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.706	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Leptin	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+Sarcosine+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.706	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Leptin	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood-GLCA+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.706	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	Leptin	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood-GLCA+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.48	0.706	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	Leptin	12-ketoDCA+blood+GLCA+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.706	no	no	no	no	no	no	DM-LS
Butyricicoccus	Leptin	Butyricicoccus+Butyric acid+stool-Leptin	Indirect	Genus	DM-associated hormones	0.852	0.706	no	no	no	no	no	no	DM-LS
Blautia	IP-10	Blautia-L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	DM-LS
Parabacteroides	IP-10	Parabacteroides+Valine+blood-IP-10	Indirect	Genus	serum_cytokines	4.19E-05	0.394	no	up	up	no	no	no	DM-LS
Parabacteroides	IP-10	Parabacteroides-Glucagon signaling pathway+IP-10	Indirect	Genus	serum_cytokines	4.19E-05	0.394	no	up	up	no	no	no	DM-LS
Parabacteroides	IP-10	Parabacteroides-Thyroid cancer+IP-10	Indirect	Genus	serum_cytokines	4.19E-05	0.394	no	up	up	no	no	no	DM-LS
Dorea	IP-10	Dorea-18:0/22:6-PE+blood-18:1-LPC+blood-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	DM-LS
Dorea	IP-10	Dorea-Lipid and atherosclerosis-14:0/18:2-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	DM-LS
Dorea	IP-10	Dorea-18:0/22:6-PE+blood-L-2-Aminobutyric acid+blood-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	DM-LS
Dorea	IP-10	Dorea-Lipid and atherosclerosis+16:0/22:6-PE+blood+IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	DM-LS
Faecalibacterium	IP-10	Faecalibacterium-Phenylacetic acid+stool-Sarcosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	IP-10	Faecalibacterium-Phenylacetic acid+stool-18:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	IP-10	Faecalibacterium-L-Tryptophan+stool-18:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	IP-10	Faecalibacterium-16:0/18:2-PC+blood+18:0/20:5-PC+blood-IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	IP-10	Faecalibacterium-Cysteine+blood+L-2-Aminobutyric acid+blood-IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	IP-10	Faecalibacterium-Cysteine+blood+Valine+blood-IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	IP-10	Faecalibacterium-L-Tryptophan+stool+L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	IP-10	Faecalibacterium-L-Tryptophan+stool+L-Tryptophan+blood-IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	IP-10	Faecalibacterium-Cysteine+blood+L-Tryptophan+blood-IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	IP-10	Faecalibacterium-16:0/18:2-PC+blood+L-Glutamine+blood-IP-10	Indirect	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	DM-LS
TUDCA+blood	IP-10	TUDCA+blood+Eotaxin-IL-6-IP-10	Indirect	serum_bileacids	serum_cytokines	0.0282	0.394	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	IP-10	isocapric acid iso-C6+blood-n3+blood-Eotaxin-IL-6-IP-10	Indirect	serum_scfa	serum_cytokines	0.0458	0.394	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	IP-10	isocapric acid iso-C6+blood-n3+blood+Taurine+blood+Valine+blood-IP-10	Indirect	serum_scfa	serum_cytokines	0.0458	0.394	no	no	dn	no	no	no	DM-LS
Bacteroides	IP-10	Bacteroides+3-(3-Hydroxyphenyl)propanoic acid+stool+IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool+16:0/18:0-PS+blood+16:0/22:6-PE+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool+16:0/18:0-PS+blood-18:1-LPC+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool+18:0/18:0-PS+blood-18:1-LPC+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool-18:0/18:0-PC+blood+18:1-LPC+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool+18:0/22:6-PE+blood-18:1-LPC+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool-18:0/18:1-PC+blood+18:1-LPC+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool+16:0/18:0-PS+blood-18:0/20:5-PC+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool-18:0/18:2-PC+blood+18:0/20:5-PC+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool+18:0/18:0-PS+blood-18:0/20:5-PC+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool-18:0/18:2-PC+blood+18:1/20:4-PC+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool+16:0/18:0-PS+blood-L-Ornithine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool-18:0/18:0-PC+blood+L-2-Aminobutyric acid+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool+18:0/22:6-PE+blood-L-2-Aminobutyric acid+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool-18:0/18:1-PC+blood+L-2-Aminobutyric acid+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool-18:1/18:0-PC+blood+L-Glutamine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool-18:0/18:2-PC+blood+L-Glutamine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool-Glycine+blood+L-Glutamine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool+18:0/18:1-PE+blood-L-Glutamine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool-24:1+blood+L-Glutamine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IP-10	Propionic acid+stool-20:3/18:0-PC+blood+L-Glutamine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	DM-LS
[Ruminococcus]	IP-10	[Ruminococcus]+16:0/20:4-PI+blood+IP-10	Indirect	Genus	serum_cytokines	0.0679	0.394	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	IP-10	[Ruminococcus]+16:0/18:2-PI+blood+IP-10	Indirect	Genus	serum_cytokines	0.0679	0.394	no	no	dn	no	no	no	DM-LS
GUDCA+blood	IP-10	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-IL-6-IP-10	Indirect	serum_bileacids	serum_cytokines	0.0766	0.394	no	no	dn	no	no	no	DM-LS
Acetic acid+stool	IP-10	Acetic acid+stool+AA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0656	0.394	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	IP-10	Acetic acid+stool+18:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.0656	0.394	dn	no	no	no	no	no	DM-LS
Alistipes	IP-10	Alistipes-L-Arginine+blood+Valine+blood-IP-10	Indirect	Genus	serum_cytokines	0.0114	0.394	no	up	no	no	no	no	DM-LS
Alistipes	IP-10	Alistipes-L-Aspartic acid+blood+L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	0.0114	0.394	no	up	no	no	no	no	DM-LS
Alistipes	IP-10	Alistipes+12-ketoDCA+stool+16:0/22:6-PE+blood+IP-10	Indirect	Genus	serum_cytokines	0.0114	0.394	no	up	no	no	no	no	DM-LS
Alistipes	IP-10	Alistipes-L-Arginine+blood+L-Glutamine+blood-IP-10	Indirect	Genus	serum_cytokines	0.0114	0.394	no	up	no	no	no	no	DM-LS
Alistipes	IP-10	Alistipes-L-Arginine+blood+L-Citrulline+blood-IP-10	Indirect	Genus	serum_cytokines	0.0114	0.394	no	up	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas-Cardiac muscle contraction+Melanogenesis+IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas-Prion disease-18:0/20:5-PC+blood-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas-Cardiac muscle contraction-18:0/20:5-PC+blood-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas-14:0/20:4-PC+blood+16:0/18:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas+L-Lysine+blood+Valine+blood-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas+L-Histidine+blood+Valine+blood-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas+L-Lysine+blood+L-Tryptophan+blood-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas+L-Histidine+blood+L-Tryptophan+blood-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas-Prion disease-L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas-Cardiac muscle contraction-L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas+L-Lysine+blood+L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas-14:0/20:4-PC+blood-L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas+L-Histidine+blood+L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas-d18:1-14:0-SM+blood-L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas-14:0/20:4-PC+blood+18:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas-Cardiac muscle contraction+Aldosterone synthesis and secretion+IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas-Prion disease+Bacterial invasion of epithelial cells-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas-14:0/20:4-PC+blood-L-Glutamine+blood-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas+20:5/18:0-PC+blood+L-Glutamine+blood-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas-d18:1-14:0-SM+blood-L-Glutamine+blood-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Butyricimonas	IP-10	Butyricimonas-Cardiac muscle contraction-Fc gamma R-mediated phagocytosis-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	"Collinsella-9,10-EPOME+blood+L-Citrulline+blood-IP-10"	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Spinocerebellar ataxia+L-Citrulline+blood-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Phosphatidylinositol signaling system+L-Citrulline+blood-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-RNA degradation-Tight junction-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-NF-kappa B signaling pathway-Tight junction-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella+Arachidonic acid metabolism+Tight junction-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-ErbB signaling pathway-Tight junction-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Phosphatidylinositol signaling system-Tight junction-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Central carbon metabolism in cancer+18:0/20:5-PC+blood-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Insulin resistance-Bacterial invasion of epithelial cells-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-NF-kappa B signaling pathway-Bacterial invasion of epithelial cells-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-T cell receptor signaling pathway+Pathways in cancer+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Signaling pathways regulating pluripotency of stem cells+Pathways in cancer+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Hepatitis B+Pathways in cancer+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Insulin resistance+Pathways in cancer+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-NF-kappa B signaling pathway+Pathways in cancer+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella+Arachidonic acid metabolism-Pathways in cancer+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Prolactin signaling pathway+Pathways in cancer+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-AGE-RAGE signaling pathway in diabetic complications+Pathways in cancer+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-ErbB signaling pathway+Pathways in cancer+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Phosphatidylinositol signaling system+Pathways in cancer+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-DHA+blood-L-2-Aminobutyric acid+blood-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Hepatitis B+16:0/18:2-PI+blood+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Prostate cancer+16:0/18:2-PI+blood+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-NF-kappa B signaling pathway+16:0/18:2-PI+blood+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Neurotrophin signaling pathway+16:0/18:2-PI+blood+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella+Parkinson disease+16:0/18:2-PI+blood+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella+Arachidonic acid metabolism+Biosynthesis of amino acids-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella+Parkinson disease+14:0/16:0-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Wnt signaling pathway-Systemic lupus erythematosus-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Signaling pathways regulating pluripotency of stem cells-Systemic lupus erythematosus-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-RNA degradation-Systemic lupus erythematosus-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Spinocerebellar ataxia-Systemic lupus erythematosus-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Choline metabolism in cancer-Systemic lupus erythematosus-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Insulin resistance-Systemic lupus erythematosus-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Gastric cancer-Systemic lupus erythematosus-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Phosphatidylinositol signaling system-Systemic lupus erythematosus-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella+Parkinson disease-AA+blood-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Hepatitis B+Small cell lung cancer+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Insulin resistance+Small cell lung cancer+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Prostate cancer+Small cell lung cancer+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-NF-kappa B signaling pathway+Small cell lung cancer+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Neurotrophin signaling pathway+Small cell lung cancer+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Prolactin signaling pathway+Small cell lung cancer+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Wnt signaling pathway-Rheumatoid arthritis-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Insulin resistance-Rheumatoid arthritis-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Prostate cancer-Rheumatoid arthritis-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Phosphatidylinositol signaling system-Rheumatoid arthritis-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-RNA degradation-Neuroactive ligand-receptor interaction-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Phosphatidylinositol signaling system-Neuroactive ligand-receptor interaction-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-RNA degradation-Lysosome-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Phosphatidylinositol signaling system-Lysosome-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-RNA degradation-Peroxisome-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Phosphatidylinositol signaling system-Peroxisome-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-RNA degradation+p53 signaling pathway+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Phosphatidylinositol signaling system+p53 signaling pathway+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Wnt signaling pathway-Fc gamma R-mediated phagocytosis-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Signaling pathways regulating pluripotency of stem cells-Fc gamma R-mediated phagocytosis-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-RNA degradation-Fc gamma R-mediated phagocytosis-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Phosphatidylinositol signaling system-Fc gamma R-mediated phagocytosis-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Wnt signaling pathway+Glucagon signaling pathway+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-T cell receptor signaling pathway+Glucagon signaling pathway+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Signaling pathways regulating pluripotency of stem cells+Glucagon signaling pathway+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-RNA degradation+Glucagon signaling pathway+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Long-term potentiation+Glucagon signaling pathway+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Phosphatidylinositol signaling system+Glucagon signaling pathway+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Wnt signaling pathway-Leukocyte transendothelial migration-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Signaling pathways regulating pluripotency of stem cells-Leukocyte transendothelial migration-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-RNA degradation-Leukocyte transendothelial migration-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Phosphatidylinositol signaling system-Leukocyte transendothelial migration-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Wnt signaling pathway-Neutrophil extracellular trap formation-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Signaling pathways regulating pluripotency of stem cells-Neutrophil extracellular trap formation-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-RNA degradation-Neutrophil extracellular trap formation-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Phosphatidylinositol signaling system-Neutrophil extracellular trap formation-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-HDCA+stool-18:1-LPC+blood-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Hepatitis B+16:0/20:4-PI+blood+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Prostate cancer+16:0/20:4-PI+blood+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Neurotrophin signaling pathway+16:0/20:4-PI+blood+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Wnt signaling pathway-Tuberculosis-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Signaling pathways regulating pluripotency of stem cells-Tuberculosis-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-RNA degradation-Tuberculosis-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Insulin resistance-Tuberculosis-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella+Parkinson disease-Tuberculosis-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Phosphatidylinositol signaling system-Tuberculosis-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Wnt signaling pathway-Staphylococcus aureus infection-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Signaling pathways regulating pluripotency of stem cells-Staphylococcus aureus infection-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-RNA degradation-Staphylococcus aureus infection-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Spinocerebellar ataxia-Staphylococcus aureus infection-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Long-term potentiation-Staphylococcus aureus infection-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Insulin resistance-Staphylococcus aureus infection-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Phosphatidylinositol signaling system-Staphylococcus aureus infection-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Wnt signaling pathway-Salmonella infection-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-RNA degradation-Salmonella infection-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Insulin resistance-Salmonella infection-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Phosphatidylinositol signaling system-Salmonella infection-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Long-term potentiation+Dopaminergic synapse+IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Wnt signaling pathway-Pathogenic Escherichia coli infection-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Signaling pathways regulating pluripotency of stem cells-Pathogenic Escherichia coli infection-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-RNA degradation-Pathogenic Escherichia coli infection-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Spinocerebellar ataxia-Pathogenic Escherichia coli infection-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Insulin resistance-Pathogenic Escherichia coli infection-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Phosphatidylinositol signaling system-Pathogenic Escherichia coli infection-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
Collinsella	IP-10	Collinsella-Long-term potentiation-Betaine+blood-IP-10	Indirect	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	IP-10	total_blood_scfa+blood+TUDCA+blood+Eotaxin-IL-6-IP-10	Indirect	serum_scfa	serum_cytokines	0.168	0.394	no	no	no	no	no	no	DM-LS
[Eubacterium]	IP-10	[Eubacterium]-Pathogenic Escherichia coli infection-IP-10	Indirect	Genus	serum_cytokines	0.0692	0.394	no	no	no	no	no	no	DM-LS
[Eubacterium]	IP-10	[Eubacterium]+p53 signaling pathway+IP-10	Indirect	Genus	serum_cytokines	0.0692	0.394	no	no	no	no	no	no	DM-LS
[Eubacterium]	IP-10	[Eubacterium]-Salmonella infection-IP-10	Indirect	Genus	serum_cytokines	0.0692	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool+20:4/18:0-PE+blood-L-Ornithine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool+18:1/18:1-PE+blood-L-Ornithine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool+iso-LCA+blood+L-Ornithine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool-UDCA+stool-L-Ornithine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool+20:4/18:0-PE+blood-Valine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool-SFA%+blood+Valine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool+18:1/18:1-PE+blood-Betaine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool-Cystine+blood+L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool+18:0/18:1-PE+blood-L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool-24:1+blood+L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool-Glycine+blood+L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool-20:3/18:0-PC+blood+L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool+18:1/18:1-PE+blood-L-Citrulline+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool-Cystine+blood+L-2-Aminobutyric acid+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool+iso-LCA+blood-Sarcosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool+GLCA+blood-Sarcosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool-UDCA+stool-18:0/20:5-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
LCA+stool	IP-10	LCA+stool-UDCA+stool+18:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+18:0/22:6-PE+blood-18:1-LPC+blood-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+Apoptosis+Betaine+blood-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+Apoptosis+Bacterial invasion of epithelial cells-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+18:0/22:6-PE+blood-L-2-Aminobutyric acid+blood-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia-Retrograde endocannabinoid signaling-L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+Apoptosis-Glucagon signaling pathway+IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+Apoptosis+Fc gamma R-mediated phagocytosis-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+Apoptosis-Inflammatory mediator regulation of TRP channels+IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+Apoptosis+Neutrophil extracellular trap formation-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+Apoptosis-Melanogenesis+IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+Apoptosis+Leukocyte transendothelial migration-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+Apoptosis+Pathogenic Escherichia coli infection-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+Apoptosis+Systemic lupus erythematosus-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+Apoptosis+Rheumatoid arthritis-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia-L-Alanine+blood+Sarcosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+Apoptosis+Salmonella infection-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+Apoptosis+Staphylococcus aureus infection-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+12-ketoDCA+stool+16:0/22:6-PE+blood+IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+Apoptosis+Tuberculosis-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia-Retrograde endocannabinoid signaling-18:0/20:5-PC+blood-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+Apoptosis+Tight junction-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Akkermansia	IP-10	Akkermansia+Apoptosis-Aldosterone synthesis and secretion+IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	DM-LS
Bifidobacterium	IP-10	Bifidobacterium+Chemical carcinogenesis - receptor activation+Small cell lung cancer+IP-10	Indirect	Genus	serum_cytokines	0.105	0.394	no	dn	no	no	no	no	DM-LS
Bifidobacterium	IP-10	Bifidobacterium+Glycine+blood+L-Glutamine+blood-IP-10	Indirect	Genus	serum_cytokines	0.105	0.394	no	dn	no	no	no	no	DM-LS
Bifidobacterium	IP-10	Bifidobacterium+Chemical carcinogenesis - receptor activation-L-Glutamine+blood-IP-10	Indirect	Genus	serum_cytokines	0.105	0.394	no	dn	no	no	no	no	DM-LS
Bifidobacterium	IP-10	Bifidobacterium+d18:1-18:1-SM+blood-L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	0.105	0.394	no	dn	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Cell adhesion molecules-Valine+blood-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Type I diabetes mellitus-L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Allograft rejection-L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Graft-versus-host disease-L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Cell adhesion molecules-L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Autoimmune thyroid disease-L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Type I diabetes mellitus+Rheumatoid arthritis-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Phagosome+Rheumatoid arthritis-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Cell adhesion molecules+Rheumatoid arthritis-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Autoimmune thyroid disease+Rheumatoid arthritis-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Type I diabetes mellitus-L-Citrulline+blood-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Allograft rejection-L-Citrulline+blood-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Graft-versus-host disease-L-Citrulline+blood-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Phagosome-L-Citrulline+blood-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Cell adhesion molecules-L-Citrulline+blood-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Autoimmune thyroid disease-L-Citrulline+blood-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Type I diabetes mellitus+Sarcosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Allograft rejection+Sarcosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus-L-Homocystine+blood-Sarcosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Graft-versus-host disease+Sarcosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Autoimmune thyroid disease+Sarcosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Type I diabetes mellitus-Pathways in cancer+IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Phagosome-Pathways in cancer+IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Cell adhesion molecules-Pathways in cancer+IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Type I diabetes mellitus+Pathogenic Escherichia coli infection-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Natural killer cell mediated cytotoxicity+Pathogenic Escherichia coli infection-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Endocytosis+Pathogenic Escherichia coli infection-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Phagosome+Pathogenic Escherichia coli infection-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Cell adhesion molecules+Pathogenic Escherichia coli infection-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Phagosome+Bacterial invasion of epithelial cells-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Phagosome+Fc gamma R-mediated phagocytosis-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Type I diabetes mellitus+16:0/22:6-PE+blood+IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Natural killer cell mediated cytotoxicity+16:0/22:6-PE+blood+IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Endocytosis+16:0/22:6-PE+blood+IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Allograft rejection+16:0/22:6-PE+blood+IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Graft-versus-host disease+16:0/22:6-PE+blood+IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Phagosome+16:0/22:6-PE+blood+IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Cell adhesion molecules+16:0/22:6-PE+blood+IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Autoimmune thyroid disease+16:0/22:6-PE+blood+IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Phagosome-Glucagon signaling pathway+IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Phagosome+Leukocyte transendothelial migration-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Cell adhesion molecules+Leukocyte transendothelial migration-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Phagosome+Neutrophil extracellular trap formation-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Cell adhesion molecules+Neutrophil extracellular trap formation-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Cell adhesion molecules-L-2-Aminobutyric acid+blood-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Phagosome+Staphylococcus aureus infection-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Cell adhesion molecules+Staphylococcus aureus infection-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Phagosome+Salmonella infection-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Cell adhesion molecules+Salmonella infection-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Phagosome+Systemic lupus erythematosus-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Cell adhesion molecules+Systemic lupus erythematosus-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Phagosome+Tuberculosis-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Cell adhesion molecules+Tuberculosis-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
Ruminococcus	IP-10	Ruminococcus+Phagosome+Tight junction-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	DM-LS
GCDCA+blood	IP-10	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin-IL-6-IP-10	Indirect	serum_bileacids	serum_cytokines	0.31	0.394	no	no	no	no	no	no	DM-LS
Succinivibrio	IP-10	Succinivibrio-L-Tyrosine+stool+L-Tryptophan+blood-IP-10	Indirect	Genus	serum_cytokines	0.138	0.394	no	no	no	no	no	no	DM-LS
Succinivibrio	IP-10	Succinivibrio-L-Phenylalanine+stool+L-Tryptophan+blood-IP-10	Indirect	Genus	serum_cytokines	0.138	0.394	no	no	no	no	no	no	DM-LS
Succinivibrio	IP-10	Succinivibrio-L-Tyrosine+stool+L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	0.138	0.394	no	no	no	no	no	no	DM-LS
Succinivibrio	IP-10	Succinivibrio-L-Phenylalanine+stool+L-Ornithine+blood-IP-10	Indirect	Genus	serum_cytokines	0.138	0.394	no	no	no	no	no	no	DM-LS
Succinivibrio	IP-10	Succinivibrio-L-Tyrosine+stool-16:0/22:6-PE+blood+IP-10	Indirect	Genus	serum_cytokines	0.138	0.394	no	no	no	no	no	no	DM-LS
Succinivibrio	IP-10	Succinivibrio-Phospholipase D signaling pathway+AA+blood-IP-10	Indirect	Genus	serum_cytokines	0.138	0.394	no	no	no	no	no	no	DM-LS
Succinivibrio	IP-10	Succinivibrio-L-Tyrosine+stool-18:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.138	0.394	no	no	no	no	no	no	DM-LS
Succinivibrio	IP-10	Succinivibrio-L-Phenylalanine+stool-18:3n6+blood+IP-10	Indirect	Genus	serum_cytokines	0.138	0.394	no	no	no	no	no	no	DM-LS
ACA+blood	IP-10	ACA+blood-Eotaxin-IL-6-IP-10	Indirect	serum_bileacids	serum_cytokines	0.338	0.394	no	no	no	no	no	no	DM-LS
ACA+blood	IP-10	ACA+blood+Glycine+blood+L-Glutamine+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.338	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool-SFA%+blood+Valine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool+16:0/18:0-PS+blood+16:0/22:6-PE+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool-18:0/18:2-PC+blood+18:1/20:4-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool+18:1/18:1-PE+blood-L-Citrulline+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool+iso-LCA+stool-Sarcosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool-16:0/20:3-PC+blood+Sarcosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool-18:1/18:1-PC+blood+Sarcosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool+18:1/18:1-PE+blood-L-Ornithine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool+16:0/18:0-PS+blood-L-Ornithine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool-GCA+stool+16:0/18:3-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool-GCA+stool+L-2-Aminobutyric acid+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool-Cystine+blood+L-2-Aminobutyric acid+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool+18:0/18:0-PS+blood-18:0/20:5-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool+16:0/18:0-PS+blood-18:0/20:5-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool-18:0/18:2-PC+blood+18:0/20:5-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool+18:0/18:0-PS+blood-18:1-LPC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool+HDCA+stool-18:1-LPC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool+16:0/18:0-PS+blood-18:1-LPC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool+iso-LCA+stool-18:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool-Cystine+blood+L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool-18:1/18:0-PC+blood+L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool-Glycine+blood+L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool-18:0/18:2-PC+blood+L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool+18:0/18:1-PE+blood-L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool-24:1+blood+L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool-20:3/18:0-PC+blood+L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
DCA+stool	IP-10	DCA+stool+18:1/18:1-PE+blood-Betaine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	DM-LS
Butyric acid+stool	IP-10	Butyric acid+stool+AA+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	IP-10	4-hydroxybenzoic acid+stool+L-Asparagine+blood+L-Glutamine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.394	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	IP-10	4-hydroxybenzoic acid+stool-HDCA+stool-18:1-LPC+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.394	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	IP-10	4-hydroxybenzoic acid+stool-Phenylacetic acid+stool-Sarcosine+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.394	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	IP-10	4-hydroxybenzoic acid+stool-HDCA+blood-Sarcosine+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.394	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	IP-10	4-hydroxybenzoic acid+stool+L-Asparagine+blood+L-Citrulline+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.394	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	IP-10	4-hydroxybenzoic acid+stool+SFA%+blood+Valine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.394	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	IP-10	4-hydroxybenzoic acid+stool+L-Asparagine+blood+L-Tryptophan+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.394	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	IP-10	4-hydroxybenzoic acid+stool-HDCA+blood+L-Ornithine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.394	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	IP-10	4-hydroxybenzoic acid+stool+CDCA+stool-L-Ornithine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.394	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	IP-10	4-hydroxybenzoic acid+stool-Phenylacetic acid+stool-18:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.394	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	IP-10	4-hydroxybenzoic acid+stool+CDCA+stool+18:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.394	no	dn	no	no	no	no	DM-LS
GCA+blood	IP-10	GCA+blood+GDCA+blood+iso-LCA+blood+L-Ornithine+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.16	0.394	no	no	no	no	no	no	DM-LS
GCA+blood	IP-10	GCA+blood+GDCA+blood+iso-LCA+blood-Sarcosine+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.16	0.394	no	no	no	no	no	no	DM-LS
ACA+stool	IP-10	ACA+stool+Sarcosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.417	0.394	no	no	no	no	no	no	DM-LS
ACA+stool	IP-10	ACA+stool-L-Citrulline+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.417	0.394	no	no	no	no	no	no	DM-LS
CDCA+blood	IP-10	CDCA+blood-L-Tryptophan+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.506	0.394	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IP-10	capric acid C6+blood-Sarcosine+blood+IP-10	Indirect	serum_scfa	serum_cytokines	0.433	0.394	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IP-10	capric acid C6+blood+L-Glutamine+blood-IP-10	Indirect	serum_scfa	serum_cytokines	0.433	0.394	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IP-10	capric acid C6+blood+L-Tryptophan+blood-IP-10	Indirect	serum_scfa	serum_cytokines	0.433	0.394	no	no	no	no	no	no	DM-LS
Pyramidobacter	IP-10	Pyramidobacter-Carbon metabolism-IP-10	Indirect	Genus	serum_cytokines	0.45	0.394	no	no	no	no	no	no	DM-LS
Pyramidobacter	IP-10	Pyramidobacter-Lysosome-IP-10	Indirect	Genus	serum_cytokines	0.45	0.394	no	no	no	no	no	no	DM-LS
Pyramidobacter	IP-10	Pyramidobacter+Glucagon signaling pathway+IP-10	Indirect	Genus	serum_cytokines	0.45	0.394	no	no	no	no	no	no	DM-LS
Pyramidobacter	IP-10	Pyramidobacter+Small cell lung cancer+IP-10	Indirect	Genus	serum_cytokines	0.45	0.394	no	no	no	no	no	no	DM-LS
Pyramidobacter	IP-10	Pyramidobacter+Pathways in cancer+IP-10	Indirect	Genus	serum_cytokines	0.45	0.394	no	no	no	no	no	no	DM-LS
Prevotella	IP-10	Prevotella-Glycolysis / Gluconeogenesis-IP-10	Indirect	Genus	serum_cytokines	0.287	0.394	no	no	no	no	no	no	DM-LS
Prevotella	IP-10	Prevotella+Aldosterone synthesis and secretion+IP-10	Indirect	Genus	serum_cytokines	0.287	0.394	no	no	no	no	no	no	DM-LS
Prevotella	IP-10	Prevotella+GnRH signaling pathway+IP-10	Indirect	Genus	serum_cytokines	0.287	0.394	no	no	no	no	no	no	DM-LS
Prevotella	IP-10	Prevotella+Inflammatory mediator regulation of TRP channels+IP-10	Indirect	Genus	serum_cytokines	0.287	0.394	no	no	no	no	no	no	DM-LS
Prevotella	IP-10	Prevotella-Carbon metabolism-IP-10	Indirect	Genus	serum_cytokines	0.287	0.394	no	no	no	no	no	no	DM-LS
Prevotella	IP-10	Prevotella+Amphetamine addiction+IP-10	Indirect	Genus	serum_cytokines	0.287	0.394	no	no	no	no	no	no	DM-LS
Prevotella	IP-10	Prevotella+Dopaminergic synapse+IP-10	Indirect	Genus	serum_cytokines	0.287	0.394	no	no	no	no	no	no	DM-LS
Prevotella	IP-10	Prevotella+Melanogenesis+IP-10	Indirect	Genus	serum_cytokines	0.287	0.394	no	no	no	no	no	no	DM-LS
TCA+blood	IP-10	TCA+blood+TUDCA+blood+Eotaxin-IL-6-IP-10	Indirect	serum_bileacids	serum_cytokines	0.339	0.394	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IP-10	iso-DCA+blood+Valine+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.38	0.394	no	no	no	no	no	no	DM-LS
HCA+stool	IP-10	HCA+stool-18:0/20:5-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.155	0.394	no	no	no	no	no	no	DM-LS
Roseburia	IP-10	Roseburia-Valine+blood-IP-10	Indirect	Genus	serum_cytokines	0.495	0.394	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	IP-10	12-ketoDCA+stool+16:0/22:6-PE+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.505	0.394	no	no	no	no	no	no	DM-LS
GLCA+blood	IP-10	GLCA+blood-Sarcosine+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.319	0.394	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	IP-10	L-Tryptophan+stool+L-Tryptophan+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.557	0.394	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	IP-10	L-Tryptophan+stool+L-Ornithine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.557	0.394	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	IP-10	L-Tryptophan+stool-18:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.557	0.394	no	no	no	no	no	no	DM-LS
CA+blood	IP-10	CA+blood-L-Glutamine+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.606	0.394	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IP-10	L-Phenylalanine+stool+L-Tryptophan+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.398	0.394	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IP-10	L-Phenylalanine+stool-18:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.398	0.394	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IP-10	L-Phenylalanine+stool+L-Ornithine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.398	0.394	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	IP-10	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood+SFA%+blood+Valine+blood-IP-10	Indirect	serum_scfa	serum_cytokines	0.407	0.394	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	IP-10	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin-IL-6-IP-10	Indirect	serum_scfa	serum_cytokines	0.407	0.394	no	no	no	no	no	no	DM-LS
GCA+stool	IP-10	GCA+stool+L-2-Aminobutyric acid+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0809	0.394	no	no	no	no	no	no	DM-LS
GCA+stool	IP-10	GCA+stool+16:0/18:3-PC+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.0809	0.394	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	IP-10	T-a-MCA+blood+UFA%+blood-Eotaxin-IL-6-IP-10	Indirect	serum_bileacids	serum_cytokines	0.478	0.394	no	no	no	no	no	no	DM-LS
Coprococcus	IP-10	Coprococcus-Melanogenesis+IP-10	Indirect	Genus	serum_cytokines	0.612	0.394	no	no	no	no	no	no	DM-LS
Coprococcus	IP-10	Coprococcus-16:0/18:3-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.612	0.394	no	no	no	no	no	no	DM-LS
Coprococcus	IP-10	Coprococcus-Amphetamine addiction+IP-10	Indirect	Genus	serum_cytokines	0.612	0.394	no	no	no	no	no	no	DM-LS
Coprococcus	IP-10	Coprococcus-Aldosterone synthesis and secretion+IP-10	Indirect	Genus	serum_cytokines	0.612	0.394	no	no	no	no	no	no	DM-LS
Coprococcus	IP-10	Coprococcus+Peroxisome-IP-10	Indirect	Genus	serum_cytokines	0.612	0.394	no	no	no	no	no	no	DM-LS
Coprococcus	IP-10	Coprococcus-Dopaminergic synapse+IP-10	Indirect	Genus	serum_cytokines	0.612	0.394	no	no	no	no	no	no	DM-LS
Coprococcus	IP-10	Coprococcus+Biosynthesis of amino acids-IP-10	Indirect	Genus	serum_cytokines	0.612	0.394	no	no	no	no	no	no	DM-LS
Coprococcus	IP-10	Coprococcus+Salmonella infection-IP-10	Indirect	Genus	serum_cytokines	0.612	0.394	no	no	no	no	no	no	DM-LS
Coprococcus	IP-10	Coprococcus+Betaine+blood-IP-10	Indirect	Genus	serum_cytokines	0.612	0.394	no	no	no	no	no	no	DM-LS
Oscillospira	IP-10	Oscillospira+Valine+blood-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-LS
Oscillospira	IP-10	Oscillospira+Peroxisome-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	DM-LS
HCA+blood	IP-10	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin-IL-6-IP-10	Indirect	serum_bileacids	serum_cytokines	0.544	0.394	no	no	no	no	no	no	DM-LS
HCA+blood	IP-10	HCA+blood-MUFA+blood-PUFA/MUFA+blood+TXB2+blood+Valine+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.544	0.394	no	no	no	no	no	no	DM-LS
HCA+blood	IP-10	HCA+blood-MUFA+blood-PUFA/MUFA+blood+SFA%+blood+Valine+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.544	0.394	no	no	no	no	no	no	DM-LS
HCA+blood	IP-10	HCA+blood-MUFA+blood+MUFA%+blood+SFA%+blood+Valine+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.544	0.394	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IP-10	iso-LCA+stool-18:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.72	0.394	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IP-10	iso-LCA+stool-Sarcosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.72	0.394	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	IP-10	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+L-Ornithine+blood-IP-10	Indirect	serum_scfa	serum_cytokines	0.262	0.394	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	IP-10	2-methyl-butyric acid m-C4+blood-CA+blood-L-Glutamine+blood-IP-10	Indirect	serum_scfa	serum_cytokines	0.262	0.394	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	IP-10	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+L-Glutamine+blood-IP-10	Indirect	serum_scfa	serum_cytokines	0.262	0.394	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	IP-10	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+L-Tryptophan+blood-IP-10	Indirect	serum_scfa	serum_cytokines	0.262	0.394	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	IP-10	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+Valine+blood-IP-10	Indirect	serum_scfa	serum_cytokines	0.262	0.394	no	no	no	no	no	no	DM-LS
DCA+blood	IP-10	DCA+blood-L-Glutamine+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.122	0.394	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IP-10	3-(3-Hydroxyphenyl)propanoic acid+stool+IP-10	Direct	stool_cometabolism	serum_cytokines	0.33	0.394	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+L-Tryptophan+stool+L-Tryptophan+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+L-Tryptophan+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+L-Tyrosine+stool+L-Tryptophan+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+L-Tyrosine+stool-16:0/22:6-PE+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-18:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+L-Tryptophan+stool-18:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-18:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+L-Tyrosine+stool-18:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+L-Tryptophan+stool+L-Ornithine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+L-Ornithine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+L-Tyrosine+stool+L-Ornithine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-Sarcosine+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	DM-LS
TCA+stool	IP-10	TCA+stool+18:0/18:0-PC+blood+L-2-Aminobutyric acid+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-LS
TCA+stool	IP-10	TCA+stool+18:0/18:1-PC+blood+L-2-Aminobutyric acid+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-LS
TCA+stool	IP-10	TCA+stool+18:0/18:0-PC+blood+18:1-LPC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-LS
TCA+stool	IP-10	TCA+stool+18:0/18:1-PC+blood+18:1-LPC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-LS
TCA+stool	IP-10	TCA+stool-Ethanolamine+blood+L-Tryptophan+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-LS
TCA+stool	IP-10	TCA+stool-Ethanolamine+blood+Valine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-LS
TCA+stool	IP-10	TCA+stool+18:1/18:1-PC+blood+Sarcosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-LS
TCA+stool	IP-10	TCA+stool+16:0/20:3-PC+blood+Sarcosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	DM-LS
HDCA+stool	IP-10	HDCA+stool-18:1-LPC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.176	0.394	no	no	no	no	no	no	DM-LS
Lachnospira	IP-10	Lachnospira-3-(3-Hydroxyphenyl)propanoic acid+stool+IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-LS
Lachnospira	IP-10	Lachnospira+18:0/20:5-PC+blood-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	DM-LS
Fusobacterium	IP-10	Fusobacterium+16:0/20:3-PC+blood+Sarcosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.628	0.394	no	no	no	no	no	no	DM-LS
Fusobacterium	IP-10	Fusobacterium+18:1/18:1-PC+blood+Sarcosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.628	0.394	no	no	no	no	no	no	DM-LS
Fusobacterium	IP-10	Fusobacterium+SFA%+blood+Valine+blood-IP-10	Indirect	Genus	serum_cytokines	0.628	0.394	no	no	no	no	no	no	DM-LS
isobutyric acid C4+blood	IP-10	isobutyric acid C4+blood+MUFA%+blood+SFA%+blood+Valine+blood-IP-10	Indirect	serum_scfa	serum_cytokines	0.0151	0.394	up	up	no	no	no	no	DM-LS
isobutyric acid C4+blood	IP-10	isobutyric acid C4+blood+MUFA%+blood-Eotaxin-IL-6-IP-10	Indirect	serum_scfa	serum_cytokines	0.0151	0.394	up	up	no	no	no	no	DM-LS
GCDCA+stool	IP-10	GCDCA+stool+18:0/18:0-PC+blood+18:1-LPC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IP-10	GCDCA+stool+18:0/18:1-PC+blood+18:1-LPC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IP-10	GCDCA+stool+24:1+blood+L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IP-10	GCDCA+stool+20:3/18:0-PC+blood+L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IP-10	GCDCA+stool-Creatinine+blood+L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IP-10	GCDCA+stool+CA+blood-L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IP-10	GCDCA+stool+18:0/18:0-PC+blood+L-2-Aminobutyric acid+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IP-10	GCDCA+stool+18:0/18:1-PC+blood+L-2-Aminobutyric acid+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IP-10	GCDCA+stool-L-Isoleucine+blood+L-Tryptophan+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IP-10	GCDCA+stool-L-Histidine+blood+L-Tryptophan+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IP-10	GCDCA+stool-L-Isoleucine+blood+L-Ornithine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IP-10	GCDCA+stool-L-Histidine+blood+L-Ornithine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IP-10	GCDCA+stool-L-Isoleucine+blood+Valine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IP-10	GCDCA+stool-L-Histidine+blood+Valine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IP-10	GCDCA+stool-L-Phenylalanine+blood+Valine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+L-Tryptophan+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool+L-Tyrosine+stool+L-Tryptophan+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool+L-Phenylalanine+stool-18:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool+L-Tyrosine+stool-18:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool-Acetic acid+stool+18:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+L-Ornithine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool+L-Tyrosine+stool+L-Ornithine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool+L-Tyrosine+stool-16:0/22:6-PE+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool-Acetic acid+stool+AA+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	DM-LS
Odoribacter	IP-10	Odoribacter-14:0/16:0-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-LS
Odoribacter	IP-10	Odoribacter-L-2-Aminobutyric acid+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool-UDCA+stool-18:0/20:5-PC+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+L-Tyrosine+stool-18:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool-UDCA+stool+18:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+L-Tryptophan+stool-18:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+Phenylacetic acid+stool-18:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+L-Phenylalanine+stool-18:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+L-Tyrosine+stool-16:0/22:6-PE+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+Phenylacetic acid+stool-Sarcosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+L-Tyrosine+stool+L-Ornithine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool-UDCA+stool-L-Ornithine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+L-Tryptophan+stool+L-Ornithine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+L-Phenylalanine+stool+L-Ornithine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+L-Tyrosine+stool+L-Tryptophan+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+L-Tryptophan+stool+L-Tryptophan+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+L-Phenylalanine+stool+L-Tryptophan+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	DM-LS
Lachnobacterium	IP-10	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-IL-6-IP-10	Indirect	Genus	serum_cytokines	0.867	0.394	no	no	no	no	no	no	DM-LS
Kynurenic acid+stool	IP-10	Kynurenic acid+stool+L-Tyrosine+stool-16:0/22:6-PE+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IP-10	Kynurenic acid+stool-UDCA+stool+18:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IP-10	Kynurenic acid+stool+L-Tyrosine+stool-18:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IP-10	Kynurenic acid+stool+L-Tyrosine+stool+L-Tryptophan+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IP-10	Kynurenic acid+stool-UDCA+stool-L-Ornithine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IP-10	Kynurenic acid+stool+L-Tyrosine+stool+L-Ornithine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IP-10	Kynurenic acid+stool-UDCA+stool-18:0/20:5-PC+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	DM-LS
Anaerostipes	IP-10	Anaerostipes-3-(3-Hydroxyphenyl)propanoic acid+stool+IP-10	Indirect	Genus	serum_cytokines	0.568	0.394	no	no	no	no	no	no	DM-LS
TUDCA+stool	IP-10	TUDCA+stool-UDCA+stool-L-Ornithine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.241	0.394	no	no	no	no	no	no	DM-LS
TUDCA+stool	IP-10	TUDCA+stool-UDCA+stool+18:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.241	0.394	no	no	no	no	no	no	DM-LS
TUDCA+stool	IP-10	TUDCA+stool-UDCA+stool-18:0/20:5-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.241	0.394	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+Phenylacetic acid+stool-Sarcosine+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+L-Phenylalanine+stool-18:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+Phenylacetic acid+stool-18:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool-UDCA+stool+18:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+L-Tyrosine+stool-18:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+L-Tryptophan+stool-18:3n6+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool-UDCA+stool-18:0/20:5-PC+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+L-Phenylalanine+stool+L-Tryptophan+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+L-Tyrosine+stool+L-Tryptophan+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+L-Tryptophan+stool+L-Tryptophan+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+L-Phenylalanine+stool+L-Ornithine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool-UDCA+stool-L-Ornithine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+L-Tyrosine+stool+L-Ornithine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+L-Tryptophan+stool+L-Ornithine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IP-10	Isovaleric acid+stool+L-Tyrosine+stool-16:0/22:6-PE+blood+IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	DM-LS
Paraprevotella	IP-10	Paraprevotella+Betaine+blood-IP-10	Indirect	Genus	serum_cytokines	0.118	0.394	no	no	no	no	no	no	DM-LS
iso-LCA+blood	IP-10	iso-LCA+blood-Sarcosine+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.507	0.394	no	no	no	no	no	no	DM-LS
iso-LCA+blood	IP-10	iso-LCA+blood+L-Ornithine+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.507	0.394	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	IP-10	Phenylacetic acid+stool-Sarcosine+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.785	0.394	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	IP-10	Phenylacetic acid+stool-18:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.785	0.394	no	no	no	no	no	no	DM-LS
Gemmiger	IP-10	Gemmiger-18:1-LPC+blood-IP-10	Indirect	Genus	serum_cytokines	0.595	0.394	no	no	no	no	no	no	DM-LS
GDCA+stool	IP-10	GDCA+stool+18:0/18:0-PC+blood+18:1-LPC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	DM-LS
GDCA+stool	IP-10	GDCA+stool-18:0/22:6-PE+blood-18:1-LPC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	DM-LS
GDCA+stool	IP-10	GDCA+stool+18:0/18:1-PC+blood+18:1-LPC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	DM-LS
GDCA+stool	IP-10	GDCA+stool-L-Histidine+blood+L-Tryptophan+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	DM-LS
GDCA+stool	IP-10	GDCA+stool-L-Isoleucine+blood+L-Tryptophan+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	DM-LS
GDCA+stool	IP-10	GDCA+stool+18:0/18:0-PC+blood+L-2-Aminobutyric acid+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	DM-LS
GDCA+stool	IP-10	GDCA+stool-18:0/22:6-PE+blood-L-2-Aminobutyric acid+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	DM-LS
GDCA+stool	IP-10	GDCA+stool+18:0/18:1-PC+blood+L-2-Aminobutyric acid+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	DM-LS
GDCA+stool	IP-10	GDCA+stool-L-Histidine+blood+L-Ornithine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	DM-LS
GDCA+stool	IP-10	GDCA+stool-L-Isoleucine+blood+L-Ornithine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	DM-LS
GDCA+stool	IP-10	GDCA+stool-L-Histidine+blood+Valine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	DM-LS
GDCA+stool	IP-10	GDCA+stool-L-Phenylalanine+blood+Valine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	DM-LS
GDCA+stool	IP-10	GDCA+stool-L-Isoleucine+blood+Valine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	DM-LS
GDCA+stool	IP-10	GDCA+stool+20:3/18:0-PC+blood+L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	DM-LS
GDCA+stool	IP-10	GDCA+stool+Glycine+blood+L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	DM-LS
GDCA+stool	IP-10	GDCA+stool+24:1+blood+L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IP-10	Methanobrevibacter+Valine+blood-IP-10	Indirect	Genus	serum_cytokines	0.629	0.394	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IP-10	Methanobrevibacter-Sarcosine+blood+IP-10	Indirect	Genus	serum_cytokines	0.629	0.394	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IP-10	Methanobrevibacter+L-Citrulline+blood-IP-10	Indirect	Genus	serum_cytokines	0.629	0.394	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IP-10	Methanobrevibacter+L-2-Aminobutyric acid+blood-IP-10	Indirect	Genus	serum_cytokines	0.629	0.394	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	IP-10	L-Tyrosine+stool+L-Ornithine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	IP-10	L-Tyrosine+stool-16:0/22:6-PE+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	IP-10	L-Tyrosine+stool+L-Tryptophan+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	IP-10	L-Tyrosine+stool-18:3n6+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	DM-LS
CDCA+stool	IP-10	CDCA+stool-L-Ornithine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.663	0.394	no	no	no	no	no	no	DM-LS
CDCA+stool	IP-10	CDCA+stool+18:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.663	0.394	no	no	no	no	no	no	DM-LS
CA+stool	IP-10	CA+stool-L-Ornithine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.827	0.394	no	no	no	no	no	no	DM-LS
CA+stool	IP-10	CA+stool+18:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.827	0.394	no	no	no	no	no	no	DM-LS
CA+stool	IP-10	CA+stool-18:0/20:5-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.827	0.394	no	no	no	no	no	no	DM-LS
Slackia	IP-10	Slackia-16:0/22:6-PE+blood+IP-10	Indirect	Genus	serum_cytokines	0.94	0.394	no	no	no	no	no	no	DM-LS
Slackia	IP-10	Slackia+14:0/18:2-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.94	0.394	no	no	no	no	no	no	DM-LS
Slackia	IP-10	Slackia-Neutrophil extracellular trap formation-IP-10	Indirect	Genus	serum_cytokines	0.94	0.394	no	no	no	no	no	no	DM-LS
HDCA+blood	IP-10	HDCA+blood-Sarcosine+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.483	0.394	no	no	no	no	no	no	DM-LS
HDCA+blood	IP-10	HDCA+blood+L-Ornithine+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.483	0.394	no	no	no	no	no	no	DM-LS
UDCA+stool	IP-10	UDCA+stool-L-Ornithine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.266	0.394	no	no	no	no	no	no	DM-LS
UDCA+stool	IP-10	UDCA+stool+18:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.266	0.394	no	no	no	no	no	no	DM-LS
UDCA+stool	IP-10	UDCA+stool-18:0/20:5-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.266	0.394	no	no	no	no	no	no	DM-LS
TDCA+stool	IP-10	TDCA+stool+UDCA+stool-L-Ornithine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.963	0.394	no	no	no	no	no	no	DM-LS
TDCA+stool	IP-10	TDCA+stool+UDCA+stool+18:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.963	0.394	no	no	no	no	no	no	DM-LS
TDCA+stool	IP-10	TDCA+stool+UDCA+stool-18:0/20:5-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.963	0.394	no	no	no	no	no	no	DM-LS
nutriCA+stool	IP-10	nutriCA+stool-Phenylacetic acid+stool-Sarcosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	DM-LS
nutriCA+stool	IP-10	nutriCA+stool-18:3n3+blood-Sarcosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	DM-LS
nutriCA+stool	IP-10	nutriCA+stool+UDCA+stool+18:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	DM-LS
nutriCA+stool	IP-10	nutriCA+stool-Phenylacetic acid+stool-18:3n6+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	DM-LS
nutriCA+stool	IP-10	nutriCA+stool+UDCA+stool-L-Ornithine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	DM-LS
nutriCA+stool	IP-10	nutriCA+stool+CA+blood-L-Glutamine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	DM-LS
nutriCA+stool	IP-10	nutriCA+stool-TXB2+blood+Valine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	DM-LS
nutriCA+stool	IP-10	nutriCA+stool-16:0/16:0-PC+blood+18:0/20:5-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	DM-LS
nutriCA+stool	IP-10	nutriCA+stool+UDCA+stool-18:0/20:5-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	DM-LS
GDCA+blood	IP-10	GDCA+blood+iso-LCA+blood-Sarcosine+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.632	0.394	no	no	no	no	no	no	DM-LS
GDCA+blood	IP-10	GDCA+blood+iso-LCA+blood+L-Ornithine+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.632	0.394	no	no	no	no	no	no	DM-LS
acetic acid C2+blood	IP-10	acetic acid C2+blood-Sarcosine+blood+IP-10	Indirect	serum_scfa	serum_cytokines	0.000193	0.394	up	dn	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	IP-10	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-IL-6-IP-10	Indirect	serum_scfa	serum_cytokines	0.117	0.394	no	no	no	no	no	no	DM-LS
Adlercreutzia	IP-10	Adlercreutzia-14:0+blood+IP-10	Indirect	Genus	serum_cytokines	0.548	0.394	no	no	no	no	no	no	DM-LS
Adlercreutzia	IP-10	Adlercreutzia-3-(3-Hydroxyphenyl)propanoic acid+stool+IP-10	Indirect	Genus	serum_cytokines	0.548	0.394	no	no	no	no	no	no	DM-LS
Adlercreutzia	IP-10	Adlercreutzia+18:1-LPC+blood-IP-10	Indirect	Genus	serum_cytokines	0.548	0.394	no	no	no	no	no	no	DM-LS
Clostridium	IP-10	Clostridium-14:0/16:0-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.925	0.394	no	no	no	no	no	no	DM-LS
Clostridium	IP-10	Clostridium-14:0/18:2-PC+blood+IP-10	Indirect	Genus	serum_cytokines	0.925	0.394	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IP-10	T-¦Á-MCA+stool-TCA+stool+18:0/18:0-PC+blood+L-2-Aminobutyric acid+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.48	0.394	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IP-10	T-¦Á-MCA+stool-TCA+stool+18:0/18:1-PC+blood+L-2-Aminobutyric acid+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.48	0.394	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IP-10	T-¦Á-MCA+stool-TCA+stool+18:0/18:0-PC+blood+18:1-LPC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.48	0.394	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IP-10	T-¦Á-MCA+stool-TCA+stool+18:0/18:1-PC+blood+18:1-LPC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.48	0.394	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IP-10	T-¦Á-MCA+stool-TCA+stool-Ethanolamine+blood+L-Tryptophan+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.48	0.394	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IP-10	T-¦Á-MCA+stool-TCA+stool-Ethanolamine+blood+Valine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.48	0.394	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IP-10	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+Sarcosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.48	0.394	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IP-10	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+Sarcosine+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.48	0.394	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-20:3-LPE+blood+Sarcosine+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IP-10	12-ketoDCA+blood+GLCA+blood-Sarcosine+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-8-HETE+blood+AA+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-20:4-LPC+blood+AA+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-20:0-LPC+blood+L-Citrulline+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-L-Arginine+blood+L-Citrulline+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-L-Lysine+blood+L-Tryptophan+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-20:3-LPE+blood-L-Ornithine+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-L-Lysine+blood+L-Ornithine+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-L-Lysine+blood+Valine+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-L-Arginine+blood+Valine+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-L-Arginine+blood+L-Glutamine+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	DM-LS
Butyricicoccus	IP-10	Butyricicoccus-IP-10	Direct	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	DM-LS
Blautia	IL-1b	Blautia-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	DM-LS
Parabacteroides	IL-1b	Parabacteroides-Glucagon signaling pathway+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.00358	no	up	up	up	up	no	DM-LS
Parabacteroides	IL-1b	Parabacteroides-Spliceosome+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.00358	no	up	up	up	up	no	DM-LS
Parabacteroides	IL-1b	Parabacteroides+Choline+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.00358	no	up	up	up	up	no	DM-LS
Dorea	IL-1b	Dorea-Lipid and atherosclerosis-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	DM-LS
Faecalibacterium	IL-1b	Faecalibacterium-Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.0039	0.00358	no	dn	dn	up	up	no	DM-LS
TUDCA+blood	IL-1b	TUDCA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0282	0.00358	no	no	dn	up	up	no	DM-LS
isocapric acid iso-C6+blood	IL-1b	isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_scfa	serum_cytokines	0.0458	0.00358	no	no	dn	up	up	no	DM-LS
Bacteroides	IL-1b	Bacteroides+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.000267	0.00358	dn	dn	up	up	up	no	DM-LS
Bacteroides	IL-1b	Bacteroides+22:6n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.000267	0.00358	dn	dn	up	up	up	no	DM-LS
Propionic acid+stool	IL-1b	Propionic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.00358	dn	no	up	up	up	no	DM-LS
Propionic acid+stool	IL-1b	Propionic acid+stool-MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.00358	dn	no	up	up	up	no	DM-LS
Propionic acid+stool	IL-1b	Propionic acid+stool-ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.00358	dn	no	up	up	up	no	DM-LS
[Ruminococcus]	IL-1b	[Ruminococcus]-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-LS
[Ruminococcus]	IL-1b	[Ruminococcus]-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-LS
[Ruminococcus]	IL-1b	[Ruminococcus]-MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	DM-LS
GUDCA+blood	IL-1b	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00358	no	no	dn	up	up	no	DM-LS
Acetic acid+stool	IL-1b	Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.0656	0.00358	dn	no	no	up	up	no	DM-LS
Acetic acid+stool	IL-1b	Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.0656	0.00358	dn	no	no	up	up	no	DM-LS
Alistipes	IL-1b	Alistipes-L-Arginine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-LS
Alistipes	IL-1b	Alistipes-HIF-1 signaling pathway+Measles-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-LS
Alistipes	IL-1b	Alistipes-L-Aspartic acid+blood+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	DM-LS
Butyricimonas	IL-1b	Butyricimonas+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.17	0.00358	no	no	no	up	up	no	DM-LS
Collinsella	IL-1b	Collinsella-Signaling pathways regulating pluripotency of stem cells+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-LS
Collinsella	IL-1b	Collinsella-Colorectal cancer+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-LS
Collinsella	IL-1b	Collinsella-Glioma+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-LS
Collinsella	IL-1b	Collinsella-Long-term potentiation+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-LS
Collinsella	IL-1b	Collinsella-Choline metabolism in cancer+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-LS
Collinsella	IL-1b	Collinsella-Gastric cancer+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-LS
Collinsella	IL-1b	Collinsella-ErbB signaling pathway+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-LS
Collinsella	IL-1b	Collinsella-Phosphatidylinositol signaling system+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	DM-LS
total_blood_scfa+blood	IL-1b	total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	serum_scfa	serum_cytokines	0.168	0.00358	no	no	no	up	up	no	DM-LS
[Eubacterium]	IL-1b	[Eubacterium]-Viral myocarditis-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.0692	0.00358	no	no	no	up	up	no	DM-LS
[Eubacterium]	IL-1b	[Eubacterium]-Pathogenic Escherichia coli infection-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.0692	0.00358	no	no	no	up	up	no	DM-LS
[Eubacterium]	IL-1b	[Eubacterium]-Phagosome-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.0692	0.00358	no	no	no	up	up	no	DM-LS
LCA+stool	IL-1b	LCA+stool-ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia+Apoptosis-Cushing syndrome+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia+LCA+stool-ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia-4-hydroxybenzoic acid+stool+ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia+Apoptosis+Viral myocarditis-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia+Apoptosis-Glucagon signaling pathway+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia+Apoptosis+Fc gamma R-mediated phagocytosis-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia+Apoptosis-Inflammatory mediator regulation of TRP channels+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia-18:0/18:2-PI+blood-Creatinine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia+Apoptosis+IL-17 signaling pathway-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia-18:0/18:2-PI+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia+Apoptosis+Neutrophil extracellular trap formation-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia+Apoptosis-Melanogenesis+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia-Retrograde endocannabinoid signaling-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia+Apoptosis-Long-term potentiation+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia+Apoptosis+Lipid and atherosclerosis-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia+Apoptosis+Pathogenic Escherichia coli infection-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia+Apoptosis+Systemic lupus erythematosus-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia-Retrograde endocannabinoid signaling+CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia+Apoptosis+Staphylococcus aureus infection-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia+Apoptosis-Aldosterone synthesis and secretion+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Akkermansia	IL-1b	Akkermansia+Apoptosis-Adrenergic signaling in cardiomyocytes+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	DM-LS
Bifidobacterium	IL-1b	Bifidobacterium+Chemical carcinogenesis - receptor activation+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	DM-LS
Ruminococcus	IL-1b	Ruminococcus+Type I diabetes mellitus-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	DM-LS
Ruminococcus	IL-1b	Ruminococcus+Endocytosis-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	DM-LS
Ruminococcus	IL-1b	Ruminococcus+Allograft rejection-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	DM-LS
Ruminococcus	IL-1b	Ruminococcus+22:6n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	DM-LS
Ruminococcus	IL-1b	Ruminococcus+Graft-versus-host disease-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	DM-LS
Ruminococcus	IL-1b	Ruminococcus+Phagosome-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	DM-LS
Ruminococcus	IL-1b	Ruminococcus+Cell adhesion molecules-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	DM-LS
Ruminococcus	IL-1b	Ruminococcus+Autoimmune thyroid disease-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	DM-LS
GCDCA+blood	IL-1b	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.00358	no	no	no	up	up	no	DM-LS
Succinivibrio	IL-1b	Succinivibrio-L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.138	0.00358	no	no	no	up	up	no	DM-LS
Succinivibrio	IL-1b	Succinivibrio-Phospholipase D signaling pathway+Cushing syndrome+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.138	0.00358	no	no	no	up	up	no	DM-LS
Succinivibrio	IL-1b	Succinivibrio-Phospholipase D signaling pathway-MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.138	0.00358	no	no	no	up	up	no	DM-LS
Succinivibrio	IL-1b	Succinivibrio-L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.138	0.00358	no	no	no	up	up	no	DM-LS
Succinivibrio	IL-1b	Succinivibrio-Phospholipase D signaling pathway+Chemical carcinogenesis - receptor activation+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.138	0.00358	no	no	no	up	up	no	DM-LS
Succinivibrio	IL-1b	Succinivibrio-L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.138	0.00358	no	no	no	up	up	no	DM-LS
Succinivibrio	IL-1b	Succinivibrio-L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.138	0.00358	no	no	no	up	up	no	DM-LS
Succinivibrio	IL-1b	Succinivibrio-Phospholipase D signaling pathway-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.138	0.00358	no	no	no	up	up	no	DM-LS
ACA+blood	IL-1b	ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.338	0.00358	no	no	no	up	up	no	DM-LS
DCA+stool	IL-1b	DCA+stool-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	DM-LS
DCA+stool	IL-1b	DCA+stool-ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	DM-LS
Butyric acid+stool	IL-1b	Butyric acid+stool+Propionic acid+stool-MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.00358	dn	no	no	up	up	no	DM-LS
Butyric acid+stool	IL-1b	Butyric acid+stool+8-HETE+blood-ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.00358	dn	no	no	up	up	no	DM-LS
Butyric acid+stool	IL-1b	Butyric acid+stool+Propionic acid+stool-ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.00358	dn	no	no	up	up	no	DM-LS
Butyric acid+stool	IL-1b	Butyric acid+stool-16:1/16:1-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.00358	dn	no	no	up	up	no	DM-LS
Butyric acid+stool	IL-1b	Butyric acid+stool+AA+blood+Choline+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.00358	dn	no	no	up	up	no	DM-LS
Butyric acid+stool	IL-1b	Butyric acid+stool+Propionic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.00358	dn	no	no	up	up	no	DM-LS
Butyric acid+stool	IL-1b	Butyric acid+stool-Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.00358	dn	no	no	up	up	no	DM-LS
4-hydroxybenzoic acid+stool	IL-1b	4-hydroxybenzoic acid+stool+ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.00358	no	dn	no	up	up	no	DM-LS
GCA+blood	IL-1b	GCA+blood+TCA+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.16	0.00358	no	no	no	up	up	no	DM-LS
ACA+stool	IL-1b	ACA+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.417	0.00358	no	no	no	up	up	no	DM-LS
ACA+stool	IL-1b	ACA+stool+20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.417	0.00358	no	no	no	up	up	no	DM-LS
CDCA+blood	IL-1b	CDCA+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.00358	no	no	no	up	up	no	DM-LS
CDCA+blood	IL-1b	CDCA+blood-Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.00358	no	no	no	up	up	no	DM-LS
capric acid C6+blood	IL-1b	capric acid C6+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_scfa	serum_cytokines	0.433	0.00358	no	no	no	up	up	no	DM-LS
capric acid C6+blood	IL-1b	capric acid C6+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	serum_scfa	serum_cytokines	0.433	0.00358	no	no	no	up	up	no	DM-LS
capric acid C6+blood	IL-1b	capric acid C6+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_scfa	serum_cytokines	0.433	0.00358	no	no	no	up	up	no	DM-LS
Pyramidobacter	IL-1b	Pyramidobacter-Carbon metabolism-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.45	0.00358	no	no	no	up	up	no	DM-LS
Pyramidobacter	IL-1b	Pyramidobacter+Glucagon signaling pathway+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.45	0.00358	no	no	no	up	up	no	DM-LS
Prevotella	IL-1b	Prevotella+Aldosterone synthesis and secretion+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	DM-LS
Prevotella	IL-1b	Prevotella+Adrenergic signaling in cardiomyocytes+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	DM-LS
Prevotella	IL-1b	Prevotella+Chemical carcinogenesis - receptor activation+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	DM-LS
Prevotella	IL-1b	Prevotella+Inflammatory mediator regulation of TRP channels+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	DM-LS
Prevotella	IL-1b	Prevotella-Carbon metabolism-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	DM-LS
Prevotella	IL-1b	Prevotella+Amphetamine addiction+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	DM-LS
Prevotella	IL-1b	Prevotella+Dopaminergic synapse+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	DM-LS
Prevotella	IL-1b	Prevotella+Cushing syndrome+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	DM-LS
Prevotella	IL-1b	Prevotella+Melanogenesis+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	DM-LS
TCA+blood	IL-1b	TCA+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.339	0.00358	no	no	no	up	up	no	DM-LS
iso-DCA+blood	IL-1b	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.38	0.00358	no	no	no	up	up	no	DM-LS
iso-DCA+blood	IL-1b	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.38	0.00358	no	no	no	up	up	no	DM-LS
iso-DCA+blood	IL-1b	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.38	0.00358	no	no	no	up	up	no	DM-LS
HCA+stool	IL-1b	HCA+stool-Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.00358	no	no	no	up	up	no	DM-LS
Roseburia	IL-1b	Roseburia-20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.495	0.00358	no	no	no	up	up	no	DM-LS
12-ketoDCA+stool	IL-1b	12-ketoDCA+stool+DCA+stool-ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.00358	no	no	no	up	up	no	DM-LS
12-ketoDCA+stool	IL-1b	12-ketoDCA+stool+LCA+stool-ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.00358	no	no	no	up	up	no	DM-LS
12-ketoDCA+stool	IL-1b	12-ketoDCA+stool+18:0/18:1-PE+blood-ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.00358	no	no	no	up	up	no	DM-LS
12-ketoDCA+stool	IL-1b	12-ketoDCA+stool+DCA+stool-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.00358	no	no	no	up	up	no	DM-LS
12-ketoDCA+stool	IL-1b	12-ketoDCA+stool-Glycine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.00358	no	no	no	up	up	no	DM-LS
12-ketoDCA+stool	IL-1b	12-ketoDCA+stool+18:0/18:1-PE+blood-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.00358	no	no	no	up	up	no	DM-LS
12-ketoDCA+stool	IL-1b	12-ketoDCA+stool-Glycine+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.00358	no	no	no	up	up	no	DM-LS
GLCA+blood	IL-1b	GLCA+blood-PUFA/MUFA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.319	0.00358	no	no	no	up	up	no	DM-LS
GLCA+blood	IL-1b	GLCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.319	0.00358	no	no	no	up	up	no	DM-LS
L-Tryptophan+stool	IL-1b	L-Tryptophan+stool+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00358	no	no	no	up	up	no	DM-LS
CA+blood	IL-1b	CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.606	0.00358	no	no	no	up	up	no	DM-LS
L-Phenylalanine+stool	IL-1b	L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00358	no	no	no	up	up	no	DM-LS
L-Phenylalanine+stool	IL-1b	L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00358	no	no	no	up	up	no	DM-LS
L-Phenylalanine+stool	IL-1b	L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00358	no	no	no	up	up	no	DM-LS
butyric acid C4+blood	IL-1b	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_scfa	serum_cytokines	0.407	0.00358	no	no	no	up	up	no	DM-LS
GCA+stool	IL-1b	GCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	DM-LS
GCA+stool	IL-1b	GCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	DM-LS
GCA+stool	IL-1b	GCA+stool+nutriCA+stool+CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	DM-LS
GCA+stool	IL-1b	GCA+stool+GCDCA+stool+CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	DM-LS
GCA+stool	IL-1b	GCA+stool+nutriCA+stool-n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	DM-LS
GCA+stool	IL-1b	GCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	DM-LS
GCA+stool	IL-1b	GCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	DM-LS
GCA+stool	IL-1b	GCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	DM-LS
GCA+stool	IL-1b	GCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	DM-LS
GCA+stool	IL-1b	GCA+stool+GCDCA+stool-Creatinine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	DM-LS
GCA+stool	IL-1b	GCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	DM-LS
GCA+stool	IL-1b	GCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	DM-LS
T-a-MCA+blood	IL-1b	T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.478	0.00358	no	no	no	up	up	no	DM-LS
Coprococcus	IL-1b	Coprococcus-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	DM-LS
Oscillospira	IL-1b	Oscillospira-Adrenergic signaling in cardiomyocytes+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-LS
Oscillospira	IL-1b	Oscillospira+Peroxisome-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	DM-LS
HCA+blood	IL-1b	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.544	0.00358	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-1b	iso-LCA+stool-CDCA+blood-Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-1b	iso-LCA+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-1b	iso-LCA+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-1b	iso-LCA+stool-18:3n6+blood-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-1b	iso-LCA+stool-nutriCA+stool+CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-1b	iso-LCA+stool-18:3n6+blood-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-1b	iso-LCA+stool-Glycine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-1b	iso-LCA+stool-nutriCA+stool-n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-1b	iso-LCA+stool-18:1-LPE+blood-n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-1b	iso-LCA+stool-Sarcosine+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-1b	iso-LCA+stool-18:1-LPE+blood-22:6n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-1b	iso-LCA+stool-CDCA+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-1b	iso-LCA+stool-Glycine+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	DM-LS
iso-LCA+stool	IL-1b	iso-LCA+stool+LCA+stool-ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	DM-LS
2-methyl-butyric acid m-C4+blood	IL-1b	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.00358	no	no	no	up	up	no	DM-LS
DCA+blood	IL-1b	DCA+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2/16:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool+UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-16:0/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2n6c+blood+20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	DM-LS
Indole-3-Acetic acid+stool	IL-1b	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00358	no	no	no	up	up	no	DM-LS
Indole-3-Acetic acid+stool	IL-1b	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00358	no	no	no	up	up	no	DM-LS
Indole-3-Acetic acid+stool	IL-1b	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00358	no	no	no	up	up	no	DM-LS
Indole-3-Acetic acid+stool	IL-1b	Indole-3-Acetic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00358	no	no	no	up	up	no	DM-LS
Indole-3-Acetic acid+stool	IL-1b	Indole-3-Acetic acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00358	no	no	no	up	up	no	DM-LS
Indole-3-Acetic acid+stool	IL-1b	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00358	no	no	no	up	up	no	DM-LS
TCA+stool	IL-1b	TCA+stool-16:0/20:5-PC+blood+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-LS
TCA+stool	IL-1b	TCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-LS
TCA+stool	IL-1b	TCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-LS
TCA+stool	IL-1b	TCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-LS
TCA+stool	IL-1b	TCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-LS
TCA+stool	IL-1b	TCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-LS
TCA+stool	IL-1b	TCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-LS
TCA+stool	IL-1b	TCA+stool-16:0/20:5-PC+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-LS
TCA+stool	IL-1b	TCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-LS
TCA+stool	IL-1b	TCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-LS
TCA+stool	IL-1b	TCA+stool+18:1/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-LS
TCA+stool	IL-1b	TCA+stool+16:0/20:3-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-LS
TCA+stool	IL-1b	TCA+stool-16:0/20:5-PC+blood-20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-LS
TCA+stool	IL-1b	TCA+stool+18:1/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-LS
TCA+stool	IL-1b	TCA+stool+16:0/20:3-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-LS
TCA+stool	IL-1b	TCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-LS
TCA+stool	IL-1b	TCA+stool-16:0/20:5-PC+blood+CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-1b	HDCA+stool-18:1/20:3-PC+blood-CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-1b	HDCA+stool-nutriCA+stool+CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-1b	HDCA+stool+LCA+stool-ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-1b	HDCA+stool-18:1-LPE+blood-22:6n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-1b	HDCA+stool-18:1/20:3-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-1b	HDCA+stool-18:1-LPC+blood+20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-1b	HDCA+stool-16:0/20:3-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-1b	HDCA+stool-18:1/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-1b	HDCA+stool+EPA+blood+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-1b	HDCA+stool-nutriCA+stool-n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-1b	HDCA+stool-18:1-LPE+blood-n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-1b	HDCA+stool-16:0/20:3-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	DM-LS
HDCA+stool	IL-1b	HDCA+stool-18:1/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	DM-LS
Lachnospira	IL-1b	Lachnospira+Choline+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.279	0.00358	no	no	no	up	up	no	DM-LS
Fusobacterium	IL-1b	Fusobacterium+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.628	0.00358	no	no	no	up	up	no	DM-LS
Fusobacterium	IL-1b	Fusobacterium+MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.628	0.00358	no	no	no	up	up	no	DM-LS
isobutyric acid C4+blood	IL-1b	isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_scfa	serum_cytokines	0.0151	0.00358	up	up	no	up	up	no	DM-LS
GCDCA+stool	IL-1b	GCDCA+stool-Creatinine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	DM-LS
GCDCA+stool	IL-1b	GCDCA+stool+CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-Propionic acid+stool-ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-Propionic acid+stool-MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-Propionic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-LS
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	DM-LS
Odoribacter	IL-1b	Odoribacter+Choline+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-1b	Isobutyric acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.00358	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-1b	Isobutyric acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.00358	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-1b	Isobutyric acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.00358	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-1b	Isobutyric acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.00358	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-1b	Isobutyric acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.00358	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-1b	Isobutyric acid+stool-nutriCA+stool+CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.00358	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-1b	Isobutyric acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.00358	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-1b	Isobutyric acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.00358	no	no	no	up	up	no	DM-LS
Isobutyric acid+stool	IL-1b	Isobutyric acid+stool-nutriCA+stool-n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.00358	no	no	no	up	up	no	DM-LS
Lachnobacterium	IL-1b	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.867	0.00358	no	no	no	up	up	no	DM-LS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-nutriCA+stool+CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-LS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-nutriCA+stool-n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-LS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-LS
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	DM-LS
Anaerostipes	IL-1b	Anaerostipes-Non-small cell lung cancer+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.568	0.00358	no	no	no	up	up	no	DM-LS
Anaerostipes	IL-1b	Anaerostipes+TUDCA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.568	0.00358	no	no	no	up	up	no	DM-LS
TUDCA+stool	IL-1b	TUDCA+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.241	0.00358	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-1b	Isovaleric acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.00358	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-1b	Isovaleric acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.00358	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-1b	Isovaleric acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.00358	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-1b	Isovaleric acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.00358	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-1b	Isovaleric acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.00358	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-1b	Isovaleric acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.00358	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-1b	Isovaleric acid+stool-nutriCA+stool-n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.00358	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-1b	Isovaleric acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.00358	no	no	no	up	up	no	DM-LS
Isovaleric acid+stool	IL-1b	Isovaleric acid+stool-nutriCA+stool+CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Arachidonic acid metabolism+Biosynthesis of amino acids-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Betaine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Glutathione metabolism-Choline metabolism in cancer+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Arachidonic acid metabolism-Choline metabolism in cancer+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Glutathione metabolism-Cholinergic synapse+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Glutathione metabolism-mRNA surveillance pathway+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Arachidonic acid metabolism-mRNA surveillance pathway+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Glutathione metabolism-Non-small cell lung cancer+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Arachidonic acid metabolism-Non-small cell lung cancer+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+18:0/20:2-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Glutathione metabolism-Colorectal cancer+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Arachidonic acid metabolism-Colorectal cancer+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Arachidonic acid metabolism-Cell cycle+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Arachidonic acid metabolism+Choline+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Glutathione metabolism-ErbB signaling pathway+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Arachidonic acid metabolism-ErbB signaling pathway+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Glutathione metabolism-Phosphatidylinositol signaling system+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Arachidonic acid metabolism-Phosphatidylinositol signaling system+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella-18:0/22:6-PA+blood+22:6n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Glutathione metabolism-Gastric cancer+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Arachidonic acid metabolism-Gastric cancer+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Glutathione metabolism-Glioma+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Arachidonic acid metabolism-Glioma+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Glutathione metabolism-Signaling pathways regulating pluripotency of stem cells+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Arachidonic acid metabolism-Signaling pathways regulating pluripotency of stem cells+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Glutathione metabolism-Spliceosome+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Arachidonic acid metabolism-Spliceosome+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Betaine+blood-CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Glutathione metabolism-Long-term potentiation+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
Paraprevotella	IL-1b	Paraprevotella+Arachidonic acid metabolism-Long-term potentiation+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	DM-LS
iso-LCA+blood	IL-1b	iso-LCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.507	0.00358	no	no	no	up	up	no	DM-LS
Phenylacetic acid+stool	IL-1b	Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.00358	no	no	no	up	up	no	DM-LS
Gemmiger	IL-1b	Gemmiger-18:1-LPC+blood+20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-LS
Gemmiger	IL-1b	Gemmiger+L-Phenylalanine+blood+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-1b	GDCA+stool-L-Phenylalanine+blood+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-1b	GDCA+stool-L-Isoleucine+blood+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-1b	GDCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-1b	GDCA+stool-L-Histidine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-1b	GDCA+stool+20:3/18:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-1b	GDCA+stool-L-Isoleucine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-1b	GDCA+stool+Glycine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-1b	GDCA+stool+24:1+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-1b	GDCA+stool-Propionic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-1b	GDCA+stool-L-Histidine+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-1b	GDCA+stool+Glycine+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-1b	GDCA+stool-Propionic acid+stool-MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-1b	GDCA+stool+20:3/18:0-PC+blood+ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-1b	GDCA+stool+24:1+blood+ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-1b	GDCA+stool-Propionic acid+stool-ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-LS
GDCA+stool	IL-1b	GDCA+stool+20:3/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	DM-LS
Methanobrevibacter	IL-1b	Methanobrevibacter+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.629	0.00358	no	no	no	up	up	no	DM-LS
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	DM-LS
CDCA+stool	IL-1b	CDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.00358	no	no	no	up	up	no	DM-LS
CA+stool	IL-1b	CA+stool+CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	DM-LS
Slackia	IL-1b	Slackia+Platinum drug resistance+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.94	0.00358	no	no	no	up	up	no	DM-LS
Slackia	IL-1b	Slackia-Neutrophil extracellular trap formation-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.94	0.00358	no	no	no	up	up	no	DM-LS
Slackia	IL-1b	Slackia-Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.94	0.00358	no	no	no	up	up	no	DM-LS
HDCA+blood	IL-1b	HDCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.483	0.00358	no	no	no	up	up	no	DM-LS
UDCA+stool	IL-1b	UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.00358	no	no	no	up	up	no	DM-LS
TDCA+stool	IL-1b	TDCA+stool+UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.963	0.00358	no	no	no	up	up	no	DM-LS
nutriCA+stool	IL-1b	nutriCA+stool+CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.00358	no	no	no	up	up	no	DM-LS
nutriCA+stool	IL-1b	nutriCA+stool-n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.00358	no	no	no	up	up	no	DM-LS
GDCA+blood	IL-1b	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.632	0.00358	no	no	no	up	up	no	DM-LS
acetic acid C2+blood	IL-1b	acetic acid C2+blood+total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.00358	up	dn	no	up	up	no	DM-LS
acetic acid C2+blood	IL-1b	acetic acid C2+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.00358	up	dn	no	up	up	no	DM-LS
acetic acid C2+blood	IL-1b	acetic acid C2+blood+capric acid C6+blood+TUDCA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.00358	up	dn	no	up	up	no	DM-LS
acetic acid C2+blood	IL-1b	acetic acid C2+blood+capric acid C6+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.00358	up	dn	no	up	up	no	DM-LS
acetic acid C2+blood	IL-1b	acetic acid C2+blood-d18:1-14:1-SM+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.00358	up	dn	no	up	up	no	DM-LS
acetic acid C2+blood	IL-1b	acetic acid C2+blood+capric acid C6+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.00358	up	dn	no	up	up	no	DM-LS
acetic acid C2+blood	IL-1b	acetic acid C2+blood-d18:1-14:1-SM+blood-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.00358	up	dn	no	up	up	no	DM-LS
isovaleric acid iso-C5+blood	IL-1b	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	serum_scfa	serum_cytokines	0.117	0.00358	no	no	no	up	up	no	DM-LS
Adlercreutzia	IL-1b	Adlercreutzia-16:0/20:5-PC+blood-20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.548	0.00358	no	no	no	up	up	no	DM-LS
Adlercreutzia	IL-1b	Adlercreutzia+18:1-LPC+blood+20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.548	0.00358	no	no	no	up	up	no	DM-LS
Adlercreutzia	IL-1b	Adlercreutzia-EPA+blood+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.548	0.00358	no	no	no	up	up	no	DM-LS
Adlercreutzia	IL-1b	Adlercreutzia-16:0/20:5-PC+blood+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.548	0.00358	no	no	no	up	up	no	DM-LS
Adlercreutzia	IL-1b	Adlercreutzia-16:0/20:5-PC+blood+CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.548	0.00358	no	no	no	up	up	no	DM-LS
Adlercreutzia	IL-1b	Adlercreutzia-16:0/20:5-PC+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.548	0.00358	no	no	no	up	up	no	DM-LS
Adlercreutzia	IL-1b	Adlercreutzia+16:0/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.548	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium+cGMP-PKG signaling pathway+Lipid and atherosclerosis-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium+cGMP-PKG signaling pathway+Endocytosis-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium+cGMP-PKG signaling pathway+IL-17 signaling pathway-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium+PUFA/MUFA+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium-14:0/20:4-PC+blood-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium-Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
 Clostridium	IL-1b	Clostridium+Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	NA	0.00358	NA	NA	NA	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium-Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
 Clostridium	IL-1b	Clostridium+Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	NA	0.00358	NA	NA	NA	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium+cGMP-PKG signaling pathway+Fc gamma R-mediated phagocytosis-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium+cGMP-PKG signaling pathway+Neutrophil extracellular trap formation-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium+cGMP-PKG signaling pathway+Pathogenic Escherichia coli infection-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium-18:0/20:2-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium+CDCA+blood-Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium-14:0/20:4-PC+blood-Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium-Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
 Clostridium	IL-1b	Clostridium+Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	NA	0.00358	NA	NA	NA	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium-Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
 Clostridium	IL-1b	Clostridium+Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	NA	0.00358	NA	NA	NA	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium-14:0/20:4-PC+blood-Creatinine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium-14:0/18:2-PC+blood-Creatinine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium-14:0/20:4-PC+blood-20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium+CDCA+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium-14:0/20:4-PC+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium+cGMP-PKG signaling pathway+MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
Clostridium	IL-1b	Clostridium-14:0/18:2-PC+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood-MUFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood-20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-TCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-LS
T-¦Á-MCA+stool	IL-1b	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+CA+blood+Eotaxin-GM-CSF+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.00358	no	no	no	up	up	no	DM-LS
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-8-HETE+blood-ACA+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	DM-LS
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-20:3-LPE+blood-22:6n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	DM-LS
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-20:3-LPE+blood+Choline+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	DM-LS
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-L-Lysine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	DM-LS
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-L-Arginine+blood+UFA%+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	DM-LS
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-20:3-LPE+blood-n3+blood-Eotaxin-GM-CSF+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	DM-LS
Butyricicoccus	IL-1b	Butyricicoccus+Allograft rejection-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	DM-LS
Butyricicoccus	IL-1b	Butyricicoccus+Viral myocarditis-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	DM-LS
Butyricicoccus	IL-1b	Butyricicoccus+Cell adhesion molecules-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	DM-LS
Butyricicoccus	IL-1b	Butyricicoccus+Type I diabetes mellitus-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	DM-LS
Butyricicoccus	IL-1b	Butyricicoccus+Graft-versus-host disease-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	DM-LS
Butyricicoccus	IL-1b	Butyricicoccus+Phagosome-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	DM-LS
Butyricicoccus	IL-1b	Butyricicoccus+Autoimmune thyroid disease-Eotaxin-GM-CSF+IL-1b	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	DM-LS
Blautia	GM-CSF	Blautia-20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	1.36E-05	0.0124	up	dn	dn	up	no	no	DM-LS
Parabacteroides	GM-CSF	Parabacteroides-Glucagon signaling pathway+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	4.19E-05	0.0124	no	up	up	up	no	no	DM-LS
Parabacteroides	GM-CSF	Parabacteroides-Spliceosome+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	4.19E-05	0.0124	no	up	up	up	no	no	DM-LS
Parabacteroides	GM-CSF	Parabacteroides+Choline+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	4.19E-05	0.0124	no	up	up	up	no	no	DM-LS
Dorea	GM-CSF	Dorea-Lipid and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.00362	0.0124	up	no	dn	up	no	no	DM-LS
Faecalibacterium	GM-CSF	Faecalibacterium-Cysteine+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0039	0.0124	no	dn	dn	up	no	no	DM-LS
TUDCA+blood	GM-CSF	TUDCA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.0282	0.0124	no	no	dn	up	no	no	DM-LS
isocapric acid iso-C6+blood	GM-CSF	isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.0458	0.0124	no	no	dn	up	no	no	DM-LS
Bacteroides	GM-CSF	Bacteroides+n3+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-LS
Bacteroides	GM-CSF	Bacteroides+22:6n3+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.000267	0.0124	dn	dn	up	up	no	no	DM-LS
Propionic acid+stool	GM-CSF	Propionic acid+stool-UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.0436	0.0124	dn	no	up	up	no	no	DM-LS
Propionic acid+stool	GM-CSF	Propionic acid+stool-MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.0436	0.0124	dn	no	up	up	no	no	DM-LS
Propionic acid+stool	GM-CSF	Propionic acid+stool-ACA+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.0436	0.0124	dn	no	up	up	no	no	DM-LS
[Ruminococcus]	GM-CSF	[Ruminococcus]-UFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0679	0.0124	no	no	dn	up	no	no	DM-LS
[Ruminococcus]	GM-CSF	[Ruminococcus]-20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0679	0.0124	no	no	dn	up	no	no	DM-LS
[Ruminococcus]	GM-CSF	[Ruminococcus]-MUFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0679	0.0124	no	no	dn	up	no	no	DM-LS
GUDCA+blood	GM-CSF	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0124	no	no	dn	up	no	no	DM-LS
Acetic acid+stool	GM-CSF	Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.0656	0.0124	dn	no	no	up	no	no	DM-LS
Acetic acid+stool	GM-CSF	Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.0656	0.0124	dn	no	no	up	no	no	DM-LS
Alistipes	GM-CSF	Alistipes-L-Arginine+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0114	0.0124	no	up	no	up	no	no	DM-LS
Alistipes	GM-CSF	Alistipes-HIF-1 signaling pathway+Measles-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0114	0.0124	no	up	no	up	no	no	DM-LS
Alistipes	GM-CSF	Alistipes-L-Aspartic acid+blood+n3+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0114	0.0124	no	up	no	up	no	no	DM-LS
Butyricimonas	GM-CSF	Butyricimonas+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.17	0.0124	no	no	no	up	no	no	DM-LS
Collinsella	GM-CSF	Collinsella-Signaling pathways regulating pluripotency of stem cells+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-LS
Collinsella	GM-CSF	Collinsella-Colorectal cancer+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-LS
Collinsella	GM-CSF	Collinsella-Glioma+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-LS
Collinsella	GM-CSF	Collinsella-Long-term potentiation+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-LS
Collinsella	GM-CSF	Collinsella-Choline metabolism in cancer+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-LS
Collinsella	GM-CSF	Collinsella-Gastric cancer+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-LS
Collinsella	GM-CSF	Collinsella-ErbB signaling pathway+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-LS
Collinsella	GM-CSF	Collinsella-Phosphatidylinositol signaling system+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.128	0.0124	no	no	no	up	no	no	DM-LS
total_blood_scfa+blood	GM-CSF	total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.168	0.0124	no	no	no	up	no	no	DM-LS
[Eubacterium]	GM-CSF	[Eubacterium]-Viral myocarditis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0692	0.0124	no	no	no	up	no	no	DM-LS
[Eubacterium]	GM-CSF	[Eubacterium]-Pathogenic Escherichia coli infection-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0692	0.0124	no	no	no	up	no	no	DM-LS
[Eubacterium]	GM-CSF	[Eubacterium]-Phagosome-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.0692	0.0124	no	no	no	up	no	no	DM-LS
LCA+stool	GM-CSF	LCA+stool-ACA+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.314	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia+Apoptosis-Cushing syndrome+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia+LCA+stool-ACA+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia-4-hydroxybenzoic acid+stool+ACA+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia+Apoptosis+Viral myocarditis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia+Apoptosis-Glucagon signaling pathway+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia+Apoptosis+Fc gamma R-mediated phagocytosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia+Apoptosis-Inflammatory mediator regulation of TRP channels+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia-18:0/18:2-PI+blood-Creatinine+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia+Apoptosis+IL-17 signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia-18:0/18:2-PI+blood-TUDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia+Apoptosis+Neutrophil extracellular trap formation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia+Apoptosis-Melanogenesis+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia-Retrograde endocannabinoid signaling-20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia+Apoptosis-Long-term potentiation+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia+Apoptosis+Lipid and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia+Apoptosis+Pathogenic Escherichia coli infection-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia+Apoptosis+Systemic lupus erythematosus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia-Retrograde endocannabinoid signaling+CA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia+Apoptosis+Staphylococcus aureus infection-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia+Apoptosis-Aldosterone synthesis and secretion+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Akkermansia	GM-CSF	Akkermansia+Apoptosis-Adrenergic signaling in cardiomyocytes+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.23	0.0124	no	no	no	up	no	no	DM-LS
Bifidobacterium	GM-CSF	Bifidobacterium+Chemical carcinogenesis - receptor activation+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.105	0.0124	no	dn	no	up	no	no	DM-LS
Ruminococcus	GM-CSF	Ruminococcus+Type I diabetes mellitus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.335	0.0124	no	no	no	up	no	no	DM-LS
Ruminococcus	GM-CSF	Ruminococcus+Endocytosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.335	0.0124	no	no	no	up	no	no	DM-LS
Ruminococcus	GM-CSF	Ruminococcus+Allograft rejection-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.335	0.0124	no	no	no	up	no	no	DM-LS
Ruminococcus	GM-CSF	Ruminococcus+22:6n3+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.335	0.0124	no	no	no	up	no	no	DM-LS
Ruminococcus	GM-CSF	Ruminococcus+Graft-versus-host disease-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.335	0.0124	no	no	no	up	no	no	DM-LS
Ruminococcus	GM-CSF	Ruminococcus+Phagosome-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.335	0.0124	no	no	no	up	no	no	DM-LS
Ruminococcus	GM-CSF	Ruminococcus+Cell adhesion molecules-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.335	0.0124	no	no	no	up	no	no	DM-LS
Ruminococcus	GM-CSF	Ruminococcus+Autoimmune thyroid disease-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.335	0.0124	no	no	no	up	no	no	DM-LS
GCDCA+blood	GM-CSF	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.31	0.0124	no	no	no	up	no	no	DM-LS
Succinivibrio	GM-CSF	Succinivibrio-L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.138	0.0124	no	no	no	up	no	no	DM-LS
Succinivibrio	GM-CSF	Succinivibrio-Phospholipase D signaling pathway+Cushing syndrome+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.138	0.0124	no	no	no	up	no	no	DM-LS
Succinivibrio	GM-CSF	Succinivibrio-Phospholipase D signaling pathway-MUFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.138	0.0124	no	no	no	up	no	no	DM-LS
Succinivibrio	GM-CSF	Succinivibrio-L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.138	0.0124	no	no	no	up	no	no	DM-LS
Succinivibrio	GM-CSF	Succinivibrio-Phospholipase D signaling pathway+Chemical carcinogenesis - receptor activation+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.138	0.0124	no	no	no	up	no	no	DM-LS
Succinivibrio	GM-CSF	Succinivibrio-L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.138	0.0124	no	no	no	up	no	no	DM-LS
Succinivibrio	GM-CSF	Succinivibrio-L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.138	0.0124	no	no	no	up	no	no	DM-LS
Succinivibrio	GM-CSF	Succinivibrio-Phospholipase D signaling pathway-UFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.138	0.0124	no	no	no	up	no	no	DM-LS
ACA+blood	GM-CSF	ACA+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.338	0.0124	no	no	no	up	no	no	DM-LS
DCA+stool	GM-CSF	DCA+stool-UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.195	0.0124	no	no	no	up	no	no	DM-LS
DCA+stool	GM-CSF	DCA+stool-ACA+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.195	0.0124	no	no	no	up	no	no	DM-LS
Butyric acid+stool	GM-CSF	Butyric acid+stool+Propionic acid+stool-MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.102	0.0124	dn	no	no	up	no	no	DM-LS
Butyric acid+stool	GM-CSF	Butyric acid+stool+8-HETE+blood-ACA+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.102	0.0124	dn	no	no	up	no	no	DM-LS
Butyric acid+stool	GM-CSF	Butyric acid+stool+Propionic acid+stool-ACA+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.102	0.0124	dn	no	no	up	no	no	DM-LS
Butyric acid+stool	GM-CSF	Butyric acid+stool-16:1/16:1-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.102	0.0124	dn	no	no	up	no	no	DM-LS
Butyric acid+stool	GM-CSF	Butyric acid+stool+AA+blood+Choline+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.102	0.0124	dn	no	no	up	no	no	DM-LS
Butyric acid+stool	GM-CSF	Butyric acid+stool+Propionic acid+stool-UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.102	0.0124	dn	no	no	up	no	no	DM-LS
Butyric acid+stool	GM-CSF	Butyric acid+stool-Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.102	0.0124	dn	no	no	up	no	no	DM-LS
4-hydroxybenzoic acid+stool	GM-CSF	4-hydroxybenzoic acid+stool+ACA+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.0124	no	dn	no	up	no	no	DM-LS
GCA+blood	GM-CSF	GCA+blood+TCA+blood+TUDCA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.16	0.0124	no	no	no	up	no	no	DM-LS
ACA+stool	GM-CSF	ACA+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.417	0.0124	no	no	no	up	no	no	DM-LS
ACA+stool	GM-CSF	ACA+stool+20:2+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.417	0.0124	no	no	no	up	no	no	DM-LS
CDCA+blood	GM-CSF	CDCA+blood-MUFA%+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.506	0.0124	no	no	no	up	no	no	DM-LS
CDCA+blood	GM-CSF	CDCA+blood-Cysteine+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.506	0.0124	no	no	no	up	no	no	DM-LS
capric acid C6+blood	GM-CSF	capric acid C6+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.433	0.0124	no	no	no	up	no	no	DM-LS
capric acid C6+blood	GM-CSF	capric acid C6+blood+TUDCA+blood+Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.433	0.0124	no	no	no	up	no	no	DM-LS
capric acid C6+blood	GM-CSF	capric acid C6+blood+MUFA%+blood-Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.433	0.0124	no	no	no	up	no	no	DM-LS
Pyramidobacter	GM-CSF	Pyramidobacter-Carbon metabolism-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.45	0.0124	no	no	no	up	no	no	DM-LS
Pyramidobacter	GM-CSF	Pyramidobacter+Glucagon signaling pathway+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.45	0.0124	no	no	no	up	no	no	DM-LS
Prevotella	GM-CSF	Prevotella+Aldosterone synthesis and secretion+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.287	0.0124	no	no	no	up	no	no	DM-LS
Prevotella	GM-CSF	Prevotella+Adrenergic signaling in cardiomyocytes+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.287	0.0124	no	no	no	up	no	no	DM-LS
Prevotella	GM-CSF	Prevotella+Chemical carcinogenesis - receptor activation+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.287	0.0124	no	no	no	up	no	no	DM-LS
Prevotella	GM-CSF	Prevotella+Inflammatory mediator regulation of TRP channels+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.287	0.0124	no	no	no	up	no	no	DM-LS
Prevotella	GM-CSF	Prevotella-Carbon metabolism-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.287	0.0124	no	no	no	up	no	no	DM-LS
Prevotella	GM-CSF	Prevotella+Amphetamine addiction+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.287	0.0124	no	no	no	up	no	no	DM-LS
Prevotella	GM-CSF	Prevotella+Dopaminergic synapse+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.287	0.0124	no	no	no	up	no	no	DM-LS
Prevotella	GM-CSF	Prevotella+Cushing syndrome+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.287	0.0124	no	no	no	up	no	no	DM-LS
Prevotella	GM-CSF	Prevotella+Melanogenesis+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.287	0.0124	no	no	no	up	no	no	DM-LS
TCA+blood	GM-CSF	TCA+blood+TUDCA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.339	0.0124	no	no	no	up	no	no	DM-LS
iso-DCA+blood	GM-CSF	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.38	0.0124	no	no	no	up	no	no	DM-LS
iso-DCA+blood	GM-CSF	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.38	0.0124	no	no	no	up	no	no	DM-LS
iso-DCA+blood	GM-CSF	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.38	0.0124	no	no	no	up	no	no	DM-LS
HCA+stool	GM-CSF	HCA+stool-Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.155	0.0124	no	no	no	up	no	no	DM-LS
Roseburia	GM-CSF	Roseburia-20:2+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.495	0.0124	no	no	no	up	no	no	DM-LS
12-ketoDCA+stool	GM-CSF	12-ketoDCA+stool+DCA+stool-ACA+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.505	0.0124	no	no	no	up	no	no	DM-LS
12-ketoDCA+stool	GM-CSF	12-ketoDCA+stool+LCA+stool-ACA+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.505	0.0124	no	no	no	up	no	no	DM-LS
12-ketoDCA+stool	GM-CSF	12-ketoDCA+stool+18:0/18:1-PE+blood-ACA+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.505	0.0124	no	no	no	up	no	no	DM-LS
12-ketoDCA+stool	GM-CSF	12-ketoDCA+stool+DCA+stool-UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.505	0.0124	no	no	no	up	no	no	DM-LS
12-ketoDCA+stool	GM-CSF	12-ketoDCA+stool-Glycine+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.505	0.0124	no	no	no	up	no	no	DM-LS
12-ketoDCA+stool	GM-CSF	12-ketoDCA+stool+18:0/18:1-PE+blood-UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.505	0.0124	no	no	no	up	no	no	DM-LS
12-ketoDCA+stool	GM-CSF	12-ketoDCA+stool-Glycine+blood+MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.505	0.0124	no	no	no	up	no	no	DM-LS
GLCA+blood	GM-CSF	GLCA+blood-PUFA/MUFA+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.319	0.0124	no	no	no	up	no	no	DM-LS
GLCA+blood	GM-CSF	GLCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.319	0.0124	no	no	no	up	no	no	DM-LS
L-Tryptophan+stool	GM-CSF	L-Tryptophan+stool+n3+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0124	no	no	no	up	no	no	DM-LS
CA+blood	GM-CSF	CA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.606	0.0124	no	no	no	up	no	no	DM-LS
L-Phenylalanine+stool	GM-CSF	L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0124	no	no	no	up	no	no	DM-LS
L-Phenylalanine+stool	GM-CSF	L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0124	no	no	no	up	no	no	DM-LS
L-Phenylalanine+stool	GM-CSF	L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0124	no	no	no	up	no	no	DM-LS
butyric acid C4+blood	GM-CSF	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.407	0.0124	no	no	no	up	no	no	DM-LS
GCA+stool	GM-CSF	GCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-LS
GCA+stool	GM-CSF	GCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-LS
GCA+stool	GM-CSF	GCA+stool+nutriCA+stool+CA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-LS
GCA+stool	GM-CSF	GCA+stool+GCDCA+stool+CA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-LS
GCA+stool	GM-CSF	GCA+stool+nutriCA+stool-n3+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-LS
GCA+stool	GM-CSF	GCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-LS
GCA+stool	GM-CSF	GCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-LS
GCA+stool	GM-CSF	GCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-LS
GCA+stool	GM-CSF	GCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-LS
GCA+stool	GM-CSF	GCA+stool+GCDCA+stool-Creatinine+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-LS
GCA+stool	GM-CSF	GCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-LS
GCA+stool	GM-CSF	GCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0124	no	no	no	up	no	no	DM-LS
T-a-MCA+blood	GM-CSF	T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.478	0.0124	no	no	no	up	no	no	DM-LS
Coprococcus	GM-CSF	Coprococcus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.612	0.0124	no	no	no	up	no	no	DM-LS
Oscillospira	GM-CSF	Oscillospira-Adrenergic signaling in cardiomyocytes+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.62	0.0124	no	no	no	up	no	no	DM-LS
Oscillospira	GM-CSF	Oscillospira+Peroxisome-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.62	0.0124	no	no	no	up	no	no	DM-LS
HCA+blood	GM-CSF	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.544	0.0124	no	no	no	up	no	no	DM-LS
iso-LCA+stool	GM-CSF	iso-LCA+stool-CDCA+blood-Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.72	0.0124	no	no	no	up	no	no	DM-LS
iso-LCA+stool	GM-CSF	iso-LCA+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.72	0.0124	no	no	no	up	no	no	DM-LS
iso-LCA+stool	GM-CSF	iso-LCA+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.72	0.0124	no	no	no	up	no	no	DM-LS
iso-LCA+stool	GM-CSF	iso-LCA+stool-18:3n6+blood-20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.72	0.0124	no	no	no	up	no	no	DM-LS
iso-LCA+stool	GM-CSF	iso-LCA+stool-nutriCA+stool+CA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.72	0.0124	no	no	no	up	no	no	DM-LS
iso-LCA+stool	GM-CSF	iso-LCA+stool-18:3n6+blood-UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.72	0.0124	no	no	no	up	no	no	DM-LS
iso-LCA+stool	GM-CSF	iso-LCA+stool-Glycine+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.72	0.0124	no	no	no	up	no	no	DM-LS
iso-LCA+stool	GM-CSF	iso-LCA+stool-nutriCA+stool-n3+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.72	0.0124	no	no	no	up	no	no	DM-LS
iso-LCA+stool	GM-CSF	iso-LCA+stool-18:1-LPE+blood-n3+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.72	0.0124	no	no	no	up	no	no	DM-LS
iso-LCA+stool	GM-CSF	iso-LCA+stool-Sarcosine+blood-TUDCA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.72	0.0124	no	no	no	up	no	no	DM-LS
iso-LCA+stool	GM-CSF	iso-LCA+stool-18:1-LPE+blood-22:6n3+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.72	0.0124	no	no	no	up	no	no	DM-LS
iso-LCA+stool	GM-CSF	iso-LCA+stool-CDCA+blood-MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.72	0.0124	no	no	no	up	no	no	DM-LS
iso-LCA+stool	GM-CSF	iso-LCA+stool-Glycine+blood+MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.72	0.0124	no	no	no	up	no	no	DM-LS
iso-LCA+stool	GM-CSF	iso-LCA+stool+LCA+stool-ACA+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.72	0.0124	no	no	no	up	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	GM-CSF	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.262	0.0124	no	no	no	up	no	no	DM-LS
DCA+blood	GM-CSF	DCA+blood-MUFA%+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.122	0.0124	no	no	no	up	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	GM-CSF	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0124	no	no	no	up	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	GM-CSF	3-(3-Hydroxyphenyl)propanoic acid+stool-T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0124	no	no	no	up	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	GM-CSF	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0124	no	no	no	up	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	GM-CSF	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood-UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0124	no	no	no	up	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	GM-CSF	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2/16:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0124	no	no	no	up	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	GM-CSF	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0124	no	no	no	up	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	GM-CSF	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood-MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0124	no	no	no	up	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	GM-CSF	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0124	no	no	no	up	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	GM-CSF	3-(3-Hydroxyphenyl)propanoic acid+stool+UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0124	no	no	no	up	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	GM-CSF	3-(3-Hydroxyphenyl)propanoic acid+stool-16:0/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0124	no	no	no	up	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	GM-CSF	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0124	no	no	no	up	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	GM-CSF	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0124	no	no	no	up	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	GM-CSF	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2n6c+blood+20:2+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0124	no	no	no	up	no	no	DM-LS
Indole-3-Acetic acid+stool	GM-CSF	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0124	no	no	no	up	no	no	DM-LS
Indole-3-Acetic acid+stool	GM-CSF	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0124	no	no	no	up	no	no	DM-LS
Indole-3-Acetic acid+stool	GM-CSF	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0124	no	no	no	up	no	no	DM-LS
Indole-3-Acetic acid+stool	GM-CSF	Indole-3-Acetic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0124	no	no	no	up	no	no	DM-LS
Indole-3-Acetic acid+stool	GM-CSF	Indole-3-Acetic acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0124	no	no	no	up	no	no	DM-LS
Indole-3-Acetic acid+stool	GM-CSF	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0124	no	no	no	up	no	no	DM-LS
TCA+stool	GM-CSF	TCA+stool-16:0/20:5-PC+blood+n3+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-LS
TCA+stool	GM-CSF	TCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-LS
TCA+stool	GM-CSF	TCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-LS
TCA+stool	GM-CSF	TCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-LS
TCA+stool	GM-CSF	TCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-LS
TCA+stool	GM-CSF	TCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-LS
TCA+stool	GM-CSF	TCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-LS
TCA+stool	GM-CSF	TCA+stool-16:0/20:5-PC+blood-MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-LS
TCA+stool	GM-CSF	TCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-LS
TCA+stool	GM-CSF	TCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-LS
TCA+stool	GM-CSF	TCA+stool+18:1/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-LS
TCA+stool	GM-CSF	TCA+stool+16:0/20:3-PC+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-LS
TCA+stool	GM-CSF	TCA+stool-16:0/20:5-PC+blood-20:2+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-LS
TCA+stool	GM-CSF	TCA+stool+18:1/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-LS
TCA+stool	GM-CSF	TCA+stool+16:0/20:3-PC+blood+20:2+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-LS
TCA+stool	GM-CSF	TCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-LS
TCA+stool	GM-CSF	TCA+stool-16:0/20:5-PC+blood+CA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.458	0.0124	no	no	no	up	no	no	DM-LS
HDCA+stool	GM-CSF	HDCA+stool-18:1/20:3-PC+blood-CA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.176	0.0124	no	no	no	up	no	no	DM-LS
HDCA+stool	GM-CSF	HDCA+stool-nutriCA+stool+CA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.176	0.0124	no	no	no	up	no	no	DM-LS
HDCA+stool	GM-CSF	HDCA+stool+LCA+stool-ACA+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.176	0.0124	no	no	no	up	no	no	DM-LS
HDCA+stool	GM-CSF	HDCA+stool-18:1-LPE+blood-22:6n3+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.176	0.0124	no	no	no	up	no	no	DM-LS
HDCA+stool	GM-CSF	HDCA+stool-18:1/20:3-PC+blood+20:2+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.176	0.0124	no	no	no	up	no	no	DM-LS
HDCA+stool	GM-CSF	HDCA+stool-18:1-LPC+blood+20:2+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.176	0.0124	no	no	no	up	no	no	DM-LS
HDCA+stool	GM-CSF	HDCA+stool-16:0/20:3-PC+blood+20:2+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.176	0.0124	no	no	no	up	no	no	DM-LS
HDCA+stool	GM-CSF	HDCA+stool-18:1/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.176	0.0124	no	no	no	up	no	no	DM-LS
HDCA+stool	GM-CSF	HDCA+stool+EPA+blood+n3+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.176	0.0124	no	no	no	up	no	no	DM-LS
HDCA+stool	GM-CSF	HDCA+stool-nutriCA+stool-n3+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.176	0.0124	no	no	no	up	no	no	DM-LS
HDCA+stool	GM-CSF	HDCA+stool-18:1-LPE+blood-n3+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.176	0.0124	no	no	no	up	no	no	DM-LS
HDCA+stool	GM-CSF	HDCA+stool-16:0/20:3-PC+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.176	0.0124	no	no	no	up	no	no	DM-LS
HDCA+stool	GM-CSF	HDCA+stool-18:1/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.176	0.0124	no	no	no	up	no	no	DM-LS
Lachnospira	GM-CSF	Lachnospira+Choline+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.279	0.0124	no	no	no	up	no	no	DM-LS
Fusobacterium	GM-CSF	Fusobacterium+UFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.628	0.0124	no	no	no	up	no	no	DM-LS
Fusobacterium	GM-CSF	Fusobacterium+MUFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.628	0.0124	no	no	no	up	no	no	DM-LS
isobutyric acid C4+blood	GM-CSF	isobutyric acid C4+blood+MUFA%+blood-Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.0151	0.0124	up	up	no	up	no	no	DM-LS
GCDCA+stool	GM-CSF	GCDCA+stool-Creatinine+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0124	no	dn	no	up	no	no	DM-LS
GCDCA+stool	GM-CSF	GCDCA+stool+CA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0124	no	dn	no	up	no	no	DM-LS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-LS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-LS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-LS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool-Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-LS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool-Propionic acid+stool-ACA+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-LS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-LS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool-Propionic acid+stool-MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-LS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool-Propionic acid+stool-UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-LS
5-Hydroxytryptamine+stool	GM-CSF	5-Hydroxytryptamine+stool-Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0124	dn	dn	no	up	no	no	DM-LS
Odoribacter	GM-CSF	Odoribacter+Choline+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.798	0.0124	no	no	no	up	no	no	DM-LS
Isobutyric acid+stool	GM-CSF	Isobutyric acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.408	0.0124	no	no	no	up	no	no	DM-LS
Isobutyric acid+stool	GM-CSF	Isobutyric acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.408	0.0124	no	no	no	up	no	no	DM-LS
Isobutyric acid+stool	GM-CSF	Isobutyric acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.408	0.0124	no	no	no	up	no	no	DM-LS
Isobutyric acid+stool	GM-CSF	Isobutyric acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.408	0.0124	no	no	no	up	no	no	DM-LS
Isobutyric acid+stool	GM-CSF	Isobutyric acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.408	0.0124	no	no	no	up	no	no	DM-LS
Isobutyric acid+stool	GM-CSF	Isobutyric acid+stool-nutriCA+stool+CA+blood+Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.408	0.0124	no	no	no	up	no	no	DM-LS
Isobutyric acid+stool	GM-CSF	Isobutyric acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.408	0.0124	no	no	no	up	no	no	DM-LS
Isobutyric acid+stool	GM-CSF	Isobutyric acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.408	0.0124	no	no	no	up	no	no	DM-LS
Isobutyric acid+stool	GM-CSF	Isobutyric acid+stool-nutriCA+stool-n3+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.408	0.0124	no	no	no	up	no	no	DM-LS
Lachnobacterium	GM-CSF	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.867	0.0124	no	no	no	up	no	no	DM-LS
Kynurenic acid+stool	GM-CSF	Kynurenic acid+stool-nutriCA+stool+CA+blood+Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0124	dn	dn	no	up	no	no	DM-LS
Kynurenic acid+stool	GM-CSF	Kynurenic acid+stool-nutriCA+stool-n3+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0124	dn	dn	no	up	no	no	DM-LS
Kynurenic acid+stool	GM-CSF	Kynurenic acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0124	dn	dn	no	up	no	no	DM-LS
Kynurenic acid+stool	GM-CSF	Kynurenic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0124	dn	dn	no	up	no	no	DM-LS
Anaerostipes	GM-CSF	Anaerostipes-Non-small cell lung cancer+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.568	0.0124	no	no	no	up	no	no	DM-LS
Anaerostipes	GM-CSF	Anaerostipes+TUDCA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.568	0.0124	no	no	no	up	no	no	DM-LS
TUDCA+stool	GM-CSF	TUDCA+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.241	0.0124	no	no	no	up	no	no	DM-LS
Isovaleric acid+stool	GM-CSF	Isovaleric acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.343	0.0124	no	no	no	up	no	no	DM-LS
Isovaleric acid+stool	GM-CSF	Isovaleric acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.343	0.0124	no	no	no	up	no	no	DM-LS
Isovaleric acid+stool	GM-CSF	Isovaleric acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.343	0.0124	no	no	no	up	no	no	DM-LS
Isovaleric acid+stool	GM-CSF	Isovaleric acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.343	0.0124	no	no	no	up	no	no	DM-LS
Isovaleric acid+stool	GM-CSF	Isovaleric acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.343	0.0124	no	no	no	up	no	no	DM-LS
Isovaleric acid+stool	GM-CSF	Isovaleric acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.343	0.0124	no	no	no	up	no	no	DM-LS
Isovaleric acid+stool	GM-CSF	Isovaleric acid+stool-nutriCA+stool-n3+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.343	0.0124	no	no	no	up	no	no	DM-LS
Isovaleric acid+stool	GM-CSF	Isovaleric acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.343	0.0124	no	no	no	up	no	no	DM-LS
Isovaleric acid+stool	GM-CSF	Isovaleric acid+stool-nutriCA+stool+CA+blood+Eotaxin-GM-CSF	Indirect	stool_scfa	serum_cytokines	0.343	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Arachidonic acid metabolism+Biosynthesis of amino acids-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Betaine+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Glutathione metabolism-Choline metabolism in cancer+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Arachidonic acid metabolism-Choline metabolism in cancer+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Glutathione metabolism-Cholinergic synapse+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Glutathione metabolism-mRNA surveillance pathway+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Arachidonic acid metabolism-mRNA surveillance pathway+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Glutathione metabolism-Non-small cell lung cancer+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Arachidonic acid metabolism-Non-small cell lung cancer+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+18:0/20:2-PC+blood+20:2+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Glutathione metabolism-Colorectal cancer+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Arachidonic acid metabolism-Colorectal cancer+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Arachidonic acid metabolism-Cell cycle+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Arachidonic acid metabolism+Choline+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Glutathione metabolism-ErbB signaling pathway+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Arachidonic acid metabolism-ErbB signaling pathway+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Glutathione metabolism-Phosphatidylinositol signaling system+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Arachidonic acid metabolism-Phosphatidylinositol signaling system+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella-18:0/22:6-PA+blood+22:6n3+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Glutathione metabolism-Gastric cancer+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Arachidonic acid metabolism-Gastric cancer+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Glutathione metabolism-Glioma+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Arachidonic acid metabolism-Glioma+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Glutathione metabolism-Signaling pathways regulating pluripotency of stem cells+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Arachidonic acid metabolism-Signaling pathways regulating pluripotency of stem cells+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Glutathione metabolism-Spliceosome+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Arachidonic acid metabolism-Spliceosome+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Betaine+blood-CA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Glutathione metabolism-Long-term potentiation+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
Paraprevotella	GM-CSF	Paraprevotella+Arachidonic acid metabolism-Long-term potentiation+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.118	0.0124	no	no	no	up	no	no	DM-LS
iso-LCA+blood	GM-CSF	iso-LCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.507	0.0124	no	no	no	up	no	no	DM-LS
Phenylacetic acid+stool	GM-CSF	Phenylacetic acid+stool+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0124	no	no	no	up	no	no	DM-LS
Gemmiger	GM-CSF	Gemmiger-18:1-LPC+blood+20:2+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-LS
Gemmiger	GM-CSF	Gemmiger+L-Phenylalanine+blood+n3+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.595	0.0124	no	no	no	up	no	no	DM-LS
GDCA+stool	GM-CSF	GDCA+stool-L-Phenylalanine+blood+n3+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-LS
GDCA+stool	GM-CSF	GDCA+stool-L-Isoleucine+blood+n3+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-LS
GDCA+stool	GM-CSF	GDCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-LS
GDCA+stool	GM-CSF	GDCA+stool-L-Histidine+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-LS
GDCA+stool	GM-CSF	GDCA+stool+20:3/18:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-LS
GDCA+stool	GM-CSF	GDCA+stool-L-Isoleucine+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-LS
GDCA+stool	GM-CSF	GDCA+stool+Glycine+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-LS
GDCA+stool	GM-CSF	GDCA+stool+24:1+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-LS
GDCA+stool	GM-CSF	GDCA+stool-Propionic acid+stool-UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-LS
GDCA+stool	GM-CSF	GDCA+stool-L-Histidine+blood+MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-LS
GDCA+stool	GM-CSF	GDCA+stool+Glycine+blood+MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-LS
GDCA+stool	GM-CSF	GDCA+stool-Propionic acid+stool-MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-LS
GDCA+stool	GM-CSF	GDCA+stool+20:3/18:0-PC+blood+ACA+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-LS
GDCA+stool	GM-CSF	GDCA+stool+24:1+blood+ACA+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-LS
GDCA+stool	GM-CSF	GDCA+stool-Propionic acid+stool-ACA+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-LS
GDCA+stool	GM-CSF	GDCA+stool+20:3/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.656	0.0124	no	no	no	up	no	no	DM-LS
Methanobrevibacter	GM-CSF	Methanobrevibacter+n3+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.629	0.0124	no	no	no	up	no	no	DM-LS
L-Tyrosine+stool	GM-CSF	L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0124	no	no	no	up	no	no	DM-LS
CDCA+stool	GM-CSF	CDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.663	0.0124	no	no	no	up	no	no	DM-LS
CA+stool	GM-CSF	CA+stool+CA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.827	0.0124	no	no	no	up	no	no	DM-LS
Slackia	GM-CSF	Slackia+Platinum drug resistance+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.94	0.0124	no	no	no	up	no	no	DM-LS
Slackia	GM-CSF	Slackia-Neutrophil extracellular trap formation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.94	0.0124	no	no	no	up	no	no	DM-LS
Slackia	GM-CSF	Slackia-Cysteine+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.94	0.0124	no	no	no	up	no	no	DM-LS
HDCA+blood	GM-CSF	HDCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.483	0.0124	no	no	no	up	no	no	DM-LS
UDCA+stool	GM-CSF	UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.266	0.0124	no	no	no	up	no	no	DM-LS
TDCA+stool	GM-CSF	TDCA+stool+UDCA+stool-20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.963	0.0124	no	no	no	up	no	no	DM-LS
nutriCA+stool	GM-CSF	nutriCA+stool+CA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.481	0.0124	no	no	no	up	no	no	DM-LS
nutriCA+stool	GM-CSF	nutriCA+stool-n3+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.481	0.0124	no	no	no	up	no	no	DM-LS
GDCA+blood	GM-CSF	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.632	0.0124	no	no	no	up	no	no	DM-LS
acetic acid C2+blood	GM-CSF	acetic acid C2+blood+total_blood_scfa+blood+TUDCA+blood+Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.000193	0.0124	up	dn	no	up	no	no	DM-LS
acetic acid C2+blood	GM-CSF	acetic acid C2+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.000193	0.0124	up	dn	no	up	no	no	DM-LS
acetic acid C2+blood	GM-CSF	acetic acid C2+blood+capric acid C6+blood+TUDCA+blood+Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.000193	0.0124	up	dn	no	up	no	no	DM-LS
acetic acid C2+blood	GM-CSF	acetic acid C2+blood+capric acid C6+blood+MUFA%+blood-Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.000193	0.0124	up	dn	no	up	no	no	DM-LS
acetic acid C2+blood	GM-CSF	acetic acid C2+blood-d18:1-14:1-SM+blood-MUFA%+blood-Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.000193	0.0124	up	dn	no	up	no	no	DM-LS
acetic acid C2+blood	GM-CSF	acetic acid C2+blood+capric acid C6+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.000193	0.0124	up	dn	no	up	no	no	DM-LS
acetic acid C2+blood	GM-CSF	acetic acid C2+blood-d18:1-14:1-SM+blood-UFA%+blood-Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.000193	0.0124	up	dn	no	up	no	no	DM-LS
isovaleric acid iso-C5+blood	GM-CSF	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-GM-CSF	Indirect	serum_scfa	serum_cytokines	0.117	0.0124	no	no	no	up	no	no	DM-LS
Adlercreutzia	GM-CSF	Adlercreutzia-16:0/20:5-PC+blood-20:2+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.548	0.0124	no	no	no	up	no	no	DM-LS
Adlercreutzia	GM-CSF	Adlercreutzia+18:1-LPC+blood+20:2+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.548	0.0124	no	no	no	up	no	no	DM-LS
Adlercreutzia	GM-CSF	Adlercreutzia-EPA+blood+n3+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.548	0.0124	no	no	no	up	no	no	DM-LS
Adlercreutzia	GM-CSF	Adlercreutzia-16:0/20:5-PC+blood+n3+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.548	0.0124	no	no	no	up	no	no	DM-LS
Adlercreutzia	GM-CSF	Adlercreutzia-16:0/20:5-PC+blood+CA+blood+Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.548	0.0124	no	no	no	up	no	no	DM-LS
Adlercreutzia	GM-CSF	Adlercreutzia-16:0/20:5-PC+blood-MUFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.548	0.0124	no	no	no	up	no	no	DM-LS
Adlercreutzia	GM-CSF	Adlercreutzia+16:0/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.548	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium+cGMP-PKG signaling pathway+Lipid and atherosclerosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium+cGMP-PKG signaling pathway+Endocytosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium+cGMP-PKG signaling pathway+IL-17 signaling pathway-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium+PUFA/MUFA+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium-14:0/20:4-PC+blood-UFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium-Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
 Clostridium	GM-CSF	Clostridium+Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	NA	0.0124	NA	NA	NA	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium-Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
 Clostridium	GM-CSF	Clostridium+Acetic acid+stool-UFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	NA	0.0124	NA	NA	NA	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium+cGMP-PKG signaling pathway+Fc gamma R-mediated phagocytosis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium+cGMP-PKG signaling pathway+Neutrophil extracellular trap formation-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium+cGMP-PKG signaling pathway+Pathogenic Escherichia coli infection-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium-18:0/20:2-PC+blood+20:2+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium+CDCA+blood-Cysteine+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium-14:0/20:4-PC+blood-Cysteine+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium-Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
 Clostridium	GM-CSF	Clostridium+Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	NA	0.0124	NA	NA	NA	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium-Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
 Clostridium	GM-CSF	Clostridium+Acetic acid+stool-Cysteine+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	NA	0.0124	NA	NA	NA	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium-14:0/20:4-PC+blood-Creatinine+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium-14:0/18:2-PC+blood-Creatinine+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium-14:0/20:4-PC+blood-20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium+CDCA+blood-MUFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium-14:0/20:4-PC+blood-MUFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium+cGMP-PKG signaling pathway+MUFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
Clostridium	GM-CSF	Clostridium-14:0/18:2-PC+blood-MUFA%+blood-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.925	0.0124	no	no	no	up	no	no	DM-LS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+n3+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-LS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-LS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-LS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-LS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-LS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-LS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-LS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood-MUFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-LS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-LS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-LS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-LS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-LS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood-20:2+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-LS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-LS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+20:2+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-LS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-TCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-LS
T-¦Á-MCA+stool	GM-CSF	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+CA+blood+Eotaxin-GM-CSF	Indirect	stool_bileacids	serum_cytokines	0.48	0.0124	no	no	no	up	no	no	DM-LS
12-ketoDCA+blood	GM-CSF	12-ketoDCA+blood-8-HETE+blood-ACA+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.517	0.0124	no	no	no	up	no	no	DM-LS
12-ketoDCA+blood	GM-CSF	12-ketoDCA+blood-20:3-LPE+blood-22:6n3+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.517	0.0124	no	no	no	up	no	no	DM-LS
12-ketoDCA+blood	GM-CSF	12-ketoDCA+blood-20:3-LPE+blood+Choline+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.517	0.0124	no	no	no	up	no	no	DM-LS
12-ketoDCA+blood	GM-CSF	12-ketoDCA+blood-L-Lysine+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.517	0.0124	no	no	no	up	no	no	DM-LS
12-ketoDCA+blood	GM-CSF	12-ketoDCA+blood-L-Arginine+blood+UFA%+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.517	0.0124	no	no	no	up	no	no	DM-LS
12-ketoDCA+blood	GM-CSF	12-ketoDCA+blood-20:3-LPE+blood-n3+blood-Eotaxin-GM-CSF	Indirect	serum_bileacids	serum_cytokines	0.517	0.0124	no	no	no	up	no	no	DM-LS
Butyricicoccus	GM-CSF	Butyricicoccus+Allograft rejection-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.852	0.0124	no	no	no	up	no	no	DM-LS
Butyricicoccus	GM-CSF	Butyricicoccus+Viral myocarditis-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.852	0.0124	no	no	no	up	no	no	DM-LS
Butyricicoccus	GM-CSF	Butyricicoccus+Cell adhesion molecules-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.852	0.0124	no	no	no	up	no	no	DM-LS
Butyricicoccus	GM-CSF	Butyricicoccus+Type I diabetes mellitus-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.852	0.0124	no	no	no	up	no	no	DM-LS
Butyricicoccus	GM-CSF	Butyricicoccus+Graft-versus-host disease-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.852	0.0124	no	no	no	up	no	no	DM-LS
Butyricicoccus	GM-CSF	Butyricicoccus+Phagosome-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.852	0.0124	no	no	no	up	no	no	DM-LS
Butyricicoccus	GM-CSF	Butyricicoccus+Autoimmune thyroid disease-Eotaxin-GM-CSF	Indirect	Genus	serum_cytokines	0.852	0.0124	no	no	no	up	no	no	DM-LS
Blautia	MIP-1a	Blautia-20:5/18:0-PC+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	1.36E-05	0.68	up	dn	dn	no	no	no	DM-LS
Parabacteroides	MIP-1a	Parabacteroides-Glucagon signaling pathway+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	4.19E-05	0.68	no	up	up	no	no	no	DM-LS
Parabacteroides	MIP-1a	Parabacteroides-Spliceosome+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	4.19E-05	0.68	no	up	up	no	no	no	DM-LS
Parabacteroides	MIP-1a	Parabacteroides+Choline+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	4.19E-05	0.68	no	up	up	no	no	no	DM-LS
Dorea	MIP-1a	Dorea-Lipid and atherosclerosis-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.00362	0.68	up	no	dn	no	no	no	DM-LS
Dorea	MIP-1a	Dorea-18:0/22:6-PE+blood+IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.00362	0.68	up	no	dn	no	no	no	DM-LS
Faecalibacterium	MIP-1a	Faecalibacterium-Cysteine+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.0039	0.68	no	dn	dn	no	no	no	DM-LS
Faecalibacterium	MIP-1a	Faecalibacterium-Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.0039	0.68	no	dn	dn	no	no	no	DM-LS
TUDCA+blood	MIP-1a	TUDCA+blood+Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.0282	0.68	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	MIP-1a	isocapric acid iso-C6+blood-n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.0458	0.68	no	no	dn	no	no	no	DM-LS
Bacteroides	MIP-1a	Bacteroides+n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-LS
Bacteroides	MIP-1a	Bacteroides+22:6n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.000267	0.68	dn	dn	up	no	no	no	DM-LS
Propionic acid+stool	MIP-1a	Propionic acid+stool+18:0/22:6-PE+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_scfa	serum_cytokines	0.0436	0.68	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	MIP-1a	Propionic acid+stool+16:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_scfa	serum_cytokines	0.0436	0.68	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	MIP-1a	Propionic acid+stool-UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_scfa	serum_cytokines	0.0436	0.68	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	MIP-1a	Propionic acid+stool-MUFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_scfa	serum_cytokines	0.0436	0.68	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	MIP-1a	Propionic acid+stool-ACA+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_scfa	serum_cytokines	0.0436	0.68	dn	no	up	no	no	no	DM-LS
[Ruminococcus]	MIP-1a	[Ruminococcus]-UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.0679	0.68	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	MIP-1a	[Ruminococcus]-20:5/18:0-PC+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.0679	0.68	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	MIP-1a	[Ruminococcus]-MUFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.0679	0.68	no	no	dn	no	no	no	DM-LS
[Ruminococcus]	MIP-1a	[Ruminococcus]-FGF basic+IL-17A-IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.0679	0.68	no	no	dn	no	no	no	DM-LS
GUDCA+blood	MIP-1a	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.0766	0.68	no	no	dn	no	no	no	DM-LS
Acetic acid+stool	MIP-1a	Acetic acid+stool-Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_scfa	serum_cytokines	0.0656	0.68	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	MIP-1a	Acetic acid+stool-UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_scfa	serum_cytokines	0.0656	0.68	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	MIP-1a	Acetic acid+stool-Cysteine+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_scfa	serum_cytokines	0.0656	0.68	dn	no	no	no	no	no	DM-LS
Alistipes	MIP-1a	Alistipes+12-ketoDCA+stool+18:0/22:6-PE+blood+IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.0114	0.68	no	up	no	no	no	no	DM-LS
Alistipes	MIP-1a	Alistipes-L-Arginine+blood+UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.0114	0.68	no	up	no	no	no	no	DM-LS
Alistipes	MIP-1a	Alistipes-HIF-1 signaling pathway+Measles-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.0114	0.68	no	up	no	no	no	no	DM-LS
Alistipes	MIP-1a	Alistipes-L-Aspartic acid+blood+n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.0114	0.68	no	up	no	no	no	no	DM-LS
Butyricimonas	MIP-1a	Butyricimonas+20:5/18:0-PC+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.17	0.68	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1a	Collinsella-Signaling pathways regulating pluripotency of stem cells+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.128	0.68	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1a	Collinsella-Colorectal cancer+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.128	0.68	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1a	Collinsella-Glioma+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.128	0.68	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1a	Collinsella-Long-term potentiation+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.128	0.68	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1a	Collinsella-Choline metabolism in cancer+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.128	0.68	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1a	Collinsella-Gastric cancer+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.128	0.68	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1a	Collinsella-ErbB signaling pathway+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.128	0.68	no	no	no	no	no	no	DM-LS
Collinsella	MIP-1a	Collinsella-Phosphatidylinositol signaling system+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.128	0.68	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	MIP-1a	total_blood_scfa+blood+TUDCA+blood+Eotaxin-IL-6-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.168	0.68	no	no	no	no	no	no	DM-LS
[Eubacterium]	MIP-1a	[Eubacterium]-Viral myocarditis-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.0692	0.68	no	no	no	no	no	no	DM-LS
[Eubacterium]	MIP-1a	[Eubacterium]-Pathogenic Escherichia coli infection-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.0692	0.68	no	no	no	no	no	no	DM-LS
[Eubacterium]	MIP-1a	[Eubacterium]-Phagosome-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.0692	0.68	no	no	no	no	no	no	DM-LS
LCA+stool	MIP-1a	LCA+stool-ACA+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.314	0.68	no	no	no	no	no	no	DM-LS
Akkermansia	MIP-1a	Akkermansia+18:0/22:6-PE+blood+IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.23	0.68	no	no	no	no	no	no	DM-LS
Bifidobacterium	MIP-1a	Bifidobacterium-FGF basic+IL-17A-IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.105	0.68	no	dn	no	no	no	no	DM-LS
Bifidobacterium	MIP-1a	Bifidobacterium+Chemical carcinogenesis - receptor activation+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.105	0.68	no	dn	no	no	no	no	DM-LS
Ruminococcus	MIP-1a	Ruminococcus+Type I diabetes mellitus-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.335	0.68	no	no	no	no	no	no	DM-LS
Ruminococcus	MIP-1a	Ruminococcus+Endocytosis-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.335	0.68	no	no	no	no	no	no	DM-LS
Ruminococcus	MIP-1a	Ruminococcus+Allograft rejection-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.335	0.68	no	no	no	no	no	no	DM-LS
Ruminococcus	MIP-1a	Ruminococcus+22:6n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.335	0.68	no	no	no	no	no	no	DM-LS
Ruminococcus	MIP-1a	Ruminococcus+Graft-versus-host disease-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.335	0.68	no	no	no	no	no	no	DM-LS
Ruminococcus	MIP-1a	Ruminococcus+Phagosome-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.335	0.68	no	no	no	no	no	no	DM-LS
Ruminococcus	MIP-1a	Ruminococcus+Cell adhesion molecules-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.335	0.68	no	no	no	no	no	no	DM-LS
Ruminococcus	MIP-1a	Ruminococcus+Autoimmune thyroid disease-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.335	0.68	no	no	no	no	no	no	DM-LS
GCDCA+blood	MIP-1a	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.31	0.68	no	no	no	no	no	no	DM-LS
Succinivibrio	MIP-1a	Succinivibrio-L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.138	0.68	no	no	no	no	no	no	DM-LS
Succinivibrio	MIP-1a	Succinivibrio-L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.138	0.68	no	no	no	no	no	no	DM-LS
Succinivibrio	MIP-1a	Succinivibrio-L-Phenylalanine+stool+n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.138	0.68	no	no	no	no	no	no	DM-LS
Succinivibrio	MIP-1a	Succinivibrio-Phospholipase D signaling pathway+Cushing syndrome+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.138	0.68	no	no	no	no	no	no	DM-LS
Succinivibrio	MIP-1a	Succinivibrio-Phospholipase D signaling pathway-MUFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.138	0.68	no	no	no	no	no	no	DM-LS
Succinivibrio	MIP-1a	Succinivibrio-L-Phenylalanine+stool+Cysteine+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.138	0.68	no	no	no	no	no	no	DM-LS
Succinivibrio	MIP-1a	Succinivibrio-Phospholipase D signaling pathway+Chemical carcinogenesis - receptor activation+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.138	0.68	no	no	no	no	no	no	DM-LS
Succinivibrio	MIP-1a	Succinivibrio-L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.138	0.68	no	no	no	no	no	no	DM-LS
Succinivibrio	MIP-1a	Succinivibrio-L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.138	0.68	no	no	no	no	no	no	DM-LS
Succinivibrio	MIP-1a	Succinivibrio-Phospholipase D signaling pathway-UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.138	0.68	no	no	no	no	no	no	DM-LS
ACA+blood	MIP-1a	ACA+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.338	0.68	no	no	no	no	no	no	DM-LS
DCA+stool	MIP-1a	DCA+stool-UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.195	0.68	no	no	no	no	no	no	DM-LS
DCA+stool	MIP-1a	DCA+stool-ACA+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.195	0.68	no	no	no	no	no	no	DM-LS
Butyric acid+stool	MIP-1a	Butyric acid+stool-Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_scfa	serum_cytokines	0.102	0.68	dn	no	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	MIP-1a	4-hydroxybenzoic acid+stool-Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.68	no	dn	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	MIP-1a	4-hydroxybenzoic acid+stool+ACA+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.68	no	dn	no	no	no	no	DM-LS
GCA+blood	MIP-1a	GCA+blood+FGF basic+IL-17A-IL-8-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.16	0.68	no	no	no	no	no	no	DM-LS
ACA+stool	MIP-1a	ACA+stool+20:5/18:0-PC+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.417	0.68	no	no	no	no	no	no	DM-LS
ACA+stool	MIP-1a	ACA+stool+20:2+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.417	0.68	no	no	no	no	no	no	DM-LS
ACA+stool	MIP-1a	ACA+stool+GPC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.417	0.68	no	no	no	no	no	no	DM-LS
CDCA+blood	MIP-1a	CDCA+blood-MUFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.506	0.68	no	no	no	no	no	no	DM-LS
CDCA+blood	MIP-1a	CDCA+blood-Cysteine+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.506	0.68	no	no	no	no	no	no	DM-LS
capric acid C6+blood	MIP-1a	capric acid C6+blood+UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.433	0.68	no	no	no	no	no	no	DM-LS
capric acid C6+blood	MIP-1a	capric acid C6+blood+TUDCA+blood+Eotaxin-IL-6-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.433	0.68	no	no	no	no	no	no	DM-LS
capric acid C6+blood	MIP-1a	capric acid C6+blood+MUFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.433	0.68	no	no	no	no	no	no	DM-LS
Pyramidobacter	MIP-1a	Pyramidobacter-Carbon metabolism-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.45	0.68	no	no	no	no	no	no	DM-LS
Pyramidobacter	MIP-1a	Pyramidobacter+Glucagon signaling pathway+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.45	0.68	no	no	no	no	no	no	DM-LS
Prevotella	MIP-1a	Prevotella-Proteasome-IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.287	0.68	no	no	no	no	no	no	DM-LS
Prevotella	MIP-1a	Prevotella+Aldosterone synthesis and secretion+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.287	0.68	no	no	no	no	no	no	DM-LS
Prevotella	MIP-1a	Prevotella+Adrenergic signaling in cardiomyocytes+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.287	0.68	no	no	no	no	no	no	DM-LS
Prevotella	MIP-1a	Prevotella+Chemical carcinogenesis - receptor activation+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.287	0.68	no	no	no	no	no	no	DM-LS
Prevotella	MIP-1a	Prevotella+Inflammatory mediator regulation of TRP channels+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.287	0.68	no	no	no	no	no	no	DM-LS
Prevotella	MIP-1a	Prevotella-Carbon metabolism-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.287	0.68	no	no	no	no	no	no	DM-LS
Prevotella	MIP-1a	Prevotella+Amphetamine addiction+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.287	0.68	no	no	no	no	no	no	DM-LS
Prevotella	MIP-1a	Prevotella+Dopaminergic synapse+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.287	0.68	no	no	no	no	no	no	DM-LS
Prevotella	MIP-1a	Prevotella+Cushing syndrome+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.287	0.68	no	no	no	no	no	no	DM-LS
Prevotella	MIP-1a	Prevotella+Melanogenesis+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.287	0.68	no	no	no	no	no	no	DM-LS
TCA+blood	MIP-1a	TCA+blood+FGF basic+IL-17A-IL-8-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.339	0.68	no	no	no	no	no	no	DM-LS
TCA+blood	MIP-1a	TCA+blood+TUDCA+blood+Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.339	0.68	no	no	no	no	no	no	DM-LS
iso-DCA+blood	MIP-1a	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.38	0.68	no	no	no	no	no	no	DM-LS
iso-DCA+blood	MIP-1a	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.38	0.68	no	no	no	no	no	no	DM-LS
iso-DCA+blood	MIP-1a	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.38	0.68	no	no	no	no	no	no	DM-LS
HCA+stool	MIP-1a	HCA+stool-Cysteine+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.155	0.68	no	no	no	no	no	no	DM-LS
HCA+stool	MIP-1a	HCA+stool-18:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.155	0.68	no	no	no	no	no	no	DM-LS
HCA+stool	MIP-1a	HCA+stool-GPC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.155	0.68	no	no	no	no	no	no	DM-LS
Roseburia	MIP-1a	Roseburia-20:1+blood-IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.495	0.68	no	no	no	no	no	no	DM-LS
Roseburia	MIP-1a	Roseburia-20:2+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.495	0.68	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	MIP-1a	12-ketoDCA+stool+18:0/22:6-PE+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.505	0.68	no	no	no	no	no	no	DM-LS
GLCA+blood	MIP-1a	GLCA+blood-Sarcosine+blood-FGF basic+IL-17A-IL-8-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.319	0.68	no	no	no	no	no	no	DM-LS
GLCA+blood	MIP-1a	GLCA+blood-PUFA/MUFA+blood+UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.319	0.68	no	no	no	no	no	no	DM-LS
GLCA+blood	MIP-1a	GLCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.319	0.68	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	MIP-1a	L-Tryptophan+stool+n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.557	0.68	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	MIP-1a	L-Tryptophan+stool+Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.557	0.68	no	no	no	no	no	no	DM-LS
CA+blood	MIP-1a	CA+blood+Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.606	0.68	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	MIP-1a	L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.398	0.68	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	MIP-1a	L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.398	0.68	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	MIP-1a	L-Phenylalanine+stool+n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.398	0.68	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	MIP-1a	L-Phenylalanine+stool+Cysteine+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.398	0.68	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	MIP-1a	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.407	0.68	no	no	no	no	no	no	DM-LS
GCA+stool	MIP-1a	GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.0809	0.68	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	MIP-1a	T-a-MCA+blood+UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.478	0.68	no	no	no	no	no	no	DM-LS
Coprococcus	MIP-1a	Coprococcus-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.612	0.68	no	no	no	no	no	no	DM-LS
Oscillospira	MIP-1a	Oscillospira-Adrenergic signaling in cardiomyocytes+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-LS
Oscillospira	MIP-1a	Oscillospira+Peroxisome-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.62	0.68	no	no	no	no	no	no	DM-LS
HCA+blood	MIP-1a	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.544	0.68	no	no	no	no	no	no	DM-LS
iso-LCA+stool	MIP-1a	iso-LCA+stool+Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.72	0.68	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	MIP-1a	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin-IL-6-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.262	0.68	no	no	no	no	no	no	DM-LS
DCA+blood	MIP-1a	DCA+blood-MUFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.122	0.68	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1a	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.33	0.68	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1a	3-(3-Hydroxyphenyl)propanoic acid+stool-20:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.33	0.68	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	MIP-1a	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.68	no	no	no	no	no	no	DM-LS
TCA+stool	MIP-1a	TCA+stool-16:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.458	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool-18:1/20:3-PC+blood-CA+blood+Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool-nutriCA+stool+CA+blood+Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool+LCA+stool-ACA+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool-18:1-LPE+blood-22:6n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool-18:1/20:3-PC+blood+20:2+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool-18:1-LPC+blood+20:2+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool-16:0/20:3-PC+blood+20:2+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool-18:1/18:1-PC+blood+20:2+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool+EPA+blood+n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool-nutriCA+stool-n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool-18:1-LPE+blood-n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool-16:0/20:3-PC+blood+UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool-18:1/18:1-PC+blood+UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool-18:1/20:3-PC+blood+20:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool-16:0-LPC+blood+GPC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool-nutriCA+stool-Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool+iso-LCA+stool+Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool-16:0/20:3-PC+blood-16:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool-16:0-LPC+blood-18:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
HDCA+stool	MIP-1a	HDCA+stool-18:0-LPA+blood-18:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.176	0.68	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1a	Lachnospira+Choline+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1a	Lachnospira+18:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-LS
Lachnospira	MIP-1a	Lachnospira+20:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.279	0.68	no	no	no	no	no	no	DM-LS
Fusobacterium	MIP-1a	Fusobacterium+UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.628	0.68	no	no	no	no	no	no	DM-LS
Fusobacterium	MIP-1a	Fusobacterium+MUFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.628	0.68	no	no	no	no	no	no	DM-LS
isobutyric acid C4+blood	MIP-1a	isobutyric acid C4+blood+MUFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.0151	0.68	up	up	no	no	no	no	DM-LS
GCDCA+stool	MIP-1a	GCDCA+stool-Creatinine+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.68	no	dn	no	no	no	no	DM-LS
GCDCA+stool	MIP-1a	GCDCA+stool+CA+blood+Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.68	no	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-Acetic acid+stool-Cysteine+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-Propionic acid+stool-ACA+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-Propionic acid+stool-MUFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-Propionic acid+stool-UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-Acetic acid+stool-UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool+L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-Acetic acid+stool-Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool+Indole-3-Acetic acid+stool+Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	MIP-1a	5-Hydroxytryptamine+stool-Propionic acid+stool+18:0/22:6-PE+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.68	dn	dn	no	no	no	no	DM-LS
Odoribacter	MIP-1a	Odoribacter+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.798	0.68	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	MIP-1a	Isobutyric acid+stool+Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_scfa	serum_cytokines	0.408	0.68	no	no	no	no	no	no	DM-LS
Lachnobacterium	MIP-1a	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.867	0.68	no	no	no	no	no	no	DM-LS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool-nutriCA+stool-Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool+L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool-UDCA+stool-18:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool-UDCA+stool-20:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool-nutriCA+stool+CA+blood+Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool-nutriCA+stool-n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	MIP-1a	Kynurenic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.68	dn	dn	no	no	no	no	DM-LS
Anaerostipes	MIP-1a	Anaerostipes-Non-small cell lung cancer+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.568	0.68	no	no	no	no	no	no	DM-LS
Anaerostipes	MIP-1a	Anaerostipes+TUDCA+blood+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.568	0.68	no	no	no	no	no	no	DM-LS
TUDCA+stool	MIP-1a	TUDCA+stool-UDCA+stool-20:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.241	0.68	no	no	no	no	no	no	DM-LS
TUDCA+stool	MIP-1a	TUDCA+stool-UDCA+stool-18:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.241	0.68	no	no	no	no	no	no	DM-LS
TUDCA+stool	MIP-1a	TUDCA+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.241	0.68	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	MIP-1a	Isovaleric acid+stool+Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_scfa	serum_cytokines	0.343	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+18:0/20:2-PC+blood-18:0/22:6-PE+blood+IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+18:0/20:2-PC+blood+20:1+blood-IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+d18:1-20:0-SM+blood+GPC+blood+IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Arachidonic acid metabolism+Biosynthesis of amino acids-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Betaine+blood+UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Glutathione metabolism-Choline metabolism in cancer+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Arachidonic acid metabolism-Choline metabolism in cancer+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Glutathione metabolism-Cholinergic synapse+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Glutathione metabolism-mRNA surveillance pathway+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Arachidonic acid metabolism-mRNA surveillance pathway+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Glutathione metabolism-Non-small cell lung cancer+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Arachidonic acid metabolism-Non-small cell lung cancer+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+18:0/20:2-PC+blood+20:2+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Glutathione metabolism-Colorectal cancer+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Arachidonic acid metabolism-Colorectal cancer+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Arachidonic acid metabolism-Cell cycle+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Arachidonic acid metabolism+Choline+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Glutathione metabolism-ErbB signaling pathway+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Arachidonic acid metabolism-ErbB signaling pathway+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Glutathione metabolism-Phosphatidylinositol signaling system+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Arachidonic acid metabolism-Phosphatidylinositol signaling system+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella-18:0/22:6-PA+blood+22:6n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Glutathione metabolism-Gastric cancer+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Arachidonic acid metabolism-Gastric cancer+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Glutathione metabolism-Glioma+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Arachidonic acid metabolism-Glioma+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Glutathione metabolism-Signaling pathways regulating pluripotency of stem cells+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Arachidonic acid metabolism-Signaling pathways regulating pluripotency of stem cells+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Glutathione metabolism-Spliceosome+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Arachidonic acid metabolism-Spliceosome+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Betaine+blood-CA+blood+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Glutathione metabolism-Long-term potentiation+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
Paraprevotella	MIP-1a	Paraprevotella+Arachidonic acid metabolism-Long-term potentiation+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.118	0.68	no	no	no	no	no	no	DM-LS
iso-LCA+blood	MIP-1a	iso-LCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.507	0.68	no	no	no	no	no	no	DM-LS
iso-LCA+blood	MIP-1a	iso-LCA+blood-Sarcosine+blood-FGF basic+IL-17A-IL-8-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.507	0.68	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	MIP-1a	Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.785	0.68	no	no	no	no	no	no	DM-LS
Gemmiger	MIP-1a	Gemmiger-18:1-LPC+blood+20:2+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.595	0.68	no	no	no	no	no	no	DM-LS
Gemmiger	MIP-1a	Gemmiger+L-Phenylalanine+blood+n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.595	0.68	no	no	no	no	no	no	DM-LS
Gemmiger	MIP-1a	Gemmiger-GCA+stool+L-2-Aminobutyric acid+blood-IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.595	0.68	no	no	no	no	no	no	DM-LS
Gemmiger	MIP-1a	Gemmiger+DHA+blood-L-2-Aminobutyric acid+blood-IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.595	0.68	no	no	no	no	no	no	DM-LS
GDCA+stool	MIP-1a	GDCA+stool-18:0/22:6-PE+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.656	0.68	no	no	no	no	no	no	DM-LS
Methanobrevibacter	MIP-1a	Methanobrevibacter+L-2-Aminobutyric acid+blood-IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.629	0.68	no	no	no	no	no	no	DM-LS
Methanobrevibacter	MIP-1a	Methanobrevibacter+n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.629	0.68	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	MIP-1a	L-Tyrosine+stool+Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.68	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	MIP-1a	L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.68	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1a	CDCA+stool-Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.663	0.68	no	no	no	no	no	no	DM-LS
CDCA+stool	MIP-1a	CDCA+stool-20:5/18:0-PC+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.663	0.68	no	no	no	no	no	no	DM-LS
CA+stool	MIP-1a	CA+stool-Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.827	0.68	no	no	no	no	no	no	DM-LS
CA+stool	MIP-1a	CA+stool-18:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.827	0.68	no	no	no	no	no	no	DM-LS
CA+stool	MIP-1a	CA+stool-20:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.827	0.68	no	no	no	no	no	no	DM-LS
CA+stool	MIP-1a	CA+stool+CA+blood+Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.827	0.68	no	no	no	no	no	no	DM-LS
Slackia	MIP-1a	Slackia+Platinum drug resistance+Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.94	0.68	no	no	no	no	no	no	DM-LS
Slackia	MIP-1a	Slackia-Neutrophil extracellular trap formation-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.94	0.68	no	no	no	no	no	no	DM-LS
Slackia	MIP-1a	Slackia-Cysteine+blood-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.94	0.68	no	no	no	no	no	no	DM-LS
HDCA+blood	MIP-1a	HDCA+blood-Sarcosine+blood-FGF basic+IL-17A-IL-8-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.483	0.68	no	no	no	no	no	no	DM-LS
HDCA+blood	MIP-1a	HDCA+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.483	0.68	no	no	no	no	no	no	DM-LS
UDCA+stool	MIP-1a	UDCA+stool-20:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.266	0.68	no	no	no	no	no	no	DM-LS
UDCA+stool	MIP-1a	UDCA+stool-18:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.266	0.68	no	no	no	no	no	no	DM-LS
UDCA+stool	MIP-1a	UDCA+stool-20:5/18:0-PC+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.266	0.68	no	no	no	no	no	no	DM-LS
TDCA+stool	MIP-1a	TDCA+stool+UDCA+stool-20:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.963	0.68	no	no	no	no	no	no	DM-LS
TDCA+stool	MIP-1a	TDCA+stool+UDCA+stool-18:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.963	0.68	no	no	no	no	no	no	DM-LS
TDCA+stool	MIP-1a	TDCA+stool+UDCA+stool-20:5/18:0-PC+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.963	0.68	no	no	no	no	no	no	DM-LS
nutriCA+stool	MIP-1a	nutriCA+stool-Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.481	0.68	no	no	no	no	no	no	DM-LS
nutriCA+stool	MIP-1a	nutriCA+stool+CA+blood+Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.481	0.68	no	no	no	no	no	no	DM-LS
nutriCA+stool	MIP-1a	nutriCA+stool-n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.481	0.68	no	no	no	no	no	no	DM-LS
GDCA+blood	MIP-1a	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.632	0.68	no	no	no	no	no	no	DM-LS
acetic acid C2+blood	MIP-1a	acetic acid C2+blood-L-Alanine+blood-FGF basic+IL-17A-IL-8-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.000193	0.68	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	MIP-1a	acetic acid C2+blood-Sarcosine+blood-FGF basic+IL-17A-IL-8-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.000193	0.68	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	MIP-1a	acetic acid C2+blood+total_blood_scfa+blood+TUDCA+blood+Eotaxin-IL-6-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.000193	0.68	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	MIP-1a	acetic acid C2+blood-Sarcosine+blood-TUDCA+blood+Eotaxin-IL-6-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.000193	0.68	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	MIP-1a	acetic acid C2+blood+capric acid C6+blood+TUDCA+blood+Eotaxin-IL-6-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.000193	0.68	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	MIP-1a	acetic acid C2+blood+capric acid C6+blood+MUFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.000193	0.68	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	MIP-1a	acetic acid C2+blood-d18:1-14:1-SM+blood-MUFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.000193	0.68	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	MIP-1a	acetic acid C2+blood+capric acid C6+blood+UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.000193	0.68	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	MIP-1a	acetic acid C2+blood-d18:1-14:1-SM+blood-UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.000193	0.68	up	dn	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	MIP-1a	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin-IL-6-MIP-1a	Indirect	serum_scfa	serum_cytokines	0.117	0.68	no	no	no	no	no	no	DM-LS
Adlercreutzia	MIP-1a	Adlercreutzia-16:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.548	0.68	no	no	no	no	no	no	DM-LS
Clostridium	MIP-1a	Clostridium-20:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.925	0.68	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	MIP-1a	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+IL-1ra+IL-8-MIP-1a	Indirect	stool_bileacids	serum_cytokines	0.48	0.68	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	MIP-1a	12-ketoDCA+blood-8-HETE+blood-ACA+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.517	0.68	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	MIP-1a	12-ketoDCA+blood-20:3-LPE+blood-22:6n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.517	0.68	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	MIP-1a	12-ketoDCA+blood-20:3-LPE+blood+Choline+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.517	0.68	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	MIP-1a	12-ketoDCA+blood-L-Lysine+blood+UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.517	0.68	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	MIP-1a	12-ketoDCA+blood-L-Arginine+blood+UFA%+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.517	0.68	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	MIP-1a	12-ketoDCA+blood-20:3-LPE+blood-n3+blood-Eotaxin-IL-6-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.517	0.68	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	MIP-1a	12-ketoDCA+blood-20:0-LPC+blood+20:1+blood-IL-1ra+IL-8-MIP-1a	Indirect	serum_bileacids	serum_cytokines	0.517	0.68	no	no	no	no	no	no	DM-LS
Butyricicoccus	MIP-1a	Butyricicoccus+Allograft rejection-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-LS
Butyricicoccus	MIP-1a	Butyricicoccus+Viral myocarditis-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-LS
Butyricicoccus	MIP-1a	Butyricicoccus+Cell adhesion molecules-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-LS
Butyricicoccus	MIP-1a	Butyricicoccus+Type I diabetes mellitus-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-LS
Butyricicoccus	MIP-1a	Butyricicoccus+Graft-versus-host disease-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-LS
Butyricicoccus	MIP-1a	Butyricicoccus+Phagosome-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-LS
Butyricicoccus	MIP-1a	Butyricicoccus+Autoimmune thyroid disease-Eotaxin-IL-6-MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-LS
Butyricicoccus	MIP-1a	Butyricicoccus-Phenylacetic acid+stool-IL-1ra+IL-8-MIP-1a	Indirect	Genus	serum_cytokines	0.852	0.68	no	no	no	no	no	no	DM-LS
Blautia	IL-17A	Blautia+GCA+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-LS
Blautia	IL-17A	Blautia-20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	DM-LS
Parabacteroides	IL-17A	Parabacteroides+20:0+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	4.19E-05	0.855	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-17A	Parabacteroides-Glucagon signaling pathway+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	4.19E-05	0.855	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-17A	Parabacteroides-Spliceosome+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	4.19E-05	0.855	no	up	up	no	no	no	DM-LS
Parabacteroides	IL-17A	Parabacteroides+Choline+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	4.19E-05	0.855	no	up	up	no	no	no	DM-LS
Dorea	IL-17A	Dorea-Lipid and atherosclerosis-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	DM-LS
Faecalibacterium	IL-17A	Faecalibacterium-Cysteine+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.0039	0.855	no	dn	dn	no	no	no	DM-LS
TUDCA+blood	IL-17A	TUDCA+blood+Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.0282	0.855	no	no	dn	no	no	no	DM-LS
isocapric acid iso-C6+blood	IL-17A	isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-17A	Indirect	serum_scfa	serum_cytokines	0.0458	0.855	no	no	dn	no	no	no	DM-LS
Bacteroides	IL-17A	Bacteroides+n3+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.000267	0.855	dn	dn	up	no	no	no	DM-LS
Bacteroides	IL-17A	Bacteroides+22:6n3+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.000267	0.855	dn	dn	up	no	no	no	DM-LS
Propionic acid+stool	IL-17A	Propionic acid+stool-UFA%+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.0436	0.855	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IL-17A	Propionic acid+stool-MUFA%+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.0436	0.855	dn	no	up	no	no	no	DM-LS
Propionic acid+stool	IL-17A	Propionic acid+stool-ACA+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.0436	0.855	dn	no	up	no	no	no	DM-LS
[Ruminococcus]	IL-17A	[Ruminococcus]-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	DM-LS
GUDCA+blood	IL-17A	GUDCA+blood-isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.0766	0.855	no	no	dn	no	no	no	DM-LS
Acetic acid+stool	IL-17A	Acetic acid+stool-UFA%+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.0656	0.855	dn	no	no	no	no	no	DM-LS
Acetic acid+stool	IL-17A	Acetic acid+stool-Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.0656	0.855	dn	no	no	no	no	no	DM-LS
Alistipes	IL-17A	Alistipes-L-Arginine+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-LS
Alistipes	IL-17A	Alistipes-HIF-1 signaling pathway+Measles-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-LS
Alistipes	IL-17A	Alistipes-L-Aspartic acid+blood+n3+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-LS
Alistipes	IL-17A	Alistipes+12-ketoDCA+stool-L-Alanine+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	DM-LS
Butyricimonas	IL-17A	Butyricimonas-GCA+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.17	0.855	no	no	no	no	no	no	DM-LS
Butyricimonas	IL-17A	Butyricimonas+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.17	0.855	no	no	no	no	no	no	DM-LS
Collinsella	IL-17A	Collinsella-Signaling pathways regulating pluripotency of stem cells+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-LS
Collinsella	IL-17A	Collinsella-Colorectal cancer+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-LS
Collinsella	IL-17A	Collinsella-Glioma+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-LS
Collinsella	IL-17A	Collinsella-Long-term potentiation+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-LS
Collinsella	IL-17A	Collinsella-Choline metabolism in cancer+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-LS
Collinsella	IL-17A	Collinsella-Gastric cancer+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-LS
Collinsella	IL-17A	Collinsella-ErbB signaling pathway+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-LS
Collinsella	IL-17A	Collinsella-Phosphatidylinositol signaling system+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-LS
Collinsella	IL-17A	Collinsella-Hepatitis B-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-LS
Collinsella	IL-17A	Collinsella-Insulin resistance-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-LS
Collinsella	IL-17A	Collinsella-Prostate cancer-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-LS
Collinsella	IL-17A	Collinsella-NF-kappa B signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	DM-LS
total_blood_scfa+blood	IL-17A	total_blood_scfa+blood+TUDCA+blood+Eotaxin+IL-17A	Indirect	serum_scfa	serum_cytokines	0.168	0.855	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-17A	[Eubacterium]-Viral myocarditis-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.0692	0.855	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-17A	[Eubacterium]-Pathogenic Escherichia coli infection-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.0692	0.855	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-17A	[Eubacterium]-Phagosome-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.0692	0.855	no	no	no	no	no	no	DM-LS
[Eubacterium]	IL-17A	[Eubacterium]-Salmonella infection+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0692	0.855	no	no	no	no	no	no	DM-LS
LCA+stool	IL-17A	LCA+stool-ACA+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.314	0.855	no	no	no	no	no	no	DM-LS
Akkermansia	IL-17A	Akkermansia-L-Alanine+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	DM-LS
Bifidobacterium	IL-17A	Bifidobacterium-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	DM-LS
Ruminococcus	IL-17A	Ruminococcus+Type I diabetes mellitus-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.335	0.855	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-17A	Ruminococcus+Endocytosis-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.335	0.855	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-17A	Ruminococcus+Allograft rejection-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.335	0.855	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-17A	Ruminococcus+22:6n3+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.335	0.855	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-17A	Ruminococcus+Graft-versus-host disease-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.335	0.855	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-17A	Ruminococcus+Phagosome-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.335	0.855	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-17A	Ruminococcus+Cell adhesion molecules-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.335	0.855	no	no	no	no	no	no	DM-LS
Ruminococcus	IL-17A	Ruminococcus+Autoimmune thyroid disease-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.335	0.855	no	no	no	no	no	no	DM-LS
GCDCA+blood	IL-17A	GCDCA+blood-T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.31	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	Succinivibrio-Phospholipase D signaling pathway-Longevity regulating pathway - multiple species+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	Succinivibrio-Phospholipase D signaling pathway+Hepatitis B-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	Succinivibrio-Phospholipase D signaling pathway-Primary immunodeficiency+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	Succinivibrio-Phospholipase D signaling pathway+Chemical carcinogenesis - receptor activation-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	Succinivibrio-Phospholipase D signaling pathway+Relaxin signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	"Succinivibrio-Phospholipase D signaling pathway+Growth hormone synthesis, secretion and action-FGF basic+IL-17A"	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	Succinivibrio-Phospholipase D signaling pathway+Cortisol synthesis and secretion-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	Succinivibrio-Phospholipase D signaling pathway+Chronic myeloid leukemia-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	Succinivibrio-Phospholipase D signaling pathway+Insulin secretion-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	Succinivibrio-Phospholipase D signaling pathway+Cocaine addiction-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	Succinivibrio-L-Phenylalanine+stool+n3+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	Succinivibrio-Phospholipase D signaling pathway+Cushing syndrome+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	Succinivibrio-Phospholipase D signaling pathway-MUFA%+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	Succinivibrio-L-Phenylalanine+stool+Cysteine+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	Succinivibrio-Phospholipase D signaling pathway+Chemical carcinogenesis - receptor activation+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	Succinivibrio-L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	Succinivibrio-L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
Succinivibrio	IL-17A	Succinivibrio-Phospholipase D signaling pathway-UFA%+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.138	0.855	no	no	no	no	no	no	DM-LS
ACA+blood	IL-17A	ACA+blood-Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.338	0.855	no	no	no	no	no	no	DM-LS
DCA+stool	IL-17A	DCA+stool-UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.195	0.855	no	no	no	no	no	no	DM-LS
DCA+stool	IL-17A	DCA+stool-ACA+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.195	0.855	no	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-17A	Butyric acid+stool+Propionic acid+stool-MUFA%+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.102	0.855	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-17A	Butyric acid+stool+8-HETE+blood-ACA+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.102	0.855	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-17A	Butyric acid+stool+Propionic acid+stool-ACA+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.102	0.855	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-17A	Butyric acid+stool-16:1/16:1-PC+blood+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.102	0.855	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-17A	Butyric acid+stool+AA+blood+Choline+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.102	0.855	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-17A	Butyric acid+stool+Propionic acid+stool-UFA%+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.102	0.855	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-17A	Butyric acid+stool-Phenylacetic acid+stool+Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.102	0.855	dn	no	no	no	no	no	DM-LS
Butyric acid+stool	IL-17A	Butyric acid+stool-Phenylacetic acid+stool-Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.102	0.855	dn	no	no	no	no	no	DM-LS
4-hydroxybenzoic acid+stool	IL-17A	4-hydroxybenzoic acid+stool+ACA+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.855	no	dn	no	no	no	no	DM-LS
GCA+blood	IL-17A	GCA+blood+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.16	0.855	no	no	no	no	no	no	DM-LS
ACA+stool	IL-17A	ACA+stool+Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.417	0.855	no	no	no	no	no	no	DM-LS
ACA+stool	IL-17A	ACA+stool+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.417	0.855	no	no	no	no	no	no	DM-LS
ACA+stool	IL-17A	ACA+stool+20:2+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.417	0.855	no	no	no	no	no	no	DM-LS
CDCA+blood	IL-17A	CDCA+blood-MUFA%+blood-Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.506	0.855	no	no	no	no	no	no	DM-LS
CDCA+blood	IL-17A	CDCA+blood-Cysteine+blood-Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.506	0.855	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-17A	capric acid C6+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	serum_scfa	serum_cytokines	0.433	0.855	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-17A	capric acid C6+blood+TUDCA+blood+Eotaxin+IL-17A	Indirect	serum_scfa	serum_cytokines	0.433	0.855	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-17A	capric acid C6+blood+MUFA%+blood-Eotaxin+IL-17A	Indirect	serum_scfa	serum_cytokines	0.433	0.855	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-17A	capric acid C6+blood-Sarcosine+blood-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.433	0.855	no	no	no	no	no	no	DM-LS
capric acid C6+blood	IL-17A	capric acid C6+blood-L-Alanine+blood-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.433	0.855	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-17A	Pyramidobacter+Insulin resistance-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.45	0.855	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-17A	"Pyramidobacter+Parathyroid hormone synthesis, secretion and action-FGF basic+IL-17A"	Indirect	Genus	serum_cytokines	0.45	0.855	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-17A	Pyramidobacter-Carbon metabolism+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.45	0.855	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-17A	Pyramidobacter+Small cell lung cancer-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.45	0.855	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-17A	Pyramidobacter+Prostate cancer-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.45	0.855	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-17A	Pyramidobacter-Carbon metabolism-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.45	0.855	no	no	no	no	no	no	DM-LS
Pyramidobacter	IL-17A	Pyramidobacter+Glucagon signaling pathway+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.45	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+cAMP signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+Cocaine addiction-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella-Glycolysis / Gluconeogenesis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+18:0-LPC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+L-Alanine+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+Aldosterone synthesis and secretion-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+Insulin secretion-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+Chemical carcinogenesis - receptor activation-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella-Carbon metabolism+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	"Prevotella+Growth hormone synthesis, secretion and action-FGF basic+IL-17A"	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+20:0+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+Cortisol synthesis and secretion-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+Calcium signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+Aldosterone synthesis and secretion+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+Adrenergic signaling in cardiomyocytes+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+Chemical carcinogenesis - receptor activation+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+Inflammatory mediator regulation of TRP channels+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella-Carbon metabolism-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+Amphetamine addiction+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+Dopaminergic synapse+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+Cushing syndrome+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
Prevotella	IL-17A	Prevotella+Melanogenesis+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	DM-LS
TCA+blood	IL-17A	TCA+blood+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.339	0.855	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-17A	iso-DCA+blood+L-Phenylalanine+blood+n3+blood-Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.38	0.855	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-17A	iso-DCA+blood+L-Lysine+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.38	0.855	no	no	no	no	no	no	DM-LS
iso-DCA+blood	IL-17A	iso-DCA+blood+L-Leucine+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.38	0.855	no	no	no	no	no	no	DM-LS
HCA+stool	IL-17A	HCA+stool-Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.155	0.855	no	no	no	no	no	no	DM-LS
Roseburia	IL-17A	Roseburia-20:2+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.495	0.855	no	no	no	no	no	no	DM-LS
12-ketoDCA+stool	IL-17A	12-ketoDCA+stool-L-Alanine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.505	0.855	no	no	no	no	no	no	DM-LS
GLCA+blood	IL-17A	GLCA+blood-Sarcosine+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.319	0.855	no	no	no	no	no	no	DM-LS
L-Tryptophan+stool	IL-17A	L-Tryptophan+stool+n3+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.557	0.855	no	no	no	no	no	no	DM-LS
CA+blood	IL-17A	CA+blood+Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.606	0.855	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IL-17A	L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.398	0.855	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IL-17A	L-Phenylalanine+stool+n3+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.398	0.855	no	no	no	no	no	no	DM-LS
L-Phenylalanine+stool	IL-17A	L-Phenylalanine+stool+Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.398	0.855	no	no	no	no	no	no	DM-LS
butyric acid C4+blood	IL-17A	butyric acid C4+blood+isobutyric acid C4+blood+MUFA%+blood-Eotaxin+IL-17A	Indirect	serum_scfa	serum_cytokines	0.407	0.855	no	no	no	no	no	no	DM-LS
GCA+stool	IL-17A	GCA+stool-DHA+blood-TCA+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	DM-LS
GCA+stool	IL-17A	GCA+stool+L-2-Aminobutyric acid+blood+TCA+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	DM-LS
GCA+stool	IL-17A	GCA+stool+16:0/18:3-PC+blood+L-Alanine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	DM-LS
GCA+stool	IL-17A	GCA+stool+16:0/18:3-PC+blood+Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	DM-LS
GCA+stool	IL-17A	GCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	DM-LS
GCA+stool	IL-17A	GCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	DM-LS
GCA+stool	IL-17A	GCA+stool+nutriCA+stool+CA+blood+Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	DM-LS
GCA+stool	IL-17A	GCA+stool+GCDCA+stool+CA+blood+Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	DM-LS
GCA+stool	IL-17A	GCA+stool+nutriCA+stool-n3+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	DM-LS
GCA+stool	IL-17A	GCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	DM-LS
GCA+stool	IL-17A	GCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	DM-LS
GCA+stool	IL-17A	GCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	DM-LS
GCA+stool	IL-17A	GCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	DM-LS
GCA+stool	IL-17A	GCA+stool+GCDCA+stool-Creatinine+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	DM-LS
GCA+stool	IL-17A	GCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	DM-LS
GCA+stool	IL-17A	GCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	DM-LS
T-a-MCA+blood	IL-17A	T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.478	0.855	no	no	no	no	no	no	DM-LS
Coprococcus	IL-17A	Coprococcus-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	DM-LS
Oscillospira	IL-17A	Oscillospira-Adrenergic signaling in cardiomyocytes+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-LS
Oscillospira	IL-17A	Oscillospira+Peroxisome-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	DM-LS
HCA+blood	IL-17A	HCA+blood-MUFA+blood+MUFA%+blood-Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.544	0.855	no	no	no	no	no	no	DM-LS
iso-LCA+stool	IL-17A	iso-LCA+stool-Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.72	0.855	no	no	no	no	no	no	DM-LS
2-methyl-butyric acid m-C4+blood	IL-17A	2-methyl-butyric acid m-C4+blood-CA+blood+Eotaxin+IL-17A	Indirect	serum_scfa	serum_cytokines	0.262	0.855	no	no	no	no	no	no	DM-LS
DCA+blood	IL-17A	DCA+blood-MUFA%+blood-Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.122	0.855	no	no	no	no	no	no	DM-LS
DCA+blood	IL-17A	DCA+blood-TCA+blood+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.122	0.855	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool-16:0/18:0-PC+blood+18:0-LPC+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool-iso-LCA+blood-Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool-T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood-UFA%+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2/16:0-PC+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool+d18:1-14:0-SM+blood-MUFA%+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool-18:1/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool+UDCA+stool-20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool-16:0/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool-18:0/18:2-PC+blood+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-LS
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool-18:2n6c+blood+20:2+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IL-17A	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.304	0.855	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IL-17A	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.304	0.855	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IL-17A	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.304	0.855	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IL-17A	Indole-3-Acetic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.304	0.855	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IL-17A	Indole-3-Acetic acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.304	0.855	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IL-17A	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.304	0.855	no	no	no	no	no	no	DM-LS
Indole-3-Acetic acid+stool	IL-17A	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.304	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool+18:0/18:1-PC+blood+L-Alanine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool+18:1/18:1-PC+blood+Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool+16:0/20:3-PC+blood+Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool-16:0/20:5-PC+blood+n3+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool-16:0/20:5-PC+blood-MUFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool+18:1/18:1-PC+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool+16:0/20:3-PC+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool-16:0/20:5-PC+blood-20:2+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool+18:1/18:1-PC+blood+20:2+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool+16:0/20:3-PC+blood+20:2+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
TCA+stool	IL-17A	TCA+stool-16:0/20:5-PC+blood+CA+blood+Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-20:2/18:0-PC+blood+L-Alanine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-18:0/20:3-PC+blood+L-Alanine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-16:0-LPC+blood+20:0+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool+EPA+blood-TCA+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-16:0-LPC+blood+16:0/18:2-PI+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool+HDCA+blood-Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool+iso-LCA+stool-Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-16:0/20:3-PC+blood+Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-18:1/18:1-PC+blood+Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-20:2/18:0-PC+blood+Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-18:0/20:3-PC+blood+Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-16:0-LPC+blood+18:0-LPC+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-18:1/20:3-PC+blood-CA+blood+Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-nutriCA+stool+CA+blood+Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool+LCA+stool-ACA+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-18:1-LPE+blood-22:6n3+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-18:1/20:3-PC+blood+20:2+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-18:1-LPC+blood+20:2+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-16:0/20:3-PC+blood+20:2+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-18:1/18:1-PC+blood+20:2+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool+EPA+blood+n3+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-nutriCA+stool-n3+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-18:1-LPE+blood-n3+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-16:0/20:3-PC+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
HDCA+stool	IL-17A	HDCA+stool-18:1/18:1-PC+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	DM-LS
Lachnospira	IL-17A	Lachnospira+Choline+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.279	0.855	no	no	no	no	no	no	DM-LS
Fusobacterium	IL-17A	Fusobacterium+UFA%+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.628	0.855	no	no	no	no	no	no	DM-LS
Fusobacterium	IL-17A	Fusobacterium+MUFA%+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.628	0.855	no	no	no	no	no	no	DM-LS
isobutyric acid C4+blood	IL-17A	isobutyric acid C4+blood+MUFA%+blood-Eotaxin+IL-17A	Indirect	serum_scfa	serum_cytokines	0.0151	0.855	up	up	no	no	no	no	DM-LS
GCDCA+stool	IL-17A	GCDCA+stool-Creatinine+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	DM-LS
GCDCA+stool	IL-17A	GCDCA+stool+CA+blood+Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-Acetic acid+stool-Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-Propionic acid+stool-ACA+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool+L-Phenylalanine+stool+n3+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-Propionic acid+stool-MUFA%+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-Propionic acid+stool-UFA%+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-LS
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-Acetic acid+stool-UFA%+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	DM-LS
Odoribacter	IL-17A	Odoribacter+Choline+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-17A	Isobutyric acid+stool+Phenylacetic acid+stool-Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.408	0.855	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-17A	Isobutyric acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.408	0.855	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-17A	Isobutyric acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.408	0.855	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-17A	Isobutyric acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.408	0.855	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-17A	Isobutyric acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.408	0.855	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-17A	Isobutyric acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.408	0.855	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-17A	Isobutyric acid+stool-nutriCA+stool+CA+blood+Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.408	0.855	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-17A	Isobutyric acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.408	0.855	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-17A	Isobutyric acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.408	0.855	no	no	no	no	no	no	DM-LS
Isobutyric acid+stool	IL-17A	Isobutyric acid+stool-nutriCA+stool-n3+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.408	0.855	no	no	no	no	no	no	DM-LS
Lachnobacterium	IL-17A	Lachnobacterium+T-a-MCA+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.867	0.855	no	no	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool-nutriCA+stool+CA+blood+Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool-nutriCA+stool-n3+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-LS
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	DM-LS
Anaerostipes	IL-17A	Anaerostipes-Non-small cell lung cancer+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.568	0.855	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-17A	Anaerostipes+TUDCA+blood+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.568	0.855	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-17A	Anaerostipes-Hepatitis B-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.568	0.855	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-17A	Anaerostipes-Chronic myeloid leukemia-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.568	0.855	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-17A	Anaerostipes-Insulin resistance-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.568	0.855	no	no	no	no	no	no	DM-LS
Anaerostipes	IL-17A	Anaerostipes-Prostate cancer-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.568	0.855	no	no	no	no	no	no	DM-LS
TUDCA+stool	IL-17A	TUDCA+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.241	0.855	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-17A	Isovaleric acid+stool+Phenylacetic acid+stool-Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.343	0.855	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-17A	Isovaleric acid+stool+L-Phenylalanine+stool+Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.343	0.855	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-17A	Isovaleric acid+stool+Phenylacetic acid+stool+Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.343	0.855	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-17A	Isovaleric acid+stool+L-Phenylalanine+stool+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.343	0.855	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-17A	Isovaleric acid+stool-UDCA+stool-20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.343	0.855	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-17A	Isovaleric acid+stool+L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.343	0.855	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-17A	Isovaleric acid+stool+L-Phenylalanine+stool+n3+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.343	0.855	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-17A	Isovaleric acid+stool-nutriCA+stool-n3+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.343	0.855	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-17A	Isovaleric acid+stool+L-Tryptophan+stool+n3+blood-Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.343	0.855	no	no	no	no	no	no	DM-LS
Isovaleric acid+stool	IL-17A	Isovaleric acid+stool-nutriCA+stool+CA+blood+Eotaxin+IL-17A	Indirect	stool_scfa	serum_cytokines	0.343	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism+Adipocytokine signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella-18:0/22:6-PA+blood-GCA+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism-Prostate cancer-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism-Prostate cancer-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism+Tight junction+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism+Tight junction+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism-Transcriptional misregulation in cancer-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism-Transcriptional misregulation in cancer-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism-Hepatitis B-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism-Hepatitis B-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism-Insulin resistance-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism-Insulin resistance-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism+Biosynthesis of amino acids-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Betaine+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism-Choline metabolism in cancer+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism-Choline metabolism in cancer+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism-Cholinergic synapse+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism-mRNA surveillance pathway+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism-mRNA surveillance pathway+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism-Non-small cell lung cancer+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism-Non-small cell lung cancer+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+18:0/20:2-PC+blood+20:2+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism-Colorectal cancer+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism-Colorectal cancer+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism-Cell cycle+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism+Choline+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism-ErbB signaling pathway+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism-ErbB signaling pathway+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism-Phosphatidylinositol signaling system+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism-Phosphatidylinositol signaling system+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella-18:0/22:6-PA+blood+22:6n3+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism-Gastric cancer+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism-Gastric cancer+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism-Glioma+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism-Glioma+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism-Signaling pathways regulating pluripotency of stem cells+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism-Signaling pathways regulating pluripotency of stem cells+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism-Spliceosome+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism-Spliceosome+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Betaine+blood-CA+blood+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Glutathione metabolism-Long-term potentiation+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
Paraprevotella	IL-17A	Paraprevotella+Arachidonic acid metabolism-Long-term potentiation+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	DM-LS
iso-LCA+blood	IL-17A	iso-LCA+blood-Sarcosine+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.507	0.855	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	IL-17A	Phenylacetic acid+stool-Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.785	0.855	no	no	no	no	no	no	DM-LS
Phenylacetic acid+stool	IL-17A	Phenylacetic acid+stool+Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.785	0.855	no	no	no	no	no	no	DM-LS
Gemmiger	IL-17A	Gemmiger-18:1-LPC+blood+20:2+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-LS
Gemmiger	IL-17A	Gemmiger+L-Phenylalanine+blood+n3+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-LS
Gemmiger	IL-17A	Gemmiger+DHA+blood-TCA+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-17A	GDCA+stool+18:0/18:1-PC+blood+L-Alanine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-17A	GDCA+stool-L-Phenylalanine+blood+n3+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-17A	GDCA+stool-L-Isoleucine+blood+n3+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-17A	GDCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-17A	GDCA+stool-L-Histidine+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-17A	GDCA+stool+20:3/18:0-PC+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-17A	GDCA+stool-L-Isoleucine+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-17A	GDCA+stool+Glycine+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-17A	GDCA+stool+24:1+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-17A	GDCA+stool-Propionic acid+stool-UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-17A	GDCA+stool-L-Histidine+blood+MUFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-17A	GDCA+stool+Glycine+blood+MUFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-17A	GDCA+stool-Propionic acid+stool-MUFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-17A	GDCA+stool+20:3/18:0-PC+blood+ACA+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-17A	GDCA+stool+24:1+blood+ACA+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-17A	GDCA+stool-Propionic acid+stool-ACA+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-LS
GDCA+stool	IL-17A	GDCA+stool+20:3/18:0-PC+blood+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IL-17A	Methanobrevibacter-Sarcosine+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.629	0.855	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IL-17A	Methanobrevibacter+18:0-LPC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.629	0.855	no	no	no	no	no	no	DM-LS
Methanobrevibacter	IL-17A	Methanobrevibacter+n3+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.629	0.855	no	no	no	no	no	no	DM-LS
L-Tyrosine+stool	IL-17A	L-Tyrosine+stool+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.44	0.855	no	no	no	no	no	no	DM-LS
CDCA+stool	IL-17A	CDCA+stool-20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.663	0.855	no	no	no	no	no	no	DM-LS
CA+stool	IL-17A	CA+stool+CA+blood+Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.827	0.855	no	no	no	no	no	no	DM-LS
Slackia	IL-17A	Slackia+Primary immunodeficiency+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.94	0.855	no	no	no	no	no	no	DM-LS
Slackia	IL-17A	Slackia+Platinum drug resistance+Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.94	0.855	no	no	no	no	no	no	DM-LS
Slackia	IL-17A	Slackia-Neutrophil extracellular trap formation-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.94	0.855	no	no	no	no	no	no	DM-LS
Slackia	IL-17A	Slackia-Cysteine+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.94	0.855	no	no	no	no	no	no	DM-LS
HDCA+blood	IL-17A	HDCA+blood-Sarcosine+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.483	0.855	no	no	no	no	no	no	DM-LS
UDCA+stool	IL-17A	UDCA+stool-20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.266	0.855	no	no	no	no	no	no	DM-LS
TDCA+stool	IL-17A	TDCA+stool+UDCA+stool-20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.963	0.855	no	no	no	no	no	no	DM-LS
nutriCA+stool	IL-17A	nutriCA+stool+CA+blood+Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.481	0.855	no	no	no	no	no	no	DM-LS
nutriCA+stool	IL-17A	nutriCA+stool-n3+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.481	0.855	no	no	no	no	no	no	DM-LS
GDCA+blood	IL-17A	GDCA+blood-isocapric acid iso-C6+blood-n3+blood-Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.632	0.855	no	no	no	no	no	no	DM-LS
GDCA+blood	IL-17A	GDCA+blood+iso-LCA+blood-Sarcosine+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.632	0.855	no	no	no	no	no	no	DM-LS
acetic acid C2+blood	IL-17A	acetic acid C2+blood-L-Alanine+blood-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.000193	0.855	up	dn	no	no	no	no	DM-LS
acetic acid C2+blood	IL-17A	acetic acid C2+blood-Sarcosine+blood-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.000193	0.855	up	dn	no	no	no	no	DM-LS
isovaleric acid iso-C5+blood	IL-17A	isovaleric acid iso-C5+blood-TUDCA+blood+Eotaxin+IL-17A	Indirect	serum_scfa	serum_cytokines	0.117	0.855	no	no	no	no	no	no	DM-LS
Adlercreutzia	IL-17A	Adlercreutzia+18:0-LPC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.548	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium+cGMP-PKG signaling pathway+Lipid and atherosclerosis-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium+cGMP-PKG signaling pathway+Endocytosis-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium+cGMP-PKG signaling pathway+IL-17 signaling pathway-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium+PUFA/MUFA+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium-14:0/20:4-PC+blood-UFA%+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium-Acetic acid+stool-UFA%+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
 Clostridium	IL-17A	Clostridium+Acetic acid+stool-UFA%+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	NA	0.855	NA	NA	NA	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium-Acetic acid+stool-UFA%+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
 Clostridium	IL-17A	Clostridium+Acetic acid+stool-UFA%+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	NA	0.855	NA	NA	NA	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium+cGMP-PKG signaling pathway+Fc gamma R-mediated phagocytosis-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium+cGMP-PKG signaling pathway+Neutrophil extracellular trap formation-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium+cGMP-PKG signaling pathway+Pathogenic Escherichia coli infection-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium-18:0/20:2-PC+blood+20:2+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium+CDCA+blood-Cysteine+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium-14:0/20:4-PC+blood-Cysteine+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium-Acetic acid+stool-Cysteine+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
 Clostridium	IL-17A	Clostridium+Acetic acid+stool-Cysteine+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	NA	0.855	NA	NA	NA	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium-Acetic acid+stool-Cysteine+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
 Clostridium	IL-17A	Clostridium+Acetic acid+stool-Cysteine+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	NA	0.855	NA	NA	NA	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium-14:0/20:4-PC+blood-Creatinine+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium-14:0/18:2-PC+blood-Creatinine+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium-14:0/20:4-PC+blood-20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium+CDCA+blood-MUFA%+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium-14:0/20:4-PC+blood-MUFA%+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium+cGMP-PKG signaling pathway+MUFA%+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium-14:0/18:2-PC+blood-MUFA%+blood-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium+cGMP-PKG signaling pathway+C-type lectin receptor signaling pathway-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium-14:0/16:0-PC+blood+Sarcosine+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium-14:0/16:0-PC+blood+16:0/18:2-PI+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium-14:0/18:2-PC+blood+16:0/18:2-PI+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
Clostridium	IL-17A	Clostridium-14:0/16:0-PC+blood+L-Alanine+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool+18:0/18:1-PC+blood+L-Alanine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+Sarcosine+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+n3+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+20:5/18:0-PC+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+Cysteine+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+MUFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+MUFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood-MUFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool+16:0/18:1-PC+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool+18:0/16:0-PC+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood-20:2+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool+18:1/18:1-PC+blood+20:2+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool+16:0/20:3-PC+blood+20:2+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool+18:0/18:1-PC+blood+20:2+blood-Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
T-¦Á-MCA+stool	IL-17A	T-¦Á-MCA+stool-TCA+stool-16:0/20:5-PC+blood+CA+blood+Eotaxin+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.48	0.855	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-8-HETE+blood-ACA+blood-Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-20:3-LPE+blood-22:6n3+blood-Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-20:3-LPE+blood+Choline+blood-Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-L-Lysine+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-L-Arginine+blood+UFA%+blood-Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-20:3-LPE+blood-n3+blood-Eotaxin+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-20:3-LPE+blood+Sarcosine+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-LS
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood+GLCA+blood-Sarcosine+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-17A	Butyricicoccus+Allograft rejection-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.852	0.855	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-17A	Butyricicoccus+Viral myocarditis-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.852	0.855	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-17A	Butyricicoccus+Cell adhesion molecules-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.852	0.855	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-17A	Butyricicoccus+Type I diabetes mellitus-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.852	0.855	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-17A	Butyricicoccus+Graft-versus-host disease-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.852	0.855	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-17A	Butyricicoccus+Phagosome-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.852	0.855	no	no	no	no	no	no	DM-LS
Butyricicoccus	IL-17A	Butyricicoccus+Autoimmune thyroid disease-Eotaxin+IL-17A	Indirect	Genus	serum_cytokines	0.852	0.855	no	no	no	no	no	no	DM-LS
Blautia	Visfatin	Blautia+Peroxisome+Visfatin	Indirect	Genus	DM-associated hormones	1.36E-05	0.0229	up	dn	dn	dn	no	up	HC
Blautia	Visfatin	Blautia-Chemical carcinogenesis - receptor activation-Visfatin	Indirect	Genus	DM-associated hormones	1.36E-05	0.0229	up	dn	dn	dn	no	up	HC
Blautia	Visfatin	Blautia-Cushing syndrome-Visfatin	Indirect	Genus	DM-associated hormones	1.36E-05	0.0229	up	dn	dn	dn	no	up	HC
Blautia	Visfatin	Blautia+Arginine and proline metabolism+Visfatin	Indirect	Genus	DM-associated hormones	1.36E-05	0.0229	up	dn	dn	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Phenylacetyl L-GlutaMine+urine+PAI-1-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Glycolysis / Gluconeogenesis-Kaposi sarcoma-associated herpesvirus infection-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-Phosphatidylinositol signaling system+Chemical carcinogenesis - receptor activation-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Biosynthesis of amino acids-Chemical carcinogenesis - receptor activation-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-RNA degradation+Chemical carcinogenesis - receptor activation-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Carbon metabolism-Chemical carcinogenesis - receptor activation-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Glycolysis / Gluconeogenesis-Chemical carcinogenesis - receptor activation-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-Pathways in cancer+Chemical carcinogenesis - receptor activation-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-mRNA surveillance pathway+Chemical carcinogenesis - receptor activation-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-Phosphatidylinositol signaling system+Adrenergic signaling in cardiomyocytes-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Biosynthesis of amino acids-Adrenergic signaling in cardiomyocytes-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-RNA degradation+Adrenergic signaling in cardiomyocytes-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Carbon metabolism-Adrenergic signaling in cardiomyocytes-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Glycolysis / Gluconeogenesis-Adrenergic signaling in cardiomyocytes-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-mRNA surveillance pathway+Adrenergic signaling in cardiomyocytes-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-Phosphatidylinositol signaling system+Aldosterone synthesis and secretion-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Biosynthesis of amino acids-Aldosterone synthesis and secretion-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-RNA degradation+Aldosterone synthesis and secretion-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Carbon metabolism-Aldosterone synthesis and secretion-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Glycolysis / Gluconeogenesis-Aldosterone synthesis and secretion-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-mRNA surveillance pathway+Aldosterone synthesis and secretion-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-Phosphatidylinositol signaling system+Cushing syndrome-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Biosynthesis of amino acids-Cushing syndrome-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Carbon metabolism-Cushing syndrome-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-mRNA surveillance pathway+Cushing syndrome-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-Phosphatidylinositol signaling system+Dopaminergic synapse-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Biosynthesis of amino acids-Dopaminergic synapse-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-RNA degradation+Dopaminergic synapse-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Carbon metabolism-Dopaminergic synapse-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Glycolysis / Gluconeogenesis-Dopaminergic synapse-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-mRNA surveillance pathway+Dopaminergic synapse-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-Phosphatidylinositol signaling system+Amphetamine addiction-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Biosynthesis of amino acids-Amphetamine addiction-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-RNA degradation+Amphetamine addiction-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Carbon metabolism-Amphetamine addiction-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Glycolysis / Gluconeogenesis-Amphetamine addiction-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-mRNA surveillance pathway+Amphetamine addiction-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Biosynthesis of amino acids-Morphine addiction-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Biosynthesis of amino acids+Peroxisome+Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-RNA degradation-Peroxisome+Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-mRNA surveillance pathway-Peroxisome+Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	"Parabacteroides+Biosynthesis of amino acids-Parathyroid hormone synthesis, secretion and action-Visfatin"	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	"Parabacteroides-RNA degradation+Parathyroid hormone synthesis, secretion and action-Visfatin"	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	"Parabacteroides+Carbon metabolism-Parathyroid hormone synthesis, secretion and action-Visfatin"	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	"Parabacteroides+Glycolysis / Gluconeogenesis-Parathyroid hormone synthesis, secretion and action-Visfatin"	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	"Parabacteroides-mRNA surveillance pathway+Parathyroid hormone synthesis, secretion and action-Visfatin"	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Biosynthesis of amino acids-Pancreatic secretion-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-RNA degradation+Pancreatic secretion-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Carbon metabolism-Pancreatic secretion-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Glycolysis / Gluconeogenesis-Pancreatic secretion-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-mRNA surveillance pathway+Pancreatic secretion-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Biosynthesis of amino acids+Tuberculosis+Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-RNA degradation-Tuberculosis+Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Carbon metabolism+Tuberculosis+Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-mRNA surveillance pathway-Tuberculosis+Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Biosynthesis of amino acids+Systemic lupus erythematosus+Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-Colorectal cancer-Systemic lupus erythematosus+Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Carbon metabolism+Systemic lupus erythematosus+Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-mRNA surveillance pathway-Systemic lupus erythematosus+Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-Phosphatidylinositol signaling system+Inflammatory mediator regulation of TRP channels-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Biosynthesis of amino acids-Inflammatory mediator regulation of TRP channels-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-RNA degradation+Inflammatory mediator regulation of TRP channels-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides+Carbon metabolism-Inflammatory mediator regulation of TRP channels-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Parabacteroides	Visfatin	Parabacteroides-mRNA surveillance pathway+Inflammatory mediator regulation of TRP channels-Visfatin	Indirect	Genus	DM-associated hormones	4.19E-05	0.0229	no	up	up	dn	no	up	HC
Dorea	Visfatin	Dorea-Amphetamine addiction-Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	HC
Dorea	Visfatin	Dorea-Chemical carcinogenesis - receptor activation-Visfatin	Indirect	Genus	DM-associated hormones	0.00362	0.0229	up	no	dn	dn	no	up	HC
Faecalibacterium	Visfatin	Faecalibacterium-Phenylacetyl L-GlutaMine+urine+PAI-1-Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	HC
Faecalibacterium	Visfatin	Faecalibacterium-Staphylococcus aureus infection-Kaposi sarcoma-associated herpesvirus infection-Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	HC
Faecalibacterium	Visfatin	Faecalibacterium-Staphylococcus aureus infection+Tuberculosis+Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	HC
Faecalibacterium	Visfatin	Faecalibacterium-Staphylococcus aureus infection+Systemic lupus erythematosus+Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	HC
Faecalibacterium	Visfatin	Faecalibacterium+4-hydroxybenzoic acid+stool-ACA+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	HC
Faecalibacterium	Visfatin	Faecalibacterium-Staphylococcus aureus infection-Chemical carcinogenesis - receptor activation-Visfatin	Indirect	Genus	DM-associated hormones	0.0039	0.0229	no	dn	dn	dn	no	up	HC
TUDCA+blood	Visfatin	TUDCA+blood-L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine+Leptin-Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Tryptophan+blood+lauric acid C12+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+lauric acid C12+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Phenylalanine+blood+lauric acid C12+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+lauric acid C12+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+lauric acid C12+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood+lauric acid C12+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Tryptophan+blood+MUFA%+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+MUFA%+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+MUFA%+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+L-Histidine+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Tryptophan+blood+lauric acid C12+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+lauric acid C12+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Phenylalanine+blood+lauric acid C12+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+lauric acid C12+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+lauric acid C12+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood+lauric acid C12+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+Serine+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+Serine+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+Serine+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+L-Glutamine+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine+Leptin-PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Tryptophan+blood+MUFA%+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+MUFA%+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+MUFA%+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+Serine+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+Serine+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+Serine+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+L-Glutamine+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+L-Histidine+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Tryptophan+blood+MUFA%+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+MUFA%+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+MUFA%+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+Serine+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+Serine+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+Serine+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+UFA%+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+L-Glutamine+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	Visfatin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.0229	no	no	dn	dn	no	up	HC
Bacteroides	Visfatin	Bacteroides+Systemic lupus erythematosus+Visfatin	Indirect	Genus	DM-associated hormones	0.000267	0.0229	dn	dn	up	dn	no	up	HC
Propionic acid+stool	Visfatin	Propionic acid+stool+Homovanillic acid+urine-PAI-1-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.0229	dn	no	up	dn	no	up	HC
[Ruminococcus]	Visfatin	[Ruminococcus]-18:0/20:4-PI+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.0679	0.0229	no	no	dn	dn	no	up	HC
GUDCA+blood	Visfatin	GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.0229	no	no	dn	dn	no	up	HC
GUDCA+blood	Visfatin	GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.0229	no	no	dn	dn	no	up	HC
GUDCA+blood	Visfatin	GUDCA+blood-UFA%+blood+L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.0229	no	no	dn	dn	no	up	HC
GUDCA+blood	Visfatin	GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.0229	no	no	dn	dn	no	up	HC
GUDCA+blood	Visfatin	GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.0229	no	no	dn	dn	no	up	HC
GUDCA+blood	Visfatin	GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.0229	no	no	dn	dn	no	up	HC
GUDCA+blood	Visfatin	GUDCA+blood-PUFA%+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.0229	no	no	dn	dn	no	up	HC
GUDCA+blood	Visfatin	GUDCA+blood-UFA%+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.0229	no	no	dn	dn	no	up	HC
GUDCA+blood	Visfatin	GUDCA+blood-PUFA%+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.0229	no	no	dn	dn	no	up	HC
GUDCA+blood	Visfatin	GUDCA+blood-PUFA/UFA+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.0229	no	no	dn	dn	no	up	HC
GUDCA+blood	Visfatin	GUDCA+blood-iso-DCA+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.0229	no	no	dn	dn	no	up	HC
GUDCA+blood	Visfatin	GUDCA+blood-iso-DCA+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.0229	no	no	dn	dn	no	up	HC
GUDCA+blood	Visfatin	GUDCA+blood-PUFA%+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.0229	no	no	dn	dn	no	up	HC
GUDCA+blood	Visfatin	GUDCA+blood-PUFA/UFA+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.0229	no	no	dn	dn	no	up	HC
Acetic acid+stool	Visfatin	Acetic acid+stool+Homovanillic acid+urine-PAI-1-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.0229	dn	no	no	dn	no	up	HC
Alistipes	Visfatin	Alistipes-Peroxisome+Visfatin	Indirect	Genus	DM-associated hormones	0.0114	0.0229	no	up	no	dn	no	up	HC
Alistipes	Visfatin	Alistipes+PAI-1-Visfatin	Indirect	Genus	DM-associated hormones	0.0114	0.0229	no	up	no	dn	no	up	HC
Butyricimonas	Visfatin	Butyricimonas+Viral protein interaction with cytokine and cytokine receptor-Visfatin	Indirect	Genus	DM-associated hormones	0.17	0.0229	no	no	no	dn	no	up	HC
Butyricimonas	Visfatin	Butyricimonas+Adrenergic signaling in cardiomyocytes-Visfatin	Indirect	Genus	DM-associated hormones	0.17	0.0229	no	no	no	dn	no	up	HC
Butyricimonas	Visfatin	Butyricimonas+Inflammatory mediator regulation of TRP channels-Visfatin	Indirect	Genus	DM-associated hormones	0.17	0.0229	no	no	no	dn	no	up	HC
Butyricimonas	Visfatin	Butyricimonas+Dopaminergic synapse-Visfatin	Indirect	Genus	DM-associated hormones	0.17	0.0229	no	no	no	dn	no	up	HC
Butyricimonas	Visfatin	Butyricimonas+Morphine addiction-Visfatin	Indirect	Genus	DM-associated hormones	0.17	0.0229	no	no	no	dn	no	up	HC
Butyricimonas	Visfatin	"Butyricimonas+Parathyroid hormone synthesis, secretion and action-Visfatin"	Indirect	Genus	DM-associated hormones	0.17	0.0229	no	no	no	dn	no	up	HC
Butyricimonas	Visfatin	Butyricimonas+Pancreatic secretion-Visfatin	Indirect	Genus	DM-associated hormones	0.17	0.0229	no	no	no	dn	no	up	HC
Collinsella	Visfatin	Collinsella+Porphyrin and chlorophyll metabolism+Gap junction-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	HC
Collinsella	Visfatin	"Collinsella+Glycine, serine and threonine metabolism+Gap junction-Visfatin"	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	HC
Collinsella	Visfatin	"Collinsella+Glycine, serine and threonine metabolism-Arginine and proline metabolism+Visfatin"	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	HC
Collinsella	Visfatin	Collinsella-TMAO+blood+Resistin+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	HC
Collinsella	Visfatin	Collinsella-L-Tryptophan+urine+PAI-1-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	HC
Collinsella	Visfatin	Collinsella-18:2-LPC+blood+PAI-1-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	HC
Collinsella	Visfatin	Collinsella-18:2/18:2-PC+blood+PAI-1-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	HC
Collinsella	Visfatin	Collinsella+Porphyrin and chlorophyll metabolism-18:0/20:4-PI+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	HC
Collinsella	Visfatin	"Collinsella+Glycine, serine and threonine metabolism-18:0/20:4-PI+blood+Visfatin"	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	HC
Collinsella	Visfatin	Collinsella+Porphyrin and chlorophyll metabolism+Renin secretion-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	HC
Collinsella	Visfatin	"Collinsella+Glycine, serine and threonine metabolism+Renin secretion-Visfatin"	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	HC
Collinsella	Visfatin	Collinsella+Porphyrin and chlorophyll metabolism+Thyroid hormone synthesis-Visfatin	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	HC
Collinsella	Visfatin	"Collinsella+Glycine, serine and threonine metabolism+Thyroid hormone synthesis-Visfatin"	Indirect	Genus	DM-associated hormones	0.128	0.0229	no	no	no	dn	no	up	HC
iso-DCA+stool	Visfatin	iso-DCA+stool-L-Tryptophan+stool+Phenylacetyl L-GlutaMine+urine+PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	HC
iso-DCA+stool	Visfatin	iso-DCA+stool+iso-LCA+stool-Leptin-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	HC
iso-DCA+stool	Visfatin	iso-DCA+stool+LCA+stool-TCA+stool-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	HC
iso-DCA+stool	Visfatin	"iso-DCA+stool-nutriCA+stool-9,10-EPOME+blood+d18:1-24:1-SM+blood+Visfatin"	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	HC
iso-DCA+stool	Visfatin	"iso-DCA+stool+LCA+stool+9,10-EPOME+blood+d18:1-24:1-SM+blood+Visfatin"	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	HC
iso-DCA+stool	Visfatin	iso-DCA+stool-L-Tryptophan+stool-DCA+blood-C-peptide-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	HC
iso-DCA+stool	Visfatin	iso-DCA+stool-UDCA+stool-TMAO+blood+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	HC
iso-DCA+stool	Visfatin	iso-DCA+stool+iso-LCA+stool-Leptin-Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	HC
LCA+stool	Visfatin	"LCA+stool+9,10-EPOME+blood+d18:1-24:1-SM+blood+Visfatin"	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	HC
LCA+stool	Visfatin	LCA+stool-TCA+stool-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.0229	no	no	no	dn	no	up	HC
Akkermansia	Visfatin	Akkermansia+Systemic lupus erythematosus+Visfatin	Indirect	Genus	DM-associated hormones	0.23	0.0229	no	no	no	dn	no	up	HC
Bifidobacterium	Visfatin	Bifidobacterium-18:2-LPE+blood-d18:1-24:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.105	0.0229	no	dn	no	dn	no	up	HC
Bifidobacterium	Visfatin	Bifidobacterium-DCA+blood-C-peptide-Visfatin	Indirect	Genus	DM-associated hormones	0.105	0.0229	no	dn	no	dn	no	up	HC
Bifidobacterium	Visfatin	Bifidobacterium-Intestinal immune network for IgA production+ACA+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.105	0.0229	no	dn	no	dn	no	up	HC
Phenylacetyl L-GlutaMine+urine	Visfatin	Phenylacetyl L-GlutaMine+urine+PAI-1-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.0909	0.0229	up	no	no	dn	no	up	HC
Ruminococcus	Visfatin	Ruminococcus-Visfatin	Direct	Genus	DM-associated hormones	0.335	0.0229	no	no	no	dn	no	up	HC
GCDCA+blood	Visfatin	GCDCA+blood-iso-DCA+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	HC
GCDCA+blood	Visfatin	GCDCA+blood-MUFA%+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	HC
GCDCA+blood	Visfatin	GCDCA+blood-PUFA%+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	HC
GCDCA+blood	Visfatin	GCDCA+blood-iso-DCA+blood+L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	HC
GCDCA+blood	Visfatin	GCDCA+blood-UFA%+blood+L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	HC
GCDCA+blood	Visfatin	GCDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	HC
GCDCA+blood	Visfatin	GCDCA+blood-PUFA%+blood+L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	HC
GCDCA+blood	Visfatin	GCDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	HC
GCDCA+blood	Visfatin	GCDCA+blood-UFA%+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	HC
GCDCA+blood	Visfatin	GCDCA+blood-MUFA%+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	HC
GCDCA+blood	Visfatin	GCDCA+blood-PUFA%+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	HC
GCDCA+blood	Visfatin	GCDCA+blood-iso-DCA+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	HC
GCDCA+blood	Visfatin	GCDCA+blood-MUFA%+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	HC
GCDCA+blood	Visfatin	GCDCA+blood-PUFA%+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.0229	no	no	no	dn	no	up	HC
[Prevotella]	Visfatin	[Prevotella]-Aldosterone synthesis and secretion-Visfatin	Indirect	Genus	DM-associated hormones	0.367	0.0229	no	no	no	dn	no	up	HC
[Prevotella]	Visfatin	[Prevotella]-ACA+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.367	0.0229	no	no	no	dn	no	up	HC
[Prevotella]	Visfatin	[Prevotella]-Gap junction-Visfatin	Indirect	Genus	DM-associated hormones	0.367	0.0229	no	no	no	dn	no	up	HC
[Prevotella]	Visfatin	[Prevotella]-Morphine addiction-Visfatin	Indirect	Genus	DM-associated hormones	0.367	0.0229	no	no	no	dn	no	up	HC
ACA+blood	Visfatin	ACA+blood-TUDCA+blood-L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.0229	no	no	no	dn	no	up	HC
ACA+blood	Visfatin	ACA+blood-P-hydroxyhippuric acid+urine-FGF basic+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.0229	no	no	no	dn	no	up	HC
ACA+blood	Visfatin	ACA+blood-P-hydroxyhippuric acid+urine+Leptin-PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.0229	no	no	no	dn	no	up	HC
ACA+blood	Visfatin	ACA+blood-P-hydroxyhippuric acid+urine+Leptin-Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.0229	no	no	no	dn	no	up	HC
ACA+blood	Visfatin	ACA+blood+iso-LCA+blood-n3+blood-Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.0229	no	no	no	dn	no	up	HC
ACA+blood	Visfatin	ACA+blood+LCA+blood-n3+blood-Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.0229	no	no	no	dn	no	up	HC
DCA+stool	Visfatin	DCA+stool-DL-methionine sulfoxide+blood-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.0229	no	no	no	dn	no	up	HC
2-hydroxyhippuric acid+urine	Visfatin	2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.215	0.0229	no	no	no	dn	no	up	HC
Butyric acid+stool	Visfatin	Butyric acid+stool+HDCA+stool+PAI-1-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.102	0.0229	dn	no	no	dn	no	up	HC
Butyric acid+stool	Visfatin	Butyric acid+stool-d18:1-22:0-SM+blood+d18:1-24:1-SM+blood+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.102	0.0229	dn	no	no	dn	no	up	HC
4-hydroxybenzoic acid+stool	Visfatin	4-hydroxybenzoic acid+stool-ACA+stool-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.0229	no	dn	no	dn	no	up	HC
GCA+blood	Visfatin	GCA+blood-iso-DCA+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.0229	no	no	no	dn	no	up	HC
GCA+blood	Visfatin	GCA+blood-iso-DCA+blood+L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.0229	no	no	no	dn	no	up	HC
GCA+blood	Visfatin	GCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.0229	no	no	no	dn	no	up	HC
GCA+blood	Visfatin	GCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.0229	no	no	no	dn	no	up	HC
GCA+blood	Visfatin	GCA+blood-iso-DCA+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.0229	no	no	no	dn	no	up	HC
ACA+stool	Visfatin	ACA+stool-Visfatin	Direct	stool_bileacids	DM-associated hormones	0.417	0.0229	no	no	no	dn	no	up	HC
CDCA+blood	Visfatin	CDCA+blood+DCA+blood-C-peptide-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.0229	no	no	no	dn	no	up	HC
capric acid C6+blood	Visfatin	capric acid C6+blood-Cystine+blood+L-Aspartic acid+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.433	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-Lysosome+Systemic lupus erythematosus+Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-18:1/18:1-PC+blood+PAI-1-Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-SFA%+blood+PAI-1-Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-B cell receptor signaling pathway-Circadian entrainment-Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-IL-17 signaling pathway-Amphetamine addiction-Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella+Estrogen signaling pathway+Amphetamine addiction-Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-Lysosome-Amphetamine addiction-Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-IL-17 signaling pathway-Cushing syndrome-Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-Lysosome-Cushing syndrome-Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-B cell receptor signaling pathway-Renin secretion-Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-IL-17 signaling pathway-Renin secretion-Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella+Estrogen signaling pathway+Renin secretion-Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-IL-17 signaling pathway+Tuberculosis+Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-Lysosome+Tuberculosis+Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-B cell receptor signaling pathway-Thyroid hormone synthesis-Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-IL-17 signaling pathway-Thyroid hormone synthesis-Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-Lysosome-Thyroid hormone synthesis-Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella+Estrogen signaling pathway+Chemical carcinogenesis - receptor activation-Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-18:0/20:4-PC+blood+18:0/20:4-PI+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-16:1/16:1-PC+blood+18:0/20:4-PI+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella+Estrogen signaling pathway-Kaposi sarcoma-associated herpesvirus infection-Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
Prevotella	Visfatin	Prevotella-18:1/20:4-PC+blood+d18:1-24:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.287	0.0229	no	no	no	dn	no	up	HC
TCA+blood	Visfatin	TCA+blood+P-hydroxyhippuric acid+urine+Leptin-Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.339	0.0229	no	no	no	dn	no	up	HC
TCA+blood	Visfatin	TCA+blood+TUDCA+blood-L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.339	0.0229	no	no	no	dn	no	up	HC
TCA+blood	Visfatin	TCA+blood+P-hydroxyhippuric acid+urine-FGF basic+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.339	0.0229	no	no	no	dn	no	up	HC
TCA+blood	Visfatin	TCA+blood+P-hydroxyhippuric acid+urine+Leptin-PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.339	0.0229	no	no	no	dn	no	up	HC
iso-DCA+blood	Visfatin	iso-DCA+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.0229	no	no	no	dn	no	up	HC
iso-DCA+blood	Visfatin	iso-DCA+blood+L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.0229	no	no	no	dn	no	up	HC
iso-DCA+blood	Visfatin	iso-DCA+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.0229	no	no	no	dn	no	up	HC
HCA+stool	Visfatin	HCA+stool+16:1+blood+18:0/20:4-PI+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.0229	no	no	no	dn	no	up	HC
Roseburia	Visfatin	Roseburia-ACA+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.495	0.0229	no	no	no	dn	no	up	HC
12-ketoDCA+stool	Visfatin	12-ketoDCA+stool-CA+stool+GCA+stool+GCDCA+stool-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.0229	no	no	no	dn	no	up	HC
12-ketoDCA+stool	Visfatin	12-ketoDCA+stool-CDCA+stool+GCA+stool+GCDCA+stool-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.0229	no	no	no	dn	no	up	HC
12-ketoDCA+stool	Visfatin	12-ketoDCA+stool-Cystine+blood+L-Aspartic acid+blood+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.0229	no	no	no	dn	no	up	HC
12-ketoDCA+stool	Visfatin	12-ketoDCA+stool-CDCA+stool+Leptin-Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.0229	no	no	no	dn	no	up	HC
12-ketoDCA+stool	Visfatin	"12-ketoDCA+stool+LCA+stool+9,10-EPOME+blood+d18:1-24:1-SM+blood+Visfatin"	Indirect	stool_bileacids	DM-associated hormones	0.505	0.0229	no	no	no	dn	no	up	HC
12-ketoDCA+stool	Visfatin	12-ketoDCA+stool+LCA+stool-TCA+stool-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.0229	no	no	no	dn	no	up	HC
12-ketoDCA+stool	Visfatin	12-ketoDCA+stool-CDCA+stool+Leptin-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.0229	no	no	no	dn	no	up	HC
12-ketoDCA+stool	Visfatin	12-ketoDCA+stool-TUDCA+blood-L-Tryptophan+urine+PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.0229	no	no	no	dn	no	up	HC
12-ketoDCA+stool	Visfatin	12-ketoDCA+stool+DCA+stool-DL-methionine sulfoxide+blood-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.0229	no	no	no	dn	no	up	HC
12-ketoDCA+stool	Visfatin	12-ketoDCA+stool-CA+stool-HDCA+stool+PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.0229	no	no	no	dn	no	up	HC
12-ketoDCA+stool	Visfatin	12-ketoDCA+stool-CDCA+stool-HDCA+stool+PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.0229	no	no	no	dn	no	up	HC
GLCA+blood	Visfatin	GLCA+blood+L-Glutamine+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.0229	no	no	no	dn	no	up	HC
GLCA+blood	Visfatin	GLCA+blood+L-Glutamine+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.0229	no	no	no	dn	no	up	HC
GLCA+blood	Visfatin	GLCA+blood+L-Glutamine+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.0229	no	no	no	dn	no	up	HC
GLCA+blood	Visfatin	GLCA+blood+LCA+blood-n3+blood-Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.0229	no	no	no	dn	no	up	HC
GLCA+blood	Visfatin	GLCA+blood+iso-LCA+blood-n3+blood-Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.0229	no	no	no	dn	no	up	HC
L-Tryptophan+stool	Visfatin	L-Tryptophan+stool-DCA+blood-C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.0229	no	no	no	dn	no	up	HC
L-Tryptophan+stool	Visfatin	L-Tryptophan+stool+Phenylacetyl L-GlutaMine+urine+PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.0229	no	no	no	dn	no	up	HC
CA+blood	Visfatin	CA+blood+LCA+blood-n3+blood-Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.0229	no	no	no	dn	no	up	HC
CA+blood	Visfatin	CA+blood+CDCA+blood+DCA+blood-C-peptide-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.0229	no	no	no	dn	no	up	HC
GUDCA+stool	Visfatin	GUDCA+stool+L-Tryptophan+stool-DCA+blood-C-peptide-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.0229	no	dn	no	dn	no	up	HC
GUDCA+stool	Visfatin	GUDCA+stool+Phenylacetic acid+stool+n6/n3+blood+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.0229	no	dn	no	dn	no	up	HC
GUDCA+stool	Visfatin	GUDCA+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.0229	no	dn	no	dn	no	up	HC
GUDCA+stool	Visfatin	GUDCA+stool+Phenylacetic acid+stool-Leptin-Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.0229	no	dn	no	dn	no	up	HC
GUDCA+stool	Visfatin	GUDCA+stool+Phenylacetic acid+stool-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.0229	no	dn	no	dn	no	up	HC
GUDCA+stool	Visfatin	GUDCA+stool+Phenylacetic acid+stool-22:6n3+blood-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.0229	no	dn	no	dn	no	up	HC
GUDCA+stool	Visfatin	GUDCA+stool+Phenylacetic acid+stool+Phenylacetyl L-GlutaMine+urine+PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.0229	no	dn	no	dn	no	up	HC
GUDCA+stool	Visfatin	GUDCA+stool+L-Tryptophan+stool+Phenylacetyl L-GlutaMine+urine+PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.0229	no	dn	no	dn	no	up	HC
GUDCA+stool	Visfatin	GUDCA+stool+Phenylacetic acid+stool-Leptin-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.0229	no	dn	no	dn	no	up	HC
GUDCA+stool	Visfatin	GUDCA+stool+Phenylacetic acid+stool+20:0+blood+PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.0229	no	dn	no	dn	no	up	HC
GUDCA+stool	Visfatin	GUDCA+stool+Phenylacetic acid+stool+18:2/18:2-PC+blood+PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.0229	no	dn	no	dn	no	up	HC
L-Phenylalanine+stool	Visfatin	L-Phenylalanine+stool-DCA+blood-C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.0229	no	no	no	dn	no	up	HC
L-Phenylalanine+stool	Visfatin	L-Phenylalanine+stool-Leptin-Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.0229	no	no	no	dn	no	up	HC
L-Phenylalanine+stool	Visfatin	L-Phenylalanine+stool-Leptin-PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.0229	no	no	no	dn	no	up	HC
L-Phenylalanine+stool	Visfatin	L-Phenylalanine+stool+Phenylacetyl L-GlutaMine+urine+PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.0229	no	no	no	dn	no	up	HC
butyric acid C4+blood	Visfatin	butyric acid C4+blood-DCA+blood-C-peptide-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.407	0.0229	no	no	no	dn	no	up	HC
GCA+stool	Visfatin	GCA+stool+GCDCA+stool-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.0229	no	no	no	dn	no	up	HC
Coprococcus	Visfatin	Coprococcus+d18:1-24:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.612	0.0229	no	no	no	dn	no	up	HC
Oscillospira	Visfatin	Oscillospira+C-peptide-Visfatin	Indirect	Genus	DM-associated hormones	0.62	0.0229	no	no	no	dn	no	up	HC
HCA+blood	Visfatin	HCA+blood-MUFA%+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.544	0.0229	no	no	no	dn	no	up	HC
HCA+blood	Visfatin	HCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.544	0.0229	no	no	no	dn	no	up	HC
HCA+blood	Visfatin	HCA+blood-MUFA%+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.544	0.0229	no	no	no	dn	no	up	HC
HCA+blood	Visfatin	HCA+blood-MUFA%+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.544	0.0229	no	no	no	dn	no	up	HC
iso-LCA+stool	Visfatin	iso-LCA+stool-Leptin-Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	HC
iso-LCA+stool	Visfatin	iso-LCA+stool-Leptin-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.0229	no	no	no	dn	no	up	HC
2-methyl-butyric acid m-C4+blood	Visfatin	2-methyl-butyric acid m-C4+blood+20:1+blood-22:6n3+blood-PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.262	0.0229	no	no	no	dn	no	up	HC
2-methyl-butyric acid m-C4+blood	Visfatin	2-methyl-butyric acid m-C4+blood+butyric acid C4+blood-DCA+blood-C-peptide-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.262	0.0229	no	no	no	dn	no	up	HC
2-methyl-butyric acid m-C4+blood	Visfatin	2-methyl-butyric acid m-C4+blood-22:2-LPA+blood-d18:0-24:1-SM+blood+d18:1-24:1-SM+blood+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.262	0.0229	no	no	no	dn	no	up	HC
2-methyl-butyric acid m-C4+blood	Visfatin	2-methyl-butyric acid m-C4+blood-22:2-LPA+blood-d18:0-24:1-SM+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.262	0.0229	no	no	no	dn	no	up	HC
2-methyl-butyric acid m-C4+blood	Visfatin	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.262	0.0229	no	no	no	dn	no	up	HC
2-methyl-butyric acid m-C4+blood	Visfatin	2-methyl-butyric acid m-C4+blood+20:1+blood-DHA+blood-Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.262	0.0229	no	no	no	dn	no	up	HC
2-methyl-butyric acid m-C4+blood	Visfatin	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.262	0.0229	no	no	no	dn	no	up	HC
DCA+blood	Visfatin	DCA+blood-C-peptide-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.0229	no	no	no	dn	no	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	Visfatin	3-(3-Hydroxyphenyl)propanoic acid+stool+14:0/18:2-PC+blood-Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.0229	no	no	no	dn	no	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	Visfatin	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/20:3-PC+blood-Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.0229	no	no	no	dn	no	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	Visfatin	3-(3-Hydroxyphenyl)propanoic acid+stool+DHA+blood-Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.0229	no	no	no	dn	no	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	Visfatin	3-(3-Hydroxyphenyl)propanoic acid+stool+20:2/18:0-PC+blood-Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.0229	no	no	no	dn	no	up	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	Visfatin	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine+Leptin-PAI-1-Visfatin"	Indirect	urine_cometabolism	DM-associated hormones	0.0125	0.0229	up	up	no	dn	no	up	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	Visfatin	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+PAI-1-Visfatin"	Indirect	urine_cometabolism	DM-associated hormones	0.0125	0.0229	up	up	no	dn	no	up	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	Visfatin	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine+Leptin-Resistin+Visfatin"	Indirect	urine_cometabolism	DM-associated hormones	0.0125	0.0229	up	up	no	dn	no	up	HC
GLCA+stool	Visfatin	GLCA+stool-iso-LCA+stool-Leptin-Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.0229	no	no	no	dn	no	up	HC
GLCA+stool	Visfatin	GLCA+stool-iso-LCA+stool-Leptin-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.0229	no	no	no	dn	no	up	HC
GLCA+stool	Visfatin	GLCA+stool-LCA+stool-TCA+stool-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.0229	no	no	no	dn	no	up	HC
GLCA+stool	Visfatin	"GLCA+stool-LCA+stool+9,10-EPOME+blood+d18:1-24:1-SM+blood+Visfatin"	Indirect	stool_bileacids	DM-associated hormones	0.617	0.0229	no	no	no	dn	no	up	HC
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-Leptin-Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	HC
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-Leptin-Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	HC
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	HC
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+n6/n3+blood+Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	HC
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-Leptin-PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	HC
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-Leptin-PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	HC
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+Phenylacetyl L-GlutaMine+urine+PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	HC
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+Phenylacetyl L-GlutaMine+urine+PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	HC
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Tryptophan+stool+Phenylacetyl L-GlutaMine+urine+PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	HC
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+18:2/18:2-PC+blood+PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	HC
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+20:0+blood+PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	HC
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-22:6n3+blood-PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	HC
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	HC
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-DCA+blood-C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	HC
Indole-3-Acetic acid+stool	Visfatin	Indole-3-Acetic acid+stool+L-Tryptophan+stool-DCA+blood-C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.0229	no	no	no	dn	no	up	HC
TCA+stool	Visfatin	TCA+stool-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.0229	no	no	no	dn	no	up	HC
HDCA+stool	Visfatin	HDCA+stool+PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.0229	no	no	no	dn	no	up	HC
Lachnospira	Visfatin	Lachnospira+GCDCA+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	HC
Lachnospira	Visfatin	Lachnospira-PAI-1-Visfatin	Indirect	Genus	DM-associated hormones	0.279	0.0229	no	no	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood-PUFA/MUFA+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+Serine+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+MUFA%+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood+MUFA%+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Tryptophan+blood+MUFA%+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood-PUFA/MUFA+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+Serine+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+MUFA%+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood+MUFA%+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Tryptophan+blood+MUFA%+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood-PUFA/MUFA+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+Serine+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Phenylalanine+blood+lauric acid C12+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+lauric acid C12+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Tryptophan+blood+lauric acid C12+blood+TMAO+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Phenylalanine+blood+lauric acid C12+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+lauric acid C12+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Tryptophan+blood+lauric acid C12+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+MUFA%+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood+MUFA%+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
isobutyric acid C4+blood	Visfatin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Tryptophan+blood+MUFA%+blood+n6/n3+blood+Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.0229	up	up	no	dn	no	up	HC
GCDCA+stool	Visfatin	GCDCA+stool-Visfatin	Direct	stool_bileacids	DM-associated hormones	0.0471	0.0229	no	dn	no	dn	no	up	HC
5-Hydroxytryptamine+stool	Visfatin	5-Hydroxytryptamine+stool+GCDCA+stool-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.0229	dn	dn	no	dn	no	up	HC
Odoribacter	Visfatin	Odoribacter-Morphine addiction-Visfatin	Indirect	Genus	DM-associated hormones	0.798	0.0229	no	no	no	dn	no	up	HC
Odoribacter	Visfatin	Odoribacter-Gap junction-Visfatin	Indirect	Genus	DM-associated hormones	0.798	0.0229	no	no	no	dn	no	up	HC
Odoribacter	Visfatin	Odoribacter-C-peptide-Visfatin	Indirect	Genus	DM-associated hormones	0.798	0.0229	no	no	no	dn	no	up	HC
Odoribacter	Visfatin	Odoribacter+Arginine and proline metabolism+Visfatin	Indirect	Genus	DM-associated hormones	0.798	0.0229	no	no	no	dn	no	up	HC
Odoribacter	Visfatin	Odoribacter-Pancreatic secretion-Visfatin	Indirect	Genus	DM-associated hormones	0.798	0.0229	no	no	no	dn	no	up	HC
Odoribacter	Visfatin	Odoribacter-Aldosterone synthesis and secretion-Visfatin	Indirect	Genus	DM-associated hormones	0.798	0.0229	no	no	no	dn	no	up	HC
Odoribacter	Visfatin	Odoribacter-Cushing syndrome-Visfatin	Indirect	Genus	DM-associated hormones	0.798	0.0229	no	no	no	dn	no	up	HC
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Resistin+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	HC
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool-Leptin-Resistin+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	HC
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool+n6/n3+blood+Resistin+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	HC
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	HC
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool-22:6n3+blood-PAI-1-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	HC
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool+Phenylacetyl L-GlutaMine+urine+PAI-1-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	HC
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool-Leptin-PAI-1-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	HC
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+PAI-1-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	HC
Isobutyric acid+stool	Visfatin	Isobutyric acid+stool+Phenylacetic acid+stool+18:2/18:2-PC+blood+PAI-1-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.408	0.0229	no	no	no	dn	no	up	HC
2-hydroxyphenylacetic acid+urine	Visfatin	2-hydroxyphenylacetic acid+urine-Phenylacetyl L-GlutaMine+urine+PAI-1-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.763	0.0229	no	no	no	dn	no	up	HC
Kynurenic acid+stool	Visfatin	"Kynurenic acid+stool-nutriCA+stool-9,10-EPOME+blood+d18:1-24:1-SM+blood+Visfatin"	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	HC
Kynurenic acid+stool	Visfatin	Kynurenic acid+stool-UDCA+stool-TMAO+blood+Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.0229	dn	dn	no	dn	no	up	HC
L-Tryptophan+urine	Visfatin	L-Tryptophan+urine+PAI-1-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.226	0.0229	no	no	no	dn	no	up	HC
Eggerthella	Visfatin	Eggerthella+Clostridium-Cushing syndrome-Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	HC
Eggerthella	Visfatin	Eggerthella+Clostridium-d18:1-24:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	HC
 Eggerthella	Visfatin	Eggerthella+Clostridium-d18:1-24:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	NA	0.0229	NA	NA	NA	dn	no	up	HC
Eggerthella	Visfatin	Eggerthella+Clostridium-d18:1-24:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	HC
 Eggerthella	Visfatin	Eggerthella+Clostridium-d18:1-24:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	NA	0.0229	NA	NA	NA	dn	no	up	HC
Eggerthella	Visfatin	Eggerthella-Gemmiger-Tuberculosis+Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	HC
Eggerthella	Visfatin	Eggerthella+Clostridium-Chemical carcinogenesis - receptor activation-Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	HC
Eggerthella	Visfatin	Eggerthella+Bacteroides+Systemic lupus erythematosus+Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	HC
Eggerthella	Visfatin	Eggerthella+Clostridium+Peroxisome+Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	HC
Eggerthella	Visfatin	Eggerthella+Clostridium-Adrenergic signaling in cardiomyocytes-Visfatin	Indirect	Genus	DM-associated hormones	0.912	0.0229	no	no	no	dn	no	up	HC
Anaerotruncus	Visfatin	Anaerotruncus-Gemmiger-Tuberculosis+Visfatin	Indirect	Genus	DM-associated hormones	0.904	0.0229	no	no	no	dn	no	up	HC
Anaerostipes	Visfatin	Anaerostipes-C-peptide-Visfatin	Indirect	Genus	DM-associated hormones	0.568	0.0229	no	no	no	dn	no	up	HC
Isovaleric acid+stool	Visfatin	"Isovaleric acid+stool-nutriCA+stool-9,10-EPOME+blood+d18:1-24:1-SM+blood+Visfatin"	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	HC
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool+18:2/18:2-PC+blood+PAI-1-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	HC
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	HC
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool-22:6n3+blood-PAI-1-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	HC
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool+Phenylacetyl L-GlutaMine+urine+PAI-1-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	HC
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool-Leptin-PAI-1-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	HC
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+PAI-1-Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	HC
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Resistin+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	HC
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool-Leptin-Resistin+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	HC
Isovaleric acid+stool	Visfatin	Isovaleric acid+stool+Phenylacetic acid+stool+n6/n3+blood+Resistin+Visfatin	Indirect	stool_scfa	DM-associated hormones	0.343	0.0229	no	no	no	dn	no	up	HC
Paraprevotella	Visfatin	Paraprevotella-Chemical carcinogenesis - receptor activation-Visfatin	Indirect	Genus	DM-associated hormones	0.118	0.0229	no	no	no	dn	no	up	HC
Homovanillic acid+urine	Visfatin	Homovanillic acid+urine-PAI-1-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.45	0.0229	no	no	no	dn	no	up	HC
TDCA+blood	Visfatin	TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.155	0.0229	no	up	no	dn	no	up	HC
iso-LCA+blood	Visfatin	iso-LCA+blood-n3+blood-Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.507	0.0229	no	no	no	dn	no	up	HC
Phenaceturic acid+urine	Visfatin	Phenaceturic acid+urine+Phenylacetyl L-GlutaMine+urine+PAI-1-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.737	0.0229	no	no	no	dn	no	up	HC
¦Ø-MCA+stool	Visfatin	"¦Ø-MCA+stool-LCA+stool+9,10-EPOME+blood+d18:1-24:1-SM+blood+Visfatin"	Indirect	stool_bileacids	DM-associated hormones	0.919	0.0229	no	no	no	dn	no	up	HC
¦Ø-MCA+stool	Visfatin	¦Ø-MCA+stool-Butyric acid+stool-d18:1-22:0-SM+blood+d18:1-24:1-SM+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.0229	no	no	no	dn	no	up	HC
¦Ø-MCA+stool	Visfatin	¦Ø-MCA+stool-LCA+stool-TCA+stool-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.0229	no	no	no	dn	no	up	HC
¦Ø-MCA+stool	Visfatin	¦Ø-MCA+stool-Propionic acid+stool+Homovanillic acid+urine-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.0229	no	no	no	dn	no	up	HC
¦Ø-MCA+stool	Visfatin	¦Ø-MCA+stool-Acetic acid+stool+Homovanillic acid+urine-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.0229	no	no	no	dn	no	up	HC
¦Ø-MCA+stool	Visfatin	¦Ø-MCA+stool-Butyric acid+stool+HDCA+stool+PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.0229	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool+18:2/18:2-PC+blood+PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool-Homovanillic acid+urine-PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool-22:6n3+blood-PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool+Phenylacetyl L-GlutaMine+urine+PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool-Leptin-PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool+20:0+blood+PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool+n6/n3+blood+Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool-14:0/18:2-PC+blood-Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	Visfatin	Phenylacetic acid+stool-Leptin-Resistin+Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.0229	no	no	no	dn	no	up	HC
Gemmiger	Visfatin	Gemmiger-Tuberculosis+Visfatin	Indirect	Genus	DM-associated hormones	0.595	0.0229	no	no	no	dn	no	up	HC
GDCA+stool	Visfatin	GDCA+stool+d18:1-16:0-SM+blood+d18:1-24:1-SM+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	HC
GDCA+stool	Visfatin	GDCA+stool+d18:0-16:0-SM+blood+d18:1-24:1-SM+blood+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	HC
GDCA+stool	Visfatin	GDCA+stool+d18:1-16:0-SM+blood+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.0229	no	no	no	dn	no	up	HC
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool-DCA+blood-C-peptide-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	HC
L-Tyrosine+stool	Visfatin	L-Tyrosine+stool+Phenylacetyl L-GlutaMine+urine+PAI-1-Visfatin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.0229	no	no	no	dn	no	up	HC
CDCA+stool	Visfatin	CDCA+stool+Leptin-PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.0229	no	no	no	dn	no	up	HC
CDCA+stool	Visfatin	CDCA+stool-HDCA+stool+PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.0229	no	no	no	dn	no	up	HC
CDCA+stool	Visfatin	CDCA+stool+GCA+stool+GCDCA+stool-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.0229	no	no	no	dn	no	up	HC
CDCA+stool	Visfatin	CDCA+stool+Leptin-Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.0229	no	no	no	dn	no	up	HC
CA+stool	Visfatin	CA+stool+GCA+stool+GCDCA+stool-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	HC
CA+stool	Visfatin	CA+stool-HDCA+stool+PAI-1-Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.0229	no	no	no	dn	no	up	HC
HDCA+blood	Visfatin	HDCA+blood+L-Aspartic acid+blood+Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.0229	no	no	no	dn	no	up	HC
HDCA+blood	Visfatin	HDCA+blood+SFA%+blood+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.0229	no	no	no	dn	no	up	HC
UDCA+stool	Visfatin	UDCA+stool-TMAO+blood+Resistin+Visfatin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.0229	no	no	no	dn	no	up	HC
LCA+blood	Visfatin	LCA+blood-n3+blood-Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.884	0.0229	no	no	no	dn	no	up	HC
nutriCA+stool	Visfatin	"nutriCA+stool-9,10-EPOME+blood+d18:1-24:1-SM+blood+Visfatin"	Indirect	stool_bileacids	DM-associated hormones	0.481	0.0229	no	no	no	dn	no	up	HC
GDCA+blood	Visfatin	GDCA+blood+TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.632	0.0229	no	no	no	dn	no	up	HC
P-hydroxyhippuric acid+urine	Visfatin	P-hydroxyhippuric acid+urine+Leptin-Resistin+Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.436	0.0229	no	no	no	dn	no	up	HC
P-hydroxyhippuric acid+urine	Visfatin	P-hydroxyhippuric acid+urine+Leptin-PAI-1-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.436	0.0229	no	no	no	dn	no	up	HC
P-hydroxyhippuric acid+urine	Visfatin	P-hydroxyhippuric acid+urine-FGF basic+PAI-1-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.436	0.0229	no	no	no	dn	no	up	HC
acetic acid C2+blood	Visfatin	acetic acid C2+blood+n3+blood-Resistin+Visfatin	Indirect	serum_scfa	DM-associated hormones	0.000193	0.0229	up	dn	no	dn	no	up	HC
isovaleric acid iso-C5+blood	Visfatin	isovaleric acid iso-C5+blood+Sarcosine+blood-L-Phenylalanine+urine+L-Tryptophan+urine+PAI-1-Visfatin	Indirect	serum_scfa	DM-associated hormones	0.117	0.0229	no	no	no	dn	no	up	HC
L-Phenylalanine+urine	Visfatin	L-Phenylalanine+urine+L-Tryptophan+urine+PAI-1-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.0908	0.0229	no	up	no	dn	no	up	HC
Clostridium	Visfatin	Clostridium-Cushing syndrome-Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	HC
Clostridium	Visfatin	Clostridium-d18:1-24:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	HC
 Clostridium	Visfatin	Clostridium-d18:1-24:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	NA	0.0229	NA	NA	NA	dn	no	up	HC
Clostridium	Visfatin	Clostridium-d18:1-24:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	HC
 Clostridium	Visfatin	Clostridium-d18:1-24:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	NA	0.0229	NA	NA	NA	dn	no	up	HC
Clostridium	Visfatin	Clostridium-Chemical carcinogenesis - receptor activation-Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	HC
Clostridium	Visfatin	Clostridium+Peroxisome+Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	HC
Clostridium	Visfatin	Clostridium-Adrenergic signaling in cardiomyocytes-Visfatin	Indirect	Genus	DM-associated hormones	0.925	0.0229	no	no	no	dn	no	up	HC
12-ketoDCA+blood	Visfatin	12-ketoDCA+blood-DPA+blood-Resistin+Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.0229	no	no	no	dn	no	up	HC
12-ketoDCA+blood	Visfatin	12-ketoDCA+blood+DCA+blood-C-peptide-Visfatin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.0229	no	no	no	dn	no	up	HC
Butyricicoccus	Visfatin	Butyricicoccus-Salivary secretion+Pancreatic secretion-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	HC
Butyricicoccus	Visfatin	Butyricicoccus-Salivary secretion+Morphine addiction-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	HC
Butyricicoccus	Visfatin	Butyricicoccus-Hepatocellular carcinoma+GCDCA+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	HC
Butyricicoccus	Visfatin	Butyricicoccus-Focal adhesion+GCDCA+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	HC
Butyricicoccus	Visfatin	Butyricicoccus-Rap1 signaling pathway+GCDCA+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	HC
Butyricicoccus	Visfatin	Butyricicoccus-Leukocyte transendothelial migration+GCDCA+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	HC
Butyricicoccus	Visfatin	Butyricicoccus-Oxytocin signaling pathway+GCDCA+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	HC
Butyricicoccus	Visfatin	Butyricicoccus+d18:1-22:0-SM+blood+d18:1-24:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	HC
Butyricicoccus	Visfatin	Butyricicoccus-Platelet activation+Circadian entrainment-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	HC
Butyricicoccus	Visfatin	Butyricicoccus-18:2-LPC+blood+PAI-1-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	HC
Butyricicoccus	Visfatin	Butyricicoccus-Focal adhesion+Gap junction-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	HC
Butyricicoccus	Visfatin	Butyricicoccus-Rap1 signaling pathway+Gap junction-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	HC
Butyricicoccus	Visfatin	Butyricicoccus-Focal adhesion+Renin secretion-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	HC
Butyricicoccus	Visfatin	Butyricicoccus-Platelet activation+Renin secretion-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	HC
Butyricicoccus	Visfatin	Butyricicoccus-Oxytocin signaling pathway+Renin secretion-Visfatin	Indirect	Genus	DM-associated hormones	0.852	0.0229	no	no	no	dn	no	up	HC
3-Hydroxy-L-kynurenine+urine	Visfatin	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine+PAI-1-Visfatin	Indirect	urine_cometabolism	DM-associated hormones	0.401	0.0229	no	no	no	dn	no	up	HC
Wautersiella	Visfatin	Wautersiella+Butyricicoccus-Salivary secretion+Pancreatic secretion-Visfatin	Indirect	Genus	DM-associated hormones	0.289	0.0229	no	no	no	dn	no	up	HC
Wautersiella	Visfatin	Wautersiella+Butyricicoccus-Salivary secretion+Morphine addiction-Visfatin	Indirect	Genus	DM-associated hormones	0.289	0.0229	no	no	no	dn	no	up	HC
Wautersiella	Visfatin	Wautersiella+Butyricicoccus-Hepatocellular carcinoma+GCDCA+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.289	0.0229	no	no	no	dn	no	up	HC
Wautersiella	Visfatin	Wautersiella+Butyricicoccus-Focal adhesion+GCDCA+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.289	0.0229	no	no	no	dn	no	up	HC
Wautersiella	Visfatin	Wautersiella+Butyricicoccus-Rap1 signaling pathway+GCDCA+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.289	0.0229	no	no	no	dn	no	up	HC
Wautersiella	Visfatin	Wautersiella+Butyricicoccus-Leukocyte transendothelial migration+GCDCA+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.289	0.0229	no	no	no	dn	no	up	HC
Wautersiella	Visfatin	Wautersiella+Butyricicoccus-Oxytocin signaling pathway+GCDCA+stool-Visfatin	Indirect	Genus	DM-associated hormones	0.289	0.0229	no	no	no	dn	no	up	HC
Wautersiella	Visfatin	Wautersiella+Butyricicoccus+d18:1-22:0-SM+blood+d18:1-24:1-SM+blood+Visfatin	Indirect	Genus	DM-associated hormones	0.289	0.0229	no	no	no	dn	no	up	HC
Wautersiella	Visfatin	Wautersiella+Butyricicoccus-Platelet activation+Circadian entrainment-Visfatin	Indirect	Genus	DM-associated hormones	0.289	0.0229	no	no	no	dn	no	up	HC
Wautersiella	Visfatin	Wautersiella+Butyricicoccus-18:2-LPC+blood+PAI-1-Visfatin	Indirect	Genus	DM-associated hormones	0.289	0.0229	no	no	no	dn	no	up	HC
Wautersiella	Visfatin	Wautersiella+Butyricicoccus-Focal adhesion+Gap junction-Visfatin	Indirect	Genus	DM-associated hormones	0.289	0.0229	no	no	no	dn	no	up	HC
Wautersiella	Visfatin	Wautersiella+Butyricicoccus-Rap1 signaling pathway+Gap junction-Visfatin	Indirect	Genus	DM-associated hormones	0.289	0.0229	no	no	no	dn	no	up	HC
Wautersiella	Visfatin	Wautersiella+Butyricicoccus-Focal adhesion+Renin secretion-Visfatin	Indirect	Genus	DM-associated hormones	0.289	0.0229	no	no	no	dn	no	up	HC
Wautersiella	Visfatin	Wautersiella+Butyricicoccus-Platelet activation+Renin secretion-Visfatin	Indirect	Genus	DM-associated hormones	0.289	0.0229	no	no	no	dn	no	up	HC
Wautersiella	Visfatin	Wautersiella+Butyricicoccus-Oxytocin signaling pathway+Renin secretion-Visfatin	Indirect	Genus	DM-associated hormones	0.289	0.0229	no	no	no	dn	no	up	HC
Blautia	PAI-1	Blautia+Peroxisome-PAI-1	Indirect	Genus	DM-associated hormones	1.36E-05	5.10E-05	up	dn	dn	up	up	up	HC
Blautia	PAI-1	Blautia-18:2-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	1.36E-05	5.10E-05	up	dn	dn	up	up	up	HC
Parabacteroides	PAI-1	Parabacteroides+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	Genus	DM-associated hormones	4.19E-05	5.10E-05	no	up	up	up	up	up	HC
Dorea	PAI-1	Dorea-18:2-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.00362	5.10E-05	up	no	dn	up	up	up	HC
Faecalibacterium	PAI-1	Faecalibacterium-Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.0039	5.10E-05	no	dn	dn	up	up	up	HC
TUDCA+blood	PAI-1	TUDCA+blood-L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0282	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine+Leptin-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Tryptophan+blood+MUFA%+blood+SFA%+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+MUFA%+blood+SFA%+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+MUFA%+blood+SFA%+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+Serine+blood+SFA%+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+Serine+blood+SFA%+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+Serine+blood+SFA%+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+L-Glutamine+blood+SFA%+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+L-Histidine+blood+SFA%+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Tryptophan+blood+MUFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+MUFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+MUFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+Serine+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+Serine+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+Serine+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+UFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+L-Glutamine+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
isocapric acid iso-C6+blood	PAI-1	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0458	5.10E-05	no	no	dn	up	up	up	HC
Bacteroides	PAI-1	Bacteroides-HDCA+stool+PAI-1	Indirect	Genus	DM-associated hormones	0.000267	5.10E-05	dn	dn	up	up	up	up	HC
Bacteroides	PAI-1	Bacteroides-Amyotrophic lateral sclerosis+PAI-1	Indirect	Genus	DM-associated hormones	0.000267	5.10E-05	dn	dn	up	up	up	up	HC
Bacteroides	PAI-1	Bacteroides-FGF basic+PAI-1	Indirect	Genus	DM-associated hormones	0.000267	5.10E-05	dn	dn	up	up	up	up	HC
Propionic acid+stool	PAI-1	Propionic acid+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.0436	5.10E-05	dn	no	up	up	up	up	HC
[Ruminococcus]	PAI-1	[Ruminococcus]-HDCA+stool+PAI-1	Indirect	Genus	DM-associated hormones	0.0679	5.10E-05	no	no	dn	up	up	up	HC
GUDCA+blood	PAI-1	GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0766	5.10E-05	no	no	dn	up	up	up	HC
GUDCA+blood	PAI-1	GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0766	5.10E-05	no	no	dn	up	up	up	HC
GUDCA+blood	PAI-1	GUDCA+blood-UFA%+blood+L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0766	5.10E-05	no	no	dn	up	up	up	HC
GUDCA+blood	PAI-1	GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0766	5.10E-05	no	no	dn	up	up	up	HC
GUDCA+blood	PAI-1	GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0766	5.10E-05	no	no	dn	up	up	up	HC
GUDCA+blood	PAI-1	GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0766	5.10E-05	no	no	dn	up	up	up	HC
GUDCA+blood	PAI-1	GUDCA+blood-PUFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0766	5.10E-05	no	no	dn	up	up	up	HC
GUDCA+blood	PAI-1	GUDCA+blood-UFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0766	5.10E-05	no	no	dn	up	up	up	HC
GUDCA+blood	PAI-1	GUDCA+blood-PUFA%+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0766	5.10E-05	no	no	dn	up	up	up	HC
GUDCA+blood	PAI-1	GUDCA+blood-PUFA/UFA+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0766	5.10E-05	no	no	dn	up	up	up	HC
GUDCA+blood	PAI-1	GUDCA+blood-iso-DCA+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.0766	5.10E-05	no	no	dn	up	up	up	HC
Acetic acid+stool	PAI-1	Acetic acid+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.0656	5.10E-05	dn	no	no	up	up	up	HC
Alistipes	PAI-1	Alistipes+PAI-1	Direct	Genus	DM-associated hormones	0.0114	5.10E-05	no	up	no	up	up	up	HC
Butyricimonas	PAI-1	Butyricimonas+18:1/18:1-PC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.17	5.10E-05	no	no	no	up	up	up	HC
Collinsella	PAI-1	Collinsella-L-Tryptophan+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.128	5.10E-05	no	no	no	up	up	up	HC
Collinsella	PAI-1	Collinsella-18:2-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.128	5.10E-05	no	no	no	up	up	up	HC
Collinsella	PAI-1	Collinsella-18:2/18:2-PC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.128	5.10E-05	no	no	no	up	up	up	HC
iso-DCA+stool	PAI-1	iso-DCA+stool-L-Tryptophan+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	HC
iso-DCA+stool	PAI-1	iso-DCA+stool+iso-LCA+stool-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	HC
iso-DCA+stool	PAI-1	iso-DCA+stool+LCA+stool-TCA+stool-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	HC
LCA+stool	PAI-1	LCA+stool-TCA+stool-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.314	5.10E-05	no	no	no	up	up	up	HC
Akkermansia	PAI-1	Akkermansia-Ribosome-Fc gamma R-mediated phagocytosis-PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	HC
Akkermansia	PAI-1	Akkermansia-Ribosome-Peroxisome-PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	HC
Akkermansia	PAI-1	Akkermansia-Wnt signaling pathway-GABAergic synapse-PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	HC
Akkermansia	PAI-1	Akkermansia-Ribosome-GABAergic synapse-PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	HC
Akkermansia	PAI-1	Akkermansia-Ribosome-Neutrophil extracellular trap formation-PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	HC
Akkermansia	PAI-1	Akkermansia-Wnt signaling pathway+Amyotrophic lateral sclerosis+PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	HC
Akkermansia	PAI-1	Akkermansia-Ribosome+Amyotrophic lateral sclerosis+PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	HC
Akkermansia	PAI-1	Akkermansia-Ribosome-Olfactory transduction-PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	HC
Akkermansia	PAI-1	Akkermansia-Wnt signaling pathway+C-peptide+PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	HC
Akkermansia	PAI-1	Akkermansia+Systemic lupus erythematosus-C-peptide+PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	HC
Akkermansia	PAI-1	Akkermansia-Acetic acid+stool+Homovanillic acid+urine-PAI-1	Indirect	Genus	DM-associated hormones	0.23	5.10E-05	no	no	no	up	up	up	HC
Bifidobacterium	PAI-1	Bifidobacterium+TXB2+blood-FGF basic+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	HC
Bifidobacterium	PAI-1	Bifidobacterium+AA+blood-FGF basic+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	HC
Bifidobacterium	PAI-1	Bifidobacterium-DCA+blood-C-peptide+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	HC
Bifidobacterium	PAI-1	Bifidobacterium-Intestinal immune network for IgA production+18:2/18:2-PC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	HC
Bifidobacterium	PAI-1	Bifidobacterium-Intestinal immune network for IgA production+18:1/18:1-PC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	HC
Bifidobacterium	PAI-1	Bifidobacterium-Intestinal immune network for IgA production-Olfactory transduction-PAI-1	Indirect	Genus	DM-associated hormones	0.105	5.10E-05	no	dn	no	up	up	up	HC
Phenylacetyl L-GlutaMine+urine	PAI-1	Phenylacetyl L-GlutaMine+urine+PAI-1	Direct	urine_cometabolism	DM-associated hormones	0.0909	5.10E-05	up	no	no	up	up	up	HC
Ruminococcus	PAI-1	Ruminococcus+PAI-1	Direct	Genus	DM-associated hormones	0.335	5.10E-05	no	no	no	up	up	up	HC
GCDCA+blood	PAI-1	GCDCA+blood-iso-DCA+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.31	5.10E-05	no	no	no	up	up	up	HC
GCDCA+blood	PAI-1	GCDCA+blood-MUFA%+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.31	5.10E-05	no	no	no	up	up	up	HC
GCDCA+blood	PAI-1	GCDCA+blood-PUFA%+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.31	5.10E-05	no	no	no	up	up	up	HC
GCDCA+blood	PAI-1	GCDCA+blood-iso-DCA+blood+L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.31	5.10E-05	no	no	no	up	up	up	HC
GCDCA+blood	PAI-1	GCDCA+blood-UFA%+blood+L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.31	5.10E-05	no	no	no	up	up	up	HC
GCDCA+blood	PAI-1	GCDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.31	5.10E-05	no	no	no	up	up	up	HC
GCDCA+blood	PAI-1	GCDCA+blood-PUFA%+blood+L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.31	5.10E-05	no	no	no	up	up	up	HC
GCDCA+blood	PAI-1	GCDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.31	5.10E-05	no	no	no	up	up	up	HC
GCDCA+blood	PAI-1	GCDCA+blood-UFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.31	5.10E-05	no	no	no	up	up	up	HC
GCDCA+blood	PAI-1	GCDCA+blood-MUFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.31	5.10E-05	no	no	no	up	up	up	HC
GCDCA+blood	PAI-1	GCDCA+blood-PUFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.31	5.10E-05	no	no	no	up	up	up	HC
[Prevotella]	PAI-1	[Prevotella]-18:0/22:6-PC+blood-20:0+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.367	5.10E-05	no	no	no	up	up	up	HC
[Prevotella]	PAI-1	"[Prevotella]-Growth hormone synthesis, secretion and action+C-peptide+PAI-1"	Indirect	Genus	DM-associated hormones	0.367	5.10E-05	no	no	no	up	up	up	HC
[Prevotella]	PAI-1	[Prevotella]-Aldosterone synthesis and secretion+C-peptide+PAI-1	Indirect	Genus	DM-associated hormones	0.367	5.10E-05	no	no	no	up	up	up	HC
[Prevotella]	PAI-1	[Prevotella]-GnRH signaling pathway+C-peptide+PAI-1	Indirect	Genus	DM-associated hormones	0.367	5.10E-05	no	no	no	up	up	up	HC
[Prevotella]	PAI-1	[Prevotella]-ACA+stool+C-peptide+PAI-1	Indirect	Genus	DM-associated hormones	0.367	5.10E-05	no	no	no	up	up	up	HC
[Prevotella]	PAI-1	[Prevotella]-Gap junction+C-peptide+PAI-1	Indirect	Genus	DM-associated hormones	0.367	5.10E-05	no	no	no	up	up	up	HC
[Prevotella]	PAI-1	[Prevotella]-Morphine addiction+C-peptide+PAI-1	Indirect	Genus	DM-associated hormones	0.367	5.10E-05	no	no	no	up	up	up	HC
[Prevotella]	PAI-1	[Prevotella]-18:0/22:6-PC+blood+Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.367	5.10E-05	no	no	no	up	up	up	HC
[Prevotella]	PAI-1	[Prevotella]-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis+PAI-1	Indirect	Genus	DM-associated hormones	0.367	5.10E-05	no	no	no	up	up	up	HC
[Prevotella]	PAI-1	[Prevotella]-GnRH signaling pathway+Amyotrophic lateral sclerosis+PAI-1	Indirect	Genus	DM-associated hormones	0.367	5.10E-05	no	no	no	up	up	up	HC
[Prevotella]	PAI-1	[Prevotella]+Ethanolamine+blood+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.367	5.10E-05	no	no	no	up	up	up	HC
[Prevotella]	PAI-1	[Prevotella]+Taurine+blood+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.367	5.10E-05	no	no	no	up	up	up	HC
[Prevotella]	PAI-1	[Prevotella]-18:0/22:6-PC+blood+22:6n3+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.367	5.10E-05	no	no	no	up	up	up	HC
ACA+blood	PAI-1	ACA+blood-TUDCA+blood-L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.338	5.10E-05	no	no	no	up	up	up	HC
ACA+blood	PAI-1	ACA+blood-P-hydroxyhippuric acid+urine-FGF basic+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.338	5.10E-05	no	no	no	up	up	up	HC
ACA+blood	PAI-1	ACA+blood-P-hydroxyhippuric acid+urine+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.338	5.10E-05	no	no	no	up	up	up	HC
DCA+stool	PAI-1	DCA+stool-DL-methionine sulfoxide+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.195	5.10E-05	no	no	no	up	up	up	HC
2-hydroxyhippuric acid+urine	PAI-1	2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.215	5.10E-05	no	no	no	up	up	up	HC
Butyric acid+stool	PAI-1	Butyric acid+stool+HDCA+stool+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.102	5.10E-05	dn	no	no	up	up	up	HC
4-hydroxybenzoic acid+stool	PAI-1	4-hydroxybenzoic acid+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.0536	5.10E-05	no	dn	no	up	up	up	HC
GCA+blood	PAI-1	GCA+blood-iso-DCA+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.16	5.10E-05	no	no	no	up	up	up	HC
GCA+blood	PAI-1	GCA+blood-iso-DCA+blood+L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.16	5.10E-05	no	no	no	up	up	up	HC
GCA+blood	PAI-1	GCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.16	5.10E-05	no	no	no	up	up	up	HC
GCA+blood	PAI-1	GCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.16	5.10E-05	no	no	no	up	up	up	HC
ACA+stool	PAI-1	ACA+stool+C-peptide+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.417	5.10E-05	no	no	no	up	up	up	HC
CDCA+blood	PAI-1	CDCA+blood-Creatinine+blood-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.506	5.10E-05	no	no	no	up	up	up	HC
CDCA+blood	PAI-1	CDCA+blood-d18:1-18:0-SM+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.506	5.10E-05	no	no	no	up	up	up	HC
CDCA+blood	PAI-1	CDCA+blood+DCA+blood-C-peptide+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.506	5.10E-05	no	no	no	up	up	up	HC
CDCA+blood	PAI-1	CDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.506	5.10E-05	no	no	no	up	up	up	HC
capric acid C6+blood	PAI-1	capric acid C6+blood-Cystine+blood+UFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.433	5.10E-05	no	no	no	up	up	up	HC
capric acid C6+blood	PAI-1	capric acid C6+blood-Cystine+blood+Serine+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.433	5.10E-05	no	no	no	up	up	up	HC
capric acid C6+blood	PAI-1	capric acid C6+blood-Cystine+blood+MUFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.433	5.10E-05	no	no	no	up	up	up	HC
capric acid C6+blood	PAI-1	capric acid C6+blood-Cystine+blood+L-Glutamine+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.433	5.10E-05	no	no	no	up	up	up	HC
capric acid C6+blood	PAI-1	capric acid C6+blood-Cystine+blood+UFA%+blood+L-Tryptophan+urine+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.433	5.10E-05	no	no	no	up	up	up	HC
capric acid C6+blood	PAI-1	capric acid C6+blood-Cystine+blood+Serine+blood+SFA%+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.433	5.10E-05	no	no	no	up	up	up	HC
capric acid C6+blood	PAI-1	capric acid C6+blood-Cystine+blood+MUFA%+blood+SFA%+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.433	5.10E-05	no	no	no	up	up	up	HC
capric acid C6+blood	PAI-1	capric acid C6+blood-Cystine+blood+L-Aspartic acid+blood+SFA%+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.433	5.10E-05	no	no	no	up	up	up	HC
capric acid C6+blood	PAI-1	capric acid C6+blood-Cystine+blood+L-Glutamine+blood+SFA%+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.433	5.10E-05	no	no	no	up	up	up	HC
Prevotella	PAI-1	Prevotella-18:1/18:1-PC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.287	5.10E-05	no	no	no	up	up	up	HC
Prevotella	PAI-1	Prevotella-SFA%+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.287	5.10E-05	no	no	no	up	up	up	HC
TCA+blood	PAI-1	TCA+blood+TUDCA+blood-L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.339	5.10E-05	no	no	no	up	up	up	HC
TCA+blood	PAI-1	TCA+blood+P-hydroxyhippuric acid+urine-FGF basic+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.339	5.10E-05	no	no	no	up	up	up	HC
TCA+blood	PAI-1	TCA+blood+P-hydroxyhippuric acid+urine+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.339	5.10E-05	no	no	no	up	up	up	HC
iso-DCA+blood	PAI-1	iso-DCA+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.38	5.10E-05	no	no	no	up	up	up	HC
iso-DCA+blood	PAI-1	iso-DCA+blood+L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.38	5.10E-05	no	no	no	up	up	up	HC
HCA+stool	PAI-1	HCA+stool-L-Homocystine+blood+FGF basic+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	HC
HCA+stool	PAI-1	HCA+stool-iso-LCA+stool-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	HC
HCA+stool	PAI-1	HCA+stool+16:0/18:3-PC+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.155	5.10E-05	no	no	no	up	up	up	HC
Roseburia	PAI-1	Roseburia-Neurotrophin signaling pathway+Amyotrophic lateral sclerosis+PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	HC
Roseburia	PAI-1	Roseburia-Transcriptional misregulation in cancer-HDCA+stool+PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	HC
Roseburia	PAI-1	Roseburia-RIG-I-like receptor signaling pathway-HDCA+stool+PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	HC
Roseburia	PAI-1	Roseburia-Hepatitis B-HDCA+stool+PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	HC
Roseburia	PAI-1	Roseburia-NF-kappa B signaling pathway-HDCA+stool+PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	HC
Roseburia	PAI-1	Roseburia-ACA+stool+C-peptide+PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	HC
Roseburia	PAI-1	Roseburia-L-Homocystine+blood+FGF basic+PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	HC
Roseburia	PAI-1	Roseburia+TXB2+blood-FGF basic+PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	HC
Roseburia	PAI-1	Roseburia-Spliceosome-Neutrophil extracellular trap formation-PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	HC
Roseburia	PAI-1	Roseburia-Transcriptional misregulation in cancer-Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	HC
Roseburia	PAI-1	Roseburia-RIG-I-like receptor signaling pathway+GABAergic synapse-PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	HC
Roseburia	PAI-1	Roseburia-NF-kappa B signaling pathway+Peroxisome-PAI-1	Indirect	Genus	DM-associated hormones	0.495	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+stool	PAI-1	12-ketoDCA+stool+LCA+stool-TCA+stool-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.505	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+stool	PAI-1	12-ketoDCA+stool-CDCA+stool+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.505	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+stool	PAI-1	12-ketoDCA+stool-TUDCA+blood-L-Tryptophan+urine+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.505	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+stool	PAI-1	12-ketoDCA+stool+DCA+stool-DL-methionine sulfoxide+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.505	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+stool	PAI-1	12-ketoDCA+stool-CA+stool-HDCA+stool+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.505	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+stool	PAI-1	12-ketoDCA+stool-CDCA+stool-HDCA+stool+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.505	5.10E-05	no	no	no	up	up	up	HC
GLCA+blood	PAI-1	GLCA+blood+L-Glutamine+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.319	5.10E-05	no	no	no	up	up	up	HC
GLCA+blood	PAI-1	GLCA+blood+L-Glutamine+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.319	5.10E-05	no	no	no	up	up	up	HC
L-Tryptophan+stool	PAI-1	L-Tryptophan+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.557	5.10E-05	no	no	no	up	up	up	HC
CA+blood	PAI-1	CA+blood+CDCA+blood-d18:1-18:0-SM+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	HC
CA+blood	PAI-1	CA+blood-MUFA+blood+MUFA%+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	HC
CA+blood	PAI-1	CA+blood+HCA+blood-MUFA%+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	HC
CA+blood	PAI-1	CA+blood-MUFA+blood-PUFA/MUFA+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	HC
CA+blood	PAI-1	CA+blood+LCA+blood-P-hydroxyhippuric acid+urine+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	HC
CA+blood	PAI-1	CA+blood+LCA+blood-n3+blood+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	HC
CA+blood	PAI-1	CA+blood+CDCA+blood-Creatinine+blood-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	HC
CA+blood	PAI-1	CA+blood-MUFA+blood+MUFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	HC
CA+blood	PAI-1	CA+blood+HCA+blood-MUFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	HC
CA+blood	PAI-1	CA+blood-MUFA+blood-PUFA/MUFA+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	HC
CA+blood	PAI-1	CA+blood+CDCA+blood+DCA+blood-C-peptide+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	HC
CA+blood	PAI-1	CA+blood+LCA+blood-TUDCA+blood-L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	HC
CA+blood	PAI-1	CA+blood+CDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	HC
CA+blood	PAI-1	CA+blood+HCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	HC
CA+blood	PAI-1	CA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.606	5.10E-05	no	no	no	up	up	up	HC
GUDCA+stool	PAI-1	GUDCA+stool+Phenylacetic acid+stool-Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0085	5.10E-05	no	dn	no	up	up	up	HC
GUDCA+stool	PAI-1	GUDCA+stool+Phenylacetic acid+stool-22:6n3+blood-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0085	5.10E-05	no	dn	no	up	up	up	HC
GUDCA+stool	PAI-1	GUDCA+stool+Phenylacetic acid+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0085	5.10E-05	no	dn	no	up	up	up	HC
GUDCA+stool	PAI-1	GUDCA+stool+L-Tryptophan+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0085	5.10E-05	no	dn	no	up	up	up	HC
GUDCA+stool	PAI-1	GUDCA+stool+Phenylacetic acid+stool-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0085	5.10E-05	no	dn	no	up	up	up	HC
GUDCA+stool	PAI-1	GUDCA+stool+Phenylacetic acid+stool+20:0+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0085	5.10E-05	no	dn	no	up	up	up	HC
GUDCA+stool	PAI-1	GUDCA+stool+Phenylacetic acid+stool+18:2/18:2-PC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0085	5.10E-05	no	dn	no	up	up	up	HC
L-Phenylalanine+stool	PAI-1	L-Phenylalanine+stool-Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.398	5.10E-05	no	no	no	up	up	up	HC
L-Phenylalanine+stool	PAI-1	L-Phenylalanine+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.398	5.10E-05	no	no	no	up	up	up	HC
butyric acid C4+blood	PAI-1	butyric acid C4+blood-DCA+blood-C-peptide+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.407	5.10E-05	no	no	no	up	up	up	HC
GCA+stool	PAI-1	GCA+stool+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0809	5.10E-05	no	no	no	up	up	up	HC
Coprococcus	PAI-1	Coprococcus+TCA+stool-PAI-1	Indirect	Genus	DM-associated hormones	0.612	5.10E-05	no	no	no	up	up	up	HC
Coprococcus	PAI-1	Coprococcus+Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.612	5.10E-05	no	no	no	up	up	up	HC
Coprococcus	PAI-1	Coprococcus+Lachnospira-PAI-1	Indirect	Genus	DM-associated hormones	0.612	5.10E-05	no	no	no	up	up	up	HC
Coprococcus	PAI-1	Coprococcus-Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.612	5.10E-05	no	no	no	up	up	up	HC
Coprococcus	PAI-1	Coprococcus+Homovanillic acid+urine-PAI-1	Indirect	Genus	DM-associated hormones	0.612	5.10E-05	no	no	no	up	up	up	HC
Coprococcus	PAI-1	Coprococcus-18:2-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.612	5.10E-05	no	no	no	up	up	up	HC
Oscillospira	PAI-1	Oscillospira-Homovanillic acid+urine-PAI-1	Indirect	Genus	DM-associated hormones	0.62	5.10E-05	no	no	no	up	up	up	HC
Oscillospira	PAI-1	Oscillospira+C-peptide+PAI-1	Indirect	Genus	DM-associated hormones	0.62	5.10E-05	no	no	no	up	up	up	HC
HCA+blood	PAI-1	HCA+blood-MUFA%+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.544	5.10E-05	no	no	no	up	up	up	HC
HCA+blood	PAI-1	HCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.544	5.10E-05	no	no	no	up	up	up	HC
HCA+blood	PAI-1	HCA+blood-MUFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.544	5.10E-05	no	no	no	up	up	up	HC
iso-LCA+stool	PAI-1	iso-LCA+stool-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.72	5.10E-05	no	no	no	up	up	up	HC
2-methyl-butyric acid m-C4+blood	PAI-1	2-methyl-butyric acid m-C4+blood+20:1+blood-22:6n3+blood-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.262	5.10E-05	no	no	no	up	up	up	HC
DCA+blood	PAI-1	DCA+blood-C-peptide+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.122	5.10E-05	no	no	no	up	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool+20:3n6+blood-Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/22:6-PC+blood+Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool+14:0/18:2-PC+blood+Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine+Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool-Hypotaurine+blood-Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool+20:2/18:0-PC+blood+Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/22:6-PC+blood-20:0+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool-Glycine+blood+SFA%+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/22:6-PC+blood+22:6n3+blood-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool+14:0/18:2-PC+blood+22:6n3+blood-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/20:3-PC+blood+22:6n3+blood-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool+14:0+blood+22:6n3+blood-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool+20:2/18:0-PC+blood+22:6n3+blood-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	PAI-1	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0+blood+22:6n3+blood-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.33	5.10E-05	no	no	no	up	up	up	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	PAI-1	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine+Leptin-PAI-1"	Indirect	urine_cometabolism	DM-associated hormones	0.0125	5.10E-05	up	up	no	up	up	up	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	PAI-1	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+PAI-1"	Indirect	urine_cometabolism	DM-associated hormones	0.0125	5.10E-05	up	up	no	up	up	up	HC
GLCA+stool	PAI-1	GLCA+stool-iso-LCA+stool-Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.617	5.10E-05	no	no	no	up	up	up	HC
GLCA+stool	PAI-1	GLCA+stool-LCA+stool-TCA+stool-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.617	5.10E-05	no	no	no	up	up	up	HC
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	HC
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	HC
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	HC
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	HC
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool+L-Tryptophan+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	HC
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+18:2/18:2-PC+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	HC
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+20:0+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	HC
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-22:6n3+blood-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	HC
Indole-3-Acetic acid+stool	PAI-1	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-Homovanillic acid+urine-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.304	5.10E-05	no	no	no	up	up	up	HC
TCA+stool	PAI-1	TCA+stool-PAI-1	Direct	stool_bileacids	DM-associated hormones	0.458	5.10E-05	no	no	no	up	up	up	HC
HDCA+stool	PAI-1	HDCA+stool+PAI-1	Direct	stool_bileacids	DM-associated hormones	0.176	5.10E-05	no	no	no	up	up	up	HC
Lachnospira	PAI-1	Lachnospira-PAI-1	Direct	Genus	DM-associated hormones	0.279	5.10E-05	no	no	no	up	up	up	HC
isobutyric acid C4+blood	PAI-1	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0151	5.10E-05	up	up	no	up	up	up	HC
isobutyric acid C4+blood	PAI-1	isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood-PUFA/MUFA+blood+SFA%+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0151	5.10E-05	up	up	no	up	up	up	HC
isobutyric acid C4+blood	PAI-1	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+Serine+blood+SFA%+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0151	5.10E-05	up	up	no	up	up	up	HC
isobutyric acid C4+blood	PAI-1	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+MUFA%+blood+SFA%+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0151	5.10E-05	up	up	no	up	up	up	HC
isobutyric acid C4+blood	PAI-1	isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood+MUFA%+blood+SFA%+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0151	5.10E-05	up	up	no	up	up	up	HC
isobutyric acid C4+blood	PAI-1	isobutyric acid C4+blood+L-Isoleucine+blood+L-Tryptophan+blood+MUFA%+blood+SFA%+blood+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0151	5.10E-05	up	up	no	up	up	up	HC
isobutyric acid C4+blood	PAI-1	isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood-PUFA/MUFA+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0151	5.10E-05	up	up	no	up	up	up	HC
isobutyric acid C4+blood	PAI-1	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+Serine+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0151	5.10E-05	up	up	no	up	up	up	HC
isobutyric acid C4+blood	PAI-1	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+MUFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0151	5.10E-05	up	up	no	up	up	up	HC
isobutyric acid C4+blood	PAI-1	isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood+MUFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0151	5.10E-05	up	up	no	up	up	up	HC
isobutyric acid C4+blood	PAI-1	isobutyric acid C4+blood+L-Isoleucine+blood+L-Tryptophan+blood+MUFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0151	5.10E-05	up	up	no	up	up	up	HC
isobutyric acid C4+blood	PAI-1	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.0151	5.10E-05	up	up	no	up	up	up	HC
GCDCA+stool	PAI-1	GCDCA+stool+C-peptide+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.0471	5.10E-05	no	dn	no	up	up	up	HC
5-Hydroxytryptamine+stool	PAI-1	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.00862	5.10E-05	dn	dn	no	up	up	up	HC
5-Hydroxytryptamine+stool	PAI-1	5-Hydroxytryptamine+stool+GCA+stool+Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.00862	5.10E-05	dn	dn	no	up	up	up	HC
5-Hydroxytryptamine+stool	PAI-1	5-Hydroxytryptamine+stool+GCDCA+stool+C-peptide+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.00862	5.10E-05	dn	dn	no	up	up	up	HC
Odoribacter	PAI-1	Odoribacter-C-peptide+PAI-1	Indirect	Genus	DM-associated hormones	0.798	5.10E-05	no	no	no	up	up	up	HC
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool+Phenylacetic acid+stool-Homovanillic acid+urine-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	HC
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool+Phenylacetic acid+stool-22:6n3+blood-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	HC
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool+Phenylacetic acid+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	HC
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool+Phenylacetic acid+stool-Leptin-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	HC
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	HC
Isobutyric acid+stool	PAI-1	Isobutyric acid+stool+Phenylacetic acid+stool+18:2/18:2-PC+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.408	5.10E-05	no	no	no	up	up	up	HC
2-hydroxyphenylacetic acid+urine	PAI-1	2-hydroxyphenylacetic acid+urine-Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.763	5.10E-05	no	no	no	up	up	up	HC
Kynurenic acid+stool	PAI-1	Kynurenic acid+stool-UDCA+stool+16:0/18:3-PC+blood+Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.037	5.10E-05	dn	dn	no	up	up	up	HC
Kynurenic acid+stool	PAI-1	Kynurenic acid+stool-nutriCA+stool+16:0/18:3-PC+blood+Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.037	5.10E-05	dn	dn	no	up	up	up	HC
Kynurenic acid+stool	PAI-1	Kynurenic acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.037	5.10E-05	dn	dn	no	up	up	up	HC
Kynurenic acid+stool	PAI-1	Kynurenic acid+stool-nutriCA+stool+TUDCA+blood-L-Tryptophan+urine+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.037	5.10E-05	dn	dn	no	up	up	up	HC
L-Tryptophan+urine	PAI-1	L-Tryptophan+urine+PAI-1	Direct	urine_cometabolism	DM-associated hormones	0.226	5.10E-05	no	no	no	up	up	up	HC
Eggerthella	PAI-1	Eggerthella+Bacteroides-FGF basic+PAI-1	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	HC
Eggerthella	PAI-1	Eggerthella+Bacteroides-HDCA+stool+PAI-1	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	HC
Eggerthella	PAI-1	Eggerthella+Clostridium-L-Tryptophan+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	HC
Eggerthella	PAI-1	Eggerthella+Clostridium+Peroxisome-PAI-1	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	HC
Eggerthella	PAI-1	Eggerthella+Bacteroides-Amyotrophic lateral sclerosis+PAI-1	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	HC
Eggerthella	PAI-1	Eggerthella-Faecalibacterium-Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.912	5.10E-05	no	no	no	up	up	up	HC
Anaerotruncus	PAI-1	Anaerotruncus-Gemmiger+DCA+stool-DL-methionine sulfoxide+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.904	5.10E-05	no	no	no	up	up	up	HC
Anaerotruncus	PAI-1	Anaerotruncus-Gemmiger-L-Phenylalanine+stool-Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.904	5.10E-05	no	no	no	up	up	up	HC
Anaerotruncus	PAI-1	Anaerotruncus-Gemmiger-L-Phenylalanine+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.904	5.10E-05	no	no	no	up	up	up	HC
Anaerotruncus	PAI-1	Anaerotruncus-Gemmiger-L-Tyrosine+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.904	5.10E-05	no	no	no	up	up	up	HC
Anaerotruncus	PAI-1	Anaerotruncus-Gemmiger-L-Tryptophan+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.904	5.10E-05	no	no	no	up	up	up	HC
Anaerotruncus	PAI-1	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.904	5.10E-05	no	no	no	up	up	up	HC
Anaerotruncus	PAI-1	Anaerotruncus-Gemmiger-TUDCA+blood-L-Tryptophan+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.904	5.10E-05	no	no	no	up	up	up	HC
Anaerostipes	PAI-1	Anaerostipes-C-peptide+PAI-1	Indirect	Genus	DM-associated hormones	0.568	5.10E-05	no	no	no	up	up	up	HC
Anaerostipes	PAI-1	Anaerostipes+TCA+stool-PAI-1	Indirect	Genus	DM-associated hormones	0.568	5.10E-05	no	no	no	up	up	up	HC
Anaerostipes	PAI-1	Anaerostipes-20:0+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.568	5.10E-05	no	no	no	up	up	up	HC
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+Phenylacetic acid+stool+18:2/18:2-PC+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	HC
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+Phenylacetic acid+stool-Homovanillic acid+urine-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	HC
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+Phenylacetic acid+stool-22:6n3+blood-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	HC
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+Phenylacetic acid+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	HC
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+Phenylacetic acid+stool-Leptin-PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	HC
Isovaleric acid+stool	PAI-1	Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+PAI-1	Indirect	stool_scfa	DM-associated hormones	0.343	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella+Glycolysis / Gluconeogenesis-cGMP-PKG signaling pathway-PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella+Carbon metabolism+Neutrophil extracellular trap formation-PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella-p53 signaling pathway-Neutrophil extracellular trap formation-PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella-Relaxin signaling pathway+20:0+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella-Relaxin signaling pathway+SFA%+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella+Carbon metabolism+Fc gamma R-mediated phagocytosis-PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella-Longevity regulating pathway-Fc gamma R-mediated phagocytosis-PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella+Carbon metabolism-Amyotrophic lateral sclerosis+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella-GnRH signaling pathway+Amyotrophic lateral sclerosis+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella+Glycolysis / Gluconeogenesis-Amyotrophic lateral sclerosis+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella-Relaxin signaling pathway+Amyotrophic lateral sclerosis+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella-Autophagy - animal+GABAergic synapse-PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	"Paraprevotella-Growth hormone synthesis, secretion and action+C-peptide+PAI-1"	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella-GnRH signaling pathway+C-peptide+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella-Chemical carcinogenesis - receptor activation+C-peptide+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella+Taurine+blood+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella-Autophagy - animal-Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella-L-Homocystine+blood+FGF basic+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Paraprevotella	PAI-1	Paraprevotella+AA+blood-FGF basic+PAI-1	Indirect	Genus	DM-associated hormones	0.118	5.10E-05	no	no	no	up	up	up	HC
Homovanillic acid+urine	PAI-1	Homovanillic acid+urine-PAI-1	Direct	urine_cometabolism	DM-associated hormones	0.45	5.10E-05	no	no	no	up	up	up	HC
TDCA+blood	PAI-1	TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.155	5.10E-05	no	up	no	up	up	up	HC
iso-LCA+blood	PAI-1	iso-LCA+blood-TUDCA+blood-L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.507	5.10E-05	no	no	no	up	up	up	HC
iso-LCA+blood	PAI-1	iso-LCA+blood-n3+blood+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.507	5.10E-05	no	no	no	up	up	up	HC
Phenaceturic acid+urine	PAI-1	Phenaceturic acid+urine+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.737	5.10E-05	no	no	no	up	up	up	HC
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool-LCA+stool-TCA+stool-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	HC
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool-Propionic acid+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	HC
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool-Acetic acid+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	HC
¦Ø-MCA+stool	PAI-1	¦Ø-MCA+stool-Butyric acid+stool+HDCA+stool+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.919	5.10E-05	no	no	no	up	up	up	HC
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool+18:2/18:2-PC+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	HC
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool-Homovanillic acid+urine-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	HC
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool-22:6n3+blood-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	HC
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	HC
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool-Leptin-PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	HC
Phenylacetic acid+stool	PAI-1	Phenylacetic acid+stool+20:0+blood+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.785	5.10E-05	no	no	no	up	up	up	HC
Gemmiger	PAI-1	Gemmiger+DCA+stool-DL-methionine sulfoxide+blood-PAI-1	Indirect	Genus	DM-associated hormones	0.595	5.10E-05	no	no	no	up	up	up	HC
Gemmiger	PAI-1	Gemmiger-L-Phenylalanine+stool-Leptin-PAI-1	Indirect	Genus	DM-associated hormones	0.595	5.10E-05	no	no	no	up	up	up	HC
Gemmiger	PAI-1	Gemmiger-L-Phenylalanine+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.595	5.10E-05	no	no	no	up	up	up	HC
Gemmiger	PAI-1	Gemmiger-L-Tyrosine+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.595	5.10E-05	no	no	no	up	up	up	HC
Gemmiger	PAI-1	Gemmiger-L-Tryptophan+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.595	5.10E-05	no	no	no	up	up	up	HC
Gemmiger	PAI-1	Gemmiger-Staphylococcus aureus infection+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.595	5.10E-05	no	no	no	up	up	up	HC
Gemmiger	PAI-1	Gemmiger-TUDCA+blood-L-Tryptophan+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.595	5.10E-05	no	no	no	up	up	up	HC
GDCA+stool	PAI-1	GDCA+stool-18:1/16:0-PC+blood+SFA%+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	HC
GDCA+stool	PAI-1	GDCA+stool-16:0/18:2-PC+blood+SFA%+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	HC
GDCA+stool	PAI-1	GDCA+stool-TXB2+blood-FGF basic+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	HC
GDCA+stool	PAI-1	GDCA+stool-18:1/16:0-PC+blood+18:1/18:1-PC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	HC
GDCA+stool	PAI-1	GDCA+stool-16:0/18:2-PC+blood+18:1/18:1-PC+blood+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	HC
GDCA+stool	PAI-1	GDCA+stool-18:1/16:0-PC+blood-Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	HC
GDCA+stool	PAI-1	GDCA+stool-16:0/18:2-PC+blood-Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	HC
GDCA+stool	PAI-1	GDCA+stool-Propionic acid+stool+Homovanillic acid+urine-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	HC
GDCA+stool	PAI-1	GDCA+stool-18:1/16:0-PC+blood+L-Tryptophan+urine+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	HC
GDCA+stool	PAI-1	GDCA+stool-16:0/18:2-PC+blood+L-Tryptophan+urine+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	HC
GDCA+stool	PAI-1	GDCA+stool-18:1/16:0-PC+blood+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	HC
GDCA+stool	PAI-1	GDCA+stool-16:0/18:2-PC+blood+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.656	5.10E-05	no	no	no	up	up	up	HC
L-Tyrosine+stool	PAI-1	L-Tyrosine+stool+Phenylacetyl L-GlutaMine+urine+PAI-1	Indirect	stool_cometabolism	DM-associated hormones	0.44	5.10E-05	no	no	no	up	up	up	HC
CDCA+stool	PAI-1	CDCA+stool+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.663	5.10E-05	no	no	no	up	up	up	HC
CDCA+stool	PAI-1	CDCA+stool-HDCA+stool+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.663	5.10E-05	no	no	no	up	up	up	HC
CA+stool	PAI-1	CA+stool-HDCA+stool+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.827	5.10E-05	no	no	no	up	up	up	HC
HDCA+blood	PAI-1	HDCA+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.483	5.10E-05	no	no	no	up	up	up	HC
UDCA+stool	PAI-1	UDCA+stool+16:0/18:3-PC+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.266	5.10E-05	no	no	no	up	up	up	HC
LCA+blood	PAI-1	LCA+blood-TUDCA+blood-L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.884	5.10E-05	no	no	no	up	up	up	HC
LCA+blood	PAI-1	LCA+blood-P-hydroxyhippuric acid+urine+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.884	5.10E-05	no	no	no	up	up	up	HC
LCA+blood	PAI-1	LCA+blood-n3+blood+Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.884	5.10E-05	no	no	no	up	up	up	HC
LCA+blood	PAI-1	LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.884	5.10E-05	no	no	no	up	up	up	HC
nutriCA+stool	PAI-1	nutriCA+stool-L-Homocystine+blood+FGF basic+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.481	5.10E-05	no	no	no	up	up	up	HC
nutriCA+stool	PAI-1	nutriCA+stool+TUDCA+blood-L-Tryptophan+urine+PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.481	5.10E-05	no	no	no	up	up	up	HC
nutriCA+stool	PAI-1	nutriCA+stool+16:0/18:3-PC+blood+Leptin-PAI-1	Indirect	stool_bileacids	DM-associated hormones	0.481	5.10E-05	no	no	no	up	up	up	HC
GDCA+blood	PAI-1	GDCA+blood+TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.632	5.10E-05	no	no	no	up	up	up	HC
P-hydroxyhippuric acid+urine	PAI-1	P-hydroxyhippuric acid+urine+Leptin-PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.436	5.10E-05	no	no	no	up	up	up	HC
P-hydroxyhippuric acid+urine	PAI-1	P-hydroxyhippuric acid+urine-FGF basic+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.436	5.10E-05	no	no	no	up	up	up	HC
acetic acid C2+blood	PAI-1	acetic acid C2+blood+n3+blood+Leptin-PAI-1	Indirect	serum_scfa	DM-associated hormones	0.000193	5.10E-05	up	dn	no	up	up	up	HC
isovaleric acid iso-C5+blood	PAI-1	isovaleric acid iso-C5+blood+Sarcosine+blood-L-Phenylalanine+urine+L-Tryptophan+urine+PAI-1	Indirect	serum_scfa	DM-associated hormones	0.117	5.10E-05	no	no	no	up	up	up	HC
L-Phenylalanine+urine	PAI-1	L-Phenylalanine+urine+L-Tryptophan+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.0908	5.10E-05	no	up	no	up	up	up	HC
Clostridium	PAI-1	Clostridium+Peroxisome-PAI-1	Indirect	Genus	DM-associated hormones	0.925	5.10E-05	no	no	no	up	up	up	HC
Clostridium	PAI-1	Clostridium-L-Tryptophan+urine+PAI-1	Indirect	Genus	DM-associated hormones	0.925	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:1-LPC+blood+18:2-LPC+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood+14:0/16:0-PC+blood-18:2/18:2-PC+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:1-LPC+blood+18:2/18:2-PC+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:2/18:1-PC+blood+18:2/18:2-PC+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:2/16:0-PC+blood+18:2/18:2-PC+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:1-LPC+blood-22:6n3+blood-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:2/18:1-PC+blood-22:6n3+blood-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:1-LPC+blood-Leptin-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-UFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-MUFA%+blood-Homovanillic acid+urine-PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:1-LPC+blood+20:0+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:2/18:1-PC+blood+20:0+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-iso-DCA+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood+16:0/16:1-PI+blood-SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-MUFA%+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:2/16:0-PC+blood+SFA%+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-iso-DCA+blood+L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:1-LPC+blood+L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-UFA%+blood+L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-18:2/16:0-PC+blood+L-Tryptophan+urine+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood+DCA+blood-C-peptide+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood+16:0/16:1-PI+blood-18:1/18:1-PC+blood+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
12-ketoDCA+blood	PAI-1	12-ketoDCA+blood-AA+blood-FGF basic+PAI-1	Indirect	serum_bileacids	DM-associated hormones	0.517	5.10E-05	no	no	no	up	up	up	HC
Butyricicoccus	PAI-1	Butyricicoccus-18:2-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.852	5.10E-05	no	no	no	up	up	up	HC
3-Hydroxy-L-kynurenine+urine	PAI-1	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine+PAI-1	Indirect	urine_cometabolism	DM-associated hormones	0.401	5.10E-05	no	no	no	up	up	up	HC
Wautersiella	PAI-1	Wautersiella+Butyricicoccus-18:2-LPC+blood+PAI-1	Indirect	Genus	DM-associated hormones	0.289	5.10E-05	no	no	no	up	up	up	HC
Blautia	MCP-1(MCAF)	Blautia-Butyric acid+stool+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	HC
Blautia	MCP-1(MCAF)	Blautia-ACA+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	1.36E-05	0.0633	up	dn	dn	dn	no	up	HC
Parabacteroides	MCP-1(MCAF)	Parabacteroides+MCP-1(MCAF)	Direct	Genus	serum_cytokines	4.19E-05	0.0633	no	up	up	dn	no	up	HC
Dorea	MCP-1(MCAF)	Dorea-Endocrine resistance+Mineral absorption+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.00362	0.0633	up	no	dn	dn	no	up	HC
Dorea	MCP-1(MCAF)	Dorea-GnRH signaling pathway+Mineral absorption+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.00362	0.0633	up	no	dn	dn	no	up	HC
Dorea	MCP-1(MCAF)	Dorea-Endocrine resistance+Necroptosis+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.00362	0.0633	up	no	dn	dn	no	up	HC
Dorea	MCP-1(MCAF)	Dorea-Thyroid hormone signaling pathway+Ethanolamine+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.00362	0.0633	up	no	dn	dn	no	up	HC
Dorea	MCP-1(MCAF)	Dorea-Amphetamine addiction+HDCA+stool+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.00362	0.0633	up	no	dn	dn	no	up	HC
Dorea	MCP-1(MCAF)	Dorea+CDCA+stool-HDCA+stool+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.00362	0.0633	up	no	dn	dn	no	up	HC
Dorea	MCP-1(MCAF)	Dorea-LCA+stool+18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.00362	0.0633	up	no	dn	dn	no	up	HC
Dorea	MCP-1(MCAF)	Dorea-LCA+stool+16:0/18:2-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.00362	0.0633	up	no	dn	dn	no	up	HC
Dorea	MCP-1(MCAF)	Dorea+Legionellosis+d18:1-14:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.00362	0.0633	up	no	dn	dn	no	up	HC
Dorea	MCP-1(MCAF)	Dorea-18:2-LPC+blood-d18:1-14:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.00362	0.0633	up	no	dn	dn	no	up	HC
Dorea	MCP-1(MCAF)	Dorea+16:0/18:3-PC+blood+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.00362	0.0633	up	no	dn	dn	no	up	HC
Dorea	MCP-1(MCAF)	"Dorea-Growth hormone synthesis, secretion and action-d18:1-20:0-SM+blood-MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.00362	0.0633	up	no	dn	dn	no	up	HC
Faecalibacterium	MCP-1(MCAF)	Faecalibacterium+Butyric acid+stool+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0039	0.0633	no	dn	dn	dn	no	up	HC
isocapric acid iso-C6+blood	MCP-1(MCAF)	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood-IL-9-MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.0458	0.0633	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	MCP-1(MCAF)	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood-IL-9-MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.0458	0.0633	no	no	dn	dn	no	up	HC
isocapric acid iso-C6+blood	MCP-1(MCAF)	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-IL-9-MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.0458	0.0633	no	no	dn	dn	no	up	HC
Bacteroides	MCP-1(MCAF)	Bacteroides-HDCA+stool+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	HC
Bacteroides	MCP-1(MCAF)	Bacteroides+DL-Indole-3-lactic acid+urine-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.000267	0.0633	dn	dn	up	dn	no	up	HC
Propionic acid+stool	MCP-1(MCAF)	Propionic acid+stool+MCP-1(MCAF)	Direct	stool_scfa	serum_cytokines	0.0436	0.0633	dn	no	up	dn	no	up	HC
[Ruminococcus]	MCP-1(MCAF)	[Ruminococcus]-HDCA+stool+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0679	0.0633	no	no	dn	dn	no	up	HC
[Ruminococcus]	MCP-1(MCAF)	[Ruminococcus]+IL-9-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0679	0.0633	no	no	dn	dn	no	up	HC
GUDCA+blood	MCP-1(MCAF)	GUDCA+blood-iso-DCA+blood+L-Histidine+blood+L-Methionine+blood-IL-9-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0633	no	no	dn	dn	no	up	HC
GUDCA+blood	MCP-1(MCAF)	GUDCA+blood-iso-DCA+blood+L-Histidine+blood+L-Lysine+blood-IL-9-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0633	no	no	dn	dn	no	up	HC
Acetic acid+stool	MCP-1(MCAF)	Acetic acid+stool+MCP-1(MCAF)	Direct	stool_scfa	serum_cytokines	0.0656	0.0633	dn	no	no	dn	no	up	HC
Alistipes	MCP-1(MCAF)	Alistipes+20:3/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0114	0.0633	no	up	no	dn	no	up	HC
Alistipes	MCP-1(MCAF)	Alistipes+Ethanolamine+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0114	0.0633	no	up	no	dn	no	up	HC
Alistipes	MCP-1(MCAF)	Alistipes+16:0/18:2-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0114	0.0633	no	up	no	dn	no	up	HC
Alistipes	MCP-1(MCAF)	Alistipes+18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.0114	0.0633	no	up	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas-Leishmaniasis+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Long-term depression-d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas-Leishmaniasis+d18:1-14:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Amoebiasis-d18:1-14:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Morphine addiction-d18:1-14:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Long-term depression-d18:1-14:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+16:0/20:3-PC+blood+16:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Prevotella-16:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+16:0/20:3-PC+blood+20:3/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+18:1/18:1-PC+blood+20:3/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas-Glutathione metabolism+AMPK signaling pathway+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas-Glutathione metabolism+Malaria+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+16:0/20:3-PC+blood+18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas-Glutathione metabolism-NF-kappa B signaling pathway-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas-Glutathione metabolism+Necroptosis+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas-Glutathione metabolism-T cell receptor signaling pathway-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas-Eotaxin-IL-9-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+L-Methionine+blood-IL-9-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Amoebiasis-Acetic acid+stool+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Phospholipase D signaling pathway-Acetic acid+stool+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Spinocerebellar ataxia-Ethanolamine+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Morphine addiction+ACA+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+18:1/18:1-PC+blood+ACA+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Spinocerebellar ataxia+Measles-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas-Glutathione metabolism-Measles-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Neurotrophin signaling pathway+Measles-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Chagas disease+Measles-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+16:0/20:3-PC+blood-d18:1-16:1-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+cAMP signaling pathway-Hematopoietic cell lineage+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+cAMP signaling pathway+Mineral absorption+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Adrenergic signaling in cardiomyocytes+Mineral absorption+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas-Glutathione metabolism+Mineral absorption+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Inflammatory mediator regulation of TRP channels+Mineral absorption+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Calcium signaling pathway+Mineral absorption+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Dopaminergic synapse+Mineral absorption+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Long-term depression+Mineral absorption+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Non-alcoholic fatty liver disease+Mineral absorption+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	"Butyricimonas+Parathyroid hormone synthesis, secretion and action+Mineral absorption+MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Pancreatic secretion+Mineral absorption+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Prevotella-L-Tryptophan+stool-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Phospholipase D signaling pathway+L-Tryptophan+stool-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Butyricimonas	MCP-1(MCAF)	Butyricimonas+Prevotella-24:1+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.17	0.0633	no	no	no	dn	no	up	HC
Collinsella	MCP-1(MCAF)	Collinsella+Porphyrin and chlorophyll metabolism+Malaria+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	HC
Collinsella	MCP-1(MCAF)	"Collinsella+Glycine, serine and threonine metabolism-Measles-MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	HC
Collinsella	MCP-1(MCAF)	Collinsella+Porphyrin and chlorophyll metabolism+Mineral absorption+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	HC
Collinsella	MCP-1(MCAF)	Collinsella+Porphyrin and chlorophyll metabolism+Necroptosis+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	HC
Collinsella	MCP-1(MCAF)	Collinsella+Porphyrin and chlorophyll metabolism-NF-kappa B signaling pathway-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	HC
Collinsella	MCP-1(MCAF)	"Collinsella+Glycine, serine and threonine metabolism-NF-kappa B signaling pathway-MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	HC
Collinsella	MCP-1(MCAF)	Collinsella+Porphyrin and chlorophyll metabolism+Acetic acid+stool+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	HC
Collinsella	MCP-1(MCAF)	Collinsella+Porphyrin and chlorophyll metabolism+AMPK signaling pathway+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	HC
Collinsella	MCP-1(MCAF)	"Collinsella+Glycine, serine and threonine metabolism+AMPK signaling pathway+MCP-1(MCAF)"	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	HC
Collinsella	MCP-1(MCAF)	Collinsella+18:0/18:0-PS+blood+d18:1-14:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	HC
Collinsella	MCP-1(MCAF)	Collinsella-18:2-LPC+blood-d18:1-14:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.128	0.0633	no	no	no	dn	no	up	HC
iso-DCA+stool	MCP-1(MCAF)	iso-DCA+stool-L-Tryptophan+stool-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.155	0.0633	no	no	no	dn	no	up	HC
LCA+stool	MCP-1(MCAF)	LCA+stool+16:0/18:2-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.314	0.0633	no	no	no	dn	no	up	HC
LCA+stool	MCP-1(MCAF)	LCA+stool+18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.314	0.0633	no	no	no	dn	no	up	HC
Akkermansia	MCP-1(MCAF)	Akkermansia-Acetic acid+stool+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.23	0.0633	no	no	no	dn	no	up	HC
Akkermansia	MCP-1(MCAF)	Akkermansia+d18:1-22:1-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.23	0.0633	no	no	no	dn	no	up	HC
Bifidobacterium	MCP-1(MCAF)	Bifidobacterium+d18:1-14:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.105	0.0633	no	dn	no	dn	no	up	HC
Ruminococcus	MCP-1(MCAF)	Ruminococcus+HDCA+stool+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.335	0.0633	no	no	no	dn	no	up	HC
GCDCA+blood	MCP-1(MCAF)	GCDCA+blood+L-Alanine+blood+L-Asparagine+blood+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.31	0.0633	no	no	no	dn	no	up	HC
GCDCA+blood	MCP-1(MCAF)	GCDCA+blood+L-Alanine+blood-IL-9-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.31	0.0633	no	no	no	dn	no	up	HC
[Prevotella]	MCP-1(MCAF)	[Prevotella]+Ethanolamine+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.367	0.0633	no	no	no	dn	no	up	HC
ACA+blood	MCP-1(MCAF)	ACA+blood+MCP-1(MCAF)	Direct	serum_bileacids	serum_cytokines	0.338	0.0633	no	no	no	dn	no	up	HC
DCA+stool	MCP-1(MCAF)	DCA+stool-L-Tryptophan+stool-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.195	0.0633	no	no	no	dn	no	up	HC
Butyric acid+stool	MCP-1(MCAF)	Butyric acid+stool+MCP-1(MCAF)	Direct	stool_scfa	serum_cytokines	0.102	0.0633	dn	no	no	dn	no	up	HC
4-hydroxybenzoic acid+stool	MCP-1(MCAF)	4-hydroxybenzoic acid+stool+Acetic acid+stool+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.0633	no	dn	no	dn	no	up	HC
GCA+blood	MCP-1(MCAF)	GCA+blood+L-Alanine+blood+L-Asparagine+blood+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.16	0.0633	no	no	no	dn	no	up	HC
GCA+blood	MCP-1(MCAF)	GCA+blood+L-Alanine+blood-IL-9-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.16	0.0633	no	no	no	dn	no	up	HC
ACA+stool	MCP-1(MCAF)	ACA+stool-Acetic acid+stool+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.417	0.0633	no	no	no	dn	no	up	HC
CDCA+blood	MCP-1(MCAF)	CDCA+blood-Creatinine+blood+L-Asparagine+blood+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.506	0.0633	no	no	no	dn	no	up	HC
CDCA+blood	MCP-1(MCAF)	CDCA+blood-Creatinine+blood+Ethanolamine+blood+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.506	0.0633	no	no	no	dn	no	up	HC
CDCA+blood	MCP-1(MCAF)	CDCA+blood-d18:1-18:1-SM+blood+d18:1-22:1-SM+blood-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.506	0.0633	no	no	no	dn	no	up	HC
CDCA+blood	MCP-1(MCAF)	CDCA+blood-d18:1-18:0-SM+blood+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.506	0.0633	no	no	no	dn	no	up	HC
CDCA+blood	MCP-1(MCAF)	CDCA+blood-d18:1-18:1-SM+blood+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.506	0.0633	no	no	no	dn	no	up	HC
capric acid C6+blood	MCP-1(MCAF)	capric acid C6+blood-Cystine+blood-d18:1-14:0-SM+blood-MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.433	0.0633	no	no	no	dn	no	up	HC
capric acid C6+blood	MCP-1(MCAF)	capric acid C6+blood-Cystine+blood+L-Asparagine+blood+MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.433	0.0633	no	no	no	dn	no	up	HC
capric acid C6+blood	MCP-1(MCAF)	capric acid C6+blood-Cystine+blood-IL-9-MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.433	0.0633	no	no	no	dn	no	up	HC
Prevotella	MCP-1(MCAF)	Prevotella-24:1+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	HC
Prevotella	MCP-1(MCAF)	Prevotella-16:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	HC
Prevotella	MCP-1(MCAF)	Prevotella-L-Tryptophan+stool-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.287	0.0633	no	no	no	dn	no	up	HC
TCA+blood	MCP-1(MCAF)	"TCA+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine+DL-Indole-3-lactic acid+urine-MCP-1(MCAF)"	Indirect	serum_bileacids	serum_cytokines	0.339	0.0633	no	no	no	dn	no	up	HC
iso-DCA+blood	MCP-1(MCAF)	iso-DCA+blood+L-Histidine+blood+L-Methionine+blood-IL-9-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.38	0.0633	no	no	no	dn	no	up	HC
iso-DCA+blood	MCP-1(MCAF)	iso-DCA+blood+L-Histidine+blood+L-Lysine+blood-IL-9-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.38	0.0633	no	no	no	dn	no	up	HC
HCA+stool	MCP-1(MCAF)	HCA+stool+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.155	0.0633	no	no	no	dn	no	up	HC
HCA+stool	MCP-1(MCAF)	HCA+stool-ACA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.155	0.0633	no	no	no	dn	no	up	HC
Roseburia	MCP-1(MCAF)	Roseburia+Malaria+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.495	0.0633	no	no	no	dn	no	up	HC
Roseburia	MCP-1(MCAF)	Roseburia-T cell receptor signaling pathway-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.495	0.0633	no	no	no	dn	no	up	HC
Roseburia	MCP-1(MCAF)	Roseburia-Measles-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.495	0.0633	no	no	no	dn	no	up	HC
Roseburia	MCP-1(MCAF)	Roseburia-NF-kappa B signaling pathway-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.495	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+stool	MCP-1(MCAF)	12-ketoDCA+stool+LCA+stool+16:0/18:2-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.505	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+stool	MCP-1(MCAF)	12-ketoDCA+stool-Cystine+blood-d18:1-14:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.505	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+stool	MCP-1(MCAF)	12-ketoDCA+stool-Cystine+blood-IL-9-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.505	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+stool	MCP-1(MCAF)	12-ketoDCA+stool-Cystine+blood+L-Asparagine+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.505	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+stool	MCP-1(MCAF)	12-ketoDCA+stool-CA+stool-18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.505	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+stool	MCP-1(MCAF)	12-ketoDCA+stool+LCA+stool+18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.505	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+stool	MCP-1(MCAF)	12-ketoDCA+stool-CA+stool-Propionic acid+stool+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.505	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+stool	MCP-1(MCAF)	12-ketoDCA+stool-CA+stool-ACA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.505	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+stool	MCP-1(MCAF)	12-ketoDCA+stool+DCA+stool-L-Tryptophan+stool-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.505	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+stool	MCP-1(MCAF)	12-ketoDCA+stool-CA+stool-HDCA+stool+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.505	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+stool	MCP-1(MCAF)	12-ketoDCA+stool-CDCA+stool-HDCA+stool+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.505	0.0633	no	no	no	dn	no	up	HC
GLCA+blood	MCP-1(MCAF)	GLCA+blood+L-Glutamine+blood-IL-9-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.319	0.0633	no	no	no	dn	no	up	HC
L-Tryptophan+stool	MCP-1(MCAF)	L-Tryptophan+stool-MCP-1(MCAF)	Direct	stool_cometabolism	serum_cytokines	0.557	0.0633	no	no	no	dn	no	up	HC
CA+blood	MCP-1(MCAF)	CA+blood+CDCA+blood-d18:1-18:1-SM+blood+d18:1-22:1-SM+blood-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.606	0.0633	no	no	no	dn	no	up	HC
CA+blood	MCP-1(MCAF)	CA+blood+CDCA+blood-Creatinine+blood+Ethanolamine+blood+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.606	0.0633	no	no	no	dn	no	up	HC
CA+blood	MCP-1(MCAF)	CA+blood-L-Isoleucine+blood+L-Lysine+blood-IL-9-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.606	0.0633	no	no	no	dn	no	up	HC
CA+blood	MCP-1(MCAF)	CA+blood+CDCA+blood-Creatinine+blood+L-Asparagine+blood+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.606	0.0633	no	no	no	dn	no	up	HC
CA+blood	MCP-1(MCAF)	CA+blood+CDCA+blood-d18:1-18:0-SM+blood+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.606	0.0633	no	no	no	dn	no	up	HC
CA+blood	MCP-1(MCAF)	CA+blood+CDCA+blood-d18:1-18:1-SM+blood+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.606	0.0633	no	no	no	dn	no	up	HC
GUDCA+stool	MCP-1(MCAF)	GUDCA+stool+L-Tryptophan+stool-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0085	0.0633	no	dn	no	dn	no	up	HC
L-Phenylalanine+stool	MCP-1(MCAF)	L-Phenylalanine+stool+L-Tryptophan+stool-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0633	no	no	no	dn	no	up	HC
butyric acid C4+blood	MCP-1(MCAF)	butyric acid C4+blood+Cystine+blood-IL-9-MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.407	0.0633	no	no	no	dn	no	up	HC
butyric acid C4+blood	MCP-1(MCAF)	butyric acid C4+blood+heptanoic acid C7+blood+L-Asparagine+blood+MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.407	0.0633	no	no	no	dn	no	up	HC
butyric acid C4+blood	MCP-1(MCAF)	butyric acid C4+blood+Cystine+blood+L-Asparagine+blood+MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.407	0.0633	no	no	no	dn	no	up	HC
butyric acid C4+blood	MCP-1(MCAF)	butyric acid C4+blood+Cystine+blood-d18:1-14:0-SM+blood-MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.407	0.0633	no	no	no	dn	no	up	HC
GCA+stool	MCP-1(MCAF)	GCA+stool-Propionic acid+stool+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0633	no	no	no	dn	no	up	HC
Coprococcus	MCP-1(MCAF)	Coprococcus-Influenza A+L-Tryptophan+stool-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	HC
Coprococcus	MCP-1(MCAF)	Coprococcus+16:0/20:4-PI+blood-16:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	HC
Coprococcus	MCP-1(MCAF)	Coprococcus-Lysosome+24:1+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	HC
Coprococcus	MCP-1(MCAF)	Coprococcus+16:0/20:4-PI+blood-20:3/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	HC
Coprococcus	MCP-1(MCAF)	Coprococcus-18:1/18:2-PG+blood+20:3/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	HC
Coprococcus	MCP-1(MCAF)	Coprococcus+TCA+stool-18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	HC
Coprococcus	MCP-1(MCAF)	Coprococcus+16:0/20:4-PI+blood-18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	HC
Coprococcus	MCP-1(MCAF)	Coprococcus+16:0/20:4-PI+blood+d18:1-14:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	HC
Coprococcus	MCP-1(MCAF)	Coprococcus-18:2-LPC+blood-d18:1-14:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	HC
Coprococcus	MCP-1(MCAF)	Coprococcus+16:0/20:4-PI+blood-Ethanolamine+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	HC
Coprococcus	MCP-1(MCAF)	Coprococcus-Influenza A+Ethanolamine+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	HC
Coprococcus	MCP-1(MCAF)	Coprococcus-Lysosome-Butyric acid+stool+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	HC
Coprococcus	MCP-1(MCAF)	Coprococcus+Lachnospira-Inflammatory bowel disease+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	HC
Coprococcus	MCP-1(MCAF)	Coprococcus+TCA+stool-16:0/18:2-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	HC
Coprococcus	MCP-1(MCAF)	Coprococcus+Ribosome biogenesis in eukaryotes+Propionic acid+stool+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	HC
Coprococcus	MCP-1(MCAF)	Coprococcus+Primary immunodeficiency-L-Asparagine+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	HC
Coprococcus	MCP-1(MCAF)	Coprococcus-Influenza A+L-Asparagine+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.612	0.0633	no	no	no	dn	no	up	HC
Oscillospira	MCP-1(MCAF)	Oscillospira-Human T-cell leukemia virus 1 infection+d18:1-22:1-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	HC
Oscillospira	MCP-1(MCAF)	Oscillospira-Antigen processing and presentation+d18:1-22:1-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	HC
Oscillospira	MCP-1(MCAF)	Oscillospira-Human T-cell leukemia virus 1 infection+d18:1-22:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	HC
Oscillospira	MCP-1(MCAF)	Oscillospira-Salmonella infection+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	HC
Oscillospira	MCP-1(MCAF)	Oscillospira-nutriCA+stool+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	HC
Oscillospira	MCP-1(MCAF)	Oscillospira-HCA+stool+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	HC
Oscillospira	MCP-1(MCAF)	Oscillospira-Human T-cell leukemia virus 1 infection+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	HC
Oscillospira	MCP-1(MCAF)	Oscillospira-Antigen processing and presentation+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	HC
Oscillospira	MCP-1(MCAF)	Oscillospira-9-HODE+blood-Ethanolamine+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	HC
Oscillospira	MCP-1(MCAF)	Oscillospira+DCA+stool-L-Tryptophan+stool-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	HC
Oscillospira	MCP-1(MCAF)	Oscillospira-9-HODE+blood-L-Asparagine+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	HC
Oscillospira	MCP-1(MCAF)	Oscillospira-nutriCA+stool-ACA+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	HC
Oscillospira	MCP-1(MCAF)	Oscillospira-HCA+stool-ACA+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	HC
Oscillospira	MCP-1(MCAF)	Oscillospira-4-hydroxybenzoic acid+stool+Acetic acid+stool+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	HC
Oscillospira	MCP-1(MCAF)	Oscillospira+LCA+stool+18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	HC
Oscillospira	MCP-1(MCAF)	Oscillospira+LCA+stool+16:0/18:2-PC+blood+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.62	0.0633	no	no	no	dn	no	up	HC
HCA+blood	MCP-1(MCAF)	HCA+blood-L-2-Aminobutyric acid+blood+L-Lysine+blood-IL-9-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.544	0.0633	no	no	no	dn	no	up	HC
HCA+blood	MCP-1(MCAF)	HCA+blood-L-Isoleucine+blood+L-Lysine+blood-IL-9-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.544	0.0633	no	no	no	dn	no	up	HC
HCA+blood	MCP-1(MCAF)	HCA+blood-L-2-Aminobutyric acid+blood+L-Methionine+blood-IL-9-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.544	0.0633	no	no	no	dn	no	up	HC
iso-LCA+stool	MCP-1(MCAF)	iso-LCA+stool-nutriCA+stool-ACA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.72	0.0633	no	no	no	dn	no	up	HC
iso-LCA+stool	MCP-1(MCAF)	iso-LCA+stool-16:0/18:3-PC+blood+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.72	0.0633	no	no	no	dn	no	up	HC
iso-LCA+stool	MCP-1(MCAF)	iso-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.72	0.0633	no	no	no	dn	no	up	HC
iso-LCA+stool	MCP-1(MCAF)	iso-LCA+stool+LCA+stool+16:0/18:2-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.72	0.0633	no	no	no	dn	no	up	HC
iso-LCA+stool	MCP-1(MCAF)	iso-LCA+stool+LCA+stool+18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.72	0.0633	no	no	no	dn	no	up	HC
2-methyl-butyric acid m-C4+blood	MCP-1(MCAF)	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+L-Asparagine+blood+MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.262	0.0633	no	no	no	dn	no	up	HC
2-methyl-butyric acid m-C4+blood	MCP-1(MCAF)	2-methyl-butyric acid m-C4+blood+20:1+blood+d18:1-22:1-SM+blood-MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.262	0.0633	no	no	no	dn	no	up	HC
2-methyl-butyric acid m-C4+blood	MCP-1(MCAF)	2-methyl-butyric acid m-C4+blood+20:1+blood+DL-Indole-3-lactic acid+urine-MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.262	0.0633	no	no	no	dn	no	up	HC
DCA+blood	MCP-1(MCAF)	"DCA+blood-n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine+DL-Indole-3-lactic acid+urine-MCP-1(MCAF)"	Indirect	serum_bileacids	serum_cytokines	0.122	0.0633	no	no	no	dn	no	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool-L-Ornithine+blood-IL-9-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool+14:0/18:2-PC+blood-L-Asparagine+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/20:3-PC+blood-L-Asparagine+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	MCP-1(MCAF)	3-(3-Hydroxyphenyl)propanoic acid+stool+20:2/18:0-PC+blood-L-Asparagine+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0633	no	no	no	dn	no	up	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	MCP-1(MCAF)	"3-(3,4-dihydroxyphenyl)propionic acid+urine+DL-Indole-3-lactic acid+urine-MCP-1(MCAF)"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.0633	up	up	no	dn	no	up	HC
GLCA+stool	MCP-1(MCAF)	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.617	0.0633	no	no	no	dn	no	up	HC
GLCA+stool	MCP-1(MCAF)	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.617	0.0633	no	no	no	dn	no	up	HC
Indole-3-Acetic acid+stool	MCP-1(MCAF)	Indole-3-Acetic acid+stool+L-Tryptophan+stool-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0633	no	no	no	dn	no	up	HC
TCA+stool	MCP-1(MCAF)	TCA+stool-16:0/18:2-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.458	0.0633	no	no	no	dn	no	up	HC
TCA+stool	MCP-1(MCAF)	TCA+stool-18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.458	0.0633	no	no	no	dn	no	up	HC
HDCA+stool	MCP-1(MCAF)	HDCA+stool+MCP-1(MCAF)	Direct	stool_bileacids	serum_cytokines	0.176	0.0633	no	no	no	dn	no	up	HC
Lachnospira	MCP-1(MCAF)	Lachnospira-Inflammatory bowel disease+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.279	0.0633	no	no	no	dn	no	up	HC
isobutyric acid C4+blood	MCP-1(MCAF)	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood-IL-9-MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.0151	0.0633	up	up	no	dn	no	up	HC
GCDCA+stool	MCP-1(MCAF)	GCDCA+stool-Propionic acid+stool+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0633	no	dn	no	dn	no	up	HC
5-Hydroxytryptamine+stool	MCP-1(MCAF)	5-Hydroxytryptamine+stool-Propionic acid+stool+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0633	dn	dn	no	dn	no	up	HC
Odoribacter	MCP-1(MCAF)	Odoribacter+Inflammatory bowel disease+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.798	0.0633	no	no	no	dn	no	up	HC
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+Phenylacetic acid+stool+20:1+blood+d18:1-22:1-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	HC
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+Phenylacetic acid+stool+d18:1-20:1-SM+blood+d18:1-22:1-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	HC
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/20:4-PI+blood-16:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	HC
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+Isovaleric acid+stool-nutriCA+stool-ACA+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	HC
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+Isovaleric acid+stool-nutriCA+stool+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	HC
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/20:4-PI+blood-18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	HC
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	HC
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/20:4-PI+blood+d18:1-14:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	HC
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/20:4-PI+blood-20:3/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	HC
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-20:3/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	HC
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Asparagine+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	HC
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/20:4-PI+blood-Ethanolamine+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	HC
Isobutyric acid+stool	MCP-1(MCAF)	Isobutyric acid+stool+Phenylacetic acid+stool+20:1+blood+DL-Indole-3-lactic acid+urine-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.408	0.0633	no	no	no	dn	no	up	HC
2-hydroxyphenylacetic acid+urine	MCP-1(MCAF)	2-hydroxyphenylacetic acid+urine-DL-Indole-3-lactic acid+urine-MCP-1(MCAF)	Indirect	urine_cometabolism	serum_cytokines	0.763	0.0633	no	no	no	dn	no	up	HC
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-nutriCA+stool+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	HC
Kynurenic acid+stool	MCP-1(MCAF)	Kynurenic acid+stool-nutriCA+stool-ACA+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0633	dn	dn	no	dn	no	up	HC
Eggerthella	MCP-1(MCAF)	Eggerthella+Clostridium-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.912	0.0633	no	no	no	dn	no	up	HC
Anaerotruncus	MCP-1(MCAF)	Anaerotruncus-Gemmiger-L-Tryptophan+stool-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.904	0.0633	no	no	no	dn	no	up	HC
Anaerostipes	MCP-1(MCAF)	Anaerostipes-Inflammatory bowel disease+MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.568	0.0633	no	no	no	dn	no	up	HC
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-nutriCA+stool+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	HC
Isovaleric acid+stool	MCP-1(MCAF)	Isovaleric acid+stool-nutriCA+stool-ACA+blood+MCP-1(MCAF)	Indirect	stool_scfa	serum_cytokines	0.343	0.0633	no	no	no	dn	no	up	HC
Paraprevotella	MCP-1(MCAF)	Paraprevotella+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.118	0.0633	no	no	no	dn	no	up	HC
DL-Indole-3-lactic acid+urine	MCP-1(MCAF)	DL-Indole-3-lactic acid+urine-MCP-1(MCAF)	Direct	urine_cometabolism	serum_cytokines	0.00552	0.0633	up	up	no	dn	no	up	HC
iso-LCA+blood	MCP-1(MCAF)	"iso-LCA+blood+L-Proline+blood-MUFA+blood+n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine+DL-Indole-3-lactic acid+urine-MCP-1(MCAF)"	Indirect	serum_bileacids	serum_cytokines	0.507	0.0633	no	no	no	dn	no	up	HC
¦Ø-MCA+stool	MCP-1(MCAF)	¦Ø-MCA+stool-Propionic acid+stool+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.919	0.0633	no	no	no	dn	no	up	HC
¦Ø-MCA+stool	MCP-1(MCAF)	¦Ø-MCA+stool-Acetic acid+stool+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.919	0.0633	no	no	no	dn	no	up	HC
¦Ø-MCA+stool	MCP-1(MCAF)	¦Ø-MCA+stool-Butyric acid+stool+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.919	0.0633	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	MCP-1(MCAF)	Phenylacetic acid+stool-16:0/20:4-PI+blood-18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0633	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	MCP-1(MCAF)	Phenylacetic acid+stool-16:0/18:2-PI+blood-18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0633	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	MCP-1(MCAF)	Phenylacetic acid+stool-16:0/20:4-PI+blood-16:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0633	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	MCP-1(MCAF)	Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Asparagine+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0633	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	MCP-1(MCAF)	Phenylacetic acid+stool-16:0/20:4-PI+blood-Ethanolamine+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0633	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	MCP-1(MCAF)	Phenylacetic acid+stool+20:1+blood+d18:1-22:1-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0633	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	MCP-1(MCAF)	Phenylacetic acid+stool+d18:1-20:1-SM+blood+d18:1-22:1-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0633	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	MCP-1(MCAF)	Phenylacetic acid+stool-16:0/20:4-PI+blood-20:3/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0633	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	MCP-1(MCAF)	Phenylacetic acid+stool-16:0/18:2-PI+blood-20:3/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0633	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	MCP-1(MCAF)	Phenylacetic acid+stool-16:0/20:4-PI+blood+d18:1-14:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0633	no	no	no	dn	no	up	HC
Phenylacetic acid+stool	MCP-1(MCAF)	Phenylacetic acid+stool+20:1+blood+DL-Indole-3-lactic acid+urine-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0633	no	no	no	dn	no	up	HC
Gemmiger	MCP-1(MCAF)	Gemmiger-L-Tryptophan+stool-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.595	0.0633	no	no	no	dn	no	up	HC
GDCA+stool	MCP-1(MCAF)	GDCA+stool+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.656	0.0633	no	no	no	dn	no	up	HC
GDCA+stool	MCP-1(MCAF)	GDCA+stool-18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.656	0.0633	no	no	no	dn	no	up	HC
GDCA+stool	MCP-1(MCAF)	GDCA+stool+d18:1-22:1-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.656	0.0633	no	no	no	dn	no	up	HC
GDCA+stool	MCP-1(MCAF)	GDCA+stool-16:0/18:2-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.656	0.0633	no	no	no	dn	no	up	HC
GDCA+stool	MCP-1(MCAF)	GDCA+stool-Propionic acid+stool+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.656	0.0633	no	no	no	dn	no	up	HC
GDCA+stool	MCP-1(MCAF)	GDCA+stool+d18:1-16:1-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.656	0.0633	no	no	no	dn	no	up	HC
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+18:1/18:1-PE+blood-20:3/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	HC
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+18:1/18:1-PE+blood-ACA+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	HC
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+16:0/22:6-PE+blood-ACA+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	HC
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+18:1/18:1-PE+blood-24:1+blood+MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	HC
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+18:1/18:1-PE+blood+IL-9-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	HC
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+8-HETE+blood+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	HC
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+16:0/22:6-PE+blood+d18:1-16:1-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	HC
L-Tyrosine+stool	MCP-1(MCAF)	L-Tyrosine+stool+16:0/22:6-PE+blood+d18:1-14:0-SM+blood-MCP-1(MCAF)	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0633	no	no	no	dn	no	up	HC
CDCA+stool	MCP-1(MCAF)	CDCA+stool-HDCA+stool+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.663	0.0633	no	no	no	dn	no	up	HC
CA+stool	MCP-1(MCAF)	CA+stool-ACA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	HC
CA+stool	MCP-1(MCAF)	CA+stool-Propionic acid+stool+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	HC
CA+stool	MCP-1(MCAF)	CA+stool-HDCA+stool+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	HC
CA+stool	MCP-1(MCAF)	CA+stool-18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.827	0.0633	no	no	no	dn	no	up	HC
HDCA+blood	MCP-1(MCAF)	HDCA+blood+L-Asparagine+blood+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.483	0.0633	no	no	no	dn	no	up	HC
TLCA+stool	MCP-1(MCAF)	TLCA+stool+IL-9-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.243	0.0633	no	no	no	dn	no	up	HC
UDCA+stool	MCP-1(MCAF)	UDCA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.266	0.0633	no	no	no	dn	no	up	HC
nutriCA+stool	MCP-1(MCAF)	nutriCA+stool+d18:1-20:0-SM+blood-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.481	0.0633	no	no	no	dn	no	up	HC
nutriCA+stool	MCP-1(MCAF)	nutriCA+stool-ACA+blood+MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.481	0.0633	no	no	no	dn	no	up	HC
acetic acid C2+blood	MCP-1(MCAF)	acetic acid C2+blood+heptanoic acid C7+blood+L-Asparagine+blood+MCP-1(MCAF)	Indirect	serum_scfa	serum_cytokines	0.000193	0.0633	up	dn	no	dn	no	up	HC
Clostridium	MCP-1(MCAF)	Clostridium-MCP-1(MCAF)	Direct	Genus	serum_cytokines	0.925	0.0633	no	no	no	dn	no	up	HC
T-¦Á-MCA+stool	MCP-1(MCAF)	T-¦Á-MCA+stool-TLCA+stool+IL-9-MCP-1(MCAF)	Indirect	stool_bileacids	serum_cytokines	0.48	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+blood	MCP-1(MCAF)	12-ketoDCA+blood+16:0/16:1-PI+blood-Ethanolamine+blood+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.517	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+blood	MCP-1(MCAF)	12-ketoDCA+blood+14:0/16:0-PC+blood-L-Asparagine+blood+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.517	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+blood	MCP-1(MCAF)	12-ketoDCA+blood+16:0/16:1-PI+blood-16:0/18:2-PC+blood+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.517	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+blood	MCP-1(MCAF)	12-ketoDCA+blood+16:0/16:1-PI+blood-16:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.517	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+blood	MCP-1(MCAF)	12-ketoDCA+blood+16:0/16:1-PI+blood-20:3/16:0-PC+blood+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.517	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+blood	MCP-1(MCAF)	12-ketoDCA+blood-18:2/16:0-PC+blood+20:3/16:0-PC+blood+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.517	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+blood	MCP-1(MCAF)	12-ketoDCA+blood-18:2n6c+blood-DL-Indole-3-lactic acid+urine-MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.517	0.0633	no	no	no	dn	no	up	HC
12-ketoDCA+blood	MCP-1(MCAF)	12-ketoDCA+blood+16:0/16:1-PI+blood-18:1/16:0-PC+blood+MCP-1(MCAF)	Indirect	serum_bileacids	serum_cytokines	0.517	0.0633	no	no	no	dn	no	up	HC
Butyricicoccus	MCP-1(MCAF)	Butyricicoccus-MCP-1(MCAF)	Direct	Genus	serum_cytokines	0.852	0.0633	no	no	no	dn	no	up	HC
Wautersiella	MCP-1(MCAF)	Wautersiella+Butyricicoccus-MCP-1(MCAF)	Indirect	Genus	serum_cytokines	0.289	0.0633	no	no	no	dn	no	up	HC
Blautia	RANTES	Blautia+Peroxisome-Prion disease-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia+Peroxisome-Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia+Peroxisome-Thermogenesis-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia+Arginine and proline metabolism-Thermogenesis-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia+Peroxisome-Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia-Cushing syndrome+Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia+Arginine and proline metabolism-Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia+Peroxisome-Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia-Cushing syndrome+Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia-Ras signaling pathway+Neurotrophin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia+Peroxisome-Cardiac muscle contraction-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia+16:0/20:5-PC+blood+22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia-Butyric acid+stool+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia-Ras signaling pathway+Signaling pathways regulating pluripotency of stem cells-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia+Peroxisome-Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia-Chemical carcinogenesis - receptor activation+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia-Cushing syndrome+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia-18:1-LPE+blood-TXB2+blood+RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia+Peroxisome-Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	"Blautia+Peroxisome-Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia+Peroxisome-Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia-Cushing syndrome+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia+Arginine and proline metabolism-Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia+Peroxisome-Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia-Cushing syndrome+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Blautia	RANTES	Blautia+Arginine and proline metabolism-Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	1.36E-05	0.0757	up	dn	dn	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-TNF signaling pathway-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-TNF signaling pathway-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-mRNA surveillance pathway+TNF signaling pathway-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Phosphatidylinositol signaling system+Cardiac muscle contraction-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Biosynthesis of amino acids-Cardiac muscle contraction-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-RNA degradation+Cardiac muscle contraction-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-Cardiac muscle contraction-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-Cardiac muscle contraction-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-mRNA surveillance pathway+Cardiac muscle contraction-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Phosphatidylinositol signaling system+Neurotrophin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Biosynthesis of amino acids-Neurotrophin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-RNA degradation+Neurotrophin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-Neurotrophin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-Neurotrophin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-mRNA surveillance pathway+Neurotrophin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-Oxidative phosphorylation-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Phosphatidylinositol signaling system+Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Biosynthesis of amino acids-Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-RNA degradation+Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-mRNA surveillance pathway+Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Phosphatidylinositol signaling system+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Biosynthesis of amino acids-Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-RNA degradation+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-mRNA surveillance pathway+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Pathways in cancer-IP-10+RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+16:0/18:1-PC+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Phosphatidylinositol signaling system+Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Biosynthesis of amino acids-Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-RNA degradation+Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-mRNA surveillance pathway+Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Phosphatidylinositol signaling system+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Biosynthesis of amino acids-Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-RNA degradation+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-mRNA surveillance pathway+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Phosphatidylinositol signaling system+Prion disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Biosynthesis of amino acids-Prion disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-RNA degradation+Prion disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-Prion disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-Prion disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-mRNA surveillance pathway+Prion disease-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Phosphatidylinositol signaling system+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Biosynthesis of amino acids-Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-RNA degradation+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Colorectal cancer+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Pathways in cancer+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-mRNA surveillance pathway+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+16:0/18:1-PC+blood+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+16:1/18:2-PG+blood+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Phosphatidylinositol signaling system+Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Biosynthesis of amino acids-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-RNA degradation+Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Colorectal cancer+Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Pathways in cancer+Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-mRNA surveillance pathway+Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Phosphatidylinositol signaling system+Signaling pathways regulating pluripotency of stem cells-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Biosynthesis of amino acids-Signaling pathways regulating pluripotency of stem cells-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-RNA degradation+Signaling pathways regulating pluripotency of stem cells-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-Signaling pathways regulating pluripotency of stem cells-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-Signaling pathways regulating pluripotency of stem cells-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-mRNA surveillance pathway+Signaling pathways regulating pluripotency of stem cells-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Phosphatidylinositol signaling system+Thermogenesis-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Biosynthesis of amino acids-Thermogenesis-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-RNA degradation+Thermogenesis-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-Thermogenesis-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-Thermogenesis-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-mRNA surveillance pathway+Thermogenesis-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Phosphatidylinositol signaling system+Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Biosynthesis of amino acids-Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-RNA degradation+Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-mRNA surveillance pathway+Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	"Parabacteroides+Biosynthesis of amino acids-Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	"Parabacteroides-RNA degradation+Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	"Parabacteroides+Carbon metabolism-Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	"Parabacteroides+Glycolysis / Gluconeogenesis-Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	"Parabacteroides-mRNA surveillance pathway+Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Biosynthesis of amino acids-Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-RNA degradation+Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-mRNA surveillance pathway+Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-RNA degradation+Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Colorectal cancer+Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Pathways in cancer+Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-mRNA surveillance pathway+Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Colorectal cancer+PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Pathways in cancer+PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-mRNA surveillance pathway+PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-Phosphatidylinositol signaling system+Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Biosynthesis of amino acids-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-RNA degradation+Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides-mRNA surveillance pathway+Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Carbon metabolism-Hepatitis C-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Parabacteroides	RANTES	Parabacteroides+Glycolysis / Gluconeogenesis-Hepatitis C-RANTES	Indirect	Genus	serum_cytokines	4.19E-05	0.0757	no	up	up	no	no	up	HC
Dorea	RANTES	Dorea-VEGF signaling pathway+Signaling pathways regulating pluripotency of stem cells-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-Endocrine resistance+Signaling pathways regulating pluripotency of stem cells-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-VEGF signaling pathway+TNF signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-VEGF signaling pathway+Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-Fc epsilon RI signaling pathway+Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-VEGF signaling pathway+C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-Endocrine resistance+Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-GnRH signaling pathway+Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	"Dorea-Endocrine resistance+Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	"Dorea-GnRH signaling pathway+Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-Endocrine resistance+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-GnRH signaling pathway+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-VEGF signaling pathway+Hepatitis C-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-Fc epsilon RI signaling pathway+Hepatitis C-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-Endocrine resistance+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-VEGF signaling pathway+Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-Thyroid hormone signaling pathway-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-Fc epsilon RI signaling pathway+Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-Endocrine resistance+Thermogenesis-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-16:0-LPC+blood+TXB2+blood+RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-VEGF signaling pathway+Neurotrophin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-Fc epsilon RI signaling pathway+Neurotrophin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea+Legionellosis-Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-Amphetamine addiction+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-Chemical carcinogenesis - receptor activation+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-Endocrine resistance+Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-GnRH signaling pathway+Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-VEGF signaling pathway+PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-Fc epsilon RI signaling pathway+PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	"Dorea-Growth hormone synthesis, secretion and action+PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES"	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-VEGF signaling pathway+Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-Fc epsilon RI signaling pathway+Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	"Dorea-Growth hormone synthesis, secretion and action+Prostate cancer-RANTES"	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-VEGF signaling pathway+Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-Endocrine resistance+Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-GnRH signaling pathway+Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Dorea	RANTES	Dorea-Endocrine resistance+Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	0.00362	0.0757	up	no	dn	no	no	up	HC
Faecalibacterium	RANTES	Faecalibacterium-RANTES	Direct	Genus	serum_cytokines	0.0039	0.0757	no	dn	dn	no	no	up	HC
TUDCA+blood	RANTES	TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.0282	0.0757	no	no	dn	no	no	up	HC
TUDCA+blood	RANTES	TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.0282	0.0757	no	no	dn	no	no	up	HC
isocapric acid iso-C6+blood	RANTES	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+Serine+blood+L-Tyrosine+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.0458	0.0757	no	no	dn	no	no	up	HC
isocapric acid iso-C6+blood	RANTES	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+Serine+blood+L-Tyrosine+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.0458	0.0757	no	no	dn	no	no	up	HC
isocapric acid iso-C6+blood	RANTES	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+Serine+blood+L-Tyrosine+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.0458	0.0757	no	no	dn	no	no	up	HC
isocapric acid iso-C6+blood	RANTES	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+UFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.0458	0.0757	no	no	dn	no	no	up	HC
isocapric acid iso-C6+blood	RANTES	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.0458	0.0757	no	no	dn	no	no	up	HC
isocapric acid iso-C6+blood	RANTES	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+L-Histidine+blood+L-Tyrosine+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.0458	0.0757	no	no	dn	no	no	up	HC
isocapric acid iso-C6+blood	RANTES	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.0458	0.0757	no	no	dn	no	no	up	HC
isocapric acid iso-C6+blood	RANTES	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.0458	0.0757	no	no	dn	no	no	up	HC
Bacteroides	RANTES	Bacteroides+RANTES	Direct	Genus	serum_cytokines	0.000267	0.0757	dn	dn	up	no	no	up	HC
Propionic acid+stool	RANTES	Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine-RANTES	Indirect	stool_scfa	serum_cytokines	0.0436	0.0757	dn	no	up	no	no	up	HC
Propionic acid+stool	RANTES	Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine-RANTES	Indirect	stool_scfa	serum_cytokines	0.0436	0.0757	dn	no	up	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Ovarian steroidogenesis+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Protein export+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Apelin signaling pathway+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Cushing syndrome+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Ovarian steroidogenesis+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Protein export+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Apelin signaling pathway+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Cushing syndrome+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Protein export+Prion disease-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	"[Ruminococcus]+Proteasome+Insulin signaling pathway+Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	"[Ruminococcus]+Proteasome+Protein export+Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	"[Ruminococcus]+Proteasome+Apelin signaling pathway+Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Spinocerebellar ataxia+PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Hippo signaling pathway-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Hepatocellular carcinoma-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Oxytocin signaling pathway-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Renal cell carcinoma+PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Platelet activation-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Vibrio cholerae infection-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Autophagy - other+PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Adherens junction-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Focal adhesion-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Gastric acid secretion-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Spinocerebellar ataxia+Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Hippo signaling pathway-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Oxytocin signaling pathway-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Renal cell carcinoma+Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Platelet activation-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Vibrio cholerae infection-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Autophagy - other+Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Adherens junction-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Focal adhesion-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Gastric acid secretion-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Renal cell carcinoma+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Protein export+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Cushing syndrome+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-HDCA+stool+16:0/20:4-PC+blood-22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-18:0/20:4-PI+blood+18:1-LPC+blood-22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-18:0/20:4-PI+blood-20:5n3+blood+22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-HDCA+stool+20:3/16:0-PC+blood-22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Protein export+Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Cushing syndrome+Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Protein export+Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Cushing syndrome+Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Protein export+Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Spinocerebellar ataxia+Hepatitis C-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Autophagy - other+Hepatitis C-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Protein export+Cardiac muscle contraction-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Autophagy - other+T cell receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Spinocerebellar ataxia+Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Oxytocin signaling pathway-Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Renal cell carcinoma+Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Platelet activation-Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Vibrio cholerae infection-Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Autophagy - other+Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Focal adhesion-Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Gastric acid secretion-Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+HIF-1 signaling pathway+PI3K-Akt signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Rap1 signaling pathway-PI3K-Akt signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Autophagy - other+PI3K-Akt signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Hippo signaling pathway-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Oxytocin signaling pathway-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Platelet activation-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Rap1 signaling pathway-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Protein export+Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Thyroid hormone signaling pathway-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Autophagy - other+Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Adherens junction-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Focal adhesion-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Hippo signaling pathway-C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Platelet activation-C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Autophagy - other+C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Adherens junction-C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Focal adhesion-C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+nutriCA+stool-L-Homocystine+blood-TXB2+blood+RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+nutriCA+stool-L-Homocystine+blood-IP-10+RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-18:0/20:4-PI+blood+18:1/20:4-PC+blood-IP-10+RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-HDCA+stool+16:0/18:1-PC+blood+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-HDCA+stool+18:0/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-HDCA+stool+16:0/20:4-PC+blood+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-18:0/20:4-PI+blood+18:1/20:4-PC+blood+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+16:0/18:3-PC+blood-2-hydroxyhippuric acid+urine-L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-HDCA+stool+20:3/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-HDCA+stool-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+nutriCA+stool+TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-HDCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-HDCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-HDCA+stool+16:0/20:4-PC+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-18:0/20:4-PI+blood+18:1-LPC+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-18:0/20:4-PI+blood+18:1/20:4-PC+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+16:0/18:3-PC+blood-2-hydroxyhippuric acid+urine-L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-HDCA+stool+20:3/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]-HDCA+stool-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+nutriCA+stool+TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Hippo signaling pathway-TNF signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Platelet activation-TNF signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Autophagy - other+TNF signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Adherens junction-TNF signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome-Focal adhesion-TNF signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Protein export+Thermogenesis-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Autophagy - other+Neurotrophin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Protein export+Signaling pathways regulating pluripotency of stem cells-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Autophagy - other+Signaling pathways regulating pluripotency of stem cells-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
[Ruminococcus]	RANTES	[Ruminococcus]+Proteasome+Autophagy - other+Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0679	0.0757	no	no	dn	no	no	up	HC
GUDCA+blood	RANTES	GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0757	no	no	dn	no	no	up	HC
GUDCA+blood	RANTES	GUDCA+blood-PUFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0757	no	no	dn	no	no	up	HC
GUDCA+blood	RANTES	GUDCA+blood-UFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0757	no	no	dn	no	no	up	HC
GUDCA+blood	RANTES	GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0757	no	no	dn	no	no	up	HC
GUDCA+blood	RANTES	GUDCA+blood+TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0757	no	no	dn	no	no	up	HC
GUDCA+blood	RANTES	GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0757	no	no	dn	no	no	up	HC
GUDCA+blood	RANTES	GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0757	no	no	dn	no	no	up	HC
GUDCA+blood	RANTES	GUDCA+blood-PUFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0757	no	no	dn	no	no	up	HC
GUDCA+blood	RANTES	GUDCA+blood-UFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0757	no	no	dn	no	no	up	HC
GUDCA+blood	RANTES	GUDCA+blood-L-Phenylalanine+urine+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0757	no	no	dn	no	no	up	HC
GUDCA+blood	RANTES	GUDCA+blood+TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0757	no	no	dn	no	no	up	HC
GUDCA+blood	RANTES	GUDCA+blood-iso-DCA+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0757	no	no	dn	no	no	up	HC
Acetic acid+stool	RANTES	Acetic acid+stool+Butyric acid+stool+L-Tyrosine+urine-RANTES	Indirect	stool_scfa	serum_cytokines	0.0656	0.0757	dn	no	no	no	no	up	HC
Acetic acid+stool	RANTES	Acetic acid+stool-18:2/20:4-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_scfa	serum_cytokines	0.0656	0.0757	dn	no	no	no	no	up	HC
Acetic acid+stool	RANTES	Acetic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine-RANTES	Indirect	stool_scfa	serum_cytokines	0.0656	0.0757	dn	no	no	no	no	up	HC
Acetic acid+stool	RANTES	Acetic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine-RANTES	Indirect	stool_scfa	serum_cytokines	0.0656	0.0757	dn	no	no	no	no	up	HC
Acetic acid+stool	RANTES	Acetic acid+stool-Phenylacetic acid+stool-22:6n3+blood+RANTES	Indirect	stool_scfa	serum_cytokines	0.0656	0.0757	dn	no	no	no	no	up	HC
Acetic acid+stool	RANTES	Acetic acid+stool-L-Homocystine+blood-IP-10+RANTES	Indirect	stool_scfa	serum_cytokines	0.0656	0.0757	dn	no	no	no	no	up	HC
Acetic acid+stool	RANTES	Acetic acid+stool-L-Homocystine+blood-TXB2+blood+RANTES	Indirect	stool_scfa	serum_cytokines	0.0656	0.0757	dn	no	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Progesterone-mediated oocyte maturation+Hepatitis C-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Autophagy - animal+Hepatitis C-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Cholinergic synapse+Hepatitis C-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-cGMP-PKG signaling pathway+Hepatitis C-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes+SFA%+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes+16:0/18:1-PC+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes+20:3/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes+16:0/20:4-PC+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-16:0/18:2-PI+blood-L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Homovanillic acid+urine-L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes+16:0/18:2-PC+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes+18:1/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes+18:0/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes+SFA%+blood+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes+16:0/18:1-PC+blood+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes+20:3/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes+16:0/20:4-PC+blood+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes+16:0/18:2-PC+blood+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes+18:1/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes+18:0/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-GDCA+stool-TXB2+blood+RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Peroxisome-Cardiac muscle contraction-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Peroxisome-Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Peroxisome-Prion disease-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	"Alistipes-Peroxisome-Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	"Alistipes-NOD-like receptor signaling pathway-Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Transcriptional misregulation in cancer+Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Autophagy - animal+Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Hepatitis B+Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Peroxisome-Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Peroxisome-Thermogenesis-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-NOD-like receptor signaling pathway-Thermogenesis-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Peroxisome-Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Cholinergic synapse+Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Progesterone-mediated oocyte maturation-IP-10+RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Progesterone-mediated oocyte maturation+Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Autophagy - animal+Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Cholinergic synapse+Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Autophagy - animal+C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-NOD-like receptor signaling pathway+C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-cGMP-PKG signaling pathway+C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Autophagy - animal+Neurotrophin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Autophagy - animal+PI3K-Akt signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-FoxO signaling pathway+PI3K-Akt signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-MAPK signaling pathway+PI3K-Akt signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-GABAergic synapse-Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-FoxO signaling pathway-Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Peroxisome-Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-NOD-like receptor signaling pathway-Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Olfactory transduction-Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Primary immunodeficiency-Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Peroxisome-Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Transcriptional misregulation in cancer+Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Progesterone-mediated oocyte maturation+Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Autophagy - animal+Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Hepatitis B+Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Cholinergic synapse+Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-cGMP-PKG signaling pathway+Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Transcriptional misregulation in cancer+PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Progesterone-mediated oocyte maturation+PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Autophagy - animal+PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Hepatitis B+PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Cholinergic synapse+PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-cGMP-PKG signaling pathway+PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Autophagy - animal+TNF signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Autophagy - animal+T cell receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-FoxO signaling pathway+T cell receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-MAPK signaling pathway+T cell receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Autophagy - animal+Signaling pathways regulating pluripotency of stem cells-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes+20:3/16:0-PC+blood-22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-GABAergic synapse+22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes+16:0/20:4-PC+blood-22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes+Phenylacetic acid+stool-22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-GABAergic synapse-Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Peroxisome-Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-NOD-like receptor signaling pathway-Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-GABAergic synapse-Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-Peroxisome-Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Alistipes	RANTES	Alistipes-NOD-like receptor signaling pathway-Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.0114	0.0757	no	up	no	no	no	up	HC
Butyricimonas	RANTES	Butyricimonas+Prion disease-RANTES	Indirect	Genus	serum_cytokines	0.17	0.0757	no	no	no	no	no	up	HC
Butyricimonas	RANTES	Butyricimonas+Neurotrophin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.17	0.0757	no	no	no	no	no	up	HC
Butyricimonas	RANTES	Butyricimonas+PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.17	0.0757	no	no	no	no	no	up	HC
Butyricimonas	RANTES	Butyricimonas+Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	0.17	0.0757	no	no	no	no	no	up	HC
Butyricimonas	RANTES	Butyricimonas+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.17	0.0757	no	no	no	no	no	up	HC
Butyricimonas	RANTES	"Butyricimonas+Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	0.17	0.0757	no	no	no	no	no	up	HC
Collinsella	RANTES	Collinsella-L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	HC
Collinsella	RANTES	Collinsella+IP-10+RANTES	Indirect	Genus	serum_cytokines	0.128	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool-nutriCA+stool-L-Homocystine+blood-TXB2+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool-L-Tryptophan+stool+Phenylacetic acid+stool-22:6n3+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool+LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool+iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool-nutriCA+stool+TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool+iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool+LCA+stool-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool+LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool+LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool+LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool-L-Tryptophan+stool+16:0/22:6-PE+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool-L-Tryptophan+stool+18:1/18:1-PE+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool+LCA+stool+16:0/18:2-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool-nutriCA+stool+TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool+iso-LCA+stool-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool+LCA+stool-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool+LCA+stool+16:0/18:1-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool+LCA+stool+18:1/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool+LCA+stool+18:0/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool-L-Tryptophan+stool+16:0/22:6-PE+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool-L-Tryptophan+stool+18:1/18:1-PE+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
iso-DCA+stool	RANTES	iso-DCA+stool-nutriCA+stool-L-Homocystine+blood-IP-10+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
LCA+stool	RANTES	LCA+stool+16:0/18:2-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.314	0.0757	no	no	no	no	no	up	HC
LCA+stool	RANTES	LCA+stool+16:0/18:1-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.314	0.0757	no	no	no	no	no	up	HC
LCA+stool	RANTES	LCA+stool+18:1/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.314	0.0757	no	no	no	no	no	up	HC
LCA+stool	RANTES	LCA+stool+18:0/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.314	0.0757	no	no	no	no	no	up	HC
LCA+stool	RANTES	LCA+stool-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.314	0.0757	no	no	no	no	no	up	HC
LCA+stool	RANTES	LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.314	0.0757	no	no	no	no	no	up	HC
LCA+stool	RANTES	LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.314	0.0757	no	no	no	no	no	up	HC
LCA+stool	RANTES	LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.314	0.0757	no	no	no	no	no	up	HC
LCA+stool	RANTES	LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.314	0.0757	no	no	no	no	no	up	HC
LCA+stool	RANTES	LCA+stool-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.314	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Ribosome+Cardiac muscle contraction-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Wnt signaling pathway+Prion disease-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Ribosome+Prion disease-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Ribosome+Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Wnt signaling pathway+Thermogenesis-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Ribosome+Thermogenesis-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Wnt signaling pathway+Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Ribosome+Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Wnt signaling pathway+Signaling pathways regulating pluripotency of stem cells-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Ribosome+Signaling pathways regulating pluripotency of stem cells-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Wnt signaling pathway+Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Ribosome+Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Ribosome+Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Wnt signaling pathway+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Ribosome+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Wnt signaling pathway+Neurotrophin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Ribosome+Neurotrophin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Wnt signaling pathway+Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Ribosome+Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	"Akkermansia-Wnt signaling pathway+Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	"Akkermansia-Ribosome+Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Wnt signaling pathway+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Ribosome+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Wnt signaling pathway+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Coronavirus disease - COVID-19+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia-Ribosome+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Akkermansia	RANTES	Akkermansia+Systemic lupus erythematosus-Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.23	0.0757	no	no	no	no	no	up	HC
Bifidobacterium	RANTES	Bifidobacterium+TXB2+blood+RANTES	Indirect	Genus	serum_cytokines	0.105	0.0757	no	dn	no	no	no	up	HC
Ruminococcus	RANTES	Ruminococcus+Thermogenesis-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	HC
Ruminococcus	RANTES	Ruminococcus+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.335	0.0757	no	no	no	no	no	up	HC
GCDCA+blood	RANTES	GCDCA+blood-iso-DCA+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.31	0.0757	no	no	no	no	no	up	HC
GCDCA+blood	RANTES	GCDCA+blood-UFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.31	0.0757	no	no	no	no	no	up	HC
GCDCA+blood	RANTES	GCDCA+blood+2-hydroxyhippuric acid+urine-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.31	0.0757	no	no	no	no	no	up	HC
GCDCA+blood	RANTES	GCDCA+blood-PUFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.31	0.0757	no	no	no	no	no	up	HC
GCDCA+blood	RANTES	GCDCA+blood-L-Phenylalanine+urine+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.31	0.0757	no	no	no	no	no	up	HC
GCDCA+blood	RANTES	GCDCA+blood-iso-DCA+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.31	0.0757	no	no	no	no	no	up	HC
GCDCA+blood	RANTES	GCDCA+blood-UFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.31	0.0757	no	no	no	no	no	up	HC
GCDCA+blood	RANTES	GCDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.31	0.0757	no	no	no	no	no	up	HC
GCDCA+blood	RANTES	GCDCA+blood-PUFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.31	0.0757	no	no	no	no	no	up	HC
GCDCA+blood	RANTES	GCDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.31	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	[Prevotella]-Gap junction-C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	[Prevotella]-Aldosterone synthesis and secretion+Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	[Prevotella]-18:0/22:6-PC+blood+TXB2+blood+RANTES	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	[Prevotella]-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	[Prevotella]-GnRH signaling pathway+Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	[Prevotella]-Aldosterone synthesis and secretion+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	[Prevotella]-Morphine addiction+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	[Prevotella]-Aldosterone synthesis and secretion+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	[Prevotella]-GnRH signaling pathway+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	"[Prevotella]-Aldosterone synthesis and secretion+Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	"[Prevotella]-GnRH signaling pathway+Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	[Prevotella]-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	[Prevotella]-GnRH signaling pathway+Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	[Prevotella]-Aldosterone synthesis and secretion+Prion disease-RANTES	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	[Prevotella]-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	[Prevotella]-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	[Prevotella]-18:0/22:6-PC+blood+22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	"[Prevotella]-Growth hormone synthesis, secretion and action+PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES"	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	[Prevotella]-Aldosterone synthesis and secretion+Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	[Prevotella]-GnRH signaling pathway+Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
[Prevotella]	RANTES	"[Prevotella]-Growth hormone synthesis, secretion and action+Prostate cancer-RANTES"	Indirect	Genus	serum_cytokines	0.367	0.0757	no	no	no	no	no	up	HC
ACA+blood	RANTES	ACA+blood-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.338	0.0757	no	no	no	no	no	up	HC
ACA+blood	RANTES	ACA+blood-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.338	0.0757	no	no	no	no	no	up	HC
DCA+stool	RANTES	DCA+stool-8-HETE+blood+TXB2+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.195	0.0757	no	no	no	no	no	up	HC
DCA+stool	RANTES	DCA+stool-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.195	0.0757	no	no	no	no	no	up	HC
DCA+stool	RANTES	DCA+stool-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.195	0.0757	no	no	no	no	no	up	HC
DCA+stool	RANTES	DCA+stool-DL-methionine sulfoxide+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.195	0.0757	no	no	no	no	no	up	HC
2-hydroxyhippuric acid+urine	RANTES	2-hydroxyhippuric acid+urine-L-Tryptophan+urine-RANTES	Indirect	urine_cometabolism	serum_cytokines	0.215	0.0757	no	no	no	no	no	up	HC
2-hydroxyhippuric acid+urine	RANTES	2-hydroxyhippuric acid+urine-L-Tyrosine+urine-RANTES	Indirect	urine_cometabolism	serum_cytokines	0.215	0.0757	no	no	no	no	no	up	HC
Butyric acid+stool	RANTES	Butyric acid+stool+L-Tyrosine+urine-RANTES	Indirect	stool_scfa	serum_cytokines	0.102	0.0757	dn	no	no	no	no	up	HC
4-hydroxybenzoic acid+stool	RANTES	4-hydroxybenzoic acid+stool-L-Homocystine+blood-TXB2+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.0757	no	dn	no	no	no	up	HC
4-hydroxybenzoic acid+stool	RANTES	4-hydroxybenzoic acid+stool-20:5n3+blood+22:6n3+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.0757	no	dn	no	no	no	up	HC
4-hydroxybenzoic acid+stool	RANTES	4-hydroxybenzoic acid+stool-L-Homocystine+blood-IP-10+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.0757	no	dn	no	no	no	up	HC
4-hydroxybenzoic acid+stool	RANTES	4-hydroxybenzoic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.0757	no	dn	no	no	no	up	HC
GCA+blood	RANTES	GCA+blood-iso-DCA+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.16	0.0757	no	no	no	no	no	up	HC
GCA+blood	RANTES	GCA+blood-L-Phenylalanine+urine+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.16	0.0757	no	no	no	no	no	up	HC
GCA+blood	RANTES	GCA+blood+2-hydroxyhippuric acid+urine-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.16	0.0757	no	no	no	no	no	up	HC
GCA+blood	RANTES	GCA+blood-iso-DCA+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.16	0.0757	no	no	no	no	no	up	HC
GCA+blood	RANTES	GCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.16	0.0757	no	no	no	no	no	up	HC
GCA+blood	RANTES	GCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.16	0.0757	no	no	no	no	no	up	HC
ACA+stool	RANTES	ACA+stool+UFA%+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.417	0.0757	no	no	no	no	no	up	HC
ACA+stool	RANTES	ACA+stool+UFA%+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.417	0.0757	no	no	no	no	no	up	HC
CDCA+blood	RANTES	CDCA+blood+2-hydroxyhippuric acid+urine-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.506	0.0757	no	no	no	no	no	up	HC
CDCA+blood	RANTES	CDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.506	0.0757	no	no	no	no	no	up	HC
capric acid C6+blood	RANTES	capric acid C6+blood-Cystine+blood+UFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.433	0.0757	no	no	no	no	no	up	HC
capric acid C6+blood	RANTES	capric acid C6+blood-Cystine+blood+UFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.433	0.0757	no	no	no	no	no	up	HC
capric acid C6+blood	RANTES	capric acid C6+blood-Cystine+blood+Serine+blood+L-Tyrosine+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.433	0.0757	no	no	no	no	no	up	HC
capric acid C6+blood	RANTES	capric acid C6+blood-Cystine+blood+L-Aspartic acid+blood+TXB2+blood+RANTES	Indirect	serum_scfa	serum_cytokines	0.433	0.0757	no	no	no	no	no	up	HC
Prevotella	RANTES	Prevotella-L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.287	0.0757	no	no	no	no	no	up	HC
TCA+blood	RANTES	TCA+blood+TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.339	0.0757	no	no	no	no	no	up	HC
TCA+blood	RANTES	TCA+blood+TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.339	0.0757	no	no	no	no	no	up	HC
iso-DCA+blood	RANTES	iso-DCA+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.38	0.0757	no	no	no	no	no	up	HC
iso-DCA+blood	RANTES	iso-DCA+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.38	0.0757	no	no	no	no	no	up	HC
HCA+stool	RANTES	HCA+stool-L-Homocystine+blood-TXB2+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
HCA+stool	RANTES	HCA+stool-L-Homocystine+blood-IP-10+RANTES	Indirect	stool_bileacids	serum_cytokines	0.155	0.0757	no	no	no	no	no	up	HC
Roseburia	RANTES	Roseburia-Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.495	0.0757	no	no	no	no	no	up	HC
Roseburia	RANTES	Roseburia-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.495	0.0757	no	no	no	no	no	up	HC
Roseburia	RANTES	Roseburia-T cell receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.495	0.0757	no	no	no	no	no	up	HC
Roseburia	RANTES	Roseburia-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.495	0.0757	no	no	no	no	no	up	HC
Roseburia	RANTES	Roseburia+TXB2+blood+RANTES	Indirect	Genus	serum_cytokines	0.495	0.0757	no	no	no	no	no	up	HC
Roseburia	RANTES	Roseburia-Neurotrophin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.495	0.0757	no	no	no	no	no	up	HC
12-ketoDCA+stool	RANTES	12-ketoDCA+stool-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	HC
12-ketoDCA+stool	RANTES	12-ketoDCA+stool-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.505	0.0757	no	no	no	no	no	up	HC
GLCA+blood	RANTES	GLCA+blood+L-Glutamine+blood+SFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.319	0.0757	no	no	no	no	no	up	HC
GLCA+blood	RANTES	GLCA+blood+L-Glutamine+blood+Serine+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.319	0.0757	no	no	no	no	no	up	HC
GLCA+blood	RANTES	GLCA+blood+L-Glutamine+blood+PUFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.319	0.0757	no	no	no	no	no	up	HC
GLCA+blood	RANTES	GLCA+blood+L-Glutamine+blood+UFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.319	0.0757	no	no	no	no	no	up	HC
GLCA+blood	RANTES	GLCA+blood+LCA+blood-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.319	0.0757	no	no	no	no	no	up	HC
GLCA+blood	RANTES	GLCA+blood+iso-LCA+blood-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.319	0.0757	no	no	no	no	no	up	HC
GLCA+blood	RANTES	GLCA+blood+L-Glutamine+blood+SFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.319	0.0757	no	no	no	no	no	up	HC
GLCA+blood	RANTES	GLCA+blood+L-Glutamine+blood+PUFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.319	0.0757	no	no	no	no	no	up	HC
GLCA+blood	RANTES	GLCA+blood+L-Glutamine+blood+UFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.319	0.0757	no	no	no	no	no	up	HC
GLCA+blood	RANTES	GLCA+blood+LCA+blood-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.319	0.0757	no	no	no	no	no	up	HC
GLCA+blood	RANTES	GLCA+blood+iso-LCA+blood-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.319	0.0757	no	no	no	no	no	up	HC
GLCA+blood	RANTES	GLCA+blood+L-Glutamine+blood-Homovanillic acid+urine-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.319	0.0757	no	no	no	no	no	up	HC
L-Tryptophan+stool	RANTES	L-Tryptophan+stool+16:0/22:6-PE+blood-L-Tyrosine+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0757	no	no	no	no	no	up	HC
L-Tryptophan+stool	RANTES	L-Tryptophan+stool+18:1/18:1-PE+blood-L-Tyrosine+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0757	no	no	no	no	no	up	HC
L-Tryptophan+stool	RANTES	L-Tryptophan+stool+16:0/22:6-PE+blood-L-Tryptophan+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0757	no	no	no	no	no	up	HC
L-Tryptophan+stool	RANTES	L-Tryptophan+stool+18:1/18:1-PE+blood-L-Tryptophan+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0757	no	no	no	no	no	up	HC
L-Tryptophan+stool	RANTES	L-Tryptophan+stool+Phenylacetic acid+stool-22:6n3+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0757	no	no	no	no	no	up	HC
CA+blood	RANTES	CA+blood-MUFA+blood-PUFA/MUFA+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.606	0.0757	no	no	no	no	no	up	HC
CA+blood	RANTES	CA+blood+LCA+blood-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.606	0.0757	no	no	no	no	no	up	HC
CA+blood	RANTES	CA+blood+CDCA+blood+2-hydroxyhippuric acid+urine-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.606	0.0757	no	no	no	no	no	up	HC
CA+blood	RANTES	CA+blood+HCA+blood+2-hydroxyhippuric acid+urine-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.606	0.0757	no	no	no	no	no	up	HC
CA+blood	RANTES	CA+blood+LCA+blood-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.606	0.0757	no	no	no	no	no	up	HC
CA+blood	RANTES	CA+blood+CDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.606	0.0757	no	no	no	no	no	up	HC
CA+blood	RANTES	CA+blood+HCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.606	0.0757	no	no	no	no	no	up	HC
GUDCA+stool	RANTES	GUDCA+stool+Phenylacetic acid+stool-22:6n3+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.0085	0.0757	no	dn	no	no	no	up	HC
L-Phenylalanine+stool	RANTES	L-Phenylalanine+stool+Phenylacetic acid+stool-22:6n3+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0757	no	no	no	no	no	up	HC
L-Phenylalanine+stool	RANTES	L-Phenylalanine+stool+18:1/18:1-PE+blood-L-Tyrosine+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0757	no	no	no	no	no	up	HC
L-Phenylalanine+stool	RANTES	L-Phenylalanine+stool+16:0/22:6-PE+blood-L-Tyrosine+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0757	no	no	no	no	no	up	HC
L-Phenylalanine+stool	RANTES	L-Phenylalanine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0757	no	no	no	no	no	up	HC
L-Phenylalanine+stool	RANTES	L-Phenylalanine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0757	no	no	no	no	no	up	HC
butyric acid C4+blood	RANTES	butyric acid C4+blood+Cystine+blood+UFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.407	0.0757	no	no	no	no	no	up	HC
butyric acid C4+blood	RANTES	butyric acid C4+blood+Cystine+blood+L-Aspartic acid+blood+TXB2+blood+RANTES	Indirect	serum_scfa	serum_cytokines	0.407	0.0757	no	no	no	no	no	up	HC
butyric acid C4+blood	RANTES	butyric acid C4+blood+Cystine+blood+Serine+blood+L-Tyrosine+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.407	0.0757	no	no	no	no	no	up	HC
butyric acid C4+blood	RANTES	butyric acid C4+blood+Cystine+blood+UFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.407	0.0757	no	no	no	no	no	up	HC
butyric acid C4+blood	RANTES	butyric acid C4+blood+iso-heptanoic acid C7+blood-L-Histidine+blood+L-Tyrosine+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.407	0.0757	no	no	no	no	no	up	HC
GCA+stool	RANTES	GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0757	no	no	no	no	no	up	HC
GCA+stool	RANTES	GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0757	no	no	no	no	no	up	HC
GCA+stool	RANTES	GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0757	no	no	no	no	no	up	HC
GCA+stool	RANTES	GCA+stool+16:0/18:0-PS+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0757	no	no	no	no	no	up	HC
GCA+stool	RANTES	GCA+stool+18:0/22:6-PE+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0757	no	no	no	no	no	up	HC
GCA+stool	RANTES	GCA+stool+16:0/22:6-PE+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0757	no	no	no	no	no	up	HC
GCA+stool	RANTES	GCA+stool+GDCA+stool-TXB2+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0757	no	no	no	no	no	up	HC
Coprococcus	RANTES	Coprococcus+Primary immunodeficiency-Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	HC
Coprococcus	RANTES	Coprococcus+Lachnospira-L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	HC
Coprococcus	RANTES	Coprococcus-18:1-LPC+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	HC
Coprococcus	RANTES	Coprococcus+Homovanillic acid+urine-L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	HC
Coprococcus	RANTES	Coprococcus-Lysosome+C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	HC
Coprococcus	RANTES	Coprococcus+16:0/20:5-PC+blood+22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	HC
Coprococcus	RANTES	Coprococcus+16:0/20:4-PI+blood+22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	HC
Coprococcus	RANTES	Coprococcus+20:5n3+blood+22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	HC
Coprococcus	RANTES	Coprococcus-18:1-LPC+blood-22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	HC
Coprococcus	RANTES	Coprococcus-Phenylacetic acid+stool-22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	HC
Coprococcus	RANTES	Coprococcus-Lysosome-PI3K-Akt signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	HC
Coprococcus	RANTES	Coprococcus+Ribosome biogenesis in eukaryotes+PI3K-Akt signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.612	0.0757	no	no	no	no	no	up	HC
Oscillospira	RANTES	Oscillospira-Ras signaling pathway+Neurotrophin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.62	0.0757	no	no	no	no	no	up	HC
Oscillospira	RANTES	Oscillospira+20:5n3+blood+22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.62	0.0757	no	no	no	no	no	up	HC
Oscillospira	RANTES	Oscillospira+L-Homocystine+blood-IP-10+RANTES	Indirect	Genus	serum_cytokines	0.62	0.0757	no	no	no	no	no	up	HC
Oscillospira	RANTES	Oscillospira+L-Homocystine+blood-TXB2+blood+RANTES	Indirect	Genus	serum_cytokines	0.62	0.0757	no	no	no	no	no	up	HC
Oscillospira	RANTES	Oscillospira-Ras signaling pathway+Signaling pathways regulating pluripotency of stem cells-RANTES	Indirect	Genus	serum_cytokines	0.62	0.0757	no	no	no	no	no	up	HC
Oscillospira	RANTES	Oscillospira-Homovanillic acid+urine-L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.62	0.0757	no	no	no	no	no	up	HC
HCA+blood	RANTES	HCA+blood+2-hydroxyhippuric acid+urine-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.544	0.0757	no	no	no	no	no	up	HC
HCA+blood	RANTES	HCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.544	0.0757	no	no	no	no	no	up	HC
iso-LCA+stool	RANTES	iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.72	0.0757	no	no	no	no	no	up	HC
iso-LCA+stool	RANTES	iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.72	0.0757	no	no	no	no	no	up	HC
iso-LCA+stool	RANTES	iso-LCA+stool-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.72	0.0757	no	no	no	no	no	up	HC
2-methyl-butyric acid m-C4+blood	RANTES	2-methyl-butyric acid m-C4+blood+20:1+blood-22:6n3+blood+RANTES	Indirect	serum_scfa	serum_cytokines	0.262	0.0757	no	no	no	no	no	up	HC
DCA+blood	RANTES	DCA+blood+GUDCA+blood-PUFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	HC
DCA+blood	RANTES	DCA+blood+GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	HC
DCA+blood	RANTES	DCA+blood+GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	HC
DCA+blood	RANTES	DCA+blood+GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	HC
DCA+blood	RANTES	DCA+blood+GUDCA+blood-UFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	HC
DCA+blood	RANTES	DCA+blood+GUDCA+blood+TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	HC
DCA+blood	RANTES	DCA+blood+GUDCA+blood-PUFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	HC
DCA+blood	RANTES	DCA+blood+GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	HC
DCA+blood	RANTES	DCA+blood+GUDCA+blood-L-Phenylalanine+urine+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	HC
DCA+blood	RANTES	DCA+blood+GUDCA+blood-iso-DCA+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	HC
DCA+blood	RANTES	DCA+blood+GUDCA+blood-UFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	HC
DCA+blood	RANTES	DCA+blood+GUDCA+blood+TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.122	0.0757	no	no	no	no	no	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	RANTES	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/22:6-PC+blood+TXB2+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0757	no	no	no	no	no	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	RANTES	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/22:6-PC+blood+22:6n3+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0757	no	no	no	no	no	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	RANTES	3-(3-Hydroxyphenyl)propanoic acid+stool+14:0/18:2-PC+blood+22:6n3+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0757	no	no	no	no	no	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	RANTES	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/20:3-PC+blood+22:6n3+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0757	no	no	no	no	no	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	RANTES	3-(3-Hydroxyphenyl)propanoic acid+stool+14:0+blood+22:6n3+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0757	no	no	no	no	no	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	RANTES	3-(3-Hydroxyphenyl)propanoic acid+stool+20:2/18:0-PC+blood+22:6n3+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0757	no	no	no	no	no	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	RANTES	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0+blood+22:6n3+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0757	no	no	no	no	no	up	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	RANTES	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-RANTES"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.0757	up	up	no	no	no	up	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	RANTES	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IP-10+RANTES"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.0757	up	up	no	no	no	up	HC
GLCA+stool	RANTES	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.617	0.0757	no	no	no	no	no	up	HC
GLCA+stool	RANTES	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.617	0.0757	no	no	no	no	no	up	HC
GLCA+stool	RANTES	GLCA+stool-iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.617	0.0757	no	no	no	no	no	up	HC
GLCA+stool	RANTES	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.617	0.0757	no	no	no	no	no	up	HC
GLCA+stool	RANTES	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.617	0.0757	no	no	no	no	no	up	HC
GLCA+stool	RANTES	GLCA+stool-LCA+stool-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.617	0.0757	no	no	no	no	no	up	HC
GLCA+stool	RANTES	GLCA+stool-iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.617	0.0757	no	no	no	no	no	up	HC
GLCA+stool	RANTES	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.617	0.0757	no	no	no	no	no	up	HC
GLCA+stool	RANTES	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.617	0.0757	no	no	no	no	no	up	HC
GLCA+stool	RANTES	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.617	0.0757	no	no	no	no	no	up	HC
GLCA+stool	RANTES	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.617	0.0757	no	no	no	no	no	up	HC
GLCA+stool	RANTES	GLCA+stool-LCA+stool-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.617	0.0757	no	no	no	no	no	up	HC
GLCA+stool	RANTES	GLCA+stool-iso-LCA+stool-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.617	0.0757	no	no	no	no	no	up	HC
Indole-3-Acetic acid+stool	RANTES	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-22:6n3+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-18:2/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-PUFA%+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-16:0/18:1-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-18:1/18:1-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-18:0/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-UFA%+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-SFA%+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-iso-DCA+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-20:0+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-16:0/18:2-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-18:1/18:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-18:1/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-18:2/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-PUFA%+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-16:0/18:1-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-18:1/18:1-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-18:0/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-UFA%+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-SFA%+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-iso-DCA+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-16:0/18:2-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-18:1/18:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-18:1/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool+16:0/20:4-PI+blood+22:6n3+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-18:1/18:1-PC+blood-22:6n3+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
TCA+stool	RANTES	TCA+stool-20:0+blood-22:6n3+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.458	0.0757	no	no	no	no	no	up	HC
HDCA+stool	RANTES	HDCA+stool+16:0/20:4-PC+blood-22:6n3+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	HC
HDCA+stool	RANTES	HDCA+stool+20:3/16:0-PC+blood-22:6n3+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	HC
HDCA+stool	RANTES	HDCA+stool+16:0/20:4-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	HC
HDCA+stool	RANTES	HDCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	HC
HDCA+stool	RANTES	HDCA+stool-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	HC
HDCA+stool	RANTES	HDCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	HC
HDCA+stool	RANTES	HDCA+stool+20:3/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	HC
HDCA+stool	RANTES	HDCA+stool+16:0/20:4-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	HC
HDCA+stool	RANTES	HDCA+stool+16:0/18:1-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	HC
HDCA+stool	RANTES	HDCA+stool-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	HC
HDCA+stool	RANTES	HDCA+stool+18:0/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	HC
HDCA+stool	RANTES	HDCA+stool+20:3/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.176	0.0757	no	no	no	no	no	up	HC
Lachnospira	RANTES	Lachnospira-L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.279	0.0757	no	no	no	no	no	up	HC
isobutyric acid C4+blood	RANTES	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.0151	0.0757	up	up	no	no	no	up	HC
isobutyric acid C4+blood	RANTES	isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood-PUFA/MUFA+blood+L-Tyrosine+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.0151	0.0757	up	up	no	no	no	up	HC
isobutyric acid C4+blood	RANTES	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+Serine+blood+L-Tyrosine+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.0151	0.0757	up	up	no	no	no	up	HC
isobutyric acid C4+blood	RANTES	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.0151	0.0757	up	up	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood+TXB2+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood-TXB2+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool+18:0/20:5-PC+blood+UFA%+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool+18:0/20:5-PC+blood+PUFA%+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool+18:0/20:5-PC+blood+18:1/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool+18:0/20:5-PC+blood+18:1/18:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool+18:0/20:5-PC+blood+18:2/20:4-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool+18:0/20:5-PC+blood+UFA%+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool+18:0/20:5-PC+blood+PUFA%+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool+18:0/20:5-PC+blood+18:1/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool+18:0/20:5-PC+blood+18:1/18:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool-22:6n3+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool-22:6n3+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool+18:0/20:5-PC+blood+22:0/16:0-PE+blood+22:6n3+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool+18:0/20:5-PC+blood+20:1/20:4-PC+blood+22:6n3+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
GCDCA+stool	RANTES	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood+22:6n3+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0757	no	dn	no	no	no	up	HC
5-Hydroxytryptamine+stool	RANTES	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0757	dn	dn	no	no	no	up	HC
5-Hydroxytryptamine+stool	RANTES	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0757	dn	dn	no	no	no	up	HC
5-Hydroxytryptamine+stool	RANTES	5-Hydroxytryptamine+stool+GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0757	dn	dn	no	no	no	up	HC
5-Hydroxytryptamine+stool	RANTES	5-Hydroxytryptamine+stool+GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0757	dn	dn	no	no	no	up	HC
5-Hydroxytryptamine+stool	RANTES	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0757	dn	dn	no	no	no	up	HC
5-Hydroxytryptamine+stool	RANTES	5-Hydroxytryptamine+stool+GCA+stool+16:0/22:6-PE+blood-L-Tyrosine+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0757	dn	dn	no	no	no	up	HC
5-Hydroxytryptamine+stool	RANTES	5-Hydroxytryptamine+stool+GCA+stool+16:0/18:0-PS+blood-L-Tyrosine+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0757	dn	dn	no	no	no	up	HC
5-Hydroxytryptamine+stool	RANTES	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-L-Tyrosine+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0757	dn	dn	no	no	no	up	HC
5-Hydroxytryptamine+stool	RANTES	5-Hydroxytryptamine+stool+GCA+stool+GDCA+stool-TXB2+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0757	dn	dn	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Gap junction-C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Long-term depression+Prion disease-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Pancreatic secretion+Prion disease-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Aldosterone synthesis and secretion+Prion disease-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Endocrine resistance+Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Long-term depression+Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Endocrine resistance+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Long-term depression+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter+Arginine and proline metabolism-Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Pancreatic secretion+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Aldosterone synthesis and secretion+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Cushing syndrome+Parkinson disease-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	"Odoribacter-Endocrine resistance+Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	"Odoribacter-Long-term depression+Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	"Odoribacter-Aldosterone synthesis and secretion+Parathyroid hormone synthesis, secretion and action-RANTES"	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Endocrine resistance+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Long-term depression+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter+Arginine and proline metabolism-Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Pancreatic secretion+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Cushing syndrome+Pathways of neurodegeneration - multiple diseases-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Endocrine resistance+Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Long-term depression+Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Aldosterone synthesis and secretion+Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Endocrine resistance+Signaling pathways regulating pluripotency of stem cells-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Endocrine resistance+Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Long-term depression+Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Pancreatic secretion+Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Aldosterone synthesis and secretion+Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Cushing syndrome+Alzheimer disease-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Endocrine resistance+Thermogenesis-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter+Arginine and proline metabolism-Thermogenesis-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Endocrine resistance+Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Long-term depression+Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter+Arginine and proline metabolism-Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Pancreatic secretion+Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Cushing syndrome+Amyotrophic lateral sclerosis-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Phospholipase D signaling pathway-PI3K-Akt signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-PUFA/MUFA+blood+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Morphine addiction+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Long-term depression+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Pancreatic secretion+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Aldosterone synthesis and secretion+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Odoribacter	RANTES	Odoribacter-Cushing syndrome+Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.798	0.0757	no	no	no	no	no	up	HC
Isobutyric acid+stool	RANTES	Isobutyric acid+stool+Phenylacetic acid+stool-22:6n3+blood+RANTES	Indirect	stool_scfa	serum_cytokines	0.408	0.0757	no	no	no	no	no	up	HC
Kynurenic acid+stool	RANTES	Kynurenic acid+stool-nutriCA+stool-L-Homocystine+blood-TXB2+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0757	dn	dn	no	no	no	up	HC
Kynurenic acid+stool	RANTES	Kynurenic acid+stool-nutriCA+stool-L-Homocystine+blood-IP-10+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0757	dn	dn	no	no	no	up	HC
Kynurenic acid+stool	RANTES	Kynurenic acid+stool-nutriCA+stool+TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0757	dn	dn	no	no	no	up	HC
Kynurenic acid+stool	RANTES	Kynurenic acid+stool-nutriCA+stool+TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0757	dn	dn	no	no	no	up	HC
L-Tryptophan+urine	RANTES	L-Tryptophan+urine-RANTES	Direct	urine_cometabolism	serum_cytokines	0.226	0.0757	no	no	no	no	no	up	HC
Eggerthella	RANTES	Eggerthella-Faecalibacterium-RANTES	Indirect	Genus	serum_cytokines	0.912	0.0757	no	no	no	no	no	up	HC
Eggerthella	RANTES	Eggerthella+Bacteroides+RANTES	Indirect	Genus	serum_cytokines	0.912	0.0757	no	no	no	no	no	up	HC
Anaerotruncus	RANTES	Anaerotruncus-Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.904	0.0757	no	no	no	no	no	up	HC
Anaerotruncus	RANTES	Anaerotruncus-Gemmiger-Tuberculosis-Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.904	0.0757	no	no	no	no	no	up	HC
Anaerotruncus	RANTES	Anaerotruncus-Gemmiger-Staphylococcus aureus infection-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.904	0.0757	no	no	no	no	no	up	HC
Anaerotruncus	RANTES	Anaerotruncus-Gemmiger-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.904	0.0757	no	no	no	no	no	up	HC
Anaerotruncus	RANTES	Anaerotruncus-Gemmiger-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.904	0.0757	no	no	no	no	no	up	HC
Anaerostipes	RANTES	Anaerostipes-Th17 cell differentiation-TXB2+blood+RANTES	Indirect	Genus	serum_cytokines	0.568	0.0757	no	no	no	no	no	up	HC
Anaerostipes	RANTES	Anaerostipes+L-Phenylalanine+urine+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.568	0.0757	no	no	no	no	no	up	HC
Anaerostipes	RANTES	Anaerostipes-20:1+blood-22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.568	0.0757	no	no	no	no	no	up	HC
Anaerostipes	RANTES	Anaerostipes-20:0+blood-22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.568	0.0757	no	no	no	no	no	up	HC
Anaerostipes	RANTES	Anaerostipes-Th1 and Th2 cell differentiation-22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.568	0.0757	no	no	no	no	no	up	HC
Anaerostipes	RANTES	Anaerostipes-18:1-LPC+blood-22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.568	0.0757	no	no	no	no	no	up	HC
Anaerostipes	RANTES	Anaerostipes-Th17 cell differentiation-22:6n3+blood+RANTES	Indirect	Genus	serum_cytokines	0.568	0.0757	no	no	no	no	no	up	HC
Anaerostipes	RANTES	Anaerostipes+L-Phenylalanine+urine+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.568	0.0757	no	no	no	no	no	up	HC
Anaerostipes	RANTES	Anaerostipes-20:0+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.568	0.0757	no	no	no	no	no	up	HC
Anaerostipes	RANTES	Anaerostipes-18:1-LPC+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.568	0.0757	no	no	no	no	no	up	HC
Anaerostipes	RANTES	Anaerostipes-Th1 and Th2 cell differentiation+Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.568	0.0757	no	no	no	no	no	up	HC
Anaerostipes	RANTES	Anaerostipes-Th17 cell differentiation+Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.568	0.0757	no	no	no	no	no	up	HC
Isovaleric acid+stool	RANTES	Isovaleric acid+stool+Phenylacetic acid+stool-22:6n3+blood+RANTES	Indirect	stool_scfa	serum_cytokines	0.343	0.0757	no	no	no	no	no	up	HC
Paraprevotella	RANTES	Paraprevotella-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	HC
Paraprevotella	RANTES	Paraprevotella-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	HC
Paraprevotella	RANTES	Paraprevotella-C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	HC
Paraprevotella	RANTES	Paraprevotella-Relaxin signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.118	0.0757	no	no	no	no	no	up	HC
Homovanillic acid+urine	RANTES	Homovanillic acid+urine-L-Tryptophan+urine-RANTES	Indirect	urine_cometabolism	serum_cytokines	0.45	0.0757	no	no	no	no	no	up	HC
TDCA+blood	RANTES	TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.155	0.0757	no	up	no	no	no	up	HC
TDCA+blood	RANTES	TDCA+blood+2-hydroxyhippuric acid+urine-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.155	0.0757	no	up	no	no	no	up	HC
L-Tyrosine+urine	RANTES	L-Tyrosine+urine-RANTES	Direct	urine_cometabolism	serum_cytokines	0.45	0.0757	no	no	no	no	no	up	HC
iso-LCA+blood	RANTES	iso-LCA+blood-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.507	0.0757	no	no	no	no	no	up	HC
iso-LCA+blood	RANTES	iso-LCA+blood-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.507	0.0757	no	no	no	no	no	up	HC
¦Ø-MCA+stool	RANTES	¦Ø-MCA+stool-Butyric acid+stool+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.919	0.0757	no	no	no	no	no	up	HC
Phenylacetic acid+stool	RANTES	Phenylacetic acid+stool-22:6n3+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.785	0.0757	no	no	no	no	no	up	HC
Gemmiger	RANTES	Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.595	0.0757	no	no	no	no	no	up	HC
Gemmiger	RANTES	Gemmiger-Tuberculosis-Diabetic cardiomyopathy-RANTES	Indirect	Genus	serum_cytokines	0.595	0.0757	no	no	no	no	no	up	HC
Gemmiger	RANTES	Gemmiger-Staphylococcus aureus infection-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.595	0.0757	no	no	no	no	no	up	HC
Gemmiger	RANTES	Gemmiger-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.595	0.0757	no	no	no	no	no	up	HC
Gemmiger	RANTES	Gemmiger-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.595	0.0757	no	no	no	no	no	up	HC
GDCA+stool	RANTES	GDCA+stool-TXB2+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.656	0.0757	no	no	no	no	no	up	HC
L-Tyrosine+stool	RANTES	L-Tyrosine+stool+18:1/18:1-PE+blood-L-Tyrosine+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0757	no	no	no	no	no	up	HC
L-Tyrosine+stool	RANTES	L-Tyrosine+stool+16:0/22:6-PE+blood-L-Tyrosine+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0757	no	no	no	no	no	up	HC
L-Tyrosine+stool	RANTES	L-Tyrosine+stool+PUFA%+blood+L-Tyrosine+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0757	no	no	no	no	no	up	HC
L-Tyrosine+stool	RANTES	L-Tyrosine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0757	no	no	no	no	no	up	HC
L-Tyrosine+stool	RANTES	L-Tyrosine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0757	no	no	no	no	no	up	HC
L-Tyrosine+stool	RANTES	L-Tyrosine+stool+PUFA%+blood+L-Tryptophan+urine-RANTES	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0757	no	no	no	no	no	up	HC
L-Tyrosine+stool	RANTES	L-Tyrosine+stool+8-HETE+blood+TXB2+blood+RANTES	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0757	no	no	no	no	no	up	HC
CDCA+stool	RANTES	CDCA+stool+TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.663	0.0757	no	no	no	no	no	up	HC
CDCA+stool	RANTES	CDCA+stool+TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.663	0.0757	no	no	no	no	no	up	HC
CA+stool	RANTES	CA+stool+GDCA+stool-TXB2+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.827	0.0757	no	no	no	no	no	up	HC
CA+stool	RANTES	CA+stool+TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.827	0.0757	no	no	no	no	no	up	HC
CA+stool	RANTES	CA+stool-18:1/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.827	0.0757	no	no	no	no	no	up	HC
CA+stool	RANTES	CA+stool+TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.827	0.0757	no	no	no	no	no	up	HC
CA+stool	RANTES	CA+stool-18:1/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.827	0.0757	no	no	no	no	no	up	HC
HDCA+blood	RANTES	HDCA+blood+UFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.483	0.0757	no	no	no	no	no	up	HC
HDCA+blood	RANTES	HDCA+blood+L-Histidine+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.483	0.0757	no	no	no	no	no	up	HC
HDCA+blood	RANTES	HDCA+blood+SFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.483	0.0757	no	no	no	no	no	up	HC
HDCA+blood	RANTES	HDCA+blood+PUFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.483	0.0757	no	no	no	no	no	up	HC
HDCA+blood	RANTES	HDCA+blood+PUFA/MUFA+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.483	0.0757	no	no	no	no	no	up	HC
HDCA+blood	RANTES	HDCA+blood+L-Aspartic acid+blood+TXB2+blood+RANTES	Indirect	serum_bileacids	serum_cytokines	0.483	0.0757	no	no	no	no	no	up	HC
HDCA+blood	RANTES	HDCA+blood+UFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.483	0.0757	no	no	no	no	no	up	HC
HDCA+blood	RANTES	HDCA+blood+SFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.483	0.0757	no	no	no	no	no	up	HC
HDCA+blood	RANTES	HDCA+blood+PUFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.483	0.0757	no	no	no	no	no	up	HC
UDCA+stool	RANTES	UDCA+stool+18:3n3+blood+AA+blood+TXB2+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.266	0.0757	no	no	no	no	no	up	HC
UDCA+stool	RANTES	UDCA+stool+18:3n3+blood+UFA%+blood+L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.266	0.0757	no	no	no	no	no	up	HC
UDCA+stool	RANTES	UDCA+stool-iso-LCA+blood-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.266	0.0757	no	no	no	no	no	up	HC
UDCA+stool	RANTES	UDCA+stool-TMAO+blood-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.266	0.0757	no	no	no	no	no	up	HC
UDCA+stool	RANTES	UDCA+stool+16:0/18:3-PC+blood-2-hydroxyhippuric acid+urine-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.266	0.0757	no	no	no	no	no	up	HC
UDCA+stool	RANTES	UDCA+stool+18:3n3+blood-2-hydroxyhippuric acid+urine-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.266	0.0757	no	no	no	no	no	up	HC
UDCA+stool	RANTES	UDCA+stool+18:3n3+blood+UFA%+blood+L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.266	0.0757	no	no	no	no	no	up	HC
UDCA+stool	RANTES	UDCA+stool-iso-LCA+blood-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.266	0.0757	no	no	no	no	no	up	HC
UDCA+stool	RANTES	UDCA+stool-TMAO+blood-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.266	0.0757	no	no	no	no	no	up	HC
UDCA+stool	RANTES	UDCA+stool+16:0/18:3-PC+blood-2-hydroxyhippuric acid+urine-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.266	0.0757	no	no	no	no	no	up	HC
UDCA+stool	RANTES	UDCA+stool+18:3n3+blood-2-hydroxyhippuric acid+urine-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.266	0.0757	no	no	no	no	no	up	HC
LCA+blood	RANTES	LCA+blood-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.884	0.0757	no	no	no	no	no	up	HC
LCA+blood	RANTES	LCA+blood-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.884	0.0757	no	no	no	no	no	up	HC
nutriCA+stool	RANTES	nutriCA+stool+TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.481	0.0757	no	no	no	no	no	up	HC
nutriCA+stool	RANTES	nutriCA+stool+TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	stool_bileacids	serum_cytokines	0.481	0.0757	no	no	no	no	no	up	HC
nutriCA+stool	RANTES	nutriCA+stool-L-Homocystine+blood-TXB2+blood+RANTES	Indirect	stool_bileacids	serum_cytokines	0.481	0.0757	no	no	no	no	no	up	HC
nutriCA+stool	RANTES	nutriCA+stool-L-Homocystine+blood-IP-10+RANTES	Indirect	stool_bileacids	serum_cytokines	0.481	0.0757	no	no	no	no	no	up	HC
GDCA+blood	RANTES	GDCA+blood+TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.632	0.0757	no	no	no	no	no	up	HC
GDCA+blood	RANTES	GDCA+blood+TDCA+blood+2-hydroxyhippuric acid+urine-L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.632	0.0757	no	no	no	no	no	up	HC
P-hydroxyhippuric acid+urine	RANTES	P-hydroxyhippuric acid+urine-FGF basic+IL-17A-RANTES	Indirect	urine_cometabolism	serum_cytokines	0.436	0.0757	no	no	no	no	no	up	HC
P-hydroxyhippuric acid+urine	RANTES	P-hydroxyhippuric acid+urine-FGF basic-IP-10+RANTES	Indirect	urine_cometabolism	serum_cytokines	0.436	0.0757	no	no	no	no	no	up	HC
acetic acid C2+blood	RANTES	acetic acid C2+blood-LCA+blood-TUDCA+blood-L-Tyrosine+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.000193	0.0757	up	dn	no	no	no	up	HC
acetic acid C2+blood	RANTES	acetic acid C2+blood-HCA+blood+2-hydroxyhippuric acid+urine-L-Tyrosine+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.000193	0.0757	up	dn	no	no	no	up	HC
acetic acid C2+blood	RANTES	acetic acid C2+blood-LCA+blood-TUDCA+blood-L-Tryptophan+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.000193	0.0757	up	dn	no	no	no	up	HC
acetic acid C2+blood	RANTES	acetic acid C2+blood-HCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.000193	0.0757	up	dn	no	no	no	up	HC
isovaleric acid iso-C5+blood	RANTES	isovaleric acid iso-C5+blood+Sarcosine+blood-L-Phenylalanine+urine+L-Tyrosine+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.117	0.0757	no	no	no	no	no	up	HC
isovaleric acid iso-C5+blood	RANTES	isovaleric acid iso-C5+blood+Sarcosine+blood-L-Phenylalanine+urine+L-Tryptophan+urine-RANTES	Indirect	serum_scfa	serum_cytokines	0.117	0.0757	no	no	no	no	no	up	HC
L-Phenylalanine+urine	RANTES	L-Phenylalanine+urine+L-Tyrosine+urine-RANTES	Indirect	urine_cometabolism	serum_cytokines	0.0908	0.0757	no	up	no	no	no	up	HC
L-Phenylalanine+urine	RANTES	L-Phenylalanine+urine+L-Tryptophan+urine-RANTES	Indirect	urine_cometabolism	serum_cytokines	0.0908	0.0757	no	up	no	no	no	up	HC
Clostridium	RANTES	Clostridium-L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	HC
Clostridium	RANTES	Clostridium-L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.925	0.0757	no	no	no	no	no	up	HC
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-18:1-LPC+blood-22:6n3+blood+RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	HC
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-18:2/18:1-PC+blood-22:6n3+blood+RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	HC
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-iso-DCA+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	HC
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-UFA%+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	HC
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-18:2/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	HC
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-iso-DCA+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	HC
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-18:1-LPC+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	HC
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-UFA%+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	HC
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-18:2/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	HC
12-ketoDCA+blood	RANTES	12-ketoDCA+blood-AA+blood+TXB2+blood+RANTES	Indirect	serum_bileacids	serum_cytokines	0.517	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Salivary secretion-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Hepatocellular carcinoma-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Focal adhesion-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Platelet activation-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Oxytocin signaling pathway-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Rap1 signaling pathway-PI3K-Akt signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-16:0-LPC+blood+TXB2+blood+RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Thyroid hormone signaling pathway-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Focal adhesion-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Rap1 signaling pathway-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Leukocyte transendothelial migration-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Platelet activation-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Oxytocin signaling pathway-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-18:2/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-18:2/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Focal adhesion-C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Platelet activation-C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Salivary secretion-Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Focal adhesion-Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Platelet activation-Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Oxytocin signaling pathway-Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Focal adhesion-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Platelet activation-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Oxytocin signaling pathway-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Focal adhesion-TNF signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
Butyricicoccus	RANTES	Butyricicoccus-Platelet activation-TNF signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.852	0.0757	no	no	no	no	no	up	HC
3-Hydroxy-L-kynurenine+urine	RANTES	3-Hydroxy-L-kynurenine+urine+L-Tyrosine+urine-RANTES	Indirect	urine_cometabolism	serum_cytokines	0.401	0.0757	no	no	no	no	no	up	HC
3-Hydroxy-L-kynurenine+urine	RANTES	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine-RANTES	Indirect	urine_cometabolism	serum_cytokines	0.401	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Salivary secretion-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Hepatocellular carcinoma-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Focal adhesion-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Platelet activation-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Oxytocin signaling pathway-PD-L1 expression and PD-1 checkpoint pathway in cancer-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Rap1 signaling pathway-PI3K-Akt signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-16:0-LPC+blood+TXB2+blood+RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Thyroid hormone signaling pathway-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Focal adhesion-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Rap1 signaling pathway-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Leukocyte transendothelial migration-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Platelet activation-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Oxytocin signaling pathway-Insulin resistance-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-18:2/16:0-PC+blood+L-Tyrosine+urine-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-18:2/16:0-PC+blood+L-Tryptophan+urine-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Focal adhesion-C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Platelet activation-C-type lectin receptor signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Salivary secretion-Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Focal adhesion-Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Platelet activation-Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Oxytocin signaling pathway-Chronic myeloid leukemia-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Focal adhesion-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Platelet activation-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Oxytocin signaling pathway-Prostate cancer-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Focal adhesion-TNF signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Wautersiella	RANTES	Wautersiella+Butyricicoccus-Platelet activation-TNF signaling pathway-RANTES	Indirect	Genus	serum_cytokines	0.289	0.0757	no	no	no	no	no	up	HC
Blautia	IL-1ra	Blautia+Peroxisome+Primary immunodeficiency+IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	HC
Blautia	IL-1ra	Blautia-Chemical carcinogenesis - receptor activation+Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	HC
Blautia	IL-1ra	Blautia-Chemical carcinogenesis - receptor activation+L-Phenylalanine+blood-IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	HC
Blautia	IL-1ra	Blautia-Chemical carcinogenesis - receptor activation+L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	HC
Blautia	IL-1ra	Blautia-18:1-LPE+blood+L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	HC
Blautia	IL-1ra	Blautia+16:0/20:5-PC+blood-18:1-LPC+blood-IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	HC
Blautia	IL-1ra	Blautia+16:0/20:5-PC+blood-Betaine+blood-IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	HC
Blautia	IL-1ra	Blautia+16:0/20:5-PC+blood-Choline+blood-IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	HC
Blautia	IL-1ra	Blautia-Ras signaling pathway+Calcium signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	HC
Blautia	IL-1ra	Blautia+Arginine and proline metabolism-Calcium signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	HC
Blautia	IL-1ra	Blautia-Ras signaling pathway+Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	HC
Blautia	IL-1ra	Blautia+Peroxisome-Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	HC
Blautia	IL-1ra	Blautia-Chemical carcinogenesis - receptor activation+Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	HC
Blautia	IL-1ra	Blautia-Cushing syndrome+Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	1.36E-05	0.0288	up	dn	dn	no	up	up	HC
Parabacteroides	IL-1ra	Parabacteroides-Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	4.19E-05	0.0288	no	up	up	no	up	up	HC
Parabacteroides	IL-1ra	Parabacteroides+Carbon metabolism+IL-1ra	Indirect	Genus	serum_cytokines	4.19E-05	0.0288	no	up	up	no	up	up	HC
Parabacteroides	IL-1ra	Parabacteroides+Glycolysis / Gluconeogenesis+IL-1ra	Indirect	Genus	serum_cytokines	4.19E-05	0.0288	no	up	up	no	up	up	HC
Dorea	IL-1ra	Dorea+Legionellosis+IL-1ra	Indirect	Genus	serum_cytokines	0.00362	0.0288	up	no	dn	no	up	up	HC
Faecalibacterium	IL-1ra	Faecalibacterium-Staphylococcus aureus infection-Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.0039	0.0288	no	dn	dn	no	up	up	HC
Faecalibacterium	IL-1ra	Faecalibacterium-Staphylococcus aureus infection-Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.0039	0.0288	no	dn	dn	no	up	up	HC
Faecalibacterium	IL-1ra	Faecalibacterium+4-hydroxybenzoic acid+stool-L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.0039	0.0288	no	dn	dn	no	up	up	HC
isocapric acid iso-C6+blood	IL-1ra	isocapric acid iso-C6+blood+L-Tyrosine+blood-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.0458	0.0288	no	no	dn	no	up	up	HC
Bacteroides	IL-1ra	Bacteroides-L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.000267	0.0288	dn	dn	up	no	up	up	HC
Propionic acid+stool	IL-1ra	Propionic acid+stool-d18:1-22:1-SM+blood-L-Phenylalanine+blood-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.0436	0.0288	dn	no	up	no	up	up	HC
Propionic acid+stool	IL-1ra	Propionic acid+stool+16:0/18:2-PI+blood-18:1-LPC+blood-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.0436	0.0288	dn	no	up	no	up	up	HC
Propionic acid+stool	IL-1ra	Propionic acid+stool+16:0/18:2-PI+blood-20:1+blood-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.0436	0.0288	dn	no	up	no	up	up	HC
[Ruminococcus]	IL-1ra	[Ruminococcus]+16:0/18:3-PC+blood-L-Tryptophan+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.0679	0.0288	no	no	dn	no	up	up	HC
[Ruminococcus]	IL-1ra	[Ruminococcus]+nutriCA+stool-L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.0679	0.0288	no	no	dn	no	up	up	HC
[Ruminococcus]	IL-1ra	[Ruminococcus]-18:0/20:4-PI+blood+18:1-LPC+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.0679	0.0288	no	no	dn	no	up	up	HC
[Ruminococcus]	IL-1ra	[Ruminococcus]-18:0/20:4-PI+blood+L-Tyrosine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.0679	0.0288	no	no	dn	no	up	up	HC
GUDCA+blood	IL-1ra	GUDCA+blood-iso-DCA+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.0766	0.0288	no	no	dn	no	up	up	HC
Acetic acid+stool	IL-1ra	Acetic acid+stool-L-Homocystine+blood-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.0656	0.0288	dn	no	no	no	up	up	HC
Acetic acid+stool	IL-1ra	Acetic acid+stool-Phenylacetic acid+stool-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.0656	0.0288	dn	no	no	no	up	up	HC
Alistipes	IL-1ra	Alistipes-Primary immunodeficiency+IL-1ra	Indirect	Genus	serum_cytokines	0.0114	0.0288	no	up	no	no	up	up	HC
Alistipes	IL-1ra	Alistipes+Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.0114	0.0288	no	up	no	no	up	up	HC
Butyricimonas	IL-1ra	Butyricimonas+16:0/20:3-PC+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.17	0.0288	no	no	no	no	up	up	HC
Butyricimonas	IL-1ra	Butyricimonas+L-Tyrosine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.17	0.0288	no	no	no	no	up	up	HC
Butyricimonas	IL-1ra	Butyricimonas+Calcium signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.17	0.0288	no	no	no	no	up	up	HC
Butyricimonas	IL-1ra	Butyricimonas+L-Phenylalanine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.17	0.0288	no	no	no	no	up	up	HC
Butyricimonas	IL-1ra	Butyricimonas+L-Methionine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.17	0.0288	no	no	no	no	up	up	HC
Butyricimonas	IL-1ra	Butyricimonas+Phospholipase D signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.17	0.0288	no	no	no	no	up	up	HC
Butyricimonas	IL-1ra	Butyricimonas+Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.17	0.0288	no	no	no	no	up	up	HC
Collinsella	IL-1ra	Collinsella-18:1-LPC+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.128	0.0288	no	no	no	no	up	up	HC
iso-DCA+stool	IL-1ra	iso-DCA+stool-L-Tryptophan+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.155	0.0288	no	no	no	no	up	up	HC
iso-DCA+stool	IL-1ra	iso-DCA+stool-nutriCA+stool-L-Homocystine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.155	0.0288	no	no	no	no	up	up	HC
LCA+stool	IL-1ra	LCA+stool-TCA+stool-L-Tryptophan+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	HC
LCA+stool	IL-1ra	"LCA+stool+9,10-EPOME+blood-Betaine+blood-IL-1ra"	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	HC
LCA+stool	IL-1ra	LCA+stool-nutriCA+stool-L-Homocystine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	HC
LCA+stool	IL-1ra	LCA+stool-DMG+blood+L-Arginine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	HC
LCA+stool	IL-1ra	LCA+stool-TCA+stool-Choline+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	HC
LCA+stool	IL-1ra	LCA+stool+16:0/18:2-PC+blood+16:0/20:3-PC+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	HC
LCA+stool	IL-1ra	LCA+stool+16:0/18:1-PC+blood+16:0/20:3-PC+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	HC
LCA+stool	IL-1ra	LCA+stool+16:0/18:2-PC+blood+L-Methionine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	HC
LCA+stool	IL-1ra	LCA+stool+16:0/18:2-PC+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	HC
LCA+stool	IL-1ra	LCA+stool+16:0/18:1-PC+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	HC
LCA+stool	IL-1ra	LCA+stool+18:1/16:0-PC+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	HC
LCA+stool	IL-1ra	LCA+stool+18:0/16:0-PC+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	HC
LCA+stool	IL-1ra	LCA+stool-TCA+stool-iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	HC
LCA+stool	IL-1ra	LCA+stool+18:2-LPA+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	HC
LCA+stool	IL-1ra	LCA+stool+16:0/18:2-PC+blood+L-Phenylalanine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	HC
LCA+stool	IL-1ra	LCA+stool+18:1/16:0-PC+blood+L-Phenylalanine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.314	0.0288	no	no	no	no	up	up	HC
Akkermansia	IL-1ra	Akkermansia+d18:1-22:1-SM+blood-L-Phenylalanine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.23	0.0288	no	no	no	no	up	up	HC
Akkermansia	IL-1ra	Akkermansia-Wnt signaling pathway+Choline+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.23	0.0288	no	no	no	no	up	up	HC
Akkermansia	IL-1ra	Akkermansia-Ribosome+Calcium signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.23	0.0288	no	no	no	no	up	up	HC
Akkermansia	IL-1ra	Akkermansia-Acetic acid+stool-L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.23	0.0288	no	no	no	no	up	up	HC
Akkermansia	IL-1ra	Akkermansia-Wnt signaling pathway-Legionellosis+IL-1ra	Indirect	Genus	serum_cytokines	0.23	0.0288	no	no	no	no	up	up	HC
Akkermansia	IL-1ra	Akkermansia-Acetic acid+stool-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.23	0.0288	no	no	no	no	up	up	HC
Akkermansia	IL-1ra	Akkermansia-Wnt signaling pathway+Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.23	0.0288	no	no	no	no	up	up	HC
Akkermansia	IL-1ra	Akkermansia+Pertussis-Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.23	0.0288	no	no	no	no	up	up	HC
Akkermansia	IL-1ra	Akkermansia-Coronavirus disease - COVID-19+Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.23	0.0288	no	no	no	no	up	up	HC
Akkermansia	IL-1ra	Akkermansia-Ribosome+Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.23	0.0288	no	no	no	no	up	up	HC
Akkermansia	IL-1ra	Akkermansia-Wnt signaling pathway-Primary immunodeficiency+IL-1ra	Indirect	Genus	serum_cytokines	0.23	0.0288	no	no	no	no	up	up	HC
Bifidobacterium	IL-1ra	Bifidobacterium+24:0+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.105	0.0288	no	dn	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-TCA+stool-Choline+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Biosynthesis of amino acids-Choline+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-cGMP-PKG signaling pathway+Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Endocrine resistance+Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-MicroRNAs in cancer+Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Pancreatic cancer+Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Biosynthesis of amino acids-Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-FoxO signaling pathway+Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Ubiquitin mediated proteolysis-Primary immunodeficiency+IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Thermogenesis-Primary immunodeficiency+IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-FoxO signaling pathway+Primary immunodeficiency+IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Peroxisome+Primary immunodeficiency+IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Fc gamma R-mediated phagocytosis+Primary immunodeficiency+IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Pathways of neurodegeneration - multiple diseases-Primary immunodeficiency+IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Thermogenesis+Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Endocrine resistance+Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Amphetamine addiction+Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Dopaminergic synapse+Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Neutrophil extracellular trap formation-Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Coronavirus disease - COVID-19+Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Ribosome+Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Biosynthesis of amino acids-Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Peroxisome-Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Pathways of neurodegeneration - multiple diseases+Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-cGMP-PKG signaling pathway+L-Methionine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Dopaminergic synapse+L-Methionine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Pancreatic cancer+L-Methionine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Biosynthesis of amino acids-L-Methionine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-cGMP-PKG signaling pathway+L-Tyrosine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Biosynthesis of amino acids-L-Tyrosine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Thermogenesis-Legionellosis+IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Endocrine resistance-Legionellosis+IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Amphetamine addiction-Legionellosis+IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Dopaminergic synapse-Legionellosis+IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Biosynthesis of amino acids+Legionellosis+IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Thermogenesis+L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Endocrine resistance+L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-4-hydroxybenzoic acid+stool-L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Dopaminergic synapse+L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Neutrophil extracellular trap formation-L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Biosynthesis of amino acids-L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Fc gamma R-mediated phagocytosis-L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Pathways of neurodegeneration - multiple diseases+L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+18:1/18:1-PC+blood+18:1/20:3-PC+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Endocrine resistance+L-Tryptophan+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-TCA+stool-L-Tryptophan+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+18:1/18:1-PC+blood+iso-DCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-TCA+stool-iso-DCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+18:2-LPA+blood+iso-DCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Endocrine resistance+Calcium signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Ribosome+Calcium signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Biosynthesis of amino acids-Calcium signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Endocrine resistance+L-Phenylalanine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Pancreatic cancer+L-Phenylalanine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-Biosynthesis of amino acids-L-Phenylalanine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus-FoxO signaling pathway+L-Phenylalanine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
Ruminococcus	IL-1ra	Ruminococcus+Endocrine resistance+Phospholipase D signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.335	0.0288	no	no	no	no	up	up	HC
GCDCA+blood	IL-1ra	GCDCA+blood-iso-DCA+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.31	0.0288	no	no	no	no	up	up	HC
[Prevotella]	IL-1ra	[Prevotella]+24:0+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.367	0.0288	no	no	no	no	up	up	HC
ACA+blood	IL-1ra	ACA+blood-d18:1-14:0-SM+blood-L-Methionine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.338	0.0288	no	no	no	no	up	up	HC
DCA+stool	IL-1ra	DCA+stool-20:1-LPA+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	HC
DCA+stool	IL-1ra	DCA+stool-DMG+blood+L-Arginine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	HC
DCA+stool	IL-1ra	DCA+stool-20:1-LPA+blood-L-Homocystine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	HC
DCA+stool	IL-1ra	DCA+stool-8-HETE+blood-L-Homocystine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	HC
DCA+stool	IL-1ra	DCA+stool-L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	HC
DCA+stool	IL-1ra	DCA+stool-L-Tryptophan+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.195	0.0288	no	no	no	no	up	up	HC
Butyric acid+stool	IL-1ra	Butyric acid+stool-d18:1-22:1-SM+blood-L-Phenylalanine+blood-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.102	0.0288	dn	no	no	no	up	up	HC
Butyric acid+stool	IL-1ra	Butyric acid+stool-Indole-3-Acetic acid+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.102	0.0288	dn	no	no	no	up	up	HC
Butyric acid+stool	IL-1ra	Butyric acid+stool-L-Tryptophan+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.102	0.0288	dn	no	no	no	up	up	HC
Butyric acid+stool	IL-1ra	Butyric acid+stool-L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.102	0.0288	dn	no	no	no	up	up	HC
Butyric acid+stool	IL-1ra	Butyric acid+stool+16:0/16:0-PC+blood+iso-DCA+blood-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.102	0.0288	dn	no	no	no	up	up	HC
4-hydroxybenzoic acid+stool	IL-1ra	4-hydroxybenzoic acid+stool-L-Homocystine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.0288	no	dn	no	no	up	up	HC
GCA+blood	IL-1ra	GCA+blood-iso-DCA+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.16	0.0288	no	no	no	no	up	up	HC
ACA+stool	IL-1ra	ACA+stool-18:0/18:2-PI+blood+24:0+blood+IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.417	0.0288	no	no	no	no	up	up	HC
ACA+stool	IL-1ra	ACA+stool-Acetic acid+stool-L-Homocystine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.417	0.0288	no	no	no	no	up	up	HC
ACA+stool	IL-1ra	ACA+stool-Acetic acid+stool-Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.417	0.0288	no	no	no	no	up	up	HC
CDCA+blood	IL-1ra	CDCA+blood-L-2-Aminobutyric acid+blood+L-Tyrosine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.506	0.0288	no	no	no	no	up	up	HC
CDCA+blood	IL-1ra	CDCA+blood-Creatinine+blood+L-Tyrosine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.506	0.0288	no	no	no	no	up	up	HC
CDCA+blood	IL-1ra	CDCA+blood-d18:1-18:0-SM+blood+iso-DCA+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.506	0.0288	no	no	no	no	up	up	HC
CDCA+blood	IL-1ra	CDCA+blood+GUDCA+blood-iso-DCA+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.506	0.0288	no	no	no	no	up	up	HC
CDCA+blood	IL-1ra	CDCA+blood+GCDCA+blood-iso-DCA+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.506	0.0288	no	no	no	no	up	up	HC
CDCA+blood	IL-1ra	CDCA+blood-Creatinine+blood+L-Phenylalanine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.506	0.0288	no	no	no	no	up	up	HC
CDCA+blood	IL-1ra	CDCA+blood-Creatinine+blood+L-Tryptophan+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.506	0.0288	no	no	no	no	up	up	HC
CDCA+blood	IL-1ra	CDCA+blood-L-2-Aminobutyric acid+blood+L-Arginine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.506	0.0288	no	no	no	no	up	up	HC
CDCA+blood	IL-1ra	CDCA+blood-Creatinine+blood+L-Arginine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.506	0.0288	no	no	no	no	up	up	HC
CDCA+blood	IL-1ra	CDCA+blood-L-2-Aminobutyric acid+blood+L-Methionine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.506	0.0288	no	no	no	no	up	up	HC
CDCA+blood	IL-1ra	CDCA+blood-Creatinine+blood+L-Methionine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.506	0.0288	no	no	no	no	up	up	HC
capric acid C6+blood	IL-1ra	capric acid C6+blood-Cystine+blood+L-Arginine+blood-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.433	0.0288	no	no	no	no	up	up	HC
Prevotella	IL-1ra	Prevotella-18:1/20:3-PC+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.287	0.0288	no	no	no	no	up	up	HC
Prevotella	IL-1ra	Prevotella-16:0/20:3-PC+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.287	0.0288	no	no	no	no	up	up	HC
Prevotella	IL-1ra	Prevotella-iso-DCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.287	0.0288	no	no	no	no	up	up	HC
iso-DCA+blood	IL-1ra	iso-DCA+blood-IL-1ra	Direct	serum_bileacids	serum_cytokines	0.38	0.0288	no	no	no	no	up	up	HC
HCA+stool	IL-1ra	HCA+stool-L-Homocystine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.155	0.0288	no	no	no	no	up	up	HC
Roseburia	IL-1ra	Roseburia-L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.495	0.0288	no	no	no	no	up	up	HC
12-ketoDCA+stool	IL-1ra	12-ketoDCA+stool-Cystine+blood+L-Arginine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.505	0.0288	no	no	no	no	up	up	HC
12-ketoDCA+stool	IL-1ra	12-ketoDCA+stool-15-HETE+blood+20:1+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.505	0.0288	no	no	no	no	up	up	HC
GLCA+blood	IL-1ra	GLCA+blood+L-Glutamine+blood+L-Lysine+blood+L-Tryptophan+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.319	0.0288	no	no	no	no	up	up	HC
GLCA+blood	IL-1ra	GLCA+blood+L-Glutamine+blood+L-Lysine+blood+L-Phenylalanine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.319	0.0288	no	no	no	no	up	up	HC
GLCA+blood	IL-1ra	GLCA+blood+L-Glutamine+blood+L-Lysine+blood+L-Tyrosine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.319	0.0288	no	no	no	no	up	up	HC
GLCA+blood	IL-1ra	GLCA+blood+L-Glutamine+blood+L-Lysine+blood+L-Methionine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.319	0.0288	no	no	no	no	up	up	HC
L-Tryptophan+stool	IL-1ra	L-Tryptophan+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.557	0.0288	no	no	no	no	up	up	HC
CA+blood	IL-1ra	CA+blood-isocapric acid iso-C6+blood+L-Tyrosine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.606	0.0288	no	no	no	no	up	up	HC
CA+blood	IL-1ra	CA+blood-L-Isoleucine+blood+L-Phenylalanine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.606	0.0288	no	no	no	no	up	up	HC
CA+blood	IL-1ra	CA+blood-L-Isoleucine+blood+L-Tryptophan+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.606	0.0288	no	no	no	no	up	up	HC
GUDCA+stool	IL-1ra	GUDCA+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.0085	0.0288	no	dn	no	no	up	up	HC
L-Phenylalanine+stool	IL-1ra	L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.398	0.0288	no	no	no	no	up	up	HC
butyric acid C4+blood	IL-1ra	butyric acid C4+blood+Cystine+blood+L-Arginine+blood-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.407	0.0288	no	no	no	no	up	up	HC
butyric acid C4+blood	IL-1ra	butyric acid C4+blood+iso-heptanoic acid C7+blood-L-Tyrosine+blood-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.407	0.0288	no	no	no	no	up	up	HC
butyric acid C4+blood	IL-1ra	butyric acid C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.407	0.0288	no	no	no	no	up	up	HC
butyric acid C4+blood	IL-1ra	butyric acid C4+blood+iso-heptanoic acid C7+blood-L-Phenylalanine+blood-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.407	0.0288	no	no	no	no	up	up	HC
GCA+stool	IL-1ra	GCA+stool-L-Methionine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.0809	0.0288	no	no	no	no	up	up	HC
Coprococcus	IL-1ra	Coprococcus+Primary immunodeficiency+IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	HC
Coprococcus	IL-1ra	Coprococcus-18:1-LPC+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	HC
Coprococcus	IL-1ra	Coprococcus-Betaine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	HC
Coprococcus	IL-1ra	Coprococcus-Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	HC
Coprococcus	IL-1ra	Coprococcus-Choline+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.612	0.0288	no	no	no	no	up	up	HC
Oscillospira	IL-1ra	Oscillospira+L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.62	0.0288	no	no	no	no	up	up	HC
HCA+blood	IL-1ra	HCA+blood-L-2-Aminobutyric acid+blood+L-Tyrosine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.544	0.0288	no	no	no	no	up	up	HC
HCA+blood	IL-1ra	HCA+blood-isocapric acid iso-C6+blood+L-Tyrosine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.544	0.0288	no	no	no	no	up	up	HC
HCA+blood	IL-1ra	HCA+blood-L-2-Aminobutyric acid+blood+L-Arginine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.544	0.0288	no	no	no	no	up	up	HC
HCA+blood	IL-1ra	HCA+blood-L-2-Aminobutyric acid+blood+L-Methionine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.544	0.0288	no	no	no	no	up	up	HC
HCA+blood	IL-1ra	HCA+blood-L-Isoleucine+blood+L-Phenylalanine+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.544	0.0288	no	no	no	no	up	up	HC
HCA+blood	IL-1ra	HCA+blood-L-Isoleucine+blood+L-Tryptophan+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.544	0.0288	no	no	no	no	up	up	HC
iso-LCA+stool	IL-1ra	iso-LCA+stool-16:0/18:3-PC+blood-L-Tryptophan+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.72	0.0288	no	no	no	no	up	up	HC
iso-LCA+stool	IL-1ra	iso-LCA+stool+Isobutyric acid+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.72	0.0288	no	no	no	no	up	up	HC
iso-LCA+stool	IL-1ra	iso-LCA+stool+Isovaleric acid+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.72	0.0288	no	no	no	no	up	up	HC
iso-LCA+stool	IL-1ra	iso-LCA+stool-nutriCA+stool-L-Homocystine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.72	0.0288	no	no	no	no	up	up	HC
2-methyl-butyric acid m-C4+blood	IL-1ra	2-methyl-butyric acid m-C4+blood+20:1+blood-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.262	0.0288	no	no	no	no	up	up	HC
DCA+blood	IL-1ra	DCA+blood+GUDCA+blood-iso-DCA+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.122	0.0288	no	no	no	no	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1ra	3-(3-Hydroxyphenyl)propanoic acid+stool-GCA+blood-iso-DCA+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0288	no	no	no	no	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1ra	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/22:6-PC+blood+L-Phenylalanine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0288	no	no	no	no	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1ra	3-(3-Hydroxyphenyl)propanoic acid+stool+14:0/18:2-PC+blood-Choline+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0288	no	no	no	no	up	up	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1ra	3-(3-Hydroxyphenyl)propanoic acid+stool+14:0/18:2-PC+blood-Betaine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.33	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-LCA+stool-nutriCA+stool-L-Homocystine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-iso-LCA+stool-nutriCA+stool-L-Homocystine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-iso-LCA+stool+Isobutyric acid+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-iso-LCA+stool+Isovaleric acid+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-LCA+stool-TCA+stool-iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-LCA+stool+18:2-LPA+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	"GLCA+stool-LCA+stool+9,10-EPOME+blood-Betaine+blood-IL-1ra"	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+L-Phenylalanine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Phenylalanine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-LCA+stool-DMG+blood+L-Arginine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-LCA+stool-TCA+stool-Choline+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+16:0/20:3-PC+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+16:0/20:3-PC+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood-L-Tryptophan+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-LCA+stool-TCA+stool-L-Tryptophan+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
GLCA+stool	IL-1ra	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Methionine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.617	0.0288	no	no	no	no	up	up	HC
Indole-3-Acetic acid+stool	IL-1ra	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.304	0.0288	no	no	no	no	up	up	HC
TCA+stool	IL-1ra	TCA+stool-L-Tryptophan+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.458	0.0288	no	no	no	no	up	up	HC
TCA+stool	IL-1ra	TCA+stool-iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.458	0.0288	no	no	no	no	up	up	HC
TCA+stool	IL-1ra	TCA+stool-Choline+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.458	0.0288	no	no	no	no	up	up	HC
HDCA+stool	IL-1ra	HDCA+stool-nutriCA+stool-L-Homocystine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.176	0.0288	no	no	no	no	up	up	HC
HDCA+stool	IL-1ra	HDCA+stool+16:0/18:1-PC+blood+16:0/20:3-PC+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.176	0.0288	no	no	no	no	up	up	HC
HDCA+stool	IL-1ra	HDCA+stool+16:0/20:4-PC+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.176	0.0288	no	no	no	no	up	up	HC
HDCA+stool	IL-1ra	HDCA+stool+16:0/18:1-PC+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.176	0.0288	no	no	no	no	up	up	HC
HDCA+stool	IL-1ra	HDCA+stool+18:0/16:0-PC+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.176	0.0288	no	no	no	no	up	up	HC
HDCA+stool	IL-1ra	HDCA+stool+20:3/16:0-PC+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.176	0.0288	no	no	no	no	up	up	HC
HDCA+stool	IL-1ra	HDCA+stool+18:2-LPA+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.176	0.0288	no	no	no	no	up	up	HC
HDCA+stool	IL-1ra	HDCA+stool-16:0/18:3-PC+blood-L-Tryptophan+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.176	0.0288	no	no	no	no	up	up	HC
Lachnospira	IL-1ra	Lachnospira-24:0+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.279	0.0288	no	no	no	no	up	up	HC
Lachnospira	IL-1ra	Lachnospira-18:1-LPC+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.279	0.0288	no	no	no	no	up	up	HC
isobutyric acid C4+blood	IL-1ra	isobutyric acid C4+blood+L-Isoleucine+blood+L-Phenylalanine+blood-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.0151	0.0288	up	up	no	no	up	up	HC
isobutyric acid C4+blood	IL-1ra	isobutyric acid C4+blood+L-Isoleucine+blood+L-Tryptophan+blood-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.0151	0.0288	up	up	no	no	up	up	HC
GCDCA+stool	IL-1ra	GCDCA+stool-L-Tyrosine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.0471	0.0288	no	dn	no	no	up	up	HC
5-Hydroxytryptamine+stool	IL-1ra	5-Hydroxytryptamine+stool+GCA+stool-L-Methionine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0288	dn	dn	no	no	up	up	HC
5-Hydroxytryptamine+stool	IL-1ra	5-Hydroxytryptamine+stool+GCDCA+stool-L-Tyrosine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.0288	dn	dn	no	no	up	up	HC
Odoribacter	IL-1ra	Odoribacter-Phospholipase D signaling pathway-IL-1ra	Indirect	Genus	serum_cytokines	0.798	0.0288	no	no	no	no	up	up	HC
Isobutyric acid+stool	IL-1ra	Isobutyric acid+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.408	0.0288	no	no	no	no	up	up	HC
Kynurenic acid+stool	IL-1ra	Kynurenic acid+stool-nutriCA+stool-L-Homocystine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.037	0.0288	dn	dn	no	no	up	up	HC
Eggerthella	IL-1ra	Eggerthella+Bacteroides-L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.912	0.0288	no	no	no	no	up	up	HC
Anaerotruncus	IL-1ra	Anaerotruncus-Gemmiger-Cysteine+blood+L-Methionine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.904	0.0288	no	no	no	no	up	up	HC
Anaerotruncus	IL-1ra	Anaerotruncus-Gemmiger-Staphylococcus aureus infection-Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.904	0.0288	no	no	no	no	up	up	HC
Anaerotruncus	IL-1ra	Anaerotruncus-Gemmiger-GPC+blood-L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.904	0.0288	no	no	no	no	up	up	HC
Anaerotruncus	IL-1ra	Anaerotruncus-Gemmiger-20:1-LPA+blood-L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.904	0.0288	no	no	no	no	up	up	HC
Anaerotruncus	IL-1ra	Anaerotruncus-Gemmiger-Cysteine+blood+L-Arginine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.904	0.0288	no	no	no	no	up	up	HC
Anaerotruncus	IL-1ra	Anaerotruncus-Gemmiger-Cysteine+blood+iso-DCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.904	0.0288	no	no	no	no	up	up	HC
Anaerotruncus	IL-1ra	Anaerotruncus-Gemmiger-20:1-LPA+blood+iso-DCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.904	0.0288	no	no	no	no	up	up	HC
Anaerotruncus	IL-1ra	Anaerotruncus-Gemmiger-L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.904	0.0288	no	no	no	no	up	up	HC
Anaerotruncus	IL-1ra	Anaerotruncus-Gemmiger-L-Tryptophan+stool+Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.904	0.0288	no	no	no	no	up	up	HC
Anaerotruncus	IL-1ra	Anaerotruncus-Gemmiger-Staphylococcus aureus infection-Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.904	0.0288	no	no	no	no	up	up	HC
Anaerostipes	IL-1ra	Anaerostipes-20:1+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.568	0.0288	no	no	no	no	up	up	HC
Anaerostipes	IL-1ra	Anaerostipes-18:1-LPC+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.568	0.0288	no	no	no	no	up	up	HC
Isovaleric acid+stool	IL-1ra	Isovaleric acid+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_scfa	serum_cytokines	0.343	0.0288	no	no	no	no	up	up	HC
Paraprevotella	IL-1ra	Paraprevotella+Carbon metabolism+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	HC
Paraprevotella	IL-1ra	Paraprevotella+24:0+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	HC
Paraprevotella	IL-1ra	Paraprevotella-L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	HC
Paraprevotella	IL-1ra	Paraprevotella-Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	HC
Paraprevotella	IL-1ra	Paraprevotella+Glycolysis / Gluconeogenesis+IL-1ra	Indirect	Genus	serum_cytokines	0.118	0.0288	no	no	no	no	up	up	HC
¦Ø-MCA+stool	IL-1ra	¦Ø-MCA+stool-Acetic acid+stool-L-Homocystine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.919	0.0288	no	no	no	no	up	up	HC
¦Ø-MCA+stool	IL-1ra	¦Ø-MCA+stool-Acetic acid+stool-Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.919	0.0288	no	no	no	no	up	up	HC
Phenylacetic acid+stool	IL-1ra	Phenylacetic acid+stool-IL-1ra	Direct	stool_cometabolism	serum_cytokines	0.785	0.0288	no	no	no	no	up	up	HC
Gemmiger	IL-1ra	Gemmiger-Cysteine+blood+L-Methionine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	HC
Gemmiger	IL-1ra	Gemmiger-Staphylococcus aureus infection-Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	HC
Gemmiger	IL-1ra	Gemmiger-GPC+blood-L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	HC
Gemmiger	IL-1ra	Gemmiger-20:1-LPA+blood-L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	HC
Gemmiger	IL-1ra	Gemmiger-Cysteine+blood+L-Arginine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	HC
Gemmiger	IL-1ra	Gemmiger-Cysteine+blood+iso-DCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	HC
Gemmiger	IL-1ra	Gemmiger-20:1-LPA+blood+iso-DCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	HC
Gemmiger	IL-1ra	Gemmiger-L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	HC
Gemmiger	IL-1ra	Gemmiger-L-Tryptophan+stool+Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	HC
Gemmiger	IL-1ra	Gemmiger-Staphylococcus aureus infection-Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.595	0.0288	no	no	no	no	up	up	HC
GDCA+stool	IL-1ra	GDCA+stool-L-Isoleucine+blood+L-Tryptophan+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.656	0.0288	no	no	no	no	up	up	HC
GDCA+stool	IL-1ra	GDCA+stool-16:0/18:2-PC+blood+16:0/20:3-PC+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.656	0.0288	no	no	no	no	up	up	HC
GDCA+stool	IL-1ra	GDCA+stool+d18:1-20:0-SM+blood-L-Arginine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.656	0.0288	no	no	no	no	up	up	HC
GDCA+stool	IL-1ra	GDCA+stool+d18:1-16:0-SM+blood-L-Arginine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.656	0.0288	no	no	no	no	up	up	HC
GDCA+stool	IL-1ra	GDCA+stool+d18:0-16:0-SM+blood-L-Arginine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.656	0.0288	no	no	no	no	up	up	HC
GDCA+stool	IL-1ra	GDCA+stool+d18:1-20:0-SM+blood-L-Homocystine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.656	0.0288	no	no	no	no	up	up	HC
GDCA+stool	IL-1ra	GDCA+stool-18:1/16:0-PC+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.656	0.0288	no	no	no	no	up	up	HC
GDCA+stool	IL-1ra	GDCA+stool-16:0/18:2-PC+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.656	0.0288	no	no	no	no	up	up	HC
GDCA+stool	IL-1ra	GDCA+stool+d18:1-20:0-SM+blood-L-Methionine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.656	0.0288	no	no	no	no	up	up	HC
GDCA+stool	IL-1ra	GDCA+stool-16:0/18:2-PC+blood+L-Methionine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.656	0.0288	no	no	no	no	up	up	HC
GDCA+stool	IL-1ra	GDCA+stool-18:1/16:0-PC+blood+L-Phenylalanine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.656	0.0288	no	no	no	no	up	up	HC
GDCA+stool	IL-1ra	GDCA+stool+d18:1-22:1-SM+blood-L-Phenylalanine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.656	0.0288	no	no	no	no	up	up	HC
GDCA+stool	IL-1ra	GDCA+stool-16:0/18:2-PC+blood+L-Phenylalanine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.656	0.0288	no	no	no	no	up	up	HC
GDCA+stool	IL-1ra	GDCA+stool-L-Isoleucine+blood+L-Phenylalanine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.656	0.0288	no	no	no	no	up	up	HC
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool+20:4/18:0-PE+blood-L-Arginine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	HC
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool+18:1/18:1-PE+blood-L-Arginine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	HC
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool-18:3n6+blood-L-Arginine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	HC
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool+18:1/18:1-PE+blood-L-Methionine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	HC
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool+16:0/22:6-PE+blood-L-Methionine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	HC
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool-18:3n6+blood-L-Methionine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	HC
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool+20:1-LPA+blood+iso-DCA+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	HC
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool-12-ketoDCA+blood-iso-DCA+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	HC
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool+20:1-LPA+blood-L-Homocystine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	HC
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool+8-HETE+blood-L-Homocystine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	HC
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool-12-ketoDCA+blood-18:1-LPC+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	HC
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool-18:3n6+blood-L-Tyrosine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	HC
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool-18:3n6+blood-Choline+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	HC
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool-18:3n6+blood-Betaine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	HC
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool-18:3n6+blood-L-Tryptophan+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	HC
L-Tyrosine+stool	IL-1ra	L-Tyrosine+stool-18:3n6+blood-L-Phenylalanine+blood-IL-1ra	Indirect	stool_cometabolism	serum_cytokines	0.44	0.0288	no	no	no	no	up	up	HC
CDCA+stool	IL-1ra	CDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.663	0.0288	no	no	no	no	up	up	HC
CDCA+stool	IL-1ra	CDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.663	0.0288	no	no	no	no	up	up	HC
CDCA+stool	IL-1ra	CDCA+stool+16:0/18:3-PC+blood-L-Tryptophan+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.663	0.0288	no	no	no	no	up	up	HC
CDCA+stool	IL-1ra	CDCA+stool+GCA+stool-L-Methionine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.663	0.0288	no	no	no	no	up	up	HC
CDCA+stool	IL-1ra	CDCA+stool+nutriCA+stool-L-Homocystine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.663	0.0288	no	no	no	no	up	up	HC
CDCA+stool	IL-1ra	CDCA+stool+HCA+stool-L-Homocystine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.663	0.0288	no	no	no	no	up	up	HC
CA+stool	IL-1ra	CA+stool+16:0/18:3-PC+blood-L-Tryptophan+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.827	0.0288	no	no	no	no	up	up	HC
CA+stool	IL-1ra	CA+stool+nutriCA+stool-L-Homocystine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.827	0.0288	no	no	no	no	up	up	HC
CA+stool	IL-1ra	CA+stool+HCA+stool-L-Homocystine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.827	0.0288	no	no	no	no	up	up	HC
CA+stool	IL-1ra	CA+stool-18:1/16:0-PC+blood+iso-DCA+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.827	0.0288	no	no	no	no	up	up	HC
CA+stool	IL-1ra	CA+stool-18:1/16:0-PC+blood+L-Phenylalanine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.827	0.0288	no	no	no	no	up	up	HC
CA+stool	IL-1ra	CA+stool+GCA+stool-L-Methionine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.827	0.0288	no	no	no	no	up	up	HC
HDCA+blood	IL-1ra	HDCA+blood+L-Tryptophan+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.483	0.0288	no	no	no	no	up	up	HC
UDCA+stool	IL-1ra	UDCA+stool+16:0/18:3-PC+blood-L-Tryptophan+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.266	0.0288	no	no	no	no	up	up	HC
nutriCA+stool	IL-1ra	nutriCA+stool-L-Homocystine+blood-IL-1ra	Indirect	stool_bileacids	serum_cytokines	0.481	0.0288	no	no	no	no	up	up	HC
acetic acid C2+blood	IL-1ra	acetic acid C2+blood+L-2-Aminobutyric acid+blood+L-Tyrosine+blood-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.000193	0.0288	up	dn	no	no	up	up	HC
acetic acid C2+blood	IL-1ra	acetic acid C2+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.000193	0.0288	up	dn	no	no	up	up	HC
acetic acid C2+blood	IL-1ra	acetic acid C2+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-IL-1ra	Indirect	serum_scfa	serum_cytokines	0.000193	0.0288	up	dn	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-Adipocytokine signaling pathway-24:0+blood+IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-Toll-like receptor signaling pathway+Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-Chemical carcinogenesis - receptor activation+Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-Chagas disease+Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium+L-Phenylalanine+stool+Phenylacetic acid+stool-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-Adrenergic signaling in cardiomyocytes-Legionellosis+IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-Adrenergic signaling in cardiomyocytes+L-Tyrosine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium+14:0/18:2-PC+blood-Choline+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium+14:0/18:2-PC+blood-Betaine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium+nutriCA+stool-L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-Chemical carcinogenesis - receptor activation+L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-Chagas disease+L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium+GPC+blood-L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-Adrenergic signaling in cardiomyocytes+L-Homocystine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium+18:0/22:6-PC+blood+L-Phenylalanine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-Chemical carcinogenesis - receptor activation+L-Phenylalanine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium+20:5/18:0-PC+blood+L-Phenylalanine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-Adrenergic signaling in cardiomyocytes+L-Phenylalanine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium+d18:1-14:0-SM+blood-L-Methionine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-Adrenergic signaling in cardiomyocytes+L-Methionine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-d18:0-16:0-SM+blood-L-Arginine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-d18:1-16:0-SM+blood-L-Arginine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-d18:0-24:1-SM+blood-L-Arginine+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-Cushing syndrome+Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-Chemical carcinogenesis - receptor activation+Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium+Peroxisome-Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-Adrenergic signaling in cardiomyocytes+Colorectal cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium+Peroxisome+Primary immunodeficiency+IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-Adipocytokine signaling pathway-Primary immunodeficiency+IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
Clostridium	IL-1ra	Clostridium-Adipocytokine signaling pathway+20:1+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.925	0.0288	no	no	no	no	up	up	HC
12-ketoDCA+blood	IL-1ra	12-ketoDCA+blood-iso-DCA+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.517	0.0288	no	no	no	no	up	up	HC
12-ketoDCA+blood	IL-1ra	12-ketoDCA+blood-18:1-LPC+blood-IL-1ra	Indirect	serum_bileacids	serum_cytokines	0.517	0.0288	no	no	no	no	up	up	HC
Butyricicoccus	IL-1ra	Butyricicoccus-Thyroid hormone signaling pathway-Legionellosis+IL-1ra	Indirect	Genus	serum_cytokines	0.852	0.0288	no	no	no	no	up	up	HC
Butyricicoccus	IL-1ra	Butyricicoccus-Salivary secretion-Legionellosis+IL-1ra	Indirect	Genus	serum_cytokines	0.852	0.0288	no	no	no	no	up	up	HC
Butyricicoccus	IL-1ra	Butyricicoccus-18:2/16:0-PC+blood+iso-DCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.852	0.0288	no	no	no	no	up	up	HC
Butyricicoccus	IL-1ra	Butyricicoccus-HDCA+blood+L-Tryptophan+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.852	0.0288	no	no	no	no	up	up	HC
Butyricicoccus	IL-1ra	Butyricicoccus-Focal adhesion-Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.852	0.0288	no	no	no	no	up	up	HC
Butyricicoccus	IL-1ra	Butyricicoccus-Platelet activation-Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.852	0.0288	no	no	no	no	up	up	HC
Wautersiella	IL-1ra	Wautersiella+Butyricicoccus-Thyroid hormone signaling pathway-Legionellosis+IL-1ra	Indirect	Genus	serum_cytokines	0.289	0.0288	no	no	no	no	up	up	HC
Wautersiella	IL-1ra	Wautersiella+Butyricicoccus-Salivary secretion-Legionellosis+IL-1ra	Indirect	Genus	serum_cytokines	0.289	0.0288	no	no	no	no	up	up	HC
Wautersiella	IL-1ra	Wautersiella+Butyricicoccus-18:2/16:0-PC+blood+iso-DCA+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.289	0.0288	no	no	no	no	up	up	HC
Wautersiella	IL-1ra	Wautersiella+Butyricicoccus-HDCA+blood+L-Tryptophan+blood-IL-1ra	Indirect	Genus	serum_cytokines	0.289	0.0288	no	no	no	no	up	up	HC
Wautersiella	IL-1ra	Wautersiella+Butyricicoccus-Focal adhesion-Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.289	0.0288	no	no	no	no	up	up	HC
Wautersiella	IL-1ra	Wautersiella+Butyricicoccus-Platelet activation-Breast cancer-IL-1ra	Indirect	Genus	serum_cytokines	0.289	0.0288	no	no	no	no	up	up	HC
Blautia	Eotaxin	Blautia+Arginine and proline metabolism-Various types of N-glycan biosynthesis+T cell receptor signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Ras signaling pathway+Signaling pathways regulating pluripotency of stem cells+T cell receptor signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Arginine and proline metabolism+RIG-I-like receptor signaling pathway+T cell receptor signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Arginine and proline metabolism-Various types of N-glycan biosynthesis+Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Ras signaling pathway+Neurotrophin signaling pathway+Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Ras signaling pathway+Long-term potentiation+Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Ras signaling pathway+Sphingolipid signaling pathway+Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Ras signaling pathway+Signaling pathways regulating pluripotency of stem cells+Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Peroxisome-Hippo signaling pathway-Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Ras signaling pathway+Circadian rhythm+Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Ras signaling pathway+VEGF signaling pathway+Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Arginine and proline metabolism+cGMP-PKG signaling pathway+Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Arginine and proline metabolism+RIG-I-like receptor signaling pathway+Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+16:0/20:5-PC+blood-18:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Peroxisome+Primary immunodeficiency-L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Chemical carcinogenesis - receptor activation+18:0-LPC+blood-L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Cushing syndrome+18:0-LPC+blood-L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Ras signaling pathway+Oocyte meiosis-L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Peroxisome+Central carbon metabolism in cancer-L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-18:2-LPC+blood-d18:1-14:1-SM+blood-L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-18:1-LPE+blood-24:1+blood+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Peroxisome+Longevity regulating pathway - multiple species-L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Peroxisome-Kaposi sarcoma-associated herpesvirus infection+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Cushing syndrome+Kaposi sarcoma-associated herpesvirus infection+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+16:0/20:5-PC+blood-18:0/18:2-PI+blood-Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Peroxisome+Primary immunodeficiency-Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Peroxisome+AGE-RAGE signaling pathway in diabetic complications+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Chemical carcinogenesis - receptor activation-Graft-versus-host disease+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Chemical carcinogenesis - receptor activation+18:0-LPC+blood-Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Cushing syndrome+18:0-LPC+blood-Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Chemical carcinogenesis - receptor activation-Viral myocarditis+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Chemical carcinogenesis - receptor activation-Autoimmune thyroid disease+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Ras signaling pathway+Oocyte meiosis-Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Chemical carcinogenesis - receptor activation-Allograft rejection+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Chemical carcinogenesis - receptor activation-Rheumatoid arthritis+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Cushing syndrome-Rheumatoid arthritis+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Butyric acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-18:1-LPE+blood-24:1+blood+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Arginine and proline metabolism+Lysosome+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Peroxisome+Primary immunodeficiency-L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-18:2-LPC+blood+HDCA+blood+L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-18:2-LPC+blood-d18:1-14:1-SM+blood-L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Peroxisome+Longevity regulating pathway - multiple species-L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Arginine and proline metabolism+Apoptosis+L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Peroxisome+Primary immunodeficiency-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Peroxisome+Central carbon metabolism in cancer-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-18:2-LPC+blood-d18:1-14:1-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-18:2-LPC+blood-d18:1-14:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-ACA+blood-d18:1-14:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Cushing syndrome-Leishmaniasis-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Peroxisome-Mineral absorption+L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Cushing syndrome+Mineral absorption+L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-18:2-LPC+blood-d18:1-14:1-SM+blood-L-Alanine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Ras signaling pathway-GCA+blood+L-Alanine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Peroxisome+18:0/18:0-PS+blood-L-Alanine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Ras signaling pathway-GCDCA+blood+L-Alanine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	"Blautia+Peroxisome-Circadian entrainment-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	"Blautia-18:2-LPC+blood-d18:1-14:0-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	"Blautia-ACA+blood-d18:1-14:0-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	"Blautia-Cushing syndrome+Salivary secretion-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	"Blautia-Ras signaling pathway+Gastric cancer+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	"Blautia+Arginine and proline metabolism-Gastric cancer+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Ras signaling pathway+Oocyte meiosis-L-Glutamic acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Ras signaling pathway+TGF-beta signaling pathway-L-Glutamic acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Peroxisome-TGF-beta signaling pathway-L-Glutamic acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Arginine and proline metabolism-TGF-beta signaling pathway-L-Glutamic acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Ras signaling pathway+Axon guidance-L-Glutamic acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-18:2-LPC+blood-d18:1-14:1-SM+blood-L-Glutamic acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Ras signaling pathway+Axon guidance-Hematopoietic cell lineage+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Arginine and proline metabolism+Fatty acid metabolism+Hematopoietic cell lineage+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Arginine and proline metabolism+Histidine metabolism+Hematopoietic cell lineage+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+Peroxisome+AGE-RAGE signaling pathway in diabetic complications+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia+16:0/20:5-PC+blood-Choline+blood+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Butyric acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-18:1-LPE+blood-L-Histidine+blood+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-18:2-LPC+blood-d18:1-14:1-SM+blood-L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-CA+blood-L-Isoleucine+blood+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-18:1-LPE+blood-L-Isoleucine+blood+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-Cushing syndrome-Leishmaniasis-L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Blautia	Eotaxin	Blautia-18:1-LPE+blood-Cysteine+blood+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	1.36E-05	0.393	up	dn	dn	no	no	no	HC
Parabacteroides	Eotaxin	Parabacteroides+18:0/22:6-PA+blood-L-Alanine+blood+Eotaxin	Indirect	Genus	serum_cytokines	4.19E-05	0.393	no	up	up	no	no	no	HC
Parabacteroides	Eotaxin	Parabacteroides-9-HODE+blood-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	4.19E-05	0.393	no	up	up	no	no	no	HC
Parabacteroides	Eotaxin	Parabacteroides+Ethanolamine+blood+L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	4.19E-05	0.393	no	up	up	no	no	no	HC
Parabacteroides	Eotaxin	Parabacteroides-9-HODE+blood-L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	4.19E-05	0.393	no	up	up	no	no	no	HC
Parabacteroides	Eotaxin	Parabacteroides+Ethanolamine+blood+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	4.19E-05	0.393	no	up	up	no	no	no	HC
Parabacteroides	Eotaxin	Parabacteroides+Carbon metabolism-Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	4.19E-05	0.393	no	up	up	no	no	no	HC
Parabacteroides	Eotaxin	Parabacteroides+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	4.19E-05	0.393	no	up	up	no	no	no	HC
Parabacteroides	Eotaxin	Parabacteroides+Ethanolamine+blood+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	4.19E-05	0.393	no	up	up	no	no	no	HC
Dorea	Eotaxin	Dorea-VEGF signaling pathway+Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	0.00362	0.393	up	no	dn	no	no	no	HC
Dorea	Eotaxin	Dorea+Legionellosis-L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.00362	0.393	up	no	dn	no	no	no	HC
Dorea	Eotaxin	Dorea-Fc epsilon RI signaling pathway+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.00362	0.393	up	no	dn	no	no	no	HC
Dorea	Eotaxin	Dorea+Legionellosis-Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.00362	0.393	up	no	dn	no	no	no	HC
Dorea	Eotaxin	Dorea-18:0-LPC+blood-Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.00362	0.393	up	no	dn	no	no	no	HC
Dorea	Eotaxin	Dorea-18:0-LPC+blood-L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.00362	0.393	up	no	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium-Staphylococcus aureus infection+Influenza A+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium-Staphylococcus aureus infection+Autoimmune thyroid disease+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium+4-hydroxybenzoic acid+stool+18:0/18:2-PI+blood-Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium-Staphylococcus aureus infection+Viral myocarditis+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium-Staphylococcus aureus infection+Asthma+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium+Butyric acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium-Staphylococcus aureus infection+Allograft rejection+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium-Staphylococcus aureus infection+Rheumatoid arthritis+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium-Staphylococcus aureus infection+Graft-versus-host disease+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium-Staphylococcus aureus infection+Influenza A+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium+Butyric acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium+4-hydroxybenzoic acid+stool+Cysteine+blood+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium-Staphylococcus aureus infection+Influenza A+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium-Staphylococcus aureus infection-Kaposi sarcoma-associated herpesvirus infection+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium+4-hydroxybenzoic acid+stool+18:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium-Staphylococcus aureus infection+Asthma+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium-Staphylococcus aureus infection+Influenza A+L-Glutamic acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
Faecalibacterium	Eotaxin	Faecalibacterium-Staphylococcus aureus infection+Influenza A+L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0039	0.393	no	dn	dn	no	no	no	HC
isocapric acid iso-C6+blood	Eotaxin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.0458	0.393	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Eotaxin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.0458	0.393	no	no	dn	no	no	no	HC
Bacteroides	Eotaxin	"Bacteroides+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	Genus	serum_cytokines	0.000267	0.393	dn	dn	up	no	no	no	HC
Propionic acid+stool	Eotaxin	Propionic acid+stool+16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.0436	0.393	dn	no	up	no	no	no	HC
Propionic acid+stool	Eotaxin	Propionic acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.0436	0.393	dn	no	up	no	no	no	HC
Propionic acid+stool	Eotaxin	Propionic acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.0436	0.393	dn	no	up	no	no	no	HC
[Ruminococcus]	Eotaxin	[Ruminococcus]+9-HODE+blood-L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0679	0.393	no	no	dn	no	no	no	HC
[Ruminococcus]	Eotaxin	[Ruminococcus]+9-HODE+blood-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0679	0.393	no	no	dn	no	no	no	HC
GUDCA+blood	Eotaxin	GUDCA+blood-iso-DCA+blood+L-Histidine+blood+L-Lysine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.0766	0.393	no	no	dn	no	no	no	HC
Acetic acid+stool	Eotaxin	Acetic acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.0656	0.393	dn	no	no	no	no	no	HC
Acetic acid+stool	Eotaxin	Acetic acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.0656	0.393	dn	no	no	no	no	no	HC
Acetic acid+stool	Eotaxin	Acetic acid+stool+16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.0656	0.393	dn	no	no	no	no	no	HC
Alistipes	Eotaxin	Alistipes+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.0114	0.393	no	up	no	no	no	no	HC
Alistipes	Eotaxin	Alistipes-Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	0.0114	0.393	no	up	no	no	no	no	HC
Butyricimonas	Eotaxin	Butyricimonas-Eotaxin	Direct	Genus	serum_cytokines	0.17	0.393	no	no	no	no	no	no	HC
Collinsella	Eotaxin	Collinsella+18:0/18:0-PS+blood-L-Alanine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	HC
Collinsella	Eotaxin	"Collinsella+Glycine, serine and threonine metabolism-Cholinergic synapse-Eotaxin"	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	HC
Collinsella	Eotaxin	"Collinsella+Glycine, serine and threonine metabolism-L-Lysine+blood+Eotaxin"	Indirect	Genus	serum_cytokines	0.128	0.393	no	no	no	no	no	no	HC
iso-DCA+stool	Eotaxin	iso-DCA+stool-L-Tryptophan+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.155	0.393	no	no	no	no	no	no	HC
iso-DCA+stool	Eotaxin	iso-DCA+stool-L-Tryptophan+stool+18:1/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.155	0.393	no	no	no	no	no	no	HC
iso-DCA+stool	Eotaxin	iso-DCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.155	0.393	no	no	no	no	no	no	HC
iso-DCA+stool	Eotaxin	iso-DCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.155	0.393	no	no	no	no	no	no	HC
iso-DCA+stool	Eotaxin	iso-DCA+stool-L-Tryptophan+stool+L-2-Aminobutyric acid+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.155	0.393	no	no	no	no	no	no	HC
iso-DCA+stool	Eotaxin	iso-DCA+stool-L-Tryptophan+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.155	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	"LCA+stool+16:0/18:1-PC+blood-20:3n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	"LCA+stool+18:0/16:0-PC+blood-20:3n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	"LCA+stool+18:0/16:0-PC+blood-TCA+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:1/16:0-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood-16:0/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood-18:1/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:1/16:0-PC+blood-18:1/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:1/16:0-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood-18:0-LPE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:1/16:0-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood+18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood+18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood+18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:1/16:0-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood-18:1/18:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:1/16:0-PC+blood-18:1/18:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood+Creatinine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood+Creatinine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool-TCA+stool-Creatinine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:1/16:0-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood-16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood-18:0-LPE+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:1/16:0-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood+Creatinine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood+Creatinine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool-TCA+stool-Creatinine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood+Glycine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood+Glycine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:1/16:0-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:2-LPA+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool-DMG+blood+L-Arginine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool-DMG+blood+L-Citrulline+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:1/16:0-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood+16:0/20:4-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood+16:0/20:4-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool-TCA+stool+16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood+18:0/22:6-PA+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood+18:0/22:6-PA+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood+18:1/18:0-PS+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood+18:1/18:0-PS+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood+d18:1-20:1-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:2-LPA+blood-DL-methionine sulfoxide+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:1/16:0-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:2-LPA+blood-DL-methionine sulfoxide+blood+L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool-DMG+blood+L-Citrulline+blood+L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:1/16:0-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool-TCA+stool+18:3n6+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:1/16:0-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood+Creatinine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood+Creatinine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool-TCA+stool-Creatinine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool-DMG+blood+L-Arginine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:1/16:0-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool-TCA+stool-Choline+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood+L-Histidine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:1/16:0-PC+blood+L-Histidine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood+Creatinine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood+Creatinine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool-TCA+stool-Creatinine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:2-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+16:0/18:1-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:1/16:0-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
LCA+stool	Eotaxin	LCA+stool+18:0/16:0-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.314	0.393	no	no	no	no	no	no	HC
Akkermansia	Eotaxin	Akkermansia-GLCA+blood+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.23	0.393	no	no	no	no	no	no	HC
Bifidobacterium	Eotaxin	Bifidobacterium-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.105	0.393	no	dn	no	no	no	no	HC
Ruminococcus	Eotaxin	Ruminococcus-Lysosome+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	HC
Ruminococcus	Eotaxin	Ruminococcus-Endocytosis+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	HC
Ruminococcus	Eotaxin	Ruminococcus-FoxO signaling pathway+T cell receptor signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	HC
Ruminococcus	Eotaxin	Ruminococcus-cGMP-PKG signaling pathway+Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	HC
Ruminococcus	Eotaxin	Ruminococcus-FoxO signaling pathway+Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	0.335	0.393	no	no	no	no	no	no	HC
GCDCA+blood	Eotaxin	GCDCA+blood+L-Alanine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.31	0.393	no	no	no	no	no	no	HC
[Prevotella]	Eotaxin	[Prevotella]+Ethanolamine+blood+L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.367	0.393	no	no	no	no	no	no	HC
[Prevotella]	Eotaxin	[Prevotella]+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.367	0.393	no	no	no	no	no	no	HC
[Prevotella]	Eotaxin	[Prevotella]+Ethanolamine+blood+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.367	0.393	no	no	no	no	no	no	HC
[Prevotella]	Eotaxin	[Prevotella]+GLCA+blood+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.367	0.393	no	no	no	no	no	no	HC
[Prevotella]	Eotaxin	[Prevotella]+Ethanolamine+blood+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.367	0.393	no	no	no	no	no	no	HC
ACA+blood	Eotaxin	ACA+blood-d18:1-14:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.338	0.393	no	no	no	no	no	no	HC
ACA+blood	Eotaxin	"ACA+blood-d18:1-14:0-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	serum_bileacids	serum_cytokines	0.338	0.393	no	no	no	no	no	no	HC
DCA+stool	Eotaxin	DCA+stool-DL-methionine sulfoxide+blood+L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.195	0.393	no	no	no	no	no	no	HC
DCA+stool	Eotaxin	DCA+stool-DL-methionine sulfoxide+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.195	0.393	no	no	no	no	no	no	HC
Butyric acid+stool	Eotaxin	Butyric acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.102	0.393	dn	no	no	no	no	no	HC
Butyric acid+stool	Eotaxin	Butyric acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.102	0.393	dn	no	no	no	no	no	HC
4-hydroxybenzoic acid+stool	Eotaxin	4-hydroxybenzoic acid+stool+Cysteine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.393	no	dn	no	no	no	no	HC
4-hydroxybenzoic acid+stool	Eotaxin	4-hydroxybenzoic acid+stool+18:0/18:2-PI+blood-Cystine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.393	no	dn	no	no	no	no	HC
4-hydroxybenzoic acid+stool	Eotaxin	4-hydroxybenzoic acid+stool+18:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.393	no	dn	no	no	no	no	HC
GCA+blood	Eotaxin	GCA+blood+L-Alanine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.16	0.393	no	no	no	no	no	no	HC
ACA+stool	Eotaxin	ACA+stool-18:0/18:2-PI+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.417	0.393	no	no	no	no	no	no	HC
ACA+stool	Eotaxin	ACA+stool-18:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.417	0.393	no	no	no	no	no	no	HC
CDCA+blood	Eotaxin	CDCA+blood-Creatinine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.506	0.393	no	no	no	no	no	no	HC
CDCA+blood	Eotaxin	CDCA+blood+GCDCA+blood+L-Alanine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.506	0.393	no	no	no	no	no	no	HC
CDCA+blood	Eotaxin	CDCA+blood-Creatinine+blood+L-Asparagine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.506	0.393	no	no	no	no	no	no	HC
CDCA+blood	Eotaxin	CDCA+blood-Creatinine+blood+L-Glutamine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.506	0.393	no	no	no	no	no	no	HC
CDCA+blood	Eotaxin	CDCA+blood-L-2-Aminobutyric acid+blood+L-Lysine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.506	0.393	no	no	no	no	no	no	HC
CDCA+blood	Eotaxin	CDCA+blood-Creatinine+blood+L-Lysine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.506	0.393	no	no	no	no	no	no	HC
capric acid C6+blood	Eotaxin	capric acid C6+blood-Cystine+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.433	0.393	no	no	no	no	no	no	HC
Prevotella	Eotaxin	Prevotella-24:1+blood+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.287	0.393	no	no	no	no	no	no	HC
Prevotella	Eotaxin	Prevotella+Estrogen signaling pathway-Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.287	0.393	no	no	no	no	no	no	HC
Prevotella	Eotaxin	Prevotella-Lysosome+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.287	0.393	no	no	no	no	no	no	HC
Prevotella	Eotaxin	Prevotella-24:1+blood+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.287	0.393	no	no	no	no	no	no	HC
Prevotella	Eotaxin	Prevotella+Estrogen signaling pathway-L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.287	0.393	no	no	no	no	no	no	HC
Prevotella	Eotaxin	"Prevotella-18:1/20:3-PC+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	Genus	serum_cytokines	0.287	0.393	no	no	no	no	no	no	HC
Prevotella	Eotaxin	Prevotella+Estrogen signaling pathway-L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.287	0.393	no	no	no	no	no	no	HC
TCA+blood	Eotaxin	"TCA+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	serum_bileacids	serum_cytokines	0.339	0.393	no	no	no	no	no	no	HC
iso-DCA+blood	Eotaxin	iso-DCA+blood+L-Histidine+blood+L-Lysine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.38	0.393	no	no	no	no	no	no	HC
HCA+stool	Eotaxin	HCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.155	0.393	no	no	no	no	no	no	HC
HCA+stool	Eotaxin	HCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.155	0.393	no	no	no	no	no	no	HC
Roseburia	Eotaxin	Roseburia-T cell receptor signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.495	0.393	no	no	no	no	no	no	HC
12-ketoDCA+stool	Eotaxin	12-ketoDCA+stool-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.505	0.393	no	no	no	no	no	no	HC
GLCA+blood	Eotaxin	GLCA+blood+L-Glutamine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.319	0.393	no	no	no	no	no	no	HC
L-Tryptophan+stool	Eotaxin	L-Tryptophan+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.557	0.393	no	no	no	no	no	no	HC
L-Tryptophan+stool	Eotaxin	L-Tryptophan+stool+18:1/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.557	0.393	no	no	no	no	no	no	HC
L-Tryptophan+stool	Eotaxin	L-Tryptophan+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.557	0.393	no	no	no	no	no	no	HC
L-Tryptophan+stool	Eotaxin	L-Tryptophan+stool+L-2-Aminobutyric acid+blood+L-Lysine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.557	0.393	no	no	no	no	no	no	HC
CA+blood	Eotaxin	CA+blood-L-Isoleucine+blood+L-Lysine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.606	0.393	no	no	no	no	no	no	HC
GUDCA+stool	Eotaxin	GUDCA+stool+Phenylacetic acid+stool+d18:1-20:1-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0085	0.393	no	dn	no	no	no	no	HC
GUDCA+stool	Eotaxin	GUDCA+stool+L-Tryptophan+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0085	0.393	no	dn	no	no	no	no	HC
GUDCA+stool	Eotaxin	GUDCA+stool+L-Tryptophan+stool+L-2-Aminobutyric acid+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0085	0.393	no	dn	no	no	no	no	HC
GUDCA+stool	Eotaxin	GUDCA+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0085	0.393	no	dn	no	no	no	no	HC
GUDCA+stool	Eotaxin	GUDCA+stool+L-Tryptophan+stool+18:1/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0085	0.393	no	dn	no	no	no	no	HC
GUDCA+stool	Eotaxin	GUDCA+stool+L-Tryptophan+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0085	0.393	no	dn	no	no	no	no	HC
GUDCA+stool	Eotaxin	GUDCA+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0085	0.393	no	dn	no	no	no	no	HC
GUDCA+stool	Eotaxin	GUDCA+stool+Phenylacetic acid+stool-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0085	0.393	no	dn	no	no	no	no	HC
GUDCA+stool	Eotaxin	GUDCA+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0085	0.393	no	dn	no	no	no	no	HC
GUDCA+stool	Eotaxin	GUDCA+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0085	0.393	no	dn	no	no	no	no	HC
GUDCA+stool	Eotaxin	GUDCA+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0085	0.393	no	dn	no	no	no	no	HC
L-Phenylalanine+stool	Eotaxin	L-Phenylalanine+stool-18:3n6+blood-L-Lysine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.398	0.393	no	no	no	no	no	no	HC
L-Phenylalanine+stool	Eotaxin	L-Phenylalanine+stool+18:1/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.398	0.393	no	no	no	no	no	no	HC
butyric acid C4+blood	Eotaxin	butyric acid C4+blood+Cystine+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.407	0.393	no	no	no	no	no	no	HC
GCA+stool	Eotaxin	GCA+stool+16:0/18:0-PS+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	HC
GCA+stool	Eotaxin	GCA+stool+18:0/22:6-PE+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	HC
GCA+stool	Eotaxin	GCA+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	HC
GCA+stool	Eotaxin	GCA+stool+16:0/18:0-PS+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	HC
GCA+stool	Eotaxin	GCA+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0809	0.393	no	no	no	no	no	no	HC
Coprococcus	Eotaxin	Coprococcus-Influenza A+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	HC
Coprococcus	Eotaxin	Coprococcus-Choline+blood+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	HC
Coprococcus	Eotaxin	Coprococcus-Influenza A+L-Glutamic acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	HC
Coprococcus	Eotaxin	Coprococcus+Primary immunodeficiency-L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	HC
Coprococcus	Eotaxin	Coprococcus+Central carbon metabolism in cancer-L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	HC
Coprococcus	Eotaxin	Coprococcus+16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	HC
Coprococcus	Eotaxin	Coprococcus-Influenza A+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	HC
Coprococcus	Eotaxin	Coprococcus+Primary immunodeficiency-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	HC
Coprococcus	Eotaxin	Coprococcus+Central carbon metabolism in cancer-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	HC
Coprococcus	Eotaxin	Coprococcus+3-(3-Hydroxyphenyl)propanoic acid+stool-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	HC
Coprococcus	Eotaxin	Coprococcus+Ribosome biogenesis in eukaryotes-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	HC
Coprococcus	Eotaxin	Coprococcus+Primary immunodeficiency-L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	HC
Coprococcus	Eotaxin	Coprococcus-Influenza A+L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	HC
Coprococcus	Eotaxin	Coprococcus+Primary immunodeficiency-Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	HC
Coprococcus	Eotaxin	Coprococcus-Lysosome+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	HC
Coprococcus	Eotaxin	Coprococcus+Ribosome biogenesis in eukaryotes-Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	HC
Coprococcus	Eotaxin	Coprococcus-Influenza A+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.612	0.393	no	no	no	no	no	no	HC
Oscillospira	Eotaxin	Oscillospira-9-HODE+blood-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.62	0.393	no	no	no	no	no	no	HC
Oscillospira	Eotaxin	Oscillospira-9-HODE+blood-L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.62	0.393	no	no	no	no	no	no	HC
HCA+blood	Eotaxin	HCA+blood-L-2-Aminobutyric acid+blood+L-Lysine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.544	0.393	no	no	no	no	no	no	HC
HCA+blood	Eotaxin	HCA+blood-L-Isoleucine+blood+L-Lysine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.544	0.393	no	no	no	no	no	no	HC
iso-LCA+stool	Eotaxin	iso-LCA+stool-16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	HC
iso-LCA+stool	Eotaxin	iso-LCA+stool-16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	HC
iso-LCA+stool	Eotaxin	iso-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	HC
iso-LCA+stool	Eotaxin	iso-LCA+stool-16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	HC
iso-LCA+stool	Eotaxin	iso-LCA+stool-16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	HC
iso-LCA+stool	Eotaxin	iso-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.72	0.393	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	Eotaxin	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+L-Asparagine+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.262	0.393	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	Eotaxin	2-methyl-butyric acid m-C4+blood+butyric acid C4+blood+Cystine+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.262	0.393	no	no	no	no	no	no	HC
DCA+blood	Eotaxin	"DCA+blood-n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	serum_bileacids	serum_cytokines	0.122	0.393	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	Eotaxin	3-(3-Hydroxyphenyl)propanoic acid+stool-L-Ornithine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.33	0.393	no	no	no	no	no	no	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	Eotaxin	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Direct	urine_cometabolism	serum_cytokines	0.0125	0.393	up	up	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:2-LPA+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool-TCA+stool+16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Creatinine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Creatinine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool-TCA+stool-Creatinine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Glycine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Glycine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+16:0/20:4-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+16:0/20:4-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool-DMG+blood+L-Citrulline+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool-DMG+blood+L-Arginine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:0-LPE+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-iso-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool-DMG+blood+L-Citrulline+blood+L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:2-LPA+blood-DL-methionine sulfoxide+blood+L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Creatinine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Creatinine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool-TCA+stool-Creatinine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+L-Histidine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Histidine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool-DMG+blood+L-Arginine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool-TCA+stool+18:3n6+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool-TCA+stool-Choline+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Creatinine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Creatinine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool-TCA+stool-Creatinine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-16:0/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-18:1/18:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:1/18:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-18:1/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:1/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:0-LPE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+18:0/22:6-PA+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+18:0/22:6-PA+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+18:1/18:0-PS+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+18:1/18:0-PS+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-iso-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+d18:1-20:1-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:2-LPA+blood-DL-methionine sulfoxide+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Creatinine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Creatinine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool-TCA+stool-Creatinine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	"GLCA+stool-LCA+stool+18:0/16:0-PC+blood-TCA+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	"GLCA+stool-LCA+stool+16:0/18:1-PC+blood-20:3n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
GLCA+stool	Eotaxin	"GLCA+stool-LCA+stool+18:0/16:0-PC+blood-20:3n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	stool_bileacids	serum_cytokines	0.617	0.393	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-18:3n6+blood-L-Lysine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+L-Tryptophan+stool+L-2-Aminobutyric acid+blood+L-Lysine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+L-Tryptophan+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+d18:1-20:1-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Cystine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+18:1/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+L-Tryptophan+stool+18:1/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+L-Tryptophan+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Asparagine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Eotaxin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.304	0.393	no	no	no	no	no	no	HC
TCA+stool	Eotaxin	TCA+stool-Creatinine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	HC
TCA+stool	Eotaxin	TCA+stool+18:3n6+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	HC
TCA+stool	Eotaxin	TCA+stool-Creatinine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	HC
TCA+stool	Eotaxin	TCA+stool-Choline+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	HC
TCA+stool	Eotaxin	TCA+stool-Creatinine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	HC
TCA+stool	Eotaxin	TCA+stool+16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	HC
TCA+stool	Eotaxin	TCA+stool-Creatinine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.458	0.393	no	no	no	no	no	no	HC
HDCA+stool	Eotaxin	HDCA+stool+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	HC
HDCA+stool	Eotaxin	HDCA+stool+Ethanolamine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	HC
HDCA+stool	Eotaxin	HDCA+stool+Ethanolamine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	HC
HDCA+stool	Eotaxin	HDCA+stool+16:0/20:4-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	HC
HDCA+stool	Eotaxin	HDCA+stool+Ethanolamine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	HC
HDCA+stool	Eotaxin	HDCA+stool+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.176	0.393	no	no	no	no	no	no	HC
Lachnospira	Eotaxin	Lachnospira+18:0/22:6-PE+blood-L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.279	0.393	no	no	no	no	no	no	HC
isobutyric acid C4+blood	Eotaxin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.0151	0.393	up	up	no	no	no	no	HC
GCDCA+stool	Eotaxin	GCDCA+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0471	0.393	no	dn	no	no	no	no	HC
GCDCA+stool	Eotaxin	GCDCA+stool-9-HODE+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0471	0.393	no	dn	no	no	no	no	HC
GCDCA+stool	Eotaxin	GCDCA+stool-9-HODE+blood-L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0471	0.393	no	dn	no	no	no	no	HC
GCDCA+stool	Eotaxin	GCDCA+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.0471	0.393	no	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool+GCA+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool+GCDCA+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool-Propionic acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool+GCA+stool+16:0/18:0-PS+blood-Cystine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool+GCA+stool+16:0/18:0-PS+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool+GCA+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool+GCDCA+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool-Propionic acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool+GCDCA+stool-9-HODE+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	Eotaxin	5-Hydroxytryptamine+stool+GCDCA+stool-9-HODE+blood-L-Asparagine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.393	dn	dn	no	no	no	no	HC
Odoribacter	Eotaxin	Odoribacter-18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.798	0.393	no	no	no	no	no	no	HC
Odoribacter	Eotaxin	Odoribacter-Phospholipase D signaling pathway+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.798	0.393	no	no	no	no	no	no	HC
Odoribacter	Eotaxin	Odoribacter-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.798	0.393	no	no	no	no	no	no	HC
Odoribacter	Eotaxin	Odoribacter-Phospholipase D signaling pathway+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.798	0.393	no	no	no	no	no	no	HC
Odoribacter	Eotaxin	Odoribacter-Phospholipase D signaling pathway+L-Glutamic acid+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.798	0.393	no	no	no	no	no	no	HC
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool+Phenylacetic acid+stool+d18:1-20:1-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	HC
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Cystine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	HC
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Asparagine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	HC
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	HC
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	HC
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	HC
Isobutyric acid+stool	Eotaxin	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.408	0.393	no	no	no	no	no	no	HC
Kynurenic acid+stool	Eotaxin	Kynurenic acid+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.037	0.393	dn	dn	no	no	no	no	HC
Kynurenic acid+stool	Eotaxin	Kynurenic acid+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.037	0.393	dn	dn	no	no	no	no	HC
Eggerthella	Eotaxin	"Eggerthella+Bacteroides+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	Genus	serum_cytokines	0.912	0.393	no	no	no	no	no	no	HC
Anaerotruncus	Eotaxin	Anaerotruncus-Gemmiger+GLCA+blood+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.904	0.393	no	no	no	no	no	no	HC
Anaerotruncus	Eotaxin	Anaerotruncus-Gemmiger-Cysteine+blood+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.904	0.393	no	no	no	no	no	no	HC
Anaerostipes	Eotaxin	Anaerostipes-Th1 and Th2 cell differentiation+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.568	0.393	no	no	no	no	no	no	HC
Anaerostipes	Eotaxin	Anaerostipes-Th17 cell differentiation+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.568	0.393	no	no	no	no	no	no	HC
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Cystine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	HC
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Asparagine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	HC
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	HC
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	HC
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	HC
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	HC
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	HC
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	HC
Isovaleric acid+stool	Eotaxin	Isovaleric acid+stool+Phenylacetic acid+stool+d18:1-20:1-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_scfa	serum_cytokines	0.343	0.393	no	no	no	no	no	no	HC
Paraprevotella	Eotaxin	Paraprevotella+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	HC
Paraprevotella	Eotaxin	Paraprevotella+Rheumatoid arthritis+Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	HC
Paraprevotella	Eotaxin	Paraprevotella+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	HC
Paraprevotella	Eotaxin	Paraprevotella+Carbon metabolism-Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	HC
Paraprevotella	Eotaxin	Paraprevotella-Autophagy - animal+Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	HC
Paraprevotella	Eotaxin	Paraprevotella-p53 signaling pathway+Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	HC
Paraprevotella	Eotaxin	Paraprevotella-C-type lectin receptor signaling pathway+Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	HC
Paraprevotella	Eotaxin	Paraprevotella-Autophagy - animal+T cell receptor signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	HC
Paraprevotella	Eotaxin	Paraprevotella-C-type lectin receptor signaling pathway+T cell receptor signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.118	0.393	no	no	no	no	no	no	HC
iso-LCA+blood	Eotaxin	"iso-LCA+blood+L-Proline+blood-MUFA+blood+n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	serum_bileacids	serum_cytokines	0.507	0.393	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Eotaxin	¦Ø-MCA+stool-Propionic acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.919	0.393	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Eotaxin	¦Ø-MCA+stool-Acetic acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.919	0.393	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Eotaxin	¦Ø-MCA+stool-Butyric acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.919	0.393	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Eotaxin	¦Ø-MCA+stool-Propionic acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.919	0.393	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Eotaxin	¦Ø-MCA+stool-Acetic acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.919	0.393	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Eotaxin	¦Ø-MCA+stool-Butyric acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.919	0.393	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Eotaxin	¦Ø-MCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.919	0.393	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Eotaxin	¦Ø-MCA+stool-Acetic acid+stool+16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.919	0.393	no	no	no	no	no	no	HC
Phenylacetic acid+stool	Eotaxin	Phenylacetic acid+stool-14:0/18:2-PC+blood-Cystine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.785	0.393	no	no	no	no	no	no	HC
Phenylacetic acid+stool	Eotaxin	Phenylacetic acid+stool+d18:1-20:1-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.785	0.393	no	no	no	no	no	no	HC
Phenylacetic acid+stool	Eotaxin	Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Asparagine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.785	0.393	no	no	no	no	no	no	HC
Phenylacetic acid+stool	Eotaxin	Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.785	0.393	no	no	no	no	no	no	HC
Phenylacetic acid+stool	Eotaxin	Phenylacetic acid+stool-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.785	0.393	no	no	no	no	no	no	HC
Phenylacetic acid+stool	Eotaxin	Phenylacetic acid+stool-16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.785	0.393	no	no	no	no	no	no	HC
Phenylacetic acid+stool	Eotaxin	Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.785	0.393	no	no	no	no	no	no	HC
Gemmiger	Eotaxin	Gemmiger+GLCA+blood+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	HC
Gemmiger	Eotaxin	Gemmiger-Cysteine+blood+L-Lysine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.595	0.393	no	no	no	no	no	no	HC
GDCA+stool	Eotaxin	GDCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	HC
GDCA+stool	Eotaxin	GDCA+stool-L-Isoleucine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	HC
GDCA+stool	Eotaxin	GDCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.656	0.393	no	no	no	no	no	no	HC
L-Tyrosine+stool	Eotaxin	L-Tyrosine+stool+18:1/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.44	0.393	no	no	no	no	no	no	HC
L-Tyrosine+stool	Eotaxin	L-Tyrosine+stool-18:3n6+blood-L-Lysine+blood+Eotaxin	Indirect	stool_cometabolism	serum_cytokines	0.44	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+HCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+18:3n3+blood-GCDCA+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+18:3n3+blood+DHA+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+18:3n3+blood-GCA+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool-DCA+stool-DL-methionine sulfoxide+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool-HDCA+stool+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+GCA+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool-HDCA+stool+Ethanolamine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+GCA+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+18:3n3+blood+butyric acid C4+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+GCA+stool+16:0/18:0-PS+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	"CDCA+stool+18:3n3+blood+n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+HCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+18:3n3+blood+DHA+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool-DCA+stool-DL-methionine sulfoxide+blood+L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool-HDCA+stool+Ethanolamine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+18:3n3+blood+DHA+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+GCA+stool+16:0/18:0-PS+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool+GCA+stool+18:0/22:6-PE+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool-HDCA+stool+16:0/20:4-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool-HDCA+stool+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CDCA+stool	Eotaxin	CDCA+stool-HDCA+stool+Ethanolamine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.663	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool+GCA+stool+16:0/18:0-PS+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-18:1/16:0-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool+GCA+stool+18:0/22:6-PE+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-HDCA+stool+16:0/20:4-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-HDCA+stool+Ethanolamine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-18:1/16:0-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-HDCA+stool+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-18:1/16:0-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool+GCA+stool+16:0/18:0-PS+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-18:1/16:0-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-18:1/16:0-PC+blood-18:1/18:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-18:1/16:0-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-18:1/16:0-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-18:1/16:0-PC+blood-18:1/18:1-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-18:1/16:0-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-Propionic acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool+GCA+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-18:1/16:0-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-18:1/16:0-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool+GDCA+stool-L-Isoleucine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-Propionic acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool+GCA+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-18:1/16:0-PC+blood+L-Histidine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-HDCA+stool+Ethanolamine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-18:1/16:0-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool+nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool+GDCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool+HCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-18:1/16:0-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-DCA+stool-DL-methionine sulfoxide+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-ACA+blood-d18:1-14:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool+nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool+GDCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool+HCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-DCA+stool-DL-methionine sulfoxide+blood+L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool+16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-HDCA+stool+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-18:1/16:0-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool+16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-HDCA+stool+Ethanolamine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	CA+stool-18:1/16:0-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
CA+stool	Eotaxin	"CA+stool-ACA+blood-d18:1-14:0-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	stool_bileacids	serum_cytokines	0.827	0.393	no	no	no	no	no	no	HC
HDCA+blood	Eotaxin	HDCA+blood+L-Asparagine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.483	0.393	no	no	no	no	no	no	HC
UDCA+stool	Eotaxin	"UDCA+stool+18:3n3+blood+n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	stool_bileacids	serum_cytokines	0.266	0.393	no	no	no	no	no	no	HC
UDCA+stool	Eotaxin	UDCA+stool+16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Glutamic acid+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.266	0.393	no	no	no	no	no	no	HC
UDCA+stool	Eotaxin	UDCA+stool+18:3n3+blood+butyric acid C4+blood+Cystine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.266	0.393	no	no	no	no	no	no	HC
UDCA+stool	Eotaxin	UDCA+stool+18:3n3+blood+DHA+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.266	0.393	no	no	no	no	no	no	HC
UDCA+stool	Eotaxin	UDCA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.266	0.393	no	no	no	no	no	no	HC
UDCA+stool	Eotaxin	UDCA+stool+16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.266	0.393	no	no	no	no	no	no	HC
UDCA+stool	Eotaxin	UDCA+stool+18:3n3+blood+DHA+blood-L-Glutamine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.266	0.393	no	no	no	no	no	no	HC
UDCA+stool	Eotaxin	UDCA+stool+18:3n3+blood+DHA+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.266	0.393	no	no	no	no	no	no	HC
UDCA+stool	Eotaxin	UDCA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.266	0.393	no	no	no	no	no	no	HC
UDCA+stool	Eotaxin	UDCA+stool+18:3n3+blood-GCDCA+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.266	0.393	no	no	no	no	no	no	HC
UDCA+stool	Eotaxin	UDCA+stool+18:3n3+blood-GCA+blood+L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.266	0.393	no	no	no	no	no	no	HC
nutriCA+stool	Eotaxin	nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.481	0.393	no	no	no	no	no	no	HC
nutriCA+stool	Eotaxin	nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	stool_bileacids	serum_cytokines	0.481	0.393	no	no	no	no	no	no	HC
acetic acid C2+blood	Eotaxin	acetic acid C2+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.000193	0.393	up	dn	no	no	no	no	HC
acetic acid C2+blood	Eotaxin	acetic acid C2+blood+heptanoic acid C7+blood+L-Asparagine+blood+Eotaxin	Indirect	serum_scfa	serum_cytokines	0.000193	0.393	up	dn	no	no	no	no	HC
Clostridium	Eotaxin	Clostridium-Toll-like receptor signaling pathway+Cholinergic synapse-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	Clostridium+18:0/20:3-PC+blood-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	Clostridium+14:0/18:2-PC+blood-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	Clostridium+20:2/18:0-PC+blood-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	Clostridium+d18:1-14:0-SM+blood-L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	Clostridium-Adipocytokine signaling pathway+L-Ornithine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	Clostridium+14:0/18:2-PC+blood-Cystine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	Clostridium+14:0/18:2-PC+blood-L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	Clostridium-Adipocytokine signaling pathway+L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	Clostridium+DPA+blood-L-Glutamine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	"Clostridium+TCA+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	"Clostridium+d18:1-14:0-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	Clostridium-Toll-like receptor signaling pathway+T cell receptor signaling pathway-Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	Clostridium+18:0/20:3-PC+blood-L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	Clostridium+14:0/18:2-PC+blood-L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	Clostridium+20:2/18:0-PC+blood-L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	Clostridium+18:0/20:3-PC+blood-L-Alanine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	Clostridium+20:2/18:0-PC+blood-L-Alanine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
Clostridium	Eotaxin	Clostridium-Adipocytokine signaling pathway+L-Alanine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.925	0.393	no	no	no	no	no	no	HC
12-ketoDCA+blood	Eotaxin	12-ketoDCA+blood+16:0/16:1-PI+blood-L-Lysine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.517	0.393	no	no	no	no	no	no	HC
12-ketoDCA+blood	Eotaxin	12-ketoDCA+blood-DPA+blood-L-Glutamine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.517	0.393	no	no	no	no	no	no	HC
12-ketoDCA+blood	Eotaxin	12-ketoDCA+blood+14:0/16:0-PC+blood-L-Asparagine+blood+Eotaxin	Indirect	serum_bileacids	serum_cytokines	0.517	0.393	no	no	no	no	no	no	HC
12-ketoDCA+blood	Eotaxin	"12-ketoDCA+blood-n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	serum_bileacids	serum_cytokines	0.517	0.393	no	no	no	no	no	no	HC
Butyricicoccus	Eotaxin	Butyricicoccus-HDCA+blood+L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.852	0.393	no	no	no	no	no	no	HC
Butyricicoccus	Eotaxin	"Butyricicoccus-Salivary secretion-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	Genus	serum_cytokines	0.852	0.393	no	no	no	no	no	no	HC
Wautersiella	Eotaxin	Wautersiella+Butyricicoccus-HDCA+blood+L-Asparagine+blood+Eotaxin	Indirect	Genus	serum_cytokines	0.289	0.393	no	no	no	no	no	no	HC
Wautersiella	Eotaxin	"Wautersiella+Butyricicoccus-Salivary secretion-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin"	Indirect	Genus	serum_cytokines	0.289	0.393	no	no	no	no	no	no	HC
Blautia	PDGF-bb	Blautia-LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	1.36E-05	0.111	up	dn	dn	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides+Glycolysis / Gluconeogenesis+16:0/16:1-PC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides-Pathways in cancer-16:0/16:1-PC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides+Ethanolamine+blood+LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides+Glycolysis / Gluconeogenesis-cGMP-PKG signaling pathway-PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides+16:0/18:1-PC+blood+18:2-LPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides+16:0/18:1-PC+blood+18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides-RNA degradation-18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides+Biosynthesis of amino acids-iso-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides+Biosynthesis of amino acids-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides-RNA degradation+LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides-mRNA surveillance pathway+LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides-Phosphatidylinositol signaling system+Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides+Biosynthesis of amino acids-Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides-RNA degradation+Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides-Colorectal cancer+Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides+Carbon metabolism-Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides+Glycolysis / Gluconeogenesis-Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides-Pathways in cancer+Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides-mRNA surveillance pathway+Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides+16:0/18:1-PC+blood+16:0/22:6-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Parabacteroides	PDGF-bb	Parabacteroides+18:0/22:6-PA+blood+20:5/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	4.19E-05	0.111	no	up	up	no	no	no	HC
Dorea	PDGF-bb	Dorea-iso-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.00362	0.111	up	no	dn	no	no	no	HC
Dorea	PDGF-bb	Dorea-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.00362	0.111	up	no	dn	no	no	no	HC
Dorea	PDGF-bb	Dorea+16:0/16:1-PC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.00362	0.111	up	no	dn	no	no	no	HC
Faecalibacterium	PDGF-bb	Faecalibacterium+L-Leucine+blood-MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.0039	0.111	no	dn	dn	no	no	no	HC
Faecalibacterium	PDGF-bb	Faecalibacterium+4-hydroxybenzoic acid+stool+HCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.0039	0.111	no	dn	dn	no	no	no	HC
Faecalibacterium	PDGF-bb	Faecalibacterium+Butyric acid+stool-18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.0039	0.111	no	dn	dn	no	no	no	HC
TUDCA+blood	PDGF-bb	TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.0282	0.111	no	no	dn	no	no	no	HC
TUDCA+blood	PDGF-bb	TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.0282	0.111	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	PDGF-bb	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Leucine+blood-MUFA+blood-PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.0458	0.111	no	no	dn	no	no	no	HC
Bacteroides	PDGF-bb	Bacteroides-iso-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.000267	0.111	dn	dn	up	no	no	no	HC
Propionic acid+stool	PDGF-bb	Propionic acid+stool-18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0436	0.111	dn	no	up	no	no	no	HC
[Ruminococcus]	PDGF-bb	[Ruminococcus]-18:0/20:4-PI+blood+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	HC
[Ruminococcus]	PDGF-bb	[Ruminococcus]+Proteasome+HCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	HC
[Ruminococcus]	PDGF-bb	[Ruminococcus]+nutriCA+stool+18:3n3+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	HC
[Ruminococcus]	PDGF-bb	[Ruminococcus]+16:0/18:3-PC+blood+18:3n3+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	HC
[Ruminococcus]	PDGF-bb	"[Ruminococcus]+nutriCA+stool-9,10-EPOME+blood+PDGF-bb"	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	HC
[Ruminococcus]	PDGF-bb	[Ruminococcus]-HDCA+stool+18:2-LPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	HC
[Ruminococcus]	PDGF-bb	[Ruminococcus]-18:0/20:4-PI+blood+18:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	HC
[Ruminococcus]	PDGF-bb	[Ruminococcus]-HDCA+stool+iso-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	HC
[Ruminococcus]	PDGF-bb	[Ruminococcus]-HDCA+stool+LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	HC
[Ruminococcus]	PDGF-bb	[Ruminococcus]-HDCA+stool+LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	HC
[Ruminococcus]	PDGF-bb	[Ruminococcus]+nutriCA+stool-LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	HC
[Ruminococcus]	PDGF-bb	[Ruminococcus]-Hypotaurine+blood+LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0679	0.111	no	no	dn	no	no	no	HC
GUDCA+blood	PDGF-bb	GUDCA+blood-iso-DCA+blood+L-Histidine+blood+L-Isoleucine+blood+L-Leucine+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.0766	0.111	no	no	dn	no	no	no	HC
Acetic acid+stool	PDGF-bb	Acetic acid+stool-18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.0656	0.111	dn	no	no	no	no	no	HC
Alistipes	PDGF-bb	Alistipes+LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.0114	0.111	no	up	no	no	no	no	HC
Alistipes	PDGF-bb	Alistipes-GABAergic synapse-PDGF-bb	Indirect	Genus	serum_cytokines	0.0114	0.111	no	up	no	no	no	no	HC
Alistipes	PDGF-bb	Alistipes-FoxO signaling pathway-PDGF-bb	Indirect	Genus	serum_cytokines	0.0114	0.111	no	up	no	no	no	no	HC
Alistipes	PDGF-bb	Alistipes-cGMP-PKG signaling pathway-PDGF-bb	Indirect	Genus	serum_cytokines	0.0114	0.111	no	up	no	no	no	no	HC
Butyricimonas	PDGF-bb	Butyricimonas+Amoebiasis-PDGF-bb	Indirect	Genus	serum_cytokines	0.17	0.111	no	no	no	no	no	no	HC
Butyricimonas	PDGF-bb	Butyricimonas-16:0/16:1-PC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.17	0.111	no	no	no	no	no	no	HC
Butyricimonas	PDGF-bb	Butyricimonas+20:5/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.17	0.111	no	no	no	no	no	no	HC
Collinsella	PDGF-bb	Collinsella+16:0/16:1-PC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.128	0.111	no	no	no	no	no	no	HC
iso-DCA+stool	PDGF-bb	iso-DCA+stool+iso-LCA+stool+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.155	0.111	no	no	no	no	no	no	HC
iso-DCA+stool	PDGF-bb	iso-DCA+stool+LCA+stool+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.155	0.111	no	no	no	no	no	no	HC
LCA+stool	PDGF-bb	LCA+stool+PDGF-bb	Direct	stool_bileacids	serum_cytokines	0.314	0.111	no	no	no	no	no	no	HC
Akkermansia	PDGF-bb	Akkermansia-LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.23	0.111	no	no	no	no	no	no	HC
Bifidobacterium	PDGF-bb	Bifidobacterium-18:1-LPE+blood-20:5/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	HC
Bifidobacterium	PDGF-bb	Bifidobacterium-12-ketoDCA+blood-18:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	HC
Bifidobacterium	PDGF-bb	Bifidobacterium+13-HODE+blood+18:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	HC
Bifidobacterium	PDGF-bb	Bifidobacterium+13-HODE+blood+18:2-LPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	HC
Bifidobacterium	PDGF-bb	Bifidobacterium-12-ketoDCA+blood+LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	HC
Bifidobacterium	PDGF-bb	Bifidobacterium-CA+blood+LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	HC
Bifidobacterium	PDGF-bb	Bifidobacterium-L-Proline+blood+LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	HC
Bifidobacterium	PDGF-bb	Bifidobacterium-12-ketoDCA+blood-MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	HC
Bifidobacterium	PDGF-bb	Bifidobacterium+AA+blood+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	HC
Bifidobacterium	PDGF-bb	Bifidobacterium-CA+blood-MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	HC
Bifidobacterium	PDGF-bb	Bifidobacterium-L-Proline+blood-MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	HC
Bifidobacterium	PDGF-bb	Bifidobacterium+13-HODE+blood+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	HC
Bifidobacterium	PDGF-bb	Bifidobacterium-12-ketoDCA+blood-18:3n3+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.105	0.111	no	dn	no	no	no	no	HC
Ruminococcus	PDGF-bb	Ruminococcus-cGMP-PKG signaling pathway-PDGF-bb	Indirect	Genus	serum_cytokines	0.335	0.111	no	no	no	no	no	no	HC
Ruminococcus	PDGF-bb	Ruminococcus+LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.335	0.111	no	no	no	no	no	no	HC
Ruminococcus	PDGF-bb	Ruminococcus-GABAergic synapse-PDGF-bb	Indirect	Genus	serum_cytokines	0.335	0.111	no	no	no	no	no	no	HC
Ruminococcus	PDGF-bb	Ruminococcus+18:2-LPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.335	0.111	no	no	no	no	no	no	HC
Ruminococcus	PDGF-bb	Ruminococcus-FoxO signaling pathway-PDGF-bb	Indirect	Genus	serum_cytokines	0.335	0.111	no	no	no	no	no	no	HC
GCDCA+blood	PDGF-bb	GCDCA+blood+HCA+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.31	0.111	no	no	no	no	no	no	HC
[Prevotella]	PDGF-bb	[Prevotella]+LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.367	0.111	no	no	no	no	no	no	HC
[Prevotella]	PDGF-bb	[Prevotella]-18:0/22:6-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.367	0.111	no	no	no	no	no	no	HC
[Prevotella]	PDGF-bb	[Prevotella]-Glutamatergic synapse-PDGF-bb	Indirect	Genus	serum_cytokines	0.367	0.111	no	no	no	no	no	no	HC
ACA+blood	PDGF-bb	ACA+blood+LCA+blood+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.338	0.111	no	no	no	no	no	no	HC
DCA+stool	PDGF-bb	DCA+stool+iso-LCA+stool+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.195	0.111	no	no	no	no	no	no	HC
DCA+stool	PDGF-bb	DCA+stool+LCA+stool+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.195	0.111	no	no	no	no	no	no	HC
2-hydroxyhippuric acid+urine	PDGF-bb	2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8-PDGF-bb	Indirect	urine_cometabolism	serum_cytokines	0.215	0.111	no	no	no	no	no	no	HC
Butyric acid+stool	PDGF-bb	Butyric acid+stool-18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.102	0.111	dn	no	no	no	no	no	HC
4-hydroxybenzoic acid+stool	PDGF-bb	4-hydroxybenzoic acid+stool+HCA+stool-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.111	no	dn	no	no	no	no	HC
GCA+blood	PDGF-bb	GCA+blood+L-Leucine+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.16	0.111	no	no	no	no	no	no	HC
ACA+stool	PDGF-bb	ACA+stool-Acetic acid+stool-18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.417	0.111	no	no	no	no	no	no	HC
CDCA+blood	PDGF-bb	CDCA+blood+HCA+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.506	0.111	no	no	no	no	no	no	HC
capric acid C6+blood	PDGF-bb	capric acid C6+blood-Cystine+blood+L-Glutamine+blood+LCA+blood+PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.433	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella+12-ketoDCA+blood-18:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella+12-ketoDCA+blood+LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella+12-ketoDCA+blood-18:3n3+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-IL-17 signaling pathway+HCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-Lysosome+HCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-IL-17 signaling pathway+GABAergic synapse-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-Lysosome+GABAergic synapse-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-16:1/16:0-PC+blood+20:5/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-20:3/18:0-PC+blood+20:5/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-16:0/20:3-PC+blood+20:5/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella+18:1-LPE+blood-20:5/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-16:0/16:0-PC+blood+20:5/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-16:1/16:1-PC+blood+20:5/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-18:2/20:4-PC+blood+20:5/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-IL-17 signaling pathway-iso-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-Epithelial cell signaling in Helicobacter pylori infection-iso-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Amoebiasis-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-18:0/20:4-PC+blood+18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-16:0/20:3-PC+blood+18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-L-Tryptophan+stool+18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella+12-ketoDCA+blood-MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella+HCA+blood-MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-L-Tryptophan+stool-16:0/16:1-PC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-18:0/20:4-PC+blood+18:2-LPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-16:1/16:0-PC+blood+18:2-LPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-16:0/20:3-PC+blood+18:2-LPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-18:1/18:1-PC+blood+18:2-LPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-16:1/16:1-PC+blood+18:2-LPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
Prevotella	PDGF-bb	Prevotella-16:0/16:0-PC+blood+16:0/22:6-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.287	0.111	no	no	no	no	no	no	HC
TCA+blood	PDGF-bb	TCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.339	0.111	no	no	no	no	no	no	HC
iso-DCA+blood	PDGF-bb	iso-DCA+blood+L-Histidine+blood+L-Isoleucine+blood+L-Leucine+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.38	0.111	no	no	no	no	no	no	HC
HCA+stool	PDGF-bb	HCA+stool-PDGF-bb	Direct	stool_bileacids	serum_cytokines	0.155	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-T cell receptor signaling pathway-Glutamatergic synapse-PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-RNA transport-Glutamatergic synapse-PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-NF-kappa B signaling pathway-Glutamatergic synapse-PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-RNA transport-Amoebiasis-PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-Spliceosome-Amoebiasis-PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-Transcriptional misregulation in cancer+HCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-Transcriptional misregulation in cancer+Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-Hepatitis B+Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-Insulin resistance+Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-Neurotrophin signaling pathway+Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-Transcriptional misregulation in cancer-iso-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-RIG-I-like receptor signaling pathway-iso-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-NF-kappa B signaling pathway-iso-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/22:6-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-Spliceosome-18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-Spliceosome+FoxO signaling pathway-PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-NF-kappa B signaling pathway+FoxO signaling pathway-PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-3-(3-Hydroxyphenyl)propanoic acid+stool-LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-Proteoglycans in cancer+LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-Proteoglycans in cancer-18:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-Proteoglycans in cancer-MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
Roseburia	PDGF-bb	Roseburia-RIG-I-like receptor signaling pathway+GABAergic synapse-PDGF-bb	Indirect	Genus	serum_cytokines	0.495	0.111	no	no	no	no	no	no	HC
12-ketoDCA+stool	PDGF-bb	12-ketoDCA+stool+LCA+stool+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.505	0.111	no	no	no	no	no	no	HC
12-ketoDCA+stool	PDGF-bb	12-ketoDCA+stool+16:0/16:1-PC+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.505	0.111	no	no	no	no	no	no	HC
GLCA+blood	PDGF-bb	GLCA+blood+LCA+blood+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.319	0.111	no	no	no	no	no	no	HC
L-Tryptophan+stool	PDGF-bb	L-Tryptophan+stool+18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.557	0.111	no	no	no	no	no	no	HC
L-Tryptophan+stool	PDGF-bb	L-Tryptophan+stool-16:0/16:1-PC+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.557	0.111	no	no	no	no	no	no	HC
CA+blood	PDGF-bb	CA+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.606	0.111	no	no	no	no	no	no	HC
CA+blood	PDGF-bb	CA+blood+LCA+blood+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.606	0.111	no	no	no	no	no	no	HC
GUDCA+stool	PDGF-bb	GUDCA+stool+L-Tryptophan+stool-16:0/16:1-PC+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0085	0.111	no	dn	no	no	no	no	HC
GUDCA+stool	PDGF-bb	GUDCA+stool+L-Tryptophan+stool+18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0085	0.111	no	dn	no	no	no	no	HC
L-Phenylalanine+stool	PDGF-bb	L-Phenylalanine+stool-16:0/16:1-PC+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.398	0.111	no	no	no	no	no	no	HC
butyric acid C4+blood	PDGF-bb	butyric acid C4+blood+Cystine+blood+L-Glutamine+blood+LCA+blood+PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.407	0.111	no	no	no	no	no	no	HC
butyric acid C4+blood	PDGF-bb	butyric acid C4+blood+isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood-PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.407	0.111	no	no	no	no	no	no	HC
GCA+stool	PDGF-bb	GCA+stool+18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0809	0.111	no	no	no	no	no	no	HC
Coprococcus	PDGF-bb	Coprococcus+3-(3-Hydroxyphenyl)propanoic acid+stool-LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.612	0.111	no	no	no	no	no	no	HC
Coprococcus	PDGF-bb	Coprococcus+3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/22:6-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.612	0.111	no	no	no	no	no	no	HC
Coprococcus	PDGF-bb	Coprococcus+Ribosome biogenesis in eukaryotes-18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.612	0.111	no	no	no	no	no	no	HC
Coprococcus	PDGF-bb	Coprococcus-Influenza A+18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.612	0.111	no	no	no	no	no	no	HC
Coprococcus	PDGF-bb	Coprococcus+Ribosome biogenesis in eukaryotes-Amoebiasis-PDGF-bb	Indirect	Genus	serum_cytokines	0.612	0.111	no	no	no	no	no	no	HC
Coprococcus	PDGF-bb	Coprococcus-Lysosome+HCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.612	0.111	no	no	no	no	no	no	HC
Coprococcus	PDGF-bb	Coprococcus-Lysosome+GABAergic synapse-PDGF-bb	Indirect	Genus	serum_cytokines	0.612	0.111	no	no	no	no	no	no	HC
Oscillospira	PDGF-bb	Oscillospira-HCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	HC
Oscillospira	PDGF-bb	Oscillospira+LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	HC
Oscillospira	PDGF-bb	Oscillospira+iso-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.62	0.111	no	no	no	no	no	no	HC
HCA+blood	PDGF-bb	HCA+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.544	0.111	no	no	no	no	no	no	HC
iso-LCA+stool	PDGF-bb	iso-LCA+stool+PDGF-bb	Direct	stool_bileacids	serum_cytokines	0.72	0.111	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	PDGF-bb	2-methyl-butyric acid m-C4+blood+20:1+blood-22:6n3+blood-LCA+blood+PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.262	0.111	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	PDGF-bb	2-methyl-butyric acid m-C4+blood-22:2-LPA+blood-22:6-LPC+blood-LCA+blood+PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.262	0.111	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	PDGF-bb	2-methyl-butyric acid m-C4+blood+20:1+blood+Glycine+blood+LCA+blood+PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.262	0.111	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	PDGF-bb	2-methyl-butyric acid m-C4+blood+isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood-PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.262	0.111	no	no	no	no	no	no	HC
DCA+blood	PDGF-bb	DCA+blood-isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.122	0.111	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	PDGF-bb	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/22:6-PC+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.33	0.111	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	PDGF-bb	3-(3-Hydroxyphenyl)propanoic acid+stool-LCA+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.33	0.111	no	no	no	no	no	no	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	PDGF-bb	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8-PDGF-bb"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.111	up	up	no	no	no	no	HC
GLCA+stool	PDGF-bb	GLCA+stool-LCA+stool+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.617	0.111	no	no	no	no	no	no	HC
GLCA+stool	PDGF-bb	GLCA+stool-iso-LCA+stool+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.617	0.111	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	PDGF-bb	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-16:0/16:1-PC+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.304	0.111	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	PDGF-bb	Indole-3-Acetic acid+stool+L-Tryptophan+stool-16:0/16:1-PC+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.304	0.111	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	PDGF-bb	Indole-3-Acetic acid+stool+L-Tryptophan+stool+18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.304	0.111	no	no	no	no	no	no	HC
TCA+stool	PDGF-bb	TCA+stool-16:0/18:1-PC+blood+16:0/22:6-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	HC
TCA+stool	PDGF-bb	TCA+stool-16:0/18:2-PC+blood+16:0/22:6-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	HC
TCA+stool	PDGF-bb	TCA+stool-16:0/18:1-PC+blood+18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	HC
TCA+stool	PDGF-bb	TCA+stool-18:0/16:0-PC+blood+18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	HC
TCA+stool	PDGF-bb	TCA+stool-16:0/18:2-PC+blood+18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	HC
TCA+stool	PDGF-bb	TCA+stool-16:0/18:1-PC+blood+18:2-LPA+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	HC
TCA+stool	PDGF-bb	TCA+stool-18:1/18:1-PC+blood+18:2-LPA+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	HC
TCA+stool	PDGF-bb	TCA+stool-18:0/16:0-PC+blood+18:2-LPA+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	HC
TCA+stool	PDGF-bb	TCA+stool-18:2/16:0-PC+blood+20:5/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	HC
TCA+stool	PDGF-bb	TCA+stool-18:0/16:0-PC+blood+20:5/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	HC
TCA+stool	PDGF-bb	TCA+stool-16:0/18:2-PC+blood+20:5/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	HC
TCA+stool	PDGF-bb	TCA+stool-18:1/18:0-PC+blood+20:5/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	HC
TCA+stool	PDGF-bb	TCA+stool-18:1/16:0-PC+blood+20:5/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.458	0.111	no	no	no	no	no	no	HC
HDCA+stool	PDGF-bb	HDCA+stool+LCA+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.176	0.111	no	no	no	no	no	no	HC
HDCA+stool	PDGF-bb	HDCA+stool+iso-LCA+stool+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.176	0.111	no	no	no	no	no	no	HC
HDCA+stool	PDGF-bb	HDCA+stool+LCA+stool+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.176	0.111	no	no	no	no	no	no	HC
HDCA+stool	PDGF-bb	HDCA+stool+18:2-LPA+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.176	0.111	no	no	no	no	no	no	HC
Lachnospira	PDGF-bb	Lachnospira-Proteasome+HCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	HC
Lachnospira	PDGF-bb	Lachnospira-Herpes simplex virus 1 infection+HCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	HC
Lachnospira	PDGF-bb	Lachnospira+GCDCA+stool+18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	HC
Lachnospira	PDGF-bb	Lachnospira+GCA+stool+18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	HC
Lachnospira	PDGF-bb	Lachnospira-13-HODE+blood+18:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	HC
Lachnospira	PDGF-bb	Lachnospira-Inflammatory bowel disease+18:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	HC
Lachnospira	PDGF-bb	Lachnospira-13-HODE+blood+18:2-LPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	HC
Lachnospira	PDGF-bb	Lachnospira+L-Leucine+blood-MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	HC
Lachnospira	PDGF-bb	Lachnospira-13-HODE+blood+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	HC
Lachnospira	PDGF-bb	Lachnospira-Inflammatory bowel disease+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.279	0.111	no	no	no	no	no	no	HC
isobutyric acid C4+blood	PDGF-bb	isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood-PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.0151	0.111	up	up	no	no	no	no	HC
GCDCA+stool	PDGF-bb	GCDCA+stool+18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.0471	0.111	no	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	PDGF-bb	5-Hydroxytryptamine+stool+GCA+stool+18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.111	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	PDGF-bb	5-Hydroxytryptamine+stool+GCDCA+stool+18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.111	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	PDGF-bb	5-Hydroxytryptamine+stool-Propionic acid+stool-18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.111	dn	dn	no	no	no	no	HC
Odoribacter	PDGF-bb	Odoribacter-18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.798	0.111	no	no	no	no	no	no	HC
Isobutyric acid+stool	PDGF-bb	Isobutyric acid+stool+Isovaleric acid+stool-nutriCA+stool+18:3n3+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.408	0.111	no	no	no	no	no	no	HC
Isobutyric acid+stool	PDGF-bb	"Isobutyric acid+stool+Isovaleric acid+stool-nutriCA+stool-9,10-EPOME+blood+PDGF-bb"	Indirect	stool_scfa	serum_cytokines	0.408	0.111	no	no	no	no	no	no	HC
Isobutyric acid+stool	PDGF-bb	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood+18:0/22:6-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.408	0.111	no	no	no	no	no	no	HC
Isobutyric acid+stool	PDGF-bb	Isobutyric acid+stool+Isovaleric acid+stool-nutriCA+stool-LCA+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.408	0.111	no	no	no	no	no	no	HC
Isobutyric acid+stool	PDGF-bb	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-LCA+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.408	0.111	no	no	no	no	no	no	HC
Isobutyric acid+stool	PDGF-bb	Isobutyric acid+stool+Phenylacetic acid+stool-22:6n3+blood-LCA+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.408	0.111	no	no	no	no	no	no	HC
Isobutyric acid+stool	PDGF-bb	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-LCA+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.408	0.111	no	no	no	no	no	no	HC
Isobutyric acid+stool	PDGF-bb	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.408	0.111	no	no	no	no	no	no	HC
Kynurenic acid+stool	PDGF-bb	Kynurenic acid+stool-UDCA+stool+18:3n3+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.037	0.111	dn	dn	no	no	no	no	HC
Kynurenic acid+stool	PDGF-bb	Kynurenic acid+stool-nutriCA+stool+18:3n3+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.037	0.111	dn	dn	no	no	no	no	HC
Kynurenic acid+stool	PDGF-bb	"Kynurenic acid+stool-nutriCA+stool-9,10-EPOME+blood+PDGF-bb"	Indirect	stool_cometabolism	serum_cytokines	0.037	0.111	dn	dn	no	no	no	no	HC
Kynurenic acid+stool	PDGF-bb	Kynurenic acid+stool-nutriCA+stool-LCA+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.037	0.111	dn	dn	no	no	no	no	HC
L-Tryptophan+urine	PDGF-bb	L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8-PDGF-bb	Indirect	urine_cometabolism	serum_cytokines	0.226	0.111	no	no	no	no	no	no	HC
Eggerthella	PDGF-bb	Eggerthella+Bacteroides-iso-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.912	0.111	no	no	no	no	no	no	HC
Eggerthella	PDGF-bb	Eggerthella-Gemmiger+16:0/16:1-PC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.912	0.111	no	no	no	no	no	no	HC
Eggerthella	PDGF-bb	Eggerthella+Clostridium+18:0/22:6-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.912	0.111	no	no	no	no	no	no	HC
Eggerthella	PDGF-bb	Eggerthella+Clostridium+20:5/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.912	0.111	no	no	no	no	no	no	HC
Eggerthella	PDGF-bb	Eggerthella-Gemmiger+LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.912	0.111	no	no	no	no	no	no	HC
Eggerthella	PDGF-bb	Eggerthella+Clostridium-LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.912	0.111	no	no	no	no	no	no	HC
 Eggerthella	PDGF-bb	Eggerthella+Clostridium-LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	NA	0.111	NA	NA	NA	no	no	no	HC
Eggerthella	PDGF-bb	Eggerthella+Clostridium-LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.912	0.111	no	no	no	no	no	no	HC
 Eggerthella	PDGF-bb	Eggerthella+Clostridium-LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	NA	0.111	NA	NA	NA	no	no	no	HC
Anaerotruncus	PDGF-bb	Anaerotruncus-Gemmiger+LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.904	0.111	no	no	no	no	no	no	HC
Anaerotruncus	PDGF-bb	Anaerotruncus-Gemmiger+16:0/16:1-PC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.904	0.111	no	no	no	no	no	no	HC
Anaerostipes	PDGF-bb	Anaerostipes+12-ketoDCA+blood+LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	HC
Anaerostipes	PDGF-bb	Anaerostipes+12-ketoDCA+blood-MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	HC
Anaerostipes	PDGF-bb	Anaerostipes-Inflammatory bowel disease+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	HC
Anaerostipes	PDGF-bb	Anaerostipes+12-ketoDCA+blood-18:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	HC
Anaerostipes	PDGF-bb	Anaerostipes-Inflammatory bowel disease+18:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	HC
Anaerostipes	PDGF-bb	Anaerostipes+Human T-cell leukemia virus 1 infection+HCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	HC
Anaerostipes	PDGF-bb	Anaerostipes+12-ketoDCA+blood-18:3n3+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.568	0.111	no	no	no	no	no	no	HC
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool-nutriCA+stool+18:3n3+blood-PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	HC
Isovaleric acid+stool	PDGF-bb	"Isovaleric acid+stool-nutriCA+stool-9,10-EPOME+blood+PDGF-bb"	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	HC
Isovaleric acid+stool	PDGF-bb	Isovaleric acid+stool-nutriCA+stool-LCA+blood+PDGF-bb	Indirect	stool_scfa	serum_cytokines	0.343	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella-Longevity regulating pathway+Glutamatergic synapse-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella+Rheumatoid arthritis+16:0/16:1-PC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella+Glycolysis / Gluconeogenesis+16:0/16:1-PC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella+Glycolysis / Gluconeogenesis-cGMP-PKG signaling pathway-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella+13-HODE+blood+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella+AA+blood+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella-Insulin resistance+Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella+Carbon metabolism-Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella-Autophagy - animal+Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	"Paraprevotella-Growth hormone synthesis, secretion and action+Glioma-PDGF-bb"	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella-GnRH signaling pathway+Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella-p53 signaling pathway+Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella-C-type lectin receptor signaling pathway+Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella+Glycolysis / Gluconeogenesis-Glioma-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella-18:1-LPE+blood-20:5/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella+13-HODE+blood+18:2-LPA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella+13-HODE+blood+18:1+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella-Autophagy - animal+GABAergic synapse-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	"Paraprevotella-Growth hormone synthesis, secretion and action-HCA+stool-PDGF-bb"	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella+Salmonella infection+HCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella-Chemical carcinogenesis - receptor activation-HCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella-GnRH signaling pathway+18:0/22:6-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella-p53 signaling pathway-18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella-Longevity regulating pathway-18:3n3+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Paraprevotella	PDGF-bb	Paraprevotella+Salmonella infection+18:3n3+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.118	0.111	no	no	no	no	no	no	HC
Homovanillic acid+urine	PDGF-bb	Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8-PDGF-bb	Indirect	urine_cometabolism	serum_cytokines	0.45	0.111	no	no	no	no	no	no	HC
Homovanillic acid+urine	PDGF-bb	Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8-PDGF-bb	Indirect	urine_cometabolism	serum_cytokines	0.45	0.111	no	no	no	no	no	no	HC
TDCA+blood	PDGF-bb	TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.155	0.111	no	up	no	no	no	no	HC
iso-LCA+blood	PDGF-bb	iso-LCA+blood+LCA+blood+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.507	0.111	no	no	no	no	no	no	HC
¦Ø-MCA+stool	PDGF-bb	¦Ø-MCA+stool-LCA+stool+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.919	0.111	no	no	no	no	no	no	HC
Phenylacetic acid+stool	PDGF-bb	Phenylacetic acid+stool-14:0/18:2-PC+blood+18:0/22:6-PC+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.785	0.111	no	no	no	no	no	no	HC
Phenylacetic acid+stool	PDGF-bb	Phenylacetic acid+stool-14:0/18:2-PC+blood-LCA+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.785	0.111	no	no	no	no	no	no	HC
Phenylacetic acid+stool	PDGF-bb	Phenylacetic acid+stool-22:6n3+blood-LCA+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.785	0.111	no	no	no	no	no	no	HC
Phenylacetic acid+stool	PDGF-bb	Phenylacetic acid+stool-16:0/18:2-PI+blood-LCA+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.785	0.111	no	no	no	no	no	no	HC
Phenylacetic acid+stool	PDGF-bb	Phenylacetic acid+stool-16:0/18:2-PI+blood-18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.785	0.111	no	no	no	no	no	no	HC
Gemmiger	PDGF-bb	Gemmiger+LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	HC
Gemmiger	PDGF-bb	Gemmiger+16:0/16:1-PC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.595	0.111	no	no	no	no	no	no	HC
GDCA+stool	PDGF-bb	GDCA+stool-16:0/18:2-PC+blood+16:0/22:6-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.656	0.111	no	no	no	no	no	no	HC
GDCA+stool	PDGF-bb	GDCA+stool-16:0/18:2-PC+blood+18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.656	0.111	no	no	no	no	no	no	HC
GDCA+stool	PDGF-bb	GDCA+stool-Propionic acid+stool-18:0/20:5-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.656	0.111	no	no	no	no	no	no	HC
GDCA+stool	PDGF-bb	GDCA+stool-18:1/16:0-PC+blood+20:5/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.656	0.111	no	no	no	no	no	no	HC
GDCA+stool	PDGF-bb	GDCA+stool-16:0/18:2-PC+blood+20:5/18:0-PC+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.656	0.111	no	no	no	no	no	no	HC
L-Tyrosine+stool	PDGF-bb	L-Tyrosine+stool-16:0/16:1-PC+blood+PDGF-bb	Indirect	stool_cometabolism	serum_cytokines	0.44	0.111	no	no	no	no	no	no	HC
CDCA+stool	PDGF-bb	CDCA+stool-iso-LCA+stool+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.663	0.111	no	no	no	no	no	no	HC
CDCA+stool	PDGF-bb	CDCA+stool-LCA+stool+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.663	0.111	no	no	no	no	no	no	HC
CDCA+stool	PDGF-bb	CDCA+stool+18:3n3+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.663	0.111	no	no	no	no	no	no	HC
CDCA+stool	PDGF-bb	CDCA+stool+HCA+stool-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.663	0.111	no	no	no	no	no	no	HC
CDCA+stool	PDGF-bb	CDCA+stool-LCA+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.663	0.111	no	no	no	no	no	no	HC
CA+stool	PDGF-bb	CA+stool+HCA+stool-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	HC
CA+stool	PDGF-bb	CA+stool-LCA+stool+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	HC
CA+stool	PDGF-bb	CA+stool-LCA+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	HC
CA+stool	PDGF-bb	CA+stool-iso-LCA+stool+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.827	0.111	no	no	no	no	no	no	HC
HDCA+blood	PDGF-bb	HDCA+blood+L-Asparagine+blood+L-Glutamine+blood+LCA+blood+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.483	0.111	no	no	no	no	no	no	HC
HDCA+blood	PDGF-bb	HDCA+blood+L-Aspartic acid+blood+L-Glutamine+blood+LCA+blood+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.483	0.111	no	no	no	no	no	no	HC
UDCA+stool	PDGF-bb	UDCA+stool+18:3n3+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.266	0.111	no	no	no	no	no	no	HC
LCA+blood	PDGF-bb	LCA+blood+PDGF-bb	Direct	serum_bileacids	serum_cytokines	0.884	0.111	no	no	no	no	no	no	HC
nutriCA+stool	PDGF-bb	nutriCA+stool+18:3n3+blood-PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.481	0.111	no	no	no	no	no	no	HC
nutriCA+stool	PDGF-bb	"nutriCA+stool-9,10-EPOME+blood+PDGF-bb"	Indirect	stool_bileacids	serum_cytokines	0.481	0.111	no	no	no	no	no	no	HC
nutriCA+stool	PDGF-bb	nutriCA+stool-LCA+blood+PDGF-bb	Indirect	stool_bileacids	serum_cytokines	0.481	0.111	no	no	no	no	no	no	HC
GDCA+blood	PDGF-bb	GDCA+blood+TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.632	0.111	no	no	no	no	no	no	HC
P-hydroxyhippuric acid+urine	PDGF-bb	P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8-PDGF-bb	Indirect	urine_cometabolism	serum_cytokines	0.436	0.111	no	no	no	no	no	no	HC
acetic acid C2+blood	PDGF-bb	acetic acid C2+blood-LCA+blood+PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.000193	0.111	up	dn	no	no	no	no	HC
isovaleric acid iso-C5+blood	PDGF-bb	isovaleric acid iso-C5+blood+Sarcosine+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8-PDGF-bb	Indirect	serum_scfa	serum_cytokines	0.117	0.111	no	no	no	no	no	no	HC
L-Phenylalanine+urine	PDGF-bb	L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8-PDGF-bb	Indirect	urine_cometabolism	serum_cytokines	0.0908	0.111	no	up	no	no	no	no	HC
Clostridium	PDGF-bb	Clostridium-LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.925	0.111	no	no	no	no	no	no	HC
 Clostridium	PDGF-bb	Clostridium-LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	NA	0.111	NA	NA	NA	no	no	no	HC
Clostridium	PDGF-bb	Clostridium-LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.925	0.111	no	no	no	no	no	no	HC
 Clostridium	PDGF-bb	Clostridium-LCA+blood+PDGF-bb	Indirect	Genus	serum_cytokines	NA	0.111	NA	NA	NA	no	no	no	HC
Clostridium	PDGF-bb	Clostridium+18:0/22:6-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.925	0.111	no	no	no	no	no	no	HC
Clostridium	PDGF-bb	Clostridium+20:5/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.925	0.111	no	no	no	no	no	no	HC
12-ketoDCA+blood	PDGF-bb	12-ketoDCA+blood+LCA+blood+PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.517	0.111	no	no	no	no	no	no	HC
12-ketoDCA+blood	PDGF-bb	12-ketoDCA+blood-18:1+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.517	0.111	no	no	no	no	no	no	HC
12-ketoDCA+blood	PDGF-bb	12-ketoDCA+blood-18:3n3+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.517	0.111	no	no	no	no	no	no	HC
12-ketoDCA+blood	PDGF-bb	12-ketoDCA+blood-MUFA+blood-PDGF-bb	Indirect	serum_bileacids	serum_cytokines	0.517	0.111	no	no	no	no	no	no	HC
Butyricicoccus	PDGF-bb	Butyricicoccus-Thyroid hormone signaling pathway+18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.852	0.111	no	no	no	no	no	no	HC
Butyricicoccus	PDGF-bb	Butyricicoccus-Hepatocellular carcinoma+18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.852	0.111	no	no	no	no	no	no	HC
Butyricicoccus	PDGF-bb	Butyricicoccus-Rap1 signaling pathway+18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.852	0.111	no	no	no	no	no	no	HC
Butyricicoccus	PDGF-bb	Butyricicoccus-Leukocyte transendothelial migration+18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.852	0.111	no	no	no	no	no	no	HC
Butyricicoccus	PDGF-bb	Butyricicoccus-18:2/16:0-PC+blood+20:5/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.852	0.111	no	no	no	no	no	no	HC
Butyricicoccus	PDGF-bb	Butyricicoccus-Thyroid hormone signaling pathway-HCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.852	0.111	no	no	no	no	no	no	HC
Butyricicoccus	PDGF-bb	Butyricicoccus-18:2n6c+blood+18:3n3+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.852	0.111	no	no	no	no	no	no	HC
Butyricicoccus	PDGF-bb	Butyricicoccus-16:0-LPC+blood-16:0/16:1-PC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.852	0.111	no	no	no	no	no	no	HC
Butyricicoccus	PDGF-bb	Butyricicoccus-Thyroid hormone signaling pathway+iso-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.852	0.111	no	no	no	no	no	no	HC
Butyricicoccus	PDGF-bb	Butyricicoccus-Hepatocellular carcinoma+iso-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.852	0.111	no	no	no	no	no	no	HC
Butyricicoccus	PDGF-bb	Butyricicoccus-Platelet activation+iso-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.852	0.111	no	no	no	no	no	no	HC
Butyricicoccus	PDGF-bb	Butyricicoccus-18:2n6c+blood+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.852	0.111	no	no	no	no	no	no	HC
Butyricicoccus	PDGF-bb	Butyricicoccus-Salivary secretion+Amoebiasis-PDGF-bb	Indirect	Genus	serum_cytokines	0.852	0.111	no	no	no	no	no	no	HC
Butyricicoccus	PDGF-bb	Butyricicoccus-Leukocyte transendothelial migration+Amoebiasis-PDGF-bb	Indirect	Genus	serum_cytokines	0.852	0.111	no	no	no	no	no	no	HC
3-Hydroxy-L-kynurenine+urine	PDGF-bb	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8-PDGF-bb	Indirect	urine_cometabolism	serum_cytokines	0.401	0.111	no	no	no	no	no	no	HC
Wautersiella	PDGF-bb	Wautersiella+Butyricicoccus-Thyroid hormone signaling pathway+18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.289	0.111	no	no	no	no	no	no	HC
Wautersiella	PDGF-bb	Wautersiella+Butyricicoccus-Hepatocellular carcinoma+18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.289	0.111	no	no	no	no	no	no	HC
Wautersiella	PDGF-bb	Wautersiella+Butyricicoccus-Rap1 signaling pathway+18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.289	0.111	no	no	no	no	no	no	HC
Wautersiella	PDGF-bb	Wautersiella+Butyricicoccus-Leukocyte transendothelial migration+18:0/20:5-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.289	0.111	no	no	no	no	no	no	HC
Wautersiella	PDGF-bb	Wautersiella+Butyricicoccus-18:2/16:0-PC+blood+20:5/18:0-PC+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.289	0.111	no	no	no	no	no	no	HC
Wautersiella	PDGF-bb	Wautersiella+Butyricicoccus-Thyroid hormone signaling pathway-HCA+stool-PDGF-bb	Indirect	Genus	serum_cytokines	0.289	0.111	no	no	no	no	no	no	HC
Wautersiella	PDGF-bb	Wautersiella+Butyricicoccus-18:2n6c+blood+18:3n3+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.289	0.111	no	no	no	no	no	no	HC
Wautersiella	PDGF-bb	Wautersiella+Butyricicoccus-16:0-LPC+blood-16:0/16:1-PC+blood+PDGF-bb	Indirect	Genus	serum_cytokines	0.289	0.111	no	no	no	no	no	no	HC
Wautersiella	PDGF-bb	Wautersiella+Butyricicoccus-Thyroid hormone signaling pathway+iso-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.289	0.111	no	no	no	no	no	no	HC
Wautersiella	PDGF-bb	Wautersiella+Butyricicoccus-Hepatocellular carcinoma+iso-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.289	0.111	no	no	no	no	no	no	HC
Wautersiella	PDGF-bb	Wautersiella+Butyricicoccus-Platelet activation+iso-LCA+stool+PDGF-bb	Indirect	Genus	serum_cytokines	0.289	0.111	no	no	no	no	no	no	HC
Wautersiella	PDGF-bb	Wautersiella+Butyricicoccus-18:2n6c+blood+MUFA+blood-PDGF-bb	Indirect	Genus	serum_cytokines	0.289	0.111	no	no	no	no	no	no	HC
Wautersiella	PDGF-bb	Wautersiella+Butyricicoccus-Salivary secretion+Amoebiasis-PDGF-bb	Indirect	Genus	serum_cytokines	0.289	0.111	no	no	no	no	no	no	HC
Wautersiella	PDGF-bb	Wautersiella+Butyricicoccus-Leukocyte transendothelial migration+Amoebiasis-PDGF-bb	Indirect	Genus	serum_cytokines	0.289	0.111	no	no	no	no	no	no	HC
Blautia	IL-8	Blautia+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	1.36E-05	0.579	up	dn	dn	no	no	no	HC
Parabacteroides	IL-8	Parabacteroides+Biosynthesis of amino acids-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	HC
Parabacteroides	IL-8	Parabacteroides-RNA degradation+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	HC
Parabacteroides	IL-8	Parabacteroides-mRNA surveillance pathway+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	4.19E-05	0.579	no	up	up	no	no	no	HC
Dorea	IL-8	Dorea-VEGF signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Fc epsilon RI signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-18:2-LPC+blood+20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Endocrine resistance+Huntington disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Endocrine resistance+L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Chemical carcinogenesis - receptor activation+L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	"Dorea-Growth hormone synthesis, secretion and action+L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8"	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Endocrine resistance+mRNA surveillance pathway+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Endocrine resistance+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-GnRH signaling pathway+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Endocrine resistance+Parkinson disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-GnRH signaling pathway+Parkinson disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Endocrine resistance+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Endocrine resistance+RNA degradation+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Endocrine resistance+Thermogenesis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Thyroid hormone signaling pathway+Viral myocarditis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Chemical carcinogenesis - receptor activation-Viral myocarditis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-16:0-LPC+blood+AA+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Amphetamine addiction-Human papillomavirus infection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Amphetamine addiction-Autoimmune thyroid disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Chemical carcinogenesis - receptor activation-Autoimmune thyroid disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-16:0-LPC+blood+TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Amphetamine addiction-Allograft rejection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Chemical carcinogenesis - receptor activation-Allograft rejection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Amphetamine addiction-Graft-versus-host disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Chemical carcinogenesis - receptor activation-Graft-versus-host disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea+Legionellosis-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Amphetamine addiction+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Chemical carcinogenesis - receptor activation+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Amphetamine addiction-Viral carcinogenesis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Endocrine resistance+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-GnRH signaling pathway+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Chemical carcinogenesis - receptor activation-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Dorea	IL-8	Dorea-Endocrine resistance+Alzheimer disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.00362	0.579	up	no	dn	no	no	no	HC
Faecalibacterium	IL-8	Faecalibacterium+Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0039	0.579	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-8	Faecalibacterium-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0039	0.579	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-8	Faecalibacterium-Staphylococcus aureus infection+Viral myocarditis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0039	0.579	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-8	Faecalibacterium-Staphylococcus aureus infection+Allograft rejection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0039	0.579	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-8	Faecalibacterium-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0039	0.579	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-8	Faecalibacterium+4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0039	0.579	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-8	Faecalibacterium-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0039	0.579	no	dn	dn	no	no	no	HC
TUDCA+blood	IL-8	TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.0282	0.579	no	no	dn	no	no	no	HC
TUDCA+blood	IL-8	TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.0282	0.579	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	IL-8	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.0458	0.579	no	no	dn	no	no	no	HC
Bacteroides	IL-8	Bacteroides-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.000267	0.579	dn	dn	up	no	no	no	HC
Propionic acid+stool	IL-8	Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_scfa	serum_cytokines	0.0436	0.579	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-8	Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_scfa	serum_cytokines	0.0436	0.579	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-8	Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_scfa	serum_cytokines	0.0436	0.579	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-8	Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_scfa	serum_cytokines	0.0436	0.579	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-8	Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_scfa	serum_cytokines	0.0436	0.579	dn	no	up	no	no	no	HC
[Ruminococcus]	IL-8	[Ruminococcus]+nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	HC
[Ruminococcus]	IL-8	[Ruminococcus]+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	HC
[Ruminococcus]	IL-8	[Ruminococcus]-Hypotaurine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0679	0.579	no	no	dn	no	no	no	HC
GUDCA+blood	IL-8	GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.0766	0.579	no	no	dn	no	no	no	HC
GUDCA+blood	IL-8	GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.0766	0.579	no	no	dn	no	no	no	HC
GUDCA+blood	IL-8	GUDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.0766	0.579	no	no	dn	no	no	no	HC
GUDCA+blood	IL-8	GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.0766	0.579	no	no	dn	no	no	no	HC
GUDCA+blood	IL-8	GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.0766	0.579	no	no	dn	no	no	no	HC
GUDCA+blood	IL-8	GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.0766	0.579	no	no	dn	no	no	no	HC
GUDCA+blood	IL-8	GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.0766	0.579	no	no	dn	no	no	no	HC
Acetic acid+stool	IL-8	Acetic acid+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_scfa	serum_cytokines	0.0656	0.579	dn	no	no	no	no	no	HC
Alistipes	IL-8	Alistipes+SFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes+20:3/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes+16:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-GDCA+stool-TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-MAPK signaling pathway-Cell adhesion molecules-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Lipid and atherosclerosis+AA+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Progesterone-mediated oocyte maturation-Allograft rejection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-MAPK signaling pathway-Allograft rejection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Peroxisome-Cardiac muscle contraction+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Peroxisome-Alzheimer disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Progesterone-mediated oocyte maturation-Autoimmune thyroid disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-MAPK signaling pathway-Autoimmune thyroid disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Peroxisome-Prion disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Peroxisome-Huntington disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Progesterone-mediated oocyte maturation-Viral myocarditis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Autophagy - animal-Viral myocarditis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-MAPK signaling pathway-Viral myocarditis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Cholinergic synapse-Viral myocarditis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Peroxisome+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Peroxisome-Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Peroxisome-Thermogenesis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-NOD-like receptor signaling pathway-Thermogenesis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Autophagy - animal+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-GABAergic synapse+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-FoxO signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Peroxisome+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Autophagy - animal+L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-GABAergic synapse-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-FoxO signaling pathway-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Peroxisome-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-NOD-like receptor signaling pathway-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Olfactory transduction-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Primary immunodeficiency-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Peroxisome-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Primary immunodeficiency-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-16:0/18:2-PI+blood-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Central carbon metabolism in cancer-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Peroxisome-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Olfactory transduction-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Progesterone-mediated oocyte maturation-Type I diabetes mellitus-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-MAPK signaling pathway-Type I diabetes mellitus-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-GABAergic synapse-Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Peroxisome-Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-NOD-like receptor signaling pathway-Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Progesterone-mediated oocyte maturation-Graft-versus-host disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-MAPK signaling pathway-Graft-versus-host disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-GABAergic synapse-Parkinson disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-Peroxisome-Parkinson disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Alistipes	IL-8	Alistipes-NOD-like receptor signaling pathway-Parkinson disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.0114	0.579	no	up	no	no	no	no	HC
Butyricimonas	IL-8	Butyricimonas+Prion disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.17	0.579	no	no	no	no	no	no	HC
Butyricimonas	IL-8	Butyricimonas+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.17	0.579	no	no	no	no	no	no	HC
Butyricimonas	IL-8	Butyricimonas+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.17	0.579	no	no	no	no	no	no	HC
Collinsella	IL-8	Collinsella-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.128	0.579	no	no	no	no	no	no	HC
iso-DCA+stool	IL-8	iso-DCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.155	0.579	no	no	no	no	no	no	HC
LCA+stool	IL-8	"LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2+IL-8"	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	HC
LCA+stool	IL-8	LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	HC
LCA+stool	IL-8	LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	HC
LCA+stool	IL-8	LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	HC
LCA+stool	IL-8	LCA+stool-TCA+stool-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	HC
LCA+stool	IL-8	LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	HC
LCA+stool	IL-8	LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	HC
LCA+stool	IL-8	LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	HC
LCA+stool	IL-8	LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	HC
LCA+stool	IL-8	LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	HC
LCA+stool	IL-8	LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.314	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia+Systemic lupus erythematosus+Graft-versus-host disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Ribosome-Phagosome-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Ribosome+Cardiac muscle contraction+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Wnt signaling pathway+Retrograde endocannabinoid signaling+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Wnt signaling pathway+Prion disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Ribosome+Prion disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Ribosome-Endocytosis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Wnt signaling pathway+Thermogenesis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Ribosome+Thermogenesis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Wnt signaling pathway+Alzheimer disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Ribosome+Alzheimer disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Ribosome+mRNA surveillance pathway+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Wnt signaling pathway+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Ribosome+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia+Pertussis+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia+Systemic lupus erythematosus+Allograft rejection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Ribosome+RNA degradation+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Acetic acid+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Wnt signaling pathway-Cell adhesion molecules-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Ribosome-Cell adhesion molecules-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Wnt signaling pathway-Human papillomavirus infection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia+Pertussis+Human papillomavirus infection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Ribosome-Human papillomavirus infection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Wnt signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Ribosome+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Wnt signaling pathway-Natural killer cell mediated cytotoxicity-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Ribosome-Natural killer cell mediated cytotoxicity-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Wnt signaling pathway+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Ribosome+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Wnt signaling pathway+Huntington disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Ribosome+Huntington disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Wnt signaling pathway+Parkinson disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Ribosome+Parkinson disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Wnt signaling pathway+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Coronavirus disease - COVID-19+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia-Ribosome+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Akkermansia	IL-8	Akkermansia+Systemic lupus erythematosus-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.23	0.579	no	no	no	no	no	no	HC
Bifidobacterium	IL-8	Bifidobacterium+TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.105	0.579	no	dn	no	no	no	no	HC
Bifidobacterium	IL-8	Bifidobacterium+AA+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.105	0.579	no	dn	no	no	no	no	HC
Ruminococcus	IL-8	Ruminococcus+Thermogenesis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	HC
Ruminococcus	IL-8	Ruminococcus-Endocytosis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	HC
Ruminococcus	IL-8	Ruminococcus-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	HC
Ruminococcus	IL-8	Ruminococcus-Biosynthesis of amino acids-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	HC
Ruminococcus	IL-8	Ruminococcus+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.335	0.579	no	no	no	no	no	no	HC
GCDCA+blood	IL-8	GCDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.31	0.579	no	no	no	no	no	no	HC
GCDCA+blood	IL-8	GCDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.31	0.579	no	no	no	no	no	no	HC
GCDCA+blood	IL-8	GCDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.31	0.579	no	no	no	no	no	no	HC
GCDCA+blood	IL-8	GCDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.31	0.579	no	no	no	no	no	no	HC
GCDCA+blood	IL-8	GCDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.31	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]-18:0/22:6-PC+blood-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]-Glutamatergic synapse-d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]+24:0+blood+AA+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]-Aldosterone synthesis and secretion+Alzheimer disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]-18:0/22:6-PC+blood+TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]-GnRH signaling pathway+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]-Aldosterone synthesis and secretion+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]-Morphine addiction+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	"[Prevotella]-Growth hormone synthesis, secretion and action+L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8"	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]-Aldosterone synthesis and secretion+L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]+24:0+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]-Aldosterone synthesis and secretion+Huntington disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]-Aldosterone synthesis and secretion+Parkinson disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]-GnRH signaling pathway+Parkinson disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]-GnRH signaling pathway+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]-Aldosterone synthesis and secretion+Prion disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
[Prevotella]	IL-8	[Prevotella]+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.367	0.579	no	no	no	no	no	no	HC
ACA+blood	IL-8	ACA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.338	0.579	no	no	no	no	no	no	HC
DCA+stool	IL-8	DCA+stool-8-HETE+blood+TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	HC
DCA+stool	IL-8	DCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	HC
DCA+stool	IL-8	DCA+stool-20:1-LPA+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	HC
DCA+stool	IL-8	DCA+stool-8-HETE+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	HC
DCA+stool	IL-8	DCA+stool-8-HETE+blood+AA+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	HC
DCA+stool	IL-8	DCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	HC
DCA+stool	IL-8	DCA+stool-DL-methionine sulfoxide+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.195	0.579	no	no	no	no	no	no	HC
2-hydroxyhippuric acid+urine	IL-8	2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	urine_cometabolism	serum_cytokines	0.215	0.579	no	no	no	no	no	no	HC
Butyric acid+stool	IL-8	Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_scfa	serum_cytokines	0.102	0.579	dn	no	no	no	no	no	HC
4-hydroxybenzoic acid+stool	IL-8	4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.579	no	dn	no	no	no	no	HC
GCA+blood	IL-8	GCA+blood+TCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.16	0.579	no	no	no	no	no	no	HC
GCA+blood	IL-8	GCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.16	0.579	no	no	no	no	no	no	HC
GCA+blood	IL-8	GCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.16	0.579	no	no	no	no	no	no	HC
GCA+blood	IL-8	GCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.16	0.579	no	no	no	no	no	no	HC
ACA+stool	IL-8	ACA+stool+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.417	0.579	no	no	no	no	no	no	HC
ACA+stool	IL-8	ACA+stool-Acetic acid+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.417	0.579	no	no	no	no	no	no	HC
CDCA+blood	IL-8	CDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.506	0.579	no	no	no	no	no	no	HC
capric acid C6+blood	IL-8	capric acid C6+blood-Cystine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.433	0.579	no	no	no	no	no	no	HC
capric acid C6+blood	IL-8	capric acid C6+blood-Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.433	0.579	no	no	no	no	no	no	HC
capric acid C6+blood	IL-8	capric acid C6+blood-Cystine+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.433	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-Lysosome+Phagosome-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-18:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-16:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-16:0/20:3-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-18:1/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-SFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-16:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-18:1/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella+18:0/18:1-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-24:1+blood-d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella+12-ketoDCA+blood-AA+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-16:1/16:0-PC+blood+AA+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-16:1/16:1-PC+blood+AA+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Human papillomavirus infection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Viral carcinogenesis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella+Estrogen signaling pathway-Viral carcinogenesis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-Lysosome+Viral carcinogenesis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella+18:1-LPE+blood+L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-18:1/18:1-PC+blood+20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella+18:1-LPE+blood-TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella+Estrogen signaling pathway-Autoimmune thyroid disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella+Estrogen signaling pathway-Allograft rejection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella+Estrogen signaling pathway-Graft-versus-host disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella+Estrogen signaling pathway-Type I diabetes mellitus-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella+Estrogen signaling pathway-Viral myocarditis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-16:0/16:0-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-Lysosome+Endocytosis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
Prevotella	IL-8	Prevotella-Lysosome+Natural killer cell mediated cytotoxicity-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.287	0.579	no	no	no	no	no	no	HC
TCA+blood	IL-8	TCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.339	0.579	no	no	no	no	no	no	HC
iso-DCA+blood	IL-8	iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.38	0.579	no	no	no	no	no	no	HC
HCA+stool	IL-8	HCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.155	0.579	no	no	no	no	no	no	HC
Roseburia	IL-8	Roseburia-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.495	0.579	no	no	no	no	no	no	HC
Roseburia	IL-8	Roseburia+TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.495	0.579	no	no	no	no	no	no	HC
12-ketoDCA+stool	IL-8	12-ketoDCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.505	0.579	no	no	no	no	no	no	HC
12-ketoDCA+stool	IL-8	12-ketoDCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.505	0.579	no	no	no	no	no	no	HC
GLCA+blood	IL-8	GLCA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.319	0.579	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-8	L-Tryptophan+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.557	0.579	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-8	L-Tryptophan+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.557	0.579	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-8	L-Tryptophan+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.557	0.579	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-8	L-Tryptophan+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.557	0.579	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-8	L-Tryptophan+stool-12-ketoDCA+blood-AA+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.557	0.579	no	no	no	no	no	no	HC
CA+blood	IL-8	CA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.606	0.579	no	no	no	no	no	no	HC
GUDCA+stool	IL-8	GUDCA+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0085	0.579	no	dn	no	no	no	no	HC
GUDCA+stool	IL-8	GUDCA+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0085	0.579	no	dn	no	no	no	no	HC
L-Phenylalanine+stool	IL-8	L-Phenylalanine+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.398	0.579	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IL-8	L-Phenylalanine+stool-12-ketoDCA+blood-AA+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.398	0.579	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IL-8	L-Phenylalanine+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.398	0.579	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IL-8	L-Phenylalanine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.398	0.579	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IL-8	L-Phenylalanine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.398	0.579	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-8	butyric acid C4+blood+Cystine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.407	0.579	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-8	butyric acid C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.407	0.579	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-8	butyric acid C4+blood+Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.407	0.579	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-8	butyric acid C4+blood+Cystine+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.407	0.579	no	no	no	no	no	no	HC
GCA+stool	IL-8	GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0809	0.579	no	no	no	no	no	no	HC
GCA+stool	IL-8	GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0809	0.579	no	no	no	no	no	no	HC
GCA+stool	IL-8	GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0809	0.579	no	no	no	no	no	no	HC
GCA+stool	IL-8	GCA+stool+18:0/22:6-PE+blood-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0809	0.579	no	no	no	no	no	no	HC
GCA+stool	IL-8	GCA+stool+GDCA+stool-TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0809	0.579	no	no	no	no	no	no	HC
GCA+stool	IL-8	GCA+stool-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0809	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus-18:1/18:2-PG+blood+AA+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus-Lysosome+Viral carcinogenesis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Ribosome biogenesis in eukaryotes-Viral carcinogenesis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus-Influenza A+Viral carcinogenesis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+TCA+stool-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Primary immunodeficiency-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Central carbon metabolism in cancer-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Lachnospira-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus-18:1-LPC+blood+20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus-Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus-18:2-LPC+blood+20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Primary immunodeficiency-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Lachnospira-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus-18:1-LPC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus-Lysosome+Endocytosis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Ribosome biogenesis in eukaryotes-Endocytosis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus-Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Ribosome biogenesis in eukaryotes-Allograft rejection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus-Influenza A+Allograft rejection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Ribosome biogenesis in eukaryotes-Cell adhesion molecules-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Ribosome biogenesis in eukaryotes-Autoimmune thyroid disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus-Influenza A+Autoimmune thyroid disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Ribosome biogenesis in eukaryotes-Cellular senescence-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus-Lysosome+Natural killer cell mediated cytotoxicity-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Ribosome biogenesis in eukaryotes-Natural killer cell mediated cytotoxicity-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Ribosome biogenesis in eukaryotes-Graft-versus-host disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus-Influenza A+Graft-versus-host disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Ribosome biogenesis in eukaryotes-Human papillomavirus infection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus-Influenza A+Human papillomavirus infection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Ribosome biogenesis in eukaryotes+mRNA surveillance pathway+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus-Lysosome+Phagosome-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Ribosome biogenesis in eukaryotes-Phagosome-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Ribosome biogenesis in eukaryotes+RNA degradation+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Ribosome biogenesis in eukaryotes-Type I diabetes mellitus-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus+Ribosome biogenesis in eukaryotes-Viral myocarditis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Coprococcus	IL-8	Coprococcus-Influenza A+Viral myocarditis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.612	0.579	no	no	no	no	no	no	HC
Oscillospira	IL-8	Oscillospira-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	HC
Oscillospira	IL-8	Oscillospira+L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.62	0.579	no	no	no	no	no	no	HC
HCA+blood	IL-8	HCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.544	0.579	no	no	no	no	no	no	HC
iso-LCA+stool	IL-8	iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.72	0.579	no	no	no	no	no	no	HC
iso-LCA+stool	IL-8	iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.72	0.579	no	no	no	no	no	no	HC
iso-LCA+stool	IL-8	iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.72	0.579	no	no	no	no	no	no	HC
iso-LCA+stool	IL-8	iso-LCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.72	0.579	no	no	no	no	no	no	HC
iso-LCA+stool	IL-8	iso-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.72	0.579	no	no	no	no	no	no	HC
iso-LCA+stool	IL-8	iso-LCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.72	0.579	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-8	2-methyl-butyric acid m-C4+blood+20:1+blood-22:6n3+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.262	0.579	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-8	2-methyl-butyric acid m-C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.262	0.579	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-8	2-methyl-butyric acid m-C4+blood+decanoic acid C10+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.262	0.579	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-8	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.262	0.579	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-8	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.262	0.579	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-8	2-methyl-butyric acid m-C4+blood-22:2-LPA+blood-d18:0-24:1-SM+blood+d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.262	0.579	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-8	2-methyl-butyric acid m-C4+blood+20:1+blood+20:1-LPC+blood-TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.262	0.579	no	no	no	no	no	no	HC
DCA+blood	IL-8	DCA+blood+GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.122	0.579	no	no	no	no	no	no	HC
DCA+blood	IL-8	DCA+blood+GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.122	0.579	no	no	no	no	no	no	HC
DCA+blood	IL-8	DCA+blood+GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.122	0.579	no	no	no	no	no	no	HC
DCA+blood	IL-8	DCA+blood+GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.122	0.579	no	no	no	no	no	no	HC
DCA+blood	IL-8	DCA+blood+GUDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.122	0.579	no	no	no	no	no	no	HC
DCA+blood	IL-8	DCA+blood+GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.122	0.579	no	no	no	no	no	no	HC
DCA+blood	IL-8	"DCA+blood-n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8"	Indirect	serum_bileacids	serum_cytokines	0.122	0.579	no	no	no	no	no	no	HC
DCA+blood	IL-8	DCA+blood+GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.122	0.579	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-8	3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.33	0.579	no	no	no	no	no	no	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-8	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.579	up	up	no	no	no	no	HC
GLCA+stool	IL-8	GLCA+stool-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.617	0.579	no	no	no	no	no	no	HC
GLCA+stool	IL-8	GLCA+stool-iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.617	0.579	no	no	no	no	no	no	HC
GLCA+stool	IL-8	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.617	0.579	no	no	no	no	no	no	HC
GLCA+stool	IL-8	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.617	0.579	no	no	no	no	no	no	HC
GLCA+stool	IL-8	GLCA+stool-iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.617	0.579	no	no	no	no	no	no	HC
GLCA+stool	IL-8	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.617	0.579	no	no	no	no	no	no	HC
GLCA+stool	IL-8	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.617	0.579	no	no	no	no	no	no	HC
GLCA+stool	IL-8	GLCA+stool-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.617	0.579	no	no	no	no	no	no	HC
GLCA+stool	IL-8	GLCA+stool-iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.617	0.579	no	no	no	no	no	no	HC
GLCA+stool	IL-8	"GLCA+stool-LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2+IL-8"	Indirect	stool_bileacids	serum_cytokines	0.617	0.579	no	no	no	no	no	no	HC
GLCA+stool	IL-8	GLCA+stool-iso-LCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.617	0.579	no	no	no	no	no	no	HC
GLCA+stool	IL-8	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.617	0.579	no	no	no	no	no	no	HC
GLCA+stool	IL-8	GLCA+stool-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.617	0.579	no	no	no	no	no	no	HC
GLCA+stool	IL-8	GLCA+stool-iso-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.617	0.579	no	no	no	no	no	no	HC
GLCA+stool	IL-8	GLCA+stool-LCA+stool-TCA+stool-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.617	0.579	no	no	no	no	no	no	HC
GLCA+stool	IL-8	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.617	0.579	no	no	no	no	no	no	HC
GLCA+stool	IL-8	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.617	0.579	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-8	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.304	0.579	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-8	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.304	0.579	no	no	no	no	no	no	HC
TCA+stool	IL-8	TCA+stool-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.458	0.579	no	no	no	no	no	no	HC
HDCA+stool	IL-8	HDCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	HC
HDCA+stool	IL-8	HDCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	HC
HDCA+stool	IL-8	HDCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	HC
HDCA+stool	IL-8	HDCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	HC
HDCA+stool	IL-8	HDCA+stool+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	HC
HDCA+stool	IL-8	HDCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	HC
HDCA+stool	IL-8	HDCA+stool+16:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	HC
HDCA+stool	IL-8	HDCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	HC
HDCA+stool	IL-8	HDCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	HC
HDCA+stool	IL-8	HDCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	HC
HDCA+stool	IL-8	HDCA+stool+20:3/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.176	0.579	no	no	no	no	no	no	HC
Lachnospira	IL-8	Lachnospira-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	HC
Lachnospira	IL-8	Lachnospira-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.279	0.579	no	no	no	no	no	no	HC
isobutyric acid C4+blood	IL-8	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.0151	0.579	up	up	no	no	no	no	HC
isobutyric acid C4+blood	IL-8	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.0151	0.579	up	up	no	no	no	no	HC
isobutyric acid C4+blood	IL-8	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.0151	0.579	up	up	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool-9-HODE+blood-L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood+TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood-TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool-Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool-9-HODE+blood+GPC+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood+L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool+18:0/20:5-PC+blood-20:0-LPE+blood+d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool+18:0/20:5-PC+blood+18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool+18:0/20:5-PC+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool+18:0/20:5-PC+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool+18:0/20:5-PC+blood+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool+18:0/20:5-PC+blood+18:1/18:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
GCDCA+stool	IL-8	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.0471	0.579	no	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool+GCA+stool-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool+GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool+GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool+GCA+stool+GDCA+stool-TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-8	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.579	dn	dn	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Endocrine resistance+Huntington disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Long-term depression+Huntington disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Pancreatic secretion+Huntington disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Aldosterone synthesis and secretion+Huntington disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Cushing syndrome+Huntington disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Endocrine resistance+L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Long-term depression+L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Pancreatic secretion+L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Aldosterone synthesis and secretion+L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter+Arginine and proline metabolism+Biosynthesis of amino acids-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Endocrine resistance+mRNA surveillance pathway+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Long-term depression-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Pancreatic secretion-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Long-term depression+Prion disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Pancreatic secretion+Prion disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Aldosterone synthesis and secretion+Prion disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Endocrine resistance+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Long-term depression+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Endocrine resistance+Parkinson disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Long-term depression+Parkinson disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter+Arginine and proline metabolism-Parkinson disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Pancreatic secretion+Parkinson disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Aldosterone synthesis and secretion+Parkinson disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Cushing syndrome+Parkinson disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Endocrine resistance+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Long-term depression+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter+Arginine and proline metabolism-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Pancreatic secretion+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Cushing syndrome+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Endocrine resistance+RNA degradation+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter+Arginine and proline metabolism-RNA degradation+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Endocrine resistance+Alzheimer disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Long-term depression+Alzheimer disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Pancreatic secretion+Alzheimer disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Aldosterone synthesis and secretion+Alzheimer disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Cushing syndrome+Alzheimer disease+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Phospholipase D signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Endocrine resistance+Thermogenesis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter+Arginine and proline metabolism-Thermogenesis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Endocrine resistance+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Long-term depression+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter+Arginine and proline metabolism-Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Pancreatic secretion+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Cushing syndrome+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Pancreatic secretion+20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Morphine addiction+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Long-term depression+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Pancreatic secretion+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Aldosterone synthesis and secretion+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Odoribacter	IL-8	Odoribacter-Cushing syndrome+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.798	0.579	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-8	Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_scfa	serum_cytokines	0.408	0.579	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-8	Isobutyric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_scfa	serum_cytokines	0.408	0.579	no	no	no	no	no	no	HC
Kynurenic acid+stool	IL-8	Kynurenic acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.037	0.579	dn	dn	no	no	no	no	HC
L-Tryptophan+urine	IL-8	L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	urine_cometabolism	serum_cytokines	0.226	0.579	no	no	no	no	no	no	HC
Eggerthella	IL-8	Eggerthella+Bacteroides-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.912	0.579	no	no	no	no	no	no	HC
Anaerotruncus	IL-8	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.904	0.579	no	no	no	no	no	no	HC
Anaerotruncus	IL-8	Anaerotruncus-Gemmiger-Tuberculosis+Graft-versus-host disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.904	0.579	no	no	no	no	no	no	HC
Anaerotruncus	IL-8	Anaerotruncus-Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.904	0.579	no	no	no	no	no	no	HC
Anaerotruncus	IL-8	Anaerotruncus-Gemmiger-Tuberculosis-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.904	0.579	no	no	no	no	no	no	HC
Anaerotruncus	IL-8	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Viral myocarditis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.904	0.579	no	no	no	no	no	no	HC
Anaerotruncus	IL-8	Anaerotruncus-Gemmiger-Tuberculosis+Viral myocarditis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.904	0.579	no	no	no	no	no	no	HC
Anaerotruncus	IL-8	Anaerotruncus-Gemmiger-GPC+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.904	0.579	no	no	no	no	no	no	HC
Anaerotruncus	IL-8	Anaerotruncus-Gemmiger-20:1-LPA+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.904	0.579	no	no	no	no	no	no	HC
Anaerotruncus	IL-8	Anaerotruncus-Gemmiger-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.904	0.579	no	no	no	no	no	no	HC
Anaerotruncus	IL-8	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Allograft rejection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.904	0.579	no	no	no	no	no	no	HC
Anaerotruncus	IL-8	Anaerotruncus-Gemmiger-Tuberculosis+Allograft rejection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.904	0.579	no	no	no	no	no	no	HC
Anaerotruncus	IL-8	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.904	0.579	no	no	no	no	no	no	HC
Anaerotruncus	IL-8	Anaerotruncus-Gemmiger-Tuberculosis+Autoimmune thyroid disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.904	0.579	no	no	no	no	no	no	HC
Anaerotruncus	IL-8	Anaerotruncus-Gemmiger+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.904	0.579	no	no	no	no	no	no	HC
Anaerotruncus	IL-8	Anaerotruncus-Gemmiger-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.904	0.579	no	no	no	no	no	no	HC
Anaerostipes	IL-8	Anaerostipes-20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.568	0.579	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-8	Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_scfa	serum_cytokines	0.343	0.579	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-8	Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_scfa	serum_cytokines	0.343	0.579	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-8	Isovaleric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_scfa	serum_cytokines	0.343	0.579	no	no	no	no	no	no	HC
Paraprevotella	IL-8	Paraprevotella-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.118	0.579	no	no	no	no	no	no	HC
Paraprevotella	IL-8	Paraprevotella+AA+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.118	0.579	no	no	no	no	no	no	HC
Homovanillic acid+urine	IL-8	Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	urine_cometabolism	serum_cytokines	0.45	0.579	no	no	no	no	no	no	HC
Homovanillic acid+urine	IL-8	Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	urine_cometabolism	serum_cytokines	0.45	0.579	no	no	no	no	no	no	HC
TDCA+blood	IL-8	TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.155	0.579	no	up	no	no	no	no	HC
iso-LCA+blood	IL-8	iso-LCA+blood-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.507	0.579	no	no	no	no	no	no	HC
iso-LCA+blood	IL-8	iso-LCA+blood-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.507	0.579	no	no	no	no	no	no	HC
iso-LCA+blood	IL-8	iso-LCA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.507	0.579	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IL-8	¦Ø-MCA+stool-Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.919	0.579	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IL-8	¦Ø-MCA+stool-Acetic acid+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.919	0.579	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-8	Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.785	0.579	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-8	Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.785	0.579	no	no	no	no	no	no	HC
Gemmiger	IL-8	Gemmiger-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	HC
Gemmiger	IL-8	Gemmiger-Tuberculosis+Graft-versus-host disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	HC
Gemmiger	IL-8	Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	HC
Gemmiger	IL-8	Gemmiger-Tuberculosis-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	HC
Gemmiger	IL-8	Gemmiger-Staphylococcus aureus infection+Viral myocarditis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	HC
Gemmiger	IL-8	Gemmiger-Tuberculosis+Viral myocarditis-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	HC
Gemmiger	IL-8	Gemmiger-GPC+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	HC
Gemmiger	IL-8	Gemmiger-20:1-LPA+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	HC
Gemmiger	IL-8	Gemmiger-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	HC
Gemmiger	IL-8	Gemmiger-Staphylococcus aureus infection+Allograft rejection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	HC
Gemmiger	IL-8	Gemmiger-Tuberculosis+Allograft rejection-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	HC
Gemmiger	IL-8	Gemmiger-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	HC
Gemmiger	IL-8	Gemmiger-Tuberculosis+Autoimmune thyroid disease-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	HC
Gemmiger	IL-8	Gemmiger+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	HC
Gemmiger	IL-8	Gemmiger-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.595	0.579	no	no	no	no	no	no	HC
GDCA+stool	IL-8	GDCA+stool-TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.656	0.579	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-8	L-Tyrosine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.44	0.579	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-8	L-Tyrosine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.44	0.579	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-8	L-Tyrosine+stool+PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.44	0.579	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-8	L-Tyrosine+stool+20:1-LPA+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.44	0.579	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-8	L-Tyrosine+stool+8-HETE+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.44	0.579	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-8	L-Tyrosine+stool-12-ketoDCA+blood-AA+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.44	0.579	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-8	L-Tyrosine+stool+8-HETE+blood+AA+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.44	0.579	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-8	L-Tyrosine+stool+8-HETE+blood+TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_cometabolism	serum_cytokines	0.44	0.579	no	no	no	no	no	no	HC
CDCA+stool	IL-8	CDCA+stool+18:3n3+blood+AA+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.663	0.579	no	no	no	no	no	no	HC
CDCA+stool	IL-8	CDCA+stool+TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.663	0.579	no	no	no	no	no	no	HC
CDCA+stool	IL-8	CDCA+stool+nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.663	0.579	no	no	no	no	no	no	HC
CDCA+stool	IL-8	CDCA+stool+HCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.663	0.579	no	no	no	no	no	no	HC
CDCA+stool	IL-8	CDCA+stool+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.663	0.579	no	no	no	no	no	no	HC
CDCA+stool	IL-8	CDCA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.663	0.579	no	no	no	no	no	no	HC
CDCA+stool	IL-8	CDCA+stool-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.663	0.579	no	no	no	no	no	no	HC
CA+stool	IL-8	CA+stool+nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.827	0.579	no	no	no	no	no	no	HC
CA+stool	IL-8	CA+stool+HCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.827	0.579	no	no	no	no	no	no	HC
CA+stool	IL-8	CA+stool-ACA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.827	0.579	no	no	no	no	no	no	HC
CA+stool	IL-8	CA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.827	0.579	no	no	no	no	no	no	HC
CA+stool	IL-8	CA+stool+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.827	0.579	no	no	no	no	no	no	HC
CA+stool	IL-8	CA+stool-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.827	0.579	no	no	no	no	no	no	HC
CA+stool	IL-8	CA+stool+GDCA+stool-TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.827	0.579	no	no	no	no	no	no	HC
CA+stool	IL-8	CA+stool+TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.827	0.579	no	no	no	no	no	no	HC
CA+stool	IL-8	CA+stool-18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.827	0.579	no	no	no	no	no	no	HC
HDCA+blood	IL-8	HDCA+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.483	0.579	no	no	no	no	no	no	HC
HDCA+blood	IL-8	HDCA+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.483	0.579	no	no	no	no	no	no	HC
HDCA+blood	IL-8	HDCA+blood+SFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.483	0.579	no	no	no	no	no	no	HC
HDCA+blood	IL-8	HDCA+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.483	0.579	no	no	no	no	no	no	HC
UDCA+stool	IL-8	UDCA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.266	0.579	no	no	no	no	no	no	HC
UDCA+stool	IL-8	UDCA+stool+18:3n3+blood+AA+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.266	0.579	no	no	no	no	no	no	HC
LCA+blood	IL-8	LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.884	0.579	no	no	no	no	no	no	HC
nutriCA+stool	IL-8	nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	stool_bileacids	serum_cytokines	0.481	0.579	no	no	no	no	no	no	HC
GDCA+blood	IL-8	GDCA+blood+TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.632	0.579	no	no	no	no	no	no	HC
P-hydroxyhippuric acid+urine	IL-8	P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	urine_cometabolism	serum_cytokines	0.436	0.579	no	no	no	no	no	no	HC
acetic acid C2+blood	IL-8	acetic acid C2+blood-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.000193	0.579	up	dn	no	no	no	no	HC
isovaleric acid iso-C5+blood	IL-8	isovaleric acid iso-C5+blood+Sarcosine+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	serum_scfa	serum_cytokines	0.117	0.579	no	no	no	no	no	no	HC
L-Phenylalanine+urine	IL-8	L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	urine_cometabolism	serum_cytokines	0.0908	0.579	no	up	no	no	no	no	HC
Clostridium	IL-8	Clostridium+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.925	0.579	no	no	no	no	no	no	HC
Clostridium	IL-8	Clostridium-L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.925	0.579	no	no	no	no	no	no	HC
12-ketoDCA+blood	IL-8	12-ketoDCA+blood-AA+blood-FGF basic-IL-13-IL-2+IL-8	Indirect	serum_bileacids	serum_cytokines	0.517	0.579	no	no	no	no	no	no	HC
Butyricicoccus	IL-8	Butyricicoccus+d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.852	0.579	no	no	no	no	no	no	HC
3-Hydroxy-L-kynurenine+urine	IL-8	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2+IL-8	Indirect	urine_cometabolism	serum_cytokines	0.401	0.579	no	no	no	no	no	no	HC
Wautersiella	IL-8	Wautersiella+Butyricicoccus+d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2+IL-8	Indirect	Genus	serum_cytokines	0.289	0.579	no	no	no	no	no	no	HC
Blautia	Resistin	Blautia+16:0/20:5-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	1.36E-05	0.156	up	dn	dn	no	no	no	HC
Parabacteroides	Resistin	Parabacteroides+16:1/18:2-PG+blood-20:5n3+blood-Resistin	Indirect	Genus	DM-associated hormones	4.19E-05	0.156	no	up	up	no	no	no	HC
Parabacteroides	Resistin	Parabacteroides+16:1/18:2-PG+blood+Betaine+blood+Resistin	Indirect	Genus	DM-associated hormones	4.19E-05	0.156	no	up	up	no	no	no	HC
Parabacteroides	Resistin	Parabacteroides+16:0/18:1-PC+blood+n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	4.19E-05	0.156	no	up	up	no	no	no	HC
Parabacteroides	Resistin	Parabacteroides+16:1/18:2-PG+blood+n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	4.19E-05	0.156	no	up	up	no	no	no	HC
Parabacteroides	Resistin	Parabacteroides+18:1/18:2-PG+blood+n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	4.19E-05	0.156	no	up	up	no	no	no	HC
Parabacteroides	Resistin	Parabacteroides+18:0/22:6-PA+blood+EPA+blood-Resistin	Indirect	Genus	DM-associated hormones	4.19E-05	0.156	no	up	up	no	no	no	HC
Parabacteroides	Resistin	Parabacteroides+Ethanolamine+blood+L-Aspartic acid+blood+Resistin	Indirect	Genus	DM-associated hormones	4.19E-05	0.156	no	up	up	no	no	no	HC
Dorea	Resistin	Dorea-18:2-LPC+blood+n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	Dorea-Endocrine resistance+C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	Dorea-Amphetamine addiction+C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	Dorea-Chemical carcinogenesis - receptor activation+C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	"Dorea-Growth hormone synthesis, secretion and action+C-peptide-Resistin"	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	Dorea-GnRH signaling pathway+C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	Dorea-18:2-LPC+blood-20:5n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	Dorea-iso-LCA+stool-Leptin-Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	Dorea+16:0/18:3-PC+blood+Leptin-Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	Dorea+CDCA+stool+Leptin-Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	Dorea-VEGF signaling pathway+ACA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	Dorea-Fc epsilon RI signaling pathway+ACA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	"Dorea-Growth hormone synthesis, secretion and action+ACA+stool-Resistin"	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	Dorea+Legionellosis+14:0/18:2-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	Dorea-16:0-LPC+blood+DPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	Dorea-18:0-LPC+blood+DPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	Dorea-18:0-LPC+blood+18:0/20:3-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	Dorea-18:0-LPC+blood-L-Aspartic acid+blood+Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Dorea	Resistin	Dorea+Legionellosis-TMAO+blood+Resistin	Indirect	Genus	DM-associated hormones	0.00362	0.156	up	no	dn	no	no	no	HC
Faecalibacterium	Resistin	Faecalibacterium+4-hydroxybenzoic acid+stool-EPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0039	0.156	no	dn	dn	no	no	no	HC
Faecalibacterium	Resistin	Faecalibacterium+4-hydroxybenzoic acid+stool-20:5n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0039	0.156	no	dn	dn	no	no	no	HC
Faecalibacterium	Resistin	Faecalibacterium+4-hydroxybenzoic acid+stool-ACA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.0039	0.156	no	dn	dn	no	no	no	HC
TUDCA+blood	Resistin	TUDCA+blood+P-hydroxyhippuric acid+urine+Leptin-Resistin	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine+Leptin-Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Tryptophan+blood+lauric acid C12+blood+n6/n3+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+lauric acid C12+blood+n6/n3+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Phenylalanine+blood+lauric acid C12+blood+n6/n3+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+lauric acid C12+blood+n6/n3+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+lauric acid C12+blood+n6/n3+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood+lauric acid C12+blood+n6/n3+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Tryptophan+blood+MUFA%+blood+n6/n3+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+MUFA%+blood+n6/n3+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+MUFA%+blood+n6/n3+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+L-Histidine+blood+n6/n3+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Tryptophan+blood+lauric acid C12+blood+TMAO+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+lauric acid C12+blood+TMAO+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Phenylalanine+blood+lauric acid C12+blood+TMAO+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+lauric acid C12+blood+TMAO+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+lauric acid C12+blood+TMAO+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood+lauric acid C12+blood+TMAO+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+Serine+blood+TMAO+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+Serine+blood+TMAO+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+Serine+blood+TMAO+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Resistin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+L-Glutamine+blood+TMAO+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.156	no	no	dn	no	no	no	HC
Bacteroides	Resistin	Bacteroides+Systemic lupus erythematosus-C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	HC
Bacteroides	Resistin	Bacteroides+AGE-RAGE signaling pathway in diabetic complications+ACA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	HC
Bacteroides	Resistin	Bacteroides+UDCA+stool-TMAO+blood+Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	HC
Bacteroides	Resistin	Bacteroides+CDCA+stool+Leptin-Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	HC
Bacteroides	Resistin	Bacteroides+P-hydroxyhippuric acid+urine+Leptin-Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	HC
Bacteroides	Resistin	Bacteroides-Amyotrophic lateral sclerosis-Leptin-Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	HC
Bacteroides	Resistin	Bacteroides-iso-LCA+stool-Leptin-Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	HC
Bacteroides	Resistin	Bacteroides-Thermogenesis-Leptin-Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	HC
Bacteroides	Resistin	Bacteroides-HDCA+stool-n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	HC
Bacteroides	Resistin	Bacteroides-Amyotrophic lateral sclerosis-n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	HC
Bacteroides	Resistin	Bacteroides-Ribosome-n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	HC
Bacteroides	Resistin	Bacteroides-Parkinson disease-n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	HC
Bacteroides	Resistin	Bacteroides-Shigellosis-n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	HC
Bacteroides	Resistin	Bacteroides-Thermogenesis-n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	HC
Bacteroides	Resistin	Bacteroides-Coronavirus disease - COVID-19-n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	HC
Bacteroides	Resistin	Bacteroides+Blautia+16:0/20:5-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	0.000267	0.156	dn	dn	up	no	no	no	HC
Propionic acid+stool	Resistin	Propionic acid+stool+16:0/18:2-PI+blood+DPA+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.156	dn	no	up	no	no	no	HC
Propionic acid+stool	Resistin	Propionic acid+stool+iso-LCA+blood-n3+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.156	dn	no	up	no	no	no	HC
[Ruminococcus]	Resistin	[Ruminococcus]-18:0/20:4-PI+blood-20:5n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0679	0.156	no	no	dn	no	no	no	HC
[Ruminococcus]	Resistin	[Ruminococcus]+16:0/18:3-PC+blood+Leptin-Resistin	Indirect	Genus	DM-associated hormones	0.0679	0.156	no	no	dn	no	no	no	HC
[Ruminococcus]	Resistin	[Ruminococcus]-18:0/20:4-PI+blood-Leptin-Resistin	Indirect	Genus	DM-associated hormones	0.0679	0.156	no	no	dn	no	no	no	HC
[Ruminococcus]	Resistin	[Ruminococcus]-Hypotaurine+blood-Leptin-Resistin	Indirect	Genus	DM-associated hormones	0.0679	0.156	no	no	dn	no	no	no	HC
[Ruminococcus]	Resistin	[Ruminococcus]-18:0/20:4-PI+blood+n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0679	0.156	no	no	dn	no	no	no	HC
[Ruminococcus]	Resistin	[Ruminococcus]-Hypotaurine+blood+n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	0.0679	0.156	no	no	dn	no	no	no	HC
[Ruminococcus]	Resistin	[Ruminococcus]-HDCA+stool-n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0679	0.156	no	no	dn	no	no	no	HC
[Ruminococcus]	Resistin	[Ruminococcus]-Hypotaurine+blood-n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.0679	0.156	no	no	dn	no	no	no	HC
[Ruminococcus]	Resistin	[Ruminococcus]+Proteasome-C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.0679	0.156	no	no	dn	no	no	no	HC
[Ruminococcus]	Resistin	[Ruminococcus]+Proteasome-GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.0679	0.156	no	no	dn	no	no	no	HC
GUDCA+blood	Resistin	GUDCA+blood-iso-DCA+blood+n6/n3+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.156	no	no	dn	no	no	no	HC
GUDCA+blood	Resistin	GUDCA+blood-PUFA%+blood+TMAO+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.156	no	no	dn	no	no	no	HC
GUDCA+blood	Resistin	GUDCA+blood-PUFA/UFA+blood+TMAO+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.156	no	no	dn	no	no	no	HC
Acetic acid+stool	Resistin	Acetic acid+stool-Phenylacetic acid+stool+n6/n3+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.156	dn	no	no	no	no	no	HC
Acetic acid+stool	Resistin	Acetic acid+stool-Phenylacetic acid+stool-14:0/18:2-PC+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.156	dn	no	no	no	no	no	HC
Acetic acid+stool	Resistin	Acetic acid+stool-Phenylacetic acid+stool-Leptin-Resistin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.156	dn	no	no	no	no	no	HC
Acetic acid+stool	Resistin	Acetic acid+stool+iso-LCA+blood-n3+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.156	dn	no	no	no	no	no	HC
Acetic acid+stool	Resistin	Acetic acid+stool+16:0/18:2-PI+blood+DPA+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.156	dn	no	no	no	no	no	HC
Alistipes	Resistin	Alistipes-Leptin-Resistin	Indirect	Genus	DM-associated hormones	0.0114	0.156	no	up	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas-Leishmaniasis+14:0/18:2-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+18:0-LPC+blood-L-Aspartic acid+blood+Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+Diabetic cardiomyopathy-L-Aspartic acid+blood+Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+18:0-LPC+blood+18:0/20:3-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+Inflammatory mediator regulation of TRP channels+C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+Morphine addiction+C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+Long-term depression+C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+Pancreatic secretion+C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+Renal cell carcinoma-20:5n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+Renal cell carcinoma-16:0/20:5-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+Inflammatory mediator regulation of TRP channels-d18:1-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+20:5/18:0-PC+blood+EPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+20:5/18:0-PC+blood+DHA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+20:5/18:0-PC+blood-d18:0-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas-Hypotaurine+blood-Leptin-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+Diabetic cardiomyopathy-Leptin-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas-Hypotaurine+blood-n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+20:5/18:0-PC+blood+n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas-Hypotaurine+blood+n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+18:1/18:1-PC+blood+n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+16:0-LPC+blood+DPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+18:0-LPC+blood+DPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+Inflammatory mediator regulation of TRP channels+DPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+VEGF signaling pathway+ACA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+Prolactin signaling pathway+ACA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+Phospholipase D signaling pathway+ACA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+Neurotrophin signaling pathway+ACA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Butyricimonas	Resistin	Butyricimonas+Chagas disease+ACA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.17	0.156	no	no	no	no	no	no	HC
Collinsella	Resistin	Collinsella-TMAO+blood+Resistin	Indirect	Genus	DM-associated hormones	0.128	0.156	no	no	no	no	no	no	HC
iso-DCA+stool	Resistin	iso-DCA+stool-UDCA+stool-TMAO+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.156	no	no	no	no	no	no	HC
iso-DCA+stool	Resistin	iso-DCA+stool+iso-LCA+stool-Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.156	no	no	no	no	no	no	HC
LCA+stool	Resistin	"LCA+stool+9,10-EPOME+blood+d18:1-24:1-SM+blood+Resistin"	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	HC
LCA+stool	Resistin	"LCA+stool+9,10-EPOME+blood-Betaine+blood+Resistin"	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	HC
LCA+stool	Resistin	LCA+stool+16:0/18:1-PC+blood+n6/n3+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.156	no	no	no	no	no	no	HC
Akkermansia	Resistin	Akkermansia-Wnt signaling pathway+C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.23	0.156	no	no	no	no	no	no	HC
Akkermansia	Resistin	Akkermansia+Systemic lupus erythematosus-C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.23	0.156	no	no	no	no	no	no	HC
Akkermansia	Resistin	Akkermansia+Pertussis+n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.23	0.156	no	no	no	no	no	no	HC
Akkermansia	Resistin	Akkermansia-iso-LCA+blood-n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.23	0.156	no	no	no	no	no	no	HC
Akkermansia	Resistin	Akkermansia-LCA+blood-n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.23	0.156	no	no	no	no	no	no	HC
Akkermansia	Resistin	Akkermansia-Coronavirus disease - COVID-19-n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.23	0.156	no	no	no	no	no	no	HC
Akkermansia	Resistin	Akkermansia-Ribosome-n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.23	0.156	no	no	no	no	no	no	HC
Bifidobacterium	Resistin	Bifidobacterium-12-ketoDCA+blood-DPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.105	0.156	no	dn	no	no	no	no	HC
Bifidobacterium	Resistin	Bifidobacterium-18:2-LPE+blood-d18:1-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.105	0.156	no	dn	no	no	no	no	HC
Bifidobacterium	Resistin	Bifidobacterium+20:4-LPC+blood+TMAO+blood+Resistin	Indirect	Genus	DM-associated hormones	0.105	0.156	no	dn	no	no	no	no	HC
Bifidobacterium	Resistin	Bifidobacterium+20:4-LPC+blood+d18:0-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.105	0.156	no	dn	no	no	no	no	HC
Bifidobacterium	Resistin	Bifidobacterium-DCA+blood-C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.105	0.156	no	dn	no	no	no	no	HC
Bifidobacterium	Resistin	Bifidobacterium+AA+blood+DHA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.105	0.156	no	dn	no	no	no	no	HC
Bifidobacterium	Resistin	Bifidobacterium+13-HODE+blood+n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	0.105	0.156	no	dn	no	no	no	no	HC
Bifidobacterium	Resistin	Bifidobacterium-Intestinal immune network for IgA production+ACA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.105	0.156	no	dn	no	no	no	no	HC
Ruminococcus	Resistin	Ruminococcus+C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.335	0.156	no	no	no	no	no	no	HC
GCDCA+blood	Resistin	GCDCA+blood-iso-DCA+blood+n6/n3+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.156	no	no	no	no	no	no	HC
GCDCA+blood	Resistin	GCDCA+blood-MUFA%+blood+n6/n3+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.156	no	no	no	no	no	no	HC
GCDCA+blood	Resistin	GCDCA+blood-PUFA%+blood+TMAO+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.156	no	no	no	no	no	no	HC
[Prevotella]	Resistin	[Prevotella]-ACA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.367	0.156	no	no	no	no	no	no	HC
ACA+blood	Resistin	ACA+blood-P-hydroxyhippuric acid+urine+Leptin-Resistin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.156	no	no	no	no	no	no	HC
ACA+blood	Resistin	ACA+blood+iso-LCA+blood-n3+blood-Resistin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.156	no	no	no	no	no	no	HC
ACA+blood	Resistin	ACA+blood+LCA+blood-n3+blood-Resistin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.156	no	no	no	no	no	no	HC
DCA+stool	Resistin	DCA+stool-20:1-LPA+blood-d18:0-24:1-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.156	no	no	no	no	no	no	HC
DCA+stool	Resistin	DCA+stool-L-Phenylalanine+stool-Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.156	no	no	no	no	no	no	HC
DCA+stool	Resistin	DCA+stool+iso-LCA+stool-Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.156	no	no	no	no	no	no	HC
DCA+stool	Resistin	DCA+stool-8-HETE+blood+d18:1-16:0-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.156	no	no	no	no	no	no	HC
Butyric acid+stool	Resistin	Butyric acid+stool-L-Phenylalanine+stool-Leptin-Resistin	Indirect	stool_scfa	DM-associated hormones	0.102	0.156	dn	no	no	no	no	no	HC
Butyric acid+stool	Resistin	Butyric acid+stool+16:0/16:0-PC+blood+EPA+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.102	0.156	dn	no	no	no	no	no	HC
Butyric acid+stool	Resistin	Butyric acid+stool+HDCA+stool-n3+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.102	0.156	dn	no	no	no	no	no	HC
Butyric acid+stool	Resistin	Butyric acid+stool-d18:1-22:0-SM+blood+d18:1-24:1-SM+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.102	0.156	dn	no	no	no	no	no	HC
4-hydroxybenzoic acid+stool	Resistin	4-hydroxybenzoic acid+stool-ACA+stool-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.156	no	dn	no	no	no	no	HC
4-hydroxybenzoic acid+stool	Resistin	4-hydroxybenzoic acid+stool-20:5n3+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.156	no	dn	no	no	no	no	HC
4-hydroxybenzoic acid+stool	Resistin	4-hydroxybenzoic acid+stool-EPA+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.156	no	dn	no	no	no	no	HC
GCA+blood	Resistin	GCA+blood-iso-DCA+blood+n6/n3+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.156	no	no	no	no	no	no	HC
ACA+stool	Resistin	ACA+stool-Resistin	Direct	stool_bileacids	DM-associated hormones	0.417	0.156	no	no	no	no	no	no	HC
CDCA+blood	Resistin	CDCA+blood-Creatinine+blood-Leptin-Resistin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.156	no	no	no	no	no	no	HC
CDCA+blood	Resistin	CDCA+blood+DCA+blood-C-peptide-Resistin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.156	no	no	no	no	no	no	HC
CDCA+blood	Resistin	CDCA+blood-d18:1-18:1-SM+blood+n6/n3+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.156	no	no	no	no	no	no	HC
CDCA+blood	Resistin	CDCA+blood-Creatinine+blood+n6/n3+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.156	no	no	no	no	no	no	HC
capric acid C6+blood	Resistin	capric acid C6+blood-Cystine+blood+L-Aspartic acid+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.433	0.156	no	no	no	no	no	no	HC
Prevotella	Resistin	Prevotella-20:3/18:0-PC+blood+n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	HC
Prevotella	Resistin	Prevotella-20:3/18:0-PC+blood+EPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	HC
Prevotella	Resistin	Prevotella-16:0/16:0-PC+blood+EPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	HC
Prevotella	Resistin	Prevotella+12-ketoDCA+blood-DPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	HC
Prevotella	Resistin	Prevotella+Estrogen signaling pathway+DPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	HC
Prevotella	Resistin	Prevotella-18:1/18:1-PC+blood+n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	HC
Prevotella	Resistin	Prevotella+18:0/18:1-PE+blood-n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	HC
Prevotella	Resistin	Prevotella-iso-DCA+blood+n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	HC
Prevotella	Resistin	Prevotella-MUFA%+blood+n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	HC
Prevotella	Resistin	Prevotella+Estrogen signaling pathway+DHA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	HC
Prevotella	Resistin	Prevotella-18:0/20:4-PC+blood+TMAO+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	HC
Prevotella	Resistin	Prevotella-18:1/20:4-PC+blood+TMAO+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	HC
Prevotella	Resistin	Prevotella-PUFA%+blood+TMAO+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	HC
Prevotella	Resistin	Prevotella-18:1/20:4-PC+blood+d18:1-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.287	0.156	no	no	no	no	no	no	HC
TCA+blood	Resistin	TCA+blood+P-hydroxyhippuric acid+urine+Leptin-Resistin	Indirect	serum_bileacids	DM-associated hormones	0.339	0.156	no	no	no	no	no	no	HC
iso-DCA+blood	Resistin	iso-DCA+blood+n6/n3+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.156	no	no	no	no	no	no	HC
HCA+stool	Resistin	HCA+stool-iso-LCA+blood-n3+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.156	no	no	no	no	no	no	HC
HCA+stool	Resistin	HCA+stool-LCA+blood-n3+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.156	no	no	no	no	no	no	HC
HCA+stool	Resistin	HCA+stool+20:3/18:0-PC+blood+n3+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.156	no	no	no	no	no	no	HC
HCA+stool	Resistin	HCA+stool-iso-LCA+stool-Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.156	no	no	no	no	no	no	HC
HCA+stool	Resistin	HCA+stool+16:0/18:3-PC+blood+Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.156	no	no	no	no	no	no	HC
HCA+stool	Resistin	HCA+stool+18:3n3+blood+DHA+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.156	no	no	no	no	no	no	HC
HCA+stool	Resistin	HCA+stool+18:3n3+blood+EPA+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.156	no	no	no	no	no	no	HC
HCA+stool	Resistin	HCA+stool+20:3/18:0-PC+blood+EPA+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.156	no	no	no	no	no	no	HC
HCA+stool	Resistin	HCA+stool+UDCA+stool-TMAO+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.156	no	no	no	no	no	no	HC
Roseburia	Resistin	Roseburia-ACA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.495	0.156	no	no	no	no	no	no	HC
12-ketoDCA+stool	Resistin	12-ketoDCA+stool-Cystine+blood+L-Aspartic acid+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.156	no	no	no	no	no	no	HC
12-ketoDCA+stool	Resistin	12-ketoDCA+stool-CDCA+stool+Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.156	no	no	no	no	no	no	HC
GLCA+blood	Resistin	GLCA+blood+L-Glutamine+blood+TMAO+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.156	no	no	no	no	no	no	HC
GLCA+blood	Resistin	GLCA+blood+LCA+blood-n3+blood-Resistin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.156	no	no	no	no	no	no	HC
GLCA+blood	Resistin	GLCA+blood+iso-LCA+blood-n3+blood-Resistin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.156	no	no	no	no	no	no	HC
L-Tryptophan+stool	Resistin	L-Tryptophan+stool+20:4/18:0-PE+blood+d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.156	no	no	no	no	no	no	HC
L-Tryptophan+stool	Resistin	L-Tryptophan+stool-DCA+blood-C-peptide-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.156	no	no	no	no	no	no	HC
L-Tryptophan+stool	Resistin	L-Tryptophan+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.156	no	no	no	no	no	no	HC
L-Tryptophan+stool	Resistin	L-Tryptophan+stool+Phenylacetic acid+stool-Leptin-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.156	no	no	no	no	no	no	HC
L-Tryptophan+stool	Resistin	L-Tryptophan+stool-12-ketoDCA+blood-DPA+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.156	no	no	no	no	no	no	HC
L-Tryptophan+stool	Resistin	L-Tryptophan+stool+Phenylacetic acid+stool+n6/n3+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.156	no	no	no	no	no	no	HC
CA+blood	Resistin	CA+blood+LCA+blood-n3+blood-Resistin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.156	no	no	no	no	no	no	HC
GUDCA+stool	Resistin	GUDCA+stool+Phenylacetic acid+stool+n6/n3+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.156	no	dn	no	no	no	no	HC
GUDCA+stool	Resistin	GUDCA+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.156	no	dn	no	no	no	no	HC
GUDCA+stool	Resistin	GUDCA+stool+Phenylacetic acid+stool-Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.156	no	dn	no	no	no	no	HC
L-Phenylalanine+stool	Resistin	L-Phenylalanine+stool-Leptin-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.156	no	no	no	no	no	no	HC
butyric acid C4+blood	Resistin	butyric acid C4+blood-DCA+blood-C-peptide-Resistin	Indirect	serum_scfa	DM-associated hormones	0.407	0.156	no	no	no	no	no	no	HC
butyric acid C4+blood	Resistin	butyric acid C4+blood+Cystine+blood+L-Aspartic acid+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.407	0.156	no	no	no	no	no	no	HC
GCA+stool	Resistin	GCA+stool+GCDCA+stool-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.156	no	no	no	no	no	no	HC
GCA+stool	Resistin	GCA+stool+Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.156	no	no	no	no	no	no	HC
Coprococcus	Resistin	Coprococcus+16:0/20:5-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	0.612	0.156	no	no	no	no	no	no	HC
Coprococcus	Resistin	Coprococcus+20:5n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.612	0.156	no	no	no	no	no	no	HC
Coprococcus	Resistin	Coprococcus+Leptin-Resistin	Indirect	Genus	DM-associated hormones	0.612	0.156	no	no	no	no	no	no	HC
Coprococcus	Resistin	Coprococcus-Betaine+blood+Resistin	Indirect	Genus	DM-associated hormones	0.612	0.156	no	no	no	no	no	no	HC
Coprococcus	Resistin	Coprococcus-n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	0.612	0.156	no	no	no	no	no	no	HC
Coprococcus	Resistin	Coprococcus+d18:1-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.612	0.156	no	no	no	no	no	no	HC
Oscillospira	Resistin	Oscillospira+20:5n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	HC
Oscillospira	Resistin	Oscillospira+C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.62	0.156	no	no	no	no	no	no	HC
HCA+blood	Resistin	HCA+blood-MUFA%+blood+n6/n3+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.544	0.156	no	no	no	no	no	no	HC
iso-LCA+stool	Resistin	iso-LCA+stool-Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.156	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	Resistin	2-methyl-butyric acid m-C4+blood-22:2-LPA+blood-d18:0-24:1-SM+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.262	0.156	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	Resistin	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+TMAO+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.262	0.156	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	Resistin	2-methyl-butyric acid m-C4+blood+20:1+blood-DHA+blood-Resistin	Indirect	serum_scfa	DM-associated hormones	0.262	0.156	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	Resistin	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+n6/n3+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.262	0.156	no	no	no	no	no	no	HC
DCA+blood	Resistin	DCA+blood-C-peptide-Resistin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.156	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	Resistin	3-(3-Hydroxyphenyl)propanoic acid+stool+14:0/18:2-PC+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.156	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	Resistin	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/20:3-PC+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.156	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	Resistin	3-(3-Hydroxyphenyl)propanoic acid+stool+DHA+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.156	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	Resistin	3-(3-Hydroxyphenyl)propanoic acid+stool+20:2/18:0-PC+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.156	no	no	no	no	no	no	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	Resistin	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine+Leptin-Resistin"	Indirect	urine_cometabolism	DM-associated hormones	0.0125	0.156	up	up	no	no	no	no	HC
GLCA+stool	Resistin	GLCA+stool-iso-LCA+stool-Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.156	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Resistin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-Leptin-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.156	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Resistin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-Leptin-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.156	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Resistin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.156	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Resistin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+n6/n3+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool-PUFA%+blood+TMAO+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool+18:3n6+blood+20:2/18:0-PC+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool+18:3n6+blood-Betaine+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool-18:2/16:0-PC+blood+n6/n3+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool+16:0/20:4-PI+blood-n6/n3+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool-16:0/18:1-PC+blood+n6/n3+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool-18:1/18:1-PC+blood+n6/n3+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool-18:2-LPC+blood+n6/n3+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool-iso-DCA+blood+n6/n3+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool-20:0+blood+n6/n3+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool-Creatinine+blood+n6/n3+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool-Choline+blood+n6/n3+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool-Choline+blood-DHA+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool-18:2-LPC+blood-20:5n3+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool-20:0+blood-n3+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool-Choline+blood-n3+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool-18:1/18:0-PC+blood-d18:0-24:1-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
TCA+stool	Resistin	TCA+stool-Creatinine+blood-Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.156	no	no	no	no	no	no	HC
HDCA+stool	Resistin	HDCA+stool-n3+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.156	no	no	no	no	no	no	HC
Lachnospira	Resistin	Lachnospira+GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.279	0.156	no	no	no	no	no	no	HC
isobutyric acid C4+blood	Resistin	isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood-PUFA/MUFA+blood+TMAO+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.156	up	up	no	no	no	no	HC
isobutyric acid C4+blood	Resistin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+Serine+blood+TMAO+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.156	up	up	no	no	no	no	HC
isobutyric acid C4+blood	Resistin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Phenylalanine+blood+lauric acid C12+blood+TMAO+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.156	up	up	no	no	no	no	HC
isobutyric acid C4+blood	Resistin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+lauric acid C12+blood+TMAO+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.156	up	up	no	no	no	no	HC
isobutyric acid C4+blood	Resistin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Tryptophan+blood+lauric acid C12+blood+TMAO+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.156	up	up	no	no	no	no	HC
isobutyric acid C4+blood	Resistin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Phenylalanine+blood+lauric acid C12+blood+n6/n3+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.156	up	up	no	no	no	no	HC
isobutyric acid C4+blood	Resistin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+lauric acid C12+blood+n6/n3+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.156	up	up	no	no	no	no	HC
isobutyric acid C4+blood	Resistin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Tryptophan+blood+lauric acid C12+blood+n6/n3+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.156	up	up	no	no	no	no	HC
isobutyric acid C4+blood	Resistin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+MUFA%+blood+n6/n3+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.156	up	up	no	no	no	no	HC
isobutyric acid C4+blood	Resistin	isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood+MUFA%+blood+n6/n3+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.156	up	up	no	no	no	no	HC
isobutyric acid C4+blood	Resistin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Tryptophan+blood+MUFA%+blood+n6/n3+blood+Resistin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.156	up	up	no	no	no	no	HC
GCDCA+stool	Resistin	GCDCA+stool-Resistin	Direct	stool_bileacids	DM-associated hormones	0.0471	0.156	no	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	Resistin	5-Hydroxytryptamine+stool+GCDCA+stool-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.156	dn	dn	no	no	no	no	HC
Odoribacter	Resistin	Odoribacter-C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.798	0.156	no	no	no	no	no	no	HC
Isobutyric acid+stool	Resistin	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.408	0.156	no	no	no	no	no	no	HC
Isobutyric acid+stool	Resistin	Isobutyric acid+stool+Phenylacetic acid+stool-Leptin-Resistin	Indirect	stool_scfa	DM-associated hormones	0.408	0.156	no	no	no	no	no	no	HC
Isobutyric acid+stool	Resistin	Isobutyric acid+stool+Phenylacetic acid+stool+n6/n3+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.408	0.156	no	no	no	no	no	no	HC
Kynurenic acid+stool	Resistin	Kynurenic acid+stool-UDCA+stool-TMAO+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.156	dn	dn	no	no	no	no	HC
Eggerthella	Resistin	Eggerthella+Clostridium+DPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.912	0.156	no	no	no	no	no	no	HC
Eggerthella	Resistin	Eggerthella+Clostridium-d18:1-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.912	0.156	no	no	no	no	no	no	HC
 Eggerthella	Resistin	Eggerthella+Clostridium-d18:1-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	NA	0.156	NA	NA	NA	no	no	no	HC
Eggerthella	Resistin	Eggerthella+Clostridium-d18:1-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.912	0.156	no	no	no	no	no	no	HC
 Eggerthella	Resistin	Eggerthella+Clostridium-d18:1-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	NA	0.156	NA	NA	NA	no	no	no	HC
Eggerthella	Resistin	Eggerthella+Clostridium-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.912	0.156	no	no	no	no	no	no	HC
Eggerthella	Resistin	Eggerthella+Clostridium+14:0/18:2-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	0.912	0.156	no	no	no	no	no	no	HC
Eggerthella	Resistin	Eggerthella+Clostridium-d18:0-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.912	0.156	no	no	no	no	no	no	HC
Eggerthella	Resistin	Eggerthella+Clostridium+18:0/20:3-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	0.912	0.156	no	no	no	no	no	no	HC
Eggerthella	Resistin	Eggerthella+Clostridium+20:2/18:0-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	0.912	0.156	no	no	no	no	no	no	HC
Anaerotruncus	Resistin	Anaerotruncus-Gemmiger-20:1-LPA+blood-d18:0-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.904	0.156	no	no	no	no	no	no	HC
Anaerotruncus	Resistin	Anaerotruncus-Gemmiger+LCA+blood-n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.904	0.156	no	no	no	no	no	no	HC
Anaerotruncus	Resistin	Anaerotruncus-Gemmiger-L-Phenylalanine+stool-Leptin-Resistin	Indirect	Genus	DM-associated hormones	0.904	0.156	no	no	no	no	no	no	HC
Anaerostipes	Resistin	Anaerostipes-C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.568	0.156	no	no	no	no	no	no	HC
Isovaleric acid+stool	Resistin	Isovaleric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Resistin	Indirect	stool_scfa	DM-associated hormones	0.343	0.156	no	no	no	no	no	no	HC
Isovaleric acid+stool	Resistin	Isovaleric acid+stool+Phenylacetic acid+stool-Leptin-Resistin	Indirect	stool_scfa	DM-associated hormones	0.343	0.156	no	no	no	no	no	no	HC
Isovaleric acid+stool	Resistin	Isovaleric acid+stool+Phenylacetic acid+stool+n6/n3+blood+Resistin	Indirect	stool_scfa	DM-associated hormones	0.343	0.156	no	no	no	no	no	no	HC
Paraprevotella	Resistin	Paraprevotella-Prostate cancer+ACA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	HC
Paraprevotella	Resistin	"Paraprevotella-Growth hormone synthesis, secretion and action+ACA+stool-Resistin"	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	HC
Paraprevotella	Resistin	Paraprevotella-Breast cancer+ACA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	HC
Paraprevotella	Resistin	Paraprevotella-Choline metabolism in cancer+ACA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	HC
Paraprevotella	Resistin	Paraprevotella+AA+blood+DHA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	HC
Paraprevotella	Resistin	Paraprevotella+13-HODE+blood+n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	HC
Paraprevotella	Resistin	"Paraprevotella-Growth hormone synthesis, secretion and action+C-peptide-Resistin"	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	HC
Paraprevotella	Resistin	Paraprevotella-GnRH signaling pathway+C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	HC
Paraprevotella	Resistin	Paraprevotella-Chemical carcinogenesis - receptor activation+C-peptide-Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	HC
Paraprevotella	Resistin	Paraprevotella+20:4n6+blood+d18:0-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	HC
Paraprevotella	Resistin	Paraprevotella+20:4n6+blood+d18:1-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	HC
Paraprevotella	Resistin	Paraprevotella+20:4n6+blood+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	HC
Paraprevotella	Resistin	Paraprevotella+8-HETE+blood+d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.118	0.156	no	no	no	no	no	no	HC
Homovanillic acid+urine	Resistin	Homovanillic acid+urine+P-hydroxyhippuric acid+urine+Leptin-Resistin	Indirect	urine_cometabolism	DM-associated hormones	0.45	0.156	no	no	no	no	no	no	HC
iso-LCA+blood	Resistin	iso-LCA+blood-n3+blood-Resistin	Indirect	serum_bileacids	DM-associated hormones	0.507	0.156	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Resistin	"¦Ø-MCA+stool-LCA+stool+9,10-EPOME+blood-Betaine+blood+Resistin"	Indirect	stool_bileacids	DM-associated hormones	0.919	0.156	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Resistin	¦Ø-MCA+stool-Propionic acid+stool+16:0/18:2-PI+blood+DPA+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.156	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Resistin	¦Ø-MCA+stool-Acetic acid+stool+16:0/18:2-PI+blood+DPA+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.156	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Resistin	"¦Ø-MCA+stool-LCA+stool+9,10-EPOME+blood+d18:1-24:1-SM+blood+Resistin"	Indirect	stool_bileacids	DM-associated hormones	0.919	0.156	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Resistin	¦Ø-MCA+stool-Butyric acid+stool-d18:1-22:0-SM+blood+d18:1-24:1-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.156	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Resistin	¦Ø-MCA+stool-iso-DCA+stool-UDCA+stool-TMAO+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.156	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Resistin	¦Ø-MCA+stool-Acetic acid+stool-Phenylacetic acid+stool-14:0/18:2-PC+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.156	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Resistin	¦Ø-MCA+stool-Butyric acid+stool+16:0/16:0-PC+blood+EPA+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.156	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Resistin	¦Ø-MCA+stool-Butyric acid+stool+HDCA+stool-n3+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.156	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Resistin	¦Ø-MCA+stool-Propionic acid+stool+iso-LCA+blood-n3+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.156	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Resistin	¦Ø-MCA+stool-Acetic acid+stool+iso-LCA+blood-n3+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.156	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Resistin	¦Ø-MCA+stool-Acetic acid+stool-Phenylacetic acid+stool+n6/n3+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.156	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Resistin	¦Ø-MCA+stool-LCA+stool+16:0/18:1-PC+blood+n6/n3+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.156	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Resistin	¦Ø-MCA+stool-Butyric acid+stool-L-Phenylalanine+stool-Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.156	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Resistin	¦Ø-MCA+stool-iso-DCA+stool+iso-LCA+stool-Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.156	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Resistin	¦Ø-MCA+stool-Acetic acid+stool-Phenylacetic acid+stool-Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.156	no	no	no	no	no	no	HC
Phenylacetic acid+stool	Resistin	Phenylacetic acid+stool+n6/n3+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.156	no	no	no	no	no	no	HC
Phenylacetic acid+stool	Resistin	Phenylacetic acid+stool-14:0/18:2-PC+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.156	no	no	no	no	no	no	HC
Phenylacetic acid+stool	Resistin	Phenylacetic acid+stool-Leptin-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.156	no	no	no	no	no	no	HC
Gemmiger	Resistin	Gemmiger-20:1-LPA+blood-d18:0-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.595	0.156	no	no	no	no	no	no	HC
Gemmiger	Resistin	Gemmiger+LCA+blood-n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.595	0.156	no	no	no	no	no	no	HC
Gemmiger	Resistin	Gemmiger-L-Phenylalanine+stool-Leptin-Resistin	Indirect	Genus	DM-associated hormones	0.595	0.156	no	no	no	no	no	no	HC
GDCA+stool	Resistin	GDCA+stool+d18:1-16:0-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.156	no	no	no	no	no	no	HC
L-Tyrosine+stool	Resistin	L-Tyrosine+stool+20:1-LPA+blood-d18:0-24:1-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.156	no	no	no	no	no	no	HC
L-Tyrosine+stool	Resistin	L-Tyrosine+stool+20:4/18:0-PE+blood+d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.156	no	no	no	no	no	no	HC
L-Tyrosine+stool	Resistin	L-Tyrosine+stool+8-HETE+blood+d18:1-16:0-SM+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.156	no	no	no	no	no	no	HC
L-Tyrosine+stool	Resistin	L-Tyrosine+stool-DCA+blood-C-peptide-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.156	no	no	no	no	no	no	HC
L-Tyrosine+stool	Resistin	L-Tyrosine+stool-12-ketoDCA+blood-DPA+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.156	no	no	no	no	no	no	HC
L-Tyrosine+stool	Resistin	L-Tyrosine+stool+PUFA%+blood+TMAO+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.156	no	no	no	no	no	no	HC
L-Tyrosine+stool	Resistin	L-Tyrosine+stool-18:3n6+blood+20:2/18:0-PC+blood-Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.156	no	no	no	no	no	no	HC
L-Tyrosine+stool	Resistin	L-Tyrosine+stool-18:3n6+blood-Betaine+blood+Resistin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.156	no	no	no	no	no	no	HC
CDCA+stool	Resistin	CDCA+stool+Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.156	no	no	no	no	no	no	HC
CA+stool	Resistin	CA+stool+UDCA+stool-TMAO+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.156	no	no	no	no	no	no	HC
CA+stool	Resistin	CA+stool+16:0/18:3-PC+blood+Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.156	no	no	no	no	no	no	HC
CA+stool	Resistin	CA+stool+CDCA+stool+Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.156	no	no	no	no	no	no	HC
CA+stool	Resistin	CA+stool+GCA+stool+Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.156	no	no	no	no	no	no	HC
CA+stool	Resistin	CA+stool-iso-LCA+stool-Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.156	no	no	no	no	no	no	HC
CA+stool	Resistin	CA+stool+GDCA+stool+d18:1-16:0-SM+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.156	no	no	no	no	no	no	HC
CA+stool	Resistin	CA+stool+GCA+stool+GCDCA+stool-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.156	no	no	no	no	no	no	HC
CA+stool	Resistin	CA+stool-HDCA+stool-n3+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.156	no	no	no	no	no	no	HC
CA+stool	Resistin	CA+stool-iso-LCA+blood-n3+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.156	no	no	no	no	no	no	HC
CA+stool	Resistin	CA+stool-LCA+blood-n3+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.156	no	no	no	no	no	no	HC
HDCA+blood	Resistin	HDCA+blood+L-Aspartic acid+blood+Resistin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.156	no	no	no	no	no	no	HC
UDCA+stool	Resistin	UDCA+stool-TMAO+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.156	no	no	no	no	no	no	HC
LCA+blood	Resistin	LCA+blood-n3+blood-Resistin	Indirect	serum_bileacids	DM-associated hormones	0.884	0.156	no	no	no	no	no	no	HC
nutriCA+stool	Resistin	"nutriCA+stool-9,10-EPOME+blood-Betaine+blood+Resistin"	Indirect	stool_bileacids	DM-associated hormones	0.481	0.156	no	no	no	no	no	no	HC
nutriCA+stool	Resistin	"nutriCA+stool-9,10-EPOME+blood+d18:1-24:1-SM+blood+Resistin"	Indirect	stool_bileacids	DM-associated hormones	0.481	0.156	no	no	no	no	no	no	HC
nutriCA+stool	Resistin	nutriCA+stool+UDCA+stool-TMAO+blood+Resistin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.156	no	no	no	no	no	no	HC
nutriCA+stool	Resistin	nutriCA+stool+18:3n3+blood+EPA+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.156	no	no	no	no	no	no	HC
nutriCA+stool	Resistin	nutriCA+stool+20:3/18:0-PC+blood+EPA+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.156	no	no	no	no	no	no	HC
nutriCA+stool	Resistin	nutriCA+stool+18:3n3+blood+DHA+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.156	no	no	no	no	no	no	HC
nutriCA+stool	Resistin	nutriCA+stool-iso-LCA+blood-n3+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.156	no	no	no	no	no	no	HC
nutriCA+stool	Resistin	nutriCA+stool-LCA+blood-n3+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.156	no	no	no	no	no	no	HC
nutriCA+stool	Resistin	nutriCA+stool+20:3/18:0-PC+blood+n3+blood-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.156	no	no	no	no	no	no	HC
nutriCA+stool	Resistin	nutriCA+stool+16:0/18:3-PC+blood+Leptin-Resistin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.156	no	no	no	no	no	no	HC
P-hydroxyhippuric acid+urine	Resistin	P-hydroxyhippuric acid+urine+Leptin-Resistin	Indirect	urine_cometabolism	DM-associated hormones	0.436	0.156	no	no	no	no	no	no	HC
acetic acid C2+blood	Resistin	acetic acid C2+blood+n3+blood-Resistin	Indirect	serum_scfa	DM-associated hormones	0.000193	0.156	up	dn	no	no	no	no	HC
Clostridium	Resistin	Clostridium+18:0/20:3-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	HC
Clostridium	Resistin	Clostridium+14:0/18:2-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	HC
Clostridium	Resistin	Clostridium+20:2/18:0-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	HC
Clostridium	Resistin	Clostridium-d18:1-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	HC
 Clostridium	Resistin	Clostridium-d18:1-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	NA	0.156	NA	NA	NA	no	no	no	HC
Clostridium	Resistin	Clostridium-d18:1-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	HC
 Clostridium	Resistin	Clostridium-d18:1-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	NA	0.156	NA	NA	NA	no	no	no	HC
Clostridium	Resistin	Clostridium-d18:1-16:0-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	HC
Clostridium	Resistin	Clostridium-d18:0-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	HC
Clostridium	Resistin	Clostridium+DPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.925	0.156	no	no	no	no	no	no	HC
12-ketoDCA+blood	Resistin	12-ketoDCA+blood-DPA+blood-Resistin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.156	no	no	no	no	no	no	HC
Butyricicoccus	Resistin	Butyricicoccus-Hepatocellular carcinoma+GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	HC
Butyricicoccus	Resistin	Butyricicoccus-Focal adhesion+GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	HC
Butyricicoccus	Resistin	Butyricicoccus-Rap1 signaling pathway+GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	HC
Butyricicoccus	Resistin	Butyricicoccus-Leukocyte transendothelial migration+GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	HC
Butyricicoccus	Resistin	Butyricicoccus-Oxytocin signaling pathway+GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	HC
Butyricicoccus	Resistin	Butyricicoccus+18:0/20:2-PC+blood+18:0/20:3-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	HC
Butyricicoccus	Resistin	Butyricicoccus+d18:1-22:0-SM+blood+d18:1-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	HC
Butyricicoccus	Resistin	Butyricicoccus+18:0/20:2-PC+blood+20:2/18:0-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	HC
Butyricicoccus	Resistin	Butyricicoccus-HDCA+blood+L-Aspartic acid+blood+Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	HC
Butyricicoccus	Resistin	Butyricicoccus-18:2/16:0-PC+blood+n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	HC
Butyricicoccus	Resistin	Butyricicoccus-18:2-LPC+blood+n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	HC
Butyricicoccus	Resistin	Butyricicoccus-18:2-LPC+blood-20:5n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	HC
Butyricicoccus	Resistin	Butyricicoccus-16:0-LPC+blood+DPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	HC
Butyricicoccus	Resistin	Butyricicoccus-18:2n6c+blood+DPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.852	0.156	no	no	no	no	no	no	HC
Wautersiella	Resistin	Wautersiella+Butyricicoccus-Hepatocellular carcinoma+GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.289	0.156	no	no	no	no	no	no	HC
Wautersiella	Resistin	Wautersiella+Butyricicoccus-Focal adhesion+GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.289	0.156	no	no	no	no	no	no	HC
Wautersiella	Resistin	Wautersiella+Butyricicoccus-Rap1 signaling pathway+GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.289	0.156	no	no	no	no	no	no	HC
Wautersiella	Resistin	Wautersiella+Butyricicoccus-Leukocyte transendothelial migration+GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.289	0.156	no	no	no	no	no	no	HC
Wautersiella	Resistin	Wautersiella+Butyricicoccus-Oxytocin signaling pathway+GCDCA+stool-Resistin	Indirect	Genus	DM-associated hormones	0.289	0.156	no	no	no	no	no	no	HC
Wautersiella	Resistin	Wautersiella+Butyricicoccus+18:0/20:2-PC+blood+18:0/20:3-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	0.289	0.156	no	no	no	no	no	no	HC
Wautersiella	Resistin	Wautersiella+Butyricicoccus+d18:1-22:0-SM+blood+d18:1-24:1-SM+blood+Resistin	Indirect	Genus	DM-associated hormones	0.289	0.156	no	no	no	no	no	no	HC
Wautersiella	Resistin	Wautersiella+Butyricicoccus+18:0/20:2-PC+blood+20:2/18:0-PC+blood-Resistin	Indirect	Genus	DM-associated hormones	0.289	0.156	no	no	no	no	no	no	HC
Wautersiella	Resistin	Wautersiella+Butyricicoccus-HDCA+blood+L-Aspartic acid+blood+Resistin	Indirect	Genus	DM-associated hormones	0.289	0.156	no	no	no	no	no	no	HC
Wautersiella	Resistin	Wautersiella+Butyricicoccus-18:2/16:0-PC+blood+n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	0.289	0.156	no	no	no	no	no	no	HC
Wautersiella	Resistin	Wautersiella+Butyricicoccus-18:2-LPC+blood+n6/n3+blood+Resistin	Indirect	Genus	DM-associated hormones	0.289	0.156	no	no	no	no	no	no	HC
Wautersiella	Resistin	Wautersiella+Butyricicoccus-18:2-LPC+blood-20:5n3+blood-Resistin	Indirect	Genus	DM-associated hormones	0.289	0.156	no	no	no	no	no	no	HC
Wautersiella	Resistin	Wautersiella+Butyricicoccus-16:0-LPC+blood+DPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.289	0.156	no	no	no	no	no	no	HC
Wautersiella	Resistin	Wautersiella+Butyricicoccus-18:2n6c+blood+DPA+blood-Resistin	Indirect	Genus	DM-associated hormones	0.289	0.156	no	no	no	no	no	no	HC
Blautia	Insulin	Blautia+Peroxisome-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	HC
Blautia	Insulin	Blautia-Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	HC
Blautia	Insulin	Blautia-Cushing syndrome+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	HC
Blautia	Insulin	Blautia+Arginine and proline metabolism-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	1.36E-05	0.00058	up	dn	dn	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-Phosphatidylinositol signaling system+Melanogenesis+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids-Melanogenesis+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-Phosphatidylinositol signaling system-Neutrophil extracellular trap formation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids+Neutrophil extracellular trap formation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-RNA degradation-Neutrophil extracellular trap formation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Carbon metabolism+Neutrophil extracellular trap formation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-mRNA surveillance pathway-Neutrophil extracellular trap formation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-Phosphatidylinositol signaling system+Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids-Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-RNA degradation+Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Carbon metabolism-Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Glycolysis / Gluconeogenesis-Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-Pathways in cancer+Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-mRNA surveillance pathway+Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-Phosphatidylinositol signaling system+Aldosterone synthesis and secretion+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids-Aldosterone synthesis and secretion+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-RNA degradation+Aldosterone synthesis and secretion+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Carbon metabolism-Aldosterone synthesis and secretion+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Glycolysis / Gluconeogenesis-Aldosterone synthesis and secretion+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-mRNA surveillance pathway+Aldosterone synthesis and secretion+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-Phosphatidylinositol signaling system+Cushing syndrome+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids-Cushing syndrome+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Carbon metabolism-Cushing syndrome+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-mRNA surveillance pathway+Cushing syndrome+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids+Antigen processing and presentation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-Phosphatidylinositol signaling system+Amphetamine addiction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids-Amphetamine addiction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-RNA degradation+Amphetamine addiction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Carbon metabolism-Amphetamine addiction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Glycolysis / Gluconeogenesis-Amphetamine addiction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-mRNA surveillance pathway+Amphetamine addiction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids+Fc gamma R-mediated phagocytosis-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-RNA degradation-Fc gamma R-mediated phagocytosis-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Carbon metabolism+Fc gamma R-mediated phagocytosis-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-mRNA surveillance pathway-Fc gamma R-mediated phagocytosis-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids-Endocrine resistance+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Carbon metabolism-Endocrine resistance+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Glycolysis / Gluconeogenesis-Endocrine resistance+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids+NOD-like receptor signaling pathway-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-RNA degradation-NOD-like receptor signaling pathway-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids-Long-term depression+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Carbon metabolism-Long-term depression+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Glycolysis / Gluconeogenesis-Long-term depression+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids-Morphine addiction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-Phosphatidylinositol signaling system+Wnt signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids-Wnt signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-RNA degradation+Wnt signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Carbon metabolism-Wnt signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Glycolysis / Gluconeogenesis-Wnt signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-mRNA surveillance pathway+Wnt signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids+Osteoclast differentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-Phosphatidylinositol signaling system+GnRH signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids-GnRH signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Carbon metabolism-GnRH signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Glycolysis / Gluconeogenesis-GnRH signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-mRNA surveillance pathway+GnRH signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids+Peroxisome-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-RNA degradation-Peroxisome-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-mRNA surveillance pathway-Peroxisome-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids-Pancreatic secretion+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-RNA degradation+Pancreatic secretion+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Carbon metabolism-Pancreatic secretion+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Glycolysis / Gluconeogenesis-Pancreatic secretion+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-mRNA surveillance pathway+Pancreatic secretion+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	"Parabacteroides-Phosphatidylinositol signaling system+Growth hormone synthesis, secretion and action+C-peptide+Insulin"	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	"Parabacteroides+Biosynthesis of amino acids-Growth hormone synthesis, secretion and action+C-peptide+Insulin"	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	"Parabacteroides+Carbon metabolism-Growth hormone synthesis, secretion and action+C-peptide+Insulin"	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	"Parabacteroides+Glycolysis / Gluconeogenesis-Growth hormone synthesis, secretion and action+C-peptide+Insulin"	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids+Systemic lupus erythematosus-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-Colorectal cancer-Systemic lupus erythematosus-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Carbon metabolism+Systemic lupus erythematosus-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-mRNA surveillance pathway-Systemic lupus erythematosus-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-Phosphatidylinositol signaling system+Inflammatory mediator regulation of TRP channels+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Biosynthesis of amino acids-Inflammatory mediator regulation of TRP channels+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-RNA degradation+Inflammatory mediator regulation of TRP channels+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides+Carbon metabolism-Inflammatory mediator regulation of TRP channels+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-mRNA surveillance pathway+Inflammatory mediator regulation of TRP channels+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Parabacteroides	Insulin	Parabacteroides-RNA degradation+Proteasome-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	4.19E-05	0.00058	no	up	up	up	up	no	HC
Dorea	Insulin	Dorea-Endocrine resistance+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.00362	0.00058	up	no	dn	up	up	no	HC
Dorea	Insulin	Dorea-Amphetamine addiction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.00362	0.00058	up	no	dn	up	up	no	HC
Dorea	Insulin	Dorea-Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.00362	0.00058	up	no	dn	up	up	no	HC
Dorea	Insulin	"Dorea-Growth hormone synthesis, secretion and action+C-peptide+Insulin"	Indirect	Genus	DM-associated hormones	0.00362	0.00058	up	no	dn	up	up	no	HC
Dorea	Insulin	Dorea-GnRH signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.00362	0.00058	up	no	dn	up	up	no	HC
Faecalibacterium	Insulin	Faecalibacterium-Staphylococcus aureus infection+Systemic lupus erythematosus-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	HC
Faecalibacterium	Insulin	Faecalibacterium+4-hydroxybenzoic acid+stool-ACA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	HC
Faecalibacterium	Insulin	Faecalibacterium-Staphylococcus aureus infection-Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0039	0.00058	no	dn	dn	up	up	no	HC
Bacteroides	Insulin	Bacteroides+Systemic lupus erythematosus-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.000267	0.00058	dn	dn	up	up	up	no	HC
Propionic acid+stool	Insulin	Propionic acid+stool+16:0/18:2-PI+blood-16:1/16:1-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.00058	dn	no	up	up	up	no	HC
Propionic acid+stool	Insulin	Propionic acid+stool-18:0/20:5-PC+blood+butyric acid C4+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.00058	dn	no	up	up	up	no	HC
Propionic acid+stool	Insulin	Propionic acid+stool+16:0/18:2-PI+blood-18:1/18:0-PS+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.00058	dn	no	up	up	up	no	HC
[Ruminococcus]	Insulin	[Ruminococcus]+Proteasome-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0679	0.00058	no	no	dn	up	up	no	HC
Acetic acid+stool	Insulin	Acetic acid+stool-18:0/20:5-PC+blood+butyric acid C4+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.00058	dn	no	no	up	up	no	HC
Acetic acid+stool	Insulin	Acetic acid+stool+16:0/18:2-PI+blood-16:1/16:1-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.00058	dn	no	no	up	up	no	HC
Acetic acid+stool	Insulin	Acetic acid+stool+Butyric acid+stool-L-Tryptophan+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.00058	dn	no	no	up	up	no	HC
Acetic acid+stool	Insulin	Acetic acid+stool+Butyric acid+stool-L-Phenylalanine+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.00058	dn	no	no	up	up	no	HC
Acetic acid+stool	Insulin	Acetic acid+stool+16:0/18:2-PI+blood-18:1/18:0-PS+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.00058	dn	no	no	up	up	no	HC
Alistipes	Insulin	Alistipes-GABAergic synapse-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0114	0.00058	no	up	no	up	up	no	HC
Alistipes	Insulin	Alistipes-Peroxisome-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0114	0.00058	no	up	no	up	up	no	HC
Alistipes	Insulin	Alistipes-NOD-like receptor signaling pathway-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0114	0.00058	no	up	no	up	up	no	HC
Alistipes	Insulin	Alistipes-Olfactory transduction-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.0114	0.00058	no	up	no	up	up	no	HC
Butyricimonas	Insulin	Butyricimonas+Inflammatory mediator regulation of TRP channels+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	HC
Butyricimonas	Insulin	Butyricimonas+Morphine addiction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	HC
Butyricimonas	Insulin	Butyricimonas+Long-term depression+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	HC
Butyricimonas	Insulin	Butyricimonas+Pancreatic secretion+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.17	0.00058	no	no	no	up	up	no	HC
Collinsella	Insulin	Collinsella+18:0/18:0-PS+blood-DCA+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.128	0.00058	no	no	no	up	up	no	HC
Collinsella	Insulin	Collinsella+Porphyrin and chlorophyll metabolism+Gap junction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.128	0.00058	no	no	no	up	up	no	HC
Collinsella	Insulin	"Collinsella+Glycine, serine and threonine metabolism+Gap junction+C-peptide+Insulin"	Indirect	Genus	DM-associated hormones	0.128	0.00058	no	no	no	up	up	no	HC
Collinsella	Insulin	"Collinsella+Glycine, serine and threonine metabolism-Arginine and proline metabolism-C-peptide+Insulin"	Indirect	Genus	DM-associated hormones	0.128	0.00058	no	no	no	up	up	no	HC
Collinsella	Insulin	Collinsella+Porphyrin and chlorophyll metabolism-NOD-like receptor signaling pathway-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.128	0.00058	no	no	no	up	up	no	HC
Collinsella	Insulin	"Collinsella+Glycine, serine and threonine metabolism-NOD-like receptor signaling pathway-C-peptide+Insulin"	Indirect	Genus	DM-associated hormones	0.128	0.00058	no	no	no	up	up	no	HC
Collinsella	Insulin	Collinsella+Porphyrin and chlorophyll metabolism-Olfactory transduction-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.128	0.00058	no	no	no	up	up	no	HC
Collinsella	Insulin	"Collinsella+Glycine, serine and threonine metabolism-Olfactory transduction-C-peptide+Insulin"	Indirect	Genus	DM-associated hormones	0.128	0.00058	no	no	no	up	up	no	HC
Collinsella	Insulin	Collinsella+Porphyrin and chlorophyll metabolism-Osteoclast differentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.128	0.00058	no	no	no	up	up	no	HC
Collinsella	Insulin	"Collinsella+Glycine, serine and threonine metabolism-Osteoclast differentiation-C-peptide+Insulin"	Indirect	Genus	DM-associated hormones	0.128	0.00058	no	no	no	up	up	no	HC
Collinsella	Insulin	Collinsella+Porphyrin and chlorophyll metabolism-Fc gamma R-mediated phagocytosis-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.128	0.00058	no	no	no	up	up	no	HC
Collinsella	Insulin	"Collinsella+Glycine, serine and threonine metabolism-Fc gamma R-mediated phagocytosis-C-peptide+Insulin"	Indirect	Genus	DM-associated hormones	0.128	0.00058	no	no	no	up	up	no	HC
iso-DCA+stool	Insulin	iso-DCA+stool-L-Tryptophan+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.00058	no	no	no	up	up	no	HC
LCA+stool	Insulin	LCA+stool+16:0/18:2-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.00058	no	no	no	up	up	no	HC
LCA+stool	Insulin	LCA+stool+16:0/18:1-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.00058	no	no	no	up	up	no	HC
LCA+stool	Insulin	LCA+stool+16:0/18:1-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.00058	no	no	no	up	up	no	HC
LCA+stool	Insulin	LCA+stool+18:0/16:0-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.00058	no	no	no	up	up	no	HC
LCA+stool	Insulin	LCA+stool+16:0/18:1-PC+blood-CDCA+blood+DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.00058	no	no	no	up	up	no	HC
LCA+stool	Insulin	LCA+stool+18:0/16:0-PC+blood-CDCA+blood+DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.00058	no	no	no	up	up	no	HC
LCA+stool	Insulin	LCA+stool-nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.00058	no	no	no	up	up	no	HC
LCA+stool	Insulin	LCA+stool-nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.00058	no	no	no	up	up	no	HC
Akkermansia	Insulin	Akkermansia-Wnt signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.23	0.00058	no	no	no	up	up	no	HC
Akkermansia	Insulin	Akkermansia+Systemic lupus erythematosus-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.23	0.00058	no	no	no	up	up	no	HC
Bifidobacterium	Insulin	Bifidobacterium-DCA+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.105	0.00058	no	dn	no	up	up	no	HC
Ruminococcus	Insulin	Ruminococcus+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.335	0.00058	no	no	no	up	up	no	HC
[Prevotella]	Insulin	"[Prevotella]-Growth hormone synthesis, secretion and action+C-peptide+Insulin"	Indirect	Genus	DM-associated hormones	0.367	0.00058	no	no	no	up	up	no	HC
[Prevotella]	Insulin	[Prevotella]-Aldosterone synthesis and secretion+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.367	0.00058	no	no	no	up	up	no	HC
[Prevotella]	Insulin	[Prevotella]-GnRH signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.367	0.00058	no	no	no	up	up	no	HC
[Prevotella]	Insulin	[Prevotella]-ACA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.367	0.00058	no	no	no	up	up	no	HC
[Prevotella]	Insulin	[Prevotella]-Gap junction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.367	0.00058	no	no	no	up	up	no	HC
[Prevotella]	Insulin	[Prevotella]-Morphine addiction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.367	0.00058	no	no	no	up	up	no	HC
DCA+stool	Insulin	DCA+stool-L-Tyrosine+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.00058	no	no	no	up	up	no	HC
DCA+stool	Insulin	DCA+stool-L-Phenylalanine+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.00058	no	no	no	up	up	no	HC
DCA+stool	Insulin	DCA+stool-L-Tryptophan+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.00058	no	no	no	up	up	no	HC
Butyric acid+stool	Insulin	Butyric acid+stool-L-Tryptophan+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.102	0.00058	dn	no	no	up	up	no	HC
Butyric acid+stool	Insulin	Butyric acid+stool-L-Phenylalanine+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.102	0.00058	dn	no	no	up	up	no	HC
4-hydroxybenzoic acid+stool	Insulin	4-hydroxybenzoic acid+stool-ACA+stool+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.00058	no	dn	no	up	up	no	HC
ACA+stool	Insulin	ACA+stool+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.00058	no	no	no	up	up	no	HC
CDCA+blood	Insulin	CDCA+blood+DCA+blood-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-Lysosome+Systemic lupus erythematosus-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-B cell receptor signaling pathway-Melanogenesis+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-IL-17 signaling pathway-Melanogenesis+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella+Estrogen signaling pathway+Melanogenesis+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-IL-17 signaling pathway-Amphetamine addiction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella+Estrogen signaling pathway+Amphetamine addiction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-Lysosome-Amphetamine addiction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-IL-17 signaling pathway-Cushing syndrome+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-Lysosome-Cushing syndrome+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-IL-17 signaling pathway+GABAergic synapse-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-Lysosome+GABAergic synapse-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-IL-17 signaling pathway+Fc gamma R-mediated phagocytosis-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-Lysosome+Fc gamma R-mediated phagocytosis-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-IL-17 signaling pathway+Olfactory transduction-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-Lysosome+Olfactory transduction-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella+12-ketoDCA+blood+DCA+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-20:3/18:0-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-L-Tryptophan+stool-DCA+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-16:1/16:1-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-Lysosome+Osteoclast differentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella+Estrogen signaling pathway+Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-Lysosome+NOD-like receptor signaling pathway-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
Prevotella	Insulin	Prevotella-Lysosome+Neutrophil extracellular trap formation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.287	0.00058	no	no	no	up	up	no	HC
HCA+stool	Insulin	HCA+stool+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.00058	no	no	no	up	up	no	HC
HCA+stool	Insulin	HCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.00058	no	no	no	up	up	no	HC
Roseburia	Insulin	Roseburia-ACA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.495	0.00058	no	no	no	up	up	no	HC
12-ketoDCA+stool	Insulin	12-ketoDCA+stool-CA+stool+GCA+stool+GCDCA+stool+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.00058	no	no	no	up	up	no	HC
12-ketoDCA+stool	Insulin	12-ketoDCA+stool-CDCA+stool+GCA+stool+GCDCA+stool+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.00058	no	no	no	up	up	no	HC
12-ketoDCA+stool	Insulin	12-ketoDCA+stool-15-HETE+blood-18:0/18:0-PS+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.00058	no	no	no	up	up	no	HC
12-ketoDCA+stool	Insulin	12-ketoDCA+stool-15-HETE+blood+butyric acid C4+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.00058	no	no	no	up	up	no	HC
12-ketoDCA+stool	Insulin	12-ketoDCA+stool-CDCA+stool+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.00058	no	no	no	up	up	no	HC
12-ketoDCA+stool	Insulin	12-ketoDCA+stool+DCA+stool-L-Tryptophan+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.00058	no	no	no	up	up	no	HC
12-ketoDCA+stool	Insulin	12-ketoDCA+stool+DCA+stool-L-Phenylalanine+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.00058	no	no	no	up	up	no	HC
12-ketoDCA+stool	Insulin	12-ketoDCA+stool+DCA+stool-L-Tyrosine+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.00058	no	no	no	up	up	no	HC
L-Tryptophan+stool	Insulin	L-Tryptophan+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.00058	no	no	no	up	up	no	HC
CA+blood	Insulin	CA+blood+CDCA+blood+DCA+blood-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.00058	no	no	no	up	up	no	HC
GUDCA+stool	Insulin	GUDCA+stool+L-Tryptophan+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.00058	no	dn	no	up	up	no	HC
L-Phenylalanine+stool	Insulin	L-Phenylalanine+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.00058	no	no	no	up	up	no	HC
butyric acid C4+blood	Insulin	butyric acid C4+blood-DCA+blood-C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.407	0.00058	no	no	no	up	up	no	HC
GCA+stool	Insulin	GCA+stool+GCDCA+stool+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus-Lysosome-Amphetamine addiction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus+Lachnospira-Herpes simplex virus 1 infection-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus+Lachnospira+GCDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus+Ribosome biogenesis in eukaryotes-GCDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus-Lysosome-Cushing syndrome+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus+Lachnospira-Proteasome-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus-Lysosome+Systemic lupus erythematosus-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus-Influenza A+Systemic lupus erythematosus-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus-Lysosome+Fc gamma R-mediated phagocytosis-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus+Ribosome biogenesis in eukaryotes-Fc gamma R-mediated phagocytosis-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus-Lysosome+GABAergic synapse-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus-Lysosome+Neutrophil extracellular trap formation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus+Ribosome biogenesis in eukaryotes-Neutrophil extracellular trap formation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus-Lysosome+Osteoclast differentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus+Ribosome biogenesis in eukaryotes-Osteoclast differentiation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus-Lysosome+NOD-like receptor signaling pathway-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus-Lysosome+Olfactory transduction-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Coprococcus	Insulin	Coprococcus+Primary immunodeficiency-ACA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.612	0.00058	no	no	no	up	up	no	HC
Oscillospira	Insulin	Oscillospira+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.62	0.00058	no	no	no	up	up	no	HC
iso-LCA+stool	Insulin	iso-LCA+stool-16:0/18:3-PC+blood+20:3/18:0-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.00058	no	no	no	up	up	no	HC
iso-LCA+stool	Insulin	iso-LCA+stool-nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.00058	no	no	no	up	up	no	HC
iso-LCA+stool	Insulin	iso-LCA+stool-16:0/18:3-PC+blood+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.00058	no	no	no	up	up	no	HC
iso-LCA+stool	Insulin	iso-LCA+stool-nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.00058	no	no	no	up	up	no	HC
iso-LCA+stool	Insulin	iso-LCA+stool-UDCA+stool+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.72	0.00058	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	Insulin	2-methyl-butyric acid m-C4+blood+butyric acid C4+blood-DCA+blood-C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.262	0.00058	no	no	no	up	up	no	HC
DCA+blood	Insulin	DCA+blood-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.00058	no	no	no	up	up	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	Insulin	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/22:6-PC+blood-20:2/18:3-PE+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.00058	no	no	no	up	up	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	Insulin	3-(3-Hydroxyphenyl)propanoic acid+stool+14:0+blood+16:0+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.00058	no	no	no	up	up	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	Insulin	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/22:6-PC+blood-20:0/20:4-PE+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.00058	no	no	no	up	up	no	HC
GLCA+stool	Insulin	GLCA+stool-LCA+stool-nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.00058	no	no	no	up	up	no	HC
GLCA+stool	Insulin	GLCA+stool-iso-LCA+stool-nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.00058	no	no	no	up	up	no	HC
GLCA+stool	Insulin	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+20:3/18:0-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.00058	no	no	no	up	up	no	HC
GLCA+stool	Insulin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-CDCA+blood+DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.00058	no	no	no	up	up	no	HC
GLCA+stool	Insulin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-CDCA+blood+DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.00058	no	no	no	up	up	no	HC
GLCA+stool	Insulin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.00058	no	no	no	up	up	no	HC
GLCA+stool	Insulin	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.00058	no	no	no	up	up	no	HC
GLCA+stool	Insulin	GLCA+stool-iso-LCA+stool-UDCA+stool+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.00058	no	no	no	up	up	no	HC
GLCA+stool	Insulin	GLCA+stool-LCA+stool-nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.00058	no	no	no	up	up	no	HC
GLCA+stool	Insulin	GLCA+stool-iso-LCA+stool-nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.00058	no	no	no	up	up	no	HC
GLCA+stool	Insulin	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.00058	no	no	no	up	up	no	HC
GLCA+stool	Insulin	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.00058	no	no	no	up	up	no	HC
GLCA+stool	Insulin	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.00058	no	no	no	up	up	no	HC
Indole-3-Acetic acid+stool	Insulin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.00058	no	no	no	up	up	no	HC
Indole-3-Acetic acid+stool	Insulin	Indole-3-Acetic acid+stool+L-Tryptophan+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.00058	no	no	no	up	up	no	HC
TCA+stool	Insulin	TCA+stool+16:0/20:4-PI+blood-16:1/16:1-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.00058	no	no	no	up	up	no	HC
TCA+stool	Insulin	TCA+stool-16:0/18:1-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.00058	no	no	no	up	up	no	HC
TCA+stool	Insulin	TCA+stool-16:0/18:2-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.00058	no	no	no	up	up	no	HC
TCA+stool	Insulin	TCA+stool-16:0/18:1-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.00058	no	no	no	up	up	no	HC
TCA+stool	Insulin	TCA+stool-18:0/16:0-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.00058	no	no	no	up	up	no	HC
TCA+stool	Insulin	TCA+stool-18:1/18:0-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.00058	no	no	no	up	up	no	HC
TCA+stool	Insulin	TCA+stool-16:0/18:1-PC+blood-CDCA+blood+DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.00058	no	no	no	up	up	no	HC
TCA+stool	Insulin	TCA+stool-18:0/16:0-PC+blood-CDCA+blood+DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.00058	no	no	no	up	up	no	HC
TCA+stool	Insulin	TCA+stool-18:1/18:1-PC+blood-20:4/18:0-PE+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.00058	no	no	no	up	up	no	HC
TCA+stool	Insulin	TCA+stool-20:0+blood-20:4-LPA+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.00058	no	no	no	up	up	no	HC
TCA+stool	Insulin	TCA+stool-20:0+blood-20:3/18:0-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.00058	no	no	no	up	up	no	HC
HDCA+stool	Insulin	HDCA+stool+16:0/18:1-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.00058	no	no	no	up	up	no	HC
HDCA+stool	Insulin	HDCA+stool+18:0/16:0-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.00058	no	no	no	up	up	no	HC
HDCA+stool	Insulin	HDCA+stool+16:0/20:4-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.00058	no	no	no	up	up	no	HC
HDCA+stool	Insulin	HDCA+stool+16:0/18:1-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.00058	no	no	no	up	up	no	HC
HDCA+stool	Insulin	HDCA+stool+16:0/18:1-PC+blood-CDCA+blood+DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.00058	no	no	no	up	up	no	HC
HDCA+stool	Insulin	HDCA+stool+18:0/16:0-PC+blood-CDCA+blood+DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.00058	no	no	no	up	up	no	HC
HDCA+stool	Insulin	HDCA+stool+iso-DCA+stool-L-Tryptophan+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.00058	no	no	no	up	up	no	HC
HDCA+stool	Insulin	HDCA+stool-16:0/18:3-PC+blood+20:3/18:0-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.00058	no	no	no	up	up	no	HC
HDCA+stool	Insulin	HDCA+stool-nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.00058	no	no	no	up	up	no	HC
HDCA+stool	Insulin	HDCA+stool-16:0/18:3-PC+blood+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.00058	no	no	no	up	up	no	HC
HDCA+stool	Insulin	HDCA+stool-nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.00058	no	no	no	up	up	no	HC
Lachnospira	Insulin	Lachnospira-Proteasome-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	HC
Lachnospira	Insulin	Lachnospira+GCDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	HC
Lachnospira	Insulin	Lachnospira-Herpes simplex virus 1 infection-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.279	0.00058	no	no	no	up	up	no	HC
GCDCA+stool	Insulin	GCDCA+stool+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.00058	no	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	Insulin	5-Hydroxytryptamine+stool+GCDCA+stool+C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.00058	dn	dn	no	up	up	no	HC
Odoribacter	Insulin	Odoribacter-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.798	0.00058	no	no	no	up	up	no	HC
Isobutyric acid+stool	Insulin	Isobutyric acid+stool+Isovaleric acid+stool-nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.408	0.00058	no	no	no	up	up	no	HC
Isobutyric acid+stool	Insulin	Isobutyric acid+stool+Isovaleric acid+stool-nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.408	0.00058	no	no	no	up	up	no	HC
Isobutyric acid+stool	Insulin	Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood-20:3/18:0-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.408	0.00058	no	no	no	up	up	no	HC
Isobutyric acid+stool	Insulin	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/20:4-PI+blood-16:1/16:1-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.408	0.00058	no	no	no	up	up	no	HC
Isobutyric acid+stool	Insulin	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-16:1/16:1-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.408	0.00058	no	no	no	up	up	no	HC
Isobutyric acid+stool	Insulin	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-18:1/18:0-PS+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.408	0.00058	no	no	no	up	up	no	HC
Isobutyric acid+stool	Insulin	Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood-20:4-LPA+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.408	0.00058	no	no	no	up	up	no	HC
Kynurenic acid+stool	Insulin	Kynurenic acid+stool-nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.00058	dn	dn	no	up	up	no	HC
Kynurenic acid+stool	Insulin	Kynurenic acid+stool-UDCA+stool+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.00058	dn	dn	no	up	up	no	HC
Kynurenic acid+stool	Insulin	Kynurenic acid+stool-nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.00058	dn	dn	no	up	up	no	HC
Eggerthella	Insulin	Eggerthella+Clostridium-Cushing syndrome+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.912	0.00058	no	no	no	up	up	no	HC
Eggerthella	Insulin	Eggerthella+Clostridium-Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.912	0.00058	no	no	no	up	up	no	HC
Eggerthella	Insulin	Eggerthella+Bacteroides+Systemic lupus erythematosus-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.912	0.00058	no	no	no	up	up	no	HC
Eggerthella	Insulin	Eggerthella+Clostridium+Peroxisome-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.912	0.00058	no	no	no	up	up	no	HC
Anaerotruncus	Insulin	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Systemic lupus erythematosus-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.904	0.00058	no	no	no	up	up	no	HC
Anaerotruncus	Insulin	Anaerotruncus-Gemmiger-Tuberculosis+Systemic lupus erythematosus-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.904	0.00058	no	no	no	up	up	no	HC
Anaerotruncus	Insulin	Anaerotruncus-Gemmiger-L-Phenylalanine+stool-DCA+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.904	0.00058	no	no	no	up	up	no	HC
Anaerotruncus	Insulin	Anaerotruncus-Gemmiger-L-Tyrosine+stool-DCA+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.904	0.00058	no	no	no	up	up	no	HC
Anaerotruncus	Insulin	Anaerotruncus-Gemmiger-L-Tryptophan+stool-DCA+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.904	0.00058	no	no	no	up	up	no	HC
Anaerotruncus	Insulin	Anaerotruncus-Gemmiger-Staphylococcus aureus infection-Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.904	0.00058	no	no	no	up	up	no	HC
Anaerotruncus	Insulin	Anaerotruncus-Gemmiger-Tuberculosis-Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.904	0.00058	no	no	no	up	up	no	HC
Anaerostipes	Insulin	Anaerostipes-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.568	0.00058	no	no	no	up	up	no	HC
Isovaleric acid+stool	Insulin	Isovaleric acid+stool-nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.343	0.00058	no	no	no	up	up	no	HC
Isovaleric acid+stool	Insulin	Isovaleric acid+stool-nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_scfa	DM-associated hormones	0.343	0.00058	no	no	no	up	up	no	HC
Paraprevotella	Insulin	"Paraprevotella-Growth hormone synthesis, secretion and action+C-peptide+Insulin"	Indirect	Genus	DM-associated hormones	0.118	0.00058	no	no	no	up	up	no	HC
Paraprevotella	Insulin	Paraprevotella-GnRH signaling pathway+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.118	0.00058	no	no	no	up	up	no	HC
Paraprevotella	Insulin	Paraprevotella-Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.118	0.00058	no	no	no	up	up	no	HC
¦Ø-MCA+stool	Insulin	¦Ø-MCA+stool-Butyric acid+stool-L-Phenylalanine+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.00058	no	no	no	up	up	no	HC
¦Ø-MCA+stool	Insulin	¦Ø-MCA+stool-iso-DCA+stool-L-Tryptophan+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.00058	no	no	no	up	up	no	HC
¦Ø-MCA+stool	Insulin	¦Ø-MCA+stool-Butyric acid+stool-L-Tryptophan+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.00058	no	no	no	up	up	no	HC
Phenylacetic acid+stool	Insulin	Phenylacetic acid+stool-16:0/20:4-PI+blood-16:1/16:1-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.00058	no	no	no	up	up	no	HC
Phenylacetic acid+stool	Insulin	Phenylacetic acid+stool-16:0/18:2-PI+blood-16:1/16:1-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.00058	no	no	no	up	up	no	HC
Phenylacetic acid+stool	Insulin	Phenylacetic acid+stool-16:0/18:2-PI+blood-18:1/18:0-PS+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.00058	no	no	no	up	up	no	HC
Phenylacetic acid+stool	Insulin	Phenylacetic acid+stool+20:0+blood-20:4-LPA+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.00058	no	no	no	up	up	no	HC
Phenylacetic acid+stool	Insulin	Phenylacetic acid+stool+20:0+blood-20:3/18:0-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.00058	no	no	no	up	up	no	HC
Gemmiger	Insulin	Gemmiger-Staphylococcus aureus infection+Systemic lupus erythematosus-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.595	0.00058	no	no	no	up	up	no	HC
Gemmiger	Insulin	Gemmiger-Tuberculosis+Systemic lupus erythematosus-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.595	0.00058	no	no	no	up	up	no	HC
Gemmiger	Insulin	Gemmiger-L-Phenylalanine+stool-DCA+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.595	0.00058	no	no	no	up	up	no	HC
Gemmiger	Insulin	Gemmiger-L-Tyrosine+stool-DCA+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.595	0.00058	no	no	no	up	up	no	HC
Gemmiger	Insulin	Gemmiger-L-Tryptophan+stool-DCA+blood-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.595	0.00058	no	no	no	up	up	no	HC
Gemmiger	Insulin	Gemmiger-Staphylococcus aureus infection-Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.595	0.00058	no	no	no	up	up	no	HC
Gemmiger	Insulin	Gemmiger-Tuberculosis-Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.595	0.00058	no	no	no	up	up	no	HC
GDCA+stool	Insulin	GDCA+stool-16:0/18:2-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.00058	no	no	no	up	up	no	HC
L-Tyrosine+stool	Insulin	L-Tyrosine+stool-DCA+blood-C-peptide+Insulin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.00058	no	no	no	up	up	no	HC
CDCA+stool	Insulin	CDCA+stool+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.00058	no	no	no	up	up	no	HC
CDCA+stool	Insulin	CDCA+stool+GCA+stool+GCDCA+stool+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.663	0.00058	no	no	no	up	up	no	HC
CA+stool	Insulin	CA+stool+GCA+stool+GCDCA+stool+C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.00058	no	no	no	up	up	no	HC
UDCA+stool	Insulin	UDCA+stool+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.00058	no	no	no	up	up	no	HC
nutriCA+stool	Insulin	nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.00058	no	no	no	up	up	no	HC
nutriCA+stool	Insulin	nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide+Insulin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.00058	no	no	no	up	up	no	HC
acetic acid C2+blood	Insulin	acetic acid C2+blood-CA+blood+CDCA+blood+DCA+blood-C-peptide+Insulin	Indirect	serum_scfa	DM-associated hormones	0.000193	0.00058	up	dn	no	up	up	no	HC
Clostridium	Insulin	Clostridium-Cushing syndrome+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.925	0.00058	no	no	no	up	up	no	HC
Clostridium	Insulin	Clostridium-Chemical carcinogenesis - receptor activation+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.925	0.00058	no	no	no	up	up	no	HC
Clostridium	Insulin	Clostridium+Peroxisome-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.925	0.00058	no	no	no	up	up	no	HC
12-ketoDCA+blood	Insulin	12-ketoDCA+blood+DCA+blood-C-peptide+Insulin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.00058	no	no	no	up	up	no	HC
Butyricicoccus	Insulin	Butyricicoccus-Salivary secretion+Pancreatic secretion+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	HC
Butyricicoccus	Insulin	Butyricicoccus-Salivary secretion+Morphine addiction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	HC
Butyricicoccus	Insulin	Butyricicoccus-Hepatocellular carcinoma+GCDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	HC
Butyricicoccus	Insulin	Butyricicoccus-Focal adhesion+GCDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	HC
Butyricicoccus	Insulin	Butyricicoccus-Rap1 signaling pathway+GCDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	HC
Butyricicoccus	Insulin	Butyricicoccus-Leukocyte transendothelial migration+GCDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	HC
Butyricicoccus	Insulin	Butyricicoccus-Oxytocin signaling pathway+GCDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	HC
Butyricicoccus	Insulin	Butyricicoccus-Rap1 signaling pathway+Neutrophil extracellular trap formation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	HC
Butyricicoccus	Insulin	Butyricicoccus-Platelet activation+Melanogenesis+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	HC
Butyricicoccus	Insulin	Butyricicoccus-Focal adhesion+Gap junction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	HC
Butyricicoccus	Insulin	Butyricicoccus-Rap1 signaling pathway+Gap junction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.852	0.00058	no	no	no	up	up	no	HC
Wautersiella	Insulin	Wautersiella+Butyricicoccus-Salivary secretion+Pancreatic secretion+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.289	0.00058	no	no	no	up	up	no	HC
Wautersiella	Insulin	Wautersiella+Butyricicoccus-Salivary secretion+Morphine addiction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.289	0.00058	no	no	no	up	up	no	HC
Wautersiella	Insulin	Wautersiella+Butyricicoccus-Hepatocellular carcinoma+GCDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.289	0.00058	no	no	no	up	up	no	HC
Wautersiella	Insulin	Wautersiella+Butyricicoccus-Focal adhesion+GCDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.289	0.00058	no	no	no	up	up	no	HC
Wautersiella	Insulin	Wautersiella+Butyricicoccus-Rap1 signaling pathway+GCDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.289	0.00058	no	no	no	up	up	no	HC
Wautersiella	Insulin	Wautersiella+Butyricicoccus-Leukocyte transendothelial migration+GCDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.289	0.00058	no	no	no	up	up	no	HC
Wautersiella	Insulin	Wautersiella+Butyricicoccus-Oxytocin signaling pathway+GCDCA+stool+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.289	0.00058	no	no	no	up	up	no	HC
Wautersiella	Insulin	Wautersiella+Butyricicoccus-Rap1 signaling pathway+Neutrophil extracellular trap formation-C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.289	0.00058	no	no	no	up	up	no	HC
Wautersiella	Insulin	Wautersiella+Butyricicoccus-Platelet activation+Melanogenesis+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.289	0.00058	no	no	no	up	up	no	HC
Wautersiella	Insulin	Wautersiella+Butyricicoccus-Focal adhesion+Gap junction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.289	0.00058	no	no	no	up	up	no	HC
Wautersiella	Insulin	Wautersiella+Butyricicoccus-Rap1 signaling pathway+Gap junction+C-peptide+Insulin	Indirect	Genus	DM-associated hormones	0.289	0.00058	no	no	no	up	up	no	HC
Blautia	C-peptide	Blautia+Peroxisome-C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	HC
Blautia	C-peptide	Blautia-Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	HC
Blautia	C-peptide	Blautia-Cushing syndrome+C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	HC
Blautia	C-peptide	Blautia+Arginine and proline metabolism-C-peptide	Indirect	Genus	DM-associated hormones	1.36E-05	0.228	up	dn	dn	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-Phosphatidylinositol signaling system+Melanogenesis+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids-Melanogenesis+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-Phosphatidylinositol signaling system-Neutrophil extracellular trap formation-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids+Neutrophil extracellular trap formation-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-RNA degradation-Neutrophil extracellular trap formation-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Carbon metabolism+Neutrophil extracellular trap formation-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-mRNA surveillance pathway-Neutrophil extracellular trap formation-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-Phosphatidylinositol signaling system+Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids-Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-RNA degradation+Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Carbon metabolism-Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Glycolysis / Gluconeogenesis-Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-Pathways in cancer+Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-mRNA surveillance pathway+Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-Phosphatidylinositol signaling system+Aldosterone synthesis and secretion+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids-Aldosterone synthesis and secretion+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-RNA degradation+Aldosterone synthesis and secretion+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Carbon metabolism-Aldosterone synthesis and secretion+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Glycolysis / Gluconeogenesis-Aldosterone synthesis and secretion+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-mRNA surveillance pathway+Aldosterone synthesis and secretion+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-Phosphatidylinositol signaling system+Cushing syndrome+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids-Cushing syndrome+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Carbon metabolism-Cushing syndrome+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-mRNA surveillance pathway+Cushing syndrome+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids+Antigen processing and presentation-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-Phosphatidylinositol signaling system+Amphetamine addiction+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids-Amphetamine addiction+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-RNA degradation+Amphetamine addiction+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Carbon metabolism-Amphetamine addiction+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Glycolysis / Gluconeogenesis-Amphetamine addiction+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-mRNA surveillance pathway+Amphetamine addiction+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids+Fc gamma R-mediated phagocytosis-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-RNA degradation-Fc gamma R-mediated phagocytosis-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Carbon metabolism+Fc gamma R-mediated phagocytosis-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-mRNA surveillance pathway-Fc gamma R-mediated phagocytosis-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids-Endocrine resistance+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Carbon metabolism-Endocrine resistance+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Glycolysis / Gluconeogenesis-Endocrine resistance+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids+NOD-like receptor signaling pathway-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-RNA degradation-NOD-like receptor signaling pathway-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids-Long-term depression+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Carbon metabolism-Long-term depression+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Glycolysis / Gluconeogenesis-Long-term depression+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids-Morphine addiction+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-Phosphatidylinositol signaling system+Wnt signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids-Wnt signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-RNA degradation+Wnt signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Carbon metabolism-Wnt signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Glycolysis / Gluconeogenesis-Wnt signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-mRNA surveillance pathway+Wnt signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids+Osteoclast differentiation-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-Phosphatidylinositol signaling system+GnRH signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids-GnRH signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Carbon metabolism-GnRH signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Glycolysis / Gluconeogenesis-GnRH signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-mRNA surveillance pathway+GnRH signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids+Peroxisome-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-RNA degradation-Peroxisome-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-mRNA surveillance pathway-Peroxisome-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids-Pancreatic secretion+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-RNA degradation+Pancreatic secretion+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Carbon metabolism-Pancreatic secretion+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Glycolysis / Gluconeogenesis-Pancreatic secretion+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-mRNA surveillance pathway+Pancreatic secretion+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	"Parabacteroides-Phosphatidylinositol signaling system+Growth hormone synthesis, secretion and action+C-peptide"	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	"Parabacteroides+Biosynthesis of amino acids-Growth hormone synthesis, secretion and action+C-peptide"	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	"Parabacteroides+Carbon metabolism-Growth hormone synthesis, secretion and action+C-peptide"	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	"Parabacteroides+Glycolysis / Gluconeogenesis-Growth hormone synthesis, secretion and action+C-peptide"	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids+Systemic lupus erythematosus-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-Colorectal cancer-Systemic lupus erythematosus-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Carbon metabolism+Systemic lupus erythematosus-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-mRNA surveillance pathway-Systemic lupus erythematosus-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-Phosphatidylinositol signaling system+Inflammatory mediator regulation of TRP channels+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Biosynthesis of amino acids-Inflammatory mediator regulation of TRP channels+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-RNA degradation+Inflammatory mediator regulation of TRP channels+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides+Carbon metabolism-Inflammatory mediator regulation of TRP channels+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-mRNA surveillance pathway+Inflammatory mediator regulation of TRP channels+C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Parabacteroides	C-peptide	Parabacteroides-RNA degradation+Proteasome-C-peptide	Indirect	Genus	DM-associated hormones	4.19E-05	0.228	no	up	up	no	no	no	HC
Dorea	C-peptide	Dorea-Endocrine resistance+C-peptide	Indirect	Genus	DM-associated hormones	0.00362	0.228	up	no	dn	no	no	no	HC
Dorea	C-peptide	Dorea-Amphetamine addiction+C-peptide	Indirect	Genus	DM-associated hormones	0.00362	0.228	up	no	dn	no	no	no	HC
Dorea	C-peptide	Dorea-Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	0.00362	0.228	up	no	dn	no	no	no	HC
Dorea	C-peptide	"Dorea-Growth hormone synthesis, secretion and action+C-peptide"	Indirect	Genus	DM-associated hormones	0.00362	0.228	up	no	dn	no	no	no	HC
Dorea	C-peptide	Dorea-GnRH signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.00362	0.228	up	no	dn	no	no	no	HC
Faecalibacterium	C-peptide	Faecalibacterium-Staphylococcus aureus infection+Systemic lupus erythematosus-C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	HC
Faecalibacterium	C-peptide	Faecalibacterium+4-hydroxybenzoic acid+stool-ACA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	HC
Faecalibacterium	C-peptide	Faecalibacterium-Staphylococcus aureus infection-Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	0.0039	0.228	no	dn	dn	no	no	no	HC
Bacteroides	C-peptide	Bacteroides+Systemic lupus erythematosus-C-peptide	Indirect	Genus	DM-associated hormones	0.000267	0.228	dn	dn	up	no	no	no	HC
Propionic acid+stool	C-peptide	Propionic acid+stool+16:0/18:2-PI+blood-16:1/16:1-PC+blood-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0436	0.228	dn	no	up	no	no	no	HC
Propionic acid+stool	C-peptide	Propionic acid+stool-18:0/20:5-PC+blood+butyric acid C4+blood-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0436	0.228	dn	no	up	no	no	no	HC
Propionic acid+stool	C-peptide	Propionic acid+stool+16:0/18:2-PI+blood-18:1/18:0-PS+blood-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0436	0.228	dn	no	up	no	no	no	HC
[Ruminococcus]	C-peptide	[Ruminococcus]+Proteasome-C-peptide	Indirect	Genus	DM-associated hormones	0.0679	0.228	no	no	dn	no	no	no	HC
Acetic acid+stool	C-peptide	Acetic acid+stool-18:0/20:5-PC+blood+butyric acid C4+blood-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0656	0.228	dn	no	no	no	no	no	HC
Acetic acid+stool	C-peptide	Acetic acid+stool+16:0/18:2-PI+blood-16:1/16:1-PC+blood-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0656	0.228	dn	no	no	no	no	no	HC
Acetic acid+stool	C-peptide	Acetic acid+stool+Butyric acid+stool-L-Tryptophan+stool-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0656	0.228	dn	no	no	no	no	no	HC
Acetic acid+stool	C-peptide	Acetic acid+stool+Butyric acid+stool-L-Phenylalanine+stool-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0656	0.228	dn	no	no	no	no	no	HC
Acetic acid+stool	C-peptide	Acetic acid+stool+16:0/18:2-PI+blood-18:1/18:0-PS+blood-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.0656	0.228	dn	no	no	no	no	no	HC
Alistipes	C-peptide	Alistipes-GABAergic synapse-C-peptide	Indirect	Genus	DM-associated hormones	0.0114	0.228	no	up	no	no	no	no	HC
Alistipes	C-peptide	Alistipes-Peroxisome-C-peptide	Indirect	Genus	DM-associated hormones	0.0114	0.228	no	up	no	no	no	no	HC
Alistipes	C-peptide	Alistipes-NOD-like receptor signaling pathway-C-peptide	Indirect	Genus	DM-associated hormones	0.0114	0.228	no	up	no	no	no	no	HC
Alistipes	C-peptide	Alistipes-Olfactory transduction-C-peptide	Indirect	Genus	DM-associated hormones	0.0114	0.228	no	up	no	no	no	no	HC
Butyricimonas	C-peptide	Butyricimonas+Inflammatory mediator regulation of TRP channels+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	HC
Butyricimonas	C-peptide	Butyricimonas+Morphine addiction+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	HC
Butyricimonas	C-peptide	Butyricimonas+Long-term depression+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	HC
Butyricimonas	C-peptide	Butyricimonas+Pancreatic secretion+C-peptide	Indirect	Genus	DM-associated hormones	0.17	0.228	no	no	no	no	no	no	HC
Collinsella	C-peptide	Collinsella+18:0/18:0-PS+blood-DCA+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.128	0.228	no	no	no	no	no	no	HC
Collinsella	C-peptide	Collinsella+Porphyrin and chlorophyll metabolism+Gap junction+C-peptide	Indirect	Genus	DM-associated hormones	0.128	0.228	no	no	no	no	no	no	HC
Collinsella	C-peptide	"Collinsella+Glycine, serine and threonine metabolism+Gap junction+C-peptide"	Indirect	Genus	DM-associated hormones	0.128	0.228	no	no	no	no	no	no	HC
Collinsella	C-peptide	"Collinsella+Glycine, serine and threonine metabolism-Arginine and proline metabolism-C-peptide"	Indirect	Genus	DM-associated hormones	0.128	0.228	no	no	no	no	no	no	HC
Collinsella	C-peptide	Collinsella+Porphyrin and chlorophyll metabolism-NOD-like receptor signaling pathway-C-peptide	Indirect	Genus	DM-associated hormones	0.128	0.228	no	no	no	no	no	no	HC
Collinsella	C-peptide	"Collinsella+Glycine, serine and threonine metabolism-NOD-like receptor signaling pathway-C-peptide"	Indirect	Genus	DM-associated hormones	0.128	0.228	no	no	no	no	no	no	HC
Collinsella	C-peptide	Collinsella+Porphyrin and chlorophyll metabolism-Olfactory transduction-C-peptide	Indirect	Genus	DM-associated hormones	0.128	0.228	no	no	no	no	no	no	HC
Collinsella	C-peptide	"Collinsella+Glycine, serine and threonine metabolism-Olfactory transduction-C-peptide"	Indirect	Genus	DM-associated hormones	0.128	0.228	no	no	no	no	no	no	HC
Collinsella	C-peptide	Collinsella+Porphyrin and chlorophyll metabolism-Osteoclast differentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.128	0.228	no	no	no	no	no	no	HC
Collinsella	C-peptide	"Collinsella+Glycine, serine and threonine metabolism-Osteoclast differentiation-C-peptide"	Indirect	Genus	DM-associated hormones	0.128	0.228	no	no	no	no	no	no	HC
Collinsella	C-peptide	Collinsella+Porphyrin and chlorophyll metabolism-Fc gamma R-mediated phagocytosis-C-peptide	Indirect	Genus	DM-associated hormones	0.128	0.228	no	no	no	no	no	no	HC
Collinsella	C-peptide	"Collinsella+Glycine, serine and threonine metabolism-Fc gamma R-mediated phagocytosis-C-peptide"	Indirect	Genus	DM-associated hormones	0.128	0.228	no	no	no	no	no	no	HC
iso-DCA+stool	C-peptide	iso-DCA+stool-L-Tryptophan+stool-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.155	0.228	no	no	no	no	no	no	HC
LCA+stool	C-peptide	LCA+stool+16:0/18:2-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.314	0.228	no	no	no	no	no	no	HC
LCA+stool	C-peptide	LCA+stool+16:0/18:1-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.314	0.228	no	no	no	no	no	no	HC
LCA+stool	C-peptide	LCA+stool+16:0/18:1-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.314	0.228	no	no	no	no	no	no	HC
LCA+stool	C-peptide	LCA+stool+18:0/16:0-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.314	0.228	no	no	no	no	no	no	HC
LCA+stool	C-peptide	LCA+stool+16:0/18:1-PC+blood-CDCA+blood+DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.314	0.228	no	no	no	no	no	no	HC
LCA+stool	C-peptide	LCA+stool+18:0/16:0-PC+blood-CDCA+blood+DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.314	0.228	no	no	no	no	no	no	HC
LCA+stool	C-peptide	LCA+stool-nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.314	0.228	no	no	no	no	no	no	HC
LCA+stool	C-peptide	LCA+stool-nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.314	0.228	no	no	no	no	no	no	HC
Akkermansia	C-peptide	Akkermansia-Wnt signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.23	0.228	no	no	no	no	no	no	HC
Akkermansia	C-peptide	Akkermansia+Systemic lupus erythematosus-C-peptide	Indirect	Genus	DM-associated hormones	0.23	0.228	no	no	no	no	no	no	HC
Bifidobacterium	C-peptide	Bifidobacterium-DCA+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.105	0.228	no	dn	no	no	no	no	HC
Ruminococcus	C-peptide	Ruminococcus+C-peptide	Direct	Genus	DM-associated hormones	0.335	0.228	no	no	no	no	no	no	HC
[Prevotella]	C-peptide	"[Prevotella]-Growth hormone synthesis, secretion and action+C-peptide"	Indirect	Genus	DM-associated hormones	0.367	0.228	no	no	no	no	no	no	HC
[Prevotella]	C-peptide	[Prevotella]-Aldosterone synthesis and secretion+C-peptide	Indirect	Genus	DM-associated hormones	0.367	0.228	no	no	no	no	no	no	HC
[Prevotella]	C-peptide	[Prevotella]-GnRH signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.367	0.228	no	no	no	no	no	no	HC
[Prevotella]	C-peptide	[Prevotella]-ACA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.367	0.228	no	no	no	no	no	no	HC
[Prevotella]	C-peptide	[Prevotella]-Gap junction+C-peptide	Indirect	Genus	DM-associated hormones	0.367	0.228	no	no	no	no	no	no	HC
[Prevotella]	C-peptide	[Prevotella]-Morphine addiction+C-peptide	Indirect	Genus	DM-associated hormones	0.367	0.228	no	no	no	no	no	no	HC
DCA+stool	C-peptide	DCA+stool-L-Tyrosine+stool-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.195	0.228	no	no	no	no	no	no	HC
DCA+stool	C-peptide	DCA+stool-L-Phenylalanine+stool-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.195	0.228	no	no	no	no	no	no	HC
DCA+stool	C-peptide	DCA+stool-L-Tryptophan+stool-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.195	0.228	no	no	no	no	no	no	HC
Butyric acid+stool	C-peptide	Butyric acid+stool-L-Tryptophan+stool-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.102	0.228	dn	no	no	no	no	no	HC
Butyric acid+stool	C-peptide	Butyric acid+stool-L-Phenylalanine+stool-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.102	0.228	dn	no	no	no	no	no	HC
4-hydroxybenzoic acid+stool	C-peptide	4-hydroxybenzoic acid+stool-ACA+stool+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.228	no	dn	no	no	no	no	HC
ACA+stool	C-peptide	ACA+stool+C-peptide	Direct	stool_bileacids	DM-associated hormones	0.417	0.228	no	no	no	no	no	no	HC
CDCA+blood	C-peptide	CDCA+blood+DCA+blood-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.506	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-Lysosome+Systemic lupus erythematosus-C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-B cell receptor signaling pathway-Melanogenesis+C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-IL-17 signaling pathway-Melanogenesis+C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella+Estrogen signaling pathway+Melanogenesis+C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-IL-17 signaling pathway-Amphetamine addiction+C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella+Estrogen signaling pathway+Amphetamine addiction+C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-Lysosome-Amphetamine addiction+C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-IL-17 signaling pathway-Cushing syndrome+C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-Lysosome-Cushing syndrome+C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-IL-17 signaling pathway+GABAergic synapse-C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-Lysosome+GABAergic synapse-C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-IL-17 signaling pathway+Fc gamma R-mediated phagocytosis-C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-Lysosome+Fc gamma R-mediated phagocytosis-C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-IL-17 signaling pathway+Olfactory transduction-C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-Lysosome+Olfactory transduction-C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella+12-ketoDCA+blood+DCA+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-20:3/18:0-PC+blood-DCA+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-L-Tryptophan+stool-DCA+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-16:1/16:1-PC+blood-DCA+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-Lysosome+Osteoclast differentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella+Estrogen signaling pathway+Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-Lysosome+NOD-like receptor signaling pathway-C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
Prevotella	C-peptide	Prevotella-Lysosome+Neutrophil extracellular trap formation-C-peptide	Indirect	Genus	DM-associated hormones	0.287	0.228	no	no	no	no	no	no	HC
HCA+stool	C-peptide	HCA+stool+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.155	0.228	no	no	no	no	no	no	HC
HCA+stool	C-peptide	HCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.155	0.228	no	no	no	no	no	no	HC
Roseburia	C-peptide	Roseburia-ACA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.495	0.228	no	no	no	no	no	no	HC
12-ketoDCA+stool	C-peptide	12-ketoDCA+stool-CA+stool+GCA+stool+GCDCA+stool+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.505	0.228	no	no	no	no	no	no	HC
12-ketoDCA+stool	C-peptide	12-ketoDCA+stool-CDCA+stool+GCA+stool+GCDCA+stool+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.505	0.228	no	no	no	no	no	no	HC
12-ketoDCA+stool	C-peptide	12-ketoDCA+stool-15-HETE+blood-18:0/18:0-PS+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.505	0.228	no	no	no	no	no	no	HC
12-ketoDCA+stool	C-peptide	12-ketoDCA+stool-15-HETE+blood+butyric acid C4+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.505	0.228	no	no	no	no	no	no	HC
12-ketoDCA+stool	C-peptide	12-ketoDCA+stool-CDCA+stool+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.505	0.228	no	no	no	no	no	no	HC
12-ketoDCA+stool	C-peptide	12-ketoDCA+stool+DCA+stool-L-Tryptophan+stool-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.505	0.228	no	no	no	no	no	no	HC
12-ketoDCA+stool	C-peptide	12-ketoDCA+stool+DCA+stool-L-Phenylalanine+stool-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.505	0.228	no	no	no	no	no	no	HC
12-ketoDCA+stool	C-peptide	12-ketoDCA+stool+DCA+stool-L-Tyrosine+stool-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.505	0.228	no	no	no	no	no	no	HC
L-Tryptophan+stool	C-peptide	L-Tryptophan+stool-DCA+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.228	no	no	no	no	no	no	HC
CA+blood	C-peptide	CA+blood+CDCA+blood+DCA+blood-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.606	0.228	no	no	no	no	no	no	HC
GUDCA+stool	C-peptide	GUDCA+stool+L-Tryptophan+stool-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.228	no	dn	no	no	no	no	HC
L-Phenylalanine+stool	C-peptide	L-Phenylalanine+stool-DCA+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.398	0.228	no	no	no	no	no	no	HC
butyric acid C4+blood	C-peptide	butyric acid C4+blood-DCA+blood-C-peptide	Indirect	serum_scfa	DM-associated hormones	0.407	0.228	no	no	no	no	no	no	HC
GCA+stool	C-peptide	GCA+stool+GCDCA+stool+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.0809	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus-Lysosome-Amphetamine addiction+C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus+Lachnospira-Herpes simplex virus 1 infection-C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus+Lachnospira+GCDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus+Ribosome biogenesis in eukaryotes-GCDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus-Lysosome-Cushing syndrome+C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus+Lachnospira-Proteasome-C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus-Lysosome+Systemic lupus erythematosus-C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus-Influenza A+Systemic lupus erythematosus-C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus-Lysosome+Fc gamma R-mediated phagocytosis-C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus+Ribosome biogenesis in eukaryotes-Fc gamma R-mediated phagocytosis-C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus-Lysosome+GABAergic synapse-C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus-Lysosome+Neutrophil extracellular trap formation-C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus+Ribosome biogenesis in eukaryotes-Neutrophil extracellular trap formation-C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus-Lysosome+Osteoclast differentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus+Ribosome biogenesis in eukaryotes-Osteoclast differentiation-C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus-Lysosome+NOD-like receptor signaling pathway-C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus-Lysosome+Olfactory transduction-C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Coprococcus	C-peptide	Coprococcus+Primary immunodeficiency-ACA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.612	0.228	no	no	no	no	no	no	HC
Oscillospira	C-peptide	Oscillospira+C-peptide	Direct	Genus	DM-associated hormones	0.62	0.228	no	no	no	no	no	no	HC
iso-LCA+stool	C-peptide	iso-LCA+stool-16:0/18:3-PC+blood+20:3/18:0-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.72	0.228	no	no	no	no	no	no	HC
iso-LCA+stool	C-peptide	iso-LCA+stool-nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.72	0.228	no	no	no	no	no	no	HC
iso-LCA+stool	C-peptide	iso-LCA+stool-16:0/18:3-PC+blood+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.72	0.228	no	no	no	no	no	no	HC
iso-LCA+stool	C-peptide	iso-LCA+stool-nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.72	0.228	no	no	no	no	no	no	HC
iso-LCA+stool	C-peptide	iso-LCA+stool-UDCA+stool+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.72	0.228	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	C-peptide	2-methyl-butyric acid m-C4+blood+butyric acid C4+blood-DCA+blood-C-peptide	Indirect	serum_scfa	DM-associated hormones	0.262	0.228	no	no	no	no	no	no	HC
DCA+blood	C-peptide	DCA+blood-C-peptide	Direct	serum_bileacids	DM-associated hormones	0.122	0.228	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	C-peptide	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/22:6-PC+blood-20:2/18:3-PE+blood-DCA+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.228	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	C-peptide	3-(3-Hydroxyphenyl)propanoic acid+stool+14:0+blood+16:0+blood-DCA+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.228	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	C-peptide	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/22:6-PC+blood-20:0/20:4-PE+blood-DCA+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.228	no	no	no	no	no	no	HC
GLCA+stool	C-peptide	GLCA+stool-LCA+stool-nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.617	0.228	no	no	no	no	no	no	HC
GLCA+stool	C-peptide	GLCA+stool-iso-LCA+stool-nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.617	0.228	no	no	no	no	no	no	HC
GLCA+stool	C-peptide	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+20:3/18:0-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.617	0.228	no	no	no	no	no	no	HC
GLCA+stool	C-peptide	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-CDCA+blood+DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.617	0.228	no	no	no	no	no	no	HC
GLCA+stool	C-peptide	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-CDCA+blood+DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.617	0.228	no	no	no	no	no	no	HC
GLCA+stool	C-peptide	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.617	0.228	no	no	no	no	no	no	HC
GLCA+stool	C-peptide	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.617	0.228	no	no	no	no	no	no	HC
GLCA+stool	C-peptide	GLCA+stool-iso-LCA+stool-UDCA+stool+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.617	0.228	no	no	no	no	no	no	HC
GLCA+stool	C-peptide	GLCA+stool-LCA+stool-nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.617	0.228	no	no	no	no	no	no	HC
GLCA+stool	C-peptide	GLCA+stool-iso-LCA+stool-nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.617	0.228	no	no	no	no	no	no	HC
GLCA+stool	C-peptide	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.617	0.228	no	no	no	no	no	no	HC
GLCA+stool	C-peptide	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.617	0.228	no	no	no	no	no	no	HC
GLCA+stool	C-peptide	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.617	0.228	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	C-peptide	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-DCA+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.228	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	C-peptide	Indole-3-Acetic acid+stool+L-Tryptophan+stool-DCA+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.228	no	no	no	no	no	no	HC
TCA+stool	C-peptide	TCA+stool+16:0/20:4-PI+blood-16:1/16:1-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.458	0.228	no	no	no	no	no	no	HC
TCA+stool	C-peptide	TCA+stool-16:0/18:1-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.458	0.228	no	no	no	no	no	no	HC
TCA+stool	C-peptide	TCA+stool-16:0/18:2-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.458	0.228	no	no	no	no	no	no	HC
TCA+stool	C-peptide	TCA+stool-16:0/18:1-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.458	0.228	no	no	no	no	no	no	HC
TCA+stool	C-peptide	TCA+stool-18:0/16:0-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.458	0.228	no	no	no	no	no	no	HC
TCA+stool	C-peptide	TCA+stool-18:1/18:0-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.458	0.228	no	no	no	no	no	no	HC
TCA+stool	C-peptide	TCA+stool-16:0/18:1-PC+blood-CDCA+blood+DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.458	0.228	no	no	no	no	no	no	HC
TCA+stool	C-peptide	TCA+stool-18:0/16:0-PC+blood-CDCA+blood+DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.458	0.228	no	no	no	no	no	no	HC
TCA+stool	C-peptide	TCA+stool-18:1/18:1-PC+blood-20:4/18:0-PE+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.458	0.228	no	no	no	no	no	no	HC
TCA+stool	C-peptide	TCA+stool-20:0+blood-20:4-LPA+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.458	0.228	no	no	no	no	no	no	HC
TCA+stool	C-peptide	TCA+stool-20:0+blood-20:3/18:0-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.458	0.228	no	no	no	no	no	no	HC
HDCA+stool	C-peptide	HDCA+stool+16:0/18:1-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.176	0.228	no	no	no	no	no	no	HC
HDCA+stool	C-peptide	HDCA+stool+18:0/16:0-PC+blood+18:1/18:0-PS+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.176	0.228	no	no	no	no	no	no	HC
HDCA+stool	C-peptide	HDCA+stool+16:0/20:4-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.176	0.228	no	no	no	no	no	no	HC
HDCA+stool	C-peptide	HDCA+stool+16:0/18:1-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.176	0.228	no	no	no	no	no	no	HC
HDCA+stool	C-peptide	HDCA+stool+16:0/18:1-PC+blood-CDCA+blood+DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.176	0.228	no	no	no	no	no	no	HC
HDCA+stool	C-peptide	HDCA+stool+18:0/16:0-PC+blood-CDCA+blood+DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.176	0.228	no	no	no	no	no	no	HC
HDCA+stool	C-peptide	HDCA+stool+iso-DCA+stool-L-Tryptophan+stool-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.176	0.228	no	no	no	no	no	no	HC
HDCA+stool	C-peptide	HDCA+stool-16:0/18:3-PC+blood+20:3/18:0-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.176	0.228	no	no	no	no	no	no	HC
HDCA+stool	C-peptide	HDCA+stool-nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.176	0.228	no	no	no	no	no	no	HC
HDCA+stool	C-peptide	HDCA+stool-16:0/18:3-PC+blood+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.176	0.228	no	no	no	no	no	no	HC
HDCA+stool	C-peptide	HDCA+stool-nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.176	0.228	no	no	no	no	no	no	HC
Lachnospira	C-peptide	Lachnospira-Proteasome-C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	HC
Lachnospira	C-peptide	Lachnospira+GCDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	HC
Lachnospira	C-peptide	Lachnospira-Herpes simplex virus 1 infection-C-peptide	Indirect	Genus	DM-associated hormones	0.279	0.228	no	no	no	no	no	no	HC
GCDCA+stool	C-peptide	GCDCA+stool+C-peptide	Direct	stool_bileacids	DM-associated hormones	0.0471	0.228	no	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	C-peptide	5-Hydroxytryptamine+stool+GCDCA+stool+C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.228	dn	dn	no	no	no	no	HC
Odoribacter	C-peptide	Odoribacter-C-peptide	Direct	Genus	DM-associated hormones	0.798	0.228	no	no	no	no	no	no	HC
Isobutyric acid+stool	C-peptide	Isobutyric acid+stool+Isovaleric acid+stool-nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.408	0.228	no	no	no	no	no	no	HC
Isobutyric acid+stool	C-peptide	Isobutyric acid+stool+Isovaleric acid+stool-nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.408	0.228	no	no	no	no	no	no	HC
Isobutyric acid+stool	C-peptide	Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood-20:3/18:0-PC+blood-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.408	0.228	no	no	no	no	no	no	HC
Isobutyric acid+stool	C-peptide	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/20:4-PI+blood-16:1/16:1-PC+blood-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.408	0.228	no	no	no	no	no	no	HC
Isobutyric acid+stool	C-peptide	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-16:1/16:1-PC+blood-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.408	0.228	no	no	no	no	no	no	HC
Isobutyric acid+stool	C-peptide	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-18:1/18:0-PS+blood-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.408	0.228	no	no	no	no	no	no	HC
Isobutyric acid+stool	C-peptide	Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood-20:4-LPA+blood-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.408	0.228	no	no	no	no	no	no	HC
Kynurenic acid+stool	C-peptide	Kynurenic acid+stool-nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.228	dn	dn	no	no	no	no	HC
Kynurenic acid+stool	C-peptide	Kynurenic acid+stool-UDCA+stool+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.228	dn	dn	no	no	no	no	HC
Kynurenic acid+stool	C-peptide	Kynurenic acid+stool-nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.228	dn	dn	no	no	no	no	HC
Eggerthella	C-peptide	Eggerthella+Clostridium-Cushing syndrome+C-peptide	Indirect	Genus	DM-associated hormones	0.912	0.228	no	no	no	no	no	no	HC
Eggerthella	C-peptide	Eggerthella+Clostridium-Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	0.912	0.228	no	no	no	no	no	no	HC
Eggerthella	C-peptide	Eggerthella+Bacteroides+Systemic lupus erythematosus-C-peptide	Indirect	Genus	DM-associated hormones	0.912	0.228	no	no	no	no	no	no	HC
Eggerthella	C-peptide	Eggerthella+Clostridium+Peroxisome-C-peptide	Indirect	Genus	DM-associated hormones	0.912	0.228	no	no	no	no	no	no	HC
Anaerotruncus	C-peptide	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Systemic lupus erythematosus-C-peptide	Indirect	Genus	DM-associated hormones	0.904	0.228	no	no	no	no	no	no	HC
Anaerotruncus	C-peptide	Anaerotruncus-Gemmiger-Tuberculosis+Systemic lupus erythematosus-C-peptide	Indirect	Genus	DM-associated hormones	0.904	0.228	no	no	no	no	no	no	HC
Anaerotruncus	C-peptide	Anaerotruncus-Gemmiger-L-Phenylalanine+stool-DCA+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.904	0.228	no	no	no	no	no	no	HC
Anaerotruncus	C-peptide	Anaerotruncus-Gemmiger-L-Tyrosine+stool-DCA+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.904	0.228	no	no	no	no	no	no	HC
Anaerotruncus	C-peptide	Anaerotruncus-Gemmiger-L-Tryptophan+stool-DCA+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.904	0.228	no	no	no	no	no	no	HC
Anaerotruncus	C-peptide	Anaerotruncus-Gemmiger-Staphylococcus aureus infection-Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	0.904	0.228	no	no	no	no	no	no	HC
Anaerotruncus	C-peptide	Anaerotruncus-Gemmiger-Tuberculosis-Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	0.904	0.228	no	no	no	no	no	no	HC
Anaerostipes	C-peptide	Anaerostipes-C-peptide	Direct	Genus	DM-associated hormones	0.568	0.228	no	no	no	no	no	no	HC
Isovaleric acid+stool	C-peptide	Isovaleric acid+stool-nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.343	0.228	no	no	no	no	no	no	HC
Isovaleric acid+stool	C-peptide	Isovaleric acid+stool-nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide	Indirect	stool_scfa	DM-associated hormones	0.343	0.228	no	no	no	no	no	no	HC
Paraprevotella	C-peptide	"Paraprevotella-Growth hormone synthesis, secretion and action+C-peptide"	Indirect	Genus	DM-associated hormones	0.118	0.228	no	no	no	no	no	no	HC
Paraprevotella	C-peptide	Paraprevotella-GnRH signaling pathway+C-peptide	Indirect	Genus	DM-associated hormones	0.118	0.228	no	no	no	no	no	no	HC
Paraprevotella	C-peptide	Paraprevotella-Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	0.118	0.228	no	no	no	no	no	no	HC
¦Ø-MCA+stool	C-peptide	¦Ø-MCA+stool-Butyric acid+stool-L-Phenylalanine+stool-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.919	0.228	no	no	no	no	no	no	HC
¦Ø-MCA+stool	C-peptide	¦Ø-MCA+stool-iso-DCA+stool-L-Tryptophan+stool-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.919	0.228	no	no	no	no	no	no	HC
¦Ø-MCA+stool	C-peptide	¦Ø-MCA+stool-Butyric acid+stool-L-Tryptophan+stool-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.919	0.228	no	no	no	no	no	no	HC
Phenylacetic acid+stool	C-peptide	Phenylacetic acid+stool-16:0/20:4-PI+blood-16:1/16:1-PC+blood-DCA+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.228	no	no	no	no	no	no	HC
Phenylacetic acid+stool	C-peptide	Phenylacetic acid+stool-16:0/18:2-PI+blood-16:1/16:1-PC+blood-DCA+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.228	no	no	no	no	no	no	HC
Phenylacetic acid+stool	C-peptide	Phenylacetic acid+stool-16:0/18:2-PI+blood-18:1/18:0-PS+blood-DCA+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.228	no	no	no	no	no	no	HC
Phenylacetic acid+stool	C-peptide	Phenylacetic acid+stool+20:0+blood-20:4-LPA+blood-DCA+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.228	no	no	no	no	no	no	HC
Phenylacetic acid+stool	C-peptide	Phenylacetic acid+stool+20:0+blood-20:3/18:0-PC+blood-DCA+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.785	0.228	no	no	no	no	no	no	HC
Gemmiger	C-peptide	Gemmiger-Staphylococcus aureus infection+Systemic lupus erythematosus-C-peptide	Indirect	Genus	DM-associated hormones	0.595	0.228	no	no	no	no	no	no	HC
Gemmiger	C-peptide	Gemmiger-Tuberculosis+Systemic lupus erythematosus-C-peptide	Indirect	Genus	DM-associated hormones	0.595	0.228	no	no	no	no	no	no	HC
Gemmiger	C-peptide	Gemmiger-L-Phenylalanine+stool-DCA+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.595	0.228	no	no	no	no	no	no	HC
Gemmiger	C-peptide	Gemmiger-L-Tyrosine+stool-DCA+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.595	0.228	no	no	no	no	no	no	HC
Gemmiger	C-peptide	Gemmiger-L-Tryptophan+stool-DCA+blood-C-peptide	Indirect	Genus	DM-associated hormones	0.595	0.228	no	no	no	no	no	no	HC
Gemmiger	C-peptide	Gemmiger-Staphylococcus aureus infection-Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	0.595	0.228	no	no	no	no	no	no	HC
Gemmiger	C-peptide	Gemmiger-Tuberculosis-Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	0.595	0.228	no	no	no	no	no	no	HC
GDCA+stool	C-peptide	GDCA+stool-16:0/18:2-PC+blood+16:1/16:1-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.656	0.228	no	no	no	no	no	no	HC
L-Tyrosine+stool	C-peptide	L-Tyrosine+stool-DCA+blood-C-peptide	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.228	no	no	no	no	no	no	HC
CDCA+stool	C-peptide	CDCA+stool+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.663	0.228	no	no	no	no	no	no	HC
CDCA+stool	C-peptide	CDCA+stool+GCA+stool+GCDCA+stool+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.663	0.228	no	no	no	no	no	no	HC
CA+stool	C-peptide	CA+stool+GCA+stool+GCDCA+stool+C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.827	0.228	no	no	no	no	no	no	HC
UDCA+stool	C-peptide	UDCA+stool+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.266	0.228	no	no	no	no	no	no	HC
nutriCA+stool	C-peptide	nutriCA+stool+18:3n3+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.481	0.228	no	no	no	no	no	no	HC
nutriCA+stool	C-peptide	nutriCA+stool+20:3/18:0-PC+blood-DCA+blood-C-peptide	Indirect	stool_bileacids	DM-associated hormones	0.481	0.228	no	no	no	no	no	no	HC
acetic acid C2+blood	C-peptide	acetic acid C2+blood-CA+blood+CDCA+blood+DCA+blood-C-peptide	Indirect	serum_scfa	DM-associated hormones	0.000193	0.228	up	dn	no	no	no	no	HC
Clostridium	C-peptide	Clostridium-Cushing syndrome+C-peptide	Indirect	Genus	DM-associated hormones	0.925	0.228	no	no	no	no	no	no	HC
Clostridium	C-peptide	Clostridium-Chemical carcinogenesis - receptor activation+C-peptide	Indirect	Genus	DM-associated hormones	0.925	0.228	no	no	no	no	no	no	HC
Clostridium	C-peptide	Clostridium+Peroxisome-C-peptide	Indirect	Genus	DM-associated hormones	0.925	0.228	no	no	no	no	no	no	HC
12-ketoDCA+blood	C-peptide	12-ketoDCA+blood+DCA+blood-C-peptide	Indirect	serum_bileacids	DM-associated hormones	0.517	0.228	no	no	no	no	no	no	HC
Butyricicoccus	C-peptide	Butyricicoccus-Salivary secretion+Pancreatic secretion+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	HC
Butyricicoccus	C-peptide	Butyricicoccus-Salivary secretion+Morphine addiction+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	HC
Butyricicoccus	C-peptide	Butyricicoccus-Hepatocellular carcinoma+GCDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	HC
Butyricicoccus	C-peptide	Butyricicoccus-Focal adhesion+GCDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	HC
Butyricicoccus	C-peptide	Butyricicoccus-Rap1 signaling pathway+GCDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	HC
Butyricicoccus	C-peptide	Butyricicoccus-Leukocyte transendothelial migration+GCDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	HC
Butyricicoccus	C-peptide	Butyricicoccus-Oxytocin signaling pathway+GCDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	HC
Butyricicoccus	C-peptide	Butyricicoccus-Rap1 signaling pathway+Neutrophil extracellular trap formation-C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	HC
Butyricicoccus	C-peptide	Butyricicoccus-Platelet activation+Melanogenesis+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	HC
Butyricicoccus	C-peptide	Butyricicoccus-Focal adhesion+Gap junction+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	HC
Butyricicoccus	C-peptide	Butyricicoccus-Rap1 signaling pathway+Gap junction+C-peptide	Indirect	Genus	DM-associated hormones	0.852	0.228	no	no	no	no	no	no	HC
Wautersiella	C-peptide	Wautersiella+Butyricicoccus-Salivary secretion+Pancreatic secretion+C-peptide	Indirect	Genus	DM-associated hormones	0.289	0.228	no	no	no	no	no	no	HC
Wautersiella	C-peptide	Wautersiella+Butyricicoccus-Salivary secretion+Morphine addiction+C-peptide	Indirect	Genus	DM-associated hormones	0.289	0.228	no	no	no	no	no	no	HC
Wautersiella	C-peptide	Wautersiella+Butyricicoccus-Hepatocellular carcinoma+GCDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.289	0.228	no	no	no	no	no	no	HC
Wautersiella	C-peptide	Wautersiella+Butyricicoccus-Focal adhesion+GCDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.289	0.228	no	no	no	no	no	no	HC
Wautersiella	C-peptide	Wautersiella+Butyricicoccus-Rap1 signaling pathway+GCDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.289	0.228	no	no	no	no	no	no	HC
Wautersiella	C-peptide	Wautersiella+Butyricicoccus-Leukocyte transendothelial migration+GCDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.289	0.228	no	no	no	no	no	no	HC
Wautersiella	C-peptide	Wautersiella+Butyricicoccus-Oxytocin signaling pathway+GCDCA+stool+C-peptide	Indirect	Genus	DM-associated hormones	0.289	0.228	no	no	no	no	no	no	HC
Wautersiella	C-peptide	Wautersiella+Butyricicoccus-Rap1 signaling pathway+Neutrophil extracellular trap formation-C-peptide	Indirect	Genus	DM-associated hormones	0.289	0.228	no	no	no	no	no	no	HC
Wautersiella	C-peptide	Wautersiella+Butyricicoccus-Platelet activation+Melanogenesis+C-peptide	Indirect	Genus	DM-associated hormones	0.289	0.228	no	no	no	no	no	no	HC
Wautersiella	C-peptide	Wautersiella+Butyricicoccus-Focal adhesion+Gap junction+C-peptide	Indirect	Genus	DM-associated hormones	0.289	0.228	no	no	no	no	no	no	HC
Wautersiella	C-peptide	Wautersiella+Butyricicoccus-Rap1 signaling pathway+Gap junction+C-peptide	Indirect	Genus	DM-associated hormones	0.289	0.228	no	no	no	no	no	no	HC
Blautia	FGF basic	Blautia+P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	1.36E-05	0.65	up	dn	dn	no	no	no	HC
Parabacteroides	FGF basic	Parabacteroides+Biosynthesis of amino acids-FGF basic	Indirect	Genus	serum_cytokines	4.19E-05	0.65	no	up	up	no	no	no	HC
Parabacteroides	FGF basic	Parabacteroides-RNA degradation+FGF basic	Indirect	Genus	serum_cytokines	4.19E-05	0.65	no	up	up	no	no	no	HC
Parabacteroides	FGF basic	Parabacteroides-mRNA surveillance pathway+FGF basic	Indirect	Genus	serum_cytokines	4.19E-05	0.65	no	up	up	no	no	no	HC
Dorea	FGF basic	Dorea-VEGF signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Fc epsilon RI signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-18:2-LPC+blood+20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Endocrine resistance+Huntington disease+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Endocrine resistance+L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Chemical carcinogenesis - receptor activation+L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	"Dorea-Growth hormone synthesis, secretion and action+L-Homocystine+blood+FGF basic"	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Endocrine resistance+mRNA surveillance pathway+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Endocrine resistance+Non-alcoholic fatty liver disease+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-GnRH signaling pathway+Non-alcoholic fatty liver disease+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Endocrine resistance+Parkinson disease+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-GnRH signaling pathway+Parkinson disease+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Endocrine resistance+Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Endocrine resistance+RNA degradation+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Endocrine resistance+Thermogenesis+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Thyroid hormone signaling pathway+Viral myocarditis-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Chemical carcinogenesis - receptor activation-Viral myocarditis-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-16:0-LPC+blood+AA+blood-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Amphetamine addiction-Human papillomavirus infection-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Amphetamine addiction-Autoimmune thyroid disease-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Chemical carcinogenesis - receptor activation-Autoimmune thyroid disease-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-16:0-LPC+blood+TXB2+blood-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Amphetamine addiction-Allograft rejection-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Chemical carcinogenesis - receptor activation-Allograft rejection-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Amphetamine addiction-Graft-versus-host disease-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Chemical carcinogenesis - receptor activation-Graft-versus-host disease-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea+Legionellosis-Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Amphetamine addiction+Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Chemical carcinogenesis - receptor activation+Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Amphetamine addiction-Viral carcinogenesis-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Endocrine resistance+Amyotrophic lateral sclerosis+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-GnRH signaling pathway+Amyotrophic lateral sclerosis+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Chemical carcinogenesis - receptor activation-P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Dorea	FGF basic	Dorea-Endocrine resistance+Alzheimer disease+FGF basic	Indirect	Genus	serum_cytokines	0.00362	0.65	up	no	dn	no	no	no	HC
Faecalibacterium	FGF basic	Faecalibacterium+Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0039	0.65	no	dn	dn	no	no	no	HC
Faecalibacterium	FGF basic	Faecalibacterium-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic	Indirect	Genus	serum_cytokines	0.0039	0.65	no	dn	dn	no	no	no	HC
Faecalibacterium	FGF basic	Faecalibacterium-Staphylococcus aureus infection+Viral myocarditis-FGF basic	Indirect	Genus	serum_cytokines	0.0039	0.65	no	dn	dn	no	no	no	HC
Faecalibacterium	FGF basic	Faecalibacterium-Staphylococcus aureus infection+Allograft rejection-FGF basic	Indirect	Genus	serum_cytokines	0.0039	0.65	no	dn	dn	no	no	no	HC
Faecalibacterium	FGF basic	Faecalibacterium-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic	Indirect	Genus	serum_cytokines	0.0039	0.65	no	dn	dn	no	no	no	HC
Faecalibacterium	FGF basic	Faecalibacterium+4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0039	0.65	no	dn	dn	no	no	no	HC
Faecalibacterium	FGF basic	Faecalibacterium-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.0039	0.65	no	dn	dn	no	no	no	HC
TUDCA+blood	FGF basic	TUDCA+blood-L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.0282	0.65	no	no	dn	no	no	no	HC
TUDCA+blood	FGF basic	TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.0282	0.65	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	FGF basic	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_scfa	serum_cytokines	0.0458	0.65	no	no	dn	no	no	no	HC
Bacteroides	FGF basic	Bacteroides-FGF basic	Direct	Genus	serum_cytokines	0.000267	0.65	dn	dn	up	no	no	no	HC
Propionic acid+stool	FGF basic	Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_scfa	serum_cytokines	0.0436	0.65	dn	no	up	no	no	no	HC
Propionic acid+stool	FGF basic	Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_scfa	serum_cytokines	0.0436	0.65	dn	no	up	no	no	no	HC
Propionic acid+stool	FGF basic	Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic	Indirect	stool_scfa	serum_cytokines	0.0436	0.65	dn	no	up	no	no	no	HC
Propionic acid+stool	FGF basic	Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_scfa	serum_cytokines	0.0436	0.65	dn	no	up	no	no	no	HC
Propionic acid+stool	FGF basic	Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic	Indirect	stool_scfa	serum_cytokines	0.0436	0.65	dn	no	up	no	no	no	HC
[Ruminococcus]	FGF basic	[Ruminococcus]+nutriCA+stool-L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	HC
[Ruminococcus]	FGF basic	[Ruminococcus]+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	HC
[Ruminococcus]	FGF basic	[Ruminococcus]-Hypotaurine+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.0679	0.65	no	no	dn	no	no	no	HC
GUDCA+blood	FGF basic	GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.0766	0.65	no	no	dn	no	no	no	HC
GUDCA+blood	FGF basic	GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.0766	0.65	no	no	dn	no	no	no	HC
GUDCA+blood	FGF basic	GUDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.0766	0.65	no	no	dn	no	no	no	HC
GUDCA+blood	FGF basic	GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.0766	0.65	no	no	dn	no	no	no	HC
GUDCA+blood	FGF basic	GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.0766	0.65	no	no	dn	no	no	no	HC
GUDCA+blood	FGF basic	GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.0766	0.65	no	no	dn	no	no	no	HC
GUDCA+blood	FGF basic	GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.0766	0.65	no	no	dn	no	no	no	HC
Acetic acid+stool	FGF basic	Acetic acid+stool-L-Homocystine+blood+FGF basic	Indirect	stool_scfa	serum_cytokines	0.0656	0.65	dn	no	no	no	no	no	HC
Alistipes	FGF basic	Alistipes+SFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes+20:3/16:0-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes+16:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Homovanillic acid+urine-L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-GDCA+stool-TXB2+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-MAPK signaling pathway-Cell adhesion molecules-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Lipid and atherosclerosis+AA+blood-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Progesterone-mediated oocyte maturation-Allograft rejection-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-MAPK signaling pathway-Allograft rejection-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Peroxisome-Cardiac muscle contraction+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Peroxisome-Alzheimer disease+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Progesterone-mediated oocyte maturation-Autoimmune thyroid disease-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-MAPK signaling pathway-Autoimmune thyroid disease-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Peroxisome-Prion disease+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Peroxisome-Huntington disease+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Progesterone-mediated oocyte maturation-Viral myocarditis-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Autophagy - animal-Viral myocarditis-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-MAPK signaling pathway-Viral myocarditis-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Cholinergic synapse-Viral myocarditis-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Peroxisome+P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Peroxisome-Non-alcoholic fatty liver disease+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Peroxisome-Thermogenesis+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-NOD-like receptor signaling pathway-Thermogenesis+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Autophagy - animal+AGE-RAGE signaling pathway in diabetic complications-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-GABAergic synapse+AGE-RAGE signaling pathway in diabetic complications-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-FoxO signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Peroxisome+AGE-RAGE signaling pathway in diabetic complications-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Autophagy - animal+L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-GABAergic synapse-Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-FoxO signaling pathway-Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Peroxisome-Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-NOD-like receptor signaling pathway-Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Olfactory transduction-Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Primary immunodeficiency-Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Peroxisome-Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Primary immunodeficiency-20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-16:0/18:2-PI+blood-20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes+Phenylacetic acid+stool+20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Central carbon metabolism in cancer-20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Peroxisome-20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Olfactory transduction-20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Progesterone-mediated oocyte maturation-Type I diabetes mellitus-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-MAPK signaling pathway-Type I diabetes mellitus-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-GABAergic synapse-Amyotrophic lateral sclerosis+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Peroxisome-Amyotrophic lateral sclerosis+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-NOD-like receptor signaling pathway-Amyotrophic lateral sclerosis+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Progesterone-mediated oocyte maturation-Graft-versus-host disease-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-MAPK signaling pathway-Graft-versus-host disease-FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-GABAergic synapse-Parkinson disease+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-Peroxisome-Parkinson disease+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Alistipes	FGF basic	Alistipes-NOD-like receptor signaling pathway-Parkinson disease+FGF basic	Indirect	Genus	serum_cytokines	0.0114	0.65	no	up	no	no	no	no	HC
Butyricimonas	FGF basic	Butyricimonas+Prion disease+FGF basic	Indirect	Genus	serum_cytokines	0.17	0.65	no	no	no	no	no	no	HC
Butyricimonas	FGF basic	Butyricimonas+Non-alcoholic fatty liver disease+FGF basic	Indirect	Genus	serum_cytokines	0.17	0.65	no	no	no	no	no	no	HC
Butyricimonas	FGF basic	Butyricimonas+Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.17	0.65	no	no	no	no	no	no	HC
Collinsella	FGF basic	Collinsella-L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.128	0.65	no	no	no	no	no	no	HC
iso-DCA+stool	FGF basic	iso-DCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.155	0.65	no	no	no	no	no	no	HC
LCA+stool	FGF basic	"LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+FGF basic"	Indirect	stool_bileacids	serum_cytokines	0.314	0.65	no	no	no	no	no	no	HC
LCA+stool	FGF basic	LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.314	0.65	no	no	no	no	no	no	HC
LCA+stool	FGF basic	LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.314	0.65	no	no	no	no	no	no	HC
LCA+stool	FGF basic	LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.314	0.65	no	no	no	no	no	no	HC
LCA+stool	FGF basic	LCA+stool-TCA+stool-20:0+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.314	0.65	no	no	no	no	no	no	HC
LCA+stool	FGF basic	LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.314	0.65	no	no	no	no	no	no	HC
LCA+stool	FGF basic	LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.314	0.65	no	no	no	no	no	no	HC
LCA+stool	FGF basic	LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.314	0.65	no	no	no	no	no	no	HC
LCA+stool	FGF basic	LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.314	0.65	no	no	no	no	no	no	HC
LCA+stool	FGF basic	LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.314	0.65	no	no	no	no	no	no	HC
LCA+stool	FGF basic	LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.314	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia+Systemic lupus erythematosus+Graft-versus-host disease-FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Ribosome-Phagosome-FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Ribosome+Cardiac muscle contraction+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Wnt signaling pathway+Retrograde endocannabinoid signaling+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Wnt signaling pathway+Prion disease+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Ribosome+Prion disease+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Ribosome-Endocytosis-FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Wnt signaling pathway+Thermogenesis+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Ribosome+Thermogenesis+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Wnt signaling pathway+Alzheimer disease+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Ribosome+Alzheimer disease+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Ribosome+mRNA surveillance pathway+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Wnt signaling pathway+Amyotrophic lateral sclerosis+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Ribosome+Amyotrophic lateral sclerosis+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia+Pertussis+16:0/22:6-PC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia+Systemic lupus erythematosus+Allograft rejection-FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Ribosome+RNA degradation+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Acetic acid+stool-L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Wnt signaling pathway-Cell adhesion molecules-FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Ribosome-Cell adhesion molecules-FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Wnt signaling pathway-Human papillomavirus infection-FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia+Pertussis+Human papillomavirus infection-FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Ribosome-Human papillomavirus infection-FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Wnt signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Ribosome+Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Wnt signaling pathway-Natural killer cell mediated cytotoxicity-FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Ribosome-Natural killer cell mediated cytotoxicity-FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Wnt signaling pathway+Non-alcoholic fatty liver disease+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Ribosome+Non-alcoholic fatty liver disease+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Wnt signaling pathway+Huntington disease+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Ribosome+Huntington disease+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Wnt signaling pathway+Parkinson disease+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Ribosome+Parkinson disease+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Wnt signaling pathway+Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Coronavirus disease - COVID-19+Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia-Ribosome+Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Akkermansia	FGF basic	Akkermansia+Systemic lupus erythematosus-Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.23	0.65	no	no	no	no	no	no	HC
Bifidobacterium	FGF basic	Bifidobacterium+TXB2+blood-FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	HC
Bifidobacterium	FGF basic	Bifidobacterium+AA+blood-FGF basic	Indirect	Genus	serum_cytokines	0.105	0.65	no	dn	no	no	no	no	HC
Ruminococcus	FGF basic	Ruminococcus+Thermogenesis+FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	HC
Ruminococcus	FGF basic	Ruminococcus-Endocytosis-FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	HC
Ruminococcus	FGF basic	Ruminococcus-P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	HC
Ruminococcus	FGF basic	Ruminococcus-Biosynthesis of amino acids-FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	HC
Ruminococcus	FGF basic	Ruminococcus+Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.335	0.65	no	no	no	no	no	no	HC
GCDCA+blood	FGF basic	GCDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.31	0.65	no	no	no	no	no	no	HC
GCDCA+blood	FGF basic	GCDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.31	0.65	no	no	no	no	no	no	HC
GCDCA+blood	FGF basic	GCDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.31	0.65	no	no	no	no	no	no	HC
GCDCA+blood	FGF basic	GCDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.31	0.65	no	no	no	no	no	no	HC
GCDCA+blood	FGF basic	GCDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.31	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]-18:0/22:6-PC+blood-20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]-Glutamatergic synapse-d18:1-22:0-SM+blood+FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]+24:0+blood+AA+blood-FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]-Aldosterone synthesis and secretion+Alzheimer disease+FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]-18:0/22:6-PC+blood+TXB2+blood-FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis+FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]-GnRH signaling pathway+Amyotrophic lateral sclerosis+FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]-Aldosterone synthesis and secretion+Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]-Morphine addiction+Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	"[Prevotella]-Growth hormone synthesis, secretion and action+L-Homocystine+blood+FGF basic"	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]-Aldosterone synthesis and secretion+L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]+24:0+blood-L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]-Aldosterone synthesis and secretion+Huntington disease+FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]-Aldosterone synthesis and secretion+Parkinson disease+FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]-GnRH signaling pathway+Parkinson disease+FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease+FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]-GnRH signaling pathway+Non-alcoholic fatty liver disease+FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]-Aldosterone synthesis and secretion+Prion disease+FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
[Prevotella]	FGF basic	[Prevotella]+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.367	0.65	no	no	no	no	no	no	HC
ACA+blood	FGF basic	ACA+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.338	0.65	no	no	no	no	no	no	HC
DCA+stool	FGF basic	DCA+stool-8-HETE+blood+TXB2+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.195	0.65	no	no	no	no	no	no	HC
DCA+stool	FGF basic	DCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.195	0.65	no	no	no	no	no	no	HC
DCA+stool	FGF basic	DCA+stool-20:1-LPA+blood-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.195	0.65	no	no	no	no	no	no	HC
DCA+stool	FGF basic	DCA+stool-8-HETE+blood-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.195	0.65	no	no	no	no	no	no	HC
DCA+stool	FGF basic	DCA+stool-8-HETE+blood+AA+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.195	0.65	no	no	no	no	no	no	HC
DCA+stool	FGF basic	DCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.195	0.65	no	no	no	no	no	no	HC
DCA+stool	FGF basic	DCA+stool-DL-methionine sulfoxide+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.195	0.65	no	no	no	no	no	no	HC
2-hydroxyhippuric acid+urine	FGF basic	2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic	Indirect	urine_cometabolism	serum_cytokines	0.215	0.65	no	no	no	no	no	no	HC
Butyric acid+stool	FGF basic	Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic	Indirect	stool_scfa	serum_cytokines	0.102	0.65	dn	no	no	no	no	no	HC
4-hydroxybenzoic acid+stool	FGF basic	4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.65	no	dn	no	no	no	no	HC
GCA+blood	FGF basic	GCA+blood+TCA+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.16	0.65	no	no	no	no	no	no	HC
GCA+blood	FGF basic	GCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.16	0.65	no	no	no	no	no	no	HC
GCA+blood	FGF basic	GCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.16	0.65	no	no	no	no	no	no	HC
GCA+blood	FGF basic	GCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.16	0.65	no	no	no	no	no	no	HC
ACA+stool	FGF basic	ACA+stool+UFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.417	0.65	no	no	no	no	no	no	HC
ACA+stool	FGF basic	ACA+stool-Acetic acid+stool-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.417	0.65	no	no	no	no	no	no	HC
CDCA+blood	FGF basic	CDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.506	0.65	no	no	no	no	no	no	HC
capric acid C6+blood	FGF basic	capric acid C6+blood-Cystine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_scfa	serum_cytokines	0.433	0.65	no	no	no	no	no	no	HC
capric acid C6+blood	FGF basic	capric acid C6+blood-Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_scfa	serum_cytokines	0.433	0.65	no	no	no	no	no	no	HC
capric acid C6+blood	FGF basic	capric acid C6+blood-Cystine+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic	Indirect	serum_scfa	serum_cytokines	0.433	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-Lysosome+Phagosome-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-UFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-18:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-16:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-16:0/20:3-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-18:1/18:1-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-SFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-16:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-18:1/20:4-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella+18:0/18:1-PE+blood-L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-iso-DCA+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-PUFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-24:1+blood-d18:1-22:0-SM+blood+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella+12-ketoDCA+blood-AA+blood-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-16:1/16:0-PC+blood+AA+blood-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-16:1/16:1-PC+blood+AA+blood-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Human papillomavirus infection-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Viral carcinogenesis-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella+Estrogen signaling pathway-Viral carcinogenesis-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-Lysosome+Viral carcinogenesis-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella+18:1-LPE+blood+L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-18:1/18:1-PC+blood+20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella+18:1-LPE+blood-TXB2+blood-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella+Estrogen signaling pathway-Autoimmune thyroid disease-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella+Estrogen signaling pathway-Allograft rejection-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella+Estrogen signaling pathway-Graft-versus-host disease-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella+Estrogen signaling pathway-Type I diabetes mellitus-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella+Estrogen signaling pathway-Viral myocarditis-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-16:0/16:0-PC+blood+16:0/22:6-PC+blood-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-Lysosome+Endocytosis-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
Prevotella	FGF basic	Prevotella-Lysosome+Natural killer cell mediated cytotoxicity-FGF basic	Indirect	Genus	serum_cytokines	0.287	0.65	no	no	no	no	no	no	HC
TCA+blood	FGF basic	TCA+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.339	0.65	no	no	no	no	no	no	HC
iso-DCA+blood	FGF basic	iso-DCA+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.38	0.65	no	no	no	no	no	no	HC
HCA+stool	FGF basic	HCA+stool-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.155	0.65	no	no	no	no	no	no	HC
Roseburia	FGF basic	Roseburia-L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.495	0.65	no	no	no	no	no	no	HC
Roseburia	FGF basic	Roseburia+TXB2+blood-FGF basic	Indirect	Genus	serum_cytokines	0.495	0.65	no	no	no	no	no	no	HC
12-ketoDCA+stool	FGF basic	12-ketoDCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.505	0.65	no	no	no	no	no	no	HC
12-ketoDCA+stool	FGF basic	12-ketoDCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.505	0.65	no	no	no	no	no	no	HC
GLCA+blood	FGF basic	GLCA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.319	0.65	no	no	no	no	no	no	HC
L-Tryptophan+stool	FGF basic	L-Tryptophan+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.557	0.65	no	no	no	no	no	no	HC
L-Tryptophan+stool	FGF basic	L-Tryptophan+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.557	0.65	no	no	no	no	no	no	HC
L-Tryptophan+stool	FGF basic	L-Tryptophan+stool+Phenylacetic acid+stool+20:0+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.557	0.65	no	no	no	no	no	no	HC
L-Tryptophan+stool	FGF basic	L-Tryptophan+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.557	0.65	no	no	no	no	no	no	HC
L-Tryptophan+stool	FGF basic	L-Tryptophan+stool-12-ketoDCA+blood-AA+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.557	0.65	no	no	no	no	no	no	HC
CA+blood	FGF basic	CA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.606	0.65	no	no	no	no	no	no	HC
GUDCA+stool	FGF basic	GUDCA+stool+Phenylacetic acid+stool+20:0+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0085	0.65	no	dn	no	no	no	no	HC
GUDCA+stool	FGF basic	GUDCA+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0085	0.65	no	dn	no	no	no	no	HC
L-Phenylalanine+stool	FGF basic	L-Phenylalanine+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.398	0.65	no	no	no	no	no	no	HC
L-Phenylalanine+stool	FGF basic	L-Phenylalanine+stool-12-ketoDCA+blood-AA+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.398	0.65	no	no	no	no	no	no	HC
L-Phenylalanine+stool	FGF basic	L-Phenylalanine+stool+Phenylacetic acid+stool+20:0+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.398	0.65	no	no	no	no	no	no	HC
L-Phenylalanine+stool	FGF basic	L-Phenylalanine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.398	0.65	no	no	no	no	no	no	HC
L-Phenylalanine+stool	FGF basic	L-Phenylalanine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.398	0.65	no	no	no	no	no	no	HC
butyric acid C4+blood	FGF basic	butyric acid C4+blood+Cystine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_scfa	serum_cytokines	0.407	0.65	no	no	no	no	no	no	HC
butyric acid C4+blood	FGF basic	butyric acid C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_scfa	serum_cytokines	0.407	0.65	no	no	no	no	no	no	HC
butyric acid C4+blood	FGF basic	butyric acid C4+blood+Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_scfa	serum_cytokines	0.407	0.65	no	no	no	no	no	no	HC
butyric acid C4+blood	FGF basic	butyric acid C4+blood+Cystine+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic	Indirect	serum_scfa	serum_cytokines	0.407	0.65	no	no	no	no	no	no	HC
GCA+stool	FGF basic	GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0809	0.65	no	no	no	no	no	no	HC
GCA+stool	FGF basic	GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0809	0.65	no	no	no	no	no	no	HC
GCA+stool	FGF basic	GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0809	0.65	no	no	no	no	no	no	HC
GCA+stool	FGF basic	GCA+stool+18:0/22:6-PE+blood-20:0+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0809	0.65	no	no	no	no	no	no	HC
GCA+stool	FGF basic	GCA+stool+GDCA+stool-TXB2+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0809	0.65	no	no	no	no	no	no	HC
GCA+stool	FGF basic	GCA+stool-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0809	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus-18:1/18:2-PG+blood+AA+blood-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus-Lysosome+Viral carcinogenesis-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Ribosome biogenesis in eukaryotes-Viral carcinogenesis-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus-Influenza A+Viral carcinogenesis-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+TCA+stool-20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Primary immunodeficiency-20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Central carbon metabolism in cancer-20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Lachnospira-20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus-18:1-LPC+blood+20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus-Phenylacetic acid+stool+20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus-18:2-LPC+blood+20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Primary immunodeficiency-Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Lachnospira-L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus-18:1-LPC+blood+L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus-Lysosome+Endocytosis-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Ribosome biogenesis in eukaryotes-Endocytosis-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus-Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Ribosome biogenesis in eukaryotes-Allograft rejection-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus-Influenza A+Allograft rejection-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Ribosome biogenesis in eukaryotes-Cell adhesion molecules-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Ribosome biogenesis in eukaryotes-Autoimmune thyroid disease-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus-Influenza A+Autoimmune thyroid disease-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Ribosome biogenesis in eukaryotes-Cellular senescence-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus-Lysosome+Natural killer cell mediated cytotoxicity-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Ribosome biogenesis in eukaryotes-Natural killer cell mediated cytotoxicity-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Ribosome biogenesis in eukaryotes-Graft-versus-host disease-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus-Influenza A+Graft-versus-host disease-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Ribosome biogenesis in eukaryotes-Human papillomavirus infection-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus-Influenza A+Human papillomavirus infection-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Ribosome biogenesis in eukaryotes+mRNA surveillance pathway+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus-Lysosome+Phagosome-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Ribosome biogenesis in eukaryotes-Phagosome-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Ribosome biogenesis in eukaryotes+RNA degradation+FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Ribosome biogenesis in eukaryotes-Type I diabetes mellitus-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus+Ribosome biogenesis in eukaryotes-Viral myocarditis-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Coprococcus	FGF basic	Coprococcus-Influenza A+Viral myocarditis-FGF basic	Indirect	Genus	serum_cytokines	0.612	0.65	no	no	no	no	no	no	HC
Oscillospira	FGF basic	Oscillospira-P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	HC
Oscillospira	FGF basic	Oscillospira+L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.62	0.65	no	no	no	no	no	no	HC
HCA+blood	FGF basic	HCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.544	0.65	no	no	no	no	no	no	HC
iso-LCA+stool	FGF basic	iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.72	0.65	no	no	no	no	no	no	HC
iso-LCA+stool	FGF basic	iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.72	0.65	no	no	no	no	no	no	HC
iso-LCA+stool	FGF basic	iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.72	0.65	no	no	no	no	no	no	HC
iso-LCA+stool	FGF basic	iso-LCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.72	0.65	no	no	no	no	no	no	HC
iso-LCA+stool	FGF basic	iso-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.72	0.65	no	no	no	no	no	no	HC
iso-LCA+stool	FGF basic	iso-LCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.72	0.65	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	FGF basic	2-methyl-butyric acid m-C4+blood+20:1+blood-22:6n3+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_scfa	serum_cytokines	0.262	0.65	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	FGF basic	2-methyl-butyric acid m-C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_scfa	serum_cytokines	0.262	0.65	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	FGF basic	2-methyl-butyric acid m-C4+blood+decanoic acid C10+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_scfa	serum_cytokines	0.262	0.65	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	FGF basic	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+UFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_scfa	serum_cytokines	0.262	0.65	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	FGF basic	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_scfa	serum_cytokines	0.262	0.65	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	FGF basic	2-methyl-butyric acid m-C4+blood-22:2-LPA+blood-d18:0-24:1-SM+blood+d18:1-22:0-SM+blood+FGF basic	Indirect	serum_scfa	serum_cytokines	0.262	0.65	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	FGF basic	2-methyl-butyric acid m-C4+blood+20:1+blood+20:1-LPC+blood-TXB2+blood-FGF basic	Indirect	serum_scfa	serum_cytokines	0.262	0.65	no	no	no	no	no	no	HC
DCA+blood	FGF basic	DCA+blood+GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.122	0.65	no	no	no	no	no	no	HC
DCA+blood	FGF basic	DCA+blood+GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.122	0.65	no	no	no	no	no	no	HC
DCA+blood	FGF basic	DCA+blood+GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.122	0.65	no	no	no	no	no	no	HC
DCA+blood	FGF basic	DCA+blood+GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.122	0.65	no	no	no	no	no	no	HC
DCA+blood	FGF basic	DCA+blood+GUDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.122	0.65	no	no	no	no	no	no	HC
DCA+blood	FGF basic	DCA+blood+GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.122	0.65	no	no	no	no	no	no	HC
DCA+blood	FGF basic	"DCA+blood-n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic"	Indirect	serum_bileacids	serum_cytokines	0.122	0.65	no	no	no	no	no	no	HC
DCA+blood	FGF basic	DCA+blood+GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.122	0.65	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	FGF basic	3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.33	0.65	no	no	no	no	no	no	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	FGF basic	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.65	up	up	no	no	no	no	HC
GLCA+stool	FGF basic	GLCA+stool-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.617	0.65	no	no	no	no	no	no	HC
GLCA+stool	FGF basic	GLCA+stool-iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.617	0.65	no	no	no	no	no	no	HC
GLCA+stool	FGF basic	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.617	0.65	no	no	no	no	no	no	HC
GLCA+stool	FGF basic	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.617	0.65	no	no	no	no	no	no	HC
GLCA+stool	FGF basic	GLCA+stool-iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.617	0.65	no	no	no	no	no	no	HC
GLCA+stool	FGF basic	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.617	0.65	no	no	no	no	no	no	HC
GLCA+stool	FGF basic	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.617	0.65	no	no	no	no	no	no	HC
GLCA+stool	FGF basic	GLCA+stool-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.617	0.65	no	no	no	no	no	no	HC
GLCA+stool	FGF basic	GLCA+stool-iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.617	0.65	no	no	no	no	no	no	HC
GLCA+stool	FGF basic	"GLCA+stool-LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+FGF basic"	Indirect	stool_bileacids	serum_cytokines	0.617	0.65	no	no	no	no	no	no	HC
GLCA+stool	FGF basic	GLCA+stool-iso-LCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.617	0.65	no	no	no	no	no	no	HC
GLCA+stool	FGF basic	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.617	0.65	no	no	no	no	no	no	HC
GLCA+stool	FGF basic	GLCA+stool-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.617	0.65	no	no	no	no	no	no	HC
GLCA+stool	FGF basic	GLCA+stool-iso-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.617	0.65	no	no	no	no	no	no	HC
GLCA+stool	FGF basic	GLCA+stool-LCA+stool-TCA+stool-20:0+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.617	0.65	no	no	no	no	no	no	HC
GLCA+stool	FGF basic	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.617	0.65	no	no	no	no	no	no	HC
GLCA+stool	FGF basic	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.617	0.65	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	FGF basic	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.304	0.65	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	FGF basic	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.304	0.65	no	no	no	no	no	no	HC
TCA+stool	FGF basic	TCA+stool-20:0+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.458	0.65	no	no	no	no	no	no	HC
HDCA+stool	FGF basic	HDCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	HC
HDCA+stool	FGF basic	HDCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	HC
HDCA+stool	FGF basic	HDCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	HC
HDCA+stool	FGF basic	HDCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	HC
HDCA+stool	FGF basic	HDCA+stool+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	HC
HDCA+stool	FGF basic	HDCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	HC
HDCA+stool	FGF basic	HDCA+stool+16:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	HC
HDCA+stool	FGF basic	HDCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	HC
HDCA+stool	FGF basic	HDCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	HC
HDCA+stool	FGF basic	HDCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	HC
HDCA+stool	FGF basic	HDCA+stool+20:3/16:0-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.176	0.65	no	no	no	no	no	no	HC
Lachnospira	FGF basic	Lachnospira-L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	HC
Lachnospira	FGF basic	Lachnospira-20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.279	0.65	no	no	no	no	no	no	HC
isobutyric acid C4+blood	FGF basic	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_scfa	serum_cytokines	0.0151	0.65	up	up	no	no	no	no	HC
isobutyric acid C4+blood	FGF basic	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_scfa	serum_cytokines	0.0151	0.65	up	up	no	no	no	no	HC
isobutyric acid C4+blood	FGF basic	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_scfa	serum_cytokines	0.0151	0.65	up	up	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool-9-HODE+blood-L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood+TXB2+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood-TXB2+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood-20:0+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool-Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool-9-HODE+blood+GPC+blood-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood+L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool+18:0/20:5-PC+blood-20:0-LPE+blood+d18:1-22:0-SM+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool+18:0/20:5-PC+blood+18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool+18:0/20:5-PC+blood+UFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool+18:0/20:5-PC+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool+18:0/20:5-PC+blood+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool+18:0/20:5-PC+blood+18:1/18:0-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
GCDCA+stool	FGF basic	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine-L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.0471	0.65	no	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool+GCA+stool-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool+GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool+GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool+GCA+stool+GDCA+stool-TXB2+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	FGF basic	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-20:0+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.65	dn	dn	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Endocrine resistance+Huntington disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Long-term depression+Huntington disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Pancreatic secretion+Huntington disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Aldosterone synthesis and secretion+Huntington disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Cushing syndrome+Huntington disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Endocrine resistance+L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Long-term depression+L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Pancreatic secretion+L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Aldosterone synthesis and secretion+L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter+Arginine and proline metabolism+Biosynthesis of amino acids-FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Endocrine resistance+mRNA surveillance pathway+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Long-term depression-P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Pancreatic secretion-P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Long-term depression+Prion disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Pancreatic secretion+Prion disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Aldosterone synthesis and secretion+Prion disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Endocrine resistance+Non-alcoholic fatty liver disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Long-term depression+Non-alcoholic fatty liver disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Endocrine resistance+Parkinson disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Long-term depression+Parkinson disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter+Arginine and proline metabolism-Parkinson disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Pancreatic secretion+Parkinson disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Aldosterone synthesis and secretion+Parkinson disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Cushing syndrome+Parkinson disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Endocrine resistance+Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Long-term depression+Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter+Arginine and proline metabolism-Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Pancreatic secretion+Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Cushing syndrome+Pathways of neurodegeneration - multiple diseases+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Endocrine resistance+RNA degradation+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter+Arginine and proline metabolism-RNA degradation+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Endocrine resistance+Alzheimer disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Long-term depression+Alzheimer disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Pancreatic secretion+Alzheimer disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Aldosterone synthesis and secretion+Alzheimer disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Cushing syndrome+Alzheimer disease+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Phospholipase D signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Endocrine resistance+Thermogenesis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter+Arginine and proline metabolism-Thermogenesis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Endocrine resistance+Amyotrophic lateral sclerosis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Long-term depression+Amyotrophic lateral sclerosis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter+Arginine and proline metabolism-Amyotrophic lateral sclerosis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Pancreatic secretion+Amyotrophic lateral sclerosis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Cushing syndrome+Amyotrophic lateral sclerosis+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Pancreatic secretion+20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Morphine addiction+Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Long-term depression+Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Pancreatic secretion+Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Aldosterone synthesis and secretion+Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Odoribacter	FGF basic	Odoribacter-Cushing syndrome+Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.798	0.65	no	no	no	no	no	no	HC
Isobutyric acid+stool	FGF basic	Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic	Indirect	stool_scfa	serum_cytokines	0.408	0.65	no	no	no	no	no	no	HC
Isobutyric acid+stool	FGF basic	Isobutyric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_scfa	serum_cytokines	0.408	0.65	no	no	no	no	no	no	HC
Kynurenic acid+stool	FGF basic	Kynurenic acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.037	0.65	dn	dn	no	no	no	no	HC
L-Tryptophan+urine	FGF basic	L-Tryptophan+urine+FGF basic	Direct	urine_cometabolism	serum_cytokines	0.226	0.65	no	no	no	no	no	no	HC
Eggerthella	FGF basic	Eggerthella+Bacteroides-FGF basic	Indirect	Genus	serum_cytokines	0.912	0.65	no	no	no	no	no	no	HC
Anaerotruncus	FGF basic	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic	Indirect	Genus	serum_cytokines	0.904	0.65	no	no	no	no	no	no	HC
Anaerotruncus	FGF basic	Anaerotruncus-Gemmiger-Tuberculosis+Graft-versus-host disease-FGF basic	Indirect	Genus	serum_cytokines	0.904	0.65	no	no	no	no	no	no	HC
Anaerotruncus	FGF basic	Anaerotruncus-Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.904	0.65	no	no	no	no	no	no	HC
Anaerotruncus	FGF basic	Anaerotruncus-Gemmiger-Tuberculosis-Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.904	0.65	no	no	no	no	no	no	HC
Anaerotruncus	FGF basic	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Viral myocarditis-FGF basic	Indirect	Genus	serum_cytokines	0.904	0.65	no	no	no	no	no	no	HC
Anaerotruncus	FGF basic	Anaerotruncus-Gemmiger-Tuberculosis+Viral myocarditis-FGF basic	Indirect	Genus	serum_cytokines	0.904	0.65	no	no	no	no	no	no	HC
Anaerotruncus	FGF basic	Anaerotruncus-Gemmiger-GPC+blood-L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.904	0.65	no	no	no	no	no	no	HC
Anaerotruncus	FGF basic	Anaerotruncus-Gemmiger-20:1-LPA+blood-L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.904	0.65	no	no	no	no	no	no	HC
Anaerotruncus	FGF basic	Anaerotruncus-Gemmiger-TUDCA+blood-L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.904	0.65	no	no	no	no	no	no	HC
Anaerotruncus	FGF basic	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Allograft rejection-FGF basic	Indirect	Genus	serum_cytokines	0.904	0.65	no	no	no	no	no	no	HC
Anaerotruncus	FGF basic	Anaerotruncus-Gemmiger-Tuberculosis+Allograft rejection-FGF basic	Indirect	Genus	serum_cytokines	0.904	0.65	no	no	no	no	no	no	HC
Anaerotruncus	FGF basic	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic	Indirect	Genus	serum_cytokines	0.904	0.65	no	no	no	no	no	no	HC
Anaerotruncus	FGF basic	Anaerotruncus-Gemmiger-Tuberculosis+Autoimmune thyroid disease-FGF basic	Indirect	Genus	serum_cytokines	0.904	0.65	no	no	no	no	no	no	HC
Anaerotruncus	FGF basic	Anaerotruncus-Gemmiger+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.904	0.65	no	no	no	no	no	no	HC
Anaerotruncus	FGF basic	Anaerotruncus-Gemmiger-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.904	0.65	no	no	no	no	no	no	HC
Anaerostipes	FGF basic	Anaerostipes-20:0+blood+FGF basic	Indirect	Genus	serum_cytokines	0.568	0.65	no	no	no	no	no	no	HC
Isovaleric acid+stool	FGF basic	Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic	Indirect	stool_scfa	serum_cytokines	0.343	0.65	no	no	no	no	no	no	HC
Isovaleric acid+stool	FGF basic	Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic	Indirect	stool_scfa	serum_cytokines	0.343	0.65	no	no	no	no	no	no	HC
Isovaleric acid+stool	FGF basic	Isovaleric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_scfa	serum_cytokines	0.343	0.65	no	no	no	no	no	no	HC
Paraprevotella	FGF basic	Paraprevotella-L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.118	0.65	no	no	no	no	no	no	HC
Paraprevotella	FGF basic	Paraprevotella+AA+blood-FGF basic	Indirect	Genus	serum_cytokines	0.118	0.65	no	no	no	no	no	no	HC
Homovanillic acid+urine	FGF basic	Homovanillic acid+urine-L-Tryptophan+urine+FGF basic	Indirect	urine_cometabolism	serum_cytokines	0.45	0.65	no	no	no	no	no	no	HC
Homovanillic acid+urine	FGF basic	Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic	Indirect	urine_cometabolism	serum_cytokines	0.45	0.65	no	no	no	no	no	no	HC
TDCA+blood	FGF basic	TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.155	0.65	no	up	no	no	no	no	HC
iso-LCA+blood	FGF basic	iso-LCA+blood-TUDCA+blood-L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.507	0.65	no	no	no	no	no	no	HC
iso-LCA+blood	FGF basic	iso-LCA+blood-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.507	0.65	no	no	no	no	no	no	HC
iso-LCA+blood	FGF basic	iso-LCA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.507	0.65	no	no	no	no	no	no	HC
¦Ø-MCA+stool	FGF basic	¦Ø-MCA+stool-Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.919	0.65	no	no	no	no	no	no	HC
¦Ø-MCA+stool	FGF basic	¦Ø-MCA+stool-Acetic acid+stool-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.919	0.65	no	no	no	no	no	no	HC
Phenylacetic acid+stool	FGF basic	Phenylacetic acid+stool+20:0+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.785	0.65	no	no	no	no	no	no	HC
Phenylacetic acid+stool	FGF basic	Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.785	0.65	no	no	no	no	no	no	HC
Gemmiger	FGF basic	Gemmiger-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	HC
Gemmiger	FGF basic	Gemmiger-Tuberculosis+Graft-versus-host disease-FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	HC
Gemmiger	FGF basic	Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	HC
Gemmiger	FGF basic	Gemmiger-Tuberculosis-Diabetic cardiomyopathy+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	HC
Gemmiger	FGF basic	Gemmiger-Staphylococcus aureus infection+Viral myocarditis-FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	HC
Gemmiger	FGF basic	Gemmiger-Tuberculosis+Viral myocarditis-FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	HC
Gemmiger	FGF basic	Gemmiger-GPC+blood-L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	HC
Gemmiger	FGF basic	Gemmiger-20:1-LPA+blood-L-Homocystine+blood+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	HC
Gemmiger	FGF basic	Gemmiger-TUDCA+blood-L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	HC
Gemmiger	FGF basic	Gemmiger-Staphylococcus aureus infection+Allograft rejection-FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	HC
Gemmiger	FGF basic	Gemmiger-Tuberculosis+Allograft rejection-FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	HC
Gemmiger	FGF basic	Gemmiger-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	HC
Gemmiger	FGF basic	Gemmiger-Tuberculosis+Autoimmune thyroid disease-FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	HC
Gemmiger	FGF basic	Gemmiger+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	HC
Gemmiger	FGF basic	Gemmiger-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.595	0.65	no	no	no	no	no	no	HC
GDCA+stool	FGF basic	GDCA+stool-TXB2+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.656	0.65	no	no	no	no	no	no	HC
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	HC
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	HC
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool+PUFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	HC
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool+20:1-LPA+blood-L-Homocystine+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	HC
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool+8-HETE+blood-L-Homocystine+blood+FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	HC
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool-12-ketoDCA+blood-AA+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	HC
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool+8-HETE+blood+AA+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	HC
L-Tyrosine+stool	FGF basic	L-Tyrosine+stool+8-HETE+blood+TXB2+blood-FGF basic	Indirect	stool_cometabolism	serum_cytokines	0.44	0.65	no	no	no	no	no	no	HC
CDCA+stool	FGF basic	CDCA+stool+18:3n3+blood+AA+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.663	0.65	no	no	no	no	no	no	HC
CDCA+stool	FGF basic	CDCA+stool+TUDCA+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.663	0.65	no	no	no	no	no	no	HC
CDCA+stool	FGF basic	CDCA+stool+nutriCA+stool-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.663	0.65	no	no	no	no	no	no	HC
CDCA+stool	FGF basic	CDCA+stool+HCA+stool-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.663	0.65	no	no	no	no	no	no	HC
CDCA+stool	FGF basic	CDCA+stool+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.663	0.65	no	no	no	no	no	no	HC
CDCA+stool	FGF basic	CDCA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.663	0.65	no	no	no	no	no	no	HC
CDCA+stool	FGF basic	CDCA+stool-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.663	0.65	no	no	no	no	no	no	HC
CA+stool	FGF basic	CA+stool+nutriCA+stool-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.827	0.65	no	no	no	no	no	no	HC
CA+stool	FGF basic	CA+stool+HCA+stool-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.827	0.65	no	no	no	no	no	no	HC
CA+stool	FGF basic	CA+stool-ACA+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.827	0.65	no	no	no	no	no	no	HC
CA+stool	FGF basic	CA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.827	0.65	no	no	no	no	no	no	HC
CA+stool	FGF basic	CA+stool+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.827	0.65	no	no	no	no	no	no	HC
CA+stool	FGF basic	CA+stool-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.827	0.65	no	no	no	no	no	no	HC
CA+stool	FGF basic	CA+stool+GDCA+stool-TXB2+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.827	0.65	no	no	no	no	no	no	HC
CA+stool	FGF basic	CA+stool+TUDCA+blood-L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.827	0.65	no	no	no	no	no	no	HC
CA+stool	FGF basic	CA+stool-18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.827	0.65	no	no	no	no	no	no	HC
HDCA+blood	FGF basic	HDCA+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.483	0.65	no	no	no	no	no	no	HC
HDCA+blood	FGF basic	HDCA+blood+UFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.483	0.65	no	no	no	no	no	no	HC
HDCA+blood	FGF basic	HDCA+blood+SFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.483	0.65	no	no	no	no	no	no	HC
HDCA+blood	FGF basic	HDCA+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.483	0.65	no	no	no	no	no	no	HC
UDCA+stool	FGF basic	UDCA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.266	0.65	no	no	no	no	no	no	HC
UDCA+stool	FGF basic	UDCA+stool+18:3n3+blood+AA+blood-FGF basic	Indirect	stool_bileacids	serum_cytokines	0.266	0.65	no	no	no	no	no	no	HC
LCA+blood	FGF basic	LCA+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.884	0.65	no	no	no	no	no	no	HC
nutriCA+stool	FGF basic	nutriCA+stool-L-Homocystine+blood+FGF basic	Indirect	stool_bileacids	serum_cytokines	0.481	0.65	no	no	no	no	no	no	HC
GDCA+blood	FGF basic	GDCA+blood+TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic	Indirect	serum_bileacids	serum_cytokines	0.632	0.65	no	no	no	no	no	no	HC
P-hydroxyhippuric acid+urine	FGF basic	P-hydroxyhippuric acid+urine-FGF basic	Direct	urine_cometabolism	serum_cytokines	0.436	0.65	no	no	no	no	no	no	HC
acetic acid C2+blood	FGF basic	acetic acid C2+blood-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic	Indirect	serum_scfa	serum_cytokines	0.000193	0.65	up	dn	no	no	no	no	HC
isovaleric acid iso-C5+blood	FGF basic	isovaleric acid iso-C5+blood+Sarcosine+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic	Indirect	serum_scfa	serum_cytokines	0.117	0.65	no	no	no	no	no	no	HC
L-Phenylalanine+urine	FGF basic	L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic	Indirect	urine_cometabolism	serum_cytokines	0.0908	0.65	no	up	no	no	no	no	HC
Clostridium	FGF basic	Clostridium+P-hydroxyhippuric acid+urine-FGF basic	Indirect	Genus	serum_cytokines	0.925	0.65	no	no	no	no	no	no	HC
Clostridium	FGF basic	Clostridium-L-Tryptophan+urine+FGF basic	Indirect	Genus	serum_cytokines	0.925	0.65	no	no	no	no	no	no	HC
12-ketoDCA+blood	FGF basic	12-ketoDCA+blood-AA+blood-FGF basic	Indirect	serum_bileacids	serum_cytokines	0.517	0.65	no	no	no	no	no	no	HC
Butyricicoccus	FGF basic	Butyricicoccus+d18:1-22:0-SM+blood+FGF basic	Indirect	Genus	serum_cytokines	0.852	0.65	no	no	no	no	no	no	HC
3-Hydroxy-L-kynurenine+urine	FGF basic	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine+FGF basic	Indirect	urine_cometabolism	serum_cytokines	0.401	0.65	no	no	no	no	no	no	HC
Wautersiella	FGF basic	Wautersiella+Butyricicoccus+d18:1-22:0-SM+blood+FGF basic	Indirect	Genus	serum_cytokines	0.289	0.65	no	no	no	no	no	no	HC
Blautia	IL-6	Blautia+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	1.36E-05	0.52	up	dn	dn	no	no	no	HC
Parabacteroides	IL-6	Parabacteroides+Biosynthesis of amino acids-FGF basic+IL-6	Indirect	Genus	serum_cytokines	4.19E-05	0.52	no	up	up	no	no	no	HC
Parabacteroides	IL-6	Parabacteroides-RNA degradation+FGF basic+IL-6	Indirect	Genus	serum_cytokines	4.19E-05	0.52	no	up	up	no	no	no	HC
Parabacteroides	IL-6	Parabacteroides-mRNA surveillance pathway+FGF basic+IL-6	Indirect	Genus	serum_cytokines	4.19E-05	0.52	no	up	up	no	no	no	HC
Dorea	IL-6	Dorea-VEGF signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Fc epsilon RI signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-18:2-LPC+blood+20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Endocrine resistance+Huntington disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Endocrine resistance+L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Chemical carcinogenesis - receptor activation+L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	"Dorea-Growth hormone synthesis, secretion and action+L-Homocystine+blood+FGF basic+IL-6"	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Endocrine resistance+mRNA surveillance pathway+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Endocrine resistance+Non-alcoholic fatty liver disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-GnRH signaling pathway+Non-alcoholic fatty liver disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Endocrine resistance+Parkinson disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-GnRH signaling pathway+Parkinson disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Endocrine resistance+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Endocrine resistance+RNA degradation+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Endocrine resistance+Thermogenesis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Thyroid hormone signaling pathway+Viral myocarditis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Chemical carcinogenesis - receptor activation-Viral myocarditis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-16:0-LPC+blood+AA+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Amphetamine addiction-Human papillomavirus infection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Amphetamine addiction-Autoimmune thyroid disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Chemical carcinogenesis - receptor activation-Autoimmune thyroid disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-16:0-LPC+blood+TXB2+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Amphetamine addiction-Allograft rejection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Chemical carcinogenesis - receptor activation-Allograft rejection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Amphetamine addiction-Graft-versus-host disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Chemical carcinogenesis - receptor activation-Graft-versus-host disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea+Legionellosis-Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Amphetamine addiction+Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Chemical carcinogenesis - receptor activation+Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Amphetamine addiction-Viral carcinogenesis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Endocrine resistance+Amyotrophic lateral sclerosis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-GnRH signaling pathway+Amyotrophic lateral sclerosis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Chemical carcinogenesis - receptor activation-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Dorea	IL-6	Dorea-Endocrine resistance+Alzheimer disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.00362	0.52	up	no	dn	no	no	no	HC
Faecalibacterium	IL-6	Faecalibacterium+Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0039	0.52	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-6	Faecalibacterium-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0039	0.52	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-6	Faecalibacterium-Staphylococcus aureus infection+Viral myocarditis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0039	0.52	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-6	Faecalibacterium-Staphylococcus aureus infection+Allograft rejection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0039	0.52	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-6	Faecalibacterium-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0039	0.52	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-6	Faecalibacterium+4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0039	0.52	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-6	Faecalibacterium-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0039	0.52	no	dn	dn	no	no	no	HC
TUDCA+blood	IL-6	TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.0282	0.52	no	no	dn	no	no	no	HC
TUDCA+blood	IL-6	TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.0282	0.52	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	IL-6	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.0458	0.52	no	no	dn	no	no	no	HC
Bacteroides	IL-6	Bacteroides-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.000267	0.52	dn	dn	up	no	no	no	HC
Propionic acid+stool	IL-6	Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_scfa	serum_cytokines	0.0436	0.52	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-6	Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_scfa	serum_cytokines	0.0436	0.52	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-6	Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_scfa	serum_cytokines	0.0436	0.52	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-6	Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_scfa	serum_cytokines	0.0436	0.52	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-6	Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic+IL-6	Indirect	stool_scfa	serum_cytokines	0.0436	0.52	dn	no	up	no	no	no	HC
[Ruminococcus]	IL-6	[Ruminococcus]+nutriCA+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0679	0.52	no	no	dn	no	no	no	HC
[Ruminococcus]	IL-6	[Ruminococcus]+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0679	0.52	no	no	dn	no	no	no	HC
[Ruminococcus]	IL-6	[Ruminococcus]-Hypotaurine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0679	0.52	no	no	dn	no	no	no	HC
GUDCA+blood	IL-6	GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.0766	0.52	no	no	dn	no	no	no	HC
GUDCA+blood	IL-6	GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.0766	0.52	no	no	dn	no	no	no	HC
GUDCA+blood	IL-6	GUDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.0766	0.52	no	no	dn	no	no	no	HC
GUDCA+blood	IL-6	GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.0766	0.52	no	no	dn	no	no	no	HC
GUDCA+blood	IL-6	GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.0766	0.52	no	no	dn	no	no	no	HC
GUDCA+blood	IL-6	GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.0766	0.52	no	no	dn	no	no	no	HC
GUDCA+blood	IL-6	GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.0766	0.52	no	no	dn	no	no	no	HC
Acetic acid+stool	IL-6	Acetic acid+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_scfa	serum_cytokines	0.0656	0.52	dn	no	no	no	no	no	HC
Alistipes	IL-6	Alistipes+SFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes+20:3/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes+16:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-GDCA+stool-TXB2+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-MAPK signaling pathway-Cell adhesion molecules-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Lipid and atherosclerosis+AA+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Progesterone-mediated oocyte maturation-Allograft rejection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-MAPK signaling pathway-Allograft rejection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Peroxisome-Cardiac muscle contraction+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Peroxisome-Alzheimer disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Progesterone-mediated oocyte maturation-Autoimmune thyroid disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-MAPK signaling pathway-Autoimmune thyroid disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Peroxisome-Prion disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Peroxisome-Huntington disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Progesterone-mediated oocyte maturation-Viral myocarditis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Autophagy - animal-Viral myocarditis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-MAPK signaling pathway-Viral myocarditis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Cholinergic synapse-Viral myocarditis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Peroxisome+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Peroxisome-Non-alcoholic fatty liver disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Peroxisome-Thermogenesis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-NOD-like receptor signaling pathway-Thermogenesis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Autophagy - animal+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-GABAergic synapse+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-FoxO signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Peroxisome+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Autophagy - animal+L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-GABAergic synapse-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-FoxO signaling pathway-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Peroxisome-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-NOD-like receptor signaling pathway-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Olfactory transduction-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Primary immunodeficiency-Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Peroxisome-Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Primary immunodeficiency-20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-16:0/18:2-PI+blood-20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Central carbon metabolism in cancer-20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Peroxisome-20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Olfactory transduction-20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Progesterone-mediated oocyte maturation-Type I diabetes mellitus-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-MAPK signaling pathway-Type I diabetes mellitus-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-GABAergic synapse-Amyotrophic lateral sclerosis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Peroxisome-Amyotrophic lateral sclerosis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-NOD-like receptor signaling pathway-Amyotrophic lateral sclerosis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Progesterone-mediated oocyte maturation-Graft-versus-host disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-MAPK signaling pathway-Graft-versus-host disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-GABAergic synapse-Parkinson disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-Peroxisome-Parkinson disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Alistipes	IL-6	Alistipes-NOD-like receptor signaling pathway-Parkinson disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.0114	0.52	no	up	no	no	no	no	HC
Butyricimonas	IL-6	Butyricimonas+Prion disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	HC
Butyricimonas	IL-6	Butyricimonas+Non-alcoholic fatty liver disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	HC
Butyricimonas	IL-6	Butyricimonas+Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.17	0.52	no	no	no	no	no	no	HC
Collinsella	IL-6	Collinsella-L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.128	0.52	no	no	no	no	no	no	HC
iso-DCA+stool	IL-6	iso-DCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.155	0.52	no	no	no	no	no	no	HC
LCA+stool	IL-6	"LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+FGF basic+IL-6"	Indirect	stool_bileacids	serum_cytokines	0.314	0.52	no	no	no	no	no	no	HC
LCA+stool	IL-6	LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.314	0.52	no	no	no	no	no	no	HC
LCA+stool	IL-6	LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.314	0.52	no	no	no	no	no	no	HC
LCA+stool	IL-6	LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.314	0.52	no	no	no	no	no	no	HC
LCA+stool	IL-6	LCA+stool-TCA+stool-20:0+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.314	0.52	no	no	no	no	no	no	HC
LCA+stool	IL-6	LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.314	0.52	no	no	no	no	no	no	HC
LCA+stool	IL-6	LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.314	0.52	no	no	no	no	no	no	HC
LCA+stool	IL-6	LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.314	0.52	no	no	no	no	no	no	HC
LCA+stool	IL-6	LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.314	0.52	no	no	no	no	no	no	HC
LCA+stool	IL-6	LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.314	0.52	no	no	no	no	no	no	HC
LCA+stool	IL-6	LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.314	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia+Systemic lupus erythematosus+Graft-versus-host disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Ribosome-Phagosome-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Ribosome+Cardiac muscle contraction+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Wnt signaling pathway+Retrograde endocannabinoid signaling+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Wnt signaling pathway+Prion disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Ribosome+Prion disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Ribosome-Endocytosis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Wnt signaling pathway+Thermogenesis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Ribosome+Thermogenesis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Wnt signaling pathway+Alzheimer disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Ribosome+Alzheimer disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Ribosome+mRNA surveillance pathway+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Wnt signaling pathway+Amyotrophic lateral sclerosis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Ribosome+Amyotrophic lateral sclerosis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia+Pertussis+16:0/22:6-PC+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia+Systemic lupus erythematosus+Allograft rejection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Ribosome+RNA degradation+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Acetic acid+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Wnt signaling pathway-Cell adhesion molecules-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Ribosome-Cell adhesion molecules-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Wnt signaling pathway-Human papillomavirus infection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia+Pertussis+Human papillomavirus infection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Ribosome-Human papillomavirus infection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Wnt signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Ribosome+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Wnt signaling pathway-Natural killer cell mediated cytotoxicity-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Ribosome-Natural killer cell mediated cytotoxicity-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Wnt signaling pathway+Non-alcoholic fatty liver disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Ribosome+Non-alcoholic fatty liver disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Wnt signaling pathway+Huntington disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Ribosome+Huntington disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Wnt signaling pathway+Parkinson disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Ribosome+Parkinson disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Wnt signaling pathway+Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Coronavirus disease - COVID-19+Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia-Ribosome+Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Akkermansia	IL-6	Akkermansia+Systemic lupus erythematosus-Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.23	0.52	no	no	no	no	no	no	HC
Bifidobacterium	IL-6	Bifidobacterium+TXB2+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.105	0.52	no	dn	no	no	no	no	HC
Bifidobacterium	IL-6	Bifidobacterium+AA+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.105	0.52	no	dn	no	no	no	no	HC
Ruminococcus	IL-6	Ruminococcus+Thermogenesis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.335	0.52	no	no	no	no	no	no	HC
Ruminococcus	IL-6	Ruminococcus-Endocytosis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.335	0.52	no	no	no	no	no	no	HC
Ruminococcus	IL-6	Ruminococcus-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.335	0.52	no	no	no	no	no	no	HC
Ruminococcus	IL-6	Ruminococcus-Biosynthesis of amino acids-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.335	0.52	no	no	no	no	no	no	HC
Ruminococcus	IL-6	Ruminococcus+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.335	0.52	no	no	no	no	no	no	HC
GCDCA+blood	IL-6	GCDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.31	0.52	no	no	no	no	no	no	HC
GCDCA+blood	IL-6	GCDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.31	0.52	no	no	no	no	no	no	HC
GCDCA+blood	IL-6	GCDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.31	0.52	no	no	no	no	no	no	HC
GCDCA+blood	IL-6	GCDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.31	0.52	no	no	no	no	no	no	HC
GCDCA+blood	IL-6	GCDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.31	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]-18:0/22:6-PC+blood-20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]-Glutamatergic synapse-d18:1-22:0-SM+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]+24:0+blood+AA+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]-Aldosterone synthesis and secretion+Alzheimer disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]-18:0/22:6-PC+blood+TXB2+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]-GnRH signaling pathway+Amyotrophic lateral sclerosis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]-Aldosterone synthesis and secretion+Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]-Morphine addiction+Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	"[Prevotella]-Growth hormone synthesis, secretion and action+L-Homocystine+blood+FGF basic+IL-6"	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]-Aldosterone synthesis and secretion+L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]+24:0+blood-L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]-Aldosterone synthesis and secretion+Huntington disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]-Aldosterone synthesis and secretion+Parkinson disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]-GnRH signaling pathway+Parkinson disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]-GnRH signaling pathway+Non-alcoholic fatty liver disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]-Aldosterone synthesis and secretion+Prion disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
[Prevotella]	IL-6	[Prevotella]+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.367	0.52	no	no	no	no	no	no	HC
ACA+blood	IL-6	ACA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.338	0.52	no	no	no	no	no	no	HC
DCA+stool	IL-6	DCA+stool-8-HETE+blood+TXB2+blood-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.195	0.52	no	no	no	no	no	no	HC
DCA+stool	IL-6	DCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.195	0.52	no	no	no	no	no	no	HC
DCA+stool	IL-6	DCA+stool-20:1-LPA+blood-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.195	0.52	no	no	no	no	no	no	HC
DCA+stool	IL-6	DCA+stool-8-HETE+blood-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.195	0.52	no	no	no	no	no	no	HC
DCA+stool	IL-6	DCA+stool-8-HETE+blood+AA+blood-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.195	0.52	no	no	no	no	no	no	HC
DCA+stool	IL-6	DCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.195	0.52	no	no	no	no	no	no	HC
DCA+stool	IL-6	DCA+stool-DL-methionine sulfoxide+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.195	0.52	no	no	no	no	no	no	HC
2-hydroxyhippuric acid+urine	IL-6	2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-6	Indirect	urine_cometabolism	serum_cytokines	0.215	0.52	no	no	no	no	no	no	HC
Butyric acid+stool	IL-6	Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic+IL-6	Indirect	stool_scfa	serum_cytokines	0.102	0.52	dn	no	no	no	no	no	HC
4-hydroxybenzoic acid+stool	IL-6	4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.52	no	dn	no	no	no	no	HC
GCA+blood	IL-6	GCA+blood+TCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.16	0.52	no	no	no	no	no	no	HC
GCA+blood	IL-6	GCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.16	0.52	no	no	no	no	no	no	HC
GCA+blood	IL-6	GCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.16	0.52	no	no	no	no	no	no	HC
GCA+blood	IL-6	GCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.16	0.52	no	no	no	no	no	no	HC
ACA+stool	IL-6	ACA+stool+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.417	0.52	no	no	no	no	no	no	HC
ACA+stool	IL-6	ACA+stool-Acetic acid+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.417	0.52	no	no	no	no	no	no	HC
CDCA+blood	IL-6	CDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.506	0.52	no	no	no	no	no	no	HC
capric acid C6+blood	IL-6	capric acid C6+blood-Cystine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.433	0.52	no	no	no	no	no	no	HC
capric acid C6+blood	IL-6	capric acid C6+blood-Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.433	0.52	no	no	no	no	no	no	HC
capric acid C6+blood	IL-6	capric acid C6+blood-Cystine+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.433	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-Lysosome+Phagosome-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-UFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-18:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-16:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-16:0/20:3-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-18:1/18:1-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-SFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-16:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-18:1/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella+18:0/18:1-PE+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-24:1+blood-d18:1-22:0-SM+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella+12-ketoDCA+blood-AA+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-16:1/16:0-PC+blood+AA+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-16:1/16:1-PC+blood+AA+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Human papillomavirus infection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Viral carcinogenesis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella+Estrogen signaling pathway-Viral carcinogenesis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-Lysosome+Viral carcinogenesis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella+18:1-LPE+blood+L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-18:1/18:1-PC+blood+20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella+18:1-LPE+blood-TXB2+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella+Estrogen signaling pathway-Autoimmune thyroid disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella+Estrogen signaling pathway-Allograft rejection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella+Estrogen signaling pathway-Graft-versus-host disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella+Estrogen signaling pathway-Type I diabetes mellitus-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella+Estrogen signaling pathway-Viral myocarditis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-16:0/16:0-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-Lysosome+Endocytosis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
Prevotella	IL-6	Prevotella-Lysosome+Natural killer cell mediated cytotoxicity-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.287	0.52	no	no	no	no	no	no	HC
TCA+blood	IL-6	TCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.339	0.52	no	no	no	no	no	no	HC
iso-DCA+blood	IL-6	iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.38	0.52	no	no	no	no	no	no	HC
HCA+stool	IL-6	HCA+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.155	0.52	no	no	no	no	no	no	HC
Roseburia	IL-6	Roseburia-L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.495	0.52	no	no	no	no	no	no	HC
Roseburia	IL-6	Roseburia+TXB2+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.495	0.52	no	no	no	no	no	no	HC
12-ketoDCA+stool	IL-6	12-ketoDCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.505	0.52	no	no	no	no	no	no	HC
12-ketoDCA+stool	IL-6	12-ketoDCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.505	0.52	no	no	no	no	no	no	HC
GLCA+blood	IL-6	GLCA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.319	0.52	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-6	L-Tryptophan+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.557	0.52	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-6	L-Tryptophan+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.557	0.52	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-6	L-Tryptophan+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.557	0.52	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-6	L-Tryptophan+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.557	0.52	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-6	L-Tryptophan+stool-12-ketoDCA+blood-AA+blood-FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.557	0.52	no	no	no	no	no	no	HC
CA+blood	IL-6	CA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.606	0.52	no	no	no	no	no	no	HC
GUDCA+stool	IL-6	GUDCA+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0085	0.52	no	dn	no	no	no	no	HC
GUDCA+stool	IL-6	GUDCA+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0085	0.52	no	dn	no	no	no	no	HC
L-Phenylalanine+stool	IL-6	L-Phenylalanine+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.398	0.52	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IL-6	L-Phenylalanine+stool-12-ketoDCA+blood-AA+blood-FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.398	0.52	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IL-6	L-Phenylalanine+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.398	0.52	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IL-6	L-Phenylalanine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.398	0.52	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IL-6	L-Phenylalanine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.398	0.52	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-6	butyric acid C4+blood+Cystine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.407	0.52	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-6	butyric acid C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.407	0.52	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-6	butyric acid C4+blood+Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.407	0.52	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-6	butyric acid C4+blood+Cystine+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.407	0.52	no	no	no	no	no	no	HC
GCA+stool	IL-6	GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	HC
GCA+stool	IL-6	GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	HC
GCA+stool	IL-6	GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	HC
GCA+stool	IL-6	GCA+stool+18:0/22:6-PE+blood-20:0+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	HC
GCA+stool	IL-6	GCA+stool+GDCA+stool-TXB2+blood-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	HC
GCA+stool	IL-6	GCA+stool-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0809	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus-18:1/18:2-PG+blood+AA+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus-Lysosome+Viral carcinogenesis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Ribosome biogenesis in eukaryotes-Viral carcinogenesis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus-Influenza A+Viral carcinogenesis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+TCA+stool-20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Primary immunodeficiency-20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Central carbon metabolism in cancer-20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Lachnospira-20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus-18:1-LPC+blood+20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus-Phenylacetic acid+stool+20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus-18:2-LPC+blood+20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Primary immunodeficiency-Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Lachnospira-L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus-18:1-LPC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus-Lysosome+Endocytosis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Ribosome biogenesis in eukaryotes-Endocytosis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus-Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Ribosome biogenesis in eukaryotes-Allograft rejection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus-Influenza A+Allograft rejection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Ribosome biogenesis in eukaryotes-Cell adhesion molecules-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Ribosome biogenesis in eukaryotes-Autoimmune thyroid disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus-Influenza A+Autoimmune thyroid disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Ribosome biogenesis in eukaryotes-Cellular senescence-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus-Lysosome+Natural killer cell mediated cytotoxicity-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Ribosome biogenesis in eukaryotes-Natural killer cell mediated cytotoxicity-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Ribosome biogenesis in eukaryotes-Graft-versus-host disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus-Influenza A+Graft-versus-host disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Ribosome biogenesis in eukaryotes-Human papillomavirus infection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus-Influenza A+Human papillomavirus infection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Ribosome biogenesis in eukaryotes+mRNA surveillance pathway+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus-Lysosome+Phagosome-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Ribosome biogenesis in eukaryotes-Phagosome-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Ribosome biogenesis in eukaryotes+RNA degradation+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Ribosome biogenesis in eukaryotes-Type I diabetes mellitus-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus+Ribosome biogenesis in eukaryotes-Viral myocarditis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Coprococcus	IL-6	Coprococcus-Influenza A+Viral myocarditis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.612	0.52	no	no	no	no	no	no	HC
Oscillospira	IL-6	Oscillospira-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.62	0.52	no	no	no	no	no	no	HC
Oscillospira	IL-6	Oscillospira+L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.62	0.52	no	no	no	no	no	no	HC
HCA+blood	IL-6	HCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.544	0.52	no	no	no	no	no	no	HC
iso-LCA+stool	IL-6	iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	HC
iso-LCA+stool	IL-6	iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	HC
iso-LCA+stool	IL-6	iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	HC
iso-LCA+stool	IL-6	iso-LCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	HC
iso-LCA+stool	IL-6	iso-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	HC
iso-LCA+stool	IL-6	iso-LCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.72	0.52	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-6	2-methyl-butyric acid m-C4+blood+20:1+blood-22:6n3+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.262	0.52	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-6	2-methyl-butyric acid m-C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.262	0.52	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-6	2-methyl-butyric acid m-C4+blood+decanoic acid C10+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.262	0.52	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-6	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.262	0.52	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-6	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.262	0.52	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-6	2-methyl-butyric acid m-C4+blood-22:2-LPA+blood-d18:0-24:1-SM+blood+d18:1-22:0-SM+blood+FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.262	0.52	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-6	2-methyl-butyric acid m-C4+blood+20:1+blood+20:1-LPC+blood-TXB2+blood-FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.262	0.52	no	no	no	no	no	no	HC
DCA+blood	IL-6	DCA+blood+GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.122	0.52	no	no	no	no	no	no	HC
DCA+blood	IL-6	DCA+blood+GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.122	0.52	no	no	no	no	no	no	HC
DCA+blood	IL-6	DCA+blood+GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.122	0.52	no	no	no	no	no	no	HC
DCA+blood	IL-6	DCA+blood+GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.122	0.52	no	no	no	no	no	no	HC
DCA+blood	IL-6	DCA+blood+GUDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.122	0.52	no	no	no	no	no	no	HC
DCA+blood	IL-6	DCA+blood+GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.122	0.52	no	no	no	no	no	no	HC
DCA+blood	IL-6	"DCA+blood-n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-6"	Indirect	serum_bileacids	serum_cytokines	0.122	0.52	no	no	no	no	no	no	HC
DCA+blood	IL-6	DCA+blood+GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.122	0.52	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-6	3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.33	0.52	no	no	no	no	no	no	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-6	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-6"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.52	up	up	no	no	no	no	HC
GLCA+stool	IL-6	GLCA+stool-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.617	0.52	no	no	no	no	no	no	HC
GLCA+stool	IL-6	GLCA+stool-iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.617	0.52	no	no	no	no	no	no	HC
GLCA+stool	IL-6	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.617	0.52	no	no	no	no	no	no	HC
GLCA+stool	IL-6	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.617	0.52	no	no	no	no	no	no	HC
GLCA+stool	IL-6	GLCA+stool-iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.617	0.52	no	no	no	no	no	no	HC
GLCA+stool	IL-6	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.617	0.52	no	no	no	no	no	no	HC
GLCA+stool	IL-6	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.617	0.52	no	no	no	no	no	no	HC
GLCA+stool	IL-6	GLCA+stool-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.617	0.52	no	no	no	no	no	no	HC
GLCA+stool	IL-6	GLCA+stool-iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.617	0.52	no	no	no	no	no	no	HC
GLCA+stool	IL-6	"GLCA+stool-LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+FGF basic+IL-6"	Indirect	stool_bileacids	serum_cytokines	0.617	0.52	no	no	no	no	no	no	HC
GLCA+stool	IL-6	GLCA+stool-iso-LCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.617	0.52	no	no	no	no	no	no	HC
GLCA+stool	IL-6	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.617	0.52	no	no	no	no	no	no	HC
GLCA+stool	IL-6	GLCA+stool-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.617	0.52	no	no	no	no	no	no	HC
GLCA+stool	IL-6	GLCA+stool-iso-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.617	0.52	no	no	no	no	no	no	HC
GLCA+stool	IL-6	GLCA+stool-LCA+stool-TCA+stool-20:0+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.617	0.52	no	no	no	no	no	no	HC
GLCA+stool	IL-6	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.617	0.52	no	no	no	no	no	no	HC
GLCA+stool	IL-6	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.617	0.52	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-6	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.304	0.52	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-6	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.304	0.52	no	no	no	no	no	no	HC
TCA+stool	IL-6	TCA+stool-20:0+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.458	0.52	no	no	no	no	no	no	HC
HDCA+stool	IL-6	HDCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	HC
HDCA+stool	IL-6	HDCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	HC
HDCA+stool	IL-6	HDCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	HC
HDCA+stool	IL-6	HDCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	HC
HDCA+stool	IL-6	HDCA+stool+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	HC
HDCA+stool	IL-6	HDCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	HC
HDCA+stool	IL-6	HDCA+stool+16:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	HC
HDCA+stool	IL-6	HDCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	HC
HDCA+stool	IL-6	HDCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	HC
HDCA+stool	IL-6	HDCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	HC
HDCA+stool	IL-6	HDCA+stool+20:3/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.176	0.52	no	no	no	no	no	no	HC
Lachnospira	IL-6	Lachnospira-L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	HC
Lachnospira	IL-6	Lachnospira-20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.279	0.52	no	no	no	no	no	no	HC
isobutyric acid C4+blood	IL-6	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.0151	0.52	up	up	no	no	no	no	HC
isobutyric acid C4+blood	IL-6	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.0151	0.52	up	up	no	no	no	no	HC
isobutyric acid C4+blood	IL-6	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.0151	0.52	up	up	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool-9-HODE+blood-L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood+TXB2+blood-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood-TXB2+blood-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood-20:0+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool-Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool-9-HODE+blood+GPC+blood-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood+L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool+18:0/20:5-PC+blood-20:0-LPE+blood+d18:1-22:0-SM+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool+18:0/20:5-PC+blood+18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool+18:0/20:5-PC+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool+18:0/20:5-PC+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool+18:0/20:5-PC+blood+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool+18:0/20:5-PC+blood+18:1/18:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
GCDCA+stool	IL-6	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.0471	0.52	no	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool+GCA+stool-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool+GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool+GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool+GCA+stool+GDCA+stool-TXB2+blood-FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-6	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-20:0+blood+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.52	dn	dn	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Endocrine resistance+Huntington disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Long-term depression+Huntington disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Pancreatic secretion+Huntington disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Aldosterone synthesis and secretion+Huntington disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Cushing syndrome+Huntington disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Endocrine resistance+L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Long-term depression+L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Pancreatic secretion+L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Aldosterone synthesis and secretion+L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter+Arginine and proline metabolism+Biosynthesis of amino acids-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Endocrine resistance+mRNA surveillance pathway+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Long-term depression-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Pancreatic secretion-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Long-term depression+Prion disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Pancreatic secretion+Prion disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Aldosterone synthesis and secretion+Prion disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Endocrine resistance+Non-alcoholic fatty liver disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Long-term depression+Non-alcoholic fatty liver disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Endocrine resistance+Parkinson disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Long-term depression+Parkinson disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter+Arginine and proline metabolism-Parkinson disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Pancreatic secretion+Parkinson disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Aldosterone synthesis and secretion+Parkinson disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Cushing syndrome+Parkinson disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Endocrine resistance+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Long-term depression+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter+Arginine and proline metabolism-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Pancreatic secretion+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Cushing syndrome+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Endocrine resistance+RNA degradation+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter+Arginine and proline metabolism-RNA degradation+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Endocrine resistance+Alzheimer disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Long-term depression+Alzheimer disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Pancreatic secretion+Alzheimer disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Aldosterone synthesis and secretion+Alzheimer disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Cushing syndrome+Alzheimer disease+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Phospholipase D signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Endocrine resistance+Thermogenesis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter+Arginine and proline metabolism-Thermogenesis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Endocrine resistance+Amyotrophic lateral sclerosis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Long-term depression+Amyotrophic lateral sclerosis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter+Arginine and proline metabolism-Amyotrophic lateral sclerosis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Pancreatic secretion+Amyotrophic lateral sclerosis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Cushing syndrome+Amyotrophic lateral sclerosis+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Pancreatic secretion+20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Morphine addiction+Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Long-term depression+Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Pancreatic secretion+Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Aldosterone synthesis and secretion+Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Odoribacter	IL-6	Odoribacter-Cushing syndrome+Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.798	0.52	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-6	Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-6	Indirect	stool_scfa	serum_cytokines	0.408	0.52	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-6	Isobutyric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_scfa	serum_cytokines	0.408	0.52	no	no	no	no	no	no	HC
Kynurenic acid+stool	IL-6	Kynurenic acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.037	0.52	dn	dn	no	no	no	no	HC
L-Tryptophan+urine	IL-6	L-Tryptophan+urine+FGF basic+IL-6	Indirect	urine_cometabolism	serum_cytokines	0.226	0.52	no	no	no	no	no	no	HC
Eggerthella	IL-6	Eggerthella+Bacteroides-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.912	0.52	no	no	no	no	no	no	HC
Anaerotruncus	IL-6	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	HC
Anaerotruncus	IL-6	Anaerotruncus-Gemmiger-Tuberculosis+Graft-versus-host disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	HC
Anaerotruncus	IL-6	Anaerotruncus-Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	HC
Anaerotruncus	IL-6	Anaerotruncus-Gemmiger-Tuberculosis-Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	HC
Anaerotruncus	IL-6	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Viral myocarditis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	HC
Anaerotruncus	IL-6	Anaerotruncus-Gemmiger-Tuberculosis+Viral myocarditis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	HC
Anaerotruncus	IL-6	Anaerotruncus-Gemmiger-GPC+blood-L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	HC
Anaerotruncus	IL-6	Anaerotruncus-Gemmiger-20:1-LPA+blood-L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	HC
Anaerotruncus	IL-6	Anaerotruncus-Gemmiger-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	HC
Anaerotruncus	IL-6	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Allograft rejection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	HC
Anaerotruncus	IL-6	Anaerotruncus-Gemmiger-Tuberculosis+Allograft rejection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	HC
Anaerotruncus	IL-6	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	HC
Anaerotruncus	IL-6	Anaerotruncus-Gemmiger-Tuberculosis+Autoimmune thyroid disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	HC
Anaerotruncus	IL-6	Anaerotruncus-Gemmiger+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	HC
Anaerotruncus	IL-6	Anaerotruncus-Gemmiger-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.904	0.52	no	no	no	no	no	no	HC
Anaerostipes	IL-6	Anaerostipes-20:0+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.568	0.52	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-6	Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_scfa	serum_cytokines	0.343	0.52	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-6	Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-6	Indirect	stool_scfa	serum_cytokines	0.343	0.52	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-6	Isovaleric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_scfa	serum_cytokines	0.343	0.52	no	no	no	no	no	no	HC
Paraprevotella	IL-6	Paraprevotella-L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	HC
Paraprevotella	IL-6	Paraprevotella+AA+blood-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.118	0.52	no	no	no	no	no	no	HC
Homovanillic acid+urine	IL-6	Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-6	Indirect	urine_cometabolism	serum_cytokines	0.45	0.52	no	no	no	no	no	no	HC
Homovanillic acid+urine	IL-6	Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	urine_cometabolism	serum_cytokines	0.45	0.52	no	no	no	no	no	no	HC
TDCA+blood	IL-6	TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.155	0.52	no	up	no	no	no	no	HC
iso-LCA+blood	IL-6	iso-LCA+blood-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.507	0.52	no	no	no	no	no	no	HC
iso-LCA+blood	IL-6	iso-LCA+blood-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.507	0.52	no	no	no	no	no	no	HC
iso-LCA+blood	IL-6	iso-LCA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.507	0.52	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IL-6	¦Ø-MCA+stool-Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.919	0.52	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IL-6	¦Ø-MCA+stool-Acetic acid+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.919	0.52	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-6	Phenylacetic acid+stool+20:0+blood+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.785	0.52	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-6	Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.785	0.52	no	no	no	no	no	no	HC
Gemmiger	IL-6	Gemmiger-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	HC
Gemmiger	IL-6	Gemmiger-Tuberculosis+Graft-versus-host disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	HC
Gemmiger	IL-6	Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	HC
Gemmiger	IL-6	Gemmiger-Tuberculosis-Diabetic cardiomyopathy+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	HC
Gemmiger	IL-6	Gemmiger-Staphylococcus aureus infection+Viral myocarditis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	HC
Gemmiger	IL-6	Gemmiger-Tuberculosis+Viral myocarditis-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	HC
Gemmiger	IL-6	Gemmiger-GPC+blood-L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	HC
Gemmiger	IL-6	Gemmiger-20:1-LPA+blood-L-Homocystine+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	HC
Gemmiger	IL-6	Gemmiger-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	HC
Gemmiger	IL-6	Gemmiger-Staphylococcus aureus infection+Allograft rejection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	HC
Gemmiger	IL-6	Gemmiger-Tuberculosis+Allograft rejection-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	HC
Gemmiger	IL-6	Gemmiger-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	HC
Gemmiger	IL-6	Gemmiger-Tuberculosis+Autoimmune thyroid disease-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	HC
Gemmiger	IL-6	Gemmiger+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	HC
Gemmiger	IL-6	Gemmiger-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.595	0.52	no	no	no	no	no	no	HC
GDCA+stool	IL-6	GDCA+stool-TXB2+blood-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.656	0.52	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-6	L-Tyrosine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.44	0.52	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-6	L-Tyrosine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.44	0.52	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-6	L-Tyrosine+stool+PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.44	0.52	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-6	L-Tyrosine+stool+20:1-LPA+blood-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.44	0.52	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-6	L-Tyrosine+stool+8-HETE+blood-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.44	0.52	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-6	L-Tyrosine+stool-12-ketoDCA+blood-AA+blood-FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.44	0.52	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-6	L-Tyrosine+stool+8-HETE+blood+AA+blood-FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.44	0.52	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-6	L-Tyrosine+stool+8-HETE+blood+TXB2+blood-FGF basic+IL-6	Indirect	stool_cometabolism	serum_cytokines	0.44	0.52	no	no	no	no	no	no	HC
CDCA+stool	IL-6	CDCA+stool+18:3n3+blood+AA+blood-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.663	0.52	no	no	no	no	no	no	HC
CDCA+stool	IL-6	CDCA+stool+TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.663	0.52	no	no	no	no	no	no	HC
CDCA+stool	IL-6	CDCA+stool+nutriCA+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.663	0.52	no	no	no	no	no	no	HC
CDCA+stool	IL-6	CDCA+stool+HCA+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.663	0.52	no	no	no	no	no	no	HC
CDCA+stool	IL-6	CDCA+stool+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.663	0.52	no	no	no	no	no	no	HC
CDCA+stool	IL-6	CDCA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.663	0.52	no	no	no	no	no	no	HC
CDCA+stool	IL-6	CDCA+stool-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.663	0.52	no	no	no	no	no	no	HC
CA+stool	IL-6	CA+stool+nutriCA+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.827	0.52	no	no	no	no	no	no	HC
CA+stool	IL-6	CA+stool+HCA+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.827	0.52	no	no	no	no	no	no	HC
CA+stool	IL-6	CA+stool-ACA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.827	0.52	no	no	no	no	no	no	HC
CA+stool	IL-6	CA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.827	0.52	no	no	no	no	no	no	HC
CA+stool	IL-6	CA+stool+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.827	0.52	no	no	no	no	no	no	HC
CA+stool	IL-6	CA+stool-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.827	0.52	no	no	no	no	no	no	HC
CA+stool	IL-6	CA+stool+GDCA+stool-TXB2+blood-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.827	0.52	no	no	no	no	no	no	HC
CA+stool	IL-6	CA+stool+TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.827	0.52	no	no	no	no	no	no	HC
CA+stool	IL-6	CA+stool-18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.827	0.52	no	no	no	no	no	no	HC
HDCA+blood	IL-6	HDCA+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.483	0.52	no	no	no	no	no	no	HC
HDCA+blood	IL-6	HDCA+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.483	0.52	no	no	no	no	no	no	HC
HDCA+blood	IL-6	HDCA+blood+SFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.483	0.52	no	no	no	no	no	no	HC
HDCA+blood	IL-6	HDCA+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.483	0.52	no	no	no	no	no	no	HC
UDCA+stool	IL-6	UDCA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.266	0.52	no	no	no	no	no	no	HC
UDCA+stool	IL-6	UDCA+stool+18:3n3+blood+AA+blood-FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.266	0.52	no	no	no	no	no	no	HC
LCA+blood	IL-6	LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.884	0.52	no	no	no	no	no	no	HC
nutriCA+stool	IL-6	nutriCA+stool-L-Homocystine+blood+FGF basic+IL-6	Indirect	stool_bileacids	serum_cytokines	0.481	0.52	no	no	no	no	no	no	HC
GDCA+blood	IL-6	GDCA+blood+TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.632	0.52	no	no	no	no	no	no	HC
P-hydroxyhippuric acid+urine	IL-6	P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	urine_cometabolism	serum_cytokines	0.436	0.52	no	no	no	no	no	no	HC
acetic acid C2+blood	IL-6	acetic acid C2+blood-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.000193	0.52	up	dn	no	no	no	no	HC
isovaleric acid iso-C5+blood	IL-6	isovaleric acid iso-C5+blood+Sarcosine+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-6	Indirect	serum_scfa	serum_cytokines	0.117	0.52	no	no	no	no	no	no	HC
L-Phenylalanine+urine	IL-6	L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-6	Indirect	urine_cometabolism	serum_cytokines	0.0908	0.52	no	up	no	no	no	no	HC
Clostridium	IL-6	Clostridium+P-hydroxyhippuric acid+urine-FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	HC
Clostridium	IL-6	Clostridium-L-Tryptophan+urine+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.925	0.52	no	no	no	no	no	no	HC
12-ketoDCA+blood	IL-6	12-ketoDCA+blood-AA+blood-FGF basic+IL-6	Indirect	serum_bileacids	serum_cytokines	0.517	0.52	no	no	no	no	no	no	HC
Butyricicoccus	IL-6	Butyricicoccus+d18:1-22:0-SM+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.852	0.52	no	no	no	no	no	no	HC
3-Hydroxy-L-kynurenine+urine	IL-6	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine+FGF basic+IL-6	Indirect	urine_cometabolism	serum_cytokines	0.401	0.52	no	no	no	no	no	no	HC
Wautersiella	IL-6	Wautersiella+Butyricicoccus+d18:1-22:0-SM+blood+FGF basic+IL-6	Indirect	Genus	serum_cytokines	0.289	0.52	no	no	no	no	no	no	HC
Blautia	IL-13	Blautia+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	1.36E-05	0.00264	up	dn	dn	up	up	no	HC
Parabacteroides	IL-13	Parabacteroides+Biosynthesis of amino acids-FGF basic-IL-13	Indirect	Genus	serum_cytokines	4.19E-05	0.00264	no	up	up	up	up	no	HC
Parabacteroides	IL-13	Parabacteroides-RNA degradation+FGF basic-IL-13	Indirect	Genus	serum_cytokines	4.19E-05	0.00264	no	up	up	up	up	no	HC
Parabacteroides	IL-13	Parabacteroides-mRNA surveillance pathway+FGF basic-IL-13	Indirect	Genus	serum_cytokines	4.19E-05	0.00264	no	up	up	up	up	no	HC
Dorea	IL-13	Dorea-VEGF signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Fc epsilon RI signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-18:2-LPC+blood+20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Endocrine resistance+Huntington disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Endocrine resistance+L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Chemical carcinogenesis - receptor activation+L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	"Dorea-Growth hormone synthesis, secretion and action+L-Homocystine+blood+FGF basic-IL-13"	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Endocrine resistance+mRNA surveillance pathway+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Endocrine resistance+Non-alcoholic fatty liver disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-GnRH signaling pathway+Non-alcoholic fatty liver disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Endocrine resistance+Parkinson disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-GnRH signaling pathway+Parkinson disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Endocrine resistance+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Endocrine resistance+RNA degradation+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Endocrine resistance+Thermogenesis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Thyroid hormone signaling pathway+Viral myocarditis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Chemical carcinogenesis - receptor activation-Viral myocarditis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-16:0-LPC+blood+AA+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Amphetamine addiction-Human papillomavirus infection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Amphetamine addiction-Autoimmune thyroid disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Chemical carcinogenesis - receptor activation-Autoimmune thyroid disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-16:0-LPC+blood+TXB2+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Amphetamine addiction-Allograft rejection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Chemical carcinogenesis - receptor activation-Allograft rejection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Amphetamine addiction-Graft-versus-host disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Chemical carcinogenesis - receptor activation-Graft-versus-host disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea+Legionellosis-Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Amphetamine addiction+Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Chemical carcinogenesis - receptor activation+Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Amphetamine addiction-Viral carcinogenesis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Endocrine resistance+Amyotrophic lateral sclerosis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-GnRH signaling pathway+Amyotrophic lateral sclerosis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Chemical carcinogenesis - receptor activation-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Dorea	IL-13	Dorea-Endocrine resistance+Alzheimer disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.00362	0.00264	up	no	dn	up	up	no	HC
Faecalibacterium	IL-13	Faecalibacterium+Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0039	0.00264	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-13	Faecalibacterium-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0039	0.00264	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-13	Faecalibacterium-Staphylococcus aureus infection+Viral myocarditis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0039	0.00264	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-13	Faecalibacterium-Staphylococcus aureus infection+Allograft rejection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0039	0.00264	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-13	Faecalibacterium-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0039	0.00264	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-13	Faecalibacterium+4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0039	0.00264	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-13	Faecalibacterium-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0039	0.00264	no	dn	dn	up	up	no	HC
TUDCA+blood	IL-13	TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.0282	0.00264	no	no	dn	up	up	no	HC
TUDCA+blood	IL-13	TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.0282	0.00264	no	no	dn	up	up	no	HC
isocapric acid iso-C6+blood	IL-13	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.0458	0.00264	no	no	dn	up	up	no	HC
Bacteroides	IL-13	Bacteroides-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.000267	0.00264	dn	dn	up	up	up	no	HC
Propionic acid+stool	IL-13	Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_scfa	serum_cytokines	0.0436	0.00264	dn	no	up	up	up	no	HC
Propionic acid+stool	IL-13	Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_scfa	serum_cytokines	0.0436	0.00264	dn	no	up	up	up	no	HC
Propionic acid+stool	IL-13	Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_scfa	serum_cytokines	0.0436	0.00264	dn	no	up	up	up	no	HC
Propionic acid+stool	IL-13	Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_scfa	serum_cytokines	0.0436	0.00264	dn	no	up	up	up	no	HC
Propionic acid+stool	IL-13	Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic-IL-13	Indirect	stool_scfa	serum_cytokines	0.0436	0.00264	dn	no	up	up	up	no	HC
[Ruminococcus]	IL-13	[Ruminococcus]+nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0679	0.00264	no	no	dn	up	up	no	HC
[Ruminococcus]	IL-13	[Ruminococcus]+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0679	0.00264	no	no	dn	up	up	no	HC
[Ruminococcus]	IL-13	[Ruminococcus]-Hypotaurine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0679	0.00264	no	no	dn	up	up	no	HC
GUDCA+blood	IL-13	GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00264	no	no	dn	up	up	no	HC
GUDCA+blood	IL-13	GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00264	no	no	dn	up	up	no	HC
GUDCA+blood	IL-13	GUDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00264	no	no	dn	up	up	no	HC
GUDCA+blood	IL-13	GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00264	no	no	dn	up	up	no	HC
GUDCA+blood	IL-13	GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00264	no	no	dn	up	up	no	HC
GUDCA+blood	IL-13	GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00264	no	no	dn	up	up	no	HC
GUDCA+blood	IL-13	GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00264	no	no	dn	up	up	no	HC
Acetic acid+stool	IL-13	Acetic acid+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_scfa	serum_cytokines	0.0656	0.00264	dn	no	no	up	up	no	HC
Alistipes	IL-13	Alistipes+SFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes+20:3/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes+16:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-GDCA+stool-TXB2+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-MAPK signaling pathway-Cell adhesion molecules-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Lipid and atherosclerosis+AA+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Progesterone-mediated oocyte maturation-Allograft rejection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-MAPK signaling pathway-Allograft rejection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Peroxisome-Cardiac muscle contraction+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Peroxisome-Alzheimer disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Progesterone-mediated oocyte maturation-Autoimmune thyroid disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-MAPK signaling pathway-Autoimmune thyroid disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Peroxisome-Prion disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Peroxisome-Huntington disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Progesterone-mediated oocyte maturation-Viral myocarditis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Autophagy - animal-Viral myocarditis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-MAPK signaling pathway-Viral myocarditis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Cholinergic synapse-Viral myocarditis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Peroxisome+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Peroxisome-Non-alcoholic fatty liver disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Peroxisome-Thermogenesis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-NOD-like receptor signaling pathway-Thermogenesis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Autophagy - animal+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-GABAergic synapse+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-FoxO signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Peroxisome+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Autophagy - animal+L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-GABAergic synapse-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-FoxO signaling pathway-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Peroxisome-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-NOD-like receptor signaling pathway-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Olfactory transduction-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Primary immunodeficiency-Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Peroxisome-Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Primary immunodeficiency-20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-16:0/18:2-PI+blood-20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Central carbon metabolism in cancer-20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Peroxisome-20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Olfactory transduction-20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Progesterone-mediated oocyte maturation-Type I diabetes mellitus-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-MAPK signaling pathway-Type I diabetes mellitus-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-GABAergic synapse-Amyotrophic lateral sclerosis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Peroxisome-Amyotrophic lateral sclerosis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-NOD-like receptor signaling pathway-Amyotrophic lateral sclerosis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Progesterone-mediated oocyte maturation-Graft-versus-host disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-MAPK signaling pathway-Graft-versus-host disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-GABAergic synapse-Parkinson disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-Peroxisome-Parkinson disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Alistipes	IL-13	Alistipes-NOD-like receptor signaling pathway-Parkinson disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.0114	0.00264	no	up	no	up	up	no	HC
Butyricimonas	IL-13	Butyricimonas+Prion disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.17	0.00264	no	no	no	up	up	no	HC
Butyricimonas	IL-13	Butyricimonas+Non-alcoholic fatty liver disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.17	0.00264	no	no	no	up	up	no	HC
Butyricimonas	IL-13	Butyricimonas+Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.17	0.00264	no	no	no	up	up	no	HC
Collinsella	IL-13	Collinsella-L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.128	0.00264	no	no	no	up	up	no	HC
iso-DCA+stool	IL-13	iso-DCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.155	0.00264	no	no	no	up	up	no	HC
LCA+stool	IL-13	"LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+FGF basic-IL-13"	Indirect	stool_bileacids	serum_cytokines	0.314	0.00264	no	no	no	up	up	no	HC
LCA+stool	IL-13	LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.314	0.00264	no	no	no	up	up	no	HC
LCA+stool	IL-13	LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.314	0.00264	no	no	no	up	up	no	HC
LCA+stool	IL-13	LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.314	0.00264	no	no	no	up	up	no	HC
LCA+stool	IL-13	LCA+stool-TCA+stool-20:0+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.314	0.00264	no	no	no	up	up	no	HC
LCA+stool	IL-13	LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.314	0.00264	no	no	no	up	up	no	HC
LCA+stool	IL-13	LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.314	0.00264	no	no	no	up	up	no	HC
LCA+stool	IL-13	LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.314	0.00264	no	no	no	up	up	no	HC
LCA+stool	IL-13	LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.314	0.00264	no	no	no	up	up	no	HC
LCA+stool	IL-13	LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.314	0.00264	no	no	no	up	up	no	HC
LCA+stool	IL-13	LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.314	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia+Systemic lupus erythematosus+Graft-versus-host disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Ribosome-Phagosome-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Ribosome+Cardiac muscle contraction+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Wnt signaling pathway+Retrograde endocannabinoid signaling+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Wnt signaling pathway+Prion disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Ribosome+Prion disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Ribosome-Endocytosis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Wnt signaling pathway+Thermogenesis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Ribosome+Thermogenesis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Wnt signaling pathway+Alzheimer disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Ribosome+Alzheimer disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Ribosome+mRNA surveillance pathway+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Wnt signaling pathway+Amyotrophic lateral sclerosis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Ribosome+Amyotrophic lateral sclerosis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia+Pertussis+16:0/22:6-PC+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia+Systemic lupus erythematosus+Allograft rejection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Ribosome+RNA degradation+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Acetic acid+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Wnt signaling pathway-Cell adhesion molecules-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Ribosome-Cell adhesion molecules-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Wnt signaling pathway-Human papillomavirus infection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia+Pertussis+Human papillomavirus infection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Ribosome-Human papillomavirus infection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Wnt signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Ribosome+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Wnt signaling pathway-Natural killer cell mediated cytotoxicity-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Ribosome-Natural killer cell mediated cytotoxicity-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Wnt signaling pathway+Non-alcoholic fatty liver disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Ribosome+Non-alcoholic fatty liver disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Wnt signaling pathway+Huntington disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Ribosome+Huntington disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Wnt signaling pathway+Parkinson disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Ribosome+Parkinson disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Wnt signaling pathway+Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Coronavirus disease - COVID-19+Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia-Ribosome+Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Akkermansia	IL-13	Akkermansia+Systemic lupus erythematosus-Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.23	0.00264	no	no	no	up	up	no	HC
Bifidobacterium	IL-13	Bifidobacterium+TXB2+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.105	0.00264	no	dn	no	up	up	no	HC
Bifidobacterium	IL-13	Bifidobacterium+AA+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.105	0.00264	no	dn	no	up	up	no	HC
Ruminococcus	IL-13	Ruminococcus+Thermogenesis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	HC
Ruminococcus	IL-13	Ruminococcus-Endocytosis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	HC
Ruminococcus	IL-13	Ruminococcus-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	HC
Ruminococcus	IL-13	Ruminococcus-Biosynthesis of amino acids-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	HC
Ruminococcus	IL-13	Ruminococcus+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.335	0.00264	no	no	no	up	up	no	HC
GCDCA+blood	IL-13	GCDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.31	0.00264	no	no	no	up	up	no	HC
GCDCA+blood	IL-13	GCDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.31	0.00264	no	no	no	up	up	no	HC
GCDCA+blood	IL-13	GCDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.31	0.00264	no	no	no	up	up	no	HC
GCDCA+blood	IL-13	GCDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.31	0.00264	no	no	no	up	up	no	HC
GCDCA+blood	IL-13	GCDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.31	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]-18:0/22:6-PC+blood-20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]-Glutamatergic synapse-d18:1-22:0-SM+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]+24:0+blood+AA+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]-Aldosterone synthesis and secretion+Alzheimer disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]-18:0/22:6-PC+blood+TXB2+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]-GnRH signaling pathway+Amyotrophic lateral sclerosis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]-Aldosterone synthesis and secretion+Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]-Morphine addiction+Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	"[Prevotella]-Growth hormone synthesis, secretion and action+L-Homocystine+blood+FGF basic-IL-13"	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]-Aldosterone synthesis and secretion+L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]+24:0+blood-L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]-Aldosterone synthesis and secretion+Huntington disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]-Aldosterone synthesis and secretion+Parkinson disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]-GnRH signaling pathway+Parkinson disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]-GnRH signaling pathway+Non-alcoholic fatty liver disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]-Aldosterone synthesis and secretion+Prion disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
[Prevotella]	IL-13	[Prevotella]+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.367	0.00264	no	no	no	up	up	no	HC
ACA+blood	IL-13	ACA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.338	0.00264	no	no	no	up	up	no	HC
DCA+stool	IL-13	DCA+stool-8-HETE+blood+TXB2+blood-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.195	0.00264	no	no	no	up	up	no	HC
DCA+stool	IL-13	DCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.195	0.00264	no	no	no	up	up	no	HC
DCA+stool	IL-13	DCA+stool-20:1-LPA+blood-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.195	0.00264	no	no	no	up	up	no	HC
DCA+stool	IL-13	DCA+stool-8-HETE+blood-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.195	0.00264	no	no	no	up	up	no	HC
DCA+stool	IL-13	DCA+stool-8-HETE+blood+AA+blood-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.195	0.00264	no	no	no	up	up	no	HC
DCA+stool	IL-13	DCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.195	0.00264	no	no	no	up	up	no	HC
DCA+stool	IL-13	DCA+stool-DL-methionine sulfoxide+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.195	0.00264	no	no	no	up	up	no	HC
2-hydroxyhippuric acid+urine	IL-13	2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13	Indirect	urine_cometabolism	serum_cytokines	0.215	0.00264	no	no	no	up	up	no	HC
Butyric acid+stool	IL-13	Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic-IL-13	Indirect	stool_scfa	serum_cytokines	0.102	0.00264	dn	no	no	up	up	no	HC
4-hydroxybenzoic acid+stool	IL-13	4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.00264	no	dn	no	up	up	no	HC
GCA+blood	IL-13	GCA+blood+TCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.16	0.00264	no	no	no	up	up	no	HC
GCA+blood	IL-13	GCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.16	0.00264	no	no	no	up	up	no	HC
GCA+blood	IL-13	GCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.16	0.00264	no	no	no	up	up	no	HC
GCA+blood	IL-13	GCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.16	0.00264	no	no	no	up	up	no	HC
ACA+stool	IL-13	ACA+stool+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.417	0.00264	no	no	no	up	up	no	HC
ACA+stool	IL-13	ACA+stool-Acetic acid+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.417	0.00264	no	no	no	up	up	no	HC
CDCA+blood	IL-13	CDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.506	0.00264	no	no	no	up	up	no	HC
capric acid C6+blood	IL-13	capric acid C6+blood-Cystine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.433	0.00264	no	no	no	up	up	no	HC
capric acid C6+blood	IL-13	capric acid C6+blood-Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.433	0.00264	no	no	no	up	up	no	HC
capric acid C6+blood	IL-13	capric acid C6+blood-Cystine+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.433	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-Lysosome+Phagosome-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-18:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-16:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-16:0/20:3-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-18:1/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-SFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-16:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-18:1/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella+18:0/18:1-PE+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-24:1+blood-d18:1-22:0-SM+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella+12-ketoDCA+blood-AA+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-16:1/16:0-PC+blood+AA+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-16:1/16:1-PC+blood+AA+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Human papillomavirus infection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Viral carcinogenesis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella+Estrogen signaling pathway-Viral carcinogenesis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-Lysosome+Viral carcinogenesis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella+18:1-LPE+blood+L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-18:1/18:1-PC+blood+20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella+18:1-LPE+blood-TXB2+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella+Estrogen signaling pathway-Autoimmune thyroid disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella+Estrogen signaling pathway-Allograft rejection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella+Estrogen signaling pathway-Graft-versus-host disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella+Estrogen signaling pathway-Type I diabetes mellitus-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella+Estrogen signaling pathway-Viral myocarditis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-16:0/16:0-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-Lysosome+Endocytosis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
Prevotella	IL-13	Prevotella-Lysosome+Natural killer cell mediated cytotoxicity-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.287	0.00264	no	no	no	up	up	no	HC
TCA+blood	IL-13	TCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.339	0.00264	no	no	no	up	up	no	HC
iso-DCA+blood	IL-13	iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.38	0.00264	no	no	no	up	up	no	HC
HCA+stool	IL-13	HCA+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.155	0.00264	no	no	no	up	up	no	HC
Roseburia	IL-13	Roseburia-L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.495	0.00264	no	no	no	up	up	no	HC
Roseburia	IL-13	Roseburia+TXB2+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.495	0.00264	no	no	no	up	up	no	HC
12-ketoDCA+stool	IL-13	12-ketoDCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.505	0.00264	no	no	no	up	up	no	HC
12-ketoDCA+stool	IL-13	12-ketoDCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.505	0.00264	no	no	no	up	up	no	HC
GLCA+blood	IL-13	GLCA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.319	0.00264	no	no	no	up	up	no	HC
L-Tryptophan+stool	IL-13	L-Tryptophan+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00264	no	no	no	up	up	no	HC
L-Tryptophan+stool	IL-13	L-Tryptophan+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00264	no	no	no	up	up	no	HC
L-Tryptophan+stool	IL-13	L-Tryptophan+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00264	no	no	no	up	up	no	HC
L-Tryptophan+stool	IL-13	L-Tryptophan+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00264	no	no	no	up	up	no	HC
L-Tryptophan+stool	IL-13	L-Tryptophan+stool-12-ketoDCA+blood-AA+blood-FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00264	no	no	no	up	up	no	HC
CA+blood	IL-13	CA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.606	0.00264	no	no	no	up	up	no	HC
GUDCA+stool	IL-13	GUDCA+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0085	0.00264	no	dn	no	up	up	no	HC
GUDCA+stool	IL-13	GUDCA+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0085	0.00264	no	dn	no	up	up	no	HC
L-Phenylalanine+stool	IL-13	L-Phenylalanine+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00264	no	no	no	up	up	no	HC
L-Phenylalanine+stool	IL-13	L-Phenylalanine+stool-12-ketoDCA+blood-AA+blood-FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00264	no	no	no	up	up	no	HC
L-Phenylalanine+stool	IL-13	L-Phenylalanine+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00264	no	no	no	up	up	no	HC
L-Phenylalanine+stool	IL-13	L-Phenylalanine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00264	no	no	no	up	up	no	HC
L-Phenylalanine+stool	IL-13	L-Phenylalanine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00264	no	no	no	up	up	no	HC
butyric acid C4+blood	IL-13	butyric acid C4+blood+Cystine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.407	0.00264	no	no	no	up	up	no	HC
butyric acid C4+blood	IL-13	butyric acid C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.407	0.00264	no	no	no	up	up	no	HC
butyric acid C4+blood	IL-13	butyric acid C4+blood+Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.407	0.00264	no	no	no	up	up	no	HC
butyric acid C4+blood	IL-13	butyric acid C4+blood+Cystine+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.407	0.00264	no	no	no	up	up	no	HC
GCA+stool	IL-13	GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	HC
GCA+stool	IL-13	GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	HC
GCA+stool	IL-13	GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	HC
GCA+stool	IL-13	GCA+stool+18:0/22:6-PE+blood-20:0+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	HC
GCA+stool	IL-13	GCA+stool+GDCA+stool-TXB2+blood-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	HC
GCA+stool	IL-13	GCA+stool-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus-18:1/18:2-PG+blood+AA+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus-Lysosome+Viral carcinogenesis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Ribosome biogenesis in eukaryotes-Viral carcinogenesis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus-Influenza A+Viral carcinogenesis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+TCA+stool-20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Primary immunodeficiency-20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Central carbon metabolism in cancer-20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Lachnospira-20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus-18:1-LPC+blood+20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus-Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus-18:2-LPC+blood+20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Primary immunodeficiency-Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Lachnospira-L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus-18:1-LPC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus-Lysosome+Endocytosis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Ribosome biogenesis in eukaryotes-Endocytosis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus-Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Ribosome biogenesis in eukaryotes-Allograft rejection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus-Influenza A+Allograft rejection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Ribosome biogenesis in eukaryotes-Cell adhesion molecules-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Ribosome biogenesis in eukaryotes-Autoimmune thyroid disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus-Influenza A+Autoimmune thyroid disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Ribosome biogenesis in eukaryotes-Cellular senescence-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus-Lysosome+Natural killer cell mediated cytotoxicity-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Ribosome biogenesis in eukaryotes-Natural killer cell mediated cytotoxicity-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Ribosome biogenesis in eukaryotes-Graft-versus-host disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus-Influenza A+Graft-versus-host disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Ribosome biogenesis in eukaryotes-Human papillomavirus infection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus-Influenza A+Human papillomavirus infection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Ribosome biogenesis in eukaryotes+mRNA surveillance pathway+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus-Lysosome+Phagosome-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Ribosome biogenesis in eukaryotes-Phagosome-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Ribosome biogenesis in eukaryotes+RNA degradation+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Ribosome biogenesis in eukaryotes-Type I diabetes mellitus-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus+Ribosome biogenesis in eukaryotes-Viral myocarditis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Coprococcus	IL-13	Coprococcus-Influenza A+Viral myocarditis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.612	0.00264	no	no	no	up	up	no	HC
Oscillospira	IL-13	Oscillospira-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.62	0.00264	no	no	no	up	up	no	HC
Oscillospira	IL-13	Oscillospira+L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.62	0.00264	no	no	no	up	up	no	HC
HCA+blood	IL-13	HCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.544	0.00264	no	no	no	up	up	no	HC
iso-LCA+stool	IL-13	iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	HC
iso-LCA+stool	IL-13	iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	HC
iso-LCA+stool	IL-13	iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	HC
iso-LCA+stool	IL-13	iso-LCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	HC
iso-LCA+stool	IL-13	iso-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	HC
iso-LCA+stool	IL-13	iso-LCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.72	0.00264	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-13	2-methyl-butyric acid m-C4+blood+20:1+blood-22:6n3+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.262	0.00264	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-13	2-methyl-butyric acid m-C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.262	0.00264	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-13	2-methyl-butyric acid m-C4+blood+decanoic acid C10+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.262	0.00264	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-13	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.262	0.00264	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-13	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.262	0.00264	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-13	2-methyl-butyric acid m-C4+blood-22:2-LPA+blood-d18:0-24:1-SM+blood+d18:1-22:0-SM+blood+FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.262	0.00264	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-13	2-methyl-butyric acid m-C4+blood+20:1+blood+20:1-LPC+blood-TXB2+blood-FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.262	0.00264	no	no	no	up	up	no	HC
DCA+blood	IL-13	DCA+blood+GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.122	0.00264	no	no	no	up	up	no	HC
DCA+blood	IL-13	DCA+blood+GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.122	0.00264	no	no	no	up	up	no	HC
DCA+blood	IL-13	DCA+blood+GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.122	0.00264	no	no	no	up	up	no	HC
DCA+blood	IL-13	DCA+blood+GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.122	0.00264	no	no	no	up	up	no	HC
DCA+blood	IL-13	DCA+blood+GUDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.122	0.00264	no	no	no	up	up	no	HC
DCA+blood	IL-13	DCA+blood+GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.122	0.00264	no	no	no	up	up	no	HC
DCA+blood	IL-13	"DCA+blood-n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13"	Indirect	serum_bileacids	serum_cytokines	0.122	0.00264	no	no	no	up	up	no	HC
DCA+blood	IL-13	DCA+blood+GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.122	0.00264	no	no	no	up	up	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-13	3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00264	no	no	no	up	up	no	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-13	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.00264	up	up	no	up	up	no	HC
GLCA+stool	IL-13	GLCA+stool-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.617	0.00264	no	no	no	up	up	no	HC
GLCA+stool	IL-13	GLCA+stool-iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.617	0.00264	no	no	no	up	up	no	HC
GLCA+stool	IL-13	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.617	0.00264	no	no	no	up	up	no	HC
GLCA+stool	IL-13	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.617	0.00264	no	no	no	up	up	no	HC
GLCA+stool	IL-13	GLCA+stool-iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.617	0.00264	no	no	no	up	up	no	HC
GLCA+stool	IL-13	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.617	0.00264	no	no	no	up	up	no	HC
GLCA+stool	IL-13	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.617	0.00264	no	no	no	up	up	no	HC
GLCA+stool	IL-13	GLCA+stool-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.617	0.00264	no	no	no	up	up	no	HC
GLCA+stool	IL-13	GLCA+stool-iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.617	0.00264	no	no	no	up	up	no	HC
GLCA+stool	IL-13	"GLCA+stool-LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+FGF basic-IL-13"	Indirect	stool_bileacids	serum_cytokines	0.617	0.00264	no	no	no	up	up	no	HC
GLCA+stool	IL-13	GLCA+stool-iso-LCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.617	0.00264	no	no	no	up	up	no	HC
GLCA+stool	IL-13	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.617	0.00264	no	no	no	up	up	no	HC
GLCA+stool	IL-13	GLCA+stool-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.617	0.00264	no	no	no	up	up	no	HC
GLCA+stool	IL-13	GLCA+stool-iso-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.617	0.00264	no	no	no	up	up	no	HC
GLCA+stool	IL-13	GLCA+stool-LCA+stool-TCA+stool-20:0+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.617	0.00264	no	no	no	up	up	no	HC
GLCA+stool	IL-13	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.617	0.00264	no	no	no	up	up	no	HC
GLCA+stool	IL-13	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.617	0.00264	no	no	no	up	up	no	HC
Indole-3-Acetic acid+stool	IL-13	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00264	no	no	no	up	up	no	HC
Indole-3-Acetic acid+stool	IL-13	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00264	no	no	no	up	up	no	HC
TCA+stool	IL-13	TCA+stool-20:0+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.458	0.00264	no	no	no	up	up	no	HC
HDCA+stool	IL-13	HDCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	HC
HDCA+stool	IL-13	HDCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	HC
HDCA+stool	IL-13	HDCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	HC
HDCA+stool	IL-13	HDCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	HC
HDCA+stool	IL-13	HDCA+stool+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	HC
HDCA+stool	IL-13	HDCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	HC
HDCA+stool	IL-13	HDCA+stool+16:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	HC
HDCA+stool	IL-13	HDCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	HC
HDCA+stool	IL-13	HDCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	HC
HDCA+stool	IL-13	HDCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	HC
HDCA+stool	IL-13	HDCA+stool+20:3/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.176	0.00264	no	no	no	up	up	no	HC
Lachnospira	IL-13	Lachnospira-L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.279	0.00264	no	no	no	up	up	no	HC
Lachnospira	IL-13	Lachnospira-20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.279	0.00264	no	no	no	up	up	no	HC
isobutyric acid C4+blood	IL-13	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.0151	0.00264	up	up	no	up	up	no	HC
isobutyric acid C4+blood	IL-13	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.0151	0.00264	up	up	no	up	up	no	HC
isobutyric acid C4+blood	IL-13	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.0151	0.00264	up	up	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool-9-HODE+blood-L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood+TXB2+blood-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood-TXB2+blood-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood-20:0+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool-Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool-9-HODE+blood+GPC+blood-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood+L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool+18:0/20:5-PC+blood-20:0-LPE+blood+d18:1-22:0-SM+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool+18:0/20:5-PC+blood+18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool+18:0/20:5-PC+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool+18:0/20:5-PC+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool+18:0/20:5-PC+blood+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool+18:0/20:5-PC+blood+18:1/18:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
GCDCA+stool	IL-13	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00264	no	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool+GCA+stool-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool+GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool+GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool+GCA+stool+GDCA+stool-TXB2+blood-FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-13	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-20:0+blood+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00264	dn	dn	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Endocrine resistance+Huntington disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Long-term depression+Huntington disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Pancreatic secretion+Huntington disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Aldosterone synthesis and secretion+Huntington disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Cushing syndrome+Huntington disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Endocrine resistance+L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Long-term depression+L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Pancreatic secretion+L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Aldosterone synthesis and secretion+L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter+Arginine and proline metabolism+Biosynthesis of amino acids-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Endocrine resistance+mRNA surveillance pathway+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Long-term depression-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Pancreatic secretion-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Long-term depression+Prion disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Pancreatic secretion+Prion disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Aldosterone synthesis and secretion+Prion disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Endocrine resistance+Non-alcoholic fatty liver disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Long-term depression+Non-alcoholic fatty liver disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Endocrine resistance+Parkinson disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Long-term depression+Parkinson disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter+Arginine and proline metabolism-Parkinson disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Pancreatic secretion+Parkinson disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Aldosterone synthesis and secretion+Parkinson disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Cushing syndrome+Parkinson disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Endocrine resistance+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Long-term depression+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter+Arginine and proline metabolism-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Pancreatic secretion+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Cushing syndrome+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Endocrine resistance+RNA degradation+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter+Arginine and proline metabolism-RNA degradation+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Endocrine resistance+Alzheimer disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Long-term depression+Alzheimer disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Pancreatic secretion+Alzheimer disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Aldosterone synthesis and secretion+Alzheimer disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Cushing syndrome+Alzheimer disease+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Phospholipase D signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Endocrine resistance+Thermogenesis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter+Arginine and proline metabolism-Thermogenesis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Endocrine resistance+Amyotrophic lateral sclerosis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Long-term depression+Amyotrophic lateral sclerosis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter+Arginine and proline metabolism-Amyotrophic lateral sclerosis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Pancreatic secretion+Amyotrophic lateral sclerosis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Cushing syndrome+Amyotrophic lateral sclerosis+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Pancreatic secretion+20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Morphine addiction+Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Long-term depression+Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Pancreatic secretion+Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Aldosterone synthesis and secretion+Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Odoribacter	IL-13	Odoribacter-Cushing syndrome+Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.798	0.00264	no	no	no	up	up	no	HC
Isobutyric acid+stool	IL-13	Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13	Indirect	stool_scfa	serum_cytokines	0.408	0.00264	no	no	no	up	up	no	HC
Isobutyric acid+stool	IL-13	Isobutyric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_scfa	serum_cytokines	0.408	0.00264	no	no	no	up	up	no	HC
Kynurenic acid+stool	IL-13	Kynurenic acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00264	dn	dn	no	up	up	no	HC
L-Tryptophan+urine	IL-13	L-Tryptophan+urine+FGF basic-IL-13	Indirect	urine_cometabolism	serum_cytokines	0.226	0.00264	no	no	no	up	up	no	HC
Eggerthella	IL-13	Eggerthella+Bacteroides-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.912	0.00264	no	no	no	up	up	no	HC
Anaerotruncus	IL-13	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	HC
Anaerotruncus	IL-13	Anaerotruncus-Gemmiger-Tuberculosis+Graft-versus-host disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	HC
Anaerotruncus	IL-13	Anaerotruncus-Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	HC
Anaerotruncus	IL-13	Anaerotruncus-Gemmiger-Tuberculosis-Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	HC
Anaerotruncus	IL-13	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Viral myocarditis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	HC
Anaerotruncus	IL-13	Anaerotruncus-Gemmiger-Tuberculosis+Viral myocarditis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	HC
Anaerotruncus	IL-13	Anaerotruncus-Gemmiger-GPC+blood-L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	HC
Anaerotruncus	IL-13	Anaerotruncus-Gemmiger-20:1-LPA+blood-L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	HC
Anaerotruncus	IL-13	Anaerotruncus-Gemmiger-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	HC
Anaerotruncus	IL-13	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Allograft rejection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	HC
Anaerotruncus	IL-13	Anaerotruncus-Gemmiger-Tuberculosis+Allograft rejection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	HC
Anaerotruncus	IL-13	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	HC
Anaerotruncus	IL-13	Anaerotruncus-Gemmiger-Tuberculosis+Autoimmune thyroid disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	HC
Anaerotruncus	IL-13	Anaerotruncus-Gemmiger+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	HC
Anaerotruncus	IL-13	Anaerotruncus-Gemmiger-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.904	0.00264	no	no	no	up	up	no	HC
Anaerostipes	IL-13	Anaerostipes-20:0+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.568	0.00264	no	no	no	up	up	no	HC
Isovaleric acid+stool	IL-13	Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_scfa	serum_cytokines	0.343	0.00264	no	no	no	up	up	no	HC
Isovaleric acid+stool	IL-13	Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13	Indirect	stool_scfa	serum_cytokines	0.343	0.00264	no	no	no	up	up	no	HC
Isovaleric acid+stool	IL-13	Isovaleric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_scfa	serum_cytokines	0.343	0.00264	no	no	no	up	up	no	HC
Paraprevotella	IL-13	Paraprevotella-L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	HC
Paraprevotella	IL-13	Paraprevotella+AA+blood-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.118	0.00264	no	no	no	up	up	no	HC
Homovanillic acid+urine	IL-13	Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13	Indirect	urine_cometabolism	serum_cytokines	0.45	0.00264	no	no	no	up	up	no	HC
Homovanillic acid+urine	IL-13	Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	urine_cometabolism	serum_cytokines	0.45	0.00264	no	no	no	up	up	no	HC
TDCA+blood	IL-13	TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.155	0.00264	no	up	no	up	up	no	HC
iso-LCA+blood	IL-13	iso-LCA+blood-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.507	0.00264	no	no	no	up	up	no	HC
iso-LCA+blood	IL-13	iso-LCA+blood-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.507	0.00264	no	no	no	up	up	no	HC
iso-LCA+blood	IL-13	iso-LCA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.507	0.00264	no	no	no	up	up	no	HC
¦Ø-MCA+stool	IL-13	¦Ø-MCA+stool-Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.919	0.00264	no	no	no	up	up	no	HC
¦Ø-MCA+stool	IL-13	¦Ø-MCA+stool-Acetic acid+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.919	0.00264	no	no	no	up	up	no	HC
Phenylacetic acid+stool	IL-13	Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.785	0.00264	no	no	no	up	up	no	HC
Phenylacetic acid+stool	IL-13	Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.785	0.00264	no	no	no	up	up	no	HC
Gemmiger	IL-13	Gemmiger-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	HC
Gemmiger	IL-13	Gemmiger-Tuberculosis+Graft-versus-host disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	HC
Gemmiger	IL-13	Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	HC
Gemmiger	IL-13	Gemmiger-Tuberculosis-Diabetic cardiomyopathy+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	HC
Gemmiger	IL-13	Gemmiger-Staphylococcus aureus infection+Viral myocarditis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	HC
Gemmiger	IL-13	Gemmiger-Tuberculosis+Viral myocarditis-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	HC
Gemmiger	IL-13	Gemmiger-GPC+blood-L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	HC
Gemmiger	IL-13	Gemmiger-20:1-LPA+blood-L-Homocystine+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	HC
Gemmiger	IL-13	Gemmiger-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	HC
Gemmiger	IL-13	Gemmiger-Staphylococcus aureus infection+Allograft rejection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	HC
Gemmiger	IL-13	Gemmiger-Tuberculosis+Allograft rejection-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	HC
Gemmiger	IL-13	Gemmiger-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	HC
Gemmiger	IL-13	Gemmiger-Tuberculosis+Autoimmune thyroid disease-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	HC
Gemmiger	IL-13	Gemmiger+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	HC
Gemmiger	IL-13	Gemmiger-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.595	0.00264	no	no	no	up	up	no	HC
GDCA+stool	IL-13	GDCA+stool-TXB2+blood-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.656	0.00264	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-13	L-Tyrosine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00264	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-13	L-Tyrosine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00264	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-13	L-Tyrosine+stool+PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00264	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-13	L-Tyrosine+stool+20:1-LPA+blood-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00264	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-13	L-Tyrosine+stool+8-HETE+blood-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00264	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-13	L-Tyrosine+stool-12-ketoDCA+blood-AA+blood-FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00264	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-13	L-Tyrosine+stool+8-HETE+blood+AA+blood-FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00264	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-13	L-Tyrosine+stool+8-HETE+blood+TXB2+blood-FGF basic-IL-13	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00264	no	no	no	up	up	no	HC
CDCA+stool	IL-13	CDCA+stool+18:3n3+blood+AA+blood-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.663	0.00264	no	no	no	up	up	no	HC
CDCA+stool	IL-13	CDCA+stool+TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.663	0.00264	no	no	no	up	up	no	HC
CDCA+stool	IL-13	CDCA+stool+nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.663	0.00264	no	no	no	up	up	no	HC
CDCA+stool	IL-13	CDCA+stool+HCA+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.663	0.00264	no	no	no	up	up	no	HC
CDCA+stool	IL-13	CDCA+stool+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.663	0.00264	no	no	no	up	up	no	HC
CDCA+stool	IL-13	CDCA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.663	0.00264	no	no	no	up	up	no	HC
CDCA+stool	IL-13	CDCA+stool-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.663	0.00264	no	no	no	up	up	no	HC
CA+stool	IL-13	CA+stool+nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.827	0.00264	no	no	no	up	up	no	HC
CA+stool	IL-13	CA+stool+HCA+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.827	0.00264	no	no	no	up	up	no	HC
CA+stool	IL-13	CA+stool-ACA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.827	0.00264	no	no	no	up	up	no	HC
CA+stool	IL-13	CA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.827	0.00264	no	no	no	up	up	no	HC
CA+stool	IL-13	CA+stool+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.827	0.00264	no	no	no	up	up	no	HC
CA+stool	IL-13	CA+stool-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.827	0.00264	no	no	no	up	up	no	HC
CA+stool	IL-13	CA+stool+GDCA+stool-TXB2+blood-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.827	0.00264	no	no	no	up	up	no	HC
CA+stool	IL-13	CA+stool+TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.827	0.00264	no	no	no	up	up	no	HC
CA+stool	IL-13	CA+stool-18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.827	0.00264	no	no	no	up	up	no	HC
HDCA+blood	IL-13	HDCA+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.483	0.00264	no	no	no	up	up	no	HC
HDCA+blood	IL-13	HDCA+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.483	0.00264	no	no	no	up	up	no	HC
HDCA+blood	IL-13	HDCA+blood+SFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.483	0.00264	no	no	no	up	up	no	HC
HDCA+blood	IL-13	HDCA+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.483	0.00264	no	no	no	up	up	no	HC
UDCA+stool	IL-13	UDCA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.266	0.00264	no	no	no	up	up	no	HC
UDCA+stool	IL-13	UDCA+stool+18:3n3+blood+AA+blood-FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.266	0.00264	no	no	no	up	up	no	HC
LCA+blood	IL-13	LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.884	0.00264	no	no	no	up	up	no	HC
nutriCA+stool	IL-13	nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13	Indirect	stool_bileacids	serum_cytokines	0.481	0.00264	no	no	no	up	up	no	HC
GDCA+blood	IL-13	GDCA+blood+TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.632	0.00264	no	no	no	up	up	no	HC
P-hydroxyhippuric acid+urine	IL-13	P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	urine_cometabolism	serum_cytokines	0.436	0.00264	no	no	no	up	up	no	HC
acetic acid C2+blood	IL-13	acetic acid C2+blood-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.000193	0.00264	up	dn	no	up	up	no	HC
isovaleric acid iso-C5+blood	IL-13	isovaleric acid iso-C5+blood+Sarcosine+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13	Indirect	serum_scfa	serum_cytokines	0.117	0.00264	no	no	no	up	up	no	HC
L-Phenylalanine+urine	IL-13	L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13	Indirect	urine_cometabolism	serum_cytokines	0.0908	0.00264	no	up	no	up	up	no	HC
Clostridium	IL-13	Clostridium+P-hydroxyhippuric acid+urine-FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	HC
Clostridium	IL-13	Clostridium-L-Tryptophan+urine+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.925	0.00264	no	no	no	up	up	no	HC
12-ketoDCA+blood	IL-13	12-ketoDCA+blood-AA+blood-FGF basic-IL-13	Indirect	serum_bileacids	serum_cytokines	0.517	0.00264	no	no	no	up	up	no	HC
Butyricicoccus	IL-13	Butyricicoccus+d18:1-22:0-SM+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.852	0.00264	no	no	no	up	up	no	HC
3-Hydroxy-L-kynurenine+urine	IL-13	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine+FGF basic-IL-13	Indirect	urine_cometabolism	serum_cytokines	0.401	0.00264	no	no	no	up	up	no	HC
Wautersiella	IL-13	Wautersiella+Butyricicoccus+d18:1-22:0-SM+blood+FGF basic-IL-13	Indirect	Genus	serum_cytokines	0.289	0.00264	no	no	no	up	up	no	HC
Blautia	IL-4	Blautia+Arginine and proline metabolism-Various types of N-glycan biosynthesis+T cell receptor signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Ras signaling pathway+Signaling pathways regulating pluripotency of stem cells+T cell receptor signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Arginine and proline metabolism+RIG-I-like receptor signaling pathway+T cell receptor signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Arginine and proline metabolism-Various types of N-glycan biosynthesis+Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Ras signaling pathway+Neurotrophin signaling pathway+Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Ras signaling pathway+Long-term potentiation+Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Ras signaling pathway+Sphingolipid signaling pathway+Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Ras signaling pathway+Signaling pathways regulating pluripotency of stem cells+Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Peroxisome-Hippo signaling pathway-Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Ras signaling pathway+Circadian rhythm+Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Ras signaling pathway+VEGF signaling pathway+Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Arginine and proline metabolism+cGMP-PKG signaling pathway+Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Arginine and proline metabolism+RIG-I-like receptor signaling pathway+Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+16:0/20:5-PC+blood-18:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Peroxisome+Primary immunodeficiency-L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Chemical carcinogenesis - receptor activation+18:0-LPC+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Cushing syndrome+18:0-LPC+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Ras signaling pathway+Oocyte meiosis-L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Peroxisome+Central carbon metabolism in cancer-L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-18:2-LPC+blood-d18:1-14:1-SM+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-18:1-LPE+blood-24:1+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Peroxisome+Longevity regulating pathway - multiple species-L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Peroxisome-Kaposi sarcoma-associated herpesvirus infection+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Cushing syndrome+Kaposi sarcoma-associated herpesvirus infection+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+16:0/20:5-PC+blood-18:0/18:2-PI+blood-Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Peroxisome+Primary immunodeficiency-Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Peroxisome+AGE-RAGE signaling pathway in diabetic complications+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Chemical carcinogenesis - receptor activation-Graft-versus-host disease+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Chemical carcinogenesis - receptor activation+18:0-LPC+blood-Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Cushing syndrome+18:0-LPC+blood-Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Chemical carcinogenesis - receptor activation-Viral myocarditis+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Chemical carcinogenesis - receptor activation-Autoimmune thyroid disease+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Ras signaling pathway+Oocyte meiosis-Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Chemical carcinogenesis - receptor activation-Allograft rejection+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Chemical carcinogenesis - receptor activation-Rheumatoid arthritis+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Cushing syndrome-Rheumatoid arthritis+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Butyric acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-18:1-LPE+blood-24:1+blood+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Arginine and proline metabolism+Lysosome+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Peroxisome+Primary immunodeficiency-L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-18:2-LPC+blood+HDCA+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-18:2-LPC+blood-d18:1-14:1-SM+blood-L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Peroxisome+Longevity regulating pathway - multiple species-L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Arginine and proline metabolism+Apoptosis+L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Peroxisome+Primary immunodeficiency-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Peroxisome+Central carbon metabolism in cancer-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-18:2-LPC+blood-d18:1-14:1-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-18:2-LPC+blood-d18:1-14:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-ACA+blood-d18:1-14:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Cushing syndrome-Leishmaniasis-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Peroxisome-Mineral absorption+L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Cushing syndrome+Mineral absorption+L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-18:2-LPC+blood-d18:1-14:1-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Ras signaling pathway-GCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Peroxisome+18:0/18:0-PS+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Ras signaling pathway-GCDCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	"Blautia+Peroxisome-Circadian entrainment-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	"Blautia-18:2-LPC+blood-d18:1-14:0-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	"Blautia-ACA+blood-d18:1-14:0-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	"Blautia-Cushing syndrome+Salivary secretion-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	"Blautia-Ras signaling pathway+Gastric cancer+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	"Blautia+Arginine and proline metabolism-Gastric cancer+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Ras signaling pathway+Oocyte meiosis-L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Ras signaling pathway+TGF-beta signaling pathway-L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Peroxisome-TGF-beta signaling pathway-L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Arginine and proline metabolism-TGF-beta signaling pathway-L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Ras signaling pathway+Axon guidance-L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-18:2-LPC+blood-d18:1-14:1-SM+blood-L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Ras signaling pathway+Axon guidance-Hematopoietic cell lineage+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Arginine and proline metabolism+Fatty acid metabolism+Hematopoietic cell lineage+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Arginine and proline metabolism+Histidine metabolism+Hematopoietic cell lineage+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+Peroxisome+AGE-RAGE signaling pathway in diabetic complications+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia+16:0/20:5-PC+blood-Choline+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Butyric acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-18:1-LPE+blood-L-Histidine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-18:2-LPC+blood-d18:1-14:1-SM+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-CA+blood-L-Isoleucine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-18:1-LPE+blood-L-Isoleucine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-Cushing syndrome-Leishmaniasis-L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Blautia	IL-4	Blautia-18:1-LPE+blood-Cysteine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	1.36E-05	0.858	up	dn	dn	no	no	no	HC
Parabacteroides	IL-4	Parabacteroides+18:0/22:6-PA+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	4.19E-05	0.858	no	up	up	no	no	no	HC
Parabacteroides	IL-4	Parabacteroides-9-HODE+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	4.19E-05	0.858	no	up	up	no	no	no	HC
Parabacteroides	IL-4	Parabacteroides+Ethanolamine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	4.19E-05	0.858	no	up	up	no	no	no	HC
Parabacteroides	IL-4	Parabacteroides-9-HODE+blood-L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	4.19E-05	0.858	no	up	up	no	no	no	HC
Parabacteroides	IL-4	Parabacteroides+Ethanolamine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	4.19E-05	0.858	no	up	up	no	no	no	HC
Parabacteroides	IL-4	Parabacteroides+Carbon metabolism-Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	4.19E-05	0.858	no	up	up	no	no	no	HC
Parabacteroides	IL-4	Parabacteroides+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	4.19E-05	0.858	no	up	up	no	no	no	HC
Parabacteroides	IL-4	Parabacteroides+Ethanolamine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	4.19E-05	0.858	no	up	up	no	no	no	HC
Dorea	IL-4	Dorea-VEGF signaling pathway+Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.00362	0.858	up	no	dn	no	no	no	HC
Dorea	IL-4	Dorea+Legionellosis-L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.00362	0.858	up	no	dn	no	no	no	HC
Dorea	IL-4	Dorea-Fc epsilon RI signaling pathway+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.00362	0.858	up	no	dn	no	no	no	HC
Dorea	IL-4	Dorea+Legionellosis-Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.00362	0.858	up	no	dn	no	no	no	HC
Dorea	IL-4	Dorea-18:0-LPC+blood-Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.00362	0.858	up	no	dn	no	no	no	HC
Dorea	IL-4	Dorea-18:0-LPC+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.00362	0.858	up	no	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium-Staphylococcus aureus infection+Influenza A+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium-Staphylococcus aureus infection+Autoimmune thyroid disease+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium+4-hydroxybenzoic acid+stool+18:0/18:2-PI+blood-Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium-Staphylococcus aureus infection+Viral myocarditis+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium-Staphylococcus aureus infection+Asthma+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium+Butyric acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium-Staphylococcus aureus infection+Allograft rejection+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium-Staphylococcus aureus infection+Rheumatoid arthritis+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium-Staphylococcus aureus infection+Graft-versus-host disease+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium-Staphylococcus aureus infection+Influenza A+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium+Butyric acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium+4-hydroxybenzoic acid+stool+Cysteine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium-Staphylococcus aureus infection+Influenza A+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium-Staphylococcus aureus infection-Kaposi sarcoma-associated herpesvirus infection+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium+4-hydroxybenzoic acid+stool+18:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium-Staphylococcus aureus infection+Asthma+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium-Staphylococcus aureus infection+Influenza A+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-4	Faecalibacterium-Staphylococcus aureus infection+Influenza A+L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0039	0.858	no	dn	dn	no	no	no	HC
isocapric acid iso-C6+blood	IL-4	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.0458	0.858	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	IL-4	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.0458	0.858	no	no	dn	no	no	no	HC
Bacteroides	IL-4	"Bacteroides+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	0.000267	0.858	dn	dn	up	no	no	no	HC
Propionic acid+stool	IL-4	Propionic acid+stool+16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.0436	0.858	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-4	Propionic acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.0436	0.858	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-4	Propionic acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.0436	0.858	dn	no	up	no	no	no	HC
[Ruminococcus]	IL-4	[Ruminococcus]+9-HODE+blood-L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0679	0.858	no	no	dn	no	no	no	HC
[Ruminococcus]	IL-4	[Ruminococcus]+9-HODE+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0679	0.858	no	no	dn	no	no	no	HC
GUDCA+blood	IL-4	GUDCA+blood-iso-DCA+blood+L-Histidine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.0766	0.858	no	no	dn	no	no	no	HC
Acetic acid+stool	IL-4	Acetic acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.0656	0.858	dn	no	no	no	no	no	HC
Acetic acid+stool	IL-4	Acetic acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.0656	0.858	dn	no	no	no	no	no	HC
Acetic acid+stool	IL-4	Acetic acid+stool+16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.0656	0.858	dn	no	no	no	no	no	HC
Alistipes	IL-4	Alistipes+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0114	0.858	no	up	no	no	no	no	HC
Alistipes	IL-4	Alistipes-Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.0114	0.858	no	up	no	no	no	no	HC
Butyricimonas	IL-4	Butyricimonas-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.17	0.858	no	no	no	no	no	no	HC
Collinsella	IL-4	Collinsella+18:0/18:0-PS+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	HC
Collinsella	IL-4	"Collinsella+Glycine, serine and threonine metabolism-Cholinergic synapse-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	HC
Collinsella	IL-4	"Collinsella+Glycine, serine and threonine metabolism-L-Lysine+blood+Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	0.128	0.858	no	no	no	no	no	no	HC
iso-DCA+stool	IL-4	iso-DCA+stool-L-Tryptophan+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.155	0.858	no	no	no	no	no	no	HC
iso-DCA+stool	IL-4	iso-DCA+stool-L-Tryptophan+stool+18:1/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.155	0.858	no	no	no	no	no	no	HC
iso-DCA+stool	IL-4	iso-DCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.155	0.858	no	no	no	no	no	no	HC
iso-DCA+stool	IL-4	iso-DCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.155	0.858	no	no	no	no	no	no	HC
iso-DCA+stool	IL-4	iso-DCA+stool-L-Tryptophan+stool+L-2-Aminobutyric acid+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.155	0.858	no	no	no	no	no	no	HC
iso-DCA+stool	IL-4	iso-DCA+stool-L-Tryptophan+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.155	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	"LCA+stool+16:0/18:1-PC+blood-20:3n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	"LCA+stool+18:0/16:0-PC+blood-20:3n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	"LCA+stool+18:0/16:0-PC+blood-TCA+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:1/16:0-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood-16:0/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood-18:1/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:1/16:0-PC+blood-18:1/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:1/16:0-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood-18:0-LPE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:1/16:0-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood+18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood+18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood+18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:1/16:0-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood-18:1/18:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:1/16:0-PC+blood-18:1/18:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood+Creatinine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood+Creatinine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool-TCA+stool-Creatinine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:1/16:0-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood-16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood-18:0-LPE+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:1/16:0-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood+Creatinine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood+Creatinine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool-TCA+stool-Creatinine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood+Glycine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood+Glycine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:1/16:0-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:2-LPA+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool-DMG+blood+L-Arginine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool-DMG+blood+L-Citrulline+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:1/16:0-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood+16:0/20:4-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood+16:0/20:4-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool-TCA+stool+16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood+18:0/22:6-PA+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood+18:0/22:6-PA+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood+18:1/18:0-PS+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood+18:1/18:0-PS+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood+d18:1-20:1-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:2-LPA+blood-DL-methionine sulfoxide+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:1/16:0-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:2-LPA+blood-DL-methionine sulfoxide+blood+L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool-DMG+blood+L-Citrulline+blood+L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:1/16:0-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool-TCA+stool+18:3n6+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:1/16:0-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood+Creatinine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood+Creatinine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool-TCA+stool-Creatinine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool-DMG+blood+L-Arginine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:1/16:0-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool-TCA+stool-Choline+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood+L-Histidine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:1/16:0-PC+blood+L-Histidine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood+Creatinine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood+Creatinine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool-TCA+stool-Creatinine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:2-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+16:0/18:1-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:1/16:0-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
LCA+stool	IL-4	LCA+stool+18:0/16:0-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.314	0.858	no	no	no	no	no	no	HC
Akkermansia	IL-4	Akkermansia-GLCA+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.23	0.858	no	no	no	no	no	no	HC
Bifidobacterium	IL-4	Bifidobacterium-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.105	0.858	no	dn	no	no	no	no	HC
Ruminococcus	IL-4	Ruminococcus-Lysosome+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	HC
Ruminococcus	IL-4	Ruminococcus-Endocytosis+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	HC
Ruminococcus	IL-4	Ruminococcus-FoxO signaling pathway+T cell receptor signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	HC
Ruminococcus	IL-4	Ruminococcus-cGMP-PKG signaling pathway+Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	HC
Ruminococcus	IL-4	Ruminococcus-FoxO signaling pathway+Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.335	0.858	no	no	no	no	no	no	HC
GCDCA+blood	IL-4	GCDCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.31	0.858	no	no	no	no	no	no	HC
[Prevotella]	IL-4	[Prevotella]+Ethanolamine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.367	0.858	no	no	no	no	no	no	HC
[Prevotella]	IL-4	[Prevotella]+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.367	0.858	no	no	no	no	no	no	HC
[Prevotella]	IL-4	[Prevotella]+Ethanolamine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.367	0.858	no	no	no	no	no	no	HC
[Prevotella]	IL-4	[Prevotella]+GLCA+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.367	0.858	no	no	no	no	no	no	HC
[Prevotella]	IL-4	[Prevotella]+Ethanolamine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.367	0.858	no	no	no	no	no	no	HC
ACA+blood	IL-4	ACA+blood-d18:1-14:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.338	0.858	no	no	no	no	no	no	HC
ACA+blood	IL-4	"ACA+blood-d18:1-14:0-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	serum_bileacids	serum_cytokines	0.338	0.858	no	no	no	no	no	no	HC
DCA+stool	IL-4	DCA+stool-DL-methionine sulfoxide+blood+L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.195	0.858	no	no	no	no	no	no	HC
DCA+stool	IL-4	DCA+stool-DL-methionine sulfoxide+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.195	0.858	no	no	no	no	no	no	HC
Butyric acid+stool	IL-4	Butyric acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.102	0.858	dn	no	no	no	no	no	HC
Butyric acid+stool	IL-4	Butyric acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.102	0.858	dn	no	no	no	no	no	HC
4-hydroxybenzoic acid+stool	IL-4	4-hydroxybenzoic acid+stool+Cysteine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.858	no	dn	no	no	no	no	HC
4-hydroxybenzoic acid+stool	IL-4	4-hydroxybenzoic acid+stool+18:0/18:2-PI+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.858	no	dn	no	no	no	no	HC
4-hydroxybenzoic acid+stool	IL-4	4-hydroxybenzoic acid+stool+18:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.858	no	dn	no	no	no	no	HC
GCA+blood	IL-4	GCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.16	0.858	no	no	no	no	no	no	HC
ACA+stool	IL-4	ACA+stool-18:0/18:2-PI+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.417	0.858	no	no	no	no	no	no	HC
ACA+stool	IL-4	ACA+stool-18:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.417	0.858	no	no	no	no	no	no	HC
CDCA+blood	IL-4	CDCA+blood-Creatinine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.506	0.858	no	no	no	no	no	no	HC
CDCA+blood	IL-4	CDCA+blood+GCDCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.506	0.858	no	no	no	no	no	no	HC
CDCA+blood	IL-4	CDCA+blood-Creatinine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.506	0.858	no	no	no	no	no	no	HC
CDCA+blood	IL-4	CDCA+blood-Creatinine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.506	0.858	no	no	no	no	no	no	HC
CDCA+blood	IL-4	CDCA+blood-L-2-Aminobutyric acid+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.506	0.858	no	no	no	no	no	no	HC
CDCA+blood	IL-4	CDCA+blood-Creatinine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.506	0.858	no	no	no	no	no	no	HC
capric acid C6+blood	IL-4	capric acid C6+blood-Cystine+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.433	0.858	no	no	no	no	no	no	HC
Prevotella	IL-4	Prevotella-24:1+blood+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	HC
Prevotella	IL-4	Prevotella+Estrogen signaling pathway-Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	HC
Prevotella	IL-4	Prevotella-Lysosome+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	HC
Prevotella	IL-4	Prevotella-24:1+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	HC
Prevotella	IL-4	Prevotella+Estrogen signaling pathway-L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	HC
Prevotella	IL-4	"Prevotella-18:1/20:3-PC+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	HC
Prevotella	IL-4	Prevotella+Estrogen signaling pathway-L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.287	0.858	no	no	no	no	no	no	HC
TCA+blood	IL-4	"TCA+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	serum_bileacids	serum_cytokines	0.339	0.858	no	no	no	no	no	no	HC
iso-DCA+blood	IL-4	iso-DCA+blood+L-Histidine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.38	0.858	no	no	no	no	no	no	HC
HCA+stool	IL-4	HCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.155	0.858	no	no	no	no	no	no	HC
HCA+stool	IL-4	HCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.155	0.858	no	no	no	no	no	no	HC
Roseburia	IL-4	Roseburia-T cell receptor signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.495	0.858	no	no	no	no	no	no	HC
12-ketoDCA+stool	IL-4	12-ketoDCA+stool-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.505	0.858	no	no	no	no	no	no	HC
GLCA+blood	IL-4	GLCA+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.319	0.858	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-4	L-Tryptophan+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.557	0.858	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-4	L-Tryptophan+stool+18:1/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.557	0.858	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-4	L-Tryptophan+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.557	0.858	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-4	L-Tryptophan+stool+L-2-Aminobutyric acid+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.557	0.858	no	no	no	no	no	no	HC
CA+blood	IL-4	CA+blood-L-Isoleucine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.606	0.858	no	no	no	no	no	no	HC
GUDCA+stool	IL-4	GUDCA+stool+Phenylacetic acid+stool+d18:1-20:1-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0085	0.858	no	dn	no	no	no	no	HC
GUDCA+stool	IL-4	GUDCA+stool+L-Tryptophan+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0085	0.858	no	dn	no	no	no	no	HC
GUDCA+stool	IL-4	GUDCA+stool+L-Tryptophan+stool+L-2-Aminobutyric acid+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0085	0.858	no	dn	no	no	no	no	HC
GUDCA+stool	IL-4	GUDCA+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0085	0.858	no	dn	no	no	no	no	HC
GUDCA+stool	IL-4	GUDCA+stool+L-Tryptophan+stool+18:1/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0085	0.858	no	dn	no	no	no	no	HC
GUDCA+stool	IL-4	GUDCA+stool+L-Tryptophan+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0085	0.858	no	dn	no	no	no	no	HC
GUDCA+stool	IL-4	GUDCA+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0085	0.858	no	dn	no	no	no	no	HC
GUDCA+stool	IL-4	GUDCA+stool+Phenylacetic acid+stool-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0085	0.858	no	dn	no	no	no	no	HC
GUDCA+stool	IL-4	GUDCA+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0085	0.858	no	dn	no	no	no	no	HC
GUDCA+stool	IL-4	GUDCA+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0085	0.858	no	dn	no	no	no	no	HC
GUDCA+stool	IL-4	GUDCA+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0085	0.858	no	dn	no	no	no	no	HC
L-Phenylalanine+stool	IL-4	L-Phenylalanine+stool-18:3n6+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.398	0.858	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IL-4	L-Phenylalanine+stool+18:1/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.398	0.858	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-4	butyric acid C4+blood+Cystine+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.407	0.858	no	no	no	no	no	no	HC
GCA+stool	IL-4	GCA+stool+16:0/18:0-PS+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	HC
GCA+stool	IL-4	GCA+stool+18:0/22:6-PE+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	HC
GCA+stool	IL-4	GCA+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	HC
GCA+stool	IL-4	GCA+stool+16:0/18:0-PS+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	HC
GCA+stool	IL-4	GCA+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0809	0.858	no	no	no	no	no	no	HC
Coprococcus	IL-4	Coprococcus-Influenza A+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	HC
Coprococcus	IL-4	Coprococcus-Choline+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	HC
Coprococcus	IL-4	Coprococcus-Influenza A+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	HC
Coprococcus	IL-4	Coprococcus+Primary immunodeficiency-L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	HC
Coprococcus	IL-4	Coprococcus+Central carbon metabolism in cancer-L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	HC
Coprococcus	IL-4	Coprococcus+16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	HC
Coprococcus	IL-4	Coprococcus-Influenza A+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	HC
Coprococcus	IL-4	Coprococcus+Primary immunodeficiency-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	HC
Coprococcus	IL-4	Coprococcus+Central carbon metabolism in cancer-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	HC
Coprococcus	IL-4	Coprococcus+3-(3-Hydroxyphenyl)propanoic acid+stool-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	HC
Coprococcus	IL-4	Coprococcus+Ribosome biogenesis in eukaryotes-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	HC
Coprococcus	IL-4	Coprococcus+Primary immunodeficiency-L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	HC
Coprococcus	IL-4	Coprococcus-Influenza A+L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	HC
Coprococcus	IL-4	Coprococcus+Primary immunodeficiency-Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	HC
Coprococcus	IL-4	Coprococcus-Lysosome+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	HC
Coprococcus	IL-4	Coprococcus+Ribosome biogenesis in eukaryotes-Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	HC
Coprococcus	IL-4	Coprococcus-Influenza A+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.612	0.858	no	no	no	no	no	no	HC
Oscillospira	IL-4	Oscillospira-9-HODE+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.62	0.858	no	no	no	no	no	no	HC
Oscillospira	IL-4	Oscillospira-9-HODE+blood-L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.62	0.858	no	no	no	no	no	no	HC
HCA+blood	IL-4	HCA+blood-L-2-Aminobutyric acid+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.544	0.858	no	no	no	no	no	no	HC
HCA+blood	IL-4	HCA+blood-L-Isoleucine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.544	0.858	no	no	no	no	no	no	HC
iso-LCA+stool	IL-4	iso-LCA+stool-16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.72	0.858	no	no	no	no	no	no	HC
iso-LCA+stool	IL-4	iso-LCA+stool-16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.72	0.858	no	no	no	no	no	no	HC
iso-LCA+stool	IL-4	iso-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.72	0.858	no	no	no	no	no	no	HC
iso-LCA+stool	IL-4	iso-LCA+stool-16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.72	0.858	no	no	no	no	no	no	HC
iso-LCA+stool	IL-4	iso-LCA+stool-16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.72	0.858	no	no	no	no	no	no	HC
iso-LCA+stool	IL-4	iso-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.72	0.858	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-4	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.262	0.858	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-4	2-methyl-butyric acid m-C4+blood+butyric acid C4+blood+Cystine+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.262	0.858	no	no	no	no	no	no	HC
DCA+blood	IL-4	"DCA+blood-n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	serum_bileacids	serum_cytokines	0.122	0.858	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-4	3-(3-Hydroxyphenyl)propanoic acid+stool-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.33	0.858	no	no	no	no	no	no	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-4	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.858	up	up	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:2-LPA+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool-TCA+stool+16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Creatinine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Creatinine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool-TCA+stool-Creatinine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Glycine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Glycine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+16:0/20:4-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+16:0/20:4-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool-DMG+blood+L-Citrulline+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool-DMG+blood+L-Arginine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:0-LPE+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-iso-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool-DMG+blood+L-Citrulline+blood+L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:2-LPA+blood-DL-methionine sulfoxide+blood+L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Creatinine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Creatinine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool-TCA+stool-Creatinine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+L-Histidine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Histidine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool-DMG+blood+L-Arginine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool-TCA+stool+18:3n6+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool-TCA+stool-Choline+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Creatinine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Creatinine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool-TCA+stool-Creatinine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-16:0/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-18:1/18:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:1/18:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-18:1/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:1/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:0-LPE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+18:0/22:6-PA+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+18:0/22:6-PA+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+18:1/18:0-PS+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+18:1/18:0-PS+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-iso-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+d18:1-20:1-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:2-LPA+blood-DL-methionine sulfoxide+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Creatinine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Creatinine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool-TCA+stool-Creatinine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	"GLCA+stool-LCA+stool+18:0/16:0-PC+blood-TCA+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	"GLCA+stool-LCA+stool+16:0/18:1-PC+blood-20:3n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
GLCA+stool	IL-4	"GLCA+stool-LCA+stool+18:0/16:0-PC+blood-20:3n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	stool_bileacids	serum_cytokines	0.617	0.858	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-4	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-18:3n6+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.304	0.858	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-4	Indole-3-Acetic acid+stool+L-Tryptophan+stool+L-2-Aminobutyric acid+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.304	0.858	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-4	Indole-3-Acetic acid+stool+L-Tryptophan+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.304	0.858	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-4	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+d18:1-20:1-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.304	0.858	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-4	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.304	0.858	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-4	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.304	0.858	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-4	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+18:1/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.304	0.858	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-4	Indole-3-Acetic acid+stool+L-Tryptophan+stool+18:1/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.304	0.858	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-4	Indole-3-Acetic acid+stool+L-Tryptophan+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.304	0.858	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-4	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.304	0.858	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-4	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.304	0.858	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-4	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.304	0.858	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-4	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.304	0.858	no	no	no	no	no	no	HC
TCA+stool	IL-4	TCA+stool-Creatinine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.458	0.858	no	no	no	no	no	no	HC
TCA+stool	IL-4	TCA+stool+18:3n6+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.458	0.858	no	no	no	no	no	no	HC
TCA+stool	IL-4	TCA+stool-Creatinine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.458	0.858	no	no	no	no	no	no	HC
TCA+stool	IL-4	TCA+stool-Choline+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.458	0.858	no	no	no	no	no	no	HC
TCA+stool	IL-4	TCA+stool-Creatinine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.458	0.858	no	no	no	no	no	no	HC
TCA+stool	IL-4	TCA+stool+16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.458	0.858	no	no	no	no	no	no	HC
TCA+stool	IL-4	TCA+stool-Creatinine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.458	0.858	no	no	no	no	no	no	HC
HDCA+stool	IL-4	HDCA+stool+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	HC
HDCA+stool	IL-4	HDCA+stool+Ethanolamine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	HC
HDCA+stool	IL-4	HDCA+stool+Ethanolamine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	HC
HDCA+stool	IL-4	HDCA+stool+16:0/20:4-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	HC
HDCA+stool	IL-4	HDCA+stool+Ethanolamine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	HC
HDCA+stool	IL-4	HDCA+stool+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.176	0.858	no	no	no	no	no	no	HC
Lachnospira	IL-4	Lachnospira+18:0/22:6-PE+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.279	0.858	no	no	no	no	no	no	HC
isobutyric acid C4+blood	IL-4	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.0151	0.858	up	up	no	no	no	no	HC
GCDCA+stool	IL-4	GCDCA+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0471	0.858	no	dn	no	no	no	no	HC
GCDCA+stool	IL-4	GCDCA+stool-9-HODE+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0471	0.858	no	dn	no	no	no	no	HC
GCDCA+stool	IL-4	GCDCA+stool-9-HODE+blood-L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0471	0.858	no	dn	no	no	no	no	HC
GCDCA+stool	IL-4	GCDCA+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.0471	0.858	no	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+GCA+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+GCDCA+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-Propionic acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+GCA+stool+16:0/18:0-PS+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+GCA+stool+16:0/18:0-PS+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+GCA+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+GCDCA+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool-Propionic acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+GCDCA+stool-9-HODE+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-4	5-Hydroxytryptamine+stool+GCDCA+stool-9-HODE+blood-L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.858	dn	dn	no	no	no	no	HC
Odoribacter	IL-4	Odoribacter-18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.798	0.858	no	no	no	no	no	no	HC
Odoribacter	IL-4	Odoribacter-Phospholipase D signaling pathway+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.798	0.858	no	no	no	no	no	no	HC
Odoribacter	IL-4	Odoribacter-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.798	0.858	no	no	no	no	no	no	HC
Odoribacter	IL-4	Odoribacter-Phospholipase D signaling pathway+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.798	0.858	no	no	no	no	no	no	HC
Odoribacter	IL-4	Odoribacter-Phospholipase D signaling pathway+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.798	0.858	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-4	Isobutyric acid+stool+Phenylacetic acid+stool+d18:1-20:1-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.408	0.858	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-4	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.408	0.858	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-4	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.408	0.858	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-4	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.408	0.858	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-4	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.408	0.858	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-4	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.408	0.858	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-4	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.408	0.858	no	no	no	no	no	no	HC
Kynurenic acid+stool	IL-4	Kynurenic acid+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.037	0.858	dn	dn	no	no	no	no	HC
Kynurenic acid+stool	IL-4	Kynurenic acid+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.037	0.858	dn	dn	no	no	no	no	HC
Eggerthella	IL-4	"Eggerthella+Bacteroides+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	0.912	0.858	no	no	no	no	no	no	HC
Anaerotruncus	IL-4	Anaerotruncus-Gemmiger+GLCA+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.904	0.858	no	no	no	no	no	no	HC
Anaerotruncus	IL-4	Anaerotruncus-Gemmiger-Cysteine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.904	0.858	no	no	no	no	no	no	HC
Anaerostipes	IL-4	Anaerostipes-Th1 and Th2 cell differentiation+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.568	0.858	no	no	no	no	no	no	HC
Anaerostipes	IL-4	Anaerostipes-Th17 cell differentiation+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.568	0.858	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-4	Isovaleric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.343	0.858	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-4	Isovaleric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.343	0.858	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-4	Isovaleric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.343	0.858	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-4	Isovaleric acid+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.343	0.858	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-4	Isovaleric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.343	0.858	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-4	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.343	0.858	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-4	Isovaleric acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.343	0.858	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-4	Isovaleric acid+stool-nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.343	0.858	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-4	Isovaleric acid+stool+Phenylacetic acid+stool+d18:1-20:1-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_scfa	serum_cytokines	0.343	0.858	no	no	no	no	no	no	HC
Paraprevotella	IL-4	Paraprevotella+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	HC
Paraprevotella	IL-4	Paraprevotella+Rheumatoid arthritis+Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	HC
Paraprevotella	IL-4	Paraprevotella+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	HC
Paraprevotella	IL-4	Paraprevotella+Carbon metabolism-Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	HC
Paraprevotella	IL-4	Paraprevotella-Autophagy - animal+Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	HC
Paraprevotella	IL-4	Paraprevotella-p53 signaling pathway+Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	HC
Paraprevotella	IL-4	Paraprevotella-C-type lectin receptor signaling pathway+Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	HC
Paraprevotella	IL-4	Paraprevotella-Autophagy - animal+T cell receptor signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	HC
Paraprevotella	IL-4	Paraprevotella-C-type lectin receptor signaling pathway+T cell receptor signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.118	0.858	no	no	no	no	no	no	HC
iso-LCA+blood	IL-4	"iso-LCA+blood+L-Proline+blood-MUFA+blood+n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	serum_bileacids	serum_cytokines	0.507	0.858	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IL-4	¦Ø-MCA+stool-Propionic acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.919	0.858	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IL-4	¦Ø-MCA+stool-Acetic acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.919	0.858	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IL-4	¦Ø-MCA+stool-Butyric acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.919	0.858	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IL-4	¦Ø-MCA+stool-Propionic acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.919	0.858	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IL-4	¦Ø-MCA+stool-Acetic acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.919	0.858	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IL-4	¦Ø-MCA+stool-Butyric acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.919	0.858	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IL-4	¦Ø-MCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.919	0.858	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IL-4	¦Ø-MCA+stool-Acetic acid+stool+16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.919	0.858	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-4	Phenylacetic acid+stool-14:0/18:2-PC+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.785	0.858	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-4	Phenylacetic acid+stool+d18:1-20:1-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.785	0.858	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-4	Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.785	0.858	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-4	Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.785	0.858	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-4	Phenylacetic acid+stool-16:0/20:4-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.785	0.858	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-4	Phenylacetic acid+stool-16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.785	0.858	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-4	Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.785	0.858	no	no	no	no	no	no	HC
Gemmiger	IL-4	Gemmiger+GLCA+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	HC
Gemmiger	IL-4	Gemmiger-Cysteine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.595	0.858	no	no	no	no	no	no	HC
GDCA+stool	IL-4	GDCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.656	0.858	no	no	no	no	no	no	HC
GDCA+stool	IL-4	GDCA+stool-L-Isoleucine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.656	0.858	no	no	no	no	no	no	HC
GDCA+stool	IL-4	GDCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.656	0.858	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-4	L-Tyrosine+stool+18:1/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.44	0.858	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-4	L-Tyrosine+stool-18:3n6+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_cometabolism	serum_cytokines	0.44	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+HCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+18:3n3+blood-GCDCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+18:3n3+blood+DHA+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+18:3n3+blood-GCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool-DCA+stool-DL-methionine sulfoxide+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool-HDCA+stool+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+GCA+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool-HDCA+stool+Ethanolamine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+GCA+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+18:3n3+blood+butyric acid C4+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+GCA+stool+16:0/18:0-PS+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	"CDCA+stool+18:3n3+blood+n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+HCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+18:3n3+blood+DHA+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool-DCA+stool-DL-methionine sulfoxide+blood+L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool-HDCA+stool+Ethanolamine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+18:3n3+blood+DHA+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+GCA+stool+16:0/18:0-PS+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool+GCA+stool+18:0/22:6-PE+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool-HDCA+stool+16:0/20:4-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool-HDCA+stool+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CDCA+stool	IL-4	CDCA+stool-HDCA+stool+Ethanolamine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.663	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool+GCA+stool+16:0/18:0-PS+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-18:1/16:0-PC+blood-20:2/18:1-PE+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool+GCA+stool+18:0/22:6-PE+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-HDCA+stool+16:0/20:4-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-HDCA+stool+Ethanolamine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-18:1/16:0-PC+blood+Ethanolamine+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-HDCA+stool+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-18:1/16:0-PC+blood+20:3/16:0-PC+blood+L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool+GCA+stool+16:0/18:0-PS+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-18:1/16:0-PC+blood-20:2/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-18:1/16:0-PC+blood-18:1/18:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-18:1/16:0-PC+blood-18:1/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-18:1/16:0-PC+blood-18:1/16:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-18:1/16:0-PC+blood-18:1/18:1-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-18:1/16:0-PC+blood-18:3/16:0-PE+blood-Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-Propionic acid+stool-18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool+GCA+stool+18:0/20:5-PC+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-18:1/16:0-PC+blood-18:3n6+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-18:1/16:0-PC+blood-18:3/16:0-PE+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool+GDCA+stool-L-Isoleucine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-Propionic acid+stool-18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool+GCA+stool+18:0/20:5-PC+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-18:1/16:0-PC+blood+L-Histidine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-HDCA+stool+Ethanolamine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-18:1/16:0-PC+blood+Ethanolamine+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool+nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool+GDCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool+HCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-18:1/16:0-PC+blood-GCDCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-DCA+stool-DL-methionine sulfoxide+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-ACA+blood-d18:1-14:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool+nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool+GDCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool+HCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-DCA+stool-DL-methionine sulfoxide+blood+L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool+16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-HDCA+stool+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-18:1/16:0-PC+blood+Ethanolamine+blood+L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool+16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-HDCA+stool+Ethanolamine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	CA+stool-18:1/16:0-PC+blood+Ethanolamine+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
CA+stool	IL-4	"CA+stool-ACA+blood-d18:1-14:0-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	stool_bileacids	serum_cytokines	0.827	0.858	no	no	no	no	no	no	HC
HDCA+blood	IL-4	HDCA+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.483	0.858	no	no	no	no	no	no	HC
UDCA+stool	IL-4	"UDCA+stool+18:3n3+blood+n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	stool_bileacids	serum_cytokines	0.266	0.858	no	no	no	no	no	no	HC
UDCA+stool	IL-4	UDCA+stool+16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Glutamic acid+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.266	0.858	no	no	no	no	no	no	HC
UDCA+stool	IL-4	UDCA+stool+18:3n3+blood+butyric acid C4+blood+Cystine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.266	0.858	no	no	no	no	no	no	HC
UDCA+stool	IL-4	UDCA+stool+18:3n3+blood+DHA+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.266	0.858	no	no	no	no	no	no	HC
UDCA+stool	IL-4	UDCA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.266	0.858	no	no	no	no	no	no	HC
UDCA+stool	IL-4	UDCA+stool+16:0/18:3-PC+blood+18:3/18:2-PC+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.266	0.858	no	no	no	no	no	no	HC
UDCA+stool	IL-4	UDCA+stool+18:3n3+blood+DHA+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.266	0.858	no	no	no	no	no	no	HC
UDCA+stool	IL-4	UDCA+stool+18:3n3+blood+DHA+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.266	0.858	no	no	no	no	no	no	HC
UDCA+stool	IL-4	UDCA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.266	0.858	no	no	no	no	no	no	HC
UDCA+stool	IL-4	UDCA+stool+18:3n3+blood-GCDCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.266	0.858	no	no	no	no	no	no	HC
UDCA+stool	IL-4	UDCA+stool+18:3n3+blood-GCA+blood+L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.266	0.858	no	no	no	no	no	no	HC
nutriCA+stool	IL-4	nutriCA+stool+d18:1-20:0-SM+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.481	0.858	no	no	no	no	no	no	HC
nutriCA+stool	IL-4	nutriCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	stool_bileacids	serum_cytokines	0.481	0.858	no	no	no	no	no	no	HC
acetic acid C2+blood	IL-4	acetic acid C2+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.000193	0.858	up	dn	no	no	no	no	HC
acetic acid C2+blood	IL-4	acetic acid C2+blood+heptanoic acid C7+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	serum_scfa	serum_cytokines	0.000193	0.858	up	dn	no	no	no	no	HC
Clostridium	IL-4	Clostridium-Toll-like receptor signaling pathway+Cholinergic synapse-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	Clostridium+18:0/20:3-PC+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	Clostridium+14:0/18:2-PC+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	Clostridium+20:2/18:0-PC+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	Clostridium+d18:1-14:0-SM+blood-L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	Clostridium-Adipocytokine signaling pathway+L-Ornithine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	Clostridium+14:0/18:2-PC+blood-Cystine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	Clostridium+14:0/18:2-PC+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	Clostridium-Adipocytokine signaling pathway+L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	Clostridium+DPA+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	"Clostridium+TCA+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	"Clostridium+d18:1-14:0-SM+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	Clostridium-Toll-like receptor signaling pathway+T cell receptor signaling pathway-Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	Clostridium+18:0/20:3-PC+blood-L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	Clostridium+14:0/18:2-PC+blood-L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	Clostridium+20:2/18:0-PC+blood-L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	Clostridium+18:0/20:3-PC+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	Clostridium+20:2/18:0-PC+blood-L-Alanine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
Clostridium	IL-4	Clostridium-Adipocytokine signaling pathway+L-Alanine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.925	0.858	no	no	no	no	no	no	HC
12-ketoDCA+blood	IL-4	12-ketoDCA+blood+16:0/16:1-PI+blood-L-Lysine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	HC
12-ketoDCA+blood	IL-4	12-ketoDCA+blood-DPA+blood-L-Glutamine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	HC
12-ketoDCA+blood	IL-4	12-ketoDCA+blood+14:0/16:0-PC+blood-L-Asparagine+blood+Eotaxin+IL-4	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	HC
12-ketoDCA+blood	IL-4	"12-ketoDCA+blood-n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	serum_bileacids	serum_cytokines	0.517	0.858	no	no	no	no	no	no	HC
Butyricicoccus	IL-4	Butyricicoccus-HDCA+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.852	0.858	no	no	no	no	no	no	HC
Butyricicoccus	IL-4	"Butyricicoccus-Salivary secretion-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	0.852	0.858	no	no	no	no	no	no	HC
Wautersiella	IL-4	Wautersiella+Butyricicoccus-HDCA+blood+L-Asparagine+blood+Eotaxin+IL-4	Indirect	Genus	serum_cytokines	0.289	0.858	no	no	no	no	no	no	HC
Wautersiella	IL-4	"Wautersiella+Butyricicoccus-Salivary secretion-3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin+IL-4"	Indirect	Genus	serum_cytokines	0.289	0.858	no	no	no	no	no	no	HC
Blautia	IL-2	Blautia+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	1.36E-05	0.522	up	dn	dn	no	no	no	HC
Parabacteroides	IL-2	Parabacteroides+Biosynthesis of amino acids-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	4.19E-05	0.522	no	up	up	no	no	no	HC
Parabacteroides	IL-2	Parabacteroides-RNA degradation+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	4.19E-05	0.522	no	up	up	no	no	no	HC
Parabacteroides	IL-2	Parabacteroides-mRNA surveillance pathway+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	4.19E-05	0.522	no	up	up	no	no	no	HC
Dorea	IL-2	Dorea-VEGF signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Fc epsilon RI signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-18:2-LPC+blood+20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Endocrine resistance+Huntington disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Endocrine resistance+L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Chemical carcinogenesis - receptor activation+L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	"Dorea-Growth hormone synthesis, secretion and action+L-Homocystine+blood+FGF basic-IL-13-IL-2"	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Endocrine resistance+mRNA surveillance pathway+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Endocrine resistance+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-GnRH signaling pathway+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Endocrine resistance+Parkinson disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-GnRH signaling pathway+Parkinson disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Endocrine resistance+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Endocrine resistance+RNA degradation+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Endocrine resistance+Thermogenesis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Thyroid hormone signaling pathway+Viral myocarditis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Chemical carcinogenesis - receptor activation-Viral myocarditis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-16:0-LPC+blood+AA+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Amphetamine addiction-Human papillomavirus infection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Amphetamine addiction-Autoimmune thyroid disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Chemical carcinogenesis - receptor activation-Autoimmune thyroid disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-16:0-LPC+blood+TXB2+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Amphetamine addiction-Allograft rejection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Chemical carcinogenesis - receptor activation-Allograft rejection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Amphetamine addiction-Graft-versus-host disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Chemical carcinogenesis - receptor activation-Graft-versus-host disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea+Legionellosis-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Amphetamine addiction+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Chemical carcinogenesis - receptor activation+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Amphetamine addiction-Viral carcinogenesis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Endocrine resistance+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-GnRH signaling pathway+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Chemical carcinogenesis - receptor activation-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Dorea	IL-2	Dorea-Endocrine resistance+Alzheimer disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.00362	0.522	up	no	dn	no	no	no	HC
Faecalibacterium	IL-2	Faecalibacterium+Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0039	0.522	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-2	Faecalibacterium-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0039	0.522	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-2	Faecalibacterium-Staphylococcus aureus infection+Viral myocarditis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0039	0.522	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-2	Faecalibacterium-Staphylococcus aureus infection+Allograft rejection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0039	0.522	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-2	Faecalibacterium-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0039	0.522	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-2	Faecalibacterium+4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0039	0.522	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-2	Faecalibacterium-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0039	0.522	no	dn	dn	no	no	no	HC
TUDCA+blood	IL-2	TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.0282	0.522	no	no	dn	no	no	no	HC
TUDCA+blood	IL-2	TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.0282	0.522	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	IL-2	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.0458	0.522	no	no	dn	no	no	no	HC
Bacteroides	IL-2	Bacteroides-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.000267	0.522	dn	dn	up	no	no	no	HC
Propionic acid+stool	IL-2	Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_scfa	serum_cytokines	0.0436	0.522	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-2	Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_scfa	serum_cytokines	0.0436	0.522	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-2	Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_scfa	serum_cytokines	0.0436	0.522	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-2	Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_scfa	serum_cytokines	0.0436	0.522	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-2	Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_scfa	serum_cytokines	0.0436	0.522	dn	no	up	no	no	no	HC
[Ruminococcus]	IL-2	[Ruminococcus]+nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	HC
[Ruminococcus]	IL-2	[Ruminococcus]+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	HC
[Ruminococcus]	IL-2	[Ruminococcus]-Hypotaurine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0679	0.522	no	no	dn	no	no	no	HC
GUDCA+blood	IL-2	GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.0766	0.522	no	no	dn	no	no	no	HC
GUDCA+blood	IL-2	GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.0766	0.522	no	no	dn	no	no	no	HC
GUDCA+blood	IL-2	GUDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.0766	0.522	no	no	dn	no	no	no	HC
GUDCA+blood	IL-2	GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.0766	0.522	no	no	dn	no	no	no	HC
GUDCA+blood	IL-2	GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.0766	0.522	no	no	dn	no	no	no	HC
GUDCA+blood	IL-2	GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.0766	0.522	no	no	dn	no	no	no	HC
GUDCA+blood	IL-2	GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.0766	0.522	no	no	dn	no	no	no	HC
Acetic acid+stool	IL-2	Acetic acid+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_scfa	serum_cytokines	0.0656	0.522	dn	no	no	no	no	no	HC
Alistipes	IL-2	Alistipes+SFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes+20:3/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes+16:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-GDCA+stool-TXB2+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-MAPK signaling pathway-Cell adhesion molecules-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Lipid and atherosclerosis+AA+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Progesterone-mediated oocyte maturation-Allograft rejection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-MAPK signaling pathway-Allograft rejection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Peroxisome-Cardiac muscle contraction+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Peroxisome-Alzheimer disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Progesterone-mediated oocyte maturation-Autoimmune thyroid disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-MAPK signaling pathway-Autoimmune thyroid disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Peroxisome-Prion disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Peroxisome-Huntington disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Progesterone-mediated oocyte maturation-Viral myocarditis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Autophagy - animal-Viral myocarditis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-MAPK signaling pathway-Viral myocarditis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Cholinergic synapse-Viral myocarditis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Peroxisome+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Peroxisome-Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Peroxisome-Thermogenesis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-NOD-like receptor signaling pathway-Thermogenesis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Autophagy - animal+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-GABAergic synapse+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-FoxO signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Peroxisome+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Autophagy - animal+L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-GABAergic synapse-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-FoxO signaling pathway-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Peroxisome-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-NOD-like receptor signaling pathway-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Olfactory transduction-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Primary immunodeficiency-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Peroxisome-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Primary immunodeficiency-20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-16:0/18:2-PI+blood-20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Central carbon metabolism in cancer-20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Peroxisome-20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Olfactory transduction-20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Progesterone-mediated oocyte maturation-Type I diabetes mellitus-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-MAPK signaling pathway-Type I diabetes mellitus-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-GABAergic synapse-Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Peroxisome-Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-NOD-like receptor signaling pathway-Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Progesterone-mediated oocyte maturation-Graft-versus-host disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-MAPK signaling pathway-Graft-versus-host disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-GABAergic synapse-Parkinson disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-Peroxisome-Parkinson disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Alistipes	IL-2	Alistipes-NOD-like receptor signaling pathway-Parkinson disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.0114	0.522	no	up	no	no	no	no	HC
Butyricimonas	IL-2	Butyricimonas+Prion disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.17	0.522	no	no	no	no	no	no	HC
Butyricimonas	IL-2	Butyricimonas+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.17	0.522	no	no	no	no	no	no	HC
Butyricimonas	IL-2	Butyricimonas+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.17	0.522	no	no	no	no	no	no	HC
Collinsella	IL-2	Collinsella-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.128	0.522	no	no	no	no	no	no	HC
iso-DCA+stool	IL-2	iso-DCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.155	0.522	no	no	no	no	no	no	HC
LCA+stool	IL-2	"LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2"	Indirect	stool_bileacids	serum_cytokines	0.314	0.522	no	no	no	no	no	no	HC
LCA+stool	IL-2	LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.314	0.522	no	no	no	no	no	no	HC
LCA+stool	IL-2	LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.314	0.522	no	no	no	no	no	no	HC
LCA+stool	IL-2	LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.314	0.522	no	no	no	no	no	no	HC
LCA+stool	IL-2	LCA+stool-TCA+stool-20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.314	0.522	no	no	no	no	no	no	HC
LCA+stool	IL-2	LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.314	0.522	no	no	no	no	no	no	HC
LCA+stool	IL-2	LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.314	0.522	no	no	no	no	no	no	HC
LCA+stool	IL-2	LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.314	0.522	no	no	no	no	no	no	HC
LCA+stool	IL-2	LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.314	0.522	no	no	no	no	no	no	HC
LCA+stool	IL-2	LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.314	0.522	no	no	no	no	no	no	HC
LCA+stool	IL-2	LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.314	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia+Systemic lupus erythematosus+Graft-versus-host disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Ribosome-Phagosome-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Ribosome+Cardiac muscle contraction+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Wnt signaling pathway+Retrograde endocannabinoid signaling+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Wnt signaling pathway+Prion disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Ribosome+Prion disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Ribosome-Endocytosis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Wnt signaling pathway+Thermogenesis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Ribosome+Thermogenesis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Wnt signaling pathway+Alzheimer disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Ribosome+Alzheimer disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Ribosome+mRNA surveillance pathway+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Wnt signaling pathway+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Ribosome+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia+Pertussis+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia+Systemic lupus erythematosus+Allograft rejection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Ribosome+RNA degradation+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Acetic acid+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Wnt signaling pathway-Cell adhesion molecules-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Ribosome-Cell adhesion molecules-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Wnt signaling pathway-Human papillomavirus infection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia+Pertussis+Human papillomavirus infection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Ribosome-Human papillomavirus infection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Wnt signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Ribosome+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Wnt signaling pathway-Natural killer cell mediated cytotoxicity-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Ribosome-Natural killer cell mediated cytotoxicity-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Wnt signaling pathway+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Ribosome+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Wnt signaling pathway+Huntington disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Ribosome+Huntington disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Wnt signaling pathway+Parkinson disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Ribosome+Parkinson disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Wnt signaling pathway+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Coronavirus disease - COVID-19+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia-Ribosome+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Akkermansia	IL-2	Akkermansia+Systemic lupus erythematosus-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.23	0.522	no	no	no	no	no	no	HC
Bifidobacterium	IL-2	Bifidobacterium+TXB2+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	HC
Bifidobacterium	IL-2	Bifidobacterium+AA+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.105	0.522	no	dn	no	no	no	no	HC
Ruminococcus	IL-2	Ruminococcus+Thermogenesis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.335	0.522	no	no	no	no	no	no	HC
Ruminococcus	IL-2	Ruminococcus-Endocytosis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.335	0.522	no	no	no	no	no	no	HC
Ruminococcus	IL-2	Ruminococcus-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.335	0.522	no	no	no	no	no	no	HC
Ruminococcus	IL-2	Ruminococcus-Biosynthesis of amino acids-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.335	0.522	no	no	no	no	no	no	HC
Ruminococcus	IL-2	Ruminococcus+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.335	0.522	no	no	no	no	no	no	HC
GCDCA+blood	IL-2	GCDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.31	0.522	no	no	no	no	no	no	HC
GCDCA+blood	IL-2	GCDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.31	0.522	no	no	no	no	no	no	HC
GCDCA+blood	IL-2	GCDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.31	0.522	no	no	no	no	no	no	HC
GCDCA+blood	IL-2	GCDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.31	0.522	no	no	no	no	no	no	HC
GCDCA+blood	IL-2	GCDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.31	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]-18:0/22:6-PC+blood-20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]-Glutamatergic synapse-d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]+24:0+blood+AA+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]-Aldosterone synthesis and secretion+Alzheimer disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]-18:0/22:6-PC+blood+TXB2+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]-GnRH signaling pathway+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]-Aldosterone synthesis and secretion+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]-Morphine addiction+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	"[Prevotella]-Growth hormone synthesis, secretion and action+L-Homocystine+blood+FGF basic-IL-13-IL-2"	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]-Aldosterone synthesis and secretion+L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]+24:0+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]-Aldosterone synthesis and secretion+Huntington disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]-Aldosterone synthesis and secretion+Parkinson disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]-GnRH signaling pathway+Parkinson disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]-GnRH signaling pathway+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]-Aldosterone synthesis and secretion+Prion disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
[Prevotella]	IL-2	[Prevotella]+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.367	0.522	no	no	no	no	no	no	HC
ACA+blood	IL-2	ACA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.338	0.522	no	no	no	no	no	no	HC
DCA+stool	IL-2	DCA+stool-8-HETE+blood+TXB2+blood-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.195	0.522	no	no	no	no	no	no	HC
DCA+stool	IL-2	DCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.195	0.522	no	no	no	no	no	no	HC
DCA+stool	IL-2	DCA+stool-20:1-LPA+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.195	0.522	no	no	no	no	no	no	HC
DCA+stool	IL-2	DCA+stool-8-HETE+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.195	0.522	no	no	no	no	no	no	HC
DCA+stool	IL-2	DCA+stool-8-HETE+blood+AA+blood-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.195	0.522	no	no	no	no	no	no	HC
DCA+stool	IL-2	DCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.195	0.522	no	no	no	no	no	no	HC
DCA+stool	IL-2	DCA+stool-DL-methionine sulfoxide+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.195	0.522	no	no	no	no	no	no	HC
2-hydroxyhippuric acid+urine	IL-2	2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	urine_cometabolism	serum_cytokines	0.215	0.522	no	no	no	no	no	no	HC
Butyric acid+stool	IL-2	Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2	Indirect	stool_scfa	serum_cytokines	0.102	0.522	dn	no	no	no	no	no	HC
4-hydroxybenzoic acid+stool	IL-2	4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.522	no	dn	no	no	no	no	HC
GCA+blood	IL-2	GCA+blood+TCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.16	0.522	no	no	no	no	no	no	HC
GCA+blood	IL-2	GCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.16	0.522	no	no	no	no	no	no	HC
GCA+blood	IL-2	GCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.16	0.522	no	no	no	no	no	no	HC
GCA+blood	IL-2	GCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.16	0.522	no	no	no	no	no	no	HC
ACA+stool	IL-2	ACA+stool+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.417	0.522	no	no	no	no	no	no	HC
ACA+stool	IL-2	ACA+stool-Acetic acid+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.417	0.522	no	no	no	no	no	no	HC
CDCA+blood	IL-2	CDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.506	0.522	no	no	no	no	no	no	HC
capric acid C6+blood	IL-2	capric acid C6+blood-Cystine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.433	0.522	no	no	no	no	no	no	HC
capric acid C6+blood	IL-2	capric acid C6+blood-Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.433	0.522	no	no	no	no	no	no	HC
capric acid C6+blood	IL-2	capric acid C6+blood-Cystine+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.433	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-Lysosome+Phagosome-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-18:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-16:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-16:0/20:3-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-18:1/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-SFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-16:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-18:1/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella+18:0/18:1-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-24:1+blood-d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella+12-ketoDCA+blood-AA+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-16:1/16:0-PC+blood+AA+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-16:1/16:1-PC+blood+AA+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Human papillomavirus infection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Viral carcinogenesis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella+Estrogen signaling pathway-Viral carcinogenesis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-Lysosome+Viral carcinogenesis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella+18:1-LPE+blood+L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-18:1/18:1-PC+blood+20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella+18:1-LPE+blood-TXB2+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella+Estrogen signaling pathway-Autoimmune thyroid disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella+Estrogen signaling pathway-Allograft rejection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella+Estrogen signaling pathway-Graft-versus-host disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella+Estrogen signaling pathway-Type I diabetes mellitus-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella+Estrogen signaling pathway-Viral myocarditis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-16:0/16:0-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-Lysosome+Endocytosis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
Prevotella	IL-2	Prevotella-Lysosome+Natural killer cell mediated cytotoxicity-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.287	0.522	no	no	no	no	no	no	HC
TCA+blood	IL-2	TCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.339	0.522	no	no	no	no	no	no	HC
iso-DCA+blood	IL-2	iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.38	0.522	no	no	no	no	no	no	HC
HCA+stool	IL-2	HCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.155	0.522	no	no	no	no	no	no	HC
Roseburia	IL-2	Roseburia-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.495	0.522	no	no	no	no	no	no	HC
Roseburia	IL-2	Roseburia+TXB2+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.495	0.522	no	no	no	no	no	no	HC
12-ketoDCA+stool	IL-2	12-ketoDCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.505	0.522	no	no	no	no	no	no	HC
12-ketoDCA+stool	IL-2	12-ketoDCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.505	0.522	no	no	no	no	no	no	HC
GLCA+blood	IL-2	GLCA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.319	0.522	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-2	L-Tryptophan+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.557	0.522	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-2	L-Tryptophan+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.557	0.522	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-2	L-Tryptophan+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.557	0.522	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-2	L-Tryptophan+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.557	0.522	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-2	L-Tryptophan+stool-12-ketoDCA+blood-AA+blood-FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.557	0.522	no	no	no	no	no	no	HC
CA+blood	IL-2	CA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.606	0.522	no	no	no	no	no	no	HC
GUDCA+stool	IL-2	GUDCA+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0085	0.522	no	dn	no	no	no	no	HC
GUDCA+stool	IL-2	GUDCA+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0085	0.522	no	dn	no	no	no	no	HC
L-Phenylalanine+stool	IL-2	L-Phenylalanine+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.398	0.522	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IL-2	L-Phenylalanine+stool-12-ketoDCA+blood-AA+blood-FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.398	0.522	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IL-2	L-Phenylalanine+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.398	0.522	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IL-2	L-Phenylalanine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.398	0.522	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IL-2	L-Phenylalanine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.398	0.522	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-2	butyric acid C4+blood+Cystine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.407	0.522	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-2	butyric acid C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.407	0.522	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-2	butyric acid C4+blood+Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.407	0.522	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-2	butyric acid C4+blood+Cystine+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.407	0.522	no	no	no	no	no	no	HC
GCA+stool	IL-2	GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0809	0.522	no	no	no	no	no	no	HC
GCA+stool	IL-2	GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0809	0.522	no	no	no	no	no	no	HC
GCA+stool	IL-2	GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0809	0.522	no	no	no	no	no	no	HC
GCA+stool	IL-2	GCA+stool+18:0/22:6-PE+blood-20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0809	0.522	no	no	no	no	no	no	HC
GCA+stool	IL-2	GCA+stool+GDCA+stool-TXB2+blood-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0809	0.522	no	no	no	no	no	no	HC
GCA+stool	IL-2	GCA+stool-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0809	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus-18:1/18:2-PG+blood+AA+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus-Lysosome+Viral carcinogenesis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Ribosome biogenesis in eukaryotes-Viral carcinogenesis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus-Influenza A+Viral carcinogenesis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+TCA+stool-20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Primary immunodeficiency-20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Central carbon metabolism in cancer-20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Lachnospira-20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus-18:1-LPC+blood+20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus-Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus-18:2-LPC+blood+20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Primary immunodeficiency-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Lachnospira-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus-18:1-LPC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus-Lysosome+Endocytosis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Ribosome biogenesis in eukaryotes-Endocytosis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus-Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Ribosome biogenesis in eukaryotes-Allograft rejection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus-Influenza A+Allograft rejection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Ribosome biogenesis in eukaryotes-Cell adhesion molecules-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Ribosome biogenesis in eukaryotes-Autoimmune thyroid disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus-Influenza A+Autoimmune thyroid disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Ribosome biogenesis in eukaryotes-Cellular senescence-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus-Lysosome+Natural killer cell mediated cytotoxicity-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Ribosome biogenesis in eukaryotes-Natural killer cell mediated cytotoxicity-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Ribosome biogenesis in eukaryotes-Graft-versus-host disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus-Influenza A+Graft-versus-host disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Ribosome biogenesis in eukaryotes-Human papillomavirus infection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus-Influenza A+Human papillomavirus infection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Ribosome biogenesis in eukaryotes+mRNA surveillance pathway+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus-Lysosome+Phagosome-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Ribosome biogenesis in eukaryotes-Phagosome-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Ribosome biogenesis in eukaryotes+RNA degradation+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Ribosome biogenesis in eukaryotes-Type I diabetes mellitus-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus+Ribosome biogenesis in eukaryotes-Viral myocarditis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Coprococcus	IL-2	Coprococcus-Influenza A+Viral myocarditis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.612	0.522	no	no	no	no	no	no	HC
Oscillospira	IL-2	Oscillospira-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	HC
Oscillospira	IL-2	Oscillospira+L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.62	0.522	no	no	no	no	no	no	HC
HCA+blood	IL-2	HCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.544	0.522	no	no	no	no	no	no	HC
iso-LCA+stool	IL-2	iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.72	0.522	no	no	no	no	no	no	HC
iso-LCA+stool	IL-2	iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.72	0.522	no	no	no	no	no	no	HC
iso-LCA+stool	IL-2	iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.72	0.522	no	no	no	no	no	no	HC
iso-LCA+stool	IL-2	iso-LCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.72	0.522	no	no	no	no	no	no	HC
iso-LCA+stool	IL-2	iso-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.72	0.522	no	no	no	no	no	no	HC
iso-LCA+stool	IL-2	iso-LCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.72	0.522	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-2	2-methyl-butyric acid m-C4+blood+20:1+blood-22:6n3+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.262	0.522	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-2	2-methyl-butyric acid m-C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.262	0.522	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-2	2-methyl-butyric acid m-C4+blood+decanoic acid C10+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.262	0.522	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-2	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.262	0.522	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-2	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.262	0.522	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-2	2-methyl-butyric acid m-C4+blood-22:2-LPA+blood-d18:0-24:1-SM+blood+d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.262	0.522	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-2	2-methyl-butyric acid m-C4+blood+20:1+blood+20:1-LPC+blood-TXB2+blood-FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.262	0.522	no	no	no	no	no	no	HC
DCA+blood	IL-2	DCA+blood+GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.122	0.522	no	no	no	no	no	no	HC
DCA+blood	IL-2	DCA+blood+GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.122	0.522	no	no	no	no	no	no	HC
DCA+blood	IL-2	DCA+blood+GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.122	0.522	no	no	no	no	no	no	HC
DCA+blood	IL-2	DCA+blood+GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.122	0.522	no	no	no	no	no	no	HC
DCA+blood	IL-2	DCA+blood+GUDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.122	0.522	no	no	no	no	no	no	HC
DCA+blood	IL-2	DCA+blood+GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.122	0.522	no	no	no	no	no	no	HC
DCA+blood	IL-2	"DCA+blood-n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2"	Indirect	serum_bileacids	serum_cytokines	0.122	0.522	no	no	no	no	no	no	HC
DCA+blood	IL-2	DCA+blood+GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.122	0.522	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-2	3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.33	0.522	no	no	no	no	no	no	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-2	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.522	up	up	no	no	no	no	HC
GLCA+stool	IL-2	GLCA+stool-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.617	0.522	no	no	no	no	no	no	HC
GLCA+stool	IL-2	GLCA+stool-iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.617	0.522	no	no	no	no	no	no	HC
GLCA+stool	IL-2	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.617	0.522	no	no	no	no	no	no	HC
GLCA+stool	IL-2	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.617	0.522	no	no	no	no	no	no	HC
GLCA+stool	IL-2	GLCA+stool-iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.617	0.522	no	no	no	no	no	no	HC
GLCA+stool	IL-2	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.617	0.522	no	no	no	no	no	no	HC
GLCA+stool	IL-2	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.617	0.522	no	no	no	no	no	no	HC
GLCA+stool	IL-2	GLCA+stool-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.617	0.522	no	no	no	no	no	no	HC
GLCA+stool	IL-2	GLCA+stool-iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.617	0.522	no	no	no	no	no	no	HC
GLCA+stool	IL-2	"GLCA+stool-LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2"	Indirect	stool_bileacids	serum_cytokines	0.617	0.522	no	no	no	no	no	no	HC
GLCA+stool	IL-2	GLCA+stool-iso-LCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.617	0.522	no	no	no	no	no	no	HC
GLCA+stool	IL-2	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.617	0.522	no	no	no	no	no	no	HC
GLCA+stool	IL-2	GLCA+stool-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.617	0.522	no	no	no	no	no	no	HC
GLCA+stool	IL-2	GLCA+stool-iso-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.617	0.522	no	no	no	no	no	no	HC
GLCA+stool	IL-2	GLCA+stool-LCA+stool-TCA+stool-20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.617	0.522	no	no	no	no	no	no	HC
GLCA+stool	IL-2	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.617	0.522	no	no	no	no	no	no	HC
GLCA+stool	IL-2	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.617	0.522	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-2	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.304	0.522	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-2	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.304	0.522	no	no	no	no	no	no	HC
TCA+stool	IL-2	TCA+stool-20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.458	0.522	no	no	no	no	no	no	HC
HDCA+stool	IL-2	HDCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.176	0.522	no	no	no	no	no	no	HC
HDCA+stool	IL-2	HDCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.176	0.522	no	no	no	no	no	no	HC
HDCA+stool	IL-2	HDCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.176	0.522	no	no	no	no	no	no	HC
HDCA+stool	IL-2	HDCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.176	0.522	no	no	no	no	no	no	HC
HDCA+stool	IL-2	HDCA+stool+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.176	0.522	no	no	no	no	no	no	HC
HDCA+stool	IL-2	HDCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.176	0.522	no	no	no	no	no	no	HC
HDCA+stool	IL-2	HDCA+stool+16:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.176	0.522	no	no	no	no	no	no	HC
HDCA+stool	IL-2	HDCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.176	0.522	no	no	no	no	no	no	HC
HDCA+stool	IL-2	HDCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.176	0.522	no	no	no	no	no	no	HC
HDCA+stool	IL-2	HDCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.176	0.522	no	no	no	no	no	no	HC
HDCA+stool	IL-2	HDCA+stool+20:3/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.176	0.522	no	no	no	no	no	no	HC
Lachnospira	IL-2	Lachnospira-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.279	0.522	no	no	no	no	no	no	HC
Lachnospira	IL-2	Lachnospira-20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.279	0.522	no	no	no	no	no	no	HC
isobutyric acid C4+blood	IL-2	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.0151	0.522	up	up	no	no	no	no	HC
isobutyric acid C4+blood	IL-2	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.0151	0.522	up	up	no	no	no	no	HC
isobutyric acid C4+blood	IL-2	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.0151	0.522	up	up	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool-9-HODE+blood-L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood+TXB2+blood-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood-TXB2+blood-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood-20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool-Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool-9-HODE+blood+GPC+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood+L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool+18:0/20:5-PC+blood-20:0-LPE+blood+d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool+18:0/20:5-PC+blood+18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool+18:0/20:5-PC+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool+18:0/20:5-PC+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool+18:0/20:5-PC+blood+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool+18:0/20:5-PC+blood+18:1/18:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
GCDCA+stool	IL-2	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.0471	0.522	no	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool+GCA+stool-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool+GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool+GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool+GCA+stool+GDCA+stool-TXB2+blood-FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-2	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.522	dn	dn	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Endocrine resistance+Huntington disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Long-term depression+Huntington disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Pancreatic secretion+Huntington disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Aldosterone synthesis and secretion+Huntington disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Cushing syndrome+Huntington disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Endocrine resistance+L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Long-term depression+L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Pancreatic secretion+L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Aldosterone synthesis and secretion+L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter+Arginine and proline metabolism+Biosynthesis of amino acids-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Endocrine resistance+mRNA surveillance pathway+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Long-term depression-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Pancreatic secretion-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Long-term depression+Prion disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Pancreatic secretion+Prion disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Aldosterone synthesis and secretion+Prion disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Endocrine resistance+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Long-term depression+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Endocrine resistance+Parkinson disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Long-term depression+Parkinson disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter+Arginine and proline metabolism-Parkinson disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Pancreatic secretion+Parkinson disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Aldosterone synthesis and secretion+Parkinson disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Cushing syndrome+Parkinson disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Endocrine resistance+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Long-term depression+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter+Arginine and proline metabolism-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Pancreatic secretion+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Cushing syndrome+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Endocrine resistance+RNA degradation+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter+Arginine and proline metabolism-RNA degradation+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Endocrine resistance+Alzheimer disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Long-term depression+Alzheimer disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Pancreatic secretion+Alzheimer disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Aldosterone synthesis and secretion+Alzheimer disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Cushing syndrome+Alzheimer disease+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Phospholipase D signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Endocrine resistance+Thermogenesis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter+Arginine and proline metabolism-Thermogenesis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Endocrine resistance+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Long-term depression+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter+Arginine and proline metabolism-Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Pancreatic secretion+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Cushing syndrome+Amyotrophic lateral sclerosis+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Pancreatic secretion+20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Morphine addiction+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Long-term depression+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Pancreatic secretion+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Aldosterone synthesis and secretion+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Odoribacter	IL-2	Odoribacter-Cushing syndrome+Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.798	0.522	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-2	Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_scfa	serum_cytokines	0.408	0.522	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-2	Isobutyric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_scfa	serum_cytokines	0.408	0.522	no	no	no	no	no	no	HC
Kynurenic acid+stool	IL-2	Kynurenic acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.037	0.522	dn	dn	no	no	no	no	HC
L-Tryptophan+urine	IL-2	L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	urine_cometabolism	serum_cytokines	0.226	0.522	no	no	no	no	no	no	HC
Eggerthella	IL-2	Eggerthella+Bacteroides-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.912	0.522	no	no	no	no	no	no	HC
Anaerotruncus	IL-2	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.904	0.522	no	no	no	no	no	no	HC
Anaerotruncus	IL-2	Anaerotruncus-Gemmiger-Tuberculosis+Graft-versus-host disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.904	0.522	no	no	no	no	no	no	HC
Anaerotruncus	IL-2	Anaerotruncus-Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.904	0.522	no	no	no	no	no	no	HC
Anaerotruncus	IL-2	Anaerotruncus-Gemmiger-Tuberculosis-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.904	0.522	no	no	no	no	no	no	HC
Anaerotruncus	IL-2	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Viral myocarditis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.904	0.522	no	no	no	no	no	no	HC
Anaerotruncus	IL-2	Anaerotruncus-Gemmiger-Tuberculosis+Viral myocarditis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.904	0.522	no	no	no	no	no	no	HC
Anaerotruncus	IL-2	Anaerotruncus-Gemmiger-GPC+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.904	0.522	no	no	no	no	no	no	HC
Anaerotruncus	IL-2	Anaerotruncus-Gemmiger-20:1-LPA+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.904	0.522	no	no	no	no	no	no	HC
Anaerotruncus	IL-2	Anaerotruncus-Gemmiger-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.904	0.522	no	no	no	no	no	no	HC
Anaerotruncus	IL-2	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Allograft rejection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.904	0.522	no	no	no	no	no	no	HC
Anaerotruncus	IL-2	Anaerotruncus-Gemmiger-Tuberculosis+Allograft rejection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.904	0.522	no	no	no	no	no	no	HC
Anaerotruncus	IL-2	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.904	0.522	no	no	no	no	no	no	HC
Anaerotruncus	IL-2	Anaerotruncus-Gemmiger-Tuberculosis+Autoimmune thyroid disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.904	0.522	no	no	no	no	no	no	HC
Anaerotruncus	IL-2	Anaerotruncus-Gemmiger+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.904	0.522	no	no	no	no	no	no	HC
Anaerotruncus	IL-2	Anaerotruncus-Gemmiger-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.904	0.522	no	no	no	no	no	no	HC
Anaerostipes	IL-2	Anaerostipes-20:0+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.568	0.522	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-2	Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_scfa	serum_cytokines	0.343	0.522	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-2	Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_scfa	serum_cytokines	0.343	0.522	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-2	Isovaleric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_scfa	serum_cytokines	0.343	0.522	no	no	no	no	no	no	HC
Paraprevotella	IL-2	Paraprevotella-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.118	0.522	no	no	no	no	no	no	HC
Paraprevotella	IL-2	Paraprevotella+AA+blood-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.118	0.522	no	no	no	no	no	no	HC
Homovanillic acid+urine	IL-2	Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	urine_cometabolism	serum_cytokines	0.45	0.522	no	no	no	no	no	no	HC
Homovanillic acid+urine	IL-2	Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	urine_cometabolism	serum_cytokines	0.45	0.522	no	no	no	no	no	no	HC
TDCA+blood	IL-2	TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.155	0.522	no	up	no	no	no	no	HC
iso-LCA+blood	IL-2	iso-LCA+blood-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.507	0.522	no	no	no	no	no	no	HC
iso-LCA+blood	IL-2	iso-LCA+blood-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.507	0.522	no	no	no	no	no	no	HC
iso-LCA+blood	IL-2	iso-LCA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.507	0.522	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IL-2	¦Ø-MCA+stool-Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.919	0.522	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IL-2	¦Ø-MCA+stool-Acetic acid+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.919	0.522	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-2	Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.785	0.522	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-2	Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.785	0.522	no	no	no	no	no	no	HC
Gemmiger	IL-2	Gemmiger-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	HC
Gemmiger	IL-2	Gemmiger-Tuberculosis+Graft-versus-host disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	HC
Gemmiger	IL-2	Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	HC
Gemmiger	IL-2	Gemmiger-Tuberculosis-Diabetic cardiomyopathy+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	HC
Gemmiger	IL-2	Gemmiger-Staphylococcus aureus infection+Viral myocarditis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	HC
Gemmiger	IL-2	Gemmiger-Tuberculosis+Viral myocarditis-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	HC
Gemmiger	IL-2	Gemmiger-GPC+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	HC
Gemmiger	IL-2	Gemmiger-20:1-LPA+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	HC
Gemmiger	IL-2	Gemmiger-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	HC
Gemmiger	IL-2	Gemmiger-Staphylococcus aureus infection+Allograft rejection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	HC
Gemmiger	IL-2	Gemmiger-Tuberculosis+Allograft rejection-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	HC
Gemmiger	IL-2	Gemmiger-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	HC
Gemmiger	IL-2	Gemmiger-Tuberculosis+Autoimmune thyroid disease-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	HC
Gemmiger	IL-2	Gemmiger+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	HC
Gemmiger	IL-2	Gemmiger-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.595	0.522	no	no	no	no	no	no	HC
GDCA+stool	IL-2	GDCA+stool-TXB2+blood-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.656	0.522	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-2	L-Tyrosine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.44	0.522	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-2	L-Tyrosine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.44	0.522	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-2	L-Tyrosine+stool+PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.44	0.522	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-2	L-Tyrosine+stool+20:1-LPA+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.44	0.522	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-2	L-Tyrosine+stool+8-HETE+blood-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.44	0.522	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-2	L-Tyrosine+stool-12-ketoDCA+blood-AA+blood-FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.44	0.522	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-2	L-Tyrosine+stool+8-HETE+blood+AA+blood-FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.44	0.522	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-2	L-Tyrosine+stool+8-HETE+blood+TXB2+blood-FGF basic-IL-13-IL-2	Indirect	stool_cometabolism	serum_cytokines	0.44	0.522	no	no	no	no	no	no	HC
CDCA+stool	IL-2	CDCA+stool+18:3n3+blood+AA+blood-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.663	0.522	no	no	no	no	no	no	HC
CDCA+stool	IL-2	CDCA+stool+TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.663	0.522	no	no	no	no	no	no	HC
CDCA+stool	IL-2	CDCA+stool+nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.663	0.522	no	no	no	no	no	no	HC
CDCA+stool	IL-2	CDCA+stool+HCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.663	0.522	no	no	no	no	no	no	HC
CDCA+stool	IL-2	CDCA+stool+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.663	0.522	no	no	no	no	no	no	HC
CDCA+stool	IL-2	CDCA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.663	0.522	no	no	no	no	no	no	HC
CDCA+stool	IL-2	CDCA+stool-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.663	0.522	no	no	no	no	no	no	HC
CA+stool	IL-2	CA+stool+nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.827	0.522	no	no	no	no	no	no	HC
CA+stool	IL-2	CA+stool+HCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.827	0.522	no	no	no	no	no	no	HC
CA+stool	IL-2	CA+stool-ACA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.827	0.522	no	no	no	no	no	no	HC
CA+stool	IL-2	CA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.827	0.522	no	no	no	no	no	no	HC
CA+stool	IL-2	CA+stool+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.827	0.522	no	no	no	no	no	no	HC
CA+stool	IL-2	CA+stool-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.827	0.522	no	no	no	no	no	no	HC
CA+stool	IL-2	CA+stool+GDCA+stool-TXB2+blood-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.827	0.522	no	no	no	no	no	no	HC
CA+stool	IL-2	CA+stool+TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.827	0.522	no	no	no	no	no	no	HC
CA+stool	IL-2	CA+stool-18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.827	0.522	no	no	no	no	no	no	HC
HDCA+blood	IL-2	HDCA+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.483	0.522	no	no	no	no	no	no	HC
HDCA+blood	IL-2	HDCA+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.483	0.522	no	no	no	no	no	no	HC
HDCA+blood	IL-2	HDCA+blood+SFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.483	0.522	no	no	no	no	no	no	HC
HDCA+blood	IL-2	HDCA+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.483	0.522	no	no	no	no	no	no	HC
UDCA+stool	IL-2	UDCA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.266	0.522	no	no	no	no	no	no	HC
UDCA+stool	IL-2	UDCA+stool+18:3n3+blood+AA+blood-FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.266	0.522	no	no	no	no	no	no	HC
LCA+blood	IL-2	LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.884	0.522	no	no	no	no	no	no	HC
nutriCA+stool	IL-2	nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13-IL-2	Indirect	stool_bileacids	serum_cytokines	0.481	0.522	no	no	no	no	no	no	HC
GDCA+blood	IL-2	GDCA+blood+TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.632	0.522	no	no	no	no	no	no	HC
P-hydroxyhippuric acid+urine	IL-2	P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	urine_cometabolism	serum_cytokines	0.436	0.522	no	no	no	no	no	no	HC
acetic acid C2+blood	IL-2	acetic acid C2+blood-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.000193	0.522	up	dn	no	no	no	no	HC
isovaleric acid iso-C5+blood	IL-2	isovaleric acid iso-C5+blood+Sarcosine+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	serum_scfa	serum_cytokines	0.117	0.522	no	no	no	no	no	no	HC
L-Phenylalanine+urine	IL-2	L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	urine_cometabolism	serum_cytokines	0.0908	0.522	no	up	no	no	no	no	HC
Clostridium	IL-2	Clostridium+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.925	0.522	no	no	no	no	no	no	HC
Clostridium	IL-2	Clostridium-L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.925	0.522	no	no	no	no	no	no	HC
12-ketoDCA+blood	IL-2	12-ketoDCA+blood-AA+blood-FGF basic-IL-13-IL-2	Indirect	serum_bileacids	serum_cytokines	0.517	0.522	no	no	no	no	no	no	HC
Butyricicoccus	IL-2	Butyricicoccus+d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.852	0.522	no	no	no	no	no	no	HC
3-Hydroxy-L-kynurenine+urine	IL-2	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2	Indirect	urine_cometabolism	serum_cytokines	0.401	0.522	no	no	no	no	no	no	HC
Wautersiella	IL-2	Wautersiella+Butyricicoccus+d18:1-22:0-SM+blood+FGF basic-IL-13-IL-2	Indirect	Genus	serum_cytokines	0.289	0.522	no	no	no	no	no	no	HC
Blautia	TNF-a	Blautia+Peroxisome+Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	HC
Blautia	TNF-a	Blautia-Chemical carcinogenesis - receptor activation+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	HC
Blautia	TNF-a	Blautia-18:1-LPE+blood+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	HC
Blautia	TNF-a	Blautia+16:0/20:5-PC+blood-18:1-LPC+blood+TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	HC
Blautia	TNF-a	Blautia+16:0/20:5-PC+blood+EPA+blood-TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	HC
Blautia	TNF-a	Blautia+16:0/20:5-PC+blood-Choline+blood+TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	HC
Blautia	TNF-a	Blautia+Peroxisome+Longevity regulating pathway - multiple species-TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	HC
Blautia	TNF-a	Blautia+Peroxisome-20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	HC
Blautia	TNF-a	Blautia-18:2-LPC+blood+20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	HC
Blautia	TNF-a	Blautia+Arginine and proline metabolism+Biosynthesis of amino acids-TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	HC
Blautia	TNF-a	Blautia-18:1-LPE+blood-TXB2+blood-TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	HC
Blautia	TNF-a	Blautia+Peroxisome+18:0/18:0-PS+blood-TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	HC
Blautia	TNF-a	Blautia+Arginine and proline metabolism-RNA degradation+TNF-a	Indirect	Genus	serum_cytokines	1.36E-05	0.613	up	dn	dn	no	no	no	HC
Parabacteroides	TNF-a	Parabacteroides+18:0/22:6-PA+blood-TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	HC
Parabacteroides	TNF-a	Parabacteroides+Biosynthesis of amino acids-TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	HC
Parabacteroides	TNF-a	Parabacteroides-RNA degradation+TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	HC
Parabacteroides	TNF-a	Parabacteroides+Carbon metabolism-TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	HC
Parabacteroides	TNF-a	Parabacteroides+Glycolysis / Gluconeogenesis-TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	HC
Parabacteroides	TNF-a	Parabacteroides-Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	HC
Parabacteroides	TNF-a	Parabacteroides-mRNA surveillance pathway+TNF-a	Indirect	Genus	serum_cytokines	4.19E-05	0.613	no	up	up	no	no	no	HC
Dorea	TNF-a	Dorea-18:2-LPC+blood+20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Dorea	TNF-a	Dorea-VEGF signaling pathway+18:1-LPC+blood+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Dorea	TNF-a	Dorea-Fc epsilon RI signaling pathway+18:1-LPC+blood+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Dorea	TNF-a	Dorea-Endocrine resistance+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Dorea	TNF-a	Dorea-Chemical carcinogenesis - receptor activation+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Dorea	TNF-a	"Dorea-Growth hormone synthesis, secretion and action+L-Homocystine+blood+TNF-a"	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Dorea	TNF-a	Dorea-Endocrine resistance+mRNA surveillance pathway+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Dorea	TNF-a	Dorea-Endocrine resistance+RNA degradation+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Dorea	TNF-a	Dorea-VEGF signaling pathway+Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Dorea	TNF-a	Dorea-Thyroid hormone signaling pathway-Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Dorea	TNF-a	Dorea-Fc epsilon RI signaling pathway+Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Dorea	TNF-a	Dorea-16:0-LPC+blood+TXB2+blood-TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Dorea	TNF-a	Dorea-VEGF signaling pathway+B cell receptor signaling pathway+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Dorea	TNF-a	Dorea+Legionellosis+Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Dorea	TNF-a	Dorea-Fc epsilon RI signaling pathway-Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Dorea	TNF-a	Dorea-VEGF signaling pathway+Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Dorea	TNF-a	Dorea-Fc epsilon RI signaling pathway+Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Dorea	TNF-a	"Dorea-Growth hormone synthesis, secretion and action+Pathways in cancer+TNF-a"	Indirect	Genus	serum_cytokines	0.00362	0.613	up	no	dn	no	no	no	HC
Faecalibacterium	TNF-a	Faecalibacterium-Staphylococcus aureus infection-Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.0039	0.613	no	dn	dn	no	no	no	HC
Faecalibacterium	TNF-a	Faecalibacterium+4-hydroxybenzoic acid+stool-EPA+blood-TNF-a	Indirect	Genus	serum_cytokines	0.0039	0.613	no	dn	dn	no	no	no	HC
Faecalibacterium	TNF-a	Faecalibacterium+4-hydroxybenzoic acid+stool-L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.0039	0.613	no	dn	dn	no	no	no	HC
isocapric acid iso-C6+blood	TNF-a	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+L-Citrulline+blood+TNF-a	Indirect	serum_scfa	serum_cytokines	0.0458	0.613	no	no	dn	no	no	no	HC
Bacteroides	TNF-a	Bacteroides-L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	HC
Bacteroides	TNF-a	Bacteroides+Biosynthesis of amino acids-TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	HC
Bacteroides	TNF-a	Bacteroides+TXB2+blood-TNF-a	Indirect	Genus	serum_cytokines	0.000267	0.613	dn	dn	up	no	no	no	HC
Propionic acid+stool	TNF-a	Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0436	0.613	dn	no	up	no	no	no	HC
Propionic acid+stool	TNF-a	Propionic acid+stool+16:0/18:2-PI+blood-18:1-LPC+blood+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0436	0.613	dn	no	up	no	no	no	HC
Propionic acid+stool	TNF-a	Propionic acid+stool+16:0/18:2-PI+blood-20:1+blood+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0436	0.613	dn	no	up	no	no	no	HC
[Ruminococcus]	TNF-a	[Ruminococcus]+nutriCA+stool-L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	HC
[Ruminococcus]	TNF-a	[Ruminococcus]-18:0/20:4-PI+blood+18:1-LPC+blood+TNF-a	Indirect	Genus	serum_cytokines	0.0679	0.613	no	no	dn	no	no	no	HC
Acetic acid+stool	TNF-a	Acetic acid+stool-L-Homocystine+blood+TNF-a	Indirect	stool_scfa	serum_cytokines	0.0656	0.613	dn	no	no	no	no	no	HC
Alistipes	TNF-a	Alistipes-Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.0114	0.613	no	up	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+VEGF signaling pathway+Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+cAMP signaling pathway+Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Sphingolipid signaling pathway+Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Prolactin signaling pathway+Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas-Glutathione metabolism-Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Neurotrophin signaling pathway+Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	"Butyricimonas+Parathyroid hormone synthesis, secretion and action+Insulin resistance+TNF-a"	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+VEGF signaling pathway+Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Spinocerebellar ataxia+Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Prion disease+Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+cAMP signaling pathway+Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Adrenergic signaling in cardiomyocytes+Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas-Leishmaniasis-Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Sphingolipid signaling pathway+Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Prolactin signaling pathway+Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas-Glutathione metabolism-Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Calcium signaling pathway+Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Neurotrophin signaling pathway+Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Dopaminergic synapse+Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Non-alcoholic fatty liver disease+Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas-Glutathione metabolism-NF-kappa B signaling pathway+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+20:5/18:0-PC+blood+EPA+blood-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Spinocerebellar ataxia+Small cell lung cancer+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Neurotrophin signaling pathway+Small cell lung cancer+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Colorectal cancer+Small cell lung cancer+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+PD-L1 expression and PD-1 checkpoint pathway in cancer+L-Citrulline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Prion disease+20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Chagas disease+20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Non-alcoholic fatty liver disease+20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+18:1/18:1-PC+blood+20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Diabetic cardiomyopathy+20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Pancreatic secretion+20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Prion disease+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+cAMP signaling pathway+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Adrenergic signaling in cardiomyocytes+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Calcium signaling pathway+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Neurotrophin signaling pathway+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Dopaminergic synapse+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Chagas disease+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Long-term depression+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Non-alcoholic fatty liver disease+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Diabetic cardiomyopathy+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	"Butyricimonas+Parathyroid hormone synthesis, secretion and action+L-Homocystine+blood+TNF-a"	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Colorectal cancer+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Pancreatic secretion+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Prion disease-TXB2+blood-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+16:0-LPC+blood+TXB2+blood-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Neurotrophin signaling pathway-TXB2+blood-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Non-alcoholic fatty liver disease-TXB2+blood-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Diabetic cardiomyopathy-TXB2+blood-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+cAMP signaling pathway-18:0/18:0-PS+blood-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Adrenergic signaling in cardiomyocytes-18:0/18:0-PS+blood-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Dopaminergic synapse-18:0/18:0-PS+blood-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Chagas disease-18:0/18:0-PS+blood-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Long-term depression-18:0/18:0-PS+blood-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+cAMP signaling pathway+Choline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Non-alcoholic fatty liver disease+Choline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Colorectal cancer+Choline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+VEGF signaling pathway+B cell receptor signaling pathway+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Prevotella-B cell receptor signaling pathway+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas-Glutathione metabolism-B cell receptor signaling pathway+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+cAMP signaling pathway-Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas-Leishmaniasis+Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Calcium signaling pathway-Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Phospholipase D signaling pathway-Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Neurotrophin signaling pathway-Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Long-term depression-Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Non-alcoholic fatty liver disease-Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Colorectal cancer-Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Pancreatic secretion-Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+VEGF signaling pathway+18:1-LPC+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+cAMP signaling pathway+18:1-LPC+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Sphingolipid signaling pathway+18:1-LPC+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Neurotrophin signaling pathway+18:1-LPC+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Butyricimonas	TNF-a	Butyricimonas+Diabetic cardiomyopathy+18:1-LPC+blood+TNF-a	Indirect	Genus	serum_cytokines	0.17	0.613	no	no	no	no	no	no	HC
Collinsella	TNF-a	Collinsella-TNF-a	Direct	Genus	serum_cytokines	0.128	0.613	no	no	no	no	no	no	HC
iso-DCA+stool	TNF-a	iso-DCA+stool-nutriCA+stool-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.155	0.613	no	no	no	no	no	no	HC
LCA+stool	TNF-a	LCA+stool+16:0/18:1-PC+blood+18:0/22:6-PA+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.314	0.613	no	no	no	no	no	no	HC
LCA+stool	TNF-a	LCA+stool+18:0/16:0-PC+blood+18:0/22:6-PA+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.314	0.613	no	no	no	no	no	no	HC
LCA+stool	TNF-a	LCA+stool-nutriCA+stool-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.314	0.613	no	no	no	no	no	no	HC
LCA+stool	TNF-a	LCA+stool-TCA+stool-20:0+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.314	0.613	no	no	no	no	no	no	HC
LCA+stool	TNF-a	LCA+stool-DMG+blood+L-Citrulline+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.314	0.613	no	no	no	no	no	no	HC
LCA+stool	TNF-a	LCA+stool-TCA+stool-Choline+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.314	0.613	no	no	no	no	no	no	HC
Akkermansia	TNF-a	Akkermansia-Wnt signaling pathway+Choline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	HC
Akkermansia	TNF-a	Akkermansia-Ribosome+Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	HC
Akkermansia	TNF-a	Akkermansia-Ribosome+mRNA surveillance pathway+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	HC
Akkermansia	TNF-a	Akkermansia-Ribosome+RNA degradation+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	HC
Akkermansia	TNF-a	Akkermansia-Acetic acid+stool-L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	HC
Akkermansia	TNF-a	Akkermansia+Pertussis-Small cell lung cancer+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	HC
Akkermansia	TNF-a	Akkermansia-Wnt signaling pathway-Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	HC
Akkermansia	TNF-a	Akkermansia-Wnt signaling pathway+Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.23	0.613	no	no	no	no	no	no	HC
Bifidobacterium	TNF-a	Bifidobacterium-TNF-a	Direct	Genus	serum_cytokines	0.105	0.613	no	dn	no	no	no	no	HC
Ruminococcus	TNF-a	Ruminococcus-Biosynthesis of amino acids-TNF-a	Indirect	Genus	serum_cytokines	0.335	0.613	no	no	no	no	no	no	HC
GCDCA+blood	TNF-a	GCDCA+blood+L-Alanine+blood+L-Asparagine+blood+L-Citrulline+blood+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.31	0.613	no	no	no	no	no	no	HC
[Prevotella]	TNF-a	[Prevotella]-18:0/22:6-PC+blood-20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	0.367	0.613	no	no	no	no	no	no	HC
[Prevotella]	TNF-a	[Prevotella]-Glutamatergic synapse-Small cell lung cancer+TNF-a	Indirect	Genus	serum_cytokines	0.367	0.613	no	no	no	no	no	no	HC
[Prevotella]	TNF-a	[Prevotella]+24:0+blood-L-Citrulline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.367	0.613	no	no	no	no	no	no	HC
[Prevotella]	TNF-a	[Prevotella]-Gap junction-L-Citrulline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.367	0.613	no	no	no	no	no	no	HC
[Prevotella]	TNF-a	[Prevotella]-Gap junction-B cell receptor signaling pathway+TNF-a	Indirect	Genus	serum_cytokines	0.367	0.613	no	no	no	no	no	no	HC
[Prevotella]	TNF-a	[Prevotella]-18:0/22:6-PC+blood+EPA+blood-TNF-a	Indirect	Genus	serum_cytokines	0.367	0.613	no	no	no	no	no	no	HC
[Prevotella]	TNF-a	[Prevotella]-18:0/22:6-PC+blood+TXB2+blood-TNF-a	Indirect	Genus	serum_cytokines	0.367	0.613	no	no	no	no	no	no	HC
[Prevotella]	TNF-a	"[Prevotella]-Growth hormone synthesis, secretion and action+L-Homocystine+blood+TNF-a"	Indirect	Genus	serum_cytokines	0.367	0.613	no	no	no	no	no	no	HC
[Prevotella]	TNF-a	[Prevotella]-Aldosterone synthesis and secretion+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.367	0.613	no	no	no	no	no	no	HC
[Prevotella]	TNF-a	[Prevotella]+24:0+blood-L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.367	0.613	no	no	no	no	no	no	HC
[Prevotella]	TNF-a	"[Prevotella]-Growth hormone synthesis, secretion and action+Pathways in cancer+TNF-a"	Indirect	Genus	serum_cytokines	0.367	0.613	no	no	no	no	no	no	HC
[Prevotella]	TNF-a	[Prevotella]-Aldosterone synthesis and secretion+Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.367	0.613	no	no	no	no	no	no	HC
ACA+blood	TNF-a	ACA+blood-d18:1-14:0-SM+blood+d18:1-14:1-SM+blood-L-Citrulline+blood+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.338	0.613	no	no	no	no	no	no	HC
ACA+blood	TNF-a	ACA+blood-d18:1-14:0-SM+blood+d18:1-20:0-SM+blood-L-Citrulline+blood+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.338	0.613	no	no	no	no	no	no	HC
ACA+blood	TNF-a	ACA+blood-d18:1-14:0-SM+blood+d18:1-20:0-SM+blood-L-Homocystine+blood+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.338	0.613	no	no	no	no	no	no	HC
DCA+stool	TNF-a	DCA+stool-8-HETE+blood+TXB2+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	HC
DCA+stool	TNF-a	DCA+stool-20:1-LPA+blood-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	HC
DCA+stool	TNF-a	DCA+stool-8-HETE+blood-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	HC
DCA+stool	TNF-a	DCA+stool-DMG+blood+L-Citrulline+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.195	0.613	no	no	no	no	no	no	HC
Butyric acid+stool	TNF-a	Butyric acid+stool+16:0/16:0-PC+blood+EPA+blood-TNF-a	Indirect	stool_scfa	serum_cytokines	0.102	0.613	dn	no	no	no	no	no	HC
Butyric acid+stool	TNF-a	Butyric acid+stool+16:0/16:0-PC+blood+18:0/22:6-PA+blood-TNF-a	Indirect	stool_scfa	serum_cytokines	0.102	0.613	dn	no	no	no	no	no	HC
4-hydroxybenzoic acid+stool	TNF-a	4-hydroxybenzoic acid+stool-L-Homocystine+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.613	no	dn	no	no	no	no	HC
4-hydroxybenzoic acid+stool	TNF-a	4-hydroxybenzoic acid+stool-EPA+blood-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.613	no	dn	no	no	no	no	HC
GCA+blood	TNF-a	GCA+blood+L-Alanine+blood+L-Asparagine+blood+L-Citrulline+blood+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.16	0.613	no	no	no	no	no	no	HC
ACA+stool	TNF-a	ACA+stool-Acetic acid+stool-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.417	0.613	no	no	no	no	no	no	HC
CDCA+blood	TNF-a	CDCA+blood-Creatinine+blood+L-Citrulline+blood+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.506	0.613	no	no	no	no	no	no	HC
capric acid C6+blood	TNF-a	capric acid C6+blood-Cystine+blood+L-Arginine+blood+L-Citrulline+blood+TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	HC
capric acid C6+blood	TNF-a	capric acid C6+blood-Cystine+blood+L-Asparagine+blood+L-Citrulline+blood+TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	HC
capric acid C6+blood	TNF-a	capric acid C6+blood-Cystine+blood-d18:1-14:1-SM+blood-L-Citrulline+blood+TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	HC
capric acid C6+blood	TNF-a	capric acid C6+blood-Cystine+blood+L-Aspartic acid+blood+TXB2+blood-TNF-a	Indirect	serum_scfa	serum_cytokines	0.433	0.613	no	no	no	no	no	no	HC
Prevotella	TNF-a	Prevotella-B cell receptor signaling pathway+TNF-a	Indirect	Genus	serum_cytokines	0.287	0.613	no	no	no	no	no	no	HC
HCA+stool	TNF-a	HCA+stool-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.155	0.613	no	no	no	no	no	no	HC
Roseburia	TNF-a	Roseburia-TNF-a	Direct	Genus	serum_cytokines	0.495	0.613	no	no	no	no	no	no	HC
12-ketoDCA+stool	TNF-a	12-ketoDCA+stool-15-HETE+blood-18:0/18:0-PS+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.505	0.613	no	no	no	no	no	no	HC
12-ketoDCA+stool	TNF-a	12-ketoDCA+stool-15-HETE+blood+20:1+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.505	0.613	no	no	no	no	no	no	HC
L-Tryptophan+stool	TNF-a	L-Tryptophan+stool+16:0/22:6-PE+blood+18:0/18:0-PS+blood-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.557	0.613	no	no	no	no	no	no	HC
L-Tryptophan+stool	TNF-a	L-Tryptophan+stool+Phenylacetic acid+stool+20:1+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.557	0.613	no	no	no	no	no	no	HC
L-Tryptophan+stool	TNF-a	L-Tryptophan+stool+Phenylacetic acid+stool+20:0+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.557	0.613	no	no	no	no	no	no	HC
L-Tryptophan+stool	TNF-a	L-Tryptophan+stool-12-ketoDCA+blood-18:1-LPC+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.557	0.613	no	no	no	no	no	no	HC
L-Tryptophan+stool	TNF-a	L-Tryptophan+stool+Phenylacetic acid+stool+18:1-LPC+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.557	0.613	no	no	no	no	no	no	HC
CA+blood	TNF-a	CA+blood+CDCA+blood-Creatinine+blood+L-Citrulline+blood+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.606	0.613	no	no	no	no	no	no	HC
GUDCA+stool	TNF-a	GUDCA+stool+Phenylacetic acid+stool+20:1+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0085	0.613	no	dn	no	no	no	no	HC
GUDCA+stool	TNF-a	GUDCA+stool+Phenylacetic acid+stool+18:1-LPC+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0085	0.613	no	dn	no	no	no	no	HC
GUDCA+stool	TNF-a	GUDCA+stool+Phenylacetic acid+stool+20:0+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0085	0.613	no	dn	no	no	no	no	HC
L-Phenylalanine+stool	TNF-a	L-Phenylalanine+stool+Phenylacetic acid+stool+18:1-LPC+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.398	0.613	no	no	no	no	no	no	HC
L-Phenylalanine+stool	TNF-a	L-Phenylalanine+stool-12-ketoDCA+blood-18:1-LPC+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.398	0.613	no	no	no	no	no	no	HC
L-Phenylalanine+stool	TNF-a	L-Phenylalanine+stool+Phenylacetic acid+stool+20:0+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.398	0.613	no	no	no	no	no	no	HC
L-Phenylalanine+stool	TNF-a	L-Phenylalanine+stool+Phenylacetic acid+stool+20:1+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.398	0.613	no	no	no	no	no	no	HC
L-Phenylalanine+stool	TNF-a	L-Phenylalanine+stool+16:0/22:6-PE+blood+18:0/18:0-PS+blood-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.398	0.613	no	no	no	no	no	no	HC
L-Phenylalanine+stool	TNF-a	L-Phenylalanine+stool-18:3n6+blood-Choline+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.398	0.613	no	no	no	no	no	no	HC
butyric acid C4+blood	TNF-a	butyric acid C4+blood+heptanoic acid C7+blood+L-Asparagine+blood+L-Citrulline+blood+TNF-a	Indirect	serum_scfa	serum_cytokines	0.407	0.613	no	no	no	no	no	no	HC
butyric acid C4+blood	TNF-a	butyric acid C4+blood+Cystine+blood+L-Asparagine+blood+L-Citrulline+blood+TNF-a	Indirect	serum_scfa	serum_cytokines	0.407	0.613	no	no	no	no	no	no	HC
butyric acid C4+blood	TNF-a	butyric acid C4+blood+Cystine+blood-d18:1-14:1-SM+blood-L-Citrulline+blood+TNF-a	Indirect	serum_scfa	serum_cytokines	0.407	0.613	no	no	no	no	no	no	HC
butyric acid C4+blood	TNF-a	butyric acid C4+blood+Cystine+blood+L-Arginine+blood+L-Citrulline+blood+TNF-a	Indirect	serum_scfa	serum_cytokines	0.407	0.613	no	no	no	no	no	no	HC
butyric acid C4+blood	TNF-a	butyric acid C4+blood+Cystine+blood+L-Aspartic acid+blood+TXB2+blood-TNF-a	Indirect	serum_scfa	serum_cytokines	0.407	0.613	no	no	no	no	no	no	HC
GCA+stool	TNF-a	GCA+stool+16:0/18:0-PS+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0809	0.613	no	no	no	no	no	no	HC
Coprococcus	TNF-a	Coprococcus+Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.612	0.613	no	no	no	no	no	no	HC
Coprococcus	TNF-a	Coprococcus-18:1-LPC+blood+TNF-a	Indirect	Genus	serum_cytokines	0.612	0.613	no	no	no	no	no	no	HC
Coprococcus	TNF-a	Coprococcus-Choline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.612	0.613	no	no	no	no	no	no	HC
Oscillospira	TNF-a	Oscillospira+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.62	0.613	no	no	no	no	no	no	HC
HCA+blood	TNF-a	HCA+blood-L-2-Aminobutyric acid+blood+L-Arginine+blood+L-Citrulline+blood+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.544	0.613	no	no	no	no	no	no	HC
iso-LCA+stool	TNF-a	iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.72	0.613	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	TNF-a	2-methyl-butyric acid m-C4+blood+20:1+blood+TNF-a	Indirect	serum_scfa	serum_cytokines	0.262	0.613	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	TNF-a	3-(3-Hydroxyphenyl)propanoic acid+stool+14:0+blood-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.33	0.613	no	no	no	no	no	no	HC
GLCA+stool	TNF-a	GLCA+stool-LCA+stool-nutriCA+stool-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.617	0.613	no	no	no	no	no	no	HC
GLCA+stool	TNF-a	GLCA+stool-iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.617	0.613	no	no	no	no	no	no	HC
GLCA+stool	TNF-a	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+18:0/22:6-PA+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.617	0.613	no	no	no	no	no	no	HC
GLCA+stool	TNF-a	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+18:0/22:6-PA+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.617	0.613	no	no	no	no	no	no	HC
GLCA+stool	TNF-a	GLCA+stool-LCA+stool-DMG+blood+L-Citrulline+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.617	0.613	no	no	no	no	no	no	HC
GLCA+stool	TNF-a	GLCA+stool-LCA+stool-TCA+stool-Choline+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.617	0.613	no	no	no	no	no	no	HC
GLCA+stool	TNF-a	GLCA+stool-LCA+stool-TCA+stool-20:0+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.617	0.613	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	TNF-a	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+18:1-LPC+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.613	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	TNF-a	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+20:1+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.613	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	TNF-a	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+20:0+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.304	0.613	no	no	no	no	no	no	HC
TCA+stool	TNF-a	TCA+stool-20:0+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.458	0.613	no	no	no	no	no	no	HC
TCA+stool	TNF-a	TCA+stool-Choline+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.458	0.613	no	no	no	no	no	no	HC
HDCA+stool	TNF-a	HDCA+stool-nutriCA+stool-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.176	0.613	no	no	no	no	no	no	HC
HDCA+stool	TNF-a	HDCA+stool+16:0/18:1-PC+blood+18:0/22:6-PA+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.176	0.613	no	no	no	no	no	no	HC
HDCA+stool	TNF-a	HDCA+stool+18:0/16:0-PC+blood+18:0/22:6-PA+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.176	0.613	no	no	no	no	no	no	HC
Lachnospira	TNF-a	Lachnospira-20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	HC
Lachnospira	TNF-a	Lachnospira-18:1-LPC+blood+TNF-a	Indirect	Genus	serum_cytokines	0.279	0.613	no	no	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool+18:0/20:5-PC+blood+22:0/16:0-PE+blood+EPA+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool+18:0/20:5-PC+blood+20:5/18:0-PC+blood+EPA+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool+18:0/20:5-PC+blood+20:1/20:4-PC+blood+EPA+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood+EPA+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood+TXB2+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood-TXB2+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood-20:0+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool-Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool-9-HODE+blood+GPC+blood-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood+L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:1+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool+20:1+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool+20:1+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-18:1-LPC+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool+18:1-LPC+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool+18:1-LPC+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
GCDCA+stool	TNF-a	GCDCA+stool-9-HODE+blood-L-Asparagine+blood+L-Citrulline+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.0471	0.613	no	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	TNF-a	5-Hydroxytryptamine+stool+GCA+stool+16:0/18:0-PS+blood-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.613	dn	dn	no	no	no	no	HC
Odoribacter	TNF-a	Odoribacter-Gap junction-B cell receptor signaling pathway+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	HC
Odoribacter	TNF-a	Odoribacter-Endocrine resistance+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	HC
Odoribacter	TNF-a	Odoribacter-Long-term depression+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	HC
Odoribacter	TNF-a	Odoribacter-Pancreatic secretion+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	HC
Odoribacter	TNF-a	Odoribacter-Aldosterone synthesis and secretion+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	HC
Odoribacter	TNF-a	Odoribacter-Gap junction-L-Citrulline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	HC
Odoribacter	TNF-a	Odoribacter+Inflammatory bowel disease+L-Citrulline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	HC
Odoribacter	TNF-a	Odoribacter+Arginine and proline metabolism+Biosynthesis of amino acids-TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	HC
Odoribacter	TNF-a	Odoribacter-Endocrine resistance+mRNA surveillance pathway+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	HC
Odoribacter	TNF-a	Odoribacter-Long-term depression-18:0/18:0-PS+blood-TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	HC
Odoribacter	TNF-a	Odoribacter-Long-term depression-Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	HC
Odoribacter	TNF-a	Odoribacter-Phospholipase D signaling pathway-Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	HC
Odoribacter	TNF-a	Odoribacter-Pancreatic secretion-Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	HC
Odoribacter	TNF-a	Odoribacter-Endocrine resistance+RNA degradation+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	HC
Odoribacter	TNF-a	Odoribacter+Arginine and proline metabolism-RNA degradation+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	HC
Odoribacter	TNF-a	Odoribacter-Pancreatic secretion+20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	HC
Odoribacter	TNF-a	Odoribacter-Aldosterone synthesis and secretion+Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.798	0.613	no	no	no	no	no	no	HC
Isobutyric acid+stool	TNF-a	Isobutyric acid+stool+Phenylacetic acid+stool+20:1+blood+TNF-a	Indirect	stool_scfa	serum_cytokines	0.408	0.613	no	no	no	no	no	no	HC
Isobutyric acid+stool	TNF-a	Isobutyric acid+stool+Phenylacetic acid+stool+18:1-LPC+blood+TNF-a	Indirect	stool_scfa	serum_cytokines	0.408	0.613	no	no	no	no	no	no	HC
Isobutyric acid+stool	TNF-a	Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+TNF-a	Indirect	stool_scfa	serum_cytokines	0.408	0.613	no	no	no	no	no	no	HC
Kynurenic acid+stool	TNF-a	Kynurenic acid+stool-nutriCA+stool-L-Homocystine+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.037	0.613	dn	dn	no	no	no	no	HC
Eggerthella	TNF-a	Eggerthella-Gemmiger-TNF-a	Indirect	Genus	serum_cytokines	0.912	0.613	no	no	no	no	no	no	HC
Anaerotruncus	TNF-a	Anaerotruncus-Gemmiger-TNF-a	Indirect	Genus	serum_cytokines	0.904	0.613	no	no	no	no	no	no	HC
Anaerostipes	TNF-a	Anaerostipes-20:1+blood+TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	HC
Anaerostipes	TNF-a	Anaerostipes-20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	HC
Anaerostipes	TNF-a	Anaerostipes-Th1 and Th2 cell differentiation+TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	HC
Anaerostipes	TNF-a	Anaerostipes-18:1-LPC+blood+TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	HC
Anaerostipes	TNF-a	Anaerostipes-Th17 cell differentiation+TNF-a	Indirect	Genus	serum_cytokines	0.568	0.613	no	no	no	no	no	no	HC
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	HC
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool+Phenylacetic acid+stool+20:1+blood+TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	HC
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool+Phenylacetic acid+stool+18:1-LPC+blood+TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	HC
Isovaleric acid+stool	TNF-a	Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+TNF-a	Indirect	stool_scfa	serum_cytokines	0.343	0.613	no	no	no	no	no	no	HC
Paraprevotella	TNF-a	Paraprevotella-Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.118	0.613	no	no	no	no	no	no	HC
Paraprevotella	TNF-a	Paraprevotella+Carbon metabolism-TNF-a	Indirect	Genus	serum_cytokines	0.118	0.613	no	no	no	no	no	no	HC
Paraprevotella	TNF-a	Paraprevotella-L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.118	0.613	no	no	no	no	no	no	HC
Paraprevotella	TNF-a	Paraprevotella+Glycolysis / Gluconeogenesis-TNF-a	Indirect	Genus	serum_cytokines	0.118	0.613	no	no	no	no	no	no	HC
¦Ø-MCA+stool	TNF-a	¦Ø-MCA+stool-Acetic acid+stool-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.919	0.613	no	no	no	no	no	no	HC
Phenylacetic acid+stool	TNF-a	Phenylacetic acid+stool+20:1+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.785	0.613	no	no	no	no	no	no	HC
Phenylacetic acid+stool	TNF-a	Phenylacetic acid+stool+18:1-LPC+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.785	0.613	no	no	no	no	no	no	HC
Phenylacetic acid+stool	TNF-a	Phenylacetic acid+stool+20:0+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.785	0.613	no	no	no	no	no	no	HC
Gemmiger	TNF-a	Gemmiger-TNF-a	Direct	Genus	serum_cytokines	0.595	0.613	no	no	no	no	no	no	HC
GDCA+stool	TNF-a	GDCA+stool-TXB2+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.656	0.613	no	no	no	no	no	no	HC
L-Tyrosine+stool	TNF-a	L-Tyrosine+stool+16:0/22:6-PE+blood+18:0/18:0-PS+blood-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.613	no	no	no	no	no	no	HC
L-Tyrosine+stool	TNF-a	L-Tyrosine+stool+20:1-LPA+blood-L-Homocystine+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.613	no	no	no	no	no	no	HC
L-Tyrosine+stool	TNF-a	L-Tyrosine+stool+8-HETE+blood-L-Homocystine+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.613	no	no	no	no	no	no	HC
L-Tyrosine+stool	TNF-a	L-Tyrosine+stool-12-ketoDCA+blood-18:1-LPC+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.613	no	no	no	no	no	no	HC
L-Tyrosine+stool	TNF-a	L-Tyrosine+stool+8-HETE+blood+TXB2+blood-TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.613	no	no	no	no	no	no	HC
L-Tyrosine+stool	TNF-a	L-Tyrosine+stool-18:3n6+blood-Choline+blood+TNF-a	Indirect	stool_cometabolism	serum_cytokines	0.44	0.613	no	no	no	no	no	no	HC
CDCA+stool	TNF-a	CDCA+stool+GCA+stool+16:0/18:0-PS+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.663	0.613	no	no	no	no	no	no	HC
CDCA+stool	TNF-a	CDCA+stool+18:3n3+blood+EPA+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.663	0.613	no	no	no	no	no	no	HC
CDCA+stool	TNF-a	CDCA+stool+nutriCA+stool-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.663	0.613	no	no	no	no	no	no	HC
CDCA+stool	TNF-a	CDCA+stool+HCA+stool-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.663	0.613	no	no	no	no	no	no	HC
CA+stool	TNF-a	CA+stool+GCA+stool+16:0/18:0-PS+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	HC
CA+stool	TNF-a	CA+stool+nutriCA+stool-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	HC
CA+stool	TNF-a	CA+stool+HCA+stool-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	HC
CA+stool	TNF-a	CA+stool+GDCA+stool-TXB2+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.827	0.613	no	no	no	no	no	no	HC
HDCA+blood	TNF-a	HDCA+blood+L-Aspartic acid+blood+TXB2+blood-TNF-a	Indirect	serum_bileacids	serum_cytokines	0.483	0.613	no	no	no	no	no	no	HC
HDCA+blood	TNF-a	HDCA+blood+L-Asparagine+blood+L-Citrulline+blood+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.483	0.613	no	no	no	no	no	no	HC
UDCA+stool	TNF-a	UDCA+stool+18:3n3+blood+EPA+blood-TNF-a	Indirect	stool_bileacids	serum_cytokines	0.266	0.613	no	no	no	no	no	no	HC
nutriCA+stool	TNF-a	nutriCA+stool-L-Homocystine+blood+TNF-a	Indirect	stool_bileacids	serum_cytokines	0.481	0.613	no	no	no	no	no	no	HC
acetic acid C2+blood	TNF-a	acetic acid C2+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+L-Citrulline+blood+TNF-a	Indirect	serum_scfa	serum_cytokines	0.000193	0.613	up	dn	no	no	no	no	HC
acetic acid C2+blood	TNF-a	acetic acid C2+blood+heptanoic acid C7+blood+L-Asparagine+blood+L-Citrulline+blood+TNF-a	Indirect	serum_scfa	serum_cytokines	0.000193	0.613	up	dn	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-Toll-like receptor signaling pathway+B cell receptor signaling pathway+TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-AMPK signaling pathway-B cell receptor signaling pathway+TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-Adrenergic signaling in cardiomyocytes+Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-Toll-like receptor signaling pathway+Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium+14:0/18:2-PC+blood-Choline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium+14:0/18:2-PC+blood+EPA+blood-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium+18:0/22:6-PC+blood+EPA+blood-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium+20:5/18:0-PC+blood+EPA+blood-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-Adipocytokine signaling pathway-EPA+blood-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium+nutriCA+stool-L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-Chemical carcinogenesis - receptor activation+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-Chagas disease+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium+GPC+blood-L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-Adrenergic signaling in cardiomyocytes+L-Homocystine+blood+TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium+18:0/22:6-PC+blood-20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium+Peroxisome-20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-Chagas disease+20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium+18:0/22:6-PC+blood+TXB2+blood-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium+Peroxisome+18:0/18:0-PS+blood-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-Chagas disease-18:0/18:0-PS+blood-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-Adipocytokine signaling pathway-18:0/18:0-PS+blood-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-Adrenergic signaling in cardiomyocytes-18:0/18:0-PS+blood-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium+Peroxisome+Longevity regulating pathway - multiple species-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-AMPK signaling pathway-Longevity regulating pathway - multiple species-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium+Peroxisome+Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-Adipocytokine signaling pathway-Primary immunodeficiency-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-Adipocytokine signaling pathway+L-Citrulline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-Adipocytokine signaling pathway-16:0/18:0-PS+blood-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-Adipocytokine signaling pathway-14:0+blood-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-Adipocytokine signaling pathway+20:1+blood+TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
Clostridium	TNF-a	Clostridium-Adipocytokine signaling pathway-16:0+blood-TNF-a	Indirect	Genus	serum_cytokines	0.925	0.613	no	no	no	no	no	no	HC
12-ketoDCA+blood	TNF-a	12-ketoDCA+blood-18:1-LPC+blood+TNF-a	Indirect	serum_bileacids	serum_cytokines	0.517	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Rap1 signaling pathway-NF-kappa B signaling pathway+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Salivary secretion-Small cell lung cancer+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Focal adhesion-Small cell lung cancer+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Rap1 signaling pathway-Small cell lung cancer+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Leukocyte transendothelial migration-Small cell lung cancer+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Platelet activation-Small cell lung cancer+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Oxytocin signaling pathway-Small cell lung cancer+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-16:0-LPC+blood+TXB2+blood-TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Thyroid hormone signaling pathway-Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Focal adhesion-Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Rap1 signaling pathway-Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Leukocyte transendothelial migration-Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Platelet activation-Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Oxytocin signaling pathway-Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-18:2-LPC+blood+20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Focal adhesion-L-Citrulline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Rap1 signaling pathway-L-Citrulline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Leukocyte transendothelial migration-L-Citrulline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Platelet activation-L-Citrulline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Oxytocin signaling pathway-L-Citrulline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Focal adhesion-Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Platelet activation-Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Butyricicoccus	TNF-a	Butyricicoccus-Oxytocin signaling pathway-Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.852	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Rap1 signaling pathway-NF-kappa B signaling pathway+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Salivary secretion-Small cell lung cancer+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Focal adhesion-Small cell lung cancer+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Rap1 signaling pathway-Small cell lung cancer+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Leukocyte transendothelial migration-Small cell lung cancer+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Platelet activation-Small cell lung cancer+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Oxytocin signaling pathway-Small cell lung cancer+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-16:0-LPC+blood+TXB2+blood-TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Thyroid hormone signaling pathway-Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Focal adhesion-Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Rap1 signaling pathway-Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Leukocyte transendothelial migration-Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Platelet activation-Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Oxytocin signaling pathway-Insulin resistance+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-18:2-LPC+blood+20:0+blood+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Focal adhesion-L-Citrulline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Rap1 signaling pathway-L-Citrulline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Leukocyte transendothelial migration-L-Citrulline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Platelet activation-L-Citrulline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Oxytocin signaling pathway-L-Citrulline+blood+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Focal adhesion-Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Platelet activation-Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Wautersiella	TNF-a	Wautersiella+Butyricicoccus-Oxytocin signaling pathway-Pathways in cancer+TNF-a	Indirect	Genus	serum_cytokines	0.289	0.613	no	no	no	no	no	no	HC
Blautia	MIP-1b	Blautia+Peroxisome-Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	HC
Blautia	MIP-1b	Blautia+Arginine and proline metabolism-Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	HC
Blautia	MIP-1b	Blautia-Chemical carcinogenesis - receptor activation+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	HC
Blautia	MIP-1b	Blautia-Ras signaling pathway+Alcoholism-MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	HC
Blautia	MIP-1b	Blautia-Ras signaling pathway+Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	HC
Blautia	MIP-1b	Blautia+Peroxisome-Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	HC
Blautia	MIP-1b	Blautia+Arginine and proline metabolism-Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	HC
Blautia	MIP-1b	Blautia+16:0/20:5-PC+blood-Betaine+blood-MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	HC
Blautia	MIP-1b	Blautia-Butyric acid+stool-L-Tryptophan+stool+MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	HC
Blautia	MIP-1b	Blautia-Butyric acid+stool-L-Phenylalanine+stool+MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	HC
Blautia	MIP-1b	Blautia+Peroxisome-Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	HC
Blautia	MIP-1b	Blautia+Arginine and proline metabolism-Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	HC
Blautia	MIP-1b	Blautia-Ras signaling pathway+Calcium signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	HC
Blautia	MIP-1b	Blautia+Arginine and proline metabolism-Calcium signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	HC
Blautia	MIP-1b	Blautia-18:1-LPE+blood-Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	HC
Blautia	MIP-1b	Blautia+Peroxisome-Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	HC
Blautia	MIP-1b	Blautia-Cushing syndrome+Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.632	up	dn	dn	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-9-HODE+blood+Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Carbon metabolism-Necroptosis-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-Phosphatidylinositol signaling system+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Biosynthesis of amino acids-L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-RNA degradation+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-Colorectal cancer+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Carbon metabolism-L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Glycolysis / Gluconeogenesis-L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+16:1/18:2-PG+blood+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-Pathways in cancer+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-mRNA surveillance pathway+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Glycolysis / Gluconeogenesis-L-Arginine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-Phosphatidylinositol signaling system+Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Biosynthesis of amino acids-Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-RNA degradation+Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Carbon metabolism-Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Glycolysis / Gluconeogenesis-Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-mRNA surveillance pathway+Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+16:1/18:2-PG+blood+Betaine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-Phosphatidylinositol signaling system+Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Biosynthesis of amino acids-Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-RNA degradation+Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Carbon metabolism-Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Glycolysis / Gluconeogenesis-Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-mRNA surveillance pathway+Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Biosynthesis of amino acids-Calcium signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-RNA degradation+Calcium signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Carbon metabolism-Calcium signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Glycolysis / Gluconeogenesis-Calcium signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-mRNA surveillance pathway+Calcium signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-Phosphatidylinositol signaling system+Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Biosynthesis of amino acids-Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-RNA degradation+Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Carbon metabolism-Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-mRNA surveillance pathway+Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Carbon metabolism-Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-Phosphatidylinositol signaling system+L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Biosynthesis of amino acids-L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-RNA degradation+L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Carbon metabolism-L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Glycolysis / Gluconeogenesis-L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+16:1/18:2-PG+blood+L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-Pathways in cancer+L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-mRNA surveillance pathway+L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Carbon metabolism-Longevity regulating pathway-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Glycolysis / Gluconeogenesis-Longevity regulating pathway-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-Phosphatidylinositol signaling system+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Biosynthesis of amino acids-L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-RNA degradation+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-Colorectal cancer+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Carbon metabolism-L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Glycolysis / Gluconeogenesis-L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-Pathways in cancer+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides-mRNA surveillance pathway+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Parabacteroides	MIP-1b	Parabacteroides+Carbon metabolism-L-Tryptophan+blood-MIP-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.632	no	up	up	no	no	no	HC
Dorea	MIP-1b	Dorea-Endocrine resistance+Calcium signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-GnRH signaling pathway+Alcoholism-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-GnRH signaling pathway-20:4/18:0-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-Endocrine resistance+Glutamatergic synapse-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-Endocrine resistance+Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-GnRH signaling pathway+Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-Endocrine resistance+L-Tryptophan+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea+16:0/18:3-PC+blood-L-Tryptophan+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-Fc epsilon RI signaling pathway+L-Tryptophan+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	"Dorea-Growth hormone synthesis, secretion and action+L-Tryptophan+blood-MIP-1b"	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-Endocrine resistance+Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-GnRH signaling pathway+Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-Endocrine resistance+Longevity regulating pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-Endocrine resistance+Necroptosis-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-VEGF signaling pathway+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea+Legionellosis-L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-Fc epsilon RI signaling pathway+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	"Dorea-Growth hormone synthesis, secretion and action+L-Methionine+blood-MIP-1b"	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-VEGF signaling pathway+L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-Fc epsilon RI signaling pathway+L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-VEGF signaling pathway+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-Endocrine resistance+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-Chemical carcinogenesis - receptor activation+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-Fc epsilon RI signaling pathway+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	"Dorea-Growth hormone synthesis, secretion and action+L-Phenylalanine+blood-MIP-1b"	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-Endocrine resistance+Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea+Legionellosis-L-Phenylalanine+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea+Legionellosis-L-Arginine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea+16:0/18:3-PC+blood+d18:1-20:0-SM+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	"Dorea-Growth hormone synthesis, secretion and action-d18:1-20:0-SM+blood+MIP-1b"	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea+Legionellosis-TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-Endocrine resistance+Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Dorea	MIP-1b	Dorea-GnRH signaling pathway+Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.00362	0.632	up	no	dn	no	no	no	HC
Faecalibacterium	MIP-1b	Faecalibacterium-MIP-1b	Direct	Genus	serum_cytokines	0.0039	0.632	no	dn	dn	no	no	no	HC
TUDCA+blood	MIP-1b	TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13-IL-2-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.0282	0.632	no	no	dn	no	no	no	HC
TUDCA+blood	MIP-1b	TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.0282	0.632	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	MIP-1b	isocapric acid iso-C6+blood+L-Tyrosine+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.0458	0.632	no	no	dn	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Ribosome+Calcium signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides+Biosynthesis of amino acids-Calcium signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides+AGE-RAGE signaling pathway in diabetic complications+L-Tryptophan+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Ribosome-L-Tryptophan+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Coronavirus disease - COVID-19-L-Tryptophan+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-cAMP signaling pathway+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-L-Homocystine+blood+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides+AGE-RAGE signaling pathway in diabetic complications+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides+Biosynthesis of amino acids-L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides+UDCA+stool-TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-cAMP signaling pathway+Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Mitophagy - animal+Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Ribosome+Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Thermogenesis+Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Mitophagy - animal-16:0/22:6-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Ribosome-16:0/22:6-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Shigellosis-16:0/22:6-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Coronavirus disease - COVID-19-16:0/22:6-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Mitophagy - animal-20:4/18:0-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Shigellosis-20:4/18:0-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-cAMP signaling pathway+L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides+Biosynthesis of amino acids-L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Mitophagy - animal+Ferroptosis-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Mitophagy - animal+Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Serotonergic synapse+Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Ribosome+Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides+Biosynthesis of amino acids-Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Thermogenesis+Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides+nutriCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Mitophagy - animal-d18:1-20:0-SM+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Mitophagy - animal+Longevity regulating pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Mitophagy - animal+Malaria-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Shigellosis+Malaria-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-cAMP signaling pathway+Alcoholism-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Mitophagy - animal+Necroptosis-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Ribosome+Necroptosis-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-cAMP signaling pathway+Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Mitophagy - animal+Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Ribosome+Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides+Biosynthesis of amino acids-Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-cAMP signaling pathway+Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Mitophagy - animal+Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Ribosome+Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides+Biosynthesis of amino acids-Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-Thermogenesis+Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides-cAMP signaling pathway+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides+AGE-RAGE signaling pathway in diabetic complications+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Bacteroides	MIP-1b	Bacteroides+Biosynthesis of amino acids-L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.000267	0.632	dn	dn	up	no	no	no	HC
Propionic acid+stool	MIP-1b	Propionic acid+stool-d18:1-22:1-SM+blood-L-Phenylalanine+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.632	dn	no	up	no	no	no	HC
[Ruminococcus]	MIP-1b	[Ruminococcus]+MIP-1b	Direct	Genus	serum_cytokines	0.0679	0.632	no	no	dn	no	no	no	HC
GUDCA+blood	MIP-1b	GUDCA+blood-PUFA%+blood+TMAO+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.632	no	no	dn	no	no	no	HC
GUDCA+blood	MIP-1b	GUDCA+blood-PUFA/UFA+blood+TMAO+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.632	no	no	dn	no	no	no	HC
Acetic acid+stool	MIP-1b	Acetic acid+stool+Butyric acid+stool-L-Tryptophan+stool+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.0656	0.632	dn	no	no	no	no	no	HC
Acetic acid+stool	MIP-1b	Acetic acid+stool+Butyric acid+stool-L-Phenylalanine+stool+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.0656	0.632	dn	no	no	no	no	no	HC
Acetic acid+stool	MIP-1b	Acetic acid+stool-L-Homocystine+blood+L-Methionine+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.0656	0.632	dn	no	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-MAPK signaling pathway+16:0/22:6-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-Olfactory transduction+16:0/22:6-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-MAPK signaling pathway-Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-Peroxisome-Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-NOD-like receptor signaling pathway-Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes+16:0/18:2-PC+blood+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-cGMP-PKG signaling pathway+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-Peroxisome-Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-NOD-like receptor signaling pathway-Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-Peroxisome-Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-Peroxisome-Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-NOD-like receptor signaling pathway-Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes+L-Glutamine+blood-IL-9+MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-Progesterone-mediated oocyte maturation-Malaria-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-MAPK signaling pathway-Malaria-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-Progesterone-mediated oocyte maturation+L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-Hepatitis B+L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-cGMP-PKG signaling pathway+L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-GDCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-FoxO signaling pathway+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-Hepatitis B+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes+16:0/18:2-PC+blood+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes+18:1/16:0-PC+blood+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes+16:0/20:4-PC+blood+Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-9-HODE+blood+Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-4-hydroxybenzoic acid+stool+Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-Primary immunodeficiency-L-Arginine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-Primary immunodeficiency+20:4/18:0-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-MAPK signaling pathway+20:4/18:0-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-Olfactory transduction+20:4/18:0-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes-Primary immunodeficiency+18:1/18:1-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes+16:0/20:4-PC+blood-18:1/18:1-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes+16:0/18:2-PC+blood-18:1/18:1-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes+18:1/16:0-PC+blood-18:1/18:1-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes+20:3/16:0-PC+blood+TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes+16:0/20:4-PC+blood+TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Alistipes	MIP-1b	Alistipes+L-Glutamine+blood+TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.0114	0.632	no	up	no	no	no	no	HC
Butyricimonas	MIP-1b	Butyricimonas+Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	0.17	0.632	no	no	no	no	no	no	HC
Butyricimonas	MIP-1b	Butyricimonas+L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.17	0.632	no	no	no	no	no	no	HC
Butyricimonas	MIP-1b	Butyricimonas+Calcium signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.17	0.632	no	no	no	no	no	no	HC
Butyricimonas	MIP-1b	Butyricimonas+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.17	0.632	no	no	no	no	no	no	HC
Butyricimonas	MIP-1b	Butyricimonas+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.17	0.632	no	no	no	no	no	no	HC
Collinsella	MIP-1b	Collinsella-TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.128	0.632	no	no	no	no	no	no	HC
iso-DCA+stool	MIP-1b	iso-DCA+stool-L-Tryptophan+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.632	no	no	no	no	no	no	HC
LCA+stool	MIP-1b	LCA+stool-TCA+stool-L-Tryptophan+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.632	no	no	no	no	no	no	HC
LCA+stool	MIP-1b	LCA+stool+16:0/18:2-PC+blood-18:1/18:1-PE+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.632	no	no	no	no	no	no	HC
LCA+stool	MIP-1b	LCA+stool+18:1/16:0-PC+blood-18:1/18:1-PE+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.632	no	no	no	no	no	no	HC
LCA+stool	MIP-1b	"LCA+stool+9,10-EPOME+blood-Betaine+blood-MIP-1b"	Indirect	stool_bileacids	serum_cytokines	0.314	0.632	no	no	no	no	no	no	HC
LCA+stool	MIP-1b	LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.632	no	no	no	no	no	no	HC
LCA+stool	MIP-1b	LCA+stool-DMG+blood+L-Arginine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.632	no	no	no	no	no	no	HC
LCA+stool	MIP-1b	LCA+stool+16:0/18:2-PC+blood+L-Methionine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.632	no	no	no	no	no	no	HC
LCA+stool	MIP-1b	LCA+stool+16:0/18:2-PC+blood+L-Phenylalanine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.632	no	no	no	no	no	no	HC
LCA+stool	MIP-1b	LCA+stool+18:1/16:0-PC+blood+L-Phenylalanine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.632	no	no	no	no	no	no	HC
Akkermansia	MIP-1b	Akkermansia+d18:1-22:1-SM+blood-L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	HC
Akkermansia	MIP-1b	Akkermansia-Wnt signaling pathway+Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	HC
Akkermansia	MIP-1b	Akkermansia-Ribosome+Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	HC
Akkermansia	MIP-1b	Akkermansia-Ribosome+Calcium signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	HC
Akkermansia	MIP-1b	Akkermansia-Ribosome+Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	HC
Akkermansia	MIP-1b	Akkermansia-Ribosome+Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	HC
Akkermansia	MIP-1b	Akkermansia-Ribosome+Necroptosis-MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	HC
Akkermansia	MIP-1b	Akkermansia+Pertussis+d18:1-20:0-SM+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	HC
Akkermansia	MIP-1b	Akkermansia-Coronavirus disease - COVID-19-16:0/22:6-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	HC
Akkermansia	MIP-1b	Akkermansia-Ribosome-16:0/22:6-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	HC
Akkermansia	MIP-1b	Akkermansia+TLCA+stool+IL-9+MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	HC
Akkermansia	MIP-1b	Akkermansia-Coronavirus disease - COVID-19-L-Tryptophan+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	HC
Akkermansia	MIP-1b	Akkermansia-Ribosome-L-Tryptophan+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	HC
Akkermansia	MIP-1b	Akkermansia-Ribosome+Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	0.23	0.632	no	no	no	no	no	no	HC
Bifidobacterium	MIP-1b	Bifidobacterium-18:1-LPE+blood-Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.105	0.632	no	dn	no	no	no	no	HC
Bifidobacterium	MIP-1b	Bifidobacterium-L-Ornithine+blood-IL-9+MIP-1b	Indirect	Genus	serum_cytokines	0.105	0.632	no	dn	no	no	no	no	HC
Bifidobacterium	MIP-1b	Bifidobacterium-Intestinal immune network for IgA production-16:0/22:6-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.105	0.632	no	dn	no	no	no	no	HC
Bifidobacterium	MIP-1b	Bifidobacterium+20:4-LPC+blood+TMAO+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.105	0.632	no	dn	no	no	no	no	HC
Bifidobacterium	MIP-1b	Bifidobacterium+20:4-LPC+blood+L-Tryptophan+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.105	0.632	no	dn	no	no	no	no	HC
Bifidobacterium	MIP-1b	Bifidobacterium-Intestinal immune network for IgA production-20:4/18:0-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.105	0.632	no	dn	no	no	no	no	HC
Bifidobacterium	MIP-1b	Bifidobacterium-Intestinal immune network for IgA production-18:1/18:1-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.105	0.632	no	dn	no	no	no	no	HC
Bifidobacterium	MIP-1b	Bifidobacterium+d18:1-14:0-SM+blood+d18:1-20:0-SM+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.105	0.632	no	dn	no	no	no	no	HC
Bifidobacterium	MIP-1b	Bifidobacterium+24:0+blood+d18:1-20:0-SM+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.105	0.632	no	dn	no	no	no	no	HC
Bifidobacterium	MIP-1b	Bifidobacterium+d18:1-14:0-SM+blood-L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.105	0.632	no	dn	no	no	no	no	HC
Bifidobacterium	MIP-1b	Bifidobacterium+13-HODE+blood+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.105	0.632	no	dn	no	no	no	no	HC
Bifidobacterium	MIP-1b	Bifidobacterium-Intestinal immune network for IgA production+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.105	0.632	no	dn	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Ubiquitin mediated proteolysis-d18:1-20:0-SM+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Olfactory transduction+16:0/22:6-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Coronavirus disease - COVID-19-16:0/22:6-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Osteoclast differentiation+16:0/22:6-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Ribosome-16:0/22:6-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Fc gamma R-mediated phagocytosis+16:0/22:6-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Ubiquitin mediated proteolysis+Ferroptosis-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Ubiquitin mediated proteolysis+Necroptosis-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Endocrine resistance+Necroptosis-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Ribosome+Necroptosis-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Ubiquitin mediated proteolysis+Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Thyroid hormone synthesis+Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Thermogenesis+Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Endocrine resistance+Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-NOD-like receptor signaling pathway-Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Dopaminergic synapse+Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Osteoclast differentiation-Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Ribosome+Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Peroxisome-Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Fc gamma R-mediated phagocytosis-Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-4-hydroxybenzoic acid+stool+Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Dopaminergic synapse+Alcoholism-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Neutrophil extracellular trap formation+L-Tyrosine+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Neutrophil extracellular trap formation+L-Tryptophan+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Coronavirus disease - COVID-19-L-Tryptophan+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Ribosome-L-Tryptophan+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Neutrophil extracellular trap formation+L-Phenylalanine+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Ubiquitin mediated proteolysis+Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Thyroid hormone synthesis+Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Thermogenesis+Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Endocrine resistance+Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-IL-17 signaling pathway-Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-NOD-like receptor signaling pathway-Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Lysosome-Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Dopaminergic synapse+Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Neutrophil extracellular trap formation-Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Osteoclast differentiation-Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Ribosome+Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Biosynthesis of amino acids-Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Peroxisome-Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Fc gamma R-mediated phagocytosis-Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Olfactory transduction+20:4/18:0-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Thyroid hormone synthesis-20:4/18:0-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+18:1/18:1-PC+blood-20:4/18:0-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Fc gamma R-mediated phagocytosis+20:4/18:0-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Ubiquitin mediated proteolysis+Longevity regulating pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Endocrine resistance+Longevity regulating pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Thyroid hormone synthesis+Malaria-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-cGMP-PKG signaling pathway+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Dopaminergic synapse+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Pancreatic cancer+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Biosynthesis of amino acids-L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-cGMP-PKG signaling pathway+L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Biosynthesis of amino acids-L-Tyrosine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+18:1/18:1-PC+blood-18:1/18:1-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Endocrine resistance+L-Tryptophan+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-TCA+stool-L-Tryptophan+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Ubiquitin mediated proteolysis+Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Thyroid hormone synthesis+Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Thermogenesis+Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Endocrine resistance+Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-NOD-like receptor signaling pathway-Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Dopaminergic synapse+Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Neutrophil extracellular trap formation-Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Osteoclast differentiation-Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Ribosome+Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Biosynthesis of amino acids-Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Peroxisome-Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Fc gamma R-mediated phagocytosis-Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Ubiquitin mediated proteolysis+Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Endocrine resistance+Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Ribosome+Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Biosynthesis of amino acids-Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Peroxisome-Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Endocrine resistance+Calcium signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Ribosome+Calcium signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Biosynthesis of amino acids-Calcium signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Endocrine resistance+Glutamatergic synapse-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus+Endocrine resistance+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Pancreatic cancer+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-Biosynthesis of amino acids-L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
Ruminococcus	MIP-1b	Ruminococcus-FoxO signaling pathway+L-Phenylalanine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.335	0.632	no	no	no	no	no	no	HC
GCDCA+blood	MIP-1b	GCDCA+blood-PUFA%+blood+TMAO+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.632	no	no	no	no	no	no	HC
GCDCA+blood	MIP-1b	GCDCA+blood+L-Alanine+blood-IL-9+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.632	no	no	no	no	no	no	HC
[Prevotella]	MIP-1b	[Prevotella]-Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.367	0.632	no	no	no	no	no	no	HC
[Prevotella]	MIP-1b	[Prevotella]-Glutamatergic synapse-MIP-1b	Indirect	Genus	serum_cytokines	0.367	0.632	no	no	no	no	no	no	HC
ACA+blood	MIP-1b	ACA+blood-d18:1-14:0-SM+blood-L-Methionine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.338	0.632	no	no	no	no	no	no	HC
ACA+blood	MIP-1b	ACA+blood-d18:1-14:0-SM+blood+d18:1-20:0-SM+blood+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.338	0.632	no	no	no	no	no	no	HC
DCA+stool	MIP-1b	DCA+stool-L-Tyrosine+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.632	no	no	no	no	no	no	HC
DCA+stool	MIP-1b	DCA+stool-L-Phenylalanine+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.632	no	no	no	no	no	no	HC
DCA+stool	MIP-1b	DCA+stool-L-Tryptophan+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.632	no	no	no	no	no	no	HC
2-hydroxyhippuric acid+urine	MIP-1b	2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2-MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.215	0.632	no	no	no	no	no	no	HC
Butyric acid+stool	MIP-1b	Butyric acid+stool-L-Tryptophan+stool+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.632	dn	no	no	no	no	no	HC
Butyric acid+stool	MIP-1b	Butyric acid+stool-L-Phenylalanine+stool+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.632	dn	no	no	no	no	no	HC
4-hydroxybenzoic acid+stool	MIP-1b	4-hydroxybenzoic acid+stool+Cysteine+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.632	no	dn	no	no	no	no	HC
GCA+blood	MIP-1b	GCA+blood+L-Alanine+blood-IL-9+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.16	0.632	no	no	no	no	no	no	HC
ACA+stool	MIP-1b	ACA+stool-18:0/18:2-PI+blood+18:1/18:1-PE+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.417	0.632	no	no	no	no	no	no	HC
ACA+stool	MIP-1b	ACA+stool-18:0/18:2-PI+blood+20:4/18:0-PE+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.417	0.632	no	no	no	no	no	no	HC
CDCA+blood	MIP-1b	CDCA+blood-L-2-Aminobutyric acid+blood+L-Tyrosine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.632	no	no	no	no	no	no	HC
CDCA+blood	MIP-1b	CDCA+blood-Creatinine+blood+L-Tyrosine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.632	no	no	no	no	no	no	HC
CDCA+blood	MIP-1b	CDCA+blood-Creatinine+blood+Cysteine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.632	no	no	no	no	no	no	HC
CDCA+blood	MIP-1b	CDCA+blood-Creatinine+blood+L-Phenylalanine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.632	no	no	no	no	no	no	HC
CDCA+blood	MIP-1b	CDCA+blood-Creatinine+blood+L-Tryptophan+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.632	no	no	no	no	no	no	HC
CDCA+blood	MIP-1b	CDCA+blood-L-2-Aminobutyric acid+blood+L-Arginine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.632	no	no	no	no	no	no	HC
CDCA+blood	MIP-1b	CDCA+blood-Creatinine+blood+L-Arginine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.632	no	no	no	no	no	no	HC
CDCA+blood	MIP-1b	CDCA+blood-L-2-Aminobutyric acid+blood+L-Methionine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.632	no	no	no	no	no	no	HC
CDCA+blood	MIP-1b	CDCA+blood-Creatinine+blood+L-Methionine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.632	no	no	no	no	no	no	HC
CDCA+blood	MIP-1b	CDCA+blood-d18:1-18:0-SM+blood+d18:1-20:0-SM+blood+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.632	no	no	no	no	no	no	HC
CDCA+blood	MIP-1b	CDCA+blood-d18:1-18:1-SM+blood+d18:1-20:0-SM+blood+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.632	no	no	no	no	no	no	HC
capric acid C6+blood	MIP-1b	capric acid C6+blood-Cystine+blood+L-Arginine+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.433	0.632	no	no	no	no	no	no	HC
capric acid C6+blood	MIP-1b	capric acid C6+blood-Cystine+blood-IL-9+MIP-1b	Indirect	serum_scfa	serum_cytokines	0.433	0.632	no	no	no	no	no	no	HC
Prevotella	MIP-1b	Prevotella-L-Tryptophan+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.287	0.632	no	no	no	no	no	no	HC
TCA+blood	MIP-1b	"TCA+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-9+MIP-1b"	Indirect	serum_bileacids	serum_cytokines	0.339	0.632	no	no	no	no	no	no	HC
iso-DCA+blood	MIP-1b	iso-DCA+blood+L-Histidine+blood+L-Tyrosine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.38	0.632	no	no	no	no	no	no	HC
iso-DCA+blood	MIP-1b	iso-DCA+blood+PUFA/UFA+blood+TMAO+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.38	0.632	no	no	no	no	no	no	HC
iso-DCA+blood	MIP-1b	iso-DCA+blood+n6/n3+blood+TMAO+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.38	0.632	no	no	no	no	no	no	HC
iso-DCA+blood	MIP-1b	iso-DCA+blood+PUFA%+blood+TMAO+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.38	0.632	no	no	no	no	no	no	HC
iso-DCA+blood	MIP-1b	iso-DCA+blood+L-Histidine+blood+L-Methionine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.38	0.632	no	no	no	no	no	no	HC
iso-DCA+blood	MIP-1b	iso-DCA+blood+L-Histidine+blood+L-Phenylalanine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.38	0.632	no	no	no	no	no	no	HC
iso-DCA+blood	MIP-1b	iso-DCA+blood+L-Histidine+blood+L-Tryptophan+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.38	0.632	no	no	no	no	no	no	HC
HCA+stool	MIP-1b	HCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.632	no	no	no	no	no	no	HC
Roseburia	MIP-1b	Roseburia+Malaria-MIP-1b	Indirect	Genus	serum_cytokines	0.495	0.632	no	no	no	no	no	no	HC
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool-Cystine+blood-IL-9+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	HC
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool-Cystine+blood+L-Arginine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	HC
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool+DCA+stool-L-Tryptophan+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	HC
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool+DCA+stool-L-Phenylalanine+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	HC
12-ketoDCA+stool	MIP-1b	12-ketoDCA+stool+DCA+stool-L-Tyrosine+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.632	no	no	no	no	no	no	HC
GLCA+blood	MIP-1b	GLCA+blood+L-Glutamine+blood+TMAO+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.319	0.632	no	no	no	no	no	no	HC
GLCA+blood	MIP-1b	GLCA+blood+L-Glutamine+blood-IL-9+MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.319	0.632	no	no	no	no	no	no	HC
L-Tryptophan+stool	MIP-1b	L-Tryptophan+stool+MIP-1b	Direct	stool_cometabolism	serum_cytokines	0.557	0.632	no	no	no	no	no	no	HC
CA+blood	MIP-1b	CA+blood-isocapric acid iso-C6+blood+L-Tyrosine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.606	0.632	no	no	no	no	no	no	HC
CA+blood	MIP-1b	CA+blood-L-Isoleucine+blood+L-Phenylalanine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.606	0.632	no	no	no	no	no	no	HC
CA+blood	MIP-1b	CA+blood-L-Isoleucine+blood+L-Tryptophan+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.606	0.632	no	no	no	no	no	no	HC
GUDCA+stool	MIP-1b	GUDCA+stool+L-Tryptophan+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0085	0.632	no	dn	no	no	no	no	HC
L-Phenylalanine+stool	MIP-1b	L-Phenylalanine+stool+MIP-1b	Direct	stool_cometabolism	serum_cytokines	0.398	0.632	no	no	no	no	no	no	HC
butyric acid C4+blood	MIP-1b	butyric acid C4+blood+Cystine+blood-IL-9+MIP-1b	Indirect	serum_scfa	serum_cytokines	0.407	0.632	no	no	no	no	no	no	HC
butyric acid C4+blood	MIP-1b	butyric acid C4+blood+Cystine+blood+L-Arginine+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.407	0.632	no	no	no	no	no	no	HC
butyric acid C4+blood	MIP-1b	butyric acid C4+blood+iso-heptanoic acid C7+blood-L-Tyrosine+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.407	0.632	no	no	no	no	no	no	HC
butyric acid C4+blood	MIP-1b	butyric acid C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.407	0.632	no	no	no	no	no	no	HC
butyric acid C4+blood	MIP-1b	butyric acid C4+blood+iso-heptanoic acid C7+blood-L-Phenylalanine+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.407	0.632	no	no	no	no	no	no	HC
GCA+stool	MIP-1b	GCA+stool-L-Methionine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.632	no	no	no	no	no	no	HC
GCA+stool	MIP-1b	GCA+stool+16:0/22:6-PE+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.632	no	no	no	no	no	no	HC
Coprococcus	MIP-1b	Coprococcus-Betaine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.612	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira-Salmonella infection+20:4/18:0-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira-Ras signaling pathway+Alcoholism-MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira-Antigen processing and presentation+Alcoholism-MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira-Human T-cell leukemia virus 1 infection-L-Tryptophan+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira-Salmonella infection+d18:1-20:0-SM+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira-nutriCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira-HCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira-Human T-cell leukemia virus 1 infection+d18:1-20:0-SM+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira-Antigen processing and presentation+d18:1-20:0-SM+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira-Antigen processing and presentation-Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira+L-Homocystine+blood+L-Methionine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira-Salmonella infection+16:0/22:6-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira-9-HODE+blood+Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira-20:1-LPA+blood+Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira-4-hydroxybenzoic acid+stool+Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira+DCA+stool-L-Tyrosine+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira-Ras signaling pathway+Calcium signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira+DCA+stool-L-Phenylalanine+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira+DCA+stool-L-Tryptophan+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira+20:5n3+blood-Betaine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
Oscillospira	MIP-1b	Oscillospira-Ras signaling pathway+Adrenergic signaling in cardiomyocytes-MIP-1b	Indirect	Genus	serum_cytokines	0.62	0.632	no	no	no	no	no	no	HC
HCA+blood	MIP-1b	HCA+blood-L-2-Aminobutyric acid+blood+L-Tyrosine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.544	0.632	no	no	no	no	no	no	HC
HCA+blood	MIP-1b	HCA+blood-isocapric acid iso-C6+blood+L-Tyrosine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.544	0.632	no	no	no	no	no	no	HC
HCA+blood	MIP-1b	HCA+blood-L-2-Aminobutyric acid+blood+L-Arginine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.544	0.632	no	no	no	no	no	no	HC
HCA+blood	MIP-1b	HCA+blood-L-2-Aminobutyric acid+blood+L-Methionine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.544	0.632	no	no	no	no	no	no	HC
HCA+blood	MIP-1b	HCA+blood-L-Isoleucine+blood+L-Phenylalanine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.544	0.632	no	no	no	no	no	no	HC
HCA+blood	MIP-1b	HCA+blood-L-Isoleucine+blood+L-Tryptophan+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.544	0.632	no	no	no	no	no	no	HC
iso-LCA+stool	MIP-1b	iso-LCA+stool-16:0/18:3-PC+blood+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.632	no	no	no	no	no	no	HC
iso-LCA+stool	MIP-1b	iso-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.632	no	no	no	no	no	no	HC
iso-LCA+stool	MIP-1b	iso-LCA+stool-16:0/18:3-PC+blood-L-Tryptophan+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.632	no	no	no	no	no	no	HC
iso-LCA+stool	MIP-1b	iso-LCA+stool-UDCA+stool-TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.632	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	MIP-1b	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+TMAO+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.632	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	MIP-1b	2-methyl-butyric acid m-C4+blood+iso-heptanoic acid C7+blood-L-Tyrosine+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.632	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	MIP-1b	2-methyl-butyric acid m-C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.632	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	MIP-1b	2-methyl-butyric acid m-C4+blood+decanoic acid C10+blood+L-Methionine+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.632	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	MIP-1b	2-methyl-butyric acid m-C4+blood+iso-heptanoic acid C7+blood-L-Phenylalanine+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.632	no	no	no	no	no	no	HC
DCA+blood	MIP-1b	DCA+blood-isobutyric acid C4+blood+L-Isoleucine+blood+L-Tryptophan+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.632	no	no	no	no	no	no	HC
DCA+blood	MIP-1b	DCA+blood-isobutyric acid C4+blood+L-Isoleucine+blood+L-Phenylalanine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.632	no	no	no	no	no	no	HC
DCA+blood	MIP-1b	DCA+blood+GUDCA+blood-PUFA%+blood+TMAO+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.632	no	no	no	no	no	no	HC
DCA+blood	MIP-1b	DCA+blood+GUDCA+blood-PUFA/UFA+blood+TMAO+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.632	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/22:6-PC+blood+L-Phenylalanine+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-L-Ornithine+blood-IL-9+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool-Glycine+blood+TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool+14:0/18:2-PC+blood-TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool+14:0+blood-TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	MIP-1b	3-(3-Hydroxyphenyl)propanoic acid+stool+14:0/18:2-PC+blood-Betaine+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.632	no	no	no	no	no	no	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	MIP-1b	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-9+MIP-1b"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.632	up	up	no	no	no	no	HC
GLCA+stool	MIP-1b	GLCA+stool-iso-LCA+stool-UDCA+stool-TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.632	no	no	no	no	no	no	HC
GLCA+stool	MIP-1b	"GLCA+stool-LCA+stool+9,10-EPOME+blood-Betaine+blood-MIP-1b"	Indirect	stool_bileacids	serum_cytokines	0.617	0.632	no	no	no	no	no	no	HC
GLCA+stool	MIP-1b	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-18:1/18:1-PE+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.632	no	no	no	no	no	no	HC
GLCA+stool	MIP-1b	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:1/18:1-PE+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.632	no	no	no	no	no	no	HC
GLCA+stool	MIP-1b	GLCA+stool-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.632	no	no	no	no	no	no	HC
GLCA+stool	MIP-1b	GLCA+stool-iso-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.632	no	no	no	no	no	no	HC
GLCA+stool	MIP-1b	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.632	no	no	no	no	no	no	HC
GLCA+stool	MIP-1b	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+L-Phenylalanine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.632	no	no	no	no	no	no	HC
GLCA+stool	MIP-1b	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Phenylalanine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.632	no	no	no	no	no	no	HC
GLCA+stool	MIP-1b	GLCA+stool-LCA+stool-DMG+blood+L-Arginine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.632	no	no	no	no	no	no	HC
GLCA+stool	MIP-1b	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood-L-Tryptophan+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.632	no	no	no	no	no	no	HC
GLCA+stool	MIP-1b	GLCA+stool-LCA+stool-TCA+stool-L-Tryptophan+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.632	no	no	no	no	no	no	HC
GLCA+stool	MIP-1b	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Methionine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.632	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	MIP-1b	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.632	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	MIP-1b	Indole-3-Acetic acid+stool+L-Tryptophan+stool+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.632	no	no	no	no	no	no	HC
TCA+stool	MIP-1b	TCA+stool-L-Tryptophan+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.632	no	no	no	no	no	no	HC
HDCA+stool	MIP-1b	HDCA+stool+16:0/20:4-PC+blood+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.632	no	no	no	no	no	no	HC
HDCA+stool	MIP-1b	HDCA+stool+20:3/16:0-PC+blood+TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.632	no	no	no	no	no	no	HC
HDCA+stool	MIP-1b	HDCA+stool+16:0/20:4-PC+blood-18:1/18:1-PE+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.632	no	no	no	no	no	no	HC
HDCA+stool	MIP-1b	HDCA+stool+16:0/20:4-PC+blood+Cysteine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.632	no	no	no	no	no	no	HC
HDCA+stool	MIP-1b	HDCA+stool+iso-DCA+stool-L-Tryptophan+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.632	no	no	no	no	no	no	HC
HDCA+stool	MIP-1b	HDCA+stool-16:0/18:3-PC+blood+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.632	no	no	no	no	no	no	HC
HDCA+stool	MIP-1b	HDCA+stool-nutriCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.632	no	no	no	no	no	no	HC
HDCA+stool	MIP-1b	HDCA+stool-16:0/18:3-PC+blood-L-Tryptophan+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.632	no	no	no	no	no	no	HC
Lachnospira	MIP-1b	Lachnospira+16:0/22:6-PE+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.279	0.632	no	no	no	no	no	no	HC
isobutyric acid C4+blood	MIP-1b	isobutyric acid C4+blood+L-Isoleucine+blood+L-Phenylalanine+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.0151	0.632	up	up	no	no	no	no	HC
isobutyric acid C4+blood	MIP-1b	isobutyric acid C4+blood+L-Isoleucine+blood+L-Tryptophan+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.0151	0.632	up	up	no	no	no	no	HC
GCDCA+stool	MIP-1b	GCDCA+stool-L-Tyrosine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.632	no	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	MIP-1b	5-Hydroxytryptamine+stool+GCA+stool+16:0/22:6-PE+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.632	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	MIP-1b	5-Hydroxytryptamine+stool+GCA+stool-L-Methionine+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.632	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	MIP-1b	5-Hydroxytryptamine+stool+GCDCA+stool-L-Tyrosine+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.632	dn	dn	no	no	no	no	HC
Odoribacter	MIP-1b	Odoribacter-Aldosterone synthesis and secretion-MIP-1b	Indirect	Genus	serum_cytokines	0.798	0.632	no	no	no	no	no	no	HC
Isobutyric acid+stool	MIP-1b	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Betaine+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.632	no	no	no	no	no	no	HC
Isobutyric acid+stool	MIP-1b	Isobutyric acid+stool+Isovaleric acid+stool-nutriCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.632	no	no	no	no	no	no	HC
Isobutyric acid+stool	MIP-1b	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-TMAO+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.632	no	no	no	no	no	no	HC
Isobutyric acid+stool	MIP-1b	Isobutyric acid+stool+Phenylacetic acid+stool-22:6n3+blood-TMAO+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.632	no	no	no	no	no	no	HC
Isobutyric acid+stool	MIP-1b	Isobutyric acid+stool+Phenylacetic acid+stool+n6/n3+blood+TMAO+blood-MIP-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.632	no	no	no	no	no	no	HC
Kynurenic acid+stool	MIP-1b	Kynurenic acid+stool-nutriCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.632	dn	dn	no	no	no	no	HC
Kynurenic acid+stool	MIP-1b	Kynurenic acid+stool-UDCA+stool-TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.632	dn	dn	no	no	no	no	HC
L-Tryptophan+urine	MIP-1b	L-Tryptophan+urine+FGF basic-IL-13-IL-2-MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.226	0.632	no	no	no	no	no	no	HC
Eggerthella	MIP-1b	Eggerthella+Clostridium+MIP-1b	Indirect	Genus	serum_cytokines	0.912	0.632	no	no	no	no	no	no	HC
Eggerthella	MIP-1b	Eggerthella-Faecalibacterium-MIP-1b	Indirect	Genus	serum_cytokines	0.912	0.632	no	no	no	no	no	no	HC
Anaerotruncus	MIP-1b	Anaerotruncus-Gemmiger-L-Phenylalanine+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.904	0.632	no	no	no	no	no	no	HC
Anaerotruncus	MIP-1b	Anaerotruncus-Gemmiger-L-Tyrosine+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.904	0.632	no	no	no	no	no	no	HC
Anaerotruncus	MIP-1b	Anaerotruncus-Gemmiger-Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.904	0.632	no	no	no	no	no	no	HC
Anaerotruncus	MIP-1b	Anaerotruncus-Gemmiger-L-Tryptophan+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.904	0.632	no	no	no	no	no	no	HC
Anaerostipes	MIP-1b	Anaerostipes-Th1 and Th2 cell differentiation-Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	HC
Anaerostipes	MIP-1b	Anaerostipes-Th17 cell differentiation-Glucagon signaling pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	HC
Anaerostipes	MIP-1b	Anaerostipes+Human cytomegalovirus infection+d18:1-20:0-SM+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	HC
Anaerostipes	MIP-1b	Anaerostipes+Human T-cell leukemia virus 1 infection+d18:1-20:0-SM+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	HC
Anaerostipes	MIP-1b	Anaerostipes+TCA+stool-L-Tryptophan+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	HC
Anaerostipes	MIP-1b	Anaerostipes+Human T-cell leukemia virus 1 infection-L-Tryptophan+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	HC
Anaerostipes	MIP-1b	Anaerostipes-Inflammatory bowel disease+L-Arginine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	HC
Anaerostipes	MIP-1b	Anaerostipes-Th1 and Th2 cell differentiation+L-Arginine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	HC
Anaerostipes	MIP-1b	Anaerostipes-Th17 cell differentiation+L-Arginine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.568	0.632	no	no	no	no	no	no	HC
Isovaleric acid+stool	MIP-1b	Isovaleric acid+stool-nutriCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.632	no	no	no	no	no	no	HC
Paraprevotella	MIP-1b	Paraprevotella-Longevity regulating pathway-MIP-1b	Indirect	Genus	serum_cytokines	0.118	0.632	no	no	no	no	no	no	HC
Paraprevotella	MIP-1b	Paraprevotella+d18:1-20:0-SM+blood+MIP-1b	Indirect	Genus	serum_cytokines	0.118	0.632	no	no	no	no	no	no	HC
Homovanillic acid+urine	MIP-1b	Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2-MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.45	0.632	no	no	no	no	no	no	HC
Homovanillic acid+urine	MIP-1b	Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2-MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.45	0.632	no	no	no	no	no	no	HC
TDCA+blood	MIP-1b	TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.155	0.632	no	up	no	no	no	no	HC
iso-LCA+blood	MIP-1b	iso-LCA+blood-n3+blood-n6/n3+blood+TMAO+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.507	0.632	no	no	no	no	no	no	HC
¦Ø-MCA+stool	MIP-1b	¦Ø-MCA+stool-Butyric acid+stool-L-Phenylalanine+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.919	0.632	no	no	no	no	no	no	HC
¦Ø-MCA+stool	MIP-1b	¦Ø-MCA+stool-iso-DCA+stool-L-Tryptophan+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.919	0.632	no	no	no	no	no	no	HC
¦Ø-MCA+stool	MIP-1b	¦Ø-MCA+stool-Butyric acid+stool-L-Tryptophan+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.919	0.632	no	no	no	no	no	no	HC
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool-14:0/18:2-PC+blood-Betaine+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	HC
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool+n6/n3+blood+TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	HC
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool-14:0/18:2-PC+blood-TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	HC
Phenylacetic acid+stool	MIP-1b	Phenylacetic acid+stool-22:6n3+blood-TMAO+blood-MIP-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.632	no	no	no	no	no	no	HC
Gemmiger	MIP-1b	Gemmiger-L-Phenylalanine+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.595	0.632	no	no	no	no	no	no	HC
Gemmiger	MIP-1b	Gemmiger-L-Tyrosine+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.595	0.632	no	no	no	no	no	no	HC
Gemmiger	MIP-1b	Gemmiger-Cysteine+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.595	0.632	no	no	no	no	no	no	HC
Gemmiger	MIP-1b	Gemmiger-L-Tryptophan+stool+MIP-1b	Indirect	Genus	serum_cytokines	0.595	0.632	no	no	no	no	no	no	HC
GDCA+stool	MIP-1b	GDCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.632	no	no	no	no	no	no	HC
L-Tyrosine+stool	MIP-1b	L-Tyrosine+stool+MIP-1b	Direct	stool_cometabolism	serum_cytokines	0.44	0.632	no	no	no	no	no	no	HC
CDCA+stool	MIP-1b	CDCA+stool+UDCA+stool-TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	HC
CDCA+stool	MIP-1b	CDCA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	HC
CDCA+stool	MIP-1b	CDCA+stool+nutriCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	HC
CDCA+stool	MIP-1b	CDCA+stool+HCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	HC
CDCA+stool	MIP-1b	CDCA+stool+GCA+stool+16:0/22:6-PE+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	HC
CDCA+stool	MIP-1b	CDCA+stool+16:0/18:3-PC+blood-L-Tryptophan+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	HC
CDCA+stool	MIP-1b	CDCA+stool-DCA+stool-L-Tyrosine+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	HC
CDCA+stool	MIP-1b	CDCA+stool+GCA+stool-L-Methionine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	HC
CDCA+stool	MIP-1b	CDCA+stool-DCA+stool-L-Tryptophan+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	HC
CDCA+stool	MIP-1b	CDCA+stool-iso-DCA+stool-L-Tryptophan+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	HC
CDCA+stool	MIP-1b	CDCA+stool-DCA+stool-L-Phenylalanine+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.632	no	no	no	no	no	no	HC
CA+stool	MIP-1b	CA+stool+16:0/18:3-PC+blood-L-Tryptophan+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	HC
CA+stool	MIP-1b	CA+stool+UDCA+stool-TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	HC
CA+stool	MIP-1b	CA+stool-iso-DCA+stool-L-Tryptophan+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	HC
CA+stool	MIP-1b	CA+stool-DCA+stool-L-Tryptophan+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	HC
CA+stool	MIP-1b	CA+stool-18:1/16:0-PC+blood-18:1/18:1-PE+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	HC
CA+stool	MIP-1b	CA+stool+nutriCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	HC
CA+stool	MIP-1b	CA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	HC
CA+stool	MIP-1b	CA+stool+GDCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	HC
CA+stool	MIP-1b	CA+stool+HCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	HC
CA+stool	MIP-1b	CA+stool-18:1/16:0-PC+blood+L-Phenylalanine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	HC
CA+stool	MIP-1b	CA+stool+GCA+stool-L-Methionine+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	HC
CA+stool	MIP-1b	CA+stool+GCA+stool+16:0/22:6-PE+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	HC
CA+stool	MIP-1b	CA+stool-DCA+stool-L-Tyrosine+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	HC
CA+stool	MIP-1b	CA+stool-DCA+stool-L-Phenylalanine+stool+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.632	no	no	no	no	no	no	HC
HDCA+blood	MIP-1b	HDCA+blood+L-Tryptophan+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.483	0.632	no	no	no	no	no	no	HC
TLCA+stool	MIP-1b	TLCA+stool+IL-9+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.243	0.632	no	no	no	no	no	no	HC
UDCA+stool	MIP-1b	UDCA+stool-TMAO+blood-MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.632	no	no	no	no	no	no	HC
LCA+blood	MIP-1b	LCA+blood-n3+blood-n6/n3+blood+TMAO+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.884	0.632	no	no	no	no	no	no	HC
nutriCA+stool	MIP-1b	nutriCA+stool+d18:1-20:0-SM+blood+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.632	no	no	no	no	no	no	HC
GDCA+blood	MIP-1b	GDCA+blood+TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13-IL-2-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.632	0.632	no	no	no	no	no	no	HC
P-hydroxyhippuric acid+urine	MIP-1b	P-hydroxyhippuric acid+urine-FGF basic-IL-13-IL-2-MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.436	0.632	no	no	no	no	no	no	HC
acetic acid C2+blood	MIP-1b	acetic acid C2+blood+L-2-Aminobutyric acid+blood+L-Tyrosine+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.632	up	dn	no	no	no	no	HC
acetic acid C2+blood	MIP-1b	acetic acid C2+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.632	up	dn	no	no	no	no	HC
acetic acid C2+blood	MIP-1b	acetic acid C2+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.632	up	dn	no	no	no	no	HC
isovaleric acid iso-C5+blood	MIP-1b	isovaleric acid iso-C5+blood+Sarcosine+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2-MIP-1b	Indirect	serum_scfa	serum_cytokines	0.117	0.632	no	no	no	no	no	no	HC
L-Phenylalanine+urine	MIP-1b	L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2-MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.0908	0.632	no	up	no	no	no	no	HC
Clostridium	MIP-1b	Clostridium+MIP-1b	Direct	Genus	serum_cytokines	0.925	0.632	no	no	no	no	no	no	HC
T-¦Á-MCA+stool	MIP-1b	T-¦Á-MCA+stool-TLCA+stool+IL-9+MIP-1b	Indirect	stool_bileacids	serum_cytokines	0.48	0.632	no	no	no	no	no	no	HC
12-ketoDCA+blood	MIP-1b	12-ketoDCA+blood-isocapric acid iso-C6+blood+L-Tyrosine+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.632	no	no	no	no	no	no	HC
12-ketoDCA+blood	MIP-1b	12-ketoDCA+blood-DPA+blood-TMAO+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.632	no	no	no	no	no	no	HC
12-ketoDCA+blood	MIP-1b	12-ketoDCA+blood+16:0/16:1-PI+blood-TMAO+blood-MIP-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.632	no	no	no	no	no	no	HC
Butyricicoccus	MIP-1b	Butyricicoccus+d18:1-22:0-SM+blood+IL-9+MIP-1b	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	HC
Butyricicoccus	MIP-1b	Butyricicoccus-HDCA+blood+L-Tryptophan+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	HC
Butyricicoccus	MIP-1b	Butyricicoccus-Salivary secretion+Alcoholism-MIP-1b	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	HC
Butyricicoccus	MIP-1b	Butyricicoccus-Salivary secretion+Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.852	0.632	no	no	no	no	no	no	HC
3-Hydroxy-L-kynurenine+urine	MIP-1b	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine+FGF basic-IL-13-IL-2-MIP-1b	Indirect	urine_cometabolism	serum_cytokines	0.401	0.632	no	no	no	no	no	no	HC
Wautersiella	MIP-1b	Wautersiella+Butyricicoccus+d18:1-22:0-SM+blood+IL-9+MIP-1b	Indirect	Genus	serum_cytokines	0.289	0.632	no	no	no	no	no	no	HC
Wautersiella	MIP-1b	Wautersiella+Butyricicoccus-HDCA+blood+L-Tryptophan+blood-MIP-1b	Indirect	Genus	serum_cytokines	0.289	0.632	no	no	no	no	no	no	HC
Wautersiella	MIP-1b	Wautersiella+Butyricicoccus-Salivary secretion+Alcoholism-MIP-1b	Indirect	Genus	serum_cytokines	0.289	0.632	no	no	no	no	no	no	HC
Wautersiella	MIP-1b	Wautersiella+Butyricicoccus-Salivary secretion+Mineral absorption-MIP-1b	Indirect	Genus	serum_cytokines	0.289	0.632	no	no	no	no	no	no	HC
Blautia	IL-9	Blautia-Butyric acid+stool-d18:1-22:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	1.36E-05	0.906	up	dn	dn	no	no	no	HC
Blautia	IL-9	Blautia-18:1-LPE+blood-24:1+blood-IL-9	Indirect	Genus	serum_cytokines	1.36E-05	0.906	up	dn	dn	no	no	no	HC
Blautia	IL-9	Blautia+Peroxisome-Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	1.36E-05	0.906	up	dn	dn	no	no	no	HC
Blautia	IL-9	Blautia-Cushing syndrome+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	1.36E-05	0.906	up	dn	dn	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides+Carbon metabolism-Necroptosis-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides+18:0/22:6-PA+blood-L-Alanine+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides-Phosphatidylinositol signaling system+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides+Biosynthesis of amino acids-L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides-RNA degradation+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides-Colorectal cancer+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides+Carbon metabolism-L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides+Glycolysis / Gluconeogenesis-L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides+16:1/18:2-PG+blood+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides-Pathways in cancer+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides-mRNA surveillance pathway+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides-9-HODE+blood-L-Ornithine+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides+18:0/22:6-PA+blood+24:1+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides+Ethanolamine+blood+L-Asparagine+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides-9-HODE+blood-L-Asparagine+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides+Ethanolamine+blood+L-Glutamine+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides+Ethanolamine+blood+L-Glutamic acid+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides+Carbon metabolism-Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Parabacteroides	IL-9	Parabacteroides+Ethanolamine+blood+L-Lysine+blood-IL-9	Indirect	Genus	serum_cytokines	4.19E-05	0.906	no	up	up	no	no	no	HC
Dorea	IL-9	Dorea-Endocrine resistance+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	HC
Dorea	IL-9	Dorea-GnRH signaling pathway+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	HC
Dorea	IL-9	Dorea-Endocrine resistance+Necroptosis-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	HC
Dorea	IL-9	Dorea+Legionellosis-L-Lysine+blood-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	HC
Dorea	IL-9	Dorea-Fc epsilon RI signaling pathway+L-Lysine+blood-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	HC
Dorea	IL-9	Dorea-VEGF signaling pathway+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	HC
Dorea	IL-9	Dorea+Legionellosis-L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	HC
Dorea	IL-9	Dorea-Fc epsilon RI signaling pathway+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	HC
Dorea	IL-9	"Dorea-Growth hormone synthesis, secretion and action+L-Methionine+blood-IL-9"	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	HC
Dorea	IL-9	Dorea+Legionellosis-Cystine+blood-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	HC
Dorea	IL-9	Dorea-18:0-LPC+blood-Cystine+blood-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	HC
Dorea	IL-9	Dorea-18:0-LPC+blood-L-Glutamine+blood-IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	HC
Dorea	IL-9	Dorea+16:0/18:3-PC+blood+d18:1-20:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	HC
Dorea	IL-9	"Dorea-Growth hormone synthesis, secretion and action-d18:1-20:0-SM+blood+IL-9"	Indirect	Genus	serum_cytokines	0.00362	0.906	up	no	dn	no	no	no	HC
Faecalibacterium	IL-9	Faecalibacterium-TLCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.0039	0.906	no	dn	dn	no	no	no	HC
isocapric acid iso-C6+blood	IL-9	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood-IL-9	Indirect	serum_scfa	serum_cytokines	0.0458	0.906	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	IL-9	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood-IL-9	Indirect	serum_scfa	serum_cytokines	0.0458	0.906	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	IL-9	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-IL-9	Indirect	serum_scfa	serum_cytokines	0.0458	0.906	no	no	dn	no	no	no	HC
Bacteroides	IL-9	Bacteroides+AGE-RAGE signaling pathway in diabetic complications+L-Lysine+blood-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	"Bacteroides+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-9"	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides-cAMP signaling pathway+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides-L-Homocystine+blood+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides+AGE-RAGE signaling pathway in diabetic complications+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides+Biosynthesis of amino acids-L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides-cAMP signaling pathway+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides-Mitophagy - animal+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides-Ribosome+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides-Thermogenesis+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides+Graft-versus-host disease+Cystine+blood-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides+Allograft rejection+Cystine+blood-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides+Type I diabetes mellitus+Cystine+blood-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides+Endocytosis+Cystine+blood-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides+AGE-RAGE signaling pathway in diabetic complications+Cystine+blood-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides+Autoimmune thyroid disease+Cystine+blood-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides-Mitophagy - animal+Ferroptosis-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides+nutriCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides-Mitophagy - animal-d18:1-20:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides-Mitophagy - animal+Malaria-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides-Shigellosis+Malaria-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides-Mitophagy - animal+Necroptosis-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Bacteroides	IL-9	Bacteroides-Ribosome+Necroptosis-IL-9	Indirect	Genus	serum_cytokines	0.000267	0.906	dn	dn	up	no	no	no	HC
Propionic acid+stool	IL-9	Propionic acid+stool+16:0/18:2-PI+blood-L-Glutamine+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.0436	0.906	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-9	Propionic acid+stool-18:0/20:5-PC+blood+Cystine+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.0436	0.906	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-9	Propionic acid+stool-18:0/20:5-PC+blood+L-Lysine+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.0436	0.906	dn	no	up	no	no	no	HC
[Ruminococcus]	IL-9	[Ruminococcus]+IL-9	Direct	Genus	serum_cytokines	0.0679	0.906	no	no	dn	no	no	no	HC
GUDCA+blood	IL-9	GUDCA+blood-iso-DCA+blood+L-Histidine+blood+L-Methionine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.0766	0.906	no	no	dn	no	no	no	HC
GUDCA+blood	IL-9	GUDCA+blood-iso-DCA+blood+L-Histidine+blood+L-Lysine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.0766	0.906	no	no	dn	no	no	no	HC
Acetic acid+stool	IL-9	Acetic acid+stool+Butyric acid+stool-d18:1-22:0-SM+blood+IL-9	Indirect	stool_scfa	serum_cytokines	0.0656	0.906	dn	no	no	no	no	no	HC
Acetic acid+stool	IL-9	Acetic acid+stool-18:0/20:5-PC+blood+L-Lysine+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.0656	0.906	dn	no	no	no	no	no	HC
Acetic acid+stool	IL-9	Acetic acid+stool-18:0/20:5-PC+blood+Cystine+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.0656	0.906	dn	no	no	no	no	no	HC
Acetic acid+stool	IL-9	Acetic acid+stool-L-Homocystine+blood+L-Methionine+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.0656	0.906	dn	no	no	no	no	no	HC
Acetic acid+stool	IL-9	Acetic acid+stool+16:0/18:2-PI+blood-L-Glutamine+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.0656	0.906	dn	no	no	no	no	no	HC
Alistipes	IL-9	Alistipes+L-Glutamine+blood-IL-9	Indirect	Genus	serum_cytokines	0.0114	0.906	no	up	no	no	no	no	HC
Butyricimonas	IL-9	Butyricimonas-Eotaxin-IL-9	Indirect	Genus	serum_cytokines	0.17	0.906	no	no	no	no	no	no	HC
Butyricimonas	IL-9	Butyricimonas+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.17	0.906	no	no	no	no	no	no	HC
Collinsella	IL-9	Collinsella+18:0/18:0-PS+blood+18:1/18:1-PE+blood+IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	HC
Collinsella	IL-9	Collinsella+18:0/18:0-PS+blood-L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	HC
Collinsella	IL-9	Collinsella+18:0/18:0-PS+blood-L-Alanine+blood-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	HC
Collinsella	IL-9	Collinsella+Porphyrin and chlorophyll metabolism+Malaria-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	HC
Collinsella	IL-9	"Collinsella+Glycine, serine and threonine metabolism-L-Lysine+blood-IL-9"	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	HC
Collinsella	IL-9	Collinsella+Porphyrin and chlorophyll metabolism+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	HC
Collinsella	IL-9	Collinsella+Porphyrin and chlorophyll metabolism+Necroptosis-IL-9	Indirect	Genus	serum_cytokines	0.128	0.906	no	no	no	no	no	no	HC
iso-DCA+stool	IL-9	iso-DCA+stool+T-¦Á-MCA+stool-TLCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.155	0.906	no	no	no	no	no	no	HC
iso-DCA+stool	IL-9	iso-DCA+stool-nutriCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.155	0.906	no	no	no	no	no	no	HC
iso-DCA+stool	IL-9	iso-DCA+stool-L-Tryptophan+stool+18:1/18:1-PE+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.155	0.906	no	no	no	no	no	no	HC
LCA+stool	IL-9	LCA+stool+16:0/18:2-PC+blood-18:1/18:1-PE+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.314	0.906	no	no	no	no	no	no	HC
LCA+stool	IL-9	LCA+stool+18:1/16:0-PC+blood-18:1/18:1-PE+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.314	0.906	no	no	no	no	no	no	HC
LCA+stool	IL-9	LCA+stool+T-¦Á-MCA+stool-TLCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.314	0.906	no	no	no	no	no	no	HC
LCA+stool	IL-9	"LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+IL-9"	Indirect	stool_bileacids	serum_cytokines	0.314	0.906	no	no	no	no	no	no	HC
LCA+stool	IL-9	LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.314	0.906	no	no	no	no	no	no	HC
LCA+stool	IL-9	LCA+stool+16:0/18:2-PC+blood+L-Methionine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.314	0.906	no	no	no	no	no	no	HC
Akkermansia	IL-9	Akkermansia+TLCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.23	0.906	no	no	no	no	no	no	HC
Bifidobacterium	IL-9	Bifidobacterium-L-Ornithine+blood-IL-9	Indirect	Genus	serum_cytokines	0.105	0.906	no	dn	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus+Ubiquitin mediated proteolysis-d18:1-20:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus+Ubiquitin mediated proteolysis+Ferroptosis-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus-Lysosome+24:1+blood-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus-Lysosome+Cystine+blood-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus-Endocytosis+Cystine+blood-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus+Ubiquitin mediated proteolysis+Necroptosis-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus+Endocrine resistance+Necroptosis-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus+Ribosome+Necroptosis-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus+Ubiquitin mediated proteolysis+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus+Thyroid hormone synthesis+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus+Thermogenesis+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus+Endocrine resistance+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus-NOD-like receptor signaling pathway-Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus+Dopaminergic synapse+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus-Osteoclast differentiation-Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus+Ribosome+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus-Peroxisome-Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus-Fc gamma R-mediated phagocytosis-Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus+Thyroid hormone synthesis+Malaria-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus-cGMP-PKG signaling pathway+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus+Dopaminergic synapse+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus-Pancreatic cancer+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus-Biosynthesis of amino acids-L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
Ruminococcus	IL-9	Ruminococcus+18:1/18:1-PC+blood-18:1/18:1-PE+blood+IL-9	Indirect	Genus	serum_cytokines	0.335	0.906	no	no	no	no	no	no	HC
GCDCA+blood	IL-9	GCDCA+blood+L-Alanine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.31	0.906	no	no	no	no	no	no	HC
[Prevotella]	IL-9	[Prevotella]-Glutamatergic synapse+Malaria-IL-9	Indirect	Genus	serum_cytokines	0.367	0.906	no	no	no	no	no	no	HC
[Prevotella]	IL-9	[Prevotella]-Glutamatergic synapse-d18:1-22:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.367	0.906	no	no	no	no	no	no	HC
[Prevotella]	IL-9	[Prevotella]+Ethanolamine+blood+L-Asparagine+blood-IL-9	Indirect	Genus	serum_cytokines	0.367	0.906	no	no	no	no	no	no	HC
[Prevotella]	IL-9	"[Prevotella]-Growth hormone synthesis, secretion and action-d18:1-20:0-SM+blood+IL-9"	Indirect	Genus	serum_cytokines	0.367	0.906	no	no	no	no	no	no	HC
[Prevotella]	IL-9	[Prevotella]+24:0+blood+d18:1-20:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.367	0.906	no	no	no	no	no	no	HC
[Prevotella]	IL-9	[Prevotella]+Ethanolamine+blood+L-Glutamic acid+blood-IL-9	Indirect	Genus	serum_cytokines	0.367	0.906	no	no	no	no	no	no	HC
[Prevotella]	IL-9	[Prevotella]+Ethanolamine+blood+L-Glutamine+blood-IL-9	Indirect	Genus	serum_cytokines	0.367	0.906	no	no	no	no	no	no	HC
[Prevotella]	IL-9	[Prevotella]+GLCA+blood+L-Glutamine+blood-IL-9	Indirect	Genus	serum_cytokines	0.367	0.906	no	no	no	no	no	no	HC
[Prevotella]	IL-9	[Prevotella]+Ethanolamine+blood+L-Lysine+blood-IL-9	Indirect	Genus	serum_cytokines	0.367	0.906	no	no	no	no	no	no	HC
[Prevotella]	IL-9	"[Prevotella]-Growth hormone synthesis, secretion and action+L-Methionine+blood-IL-9"	Indirect	Genus	serum_cytokines	0.367	0.906	no	no	no	no	no	no	HC
[Prevotella]	IL-9	[Prevotella]-Aldosterone synthesis and secretion+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.367	0.906	no	no	no	no	no	no	HC
[Prevotella]	IL-9	[Prevotella]-GnRH signaling pathway+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.367	0.906	no	no	no	no	no	no	HC
[Prevotella]	IL-9	[Prevotella]-Glutamatergic synapse+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.367	0.906	no	no	no	no	no	no	HC
[Prevotella]	IL-9	[Prevotella]-Gap junction+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.367	0.906	no	no	no	no	no	no	HC
ACA+blood	IL-9	ACA+blood-d18:1-14:0-SM+blood-L-Ornithine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.338	0.906	no	no	no	no	no	no	HC
ACA+blood	IL-9	ACA+blood-d18:1-14:0-SM+blood-L-Methionine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.338	0.906	no	no	no	no	no	no	HC
ACA+blood	IL-9	ACA+blood-d18:1-14:0-SM+blood+d18:1-20:0-SM+blood+IL-9	Indirect	serum_bileacids	serum_cytokines	0.338	0.906	no	no	no	no	no	no	HC
DCA+stool	IL-9	DCA+stool-L-Tyrosine+stool+18:1/18:1-PE+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.195	0.906	no	no	no	no	no	no	HC
DCA+stool	IL-9	DCA+stool-L-Phenylalanine+stool+18:1/18:1-PE+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.195	0.906	no	no	no	no	no	no	HC
DCA+stool	IL-9	DCA+stool-L-Tryptophan+stool+18:1/18:1-PE+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.195	0.906	no	no	no	no	no	no	HC
DCA+stool	IL-9	DCA+stool-DL-methionine sulfoxide+blood+L-Ornithine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.195	0.906	no	no	no	no	no	no	HC
DCA+stool	IL-9	DCA+stool-DL-methionine sulfoxide+blood+L-Alanine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.195	0.906	no	no	no	no	no	no	HC
DCA+stool	IL-9	DCA+stool-8-HETE+blood+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.195	0.906	no	no	no	no	no	no	HC
Butyric acid+stool	IL-9	Butyric acid+stool-d18:1-22:0-SM+blood+IL-9	Indirect	stool_scfa	serum_cytokines	0.102	0.906	dn	no	no	no	no	no	HC
4-hydroxybenzoic acid+stool	IL-9	4-hydroxybenzoic acid+stool+18:0/18:2-PI+blood+18:1/18:1-PE+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.906	no	dn	no	no	no	no	HC
4-hydroxybenzoic acid+stool	IL-9	4-hydroxybenzoic acid+stool+Cysteine+blood+L-Lysine+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.906	no	dn	no	no	no	no	HC
4-hydroxybenzoic acid+stool	IL-9	4-hydroxybenzoic acid+stool+18:0/18:2-PI+blood-Cystine+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.906	no	dn	no	no	no	no	HC
4-hydroxybenzoic acid+stool	IL-9	4-hydroxybenzoic acid+stool+18:0/18:2-PI+blood-L-Glutamine+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.906	no	dn	no	no	no	no	HC
4-hydroxybenzoic acid+stool	IL-9	4-hydroxybenzoic acid+stool-L-Homocystine+blood+L-Methionine+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.906	no	dn	no	no	no	no	HC
4-hydroxybenzoic acid+stool	IL-9	4-hydroxybenzoic acid+stool+Cysteine+blood+L-Methionine+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.906	no	dn	no	no	no	no	HC
4-hydroxybenzoic acid+stool	IL-9	4-hydroxybenzoic acid+stool+HCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.906	no	dn	no	no	no	no	HC
GCA+blood	IL-9	GCA+blood+L-Alanine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.16	0.906	no	no	no	no	no	no	HC
ACA+stool	IL-9	ACA+stool-18:0/18:2-PI+blood-Cystine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.417	0.906	no	no	no	no	no	no	HC
ACA+stool	IL-9	ACA+stool-18:0/18:2-PI+blood-L-Glutamine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.417	0.906	no	no	no	no	no	no	HC
ACA+stool	IL-9	ACA+stool-18:0/18:2-PI+blood+18:1/18:1-PE+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.417	0.906	no	no	no	no	no	no	HC
CDCA+blood	IL-9	CDCA+blood-Creatinine+blood+L-Glutamic acid+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.506	0.906	no	no	no	no	no	no	HC
CDCA+blood	IL-9	CDCA+blood+GCDCA+blood+L-Alanine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.506	0.906	no	no	no	no	no	no	HC
CDCA+blood	IL-9	CDCA+blood-Creatinine+blood+L-Asparagine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.506	0.906	no	no	no	no	no	no	HC
CDCA+blood	IL-9	CDCA+blood-Creatinine+blood+L-Glutamine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.506	0.906	no	no	no	no	no	no	HC
CDCA+blood	IL-9	CDCA+blood-L-2-Aminobutyric acid+blood+L-Methionine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.506	0.906	no	no	no	no	no	no	HC
CDCA+blood	IL-9	CDCA+blood-Creatinine+blood+L-Methionine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.506	0.906	no	no	no	no	no	no	HC
CDCA+blood	IL-9	CDCA+blood-d18:1-18:0-SM+blood+d18:1-20:0-SM+blood+IL-9	Indirect	serum_bileacids	serum_cytokines	0.506	0.906	no	no	no	no	no	no	HC
CDCA+blood	IL-9	CDCA+blood-d18:1-18:1-SM+blood+d18:1-20:0-SM+blood+IL-9	Indirect	serum_bileacids	serum_cytokines	0.506	0.906	no	no	no	no	no	no	HC
CDCA+blood	IL-9	CDCA+blood-L-2-Aminobutyric acid+blood+L-Lysine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.506	0.906	no	no	no	no	no	no	HC
CDCA+blood	IL-9	CDCA+blood-Creatinine+blood+L-Lysine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.506	0.906	no	no	no	no	no	no	HC
capric acid C6+blood	IL-9	capric acid C6+blood-Cystine+blood-IL-9	Indirect	serum_scfa	serum_cytokines	0.433	0.906	no	no	no	no	no	no	HC
Prevotella	IL-9	Prevotella-24:1+blood-IL-9	Indirect	Genus	serum_cytokines	0.287	0.906	no	no	no	no	no	no	HC
TCA+blood	IL-9	"TCA+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-9"	Indirect	serum_bileacids	serum_cytokines	0.339	0.906	no	no	no	no	no	no	HC
iso-DCA+blood	IL-9	iso-DCA+blood+L-Histidine+blood+L-Methionine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.38	0.906	no	no	no	no	no	no	HC
iso-DCA+blood	IL-9	iso-DCA+blood+L-Histidine+blood+L-Lysine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.38	0.906	no	no	no	no	no	no	HC
HCA+stool	IL-9	HCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.155	0.906	no	no	no	no	no	no	HC
Roseburia	IL-9	Roseburia+Malaria-IL-9	Indirect	Genus	serum_cytokines	0.495	0.906	no	no	no	no	no	no	HC
12-ketoDCA+stool	IL-9	12-ketoDCA+stool-Cystine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.505	0.906	no	no	no	no	no	no	HC
GLCA+blood	IL-9	GLCA+blood+L-Glutamine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.319	0.906	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-9	L-Tryptophan+stool+18:1/18:1-PE+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.557	0.906	no	no	no	no	no	no	HC
CA+blood	IL-9	CA+blood-L-Isoleucine+blood+L-Lysine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.606	0.906	no	no	no	no	no	no	HC
GUDCA+stool	IL-9	GUDCA+stool+L-Tryptophan+stool+18:1/18:1-PE+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.0085	0.906	no	dn	no	no	no	no	HC
L-Phenylalanine+stool	IL-9	L-Phenylalanine+stool+18:1/18:1-PE+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.398	0.906	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-9	butyric acid C4+blood+Cystine+blood-IL-9	Indirect	serum_scfa	serum_cytokines	0.407	0.906	no	no	no	no	no	no	HC
GCA+stool	IL-9	GCA+stool-L-Methionine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.0809	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus-Influenza A+L-Lysine+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus-Choline+blood+L-Lysine+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus-Influenza A+L-Glutamic acid+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus-Choline+blood+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus+Primary immunodeficiency-L-Glutamine+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus+Central carbon metabolism in cancer-L-Glutamine+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus+16:0/20:4-PI+blood-L-Glutamine+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus-Influenza A+L-Glutamine+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus+Primary immunodeficiency-L-Ornithine+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus+Central carbon metabolism in cancer-L-Ornithine+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus+3-(3-Hydroxyphenyl)propanoic acid+stool-L-Ornithine+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus+Ribosome biogenesis in eukaryotes-L-Ornithine+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus-Lysosome+24:1+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus+Primary immunodeficiency+18:1/18:1-PE+blood+IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus+Primary immunodeficiency-L-Asparagine+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus-Influenza A+L-Asparagine+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus+Primary immunodeficiency-Cystine+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus-Lysosome+Cystine+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus+Ribosome biogenesis in eukaryotes-Cystine+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Coprococcus	IL-9	Coprococcus-Influenza A+Cystine+blood-IL-9	Indirect	Genus	serum_cytokines	0.612	0.906	no	no	no	no	no	no	HC
Oscillospira	IL-9	Oscillospira-Human T-cell leukemia virus 1 infection+d18:1-22:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	HC
Oscillospira	IL-9	Oscillospira-Salmonella infection+d18:1-20:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	HC
Oscillospira	IL-9	Oscillospira-nutriCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	HC
Oscillospira	IL-9	Oscillospira-HCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	HC
Oscillospira	IL-9	Oscillospira-Human T-cell leukemia virus 1 infection+d18:1-20:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	HC
Oscillospira	IL-9	Oscillospira-Antigen processing and presentation+d18:1-20:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	HC
Oscillospira	IL-9	Oscillospira+L-Homocystine+blood+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	HC
Oscillospira	IL-9	Oscillospira-9-HODE+blood-L-Ornithine+blood-IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	HC
Oscillospira	IL-9	Oscillospira-9-HODE+blood-L-Asparagine+blood-IL-9	Indirect	Genus	serum_cytokines	0.62	0.906	no	no	no	no	no	no	HC
HCA+blood	IL-9	HCA+blood-L-2-Aminobutyric acid+blood+L-Lysine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.544	0.906	no	no	no	no	no	no	HC
HCA+blood	IL-9	HCA+blood-L-Isoleucine+blood+L-Lysine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.544	0.906	no	no	no	no	no	no	HC
HCA+blood	IL-9	HCA+blood-L-2-Aminobutyric acid+blood+L-Methionine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.544	0.906	no	no	no	no	no	no	HC
iso-LCA+stool	IL-9	iso-LCA+stool-16:0/18:3-PC+blood+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.72	0.906	no	no	no	no	no	no	HC
iso-LCA+stool	IL-9	iso-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.72	0.906	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-9	2-methyl-butyric acid m-C4+blood+heptanoic acid C7+blood+L-Asparagine+blood-IL-9	Indirect	serum_scfa	serum_cytokines	0.262	0.906	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-9	2-methyl-butyric acid m-C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-IL-9	Indirect	serum_scfa	serum_cytokines	0.262	0.906	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-9	2-methyl-butyric acid m-C4+blood+decanoic acid C10+blood+L-Methionine+blood-IL-9	Indirect	serum_scfa	serum_cytokines	0.262	0.906	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-9	2-methyl-butyric acid m-C4+blood+butyric acid C4+blood+Cystine+blood-IL-9	Indirect	serum_scfa	serum_cytokines	0.262	0.906	no	no	no	no	no	no	HC
DCA+blood	IL-9	"DCA+blood-n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-9"	Indirect	serum_bileacids	serum_cytokines	0.122	0.906	no	no	no	no	no	no	HC
DCA+blood	IL-9	DCA+blood-isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.122	0.906	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-9	3-(3-Hydroxyphenyl)propanoic acid+stool-L-Ornithine+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.33	0.906	no	no	no	no	no	no	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-9	"3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-9"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.906	up	up	no	no	no	no	HC
GLCA+stool	IL-9	GLCA+stool-LCA+stool+T-¦Á-MCA+stool-TLCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.617	0.906	no	no	no	no	no	no	HC
GLCA+stool	IL-9	"GLCA+stool-LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+IL-9"	Indirect	stool_bileacids	serum_cytokines	0.617	0.906	no	no	no	no	no	no	HC
GLCA+stool	IL-9	GLCA+stool-LCA+stool+18:1/16:0-PC+blood-18:1/18:1-PE+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.617	0.906	no	no	no	no	no	no	HC
GLCA+stool	IL-9	GLCA+stool-LCA+stool+16:0/18:2-PC+blood-18:1/18:1-PE+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.617	0.906	no	no	no	no	no	no	HC
GLCA+stool	IL-9	GLCA+stool-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.617	0.906	no	no	no	no	no	no	HC
GLCA+stool	IL-9	GLCA+stool-iso-LCA+stool-nutriCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.617	0.906	no	no	no	no	no	no	HC
GLCA+stool	IL-9	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.617	0.906	no	no	no	no	no	no	HC
GLCA+stool	IL-9	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Methionine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.617	0.906	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-9	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+18:1/18:1-PE+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.304	0.906	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-9	Indole-3-Acetic acid+stool+L-Tryptophan+stool+18:1/18:1-PE+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.304	0.906	no	no	no	no	no	no	HC
TCA+stool	IL-9	TCA+stool-Creatinine+blood+L-Glutamic acid+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.458	0.906	no	no	no	no	no	no	HC
TCA+stool	IL-9	TCA+stool+18:3n6+blood-L-Lysine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.458	0.906	no	no	no	no	no	no	HC
TCA+stool	IL-9	TCA+stool-Creatinine+blood+L-Lysine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.458	0.906	no	no	no	no	no	no	HC
TCA+stool	IL-9	TCA+stool-Choline+blood+L-Lysine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.458	0.906	no	no	no	no	no	no	HC
TCA+stool	IL-9	TCA+stool+18:3n6+blood-L-Methionine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.458	0.906	no	no	no	no	no	no	HC
TCA+stool	IL-9	TCA+stool-16:0/18:2-PC+blood+L-Methionine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.458	0.906	no	no	no	no	no	no	HC
TCA+stool	IL-9	TCA+stool-Creatinine+blood+L-Methionine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.458	0.906	no	no	no	no	no	no	HC
TCA+stool	IL-9	TCA+stool-Choline+blood+L-Methionine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.458	0.906	no	no	no	no	no	no	HC
TCA+stool	IL-9	TCA+stool-18:1/18:1-PC+blood-18:1/18:1-PE+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.458	0.906	no	no	no	no	no	no	HC
TCA+stool	IL-9	TCA+stool-16:0/18:2-PC+blood-18:1/18:1-PE+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.458	0.906	no	no	no	no	no	no	HC
TCA+stool	IL-9	TCA+stool-18:1/16:0-PC+blood-18:1/18:1-PE+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.458	0.906	no	no	no	no	no	no	HC
TCA+stool	IL-9	TCA+stool-Creatinine+blood+L-Asparagine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.458	0.906	no	no	no	no	no	no	HC
TCA+stool	IL-9	TCA+stool+16:0/20:4-PI+blood-L-Glutamine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.458	0.906	no	no	no	no	no	no	HC
TCA+stool	IL-9	TCA+stool-Creatinine+blood+L-Glutamine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.458	0.906	no	no	no	no	no	no	HC
HDCA+stool	IL-9	HDCA+stool+16:0/20:4-PC+blood+24:1+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.176	0.906	no	no	no	no	no	no	HC
HDCA+stool	IL-9	HDCA+stool+20:3/16:0-PC+blood+24:1+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.176	0.906	no	no	no	no	no	no	HC
HDCA+stool	IL-9	HDCA+stool+T-¦Á-MCA+stool-TLCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.176	0.906	no	no	no	no	no	no	HC
HDCA+stool	IL-9	HDCA+stool+16:0/20:4-PC+blood-18:1/18:1-PE+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.176	0.906	no	no	no	no	no	no	HC
HDCA+stool	IL-9	HDCA+stool+Ethanolamine+blood+L-Glutamic acid+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.176	0.906	no	no	no	no	no	no	HC
HDCA+stool	IL-9	HDCA+stool+Ethanolamine+blood+L-Asparagine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.176	0.906	no	no	no	no	no	no	HC
HDCA+stool	IL-9	HDCA+stool+Ethanolamine+blood+L-Lysine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.176	0.906	no	no	no	no	no	no	HC
HDCA+stool	IL-9	HDCA+stool-16:0/18:3-PC+blood+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.176	0.906	no	no	no	no	no	no	HC
HDCA+stool	IL-9	HDCA+stool-nutriCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.176	0.906	no	no	no	no	no	no	HC
HDCA+stool	IL-9	HDCA+stool+16:0/20:4-PC+blood+L-Glutamine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.176	0.906	no	no	no	no	no	no	HC
HDCA+stool	IL-9	HDCA+stool+Ethanolamine+blood+L-Glutamine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.176	0.906	no	no	no	no	no	no	HC
HDCA+stool	IL-9	HDCA+stool+20:3/16:0-PC+blood+L-Glutamine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.176	0.906	no	no	no	no	no	no	HC
Lachnospira	IL-9	Lachnospira+JAK-STAT signaling pathway-Malaria-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	HC
Lachnospira	IL-9	Lachnospira-Herpes simplex virus 1 infection+d18:1-22:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	HC
Lachnospira	IL-9	Lachnospira+18:0/18:1-PE+blood-24:1+blood-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	HC
Lachnospira	IL-9	Lachnospira-Inflammatory bowel disease+24:1+blood-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	HC
Lachnospira	IL-9	Lachnospira-Intestinal immune network for IgA production+TLCA+stool+IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	HC
Lachnospira	IL-9	Lachnospira+18:0/18:1-PE+blood+18:1/18:1-PE+blood+IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	HC
Lachnospira	IL-9	Lachnospira+18:0/22:6-PE+blood+18:1/18:1-PE+blood+IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	HC
Lachnospira	IL-9	Lachnospira+16:0/22:6-PE+blood+18:1/18:1-PE+blood+IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	HC
Lachnospira	IL-9	Lachnospira-Intestinal immune network for IgA production-18:1/18:1-PE+blood+IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	HC
Lachnospira	IL-9	Lachnospira+18:0/18:1-PE+blood-L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	HC
Lachnospira	IL-9	Lachnospira-13-HODE+blood+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	HC
Lachnospira	IL-9	Lachnospira+GCA+stool-L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	HC
Lachnospira	IL-9	Lachnospira+16:0/22:6-PE+blood-L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	HC
Lachnospira	IL-9	Lachnospira-Intestinal immune network for IgA production+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	HC
Lachnospira	IL-9	Lachnospira+18:0/22:6-PE+blood-L-Glutamine+blood-IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	HC
Lachnospira	IL-9	Lachnospira-24:0+blood+d18:1-20:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	HC
Lachnospira	IL-9	Lachnospira-Herpes simplex virus 1 infection+d18:1-20:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.279	0.906	no	no	no	no	no	no	HC
isobutyric acid C4+blood	IL-9	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood-IL-9	Indirect	serum_scfa	serum_cytokines	0.0151	0.906	up	up	no	no	no	no	HC
GCDCA+stool	IL-9	GCDCA+stool+18:0/20:5-PC+blood+L-Lysine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.0471	0.906	no	dn	no	no	no	no	HC
GCDCA+stool	IL-9	GCDCA+stool-9-HODE+blood-L-Ornithine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.0471	0.906	no	dn	no	no	no	no	HC
GCDCA+stool	IL-9	GCDCA+stool-9-HODE+blood-L-Asparagine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.0471	0.906	no	dn	no	no	no	no	HC
GCDCA+stool	IL-9	GCDCA+stool+18:0/20:5-PC+blood+Cystine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.0471	0.906	no	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-9	5-Hydroxytryptamine+stool+GCA+stool-L-Methionine+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.906	dn	dn	no	no	no	no	HC
Odoribacter	IL-9	Odoribacter-18:0/20:5-PC+blood+Cystine+blood-IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	HC
Odoribacter	IL-9	Odoribacter-Phospholipase D signaling pathway+Cystine+blood-IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	HC
Odoribacter	IL-9	Odoribacter-Endocrine resistance+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	HC
Odoribacter	IL-9	Odoribacter-Gap junction+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	HC
Odoribacter	IL-9	Odoribacter-Long-term depression+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	HC
Odoribacter	IL-9	Odoribacter-Pancreatic secretion+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	HC
Odoribacter	IL-9	Odoribacter-Aldosterone synthesis and secretion+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	HC
Odoribacter	IL-9	Odoribacter-Cushing syndrome+Mineral absorption-IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	HC
Odoribacter	IL-9	Odoribacter-Long-term depression-d18:1-20:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	HC
Odoribacter	IL-9	Odoribacter-18:0/20:5-PC+blood+L-Lysine+blood-IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	HC
Odoribacter	IL-9	Odoribacter-Phospholipase D signaling pathway+L-Lysine+blood-IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	HC
Odoribacter	IL-9	Odoribacter-Endocrine resistance+Necroptosis-IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	HC
Odoribacter	IL-9	Odoribacter+Inflammatory bowel disease+24:1+blood-IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	HC
Odoribacter	IL-9	Odoribacter-Phospholipase D signaling pathway+L-Glutamic acid+blood-IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	HC
Odoribacter	IL-9	Odoribacter-Phospholipase D signaling pathway+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.798	0.906	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-9	Isobutyric acid+stool+Phenylacetic acid+stool+d18:1-20:1-SM+blood-L-Alanine+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.408	0.906	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-9	Isobutyric acid+stool+Isovaleric acid+stool-nutriCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_scfa	serum_cytokines	0.408	0.906	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-9	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-Cystine+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.408	0.906	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-9	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Asparagine+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.408	0.906	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-9	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Ornithine+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.408	0.906	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-9	Isobutyric acid+stool+Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Glutamine+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.408	0.906	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-9	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/20:4-PI+blood-L-Glutamine+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.408	0.906	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-9	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-L-Glutamine+blood-IL-9	Indirect	stool_scfa	serum_cytokines	0.408	0.906	no	no	no	no	no	no	HC
Kynurenic acid+stool	IL-9	Kynurenic acid+stool-nutriCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.037	0.906	dn	dn	no	no	no	no	HC
Kynurenic acid+stool	IL-9	Kynurenic acid+stool+T-¦Á-MCA+stool-TLCA+stool+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.037	0.906	dn	dn	no	no	no	no	HC
Eggerthella	IL-9	Eggerthella+Clostridium+IL-9	Indirect	Genus	serum_cytokines	0.912	0.906	no	no	no	no	no	no	HC
Anaerotruncus	IL-9	Anaerotruncus-Gemmiger-Cysteine+blood+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.904	0.906	no	no	no	no	no	no	HC
Anaerotruncus	IL-9	Anaerotruncus-Gemmiger+GLCA+blood+L-Glutamine+blood-IL-9	Indirect	Genus	serum_cytokines	0.904	0.906	no	no	no	no	no	no	HC
Anaerotruncus	IL-9	Anaerotruncus-Gemmiger-Cysteine+blood+L-Lysine+blood-IL-9	Indirect	Genus	serum_cytokines	0.904	0.906	no	no	no	no	no	no	HC
Anaerotruncus	IL-9	Anaerotruncus-Gemmiger-L-Phenylalanine+stool+18:1/18:1-PE+blood+IL-9	Indirect	Genus	serum_cytokines	0.904	0.906	no	no	no	no	no	no	HC
Anaerotruncus	IL-9	Anaerotruncus-Gemmiger-L-Tyrosine+stool+18:1/18:1-PE+blood+IL-9	Indirect	Genus	serum_cytokines	0.904	0.906	no	no	no	no	no	no	HC
Anaerotruncus	IL-9	Anaerotruncus-Gemmiger-L-Tryptophan+stool+18:1/18:1-PE+blood+IL-9	Indirect	Genus	serum_cytokines	0.904	0.906	no	no	no	no	no	no	HC
Anaerostipes	IL-9	Anaerostipes-Th1 and Th2 cell differentiation+L-Glutamine+blood-IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	HC
Anaerostipes	IL-9	Anaerostipes-Th17 cell differentiation+L-Glutamine+blood-IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	HC
Anaerostipes	IL-9	Anaerostipes+Human cytomegalovirus infection+d18:1-20:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	HC
Anaerostipes	IL-9	Anaerostipes+Human T-cell leukemia virus 1 infection+d18:1-20:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	HC
Anaerostipes	IL-9	Anaerostipes-Inflammatory bowel disease+24:1+blood-IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	HC
Anaerostipes	IL-9	Anaerostipes+Human T-cell leukemia virus 1 infection+d18:1-22:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.568	0.906	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-9	Isovaleric acid+stool-nutriCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_scfa	serum_cytokines	0.343	0.906	no	no	no	no	no	no	HC
Paraprevotella	IL-9	Paraprevotella+d18:1-20:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.118	0.906	no	no	no	no	no	no	HC
iso-LCA+blood	IL-9	"iso-LCA+blood+L-Proline+blood-MUFA+blood+n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine-Eotaxin-IL-9"	Indirect	serum_bileacids	serum_cytokines	0.507	0.906	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IL-9	¦Ø-MCA+stool-Butyric acid+stool-d18:1-22:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.919	0.906	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-14:0/18:2-PC+blood-Cystine+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool+d18:1-20:1-SM+blood-L-Alanine+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Asparagine+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Glutamine+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-16:0/20:4-PI+blood-L-Glutamine+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-16:0/18:2-PI+blood-L-Glutamine+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-9	Phenylacetic acid+stool-14:0/18:2-PC+blood-L-Ornithine+blood-IL-9	Indirect	stool_cometabolism	serum_cytokines	0.785	0.906	no	no	no	no	no	no	HC
Gemmiger	IL-9	Gemmiger-Cysteine+blood+L-Methionine+blood-IL-9	Indirect	Genus	serum_cytokines	0.595	0.906	no	no	no	no	no	no	HC
Gemmiger	IL-9	Gemmiger+GLCA+blood+L-Glutamine+blood-IL-9	Indirect	Genus	serum_cytokines	0.595	0.906	no	no	no	no	no	no	HC
Gemmiger	IL-9	Gemmiger-Cysteine+blood+L-Lysine+blood-IL-9	Indirect	Genus	serum_cytokines	0.595	0.906	no	no	no	no	no	no	HC
Gemmiger	IL-9	Gemmiger-L-Phenylalanine+stool+18:1/18:1-PE+blood+IL-9	Indirect	Genus	serum_cytokines	0.595	0.906	no	no	no	no	no	no	HC
Gemmiger	IL-9	Gemmiger-L-Tyrosine+stool+18:1/18:1-PE+blood+IL-9	Indirect	Genus	serum_cytokines	0.595	0.906	no	no	no	no	no	no	HC
Gemmiger	IL-9	Gemmiger-L-Tryptophan+stool+18:1/18:1-PE+blood+IL-9	Indirect	Genus	serum_cytokines	0.595	0.906	no	no	no	no	no	no	HC
GDCA+stool	IL-9	GDCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.656	0.906	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-9	L-Tyrosine+stool+18:1/18:1-PE+blood+IL-9	Indirect	stool_cometabolism	serum_cytokines	0.44	0.906	no	no	no	no	no	no	HC
CDCA+stool	IL-9	CDCA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.663	0.906	no	no	no	no	no	no	HC
CDCA+stool	IL-9	CDCA+stool+nutriCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.663	0.906	no	no	no	no	no	no	HC
CDCA+stool	IL-9	CDCA+stool+HCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.663	0.906	no	no	no	no	no	no	HC
CDCA+stool	IL-9	CDCA+stool+GCA+stool-L-Methionine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.663	0.906	no	no	no	no	no	no	HC
CA+stool	IL-9	CA+stool-T-¦Á-MCA+stool-TLCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.827	0.906	no	no	no	no	no	no	HC
CA+stool	IL-9	CA+stool-18:1/16:0-PC+blood-18:1/18:1-PE+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.827	0.906	no	no	no	no	no	no	HC
CA+stool	IL-9	CA+stool+nutriCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.827	0.906	no	no	no	no	no	no	HC
CA+stool	IL-9	CA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.827	0.906	no	no	no	no	no	no	HC
CA+stool	IL-9	CA+stool+GDCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.827	0.906	no	no	no	no	no	no	HC
CA+stool	IL-9	CA+stool+HCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.827	0.906	no	no	no	no	no	no	HC
CA+stool	IL-9	CA+stool+GCA+stool-L-Methionine+blood-IL-9	Indirect	stool_bileacids	serum_cytokines	0.827	0.906	no	no	no	no	no	no	HC
HDCA+blood	IL-9	HDCA+blood+L-Asparagine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.483	0.906	no	no	no	no	no	no	HC
TLCA+stool	IL-9	TLCA+stool+IL-9	Direct	stool_bileacids	serum_cytokines	0.243	0.906	no	no	no	no	no	no	HC
UDCA+stool	IL-9	UDCA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.266	0.906	no	no	no	no	no	no	HC
nutriCA+stool	IL-9	nutriCA+stool+d18:1-20:0-SM+blood+IL-9	Indirect	stool_bileacids	serum_cytokines	0.481	0.906	no	no	no	no	no	no	HC
acetic acid C2+blood	IL-9	acetic acid C2+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood-IL-9	Indirect	serum_scfa	serum_cytokines	0.000193	0.906	up	dn	no	no	no	no	HC
acetic acid C2+blood	IL-9	acetic acid C2+blood+heptanoic acid C7+blood+L-Asparagine+blood-IL-9	Indirect	serum_scfa	serum_cytokines	0.000193	0.906	up	dn	no	no	no	no	HC
acetic acid C2+blood	IL-9	acetic acid C2+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-IL-9	Indirect	serum_scfa	serum_cytokines	0.000193	0.906	up	dn	no	no	no	no	HC
Clostridium	IL-9	Clostridium+IL-9	Direct	Genus	serum_cytokines	0.925	0.906	no	no	no	no	no	no	HC
T-¦Á-MCA+stool	IL-9	T-¦Á-MCA+stool-TLCA+stool+IL-9	Indirect	stool_bileacids	serum_cytokines	0.48	0.906	no	no	no	no	no	no	HC
12-ketoDCA+blood	IL-9	12-ketoDCA+blood+16:0/16:1-PI+blood-L-Lysine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.517	0.906	no	no	no	no	no	no	HC
12-ketoDCA+blood	IL-9	12-ketoDCA+blood-DPA+blood-L-Glutamine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.517	0.906	no	no	no	no	no	no	HC
12-ketoDCA+blood	IL-9	12-ketoDCA+blood+14:0/16:0-PC+blood-L-Asparagine+blood-IL-9	Indirect	serum_bileacids	serum_cytokines	0.517	0.906	no	no	no	no	no	no	HC
Butyricicoccus	IL-9	Butyricicoccus+d18:1-22:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.852	0.906	no	no	no	no	no	no	HC
Wautersiella	IL-9	Wautersiella+Butyricicoccus+d18:1-22:0-SM+blood+IL-9	Indirect	Genus	serum_cytokines	0.289	0.906	no	no	no	no	no	no	HC
Blautia	Leptin	Blautia+P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	1.36E-05	0.706	up	dn	dn	no	no	no	HC
Blautia	Leptin	Blautia+16:0/20:5-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	1.36E-05	0.706	up	dn	dn	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-Phosphatidylinositol signaling system+Cardiac muscle contraction-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Biosynthesis of amino acids-Cardiac muscle contraction-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-RNA degradation+Cardiac muscle contraction-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Carbon metabolism-Cardiac muscle contraction-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Glycolysis / Gluconeogenesis-Cardiac muscle contraction-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-mRNA surveillance pathway+Cardiac muscle contraction-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+16:1/18:2-PG+blood-20:5n3+blood+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Glycolysis / Gluconeogenesis-Oxidative phosphorylation-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+16:1/18:2-PG+blood+Betaine+blood-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-Phosphatidylinositol signaling system+Alzheimer disease-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Biosynthesis of amino acids-Alzheimer disease-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-RNA degradation+Alzheimer disease-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Carbon metabolism-Alzheimer disease-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Glycolysis / Gluconeogenesis-Alzheimer disease-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-mRNA surveillance pathway+Alzheimer disease-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+16:0/18:1-PC+blood+Creatinine+blood-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Glycolysis / Gluconeogenesis-Creatinine+blood-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-Phosphatidylinositol signaling system+Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Biosynthesis of amino acids-Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-RNA degradation+Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-Colorectal cancer+Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Carbon metabolism-Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Glycolysis / Gluconeogenesis-Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-Pathways in cancer+Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-mRNA surveillance pathway+Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+16:0/18:1-PC+blood+n6/n3+blood-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+16:1/18:2-PG+blood+n6/n3+blood-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+18:1/18:2-PG+blood+n6/n3+blood-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-Phosphatidylinositol signaling system-Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Biosynthesis of amino acids+Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-RNA degradation-Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Carbon metabolism+Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-mRNA surveillance pathway-Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Biosynthesis of amino acids+16:0/18:3-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Carbon metabolism+16:0/18:3-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-Phosphatidylinositol signaling system+Thermogenesis-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Biosynthesis of amino acids-Thermogenesis-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-RNA degradation+Thermogenesis-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Carbon metabolism-Thermogenesis-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Glycolysis / Gluconeogenesis-Thermogenesis-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-mRNA surveillance pathway+Thermogenesis-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Biosynthesis of amino acids+CDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-mRNA surveillance pathway-CDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Biosynthesis of amino acids-iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-Phosphatidylinositol signaling system+Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Biosynthesis of amino acids-Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-RNA degradation+Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Carbon metabolism-Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Glycolysis / Gluconeogenesis-Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-mRNA surveillance pathway+Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Biosynthesis of amino acids+GCA+stool+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-RNA degradation-GCA+stool+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-mRNA surveillance pathway-GCA+stool+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Biosynthesis of amino acids+P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Carbon metabolism+P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-Phosphatidylinositol signaling system+Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Biosynthesis of amino acids-Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-RNA degradation+Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Carbon metabolism-Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides+Glycolysis / Gluconeogenesis-Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Parabacteroides	Leptin	Parabacteroides-mRNA surveillance pathway+Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	4.19E-05	0.706	no	up	up	no	no	no	HC
Dorea	Leptin	Dorea-iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	HC
Dorea	Leptin	Dorea+16:0/18:3-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	HC
Dorea	Leptin	Dorea+CDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.00362	0.706	up	no	dn	no	no	no	HC
Faecalibacterium	Leptin	Faecalibacterium+4-hydroxybenzoic acid+stool-20:5n3+blood+Leptin	Indirect	Genus	DM-associated hormones	0.0039	0.706	no	dn	dn	no	no	no	HC
Faecalibacterium	Leptin	Faecalibacterium+Butyric acid+stool-L-Phenylalanine+stool-Leptin	Indirect	Genus	DM-associated hormones	0.0039	0.706	no	dn	dn	no	no	no	HC
Faecalibacterium	Leptin	Faecalibacterium-Staphylococcus aureus infection-Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	0.0039	0.706	no	dn	dn	no	no	no	HC
TUDCA+blood	Leptin	TUDCA+blood+P-hydroxyhippuric acid+urine+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.0282	0.706	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	Leptin	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	serum_scfa	DM-associated hormones	0.0458	0.706	no	no	dn	no	no	no	HC
Bacteroides	Leptin	Bacteroides+CDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.000267	0.706	dn	dn	up	no	no	no	HC
Bacteroides	Leptin	Bacteroides+P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	0.000267	0.706	dn	dn	up	no	no	no	HC
Bacteroides	Leptin	Bacteroides-Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	0.000267	0.706	dn	dn	up	no	no	no	HC
Bacteroides	Leptin	Bacteroides-iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.000267	0.706	dn	dn	up	no	no	no	HC
Bacteroides	Leptin	Bacteroides-Thermogenesis-Leptin	Indirect	Genus	DM-associated hormones	0.000267	0.706	dn	dn	up	no	no	no	HC
Propionic acid+stool	Leptin	Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.706	dn	no	up	no	no	no	HC
Propionic acid+stool	Leptin	Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.706	dn	no	up	no	no	no	HC
Propionic acid+stool	Leptin	Propionic acid+stool+iso-LCA+blood-n3+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.706	dn	no	up	no	no	no	HC
Propionic acid+stool	Leptin	Propionic acid+stool+16:0/18:2-PI+blood-18:1-LPC+blood-Leptin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.706	dn	no	up	no	no	no	HC
Propionic acid+stool	Leptin	Propionic acid+stool-18:0/20:5-PC+blood+18:0/22:6-PC+blood+Leptin	Indirect	stool_scfa	DM-associated hormones	0.0436	0.706	dn	no	up	no	no	no	HC
[Ruminococcus]	Leptin	[Ruminococcus]+16:0/18:3-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.0679	0.706	no	no	dn	no	no	no	HC
[Ruminococcus]	Leptin	[Ruminococcus]-18:0/20:4-PI+blood-Leptin	Indirect	Genus	DM-associated hormones	0.0679	0.706	no	no	dn	no	no	no	HC
[Ruminococcus]	Leptin	[Ruminococcus]-Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.0679	0.706	no	no	dn	no	no	no	HC
GUDCA+blood	Leptin	GUDCA+blood-iso-DCA+blood+n6/n3+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.706	no	no	dn	no	no	no	HC
GUDCA+blood	Leptin	GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.0766	0.706	no	no	dn	no	no	no	HC
Acetic acid+stool	Leptin	Acetic acid+stool-Phenylacetic acid+stool-Leptin	Indirect	stool_scfa	DM-associated hormones	0.0656	0.706	dn	no	no	no	no	no	HC
Alistipes	Leptin	Alistipes-Leptin	Direct	Genus	DM-associated hormones	0.0114	0.706	no	up	no	no	no	no	HC
Butyricimonas	Leptin	Butyricimonas-Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	HC
Butyricimonas	Leptin	Butyricimonas+Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	0.17	0.706	no	no	no	no	no	no	HC
Collinsella	Leptin	Collinsella-18:1-LPC+blood-Leptin	Indirect	Genus	DM-associated hormones	0.128	0.706	no	no	no	no	no	no	HC
iso-DCA+stool	Leptin	iso-DCA+stool+iso-LCA+stool-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.706	no	no	no	no	no	no	HC
LCA+stool	Leptin	"LCA+stool+9,10-EPOME+blood-Betaine+blood-Leptin"	Indirect	stool_bileacids	DM-associated hormones	0.314	0.706	no	no	no	no	no	no	HC
LCA+stool	Leptin	LCA+stool-nutriCA+stool+16:0/18:3-PC+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.706	no	no	no	no	no	no	HC
LCA+stool	Leptin	LCA+stool+16:0/18:1-PC+blood+Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.706	no	no	no	no	no	no	HC
LCA+stool	Leptin	LCA+stool+18:0/16:0-PC+blood+Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.706	no	no	no	no	no	no	HC
LCA+stool	Leptin	LCA+stool-TCA+stool-Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.706	no	no	no	no	no	no	HC
LCA+stool	Leptin	LCA+stool+16:0/18:1-PC+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.706	no	no	no	no	no	no	HC
LCA+stool	Leptin	LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.314	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Ribosome+Cardiac muscle contraction-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Wnt signaling pathway+Thermogenesis-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Ribosome+Thermogenesis-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Wnt signaling pathway+Alzheimer disease-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Ribosome+Alzheimer disease-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Wnt signaling pathway+Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Ribosome+Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia+Pertussis+16:0/18:3-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia+Pertussis+CDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Coronavirus disease - COVID-19-CDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Ribosome-CDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Wnt signaling pathway+iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia+Pertussis-iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia+Pertussis+n3+blood+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-iso-LCA+blood-n3+blood+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-LCA+blood-n3+blood+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Coronavirus disease - COVID-19-n3+blood+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Ribosome-n3+blood+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Wnt signaling pathway-Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia+Pertussis+Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Ribosome-Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Wnt signaling pathway+Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Ribosome+Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Acetic acid+stool-Phenylacetic acid+stool-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-LCA+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Coronavirus disease - COVID-19-GCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Ribosome-GCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Wnt signaling pathway+Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Coronavirus disease - COVID-19+Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia-Ribosome+Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Akkermansia	Leptin	Akkermansia+Systemic lupus erythematosus-Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	0.23	0.706	no	no	no	no	no	no	HC
Bifidobacterium	Leptin	Bifidobacterium-Intestinal immune network for IgA production-GCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	HC
Bifidobacterium	Leptin	Bifidobacterium-12-ketoDCA+blood-18:1-LPC+blood-Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	HC
Bifidobacterium	Leptin	Bifidobacterium-L-Ornithine+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	HC
Bifidobacterium	Leptin	Bifidobacterium+13-HODE+blood+n6/n3+blood-Leptin	Indirect	Genus	DM-associated hormones	0.105	0.706	no	dn	no	no	no	no	HC
Ruminococcus	Leptin	Ruminococcus+Thermogenesis-Leptin	Indirect	Genus	DM-associated hormones	0.335	0.706	no	no	no	no	no	no	HC
Ruminococcus	Leptin	Ruminococcus-P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	0.335	0.706	no	no	no	no	no	no	HC
GCDCA+blood	Leptin	GCDCA+blood-iso-DCA+blood+n6/n3+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.706	no	no	no	no	no	no	HC
GCDCA+blood	Leptin	GCDCA+blood-MUFA%+blood+n6/n3+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.31	0.706	no	no	no	no	no	no	HC
[Prevotella]	Leptin	[Prevotella]-18:0/22:6-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.367	0.706	no	no	no	no	no	no	HC
ACA+blood	Leptin	ACA+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.338	0.706	no	no	no	no	no	no	HC
DCA+stool	Leptin	DCA+stool-L-Phenylalanine+stool-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	HC
DCA+stool	Leptin	DCA+stool+iso-LCA+stool-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.195	0.706	no	no	no	no	no	no	HC
Butyric acid+stool	Leptin	Butyric acid+stool-L-Phenylalanine+stool-Leptin	Indirect	stool_scfa	DM-associated hormones	0.102	0.706	dn	no	no	no	no	no	HC
4-hydroxybenzoic acid+stool	Leptin	4-hydroxybenzoic acid+stool-20:5n3+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.0536	0.706	no	dn	no	no	no	no	HC
GCA+blood	Leptin	GCA+blood+TCA+blood+P-hydroxyhippuric acid+urine+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.706	no	no	no	no	no	no	HC
GCA+blood	Leptin	GCA+blood-iso-DCA+blood+n6/n3+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.16	0.706	no	no	no	no	no	no	HC
ACA+stool	Leptin	ACA+stool+MUFA%+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.706	no	no	no	no	no	no	HC
ACA+stool	Leptin	ACA+stool-18:0/18:2-PI+blood-20:5n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.706	no	no	no	no	no	no	HC
ACA+stool	Leptin	ACA+stool-Acetic acid+stool-Phenylacetic acid+stool-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.417	0.706	no	no	no	no	no	no	HC
CDCA+blood	Leptin	CDCA+blood-Creatinine+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.506	0.706	no	no	no	no	no	no	HC
capric acid C6+blood	Leptin	capric acid C6+blood-Cystine+blood+MUFA%+blood+n6/n3+blood-Leptin	Indirect	serum_scfa	DM-associated hormones	0.433	0.706	no	no	no	no	no	no	HC
capric acid C6+blood	Leptin	capric acid C6+blood-Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	serum_scfa	DM-associated hormones	0.433	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-24:1+blood+Creatinine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-16:1/16:0-PC+blood+Creatinine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella+18:0/18:1-PE+blood-Creatinine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella+12-ketoDCA+blood-18:1-LPC+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-B cell receptor signaling pathway+18:1-LPC+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-IL-17 signaling pathway+CDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+CDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-Lysosome+CDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-20:3/18:0-PC+blood+n3+blood+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-IL-17 signaling pathway-iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-Epithelial cell signaling in Helicobacter pylori infection-iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+GCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-18:1/18:1-PC+blood+n6/n3+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella+18:0/18:1-PE+blood-n6/n3+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-iso-DCA+blood+n6/n3+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-MUFA%+blood+n6/n3+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-18:1/18:1-PC+blood-22:6n3+blood+Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-18:0/20:4-PC+blood+18:0/20:4-PI+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-16:1/16:1-PC+blood+18:0/20:4-PI+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-L-Tryptophan+stool+Phenylacetic acid+stool-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
Prevotella	Leptin	Prevotella-18:2/20:4-PC+blood-Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.287	0.706	no	no	no	no	no	no	HC
TCA+blood	Leptin	TCA+blood+P-hydroxyhippuric acid+urine+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.339	0.706	no	no	no	no	no	no	HC
iso-DCA+blood	Leptin	iso-DCA+blood+n6/n3+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.38	0.706	no	no	no	no	no	no	HC
HCA+stool	Leptin	HCA+stool-iso-LCA+stool-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.706	no	no	no	no	no	no	HC
HCA+stool	Leptin	HCA+stool+16:0/18:3-PC+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.155	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-Neurotrophin signaling pathway+Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-Neurotrophin signaling pathway+Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-Neurotrophin signaling pathway+Alzheimer disease-Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-Neurotrophin signaling pathway+18:1-LPC+blood-Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-RNA transport-Creatinine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-RNA transport-L-Phenylalanine+stool-Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-Transcriptional misregulation in cancer-iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-RIG-I-like receptor signaling pathway-iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-NF-kappa B signaling pathway-iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-3-(3-Hydroxyphenyl)propanoic acid+stool+14:0/18:2-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-RNA transport+14:0/18:2-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/22:6-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-3-(3-Hydroxyphenyl)propanoic acid+stool+20:2/18:0-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-L-Homocystine+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-3-(3-Hydroxyphenyl)propanoic acid+stool-Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-Proteoglycans in cancer-18:0/20:4-PI+blood-Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-Insulin resistance+Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
Roseburia	Leptin	Roseburia-Neurotrophin signaling pathway+Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	0.495	0.706	no	no	no	no	no	no	HC
12-ketoDCA+stool	Leptin	12-ketoDCA+stool-CDCA+stool+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.505	0.706	no	no	no	no	no	no	HC
GLCA+blood	Leptin	GLCA+blood+LCA+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.706	no	no	no	no	no	no	HC
GLCA+blood	Leptin	GLCA+blood+LCA+blood-n3+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.706	no	no	no	no	no	no	HC
GLCA+blood	Leptin	GLCA+blood+iso-LCA+blood-n3+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.319	0.706	no	no	no	no	no	no	HC
L-Tryptophan+stool	Leptin	L-Tryptophan+stool+Phenylacetic acid+stool-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.557	0.706	no	no	no	no	no	no	HC
CA+blood	Leptin	CA+blood+LCA+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.706	no	no	no	no	no	no	HC
CA+blood	Leptin	CA+blood+LCA+blood-n3+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.706	no	no	no	no	no	no	HC
CA+blood	Leptin	CA+blood+CDCA+blood-Creatinine+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.606	0.706	no	no	no	no	no	no	HC
GUDCA+stool	Leptin	GUDCA+stool+Phenylacetic acid+stool-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.0085	0.706	no	dn	no	no	no	no	HC
L-Phenylalanine+stool	Leptin	L-Phenylalanine+stool-Leptin	Direct	stool_cometabolism	DM-associated hormones	0.398	0.706	no	no	no	no	no	no	HC
butyric acid C4+blood	Leptin	butyric acid C4+blood+Cystine+blood+MUFA%+blood+n6/n3+blood-Leptin	Indirect	serum_scfa	DM-associated hormones	0.407	0.706	no	no	no	no	no	no	HC
butyric acid C4+blood	Leptin	butyric acid C4+blood+heptanoic acid C7+blood+lauric acid C12+blood+n6/n3+blood-Leptin	Indirect	serum_scfa	DM-associated hormones	0.407	0.706	no	no	no	no	no	no	HC
butyric acid C4+blood	Leptin	butyric acid C4+blood+iso-heptanoic acid C7+blood-L-Histidine+blood+n6/n3+blood-Leptin	Indirect	serum_scfa	DM-associated hormones	0.407	0.706	no	no	no	no	no	no	HC
butyric acid C4+blood	Leptin	butyric acid C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	serum_scfa	DM-associated hormones	0.407	0.706	no	no	no	no	no	no	HC
butyric acid C4+blood	Leptin	butyric acid C4+blood+Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	serum_scfa	DM-associated hormones	0.407	0.706	no	no	no	no	no	no	HC
GCA+stool	Leptin	GCA+stool+Leptin	Direct	stool_bileacids	DM-associated hormones	0.0809	0.706	no	no	no	no	no	no	HC
Coprococcus	Leptin	Coprococcus+Leptin	Direct	Genus	DM-associated hormones	0.612	0.706	no	no	no	no	no	no	HC
Oscillospira	Leptin	Oscillospira-P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	0.62	0.706	no	no	no	no	no	no	HC
Oscillospira	Leptin	Oscillospira+20:5n3+blood+Leptin	Indirect	Genus	DM-associated hormones	0.62	0.706	no	no	no	no	no	no	HC
Oscillospira	Leptin	Oscillospira+iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.62	0.706	no	no	no	no	no	no	HC
HCA+blood	Leptin	HCA+blood-MUFA%+blood+n6/n3+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.544	0.706	no	no	no	no	no	no	HC
iso-LCA+stool	Leptin	iso-LCA+stool-Leptin	Direct	stool_bileacids	DM-associated hormones	0.72	0.706	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	Leptin	2-methyl-butyric acid m-C4+blood+20:1+blood-22:6n3+blood+Leptin	Indirect	serum_scfa	DM-associated hormones	0.262	0.706	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	Leptin	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+n6/n3+blood-Leptin	Indirect	serum_scfa	DM-associated hormones	0.262	0.706	no	no	no	no	no	no	HC
DCA+blood	Leptin	"DCA+blood-n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine+Leptin"	Indirect	serum_bileacids	DM-associated hormones	0.122	0.706	no	no	no	no	no	no	HC
DCA+blood	Leptin	DCA+blood+GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.706	no	no	no	no	no	no	HC
DCA+blood	Leptin	DCA+blood+GUDCA+blood-iso-DCA+blood+n6/n3+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.122	0.706	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	Leptin	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/22:6-PC+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.706	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	Leptin	3-(3-Hydroxyphenyl)propanoic acid+stool+14:0/18:2-PC+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.706	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	Leptin	3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.706	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	Leptin	3-(3-Hydroxyphenyl)propanoic acid+stool-Hypotaurine+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.706	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	Leptin	3-(3-Hydroxyphenyl)propanoic acid+stool+20:2/18:0-PC+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.33	0.706	no	no	no	no	no	no	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	Leptin	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine+Leptin"	Indirect	urine_cometabolism	DM-associated hormones	0.0125	0.706	up	up	no	no	no	no	HC
GLCA+stool	Leptin	GLCA+stool-iso-LCA+stool-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.617	0.706	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Leptin	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.706	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	Leptin	Indole-3-Acetic acid+stool+L-Phenylalanine+stool-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.304	0.706	no	no	no	no	no	no	HC
TCA+stool	Leptin	TCA+stool-Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.458	0.706	no	no	no	no	no	no	HC
HDCA+stool	Leptin	HDCA+stool+iso-LCA+stool-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	HC
HDCA+stool	Leptin	HDCA+stool-16:0/18:3-PC+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	HC
HDCA+stool	Leptin	HDCA+stool-n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.176	0.706	no	no	no	no	no	no	HC
Lachnospira	Leptin	Lachnospira+GCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	HC
Lachnospira	Leptin	Lachnospira-18:1-LPC+blood-Leptin	Indirect	Genus	DM-associated hormones	0.279	0.706	no	no	no	no	no	no	HC
isobutyric acid C4+blood	Leptin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Phenylalanine+blood+lauric acid C12+blood+n6/n3+blood-Leptin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.706	up	up	no	no	no	no	HC
isobutyric acid C4+blood	Leptin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+lauric acid C12+blood+n6/n3+blood-Leptin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.706	up	up	no	no	no	no	HC
isobutyric acid C4+blood	Leptin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Tryptophan+blood+lauric acid C12+blood+n6/n3+blood-Leptin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.706	up	up	no	no	no	no	HC
isobutyric acid C4+blood	Leptin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+MUFA%+blood+n6/n3+blood-Leptin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.706	up	up	no	no	no	no	HC
isobutyric acid C4+blood	Leptin	isobutyric acid C4+blood+L-Leucine+blood-MUFA+blood+MUFA%+blood+n6/n3+blood-Leptin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.706	up	up	no	no	no	no	HC
isobutyric acid C4+blood	Leptin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Tryptophan+blood+MUFA%+blood+n6/n3+blood-Leptin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.706	up	up	no	no	no	no	HC
isobutyric acid C4+blood	Leptin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.706	up	up	no	no	no	no	HC
isobutyric acid C4+blood	Leptin	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	serum_scfa	DM-associated hormones	0.0151	0.706	up	up	no	no	no	no	HC
GCDCA+stool	Leptin	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.706	no	dn	no	no	no	no	HC
GCDCA+stool	Leptin	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.706	no	dn	no	no	no	no	HC
GCDCA+stool	Leptin	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.0471	0.706	no	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	Leptin	5-Hydroxytryptamine+stool+GCA+stool+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.00862	0.706	dn	dn	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Endocrine resistance+Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Long-term depression+Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Pancreatic secretion+Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Aldosterone synthesis and secretion+Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Cushing syndrome+Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-18:0/20:5-PC+blood+18:0/22:6-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Endocrine resistance-CDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Cushing syndrome-CDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Long-term depression-P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Pancreatic secretion-P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Cushing syndrome+iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Endocrine resistance-16:0/18:3-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Long-term depression-16:0/18:3-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Cushing syndrome-16:0/18:3-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Endocrine resistance+Alzheimer disease-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Long-term depression+Alzheimer disease-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Pancreatic secretion+Alzheimer disease-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Aldosterone synthesis and secretion+Alzheimer disease-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Cushing syndrome+Alzheimer disease-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter+Inflammatory bowel disease-GCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Endocrine resistance+Thermogenesis-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter+Arginine and proline metabolism-Thermogenesis-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Endocrine resistance+Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Long-term depression+Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter+Arginine and proline metabolism-Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Pancreatic secretion+Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Cushing syndrome+Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Gap junction-18:0/20:4-PI+blood-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Morphine addiction+Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Long-term depression+Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Pancreatic secretion+Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Aldosterone synthesis and secretion+Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Odoribacter	Leptin	Odoribacter-Cushing syndrome+Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	0.798	0.706	no	no	no	no	no	no	HC
Isobutyric acid+stool	Leptin	Isobutyric acid+stool+Phenylacetic acid+stool-Leptin	Indirect	stool_scfa	DM-associated hormones	0.408	0.706	no	no	no	no	no	no	HC
Kynurenic acid+stool	Leptin	Kynurenic acid+stool-UDCA+stool+16:0/18:3-PC+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.706	dn	dn	no	no	no	no	HC
Kynurenic acid+stool	Leptin	Kynurenic acid+stool-nutriCA+stool+16:0/18:3-PC+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.037	0.706	dn	dn	no	no	no	no	HC
Eggerthella	Leptin	Eggerthella+Bacteroides+CDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.912	0.706	no	no	no	no	no	no	HC
Eggerthella	Leptin	Eggerthella+Clostridium+14:0/18:2-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.912	0.706	no	no	no	no	no	no	HC
Eggerthella	Leptin	Eggerthella+Bacteroides-iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.912	0.706	no	no	no	no	no	no	HC
Eggerthella	Leptin	Eggerthella+Bacteroides-Thermogenesis-Leptin	Indirect	Genus	DM-associated hormones	0.912	0.706	no	no	no	no	no	no	HC
Eggerthella	Leptin	Eggerthella-Gemmiger-L-Phenylalanine+stool-Leptin	Indirect	Genus	DM-associated hormones	0.912	0.706	no	no	no	no	no	no	HC
Eggerthella	Leptin	Eggerthella+Clostridium+L-Phenylalanine+stool-Leptin	Indirect	Genus	DM-associated hormones	0.912	0.706	no	no	no	no	no	no	HC
Eggerthella	Leptin	Eggerthella+Clostridium-Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.912	0.706	no	no	no	no	no	no	HC
Eggerthella	Leptin	Eggerthella+Clostridium+18:0/22:6-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.912	0.706	no	no	no	no	no	no	HC
Eggerthella	Leptin	Eggerthella+Clostridium+20:2/18:0-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.912	0.706	no	no	no	no	no	no	HC
Eggerthella	Leptin	Eggerthella+Clostridium+P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	0.912	0.706	no	no	no	no	no	no	HC
Eggerthella	Leptin	Eggerthella+Bacteroides+P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	0.912	0.706	no	no	no	no	no	no	HC
Eggerthella	Leptin	Eggerthella+Bacteroides-Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	0.912	0.706	no	no	no	no	no	no	HC
Anaerotruncus	Leptin	Anaerotruncus-Gemmiger-L-Phenylalanine+stool-Leptin	Indirect	Genus	DM-associated hormones	0.904	0.706	no	no	no	no	no	no	HC
Anaerostipes	Leptin	Anaerostipes-18:1-LPC+blood-Leptin	Indirect	Genus	DM-associated hormones	0.568	0.706	no	no	no	no	no	no	HC
Isovaleric acid+stool	Leptin	Isovaleric acid+stool+Phenylacetic acid+stool-Leptin	Indirect	stool_scfa	DM-associated hormones	0.343	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Glycolysis / Gluconeogenesis-Creatinine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Carbon metabolism+Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella-p53 signaling pathway-Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Salmonella infection+Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Salmonella infection+CDCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Carbon metabolism+P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella-L-Homocystine+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella-Chemical carcinogenesis - receptor activation-P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Glycolysis / Gluconeogenesis-Oxidative phosphorylation-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Carbon metabolism-Thermogenesis-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Glycolysis / Gluconeogenesis-Thermogenesis-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella-Insulin resistance+Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Carbon metabolism-Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Glycolysis / Gluconeogenesis-Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella-Relaxin signaling pathway+Huntington disease-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Carbon metabolism+16:0/18:3-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	"Paraprevotella-Growth hormone synthesis, secretion and action-16:0/18:3-PC+blood+Leptin"	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella-Longevity regulating pathway-16:0/18:3-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Rheumatoid arthritis+16:0/18:3-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella-Chemical carcinogenesis - receptor activation-16:0/18:3-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Carbon metabolism-Alzheimer disease-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Glycolysis / Gluconeogenesis-Alzheimer disease-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella-Relaxin signaling pathway+Alzheimer disease-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Carbon metabolism-Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella-GnRH signaling pathway+Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Glycolysis / Gluconeogenesis-Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella-Relaxin signaling pathway+Amyotrophic lateral sclerosis-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+13-HODE+blood+n6/n3+blood-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Carbon metabolism-Cardiac muscle contraction-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Glycolysis / Gluconeogenesis-Cardiac muscle contraction-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella-GnRH signaling pathway+18:0/22:6-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Carbon metabolism-Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella+Glycolysis / Gluconeogenesis-Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella-Chemical carcinogenesis - receptor activation+Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Paraprevotella	Leptin	Paraprevotella-Relaxin signaling pathway+Diabetic cardiomyopathy-Leptin	Indirect	Genus	DM-associated hormones	0.118	0.706	no	no	no	no	no	no	HC
Homovanillic acid+urine	Leptin	Homovanillic acid+urine+P-hydroxyhippuric acid+urine+Leptin	Indirect	urine_cometabolism	DM-associated hormones	0.45	0.706	no	no	no	no	no	no	HC
iso-LCA+blood	Leptin	iso-LCA+blood-n3+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.507	0.706	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Leptin	¦Ø-MCA+stool-Butyric acid+stool-L-Phenylalanine+stool-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.706	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Leptin	¦Ø-MCA+stool-iso-DCA+stool+iso-LCA+stool-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.706	no	no	no	no	no	no	HC
¦Ø-MCA+stool	Leptin	¦Ø-MCA+stool-Acetic acid+stool-Phenylacetic acid+stool-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.919	0.706	no	no	no	no	no	no	HC
Phenylacetic acid+stool	Leptin	Phenylacetic acid+stool-Leptin	Direct	stool_cometabolism	DM-associated hormones	0.785	0.706	no	no	no	no	no	no	HC
Gemmiger	Leptin	Gemmiger-L-Phenylalanine+stool-Leptin	Indirect	Genus	DM-associated hormones	0.595	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+16:1/18:2-PG+blood-20:5n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+16:1/16:1-PC+blood+18:0/20:4-PI+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+18:0/20:4-PC+blood+18:0/20:4-PI+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood-18:0-LPE+blood+22:6n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+16:0/20:4-PC+blood-22:6n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+18:1/18:1-PC+blood-22:6n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+18:1/18:1-PC+blood-22:6n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood-16:0/20:4-PI+blood+22:6n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+16:0/22:6-PC+blood+22:6n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+20:1/20:4-PC+blood+22:6n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+20:1/20:4-PC+blood+22:6n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+20:3/16:0-PC+blood-22:6n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+20:3/16:0-PC+blood-22:6n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+16:0/22:6-PC+blood+n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+20:1/20:4-PC+blood+n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+20:1/20:4-PC+blood+n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-Propionic acid+stool+iso-LCA+blood-n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+20:5/18:0-PC+blood+n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+20:5/18:0-PC+blood+n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+20:3/16:0-PC+blood-n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+20:3/16:0-PC+blood-n3+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+16:0/22:6-PC+blood+18:0/22:6-PC+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+18:0/20:5-PC+blood+18:0/22:6-PC+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-Propionic acid+stool-18:0/20:5-PC+blood+18:0/22:6-PC+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood-16:0/20:4-PI+blood-18:1-LPC+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-18:1-LPC+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+16:0/22:6-PC+blood-Hypotaurine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+20:1/20:4-PC+blood-Hypotaurine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+20:1/20:4-PC+blood-Hypotaurine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+20:5/18:0-PC+blood-Hypotaurine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+20:5/18:0-PC+blood-Hypotaurine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood-18:3n6+blood+20:2/18:0-PC+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood-18:3n6+blood+20:2/18:0-PC+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+16:1/18:2-PG+blood+Betaine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood-18:3n6+blood-Betaine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood-18:3n6+blood-Betaine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool+d18:1-16:0-SM+blood-TCA+blood+P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool+d18:0-16:0-SM+blood-TCA+blood+P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood-TUDCA+blood+P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood-TUDCA+blood+P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool+d18:1-20:0-SM+blood-L-Homocystine+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool+d18:1-20:0-SM+blood-L-Ornithine+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+ACA+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+ACA+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood-Homovanillic acid+urine+P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood-Homovanillic acid+urine+P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool+d18:1-20:0-SM+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+16:0/20:4-PC+blood+Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood-16:0/20:4-PI+blood-Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood-18:3/16:0-PE+blood-Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood-18:3/16:0-PE+blood-Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+16:1/16:0-PC+blood+Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+18:2/16:0-PC+blood+Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+18:2/16:0-PC+blood+Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood-18:0/18:1-PE+blood-Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood-18:0/18:0-PE+blood-Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood-18:3n6+blood-Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood-18:3n6+blood-Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+18:0/16:0-PC+blood+Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+20:3/16:0-PC+blood+Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+20:3/16:0-PC+blood+Creatinine+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+16:1/18:2-PG+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+16:0/20:4-PC+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+18:1/18:1-PC+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+18:1/18:1-PC+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood-16:0/20:4-PI+blood-n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+18:2/16:0-PC+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+18:2/16:0-PC+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood-18:0/18:1-PE+blood-n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+18:1/18:2-PG+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+18:1/18:2-PG+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood-18:0/18:0-PE+blood-n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool+d18:1-16:0-SM+blood+d18:1-18:1-SM+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool+d18:0-16:0-SM+blood+d18:1-18:1-SM+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+20:3/16:0-PC+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+20:3/16:0-PC+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool+d18:1-20:0-SM+blood+d18:1-20:1-SM+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool+d18:1-16:0-SM+blood+d18:1-20:1-SM+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool+d18:0-16:0-SM+blood+d18:1-20:1-SM+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+iso-DCA+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+iso-DCA+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+L-Histidine+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+L-Histidine+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+MUFA%+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+MUFA%+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-18:1/16:0-PC+blood+lauric acid C12+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
GDCA+stool	Leptin	GDCA+stool-16:0/18:2-PC+blood+lauric acid C12+blood+n6/n3+blood-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.656	0.706	no	no	no	no	no	no	HC
L-Tyrosine+stool	Leptin	L-Tyrosine+stool-12-ketoDCA+blood-18:1-LPC+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.706	no	no	no	no	no	no	HC
L-Tyrosine+stool	Leptin	L-Tyrosine+stool-18:3n6+blood+20:2/18:0-PC+blood+Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.706	no	no	no	no	no	no	HC
L-Tyrosine+stool	Leptin	L-Tyrosine+stool-18:3n6+blood-Creatinine+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.706	no	no	no	no	no	no	HC
L-Tyrosine+stool	Leptin	L-Tyrosine+stool-18:3n6+blood-Betaine+blood-Leptin	Indirect	stool_cometabolism	DM-associated hormones	0.44	0.706	no	no	no	no	no	no	HC
CDCA+stool	Leptin	CDCA+stool+Leptin	Direct	stool_bileacids	DM-associated hormones	0.663	0.706	no	no	no	no	no	no	HC
CA+stool	Leptin	CA+stool+16:0/18:3-PC+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.706	no	no	no	no	no	no	HC
CA+stool	Leptin	CA+stool+CDCA+stool+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.706	no	no	no	no	no	no	HC
CA+stool	Leptin	CA+stool+GCA+stool+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.706	no	no	no	no	no	no	HC
CA+stool	Leptin	CA+stool-iso-LCA+stool-Leptin	Indirect	stool_bileacids	DM-associated hormones	0.827	0.706	no	no	no	no	no	no	HC
HDCA+blood	Leptin	HDCA+blood+L-Histidine+blood+n6/n3+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.706	no	no	no	no	no	no	HC
HDCA+blood	Leptin	HDCA+blood+lauric acid C12+blood+n6/n3+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.483	0.706	no	no	no	no	no	no	HC
UDCA+stool	Leptin	UDCA+stool+16:0/18:3-PC+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.266	0.706	no	no	no	no	no	no	HC
LCA+blood	Leptin	LCA+blood-P-hydroxyhippuric acid+urine+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.884	0.706	no	no	no	no	no	no	HC
LCA+blood	Leptin	LCA+blood-n3+blood+Leptin	Indirect	serum_bileacids	DM-associated hormones	0.884	0.706	no	no	no	no	no	no	HC
nutriCA+stool	Leptin	nutriCA+stool+16:0/18:3-PC+blood+Leptin	Indirect	stool_bileacids	DM-associated hormones	0.481	0.706	no	no	no	no	no	no	HC
P-hydroxyhippuric acid+urine	Leptin	P-hydroxyhippuric acid+urine+Leptin	Direct	urine_cometabolism	DM-associated hormones	0.436	0.706	no	no	no	no	no	no	HC
acetic acid C2+blood	Leptin	acetic acid C2+blood+n3+blood+Leptin	Indirect	serum_scfa	DM-associated hormones	0.000193	0.706	up	dn	no	no	no	no	HC
Clostridium	Leptin	Clostridium+14:0/18:2-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	HC
Clostridium	Leptin	Clostridium+20:2/18:0-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	HC
Clostridium	Leptin	Clostridium+18:0/22:6-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	HC
Clostridium	Leptin	Clostridium+P-hydroxyhippuric acid+urine+Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	HC
Clostridium	Leptin	Clostridium-Hypotaurine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	HC
Clostridium	Leptin	Clostridium+L-Phenylalanine+stool-Leptin	Indirect	Genus	DM-associated hormones	0.925	0.706	no	no	no	no	no	no	HC
12-ketoDCA+blood	Leptin	12-ketoDCA+blood-18:1-LPC+blood-Leptin	Indirect	serum_bileacids	DM-associated hormones	0.517	0.706	no	no	no	no	no	no	HC
Butyricicoccus	Leptin	Butyricicoccus-18:2/16:0-PC+blood+Creatinine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.852	0.706	no	no	no	no	no	no	HC
Butyricicoccus	Leptin	Butyricicoccus-Rap1 signaling pathway+Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.852	0.706	no	no	no	no	no	no	HC
Butyricicoccus	Leptin	Butyricicoccus-Leukocyte transendothelial migration+Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.852	0.706	no	no	no	no	no	no	HC
Butyricicoccus	Leptin	Butyricicoccus-Leukocyte transendothelial migration+GCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.852	0.706	no	no	no	no	no	no	HC
Butyricicoccus	Leptin	Butyricicoccus+18:0/20:2-PC+blood+20:2/18:0-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.852	0.706	no	no	no	no	no	no	HC
Butyricicoccus	Leptin	Butyricicoccus-Thyroid hormone signaling pathway+iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.852	0.706	no	no	no	no	no	no	HC
Butyricicoccus	Leptin	Butyricicoccus-Hepatocellular carcinoma+iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.852	0.706	no	no	no	no	no	no	HC
Butyricicoccus	Leptin	Butyricicoccus-Platelet activation+iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.852	0.706	no	no	no	no	no	no	HC
Butyricicoccus	Leptin	Butyricicoccus-18:2/16:0-PC+blood+n6/n3+blood-Leptin	Indirect	Genus	DM-associated hormones	0.852	0.706	no	no	no	no	no	no	HC
Butyricicoccus	Leptin	Butyricicoccus-18:2-LPC+blood+n6/n3+blood-Leptin	Indirect	Genus	DM-associated hormones	0.852	0.706	no	no	no	no	no	no	HC
Butyricicoccus	Leptin	Butyricicoccus-18:2-LPC+blood-20:5n3+blood+Leptin	Indirect	Genus	DM-associated hormones	0.852	0.706	no	no	no	no	no	no	HC
Wautersiella	Leptin	Wautersiella+Butyricicoccus-18:2/16:0-PC+blood+Creatinine+blood-Leptin	Indirect	Genus	DM-associated hormones	0.289	0.706	no	no	no	no	no	no	HC
Wautersiella	Leptin	Wautersiella+Butyricicoccus-Rap1 signaling pathway+Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.289	0.706	no	no	no	no	no	no	HC
Wautersiella	Leptin	Wautersiella+Butyricicoccus-Leukocyte transendothelial migration+Human papillomavirus infection+Leptin	Indirect	Genus	DM-associated hormones	0.289	0.706	no	no	no	no	no	no	HC
Wautersiella	Leptin	Wautersiella+Butyricicoccus-Leukocyte transendothelial migration+GCA+stool+Leptin	Indirect	Genus	DM-associated hormones	0.289	0.706	no	no	no	no	no	no	HC
Wautersiella	Leptin	Wautersiella+Butyricicoccus+18:0/20:2-PC+blood+20:2/18:0-PC+blood+Leptin	Indirect	Genus	DM-associated hormones	0.289	0.706	no	no	no	no	no	no	HC
Wautersiella	Leptin	Wautersiella+Butyricicoccus-Thyroid hormone signaling pathway+iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.289	0.706	no	no	no	no	no	no	HC
Wautersiella	Leptin	Wautersiella+Butyricicoccus-Hepatocellular carcinoma+iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.289	0.706	no	no	no	no	no	no	HC
Wautersiella	Leptin	Wautersiella+Butyricicoccus-Platelet activation+iso-LCA+stool-Leptin	Indirect	Genus	DM-associated hormones	0.289	0.706	no	no	no	no	no	no	HC
Wautersiella	Leptin	Wautersiella+Butyricicoccus-18:2/16:0-PC+blood+n6/n3+blood-Leptin	Indirect	Genus	DM-associated hormones	0.289	0.706	no	no	no	no	no	no	HC
Wautersiella	Leptin	Wautersiella+Butyricicoccus-18:2-LPC+blood+n6/n3+blood-Leptin	Indirect	Genus	DM-associated hormones	0.289	0.706	no	no	no	no	no	no	HC
Wautersiella	Leptin	Wautersiella+Butyricicoccus-18:2-LPC+blood-20:5n3+blood+Leptin	Indirect	Genus	DM-associated hormones	0.289	0.706	no	no	no	no	no	no	HC
Blautia	IP-10	Blautia+Peroxisome-Thermogenesis-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia+Arginine and proline metabolism-Thermogenesis-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia+Peroxisome-Amyotrophic lateral sclerosis-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia-Cushing syndrome+Amyotrophic lateral sclerosis-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia+Arginine and proline metabolism-Amyotrophic lateral sclerosis-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia+Peroxisome-Alzheimer disease-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia-Cushing syndrome+Alzheimer disease-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia-Ras signaling pathway+Neurotrophin signaling pathway-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia+P-hydroxyhippuric acid+urine-FGF basic-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia-Chemical carcinogenesis - receptor activation+L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia-18:1-LPE+blood+L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia+Peroxisome-Cardiac muscle contraction-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia-Ras signaling pathway+Signaling pathways regulating pluripotency of stem cells-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia+Peroxisome-Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia-Chemical carcinogenesis - receptor activation+Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia-Cushing syndrome+Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia+Peroxisome-Huntington disease-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia-Cushing syndrome+Huntington disease-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia-18:1-LPE+blood-TXB2+blood+IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia+Arginine and proline metabolism+18:1/20:4-PC+blood-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	Blautia+Peroxisome-Non-alcoholic fatty liver disease-IP-10	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Blautia	IP-10	"Blautia+Peroxisome-Parathyroid hormone synthesis, secretion and action-IP-10"	Indirect	Genus	serum_cytokines	1.36E-05	0.394	up	dn	dn	no	no	no	HC
Parabacteroides	IP-10	Parabacteroides-Pathways in cancer-IP-10	Indirect	Genus	serum_cytokines	4.19E-05	0.394	no	up	up	no	no	no	HC
Dorea	IP-10	Dorea-VEGF signaling pathway+Signaling pathways regulating pluripotency of stem cells-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-Endocrine resistance+Signaling pathways regulating pluripotency of stem cells-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-Endocrine resistance+Huntington disease-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-Endocrine resistance+L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-Chemical carcinogenesis - receptor activation+L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	"Dorea-Growth hormone synthesis, secretion and action+L-Homocystine+blood-IP-10"	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-Endocrine resistance+Non-alcoholic fatty liver disease-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-GnRH signaling pathway+Non-alcoholic fatty liver disease-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	"Dorea-Endocrine resistance+Parathyroid hormone synthesis, secretion and action-IP-10"	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	"Dorea-GnRH signaling pathway+Parathyroid hormone synthesis, secretion and action-IP-10"	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-VEGF signaling pathway+Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-Thyroid hormone signaling pathway-Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-Fc epsilon RI signaling pathway+Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-Endocrine resistance+Thermogenesis-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-16:0-LPC+blood+TXB2+blood+IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-VEGF signaling pathway+MicroRNAs in cancer-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-VEGF signaling pathway+Neurotrophin signaling pathway-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-Fc epsilon RI signaling pathway+Neurotrophin signaling pathway-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea+Legionellosis-Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-Amphetamine addiction+Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-Chemical carcinogenesis - receptor activation+Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-Endocrine resistance+Amyotrophic lateral sclerosis-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-GnRH signaling pathway+Amyotrophic lateral sclerosis-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-VEGF signaling pathway+Pathways in cancer-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-Fc epsilon RI signaling pathway+Pathways in cancer-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	"Dorea-Growth hormone synthesis, secretion and action+Pathways in cancer-IP-10"	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-VEGF signaling pathway+Progesterone-mediated oocyte maturation-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-VEGF signaling pathway+Prostate cancer-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-Fc epsilon RI signaling pathway+Prostate cancer-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	"Dorea-Growth hormone synthesis, secretion and action+Prostate cancer-IP-10"	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Dorea	IP-10	Dorea-Endocrine resistance+Alzheimer disease-IP-10	Indirect	Genus	serum_cytokines	0.00362	0.394	up	no	dn	no	no	no	HC
Faecalibacterium	IP-10	Faecalibacterium-IP-10	Direct	Genus	serum_cytokines	0.0039	0.394	no	dn	dn	no	no	no	HC
TUDCA+blood	IP-10	TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.0282	0.394	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	IP-10	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IP-10	Indirect	serum_scfa	serum_cytokines	0.0458	0.394	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	IP-10	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_scfa	serum_cytokines	0.0458	0.394	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	IP-10	isocapric acid iso-C6+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_scfa	serum_cytokines	0.0458	0.394	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	IP-10	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Arginine+blood+L-Citrulline+blood+L-Homocystine+blood-IP-10	Indirect	serum_scfa	serum_cytokines	0.0458	0.394	no	no	dn	no	no	no	HC
Bacteroides	IP-10	Bacteroides-Amyotrophic lateral sclerosis-IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	HC
Bacteroides	IP-10	Bacteroides-FGF basic-IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	HC
Bacteroides	IP-10	Bacteroides-L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	HC
Bacteroides	IP-10	Bacteroides+TXB2+blood+IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	HC
Bacteroides	IP-10	Bacteroides-Thermogenesis-IP-10	Indirect	Genus	serum_cytokines	0.000267	0.394	dn	dn	up	no	no	no	HC
Propionic acid+stool	IP-10	Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	HC
Propionic acid+stool	IP-10	Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	HC
Propionic acid+stool	IP-10	Propionic acid+stool+16:0/18:2-PI+blood-18:1/20:4-PC+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0436	0.394	dn	no	up	no	no	no	HC
[Ruminococcus]	IP-10	[Ruminococcus]+nutriCA+stool-L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.0679	0.394	no	no	dn	no	no	no	HC
[Ruminococcus]	IP-10	[Ruminococcus]-18:0/20:4-PI+blood+18:1/20:4-PC+blood-IP-10	Indirect	Genus	serum_cytokines	0.0679	0.394	no	no	dn	no	no	no	HC
GUDCA+blood	IP-10	GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.0766	0.394	no	no	dn	no	no	no	HC
GUDCA+blood	IP-10	GUDCA+blood-PUFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.0766	0.394	no	no	dn	no	no	no	HC
GUDCA+blood	IP-10	GUDCA+blood-UFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.0766	0.394	no	no	dn	no	no	no	HC
GUDCA+blood	IP-10	GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.0766	0.394	no	no	dn	no	no	no	HC
GUDCA+blood	IP-10	GUDCA+blood+TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.0766	0.394	no	no	dn	no	no	no	HC
GUDCA+blood	IP-10	GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.0766	0.394	no	no	dn	no	no	no	HC
Acetic acid+stool	IP-10	Acetic acid+stool-L-Homocystine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.0656	0.394	dn	no	no	no	no	no	HC
Alistipes	IP-10	Alistipes-Progesterone-mediated oocyte maturation-IP-10	Indirect	Genus	serum_cytokines	0.0114	0.394	no	up	no	no	no	no	HC
Butyricimonas	IP-10	Butyricimonas+Neurotrophin signaling pathway-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	HC
Butyricimonas	IP-10	Butyricimonas+Non-alcoholic fatty liver disease-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	HC
Butyricimonas	IP-10	Butyricimonas+Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	HC
Butyricimonas	IP-10	"Butyricimonas+Parathyroid hormone synthesis, secretion and action-IP-10"	Indirect	Genus	serum_cytokines	0.17	0.394	no	no	no	no	no	no	HC
Collinsella	IP-10	Collinsella+IP-10	Direct	Genus	serum_cytokines	0.128	0.394	no	no	no	no	no	no	HC
iso-DCA+stool	IP-10	iso-DCA+stool-nutriCA+stool-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.155	0.394	no	no	no	no	no	no	HC
LCA+stool	IP-10	LCA+stool+16:0/18:1-PC+blood+18:1/20:4-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	HC
LCA+stool	IP-10	LCA+stool+18:0/16:0-PC+blood+18:1/20:4-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	HC
LCA+stool	IP-10	LCA+stool-nutriCA+stool-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	HC
LCA+stool	IP-10	LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	HC
LCA+stool	IP-10	LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	HC
LCA+stool	IP-10	LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	HC
LCA+stool	IP-10	LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	HC
LCA+stool	IP-10	LCA+stool-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.314	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Ribosome+Cardiac muscle contraction-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Ribosome+Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Wnt signaling pathway+Thermogenesis-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Ribosome+Thermogenesis-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Wnt signaling pathway+Alzheimer disease-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Ribosome+Alzheimer disease-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Wnt signaling pathway+Signaling pathways regulating pluripotency of stem cells-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Ribosome+Signaling pathways regulating pluripotency of stem cells-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Wnt signaling pathway+Amyotrophic lateral sclerosis-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Ribosome+Amyotrophic lateral sclerosis-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Acetic acid+stool-L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Wnt signaling pathway+Neurotrophin signaling pathway-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Ribosome+Neurotrophin signaling pathway-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Wnt signaling pathway+Non-alcoholic fatty liver disease-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Ribosome+Non-alcoholic fatty liver disease-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Wnt signaling pathway+Huntington disease-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Ribosome+Huntington disease-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	"Akkermansia-Wnt signaling pathway+Parathyroid hormone synthesis, secretion and action-IP-10"	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	"Akkermansia-Ribosome+Parathyroid hormone synthesis, secretion and action-IP-10"	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Wnt signaling pathway+Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Coronavirus disease - COVID-19+Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Ribosome+Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia+Systemic lupus erythematosus-Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Akkermansia	IP-10	Akkermansia-Wnt signaling pathway+Pathways in cancer-IP-10	Indirect	Genus	serum_cytokines	0.23	0.394	no	no	no	no	no	no	HC
Bifidobacterium	IP-10	Bifidobacterium+TXB2+blood+IP-10	Indirect	Genus	serum_cytokines	0.105	0.394	no	dn	no	no	no	no	HC
Ruminococcus	IP-10	Ruminococcus+Thermogenesis-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	HC
Ruminococcus	IP-10	Ruminococcus-MicroRNAs in cancer-IP-10	Indirect	Genus	serum_cytokines	0.335	0.394	no	no	no	no	no	no	HC
GCDCA+blood	IP-10	GCDCA+blood-iso-DCA+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.31	0.394	no	no	no	no	no	no	HC
GCDCA+blood	IP-10	GCDCA+blood-UFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.31	0.394	no	no	no	no	no	no	HC
GCDCA+blood	IP-10	GCDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.31	0.394	no	no	no	no	no	no	HC
GCDCA+blood	IP-10	GCDCA+blood-PUFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.31	0.394	no	no	no	no	no	no	HC
GCDCA+blood	IP-10	GCDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.31	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	[Prevotella]-Gap junction-18:1/20:4-PC+blood-IP-10	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	[Prevotella]-Aldosterone synthesis and secretion+Alzheimer disease-IP-10	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	[Prevotella]-18:0/22:6-PC+blood+TXB2+blood+IP-10	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	[Prevotella]-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis-IP-10	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	[Prevotella]-GnRH signaling pathway+Amyotrophic lateral sclerosis-IP-10	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	[Prevotella]-Aldosterone synthesis and secretion+Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	[Prevotella]-Morphine addiction+Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	"[Prevotella]-Growth hormone synthesis, secretion and action+L-Homocystine+blood-IP-10"	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	[Prevotella]-Aldosterone synthesis and secretion+L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	[Prevotella]+24:0+blood-L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	[Prevotella]-Aldosterone synthesis and secretion+Huntington disease-IP-10	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	"[Prevotella]-Aldosterone synthesis and secretion+Parathyroid hormone synthesis, secretion and action-IP-10"	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	"[Prevotella]-GnRH signaling pathway+Parathyroid hormone synthesis, secretion and action-IP-10"	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	[Prevotella]-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease-IP-10	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	[Prevotella]-GnRH signaling pathway+Non-alcoholic fatty liver disease-IP-10	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	"[Prevotella]-Growth hormone synthesis, secretion and action+Pathways in cancer-IP-10"	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	[Prevotella]-Aldosterone synthesis and secretion+Pathways in cancer-IP-10	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
[Prevotella]	IP-10	"[Prevotella]-Growth hormone synthesis, secretion and action+Prostate cancer-IP-10"	Indirect	Genus	serum_cytokines	0.367	0.394	no	no	no	no	no	no	HC
ACA+blood	IP-10	ACA+blood-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.338	0.394	no	no	no	no	no	no	HC
ACA+blood	IP-10	ACA+blood-P-hydroxyhippuric acid+urine-FGF basic-IP-10	Indirect	serum_bileacids	serum_cytokines	0.338	0.394	no	no	no	no	no	no	HC
DCA+stool	IP-10	DCA+stool-8-HETE+blood+TXB2+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	HC
DCA+stool	IP-10	DCA+stool-20:1-LPA+blood-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	HC
DCA+stool	IP-10	DCA+stool-8-HETE+blood-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	HC
DCA+stool	IP-10	DCA+stool-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	HC
DCA+stool	IP-10	DCA+stool-DL-methionine sulfoxide+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.195	0.394	no	no	no	no	no	no	HC
2-hydroxyhippuric acid+urine	IP-10	2-hydroxyhippuric acid+urine-L-Tryptophan+urine-IP-10	Indirect	urine_cometabolism	serum_cytokines	0.215	0.394	no	no	no	no	no	no	HC
Butyric acid+stool	IP-10	Butyric acid+stool+16:0/16:0-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	HC
Butyric acid+stool	IP-10	Butyric acid+stool-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	HC
Butyric acid+stool	IP-10	Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic-IP-10	Indirect	stool_scfa	serum_cytokines	0.102	0.394	dn	no	no	no	no	no	HC
4-hydroxybenzoic acid+stool	IP-10	4-hydroxybenzoic acid+stool-L-Homocystine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.394	no	dn	no	no	no	no	HC
GCA+blood	IP-10	GCA+blood-iso-DCA+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.16	0.394	no	no	no	no	no	no	HC
GCA+blood	IP-10	GCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.16	0.394	no	no	no	no	no	no	HC
GCA+blood	IP-10	GCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.16	0.394	no	no	no	no	no	no	HC
ACA+stool	IP-10	ACA+stool+UFA%+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.417	0.394	no	no	no	no	no	no	HC
ACA+stool	IP-10	ACA+stool-Acetic acid+stool-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.417	0.394	no	no	no	no	no	no	HC
CDCA+blood	IP-10	CDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.506	0.394	no	no	no	no	no	no	HC
capric acid C6+blood	IP-10	capric acid C6+blood-Cystine+blood+UFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_scfa	serum_cytokines	0.433	0.394	no	no	no	no	no	no	HC
capric acid C6+blood	IP-10	capric acid C6+blood-Cystine+blood+L-Aspartic acid+blood+TXB2+blood+IP-10	Indirect	serum_scfa	serum_cytokines	0.433	0.394	no	no	no	no	no	no	HC
Prevotella	IP-10	Prevotella-18:1/20:4-PC+blood-IP-10	Indirect	Genus	serum_cytokines	0.287	0.394	no	no	no	no	no	no	HC
TCA+blood	IP-10	TCA+blood+TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.339	0.394	no	no	no	no	no	no	HC
TCA+blood	IP-10	TCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IP-10	Indirect	serum_bileacids	serum_cytokines	0.339	0.394	no	no	no	no	no	no	HC
iso-DCA+blood	IP-10	iso-DCA+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.38	0.394	no	no	no	no	no	no	HC
HCA+stool	IP-10	HCA+stool-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.155	0.394	no	no	no	no	no	no	HC
Roseburia	IP-10	Roseburia-Prostate cancer-IP-10	Indirect	Genus	serum_cytokines	0.495	0.394	no	no	no	no	no	no	HC
Roseburia	IP-10	Roseburia-L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.495	0.394	no	no	no	no	no	no	HC
Roseburia	IP-10	Roseburia-Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.495	0.394	no	no	no	no	no	no	HC
Roseburia	IP-10	Roseburia+TXB2+blood+IP-10	Indirect	Genus	serum_cytokines	0.495	0.394	no	no	no	no	no	no	HC
Roseburia	IP-10	Roseburia-Neurotrophin signaling pathway-IP-10	Indirect	Genus	serum_cytokines	0.495	0.394	no	no	no	no	no	no	HC
12-ketoDCA+stool	IP-10	12-ketoDCA+stool-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.505	0.394	no	no	no	no	no	no	HC
GLCA+blood	IP-10	GLCA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IP-10	Indirect	serum_bileacids	serum_cytokines	0.319	0.394	no	no	no	no	no	no	HC
GLCA+blood	IP-10	GLCA+blood+L-Glutamine+blood+SFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.319	0.394	no	no	no	no	no	no	HC
GLCA+blood	IP-10	GLCA+blood+L-Glutamine+blood+PUFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.319	0.394	no	no	no	no	no	no	HC
GLCA+blood	IP-10	GLCA+blood+L-Glutamine+blood+UFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.319	0.394	no	no	no	no	no	no	HC
GLCA+blood	IP-10	GLCA+blood+LCA+blood-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.319	0.394	no	no	no	no	no	no	HC
GLCA+blood	IP-10	GLCA+blood+iso-LCA+blood-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.319	0.394	no	no	no	no	no	no	HC
GLCA+blood	IP-10	GLCA+blood+L-Glutamine+blood-Homovanillic acid+urine-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.319	0.394	no	no	no	no	no	no	HC
L-Tryptophan+stool	IP-10	L-Tryptophan+stool+16:0/22:6-PE+blood-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.557	0.394	no	no	no	no	no	no	HC
L-Tryptophan+stool	IP-10	L-Tryptophan+stool+18:1/18:1-PE+blood-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.557	0.394	no	no	no	no	no	no	HC
L-Tryptophan+stool	IP-10	L-Tryptophan+stool+18:1/18:1-PE+blood-18:1/20:4-PC+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.557	0.394	no	no	no	no	no	no	HC
CA+blood	IP-10	CA+blood+LCA+blood-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.606	0.394	no	no	no	no	no	no	HC
CA+blood	IP-10	CA+blood+CDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.606	0.394	no	no	no	no	no	no	HC
CA+blood	IP-10	CA+blood+HCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.606	0.394	no	no	no	no	no	no	HC
CA+blood	IP-10	CA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IP-10	Indirect	serum_bileacids	serum_cytokines	0.606	0.394	no	no	no	no	no	no	HC
GUDCA+stool	IP-10	GUDCA+stool+L-Tryptophan+stool+18:1/18:1-PE+blood-18:1/20:4-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0085	0.394	no	dn	no	no	no	no	HC
GUDCA+stool	IP-10	GUDCA+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-18:1/20:4-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0085	0.394	no	dn	no	no	no	no	HC
GUDCA+stool	IP-10	GUDCA+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0085	0.394	no	dn	no	no	no	no	HC
GUDCA+stool	IP-10	GUDCA+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0085	0.394	no	dn	no	no	no	no	HC
GUDCA+stool	IP-10	GUDCA+stool+Phenylacetic acid+stool-Homovanillic acid+urine-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0085	0.394	no	dn	no	no	no	no	HC
GUDCA+stool	IP-10	GUDCA+stool+Phenylacetic acid+stool+18:1-LPC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0085	0.394	no	dn	no	no	no	no	HC
GUDCA+stool	IP-10	GUDCA+stool+L-Tryptophan+stool+16:0/22:6-PE+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0085	0.394	no	dn	no	no	no	no	HC
GUDCA+stool	IP-10	GUDCA+stool+L-Tryptophan+stool+18:1/18:1-PE+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0085	0.394	no	dn	no	no	no	no	HC
GUDCA+stool	IP-10	GUDCA+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0085	0.394	no	dn	no	no	no	no	HC
GUDCA+stool	IP-10	GUDCA+stool+Phenylacetic acid+stool+20:0+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0085	0.394	no	dn	no	no	no	no	HC
GUDCA+stool	IP-10	GUDCA+stool+Phenylacetic acid+stool+18:2/18:2-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0085	0.394	no	dn	no	no	no	no	HC
L-Phenylalanine+stool	IP-10	L-Phenylalanine+stool+18:1/18:1-PE+blood-18:1/20:4-PC+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.398	0.394	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IP-10	L-Phenylalanine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.398	0.394	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IP-10	L-Phenylalanine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.398	0.394	no	no	no	no	no	no	HC
butyric acid C4+blood	IP-10	butyric acid C4+blood+Cystine+blood+UFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_scfa	serum_cytokines	0.407	0.394	no	no	no	no	no	no	HC
butyric acid C4+blood	IP-10	butyric acid C4+blood+Cystine+blood+L-Aspartic acid+blood+TXB2+blood+IP-10	Indirect	serum_scfa	serum_cytokines	0.407	0.394	no	no	no	no	no	no	HC
GCA+stool	IP-10	GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0809	0.394	no	no	no	no	no	no	HC
GCA+stool	IP-10	GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0809	0.394	no	no	no	no	no	no	HC
GCA+stool	IP-10	GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0809	0.394	no	no	no	no	no	no	HC
GCA+stool	IP-10	GCA+stool+GDCA+stool-TXB2+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.0809	0.394	no	no	no	no	no	no	HC
Coprococcus	IP-10	Coprococcus+Primary immunodeficiency-Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.612	0.394	no	no	no	no	no	no	HC
Coprococcus	IP-10	Coprococcus-Lysosome+18:1/20:4-PC+blood-IP-10	Indirect	Genus	serum_cytokines	0.612	0.394	no	no	no	no	no	no	HC
Coprococcus	IP-10	Coprococcus+Lachnospira-L-Tryptophan+urine-IP-10	Indirect	Genus	serum_cytokines	0.612	0.394	no	no	no	no	no	no	HC
Coprococcus	IP-10	Coprococcus-18:1-LPC+blood+L-Tryptophan+urine-IP-10	Indirect	Genus	serum_cytokines	0.612	0.394	no	no	no	no	no	no	HC
Coprococcus	IP-10	Coprococcus+Homovanillic acid+urine-L-Tryptophan+urine-IP-10	Indirect	Genus	serum_cytokines	0.612	0.394	no	no	no	no	no	no	HC
Coprococcus	IP-10	Coprococcus+Ribosome biogenesis in eukaryotes+Progesterone-mediated oocyte maturation-IP-10	Indirect	Genus	serum_cytokines	0.612	0.394	no	no	no	no	no	no	HC
Oscillospira	IP-10	Oscillospira+L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.62	0.394	no	no	no	no	no	no	HC
HCA+blood	IP-10	HCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.544	0.394	no	no	no	no	no	no	HC
iso-LCA+stool	IP-10	iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.72	0.394	no	no	no	no	no	no	HC
iso-LCA+stool	IP-10	iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.72	0.394	no	no	no	no	no	no	HC
iso-LCA+stool	IP-10	iso-LCA+stool-nutriCA+stool-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.72	0.394	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IP-10	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+UFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_scfa	serum_cytokines	0.262	0.394	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IP-10	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+PUFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_scfa	serum_cytokines	0.262	0.394	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IP-10	2-methyl-butyric acid m-C4+blood+20:1+blood+20:1-LPC+blood-TXB2+blood+IP-10	Indirect	serum_scfa	serum_cytokines	0.262	0.394	no	no	no	no	no	no	HC
DCA+blood	IP-10	DCA+blood+GUDCA+blood-PUFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.122	0.394	no	no	no	no	no	no	HC
DCA+blood	IP-10	DCA+blood+GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.122	0.394	no	no	no	no	no	no	HC
DCA+blood	IP-10	DCA+blood+GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.122	0.394	no	no	no	no	no	no	HC
DCA+blood	IP-10	DCA+blood+GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.122	0.394	no	no	no	no	no	no	HC
DCA+blood	IP-10	DCA+blood+GUDCA+blood-UFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.122	0.394	no	no	no	no	no	no	HC
DCA+blood	IP-10	DCA+blood+GUDCA+blood+TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.122	0.394	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	IP-10	3-(3-Hydroxyphenyl)propanoic acid+stool+18:0/22:6-PC+blood+TXB2+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.33	0.394	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	IP-10	3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.33	0.394	no	no	no	no	no	no	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IP-10	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IP-10"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.394	up	up	no	no	no	no	HC
GLCA+stool	IP-10	GLCA+stool-LCA+stool-nutriCA+stool-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.617	0.394	no	no	no	no	no	no	HC
GLCA+stool	IP-10	GLCA+stool-iso-LCA+stool-nutriCA+stool-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.617	0.394	no	no	no	no	no	no	HC
GLCA+stool	IP-10	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.617	0.394	no	no	no	no	no	no	HC
GLCA+stool	IP-10	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.617	0.394	no	no	no	no	no	no	HC
GLCA+stool	IP-10	GLCA+stool-iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.617	0.394	no	no	no	no	no	no	HC
GLCA+stool	IP-10	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.617	0.394	no	no	no	no	no	no	HC
GLCA+stool	IP-10	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.617	0.394	no	no	no	no	no	no	HC
GLCA+stool	IP-10	GLCA+stool-LCA+stool-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.617	0.394	no	no	no	no	no	no	HC
GLCA+stool	IP-10	GLCA+stool-iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.617	0.394	no	no	no	no	no	no	HC
GLCA+stool	IP-10	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+18:1/20:4-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.617	0.394	no	no	no	no	no	no	HC
GLCA+stool	IP-10	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+18:1/20:4-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.617	0.394	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+18:1-LPC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+18:2/18:2-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+L-Tryptophan+stool+18:1/18:1-PE+blood-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+20:0+blood+L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+L-Tryptophan+stool+16:0/22:6-PE+blood-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-Homovanillic acid+urine-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+L-Phenylalanine+stool+18:1/18:1-PE+blood-18:1/20:4-PC+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+L-Tryptophan+stool+18:1/18:1-PE+blood-18:1/20:4-PC+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IP-10	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-18:1/20:4-PC+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.304	0.394	no	no	no	no	no	no	HC
TCA+stool	IP-10	TCA+stool-18:2/16:0-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	HC
TCA+stool	IP-10	TCA+stool-PUFA%+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	HC
TCA+stool	IP-10	TCA+stool-16:0/18:1-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	HC
TCA+stool	IP-10	TCA+stool-18:1/18:1-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	HC
TCA+stool	IP-10	TCA+stool-18:0/16:0-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	HC
TCA+stool	IP-10	TCA+stool-UFA%+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	HC
TCA+stool	IP-10	TCA+stool-SFA%+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	HC
TCA+stool	IP-10	TCA+stool-iso-DCA+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	HC
TCA+stool	IP-10	TCA+stool-20:0+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	HC
TCA+stool	IP-10	TCA+stool-16:0/18:2-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	HC
TCA+stool	IP-10	TCA+stool-18:1/18:0-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	HC
TCA+stool	IP-10	TCA+stool-18:1/16:0-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	HC
TCA+stool	IP-10	TCA+stool-16:0/18:1-PC+blood+18:1/20:4-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	HC
TCA+stool	IP-10	TCA+stool-18:0/16:0-PC+blood+18:1/20:4-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	HC
TCA+stool	IP-10	TCA+stool-20:0+blood+FGF basic-IP-10	Indirect	stool_bileacids	serum_cytokines	0.458	0.394	no	no	no	no	no	no	HC
HDCA+stool	IP-10	HDCA+stool-nutriCA+stool-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.176	0.394	no	no	no	no	no	no	HC
HDCA+stool	IP-10	HDCA+stool+16:0/20:4-PC+blood+18:1/20:4-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.176	0.394	no	no	no	no	no	no	HC
HDCA+stool	IP-10	HDCA+stool+16:0/18:1-PC+blood+18:1/20:4-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.176	0.394	no	no	no	no	no	no	HC
HDCA+stool	IP-10	HDCA+stool+18:0/16:0-PC+blood+18:1/20:4-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.176	0.394	no	no	no	no	no	no	HC
HDCA+stool	IP-10	HDCA+stool+16:0/20:4-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.176	0.394	no	no	no	no	no	no	HC
HDCA+stool	IP-10	HDCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.176	0.394	no	no	no	no	no	no	HC
HDCA+stool	IP-10	HDCA+stool-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.176	0.394	no	no	no	no	no	no	HC
HDCA+stool	IP-10	HDCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.176	0.394	no	no	no	no	no	no	HC
HDCA+stool	IP-10	HDCA+stool+20:3/16:0-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.176	0.394	no	no	no	no	no	no	HC
Lachnospira	IP-10	Lachnospira-L-Tryptophan+urine-IP-10	Indirect	Genus	serum_cytokines	0.279	0.394	no	no	no	no	no	no	HC
isobutyric acid C4+blood	IP-10	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_scfa	serum_cytokines	0.0151	0.394	up	up	no	no	no	no	HC
GCDCA+stool	IP-10	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood+TXB2+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	HC
GCDCA+stool	IP-10	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood-TXB2+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	HC
GCDCA+stool	IP-10	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-18:1/20:4-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	HC
GCDCA+stool	IP-10	GCDCA+stool+18:0/20:5-PC+blood-18:1/16:1-PE+blood-18:1/20:4-PC+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	HC
GCDCA+stool	IP-10	GCDCA+stool-Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	HC
GCDCA+stool	IP-10	GCDCA+stool-9-HODE+blood+GPC+blood-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	HC
GCDCA+stool	IP-10	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood+L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	HC
GCDCA+stool	IP-10	GCDCA+stool+18:0/20:5-PC+blood+18:2/20:4-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	HC
GCDCA+stool	IP-10	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	HC
GCDCA+stool	IP-10	GCDCA+stool+18:0/20:5-PC+blood+UFA%+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	HC
GCDCA+stool	IP-10	GCDCA+stool+18:0/20:5-PC+blood+PUFA%+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	HC
GCDCA+stool	IP-10	GCDCA+stool+18:0/20:5-PC+blood+18:1/16:0-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	HC
GCDCA+stool	IP-10	GCDCA+stool+18:0/20:5-PC+blood+18:1/18:0-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	HC
GCDCA+stool	IP-10	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	HC
GCDCA+stool	IP-10	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.0471	0.394	no	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool+GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool+GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool+GCA+stool+GDCA+stool-TXB2+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IP-10	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-18:1/20:4-PC+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.394	dn	dn	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Gap junction-18:1/20:4-PC+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter+Arginine and proline metabolism+18:1/20:4-PC+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Endocrine resistance+Huntington disease-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Long-term depression+Huntington disease-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Pancreatic secretion+Huntington disease-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Aldosterone synthesis and secretion+Huntington disease-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Cushing syndrome+Huntington disease-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Endocrine resistance+L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Long-term depression+L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Pancreatic secretion+L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Aldosterone synthesis and secretion+L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Endocrine resistance+Non-alcoholic fatty liver disease-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Long-term depression+Non-alcoholic fatty liver disease-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	"Odoribacter-Endocrine resistance+Parathyroid hormone synthesis, secretion and action-IP-10"	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	"Odoribacter-Long-term depression+Parathyroid hormone synthesis, secretion and action-IP-10"	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	"Odoribacter-Aldosterone synthesis and secretion+Parathyroid hormone synthesis, secretion and action-IP-10"	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Endocrine resistance+Signaling pathways regulating pluripotency of stem cells-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Endocrine resistance+Alzheimer disease-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Long-term depression+Alzheimer disease-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Pancreatic secretion+Alzheimer disease-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Aldosterone synthesis and secretion+Alzheimer disease-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Cushing syndrome+Alzheimer disease-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Endocrine resistance+Thermogenesis-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter+Arginine and proline metabolism-Thermogenesis-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Endocrine resistance+Amyotrophic lateral sclerosis-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Long-term depression+Amyotrophic lateral sclerosis-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter+Arginine and proline metabolism-Amyotrophic lateral sclerosis-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Pancreatic secretion+Amyotrophic lateral sclerosis-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Cushing syndrome+Amyotrophic lateral sclerosis-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Morphine addiction+Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Long-term depression+Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Pancreatic secretion+Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Aldosterone synthesis and secretion+Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Cushing syndrome+Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Odoribacter	IP-10	Odoribacter-Aldosterone synthesis and secretion+Pathways in cancer-IP-10	Indirect	Genus	serum_cytokines	0.798	0.394	no	no	no	no	no	no	HC
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	HC
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+Phenylacetic acid+stool-Homovanillic acid+urine-L-Tryptophan+urine-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	HC
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+Phenylacetic acid+stool+18:1-LPC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	HC
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-L-Tryptophan+urine-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	HC
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+L-Tryptophan+urine-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	HC
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+Phenylacetic acid+stool+18:2/18:2-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	HC
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+Phenylacetic acid+stool-16:0/18:2-PI+blood-18:1/20:4-PC+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	HC
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	HC
Isobutyric acid+stool	IP-10	Isobutyric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IP-10	Indirect	stool_scfa	serum_cytokines	0.408	0.394	no	no	no	no	no	no	HC
Kynurenic acid+stool	IP-10	Kynurenic acid+stool-nutriCA+stool-L-Homocystine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.037	0.394	dn	dn	no	no	no	no	HC
L-Tryptophan+urine	IP-10	L-Tryptophan+urine-IP-10	Direct	urine_cometabolism	serum_cytokines	0.226	0.394	no	no	no	no	no	no	HC
Eggerthella	IP-10	Eggerthella-Faecalibacterium-IP-10	Indirect	Genus	serum_cytokines	0.912	0.394	no	no	no	no	no	no	HC
Anaerotruncus	IP-10	Anaerotruncus-Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.904	0.394	no	no	no	no	no	no	HC
Anaerotruncus	IP-10	Anaerotruncus-Gemmiger-Tuberculosis-Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.904	0.394	no	no	no	no	no	no	HC
Anaerotruncus	IP-10	Anaerotruncus-Gemmiger-Staphylococcus aureus infection-Pathways in cancer-IP-10	Indirect	Genus	serum_cytokines	0.904	0.394	no	no	no	no	no	no	HC
Anaerotruncus	IP-10	Anaerotruncus-Gemmiger-GPC+blood-L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.904	0.394	no	no	no	no	no	no	HC
Anaerotruncus	IP-10	Anaerotruncus-Gemmiger-20:1-LPA+blood-L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.904	0.394	no	no	no	no	no	no	HC
Anaerotruncus	IP-10	Anaerotruncus-Gemmiger-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	Genus	serum_cytokines	0.904	0.394	no	no	no	no	no	no	HC
Anaerostipes	IP-10	Anaerostipes-Th17 cell differentiation-TXB2+blood+IP-10	Indirect	Genus	serum_cytokines	0.568	0.394	no	no	no	no	no	no	HC
Anaerostipes	IP-10	Anaerostipes+L-Phenylalanine+urine+L-Tryptophan+urine-IP-10	Indirect	Genus	serum_cytokines	0.568	0.394	no	no	no	no	no	no	HC
Anaerostipes	IP-10	Anaerostipes-20:0+blood+L-Tryptophan+urine-IP-10	Indirect	Genus	serum_cytokines	0.568	0.394	no	no	no	no	no	no	HC
Anaerostipes	IP-10	Anaerostipes-18:1-LPC+blood+L-Tryptophan+urine-IP-10	Indirect	Genus	serum_cytokines	0.568	0.394	no	no	no	no	no	no	HC
Anaerostipes	IP-10	Anaerostipes-20:0+blood+FGF basic-IP-10	Indirect	Genus	serum_cytokines	0.568	0.394	no	no	no	no	no	no	HC
Anaerostipes	IP-10	Anaerostipes-Th1 and Th2 cell differentiation+18:1/20:4-PC+blood-IP-10	Indirect	Genus	serum_cytokines	0.568	0.394	no	no	no	no	no	no	HC
Isovaleric acid+stool	IP-10	Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood-IP-10	Indirect	stool_scfa	serum_cytokines	0.343	0.394	no	no	no	no	no	no	HC
Paraprevotella	IP-10	Paraprevotella-Prostate cancer-IP-10	Indirect	Genus	serum_cytokines	0.118	0.394	no	no	no	no	no	no	HC
Paraprevotella	IP-10	Paraprevotella-Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.118	0.394	no	no	no	no	no	no	HC
Paraprevotella	IP-10	Paraprevotella-L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.118	0.394	no	no	no	no	no	no	HC
Paraprevotella	IP-10	Paraprevotella-MicroRNAs in cancer-IP-10	Indirect	Genus	serum_cytokines	0.118	0.394	no	no	no	no	no	no	HC
Homovanillic acid+urine	IP-10	Homovanillic acid+urine-L-Tryptophan+urine-IP-10	Indirect	urine_cometabolism	serum_cytokines	0.45	0.394	no	no	no	no	no	no	HC
TDCA+blood	IP-10	TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.155	0.394	no	up	no	no	no	no	HC
iso-LCA+blood	IP-10	iso-LCA+blood-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.507	0.394	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IP-10	¦Ø-MCA+stool-Acetic acid+stool-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.919	0.394	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IP-10	Phenylacetic acid+stool+18:2/18:2-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.785	0.394	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IP-10	Phenylacetic acid+stool-Homovanillic acid+urine-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.785	0.394	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IP-10	Phenylacetic acid+stool+18:1-LPC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.785	0.394	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IP-10	Phenylacetic acid+stool-16:0/18:2-PI+blood-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.785	0.394	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IP-10	Phenylacetic acid+stool+20:0+blood+L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.785	0.394	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IP-10	Phenylacetic acid+stool+20:0+blood+FGF basic-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.785	0.394	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IP-10	Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.785	0.394	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IP-10	Phenylacetic acid+stool-16:0/18:2-PI+blood-18:1/20:4-PC+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.785	0.394	no	no	no	no	no	no	HC
Gemmiger	IP-10	Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.595	0.394	no	no	no	no	no	no	HC
Gemmiger	IP-10	Gemmiger-Tuberculosis-Diabetic cardiomyopathy-IP-10	Indirect	Genus	serum_cytokines	0.595	0.394	no	no	no	no	no	no	HC
Gemmiger	IP-10	Gemmiger-Staphylococcus aureus infection-Pathways in cancer-IP-10	Indirect	Genus	serum_cytokines	0.595	0.394	no	no	no	no	no	no	HC
Gemmiger	IP-10	Gemmiger-GPC+blood-L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.595	0.394	no	no	no	no	no	no	HC
Gemmiger	IP-10	Gemmiger-20:1-LPA+blood-L-Homocystine+blood-IP-10	Indirect	Genus	serum_cytokines	0.595	0.394	no	no	no	no	no	no	HC
Gemmiger	IP-10	Gemmiger-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	Genus	serum_cytokines	0.595	0.394	no	no	no	no	no	no	HC
GDCA+stool	IP-10	GDCA+stool-TXB2+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.656	0.394	no	no	no	no	no	no	HC
L-Tyrosine+stool	IP-10	L-Tyrosine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	HC
L-Tyrosine+stool	IP-10	L-Tyrosine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	HC
L-Tyrosine+stool	IP-10	L-Tyrosine+stool+PUFA%+blood+L-Tryptophan+urine-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	HC
L-Tyrosine+stool	IP-10	L-Tyrosine+stool+20:1-LPA+blood-L-Homocystine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	HC
L-Tyrosine+stool	IP-10	L-Tyrosine+stool+8-HETE+blood-L-Homocystine+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	HC
L-Tyrosine+stool	IP-10	L-Tyrosine+stool+8-HETE+blood+TXB2+blood+IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	HC
L-Tyrosine+stool	IP-10	L-Tyrosine+stool+18:1/18:1-PE+blood-18:1/20:4-PC+blood-IP-10	Indirect	stool_cometabolism	serum_cytokines	0.44	0.394	no	no	no	no	no	no	HC
CDCA+stool	IP-10	CDCA+stool+TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.663	0.394	no	no	no	no	no	no	HC
CDCA+stool	IP-10	CDCA+stool+nutriCA+stool-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.663	0.394	no	no	no	no	no	no	HC
CDCA+stool	IP-10	CDCA+stool+HCA+stool-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.663	0.394	no	no	no	no	no	no	HC
CA+stool	IP-10	CA+stool+nutriCA+stool-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.827	0.394	no	no	no	no	no	no	HC
CA+stool	IP-10	CA+stool+HCA+stool-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.827	0.394	no	no	no	no	no	no	HC
CA+stool	IP-10	CA+stool+GDCA+stool-TXB2+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.827	0.394	no	no	no	no	no	no	HC
CA+stool	IP-10	CA+stool+TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.827	0.394	no	no	no	no	no	no	HC
CA+stool	IP-10	CA+stool-18:1/16:0-PC+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.827	0.394	no	no	no	no	no	no	HC
HDCA+blood	IP-10	HDCA+blood+L-Aspartic acid+blood+TXB2+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.483	0.394	no	no	no	no	no	no	HC
HDCA+blood	IP-10	HDCA+blood+UFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.483	0.394	no	no	no	no	no	no	HC
HDCA+blood	IP-10	HDCA+blood+SFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.483	0.394	no	no	no	no	no	no	HC
HDCA+blood	IP-10	HDCA+blood+PUFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.483	0.394	no	no	no	no	no	no	HC
UDCA+stool	IP-10	UDCA+stool+18:3n3+blood+AA+blood+TXB2+blood+IP-10	Indirect	stool_bileacids	serum_cytokines	0.266	0.394	no	no	no	no	no	no	HC
UDCA+stool	IP-10	UDCA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IP-10	Indirect	stool_bileacids	serum_cytokines	0.266	0.394	no	no	no	no	no	no	HC
UDCA+stool	IP-10	UDCA+stool+18:3n3+blood+AA+blood-FGF basic-IP-10	Indirect	stool_bileacids	serum_cytokines	0.266	0.394	no	no	no	no	no	no	HC
UDCA+stool	IP-10	UDCA+stool+16:0/18:3-PC+blood+d18:1-20:0-SM+blood-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.266	0.394	no	no	no	no	no	no	HC
UDCA+stool	IP-10	UDCA+stool+18:3n3+blood+20:1-LPA+blood-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.266	0.394	no	no	no	no	no	no	HC
UDCA+stool	IP-10	UDCA+stool+18:3n3+blood+UFA%+blood+L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.266	0.394	no	no	no	no	no	no	HC
UDCA+stool	IP-10	UDCA+stool-iso-LCA+blood-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.266	0.394	no	no	no	no	no	no	HC
UDCA+stool	IP-10	UDCA+stool-TMAO+blood-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.266	0.394	no	no	no	no	no	no	HC
UDCA+stool	IP-10	UDCA+stool+16:0/18:3-PC+blood-2-hydroxyhippuric acid+urine-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.266	0.394	no	no	no	no	no	no	HC
UDCA+stool	IP-10	UDCA+stool+18:3n3+blood-2-hydroxyhippuric acid+urine-L-Tryptophan+urine-IP-10	Indirect	stool_bileacids	serum_cytokines	0.266	0.394	no	no	no	no	no	no	HC
LCA+blood	IP-10	LCA+blood-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.884	0.394	no	no	no	no	no	no	HC
LCA+blood	IP-10	LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IP-10	Indirect	serum_bileacids	serum_cytokines	0.884	0.394	no	no	no	no	no	no	HC
nutriCA+stool	IP-10	nutriCA+stool-L-Homocystine+blood-IP-10	Indirect	stool_bileacids	serum_cytokines	0.481	0.394	no	no	no	no	no	no	HC
GDCA+blood	IP-10	GDCA+blood+TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.632	0.394	no	no	no	no	no	no	HC
P-hydroxyhippuric acid+urine	IP-10	P-hydroxyhippuric acid+urine-FGF basic-IP-10	Indirect	urine_cometabolism	serum_cytokines	0.436	0.394	no	no	no	no	no	no	HC
acetic acid C2+blood	IP-10	acetic acid C2+blood-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IP-10	Indirect	serum_scfa	serum_cytokines	0.000193	0.394	up	dn	no	no	no	no	HC
acetic acid C2+blood	IP-10	acetic acid C2+blood-LCA+blood-TUDCA+blood-L-Tryptophan+urine-IP-10	Indirect	serum_scfa	serum_cytokines	0.000193	0.394	up	dn	no	no	no	no	HC
acetic acid C2+blood	IP-10	acetic acid C2+blood-HCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine-IP-10	Indirect	serum_scfa	serum_cytokines	0.000193	0.394	up	dn	no	no	no	no	HC
isovaleric acid iso-C5+blood	IP-10	isovaleric acid iso-C5+blood+Sarcosine+blood-L-Phenylalanine+urine+L-Tryptophan+urine-IP-10	Indirect	serum_scfa	serum_cytokines	0.117	0.394	no	no	no	no	no	no	HC
L-Phenylalanine+urine	IP-10	L-Phenylalanine+urine+L-Tryptophan+urine-IP-10	Indirect	urine_cometabolism	serum_cytokines	0.0908	0.394	no	up	no	no	no	no	HC
Clostridium	IP-10	Clostridium-L-Tryptophan+urine-IP-10	Indirect	Genus	serum_cytokines	0.925	0.394	no	no	no	no	no	no	HC
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-iso-DCA+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	HC
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-18:1-LPC+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	HC
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-UFA%+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	HC
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-18:2/16:0-PC+blood+L-Tryptophan+urine-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	HC
12-ketoDCA+blood	IP-10	12-ketoDCA+blood+16:0/16:1-PI+blood-18:1/20:4-PC+blood-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	HC
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-AA+blood-FGF basic-IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	HC
12-ketoDCA+blood	IP-10	12-ketoDCA+blood-AA+blood+TXB2+blood+IP-10	Indirect	serum_bileacids	serum_cytokines	0.517	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus-16:0-LPC+blood+TXB2+blood+IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus+d18:1-22:0-SM+blood+FGF basic-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus-Thyroid hormone signaling pathway-Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus-Focal adhesion-Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus-Rap1 signaling pathway-Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus-Leukocyte transendothelial migration-Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus-Platelet activation-Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus-Oxytocin signaling pathway-Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus-18:2/16:0-PC+blood+L-Tryptophan+urine-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus-Focal adhesion-Prostate cancer-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus-Platelet activation-Prostate cancer-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus-Oxytocin signaling pathway-Prostate cancer-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus-Focal adhesion-Progesterone-mediated oocyte maturation-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus-Rap1 signaling pathway-Progesterone-mediated oocyte maturation-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus-Platelet activation-Progesterone-mediated oocyte maturation-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus-Focal adhesion-Pathways in cancer-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus-Platelet activation-Pathways in cancer-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
Butyricicoccus	IP-10	Butyricicoccus-Oxytocin signaling pathway-Pathways in cancer-IP-10	Indirect	Genus	serum_cytokines	0.852	0.394	no	no	no	no	no	no	HC
3-Hydroxy-L-kynurenine+urine	IP-10	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine-IP-10	Indirect	urine_cometabolism	serum_cytokines	0.401	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus-16:0-LPC+blood+TXB2+blood+IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus+d18:1-22:0-SM+blood+FGF basic-IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus-Thyroid hormone signaling pathway-Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus-Focal adhesion-Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus-Rap1 signaling pathway-Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus-Leukocyte transendothelial migration-Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus-Platelet activation-Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus-Oxytocin signaling pathway-Insulin resistance-IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus-18:2/16:0-PC+blood+L-Tryptophan+urine-IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus-Focal adhesion-Prostate cancer-IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus-Platelet activation-Prostate cancer-IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus-Oxytocin signaling pathway-Prostate cancer-IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus-Focal adhesion-Progesterone-mediated oocyte maturation-IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus-Rap1 signaling pathway-Progesterone-mediated oocyte maturation-IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus-Platelet activation-Progesterone-mediated oocyte maturation-IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus-Focal adhesion-Pathways in cancer-IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus-Platelet activation-Pathways in cancer-IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Wautersiella	IP-10	Wautersiella+Butyricicoccus-Oxytocin signaling pathway-Pathways in cancer-IP-10	Indirect	Genus	serum_cytokines	0.289	0.394	no	no	no	no	no	no	HC
Blautia	IL-1b	Blautia+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	HC
Blautia	IL-1b	Blautia+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	1.36E-05	0.00358	up	dn	dn	up	up	no	HC
Parabacteroides	IL-1b	Parabacteroides+Biosynthesis of amino acids-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.00358	no	up	up	up	up	no	HC
Parabacteroides	IL-1b	Parabacteroides-RNA degradation+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.00358	no	up	up	up	up	no	HC
Parabacteroides	IL-1b	Parabacteroides-mRNA surveillance pathway+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.00358	no	up	up	up	up	no	HC
Parabacteroides	IL-1b	Parabacteroides+Biosynthesis of amino acids-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.00358	no	up	up	up	up	no	HC
Parabacteroides	IL-1b	Parabacteroides-RNA degradation+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.00358	no	up	up	up	up	no	HC
Parabacteroides	IL-1b	Parabacteroides-mRNA surveillance pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	4.19E-05	0.00358	no	up	up	up	up	no	HC
Dorea	IL-1b	Dorea-VEGF signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Fc epsilon RI signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-18:2-LPC+blood+20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+Huntington disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Chemical carcinogenesis - receptor activation+L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	"Dorea-Growth hormone synthesis, secretion and action+L-Homocystine+blood+FGF basic-IL-13+IL-1b"	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+mRNA surveillance pathway+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+Non-alcoholic fatty liver disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-GnRH signaling pathway+Non-alcoholic fatty liver disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+Parkinson disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-GnRH signaling pathway+Parkinson disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+RNA degradation+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+Thermogenesis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Thyroid hormone signaling pathway+Viral myocarditis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Chemical carcinogenesis - receptor activation-Viral myocarditis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-16:0-LPC+blood+AA+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Amphetamine addiction-Human papillomavirus infection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Amphetamine addiction-Autoimmune thyroid disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Chemical carcinogenesis - receptor activation-Autoimmune thyroid disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-16:0-LPC+blood+TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Amphetamine addiction-Allograft rejection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Chemical carcinogenesis - receptor activation-Allograft rejection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Amphetamine addiction-Graft-versus-host disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Chemical carcinogenesis - receptor activation-Graft-versus-host disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea+Legionellosis-Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Amphetamine addiction+Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Chemical carcinogenesis - receptor activation+Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Amphetamine addiction-Viral carcinogenesis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+Amyotrophic lateral sclerosis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-GnRH signaling pathway+Amyotrophic lateral sclerosis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Chemical carcinogenesis - receptor activation-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+Alzheimer disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-VEGF signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Fc epsilon RI signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-18:2-LPC+blood+20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+Huntington disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Chemical carcinogenesis - receptor activation+L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	"Dorea-Growth hormone synthesis, secretion and action+L-Homocystine+blood+FGF basic+IL-17A-IL-1b"	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+mRNA surveillance pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+Non-alcoholic fatty liver disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-GnRH signaling pathway+Non-alcoholic fatty liver disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+Parkinson disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-GnRH signaling pathway+Parkinson disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+RNA degradation+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+Thermogenesis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Thyroid hormone signaling pathway+Viral myocarditis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Chemical carcinogenesis - receptor activation-Viral myocarditis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-16:0-LPC+blood+AA+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Amphetamine addiction-Human papillomavirus infection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Amphetamine addiction-Autoimmune thyroid disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Chemical carcinogenesis - receptor activation-Autoimmune thyroid disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-16:0-LPC+blood+TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Amphetamine addiction-Allograft rejection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Chemical carcinogenesis - receptor activation-Allograft rejection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Amphetamine addiction-Graft-versus-host disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Chemical carcinogenesis - receptor activation-Graft-versus-host disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea+Legionellosis-Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Amphetamine addiction+Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Chemical carcinogenesis - receptor activation+Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Amphetamine addiction-Viral carcinogenesis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+Amyotrophic lateral sclerosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-GnRH signaling pathway+Amyotrophic lateral sclerosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Chemical carcinogenesis - receptor activation-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Dorea	IL-1b	Dorea-Endocrine resistance+Alzheimer disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.00362	0.00358	up	no	dn	up	up	no	HC
Faecalibacterium	IL-1b	Faecalibacterium+Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0039	0.00358	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-1b	Faecalibacterium-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0039	0.00358	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-1b	Faecalibacterium-Staphylococcus aureus infection+Viral myocarditis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0039	0.00358	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-1b	Faecalibacterium-Staphylococcus aureus infection+Allograft rejection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0039	0.00358	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-1b	Faecalibacterium-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0039	0.00358	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-1b	Faecalibacterium+4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0039	0.00358	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-1b	Faecalibacterium-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0039	0.00358	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-1b	Faecalibacterium+Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0039	0.00358	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-1b	Faecalibacterium-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0039	0.00358	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-1b	Faecalibacterium-Staphylococcus aureus infection+Viral myocarditis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0039	0.00358	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-1b	Faecalibacterium-Staphylococcus aureus infection+Allograft rejection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0039	0.00358	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-1b	Faecalibacterium-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0039	0.00358	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-1b	Faecalibacterium+4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0039	0.00358	no	dn	dn	up	up	no	HC
Faecalibacterium	IL-1b	Faecalibacterium-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0039	0.00358	no	dn	dn	up	up	no	HC
TUDCA+blood	IL-1b	TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0282	0.00358	no	no	dn	up	up	no	HC
TUDCA+blood	IL-1b	TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0282	0.00358	no	no	dn	up	up	no	HC
TUDCA+blood	IL-1b	TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0282	0.00358	no	no	dn	up	up	no	HC
TUDCA+blood	IL-1b	TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0282	0.00358	no	no	dn	up	up	no	HC
isocapric acid iso-C6+blood	IL-1b	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.0458	0.00358	no	no	dn	up	up	no	HC
isocapric acid iso-C6+blood	IL-1b	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.0458	0.00358	no	no	dn	up	up	no	HC
Bacteroides	IL-1b	Bacteroides-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.000267	0.00358	dn	dn	up	up	up	no	HC
Bacteroides	IL-1b	Bacteroides-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.000267	0.00358	dn	dn	up	up	up	no	HC
Propionic acid+stool	IL-1b	Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.00358	dn	no	up	up	up	no	HC
Propionic acid+stool	IL-1b	Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.00358	dn	no	up	up	up	no	HC
Propionic acid+stool	IL-1b	Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.00358	dn	no	up	up	up	no	HC
Propionic acid+stool	IL-1b	Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.00358	dn	no	up	up	up	no	HC
Propionic acid+stool	IL-1b	Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.00358	dn	no	up	up	up	no	HC
Propionic acid+stool	IL-1b	Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.00358	dn	no	up	up	up	no	HC
Propionic acid+stool	IL-1b	Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.00358	dn	no	up	up	up	no	HC
Propionic acid+stool	IL-1b	Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.00358	dn	no	up	up	up	no	HC
Propionic acid+stool	IL-1b	Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.00358	dn	no	up	up	up	no	HC
Propionic acid+stool	IL-1b	Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_scfa	serum_cytokines	0.0436	0.00358	dn	no	up	up	up	no	HC
[Ruminococcus]	IL-1b	[Ruminococcus]+nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	HC
[Ruminococcus]	IL-1b	[Ruminococcus]+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	HC
[Ruminococcus]	IL-1b	[Ruminococcus]-Hypotaurine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	HC
[Ruminococcus]	IL-1b	[Ruminococcus]+nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	HC
[Ruminococcus]	IL-1b	[Ruminococcus]+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	HC
[Ruminococcus]	IL-1b	[Ruminococcus]-Hypotaurine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0679	0.00358	no	no	dn	up	up	no	HC
GUDCA+blood	IL-1b	GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00358	no	no	dn	up	up	no	HC
GUDCA+blood	IL-1b	GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00358	no	no	dn	up	up	no	HC
GUDCA+blood	IL-1b	GUDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00358	no	no	dn	up	up	no	HC
GUDCA+blood	IL-1b	GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00358	no	no	dn	up	up	no	HC
GUDCA+blood	IL-1b	GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00358	no	no	dn	up	up	no	HC
GUDCA+blood	IL-1b	GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00358	no	no	dn	up	up	no	HC
GUDCA+blood	IL-1b	GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00358	no	no	dn	up	up	no	HC
GUDCA+blood	IL-1b	GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00358	no	no	dn	up	up	no	HC
GUDCA+blood	IL-1b	GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00358	no	no	dn	up	up	no	HC
GUDCA+blood	IL-1b	GUDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00358	no	no	dn	up	up	no	HC
GUDCA+blood	IL-1b	GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00358	no	no	dn	up	up	no	HC
GUDCA+blood	IL-1b	GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00358	no	no	dn	up	up	no	HC
GUDCA+blood	IL-1b	GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00358	no	no	dn	up	up	no	HC
GUDCA+blood	IL-1b	GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.0766	0.00358	no	no	dn	up	up	no	HC
Acetic acid+stool	IL-1b	Acetic acid+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.0656	0.00358	dn	no	no	up	up	no	HC
Acetic acid+stool	IL-1b	Acetic acid+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_scfa	serum_cytokines	0.0656	0.00358	dn	no	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+SFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+20:3/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+16:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-GDCA+stool-TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-MAPK signaling pathway-Cell adhesion molecules-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Lipid and atherosclerosis+AA+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Progesterone-mediated oocyte maturation-Allograft rejection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-MAPK signaling pathway-Allograft rejection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Cardiac muscle contraction+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Alzheimer disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Progesterone-mediated oocyte maturation-Autoimmune thyroid disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-MAPK signaling pathway-Autoimmune thyroid disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Prion disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Huntington disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Progesterone-mediated oocyte maturation-Viral myocarditis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Autophagy - animal-Viral myocarditis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-MAPK signaling pathway-Viral myocarditis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Cholinergic synapse-Viral myocarditis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Non-alcoholic fatty liver disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Thermogenesis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-NOD-like receptor signaling pathway-Thermogenesis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Autophagy - animal+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-GABAergic synapse+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-FoxO signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Autophagy - animal+L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-GABAergic synapse-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-FoxO signaling pathway-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-NOD-like receptor signaling pathway-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Olfactory transduction-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Primary immunodeficiency-Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Primary immunodeficiency-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-16:0/18:2-PI+blood-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Central carbon metabolism in cancer-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Olfactory transduction-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Progesterone-mediated oocyte maturation-Type I diabetes mellitus-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-MAPK signaling pathway-Type I diabetes mellitus-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-GABAergic synapse-Amyotrophic lateral sclerosis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Amyotrophic lateral sclerosis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-NOD-like receptor signaling pathway-Amyotrophic lateral sclerosis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Progesterone-mediated oocyte maturation-Graft-versus-host disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-MAPK signaling pathway-Graft-versus-host disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-GABAergic synapse-Parkinson disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Parkinson disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-NOD-like receptor signaling pathway-Parkinson disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+SFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+20:3/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+16:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-GDCA+stool-TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-MAPK signaling pathway-Cell adhesion molecules-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Lipid and atherosclerosis+AA+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Progesterone-mediated oocyte maturation-Allograft rejection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-MAPK signaling pathway-Allograft rejection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Cardiac muscle contraction+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Alzheimer disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Progesterone-mediated oocyte maturation-Autoimmune thyroid disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-MAPK signaling pathway-Autoimmune thyroid disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Prion disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Huntington disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Progesterone-mediated oocyte maturation-Viral myocarditis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Autophagy - animal-Viral myocarditis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-MAPK signaling pathway-Viral myocarditis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Cholinergic synapse-Viral myocarditis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Non-alcoholic fatty liver disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Thermogenesis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-NOD-like receptor signaling pathway-Thermogenesis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Autophagy - animal+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-GABAergic synapse+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-FoxO signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Autophagy - animal+L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-GABAergic synapse-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-FoxO signaling pathway-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-NOD-like receptor signaling pathway-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Olfactory transduction-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Primary immunodeficiency-Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Primary immunodeficiency-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-16:0/18:2-PI+blood-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Central carbon metabolism in cancer-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Olfactory transduction-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Progesterone-mediated oocyte maturation-Type I diabetes mellitus-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-MAPK signaling pathway-Type I diabetes mellitus-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-GABAergic synapse-Amyotrophic lateral sclerosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Amyotrophic lateral sclerosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-NOD-like receptor signaling pathway-Amyotrophic lateral sclerosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Progesterone-mediated oocyte maturation-Graft-versus-host disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-MAPK signaling pathway-Graft-versus-host disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-GABAergic synapse-Parkinson disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-Peroxisome-Parkinson disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Alistipes	IL-1b	Alistipes-NOD-like receptor signaling pathway-Parkinson disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.0114	0.00358	no	up	no	up	up	no	HC
Butyricimonas	IL-1b	Butyricimonas+Prion disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.17	0.00358	no	no	no	up	up	no	HC
Butyricimonas	IL-1b	Butyricimonas+Non-alcoholic fatty liver disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.17	0.00358	no	no	no	up	up	no	HC
Butyricimonas	IL-1b	Butyricimonas+Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.17	0.00358	no	no	no	up	up	no	HC
Butyricimonas	IL-1b	Butyricimonas+Prion disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.17	0.00358	no	no	no	up	up	no	HC
Butyricimonas	IL-1b	Butyricimonas+Non-alcoholic fatty liver disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.17	0.00358	no	no	no	up	up	no	HC
Butyricimonas	IL-1b	Butyricimonas+Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.17	0.00358	no	no	no	up	up	no	HC
Collinsella	IL-1b	Collinsella-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	HC
Collinsella	IL-1b	Collinsella-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.128	0.00358	no	no	no	up	up	no	HC
iso-DCA+stool	IL-1b	iso-DCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.00358	no	no	no	up	up	no	HC
iso-DCA+stool	IL-1b	iso-DCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	"LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+FGF basic-IL-13+IL-1b"	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool-TCA+stool-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	"LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+FGF basic+IL-17A-IL-1b"	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool-TCA+stool-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
LCA+stool	IL-1b	LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.314	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia+Systemic lupus erythematosus+Graft-versus-host disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome-Phagosome-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Cardiac muscle contraction+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Retrograde endocannabinoid signaling+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Prion disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Prion disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome-Endocytosis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Thermogenesis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Thermogenesis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Alzheimer disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Alzheimer disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+mRNA surveillance pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Amyotrophic lateral sclerosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Amyotrophic lateral sclerosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia+Pertussis+16:0/22:6-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia+Systemic lupus erythematosus+Allograft rejection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+RNA degradation+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Acetic acid+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway-Cell adhesion molecules-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome-Cell adhesion molecules-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway-Human papillomavirus infection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia+Pertussis+Human papillomavirus infection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome-Human papillomavirus infection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway-Natural killer cell mediated cytotoxicity-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome-Natural killer cell mediated cytotoxicity-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Non-alcoholic fatty liver disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Non-alcoholic fatty liver disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Huntington disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Huntington disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Parkinson disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Parkinson disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Coronavirus disease - COVID-19+Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia+Systemic lupus erythematosus-Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia+Systemic lupus erythematosus+Graft-versus-host disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome-Phagosome-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Cardiac muscle contraction+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Retrograde endocannabinoid signaling+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Prion disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Prion disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome-Endocytosis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Thermogenesis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Thermogenesis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Alzheimer disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Alzheimer disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+mRNA surveillance pathway+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Amyotrophic lateral sclerosis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Amyotrophic lateral sclerosis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia+Pertussis+16:0/22:6-PC+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia+Systemic lupus erythematosus+Allograft rejection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+RNA degradation+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Acetic acid+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway-Cell adhesion molecules-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome-Cell adhesion molecules-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway-Human papillomavirus infection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia+Pertussis+Human papillomavirus infection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome-Human papillomavirus infection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway-Natural killer cell mediated cytotoxicity-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome-Natural killer cell mediated cytotoxicity-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Non-alcoholic fatty liver disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Non-alcoholic fatty liver disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Huntington disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Huntington disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Parkinson disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Parkinson disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Wnt signaling pathway+Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Coronavirus disease - COVID-19+Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia-Ribosome+Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Akkermansia	IL-1b	Akkermansia+Systemic lupus erythematosus-Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.23	0.00358	no	no	no	up	up	no	HC
Bifidobacterium	IL-1b	Bifidobacterium+TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	HC
Bifidobacterium	IL-1b	Bifidobacterium+AA+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	HC
Bifidobacterium	IL-1b	Bifidobacterium+TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	HC
Bifidobacterium	IL-1b	Bifidobacterium+AA+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.105	0.00358	no	dn	no	up	up	no	HC
Ruminococcus	IL-1b	Ruminococcus+Thermogenesis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	HC
Ruminococcus	IL-1b	Ruminococcus-Endocytosis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	HC
Ruminococcus	IL-1b	Ruminococcus-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	HC
Ruminococcus	IL-1b	Ruminococcus-Biosynthesis of amino acids-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	HC
Ruminococcus	IL-1b	Ruminococcus+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	HC
Ruminococcus	IL-1b	Ruminococcus+Thermogenesis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	HC
Ruminococcus	IL-1b	Ruminococcus-Endocytosis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	HC
Ruminococcus	IL-1b	Ruminococcus-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	HC
Ruminococcus	IL-1b	Ruminococcus-Biosynthesis of amino acids-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	HC
Ruminococcus	IL-1b	Ruminococcus+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.335	0.00358	no	no	no	up	up	no	HC
GCDCA+blood	IL-1b	GCDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.00358	no	no	no	up	up	no	HC
GCDCA+blood	IL-1b	GCDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.00358	no	no	no	up	up	no	HC
GCDCA+blood	IL-1b	GCDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.00358	no	no	no	up	up	no	HC
GCDCA+blood	IL-1b	GCDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.00358	no	no	no	up	up	no	HC
GCDCA+blood	IL-1b	GCDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.00358	no	no	no	up	up	no	HC
GCDCA+blood	IL-1b	GCDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.00358	no	no	no	up	up	no	HC
GCDCA+blood	IL-1b	GCDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.00358	no	no	no	up	up	no	HC
GCDCA+blood	IL-1b	GCDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.00358	no	no	no	up	up	no	HC
GCDCA+blood	IL-1b	GCDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.00358	no	no	no	up	up	no	HC
GCDCA+blood	IL-1b	GCDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.31	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-18:0/22:6-PC+blood-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Glutamatergic synapse-d18:1-22:0-SM+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]+24:0+blood+AA+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+Alzheimer disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-18:0/22:6-PC+blood+TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-GnRH signaling pathway+Amyotrophic lateral sclerosis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Morphine addiction+Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	"[Prevotella]-Growth hormone synthesis, secretion and action+L-Homocystine+blood+FGF basic-IL-13+IL-1b"	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]+24:0+blood-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+Huntington disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+Parkinson disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-GnRH signaling pathway+Parkinson disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-GnRH signaling pathway+Non-alcoholic fatty liver disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+Prion disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-18:0/22:6-PC+blood-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Glutamatergic synapse-d18:1-22:0-SM+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]+24:0+blood+AA+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+Alzheimer disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-18:0/22:6-PC+blood+TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-GnRH signaling pathway+Amyotrophic lateral sclerosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Morphine addiction+Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	"[Prevotella]-Growth hormone synthesis, secretion and action+L-Homocystine+blood+FGF basic+IL-17A-IL-1b"	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]+24:0+blood-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+Huntington disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+Parkinson disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-GnRH signaling pathway+Parkinson disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-GnRH signaling pathway+Non-alcoholic fatty liver disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+Prion disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
[Prevotella]	IL-1b	[Prevotella]+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.367	0.00358	no	no	no	up	up	no	HC
ACA+blood	IL-1b	ACA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.338	0.00358	no	no	no	up	up	no	HC
ACA+blood	IL-1b	ACA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.338	0.00358	no	no	no	up	up	no	HC
DCA+stool	IL-1b	DCA+stool-8-HETE+blood+TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	HC
DCA+stool	IL-1b	DCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	HC
DCA+stool	IL-1b	DCA+stool-20:1-LPA+blood-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	HC
DCA+stool	IL-1b	DCA+stool-8-HETE+blood-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	HC
DCA+stool	IL-1b	DCA+stool-8-HETE+blood+AA+blood-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	HC
DCA+stool	IL-1b	DCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	HC
DCA+stool	IL-1b	DCA+stool-DL-methionine sulfoxide+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	HC
DCA+stool	IL-1b	DCA+stool-8-HETE+blood+TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	HC
DCA+stool	IL-1b	DCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	HC
DCA+stool	IL-1b	DCA+stool-20:1-LPA+blood-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	HC
DCA+stool	IL-1b	DCA+stool-8-HETE+blood-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	HC
DCA+stool	IL-1b	DCA+stool-8-HETE+blood+AA+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	HC
DCA+stool	IL-1b	DCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	HC
DCA+stool	IL-1b	DCA+stool-DL-methionine sulfoxide+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.195	0.00358	no	no	no	up	up	no	HC
2-hydroxyhippuric acid+urine	IL-1b	2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	urine_cometabolism	serum_cytokines	0.215	0.00358	no	no	no	up	up	no	HC
2-hydroxyhippuric acid+urine	IL-1b	2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	urine_cometabolism	serum_cytokines	0.215	0.00358	no	no	no	up	up	no	HC
Butyric acid+stool	IL-1b	Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.00358	dn	no	no	up	up	no	HC
Butyric acid+stool	IL-1b	Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic-IL-13+IL-1b	Indirect	stool_scfa	serum_cytokines	0.102	0.00358	dn	no	no	up	up	no	HC
4-hydroxybenzoic acid+stool	IL-1b	4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.00358	no	dn	no	up	up	no	HC
4-hydroxybenzoic acid+stool	IL-1b	4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.00358	no	dn	no	up	up	no	HC
GCA+blood	IL-1b	GCA+blood+TCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.16	0.00358	no	no	no	up	up	no	HC
GCA+blood	IL-1b	GCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.16	0.00358	no	no	no	up	up	no	HC
GCA+blood	IL-1b	GCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.16	0.00358	no	no	no	up	up	no	HC
GCA+blood	IL-1b	GCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.16	0.00358	no	no	no	up	up	no	HC
GCA+blood	IL-1b	GCA+blood+TCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.16	0.00358	no	no	no	up	up	no	HC
GCA+blood	IL-1b	GCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.16	0.00358	no	no	no	up	up	no	HC
GCA+blood	IL-1b	GCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.16	0.00358	no	no	no	up	up	no	HC
GCA+blood	IL-1b	GCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.16	0.00358	no	no	no	up	up	no	HC
ACA+stool	IL-1b	ACA+stool+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.417	0.00358	no	no	no	up	up	no	HC
ACA+stool	IL-1b	ACA+stool-Acetic acid+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.417	0.00358	no	no	no	up	up	no	HC
ACA+stool	IL-1b	ACA+stool+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.417	0.00358	no	no	no	up	up	no	HC
ACA+stool	IL-1b	ACA+stool-Acetic acid+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.417	0.00358	no	no	no	up	up	no	HC
CDCA+blood	IL-1b	CDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.00358	no	no	no	up	up	no	HC
CDCA+blood	IL-1b	CDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.506	0.00358	no	no	no	up	up	no	HC
capric acid C6+blood	IL-1b	capric acid C6+blood-Cystine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.433	0.00358	no	no	no	up	up	no	HC
capric acid C6+blood	IL-1b	capric acid C6+blood-Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.433	0.00358	no	no	no	up	up	no	HC
capric acid C6+blood	IL-1b	capric acid C6+blood-Cystine+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.433	0.00358	no	no	no	up	up	no	HC
capric acid C6+blood	IL-1b	capric acid C6+blood-Cystine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.433	0.00358	no	no	no	up	up	no	HC
capric acid C6+blood	IL-1b	capric acid C6+blood-Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.433	0.00358	no	no	no	up	up	no	HC
capric acid C6+blood	IL-1b	capric acid C6+blood-Cystine+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.433	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-Lysosome+Phagosome-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-18:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-16:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-16:0/20:3-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-18:1/18:1-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-SFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-16:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-18:1/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+18:0/18:1-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-24:1+blood-d18:1-22:0-SM+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+12-ketoDCA+blood-AA+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-16:1/16:0-PC+blood+AA+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-16:1/16:1-PC+blood+AA+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Human papillomavirus infection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Viral carcinogenesis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+Estrogen signaling pathway-Viral carcinogenesis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-Lysosome+Viral carcinogenesis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+18:1-LPE+blood+L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-18:1/18:1-PC+blood+20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+18:1-LPE+blood-TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+Estrogen signaling pathway-Autoimmune thyroid disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+Estrogen signaling pathway-Allograft rejection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+Estrogen signaling pathway-Graft-versus-host disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+Estrogen signaling pathway-Type I diabetes mellitus-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+Estrogen signaling pathway-Viral myocarditis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-16:0/16:0-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-Lysosome+Endocytosis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-Lysosome+Natural killer cell mediated cytotoxicity-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-Lysosome+Phagosome-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-18:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-16:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-16:0/20:3-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-18:1/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-SFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-16:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-18:1/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+18:0/18:1-PE+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-24:1+blood-d18:1-22:0-SM+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+12-ketoDCA+blood-AA+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-16:1/16:0-PC+blood+AA+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-16:1/16:1-PC+blood+AA+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Human papillomavirus infection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Viral carcinogenesis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+Estrogen signaling pathway-Viral carcinogenesis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-Lysosome+Viral carcinogenesis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+18:1-LPE+blood+L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-18:1/18:1-PC+blood+20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+18:1-LPE+blood-TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+Estrogen signaling pathway-Autoimmune thyroid disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+Estrogen signaling pathway-Allograft rejection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+Estrogen signaling pathway-Graft-versus-host disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+Estrogen signaling pathway-Type I diabetes mellitus-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella+Estrogen signaling pathway-Viral myocarditis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-16:0/16:0-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-Lysosome+Endocytosis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
Prevotella	IL-1b	Prevotella-Lysosome+Natural killer cell mediated cytotoxicity-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.287	0.00358	no	no	no	up	up	no	HC
TCA+blood	IL-1b	TCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.339	0.00358	no	no	no	up	up	no	HC
TCA+blood	IL-1b	TCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.339	0.00358	no	no	no	up	up	no	HC
iso-DCA+blood	IL-1b	iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.38	0.00358	no	no	no	up	up	no	HC
iso-DCA+blood	IL-1b	iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.38	0.00358	no	no	no	up	up	no	HC
HCA+stool	IL-1b	HCA+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.00358	no	no	no	up	up	no	HC
HCA+stool	IL-1b	HCA+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.155	0.00358	no	no	no	up	up	no	HC
Roseburia	IL-1b	Roseburia-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.495	0.00358	no	no	no	up	up	no	HC
Roseburia	IL-1b	Roseburia+TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.495	0.00358	no	no	no	up	up	no	HC
Roseburia	IL-1b	Roseburia-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.495	0.00358	no	no	no	up	up	no	HC
Roseburia	IL-1b	Roseburia+TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.495	0.00358	no	no	no	up	up	no	HC
12-ketoDCA+stool	IL-1b	12-ketoDCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.00358	no	no	no	up	up	no	HC
12-ketoDCA+stool	IL-1b	12-ketoDCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.00358	no	no	no	up	up	no	HC
12-ketoDCA+stool	IL-1b	12-ketoDCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.00358	no	no	no	up	up	no	HC
12-ketoDCA+stool	IL-1b	12-ketoDCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.505	0.00358	no	no	no	up	up	no	HC
GLCA+blood	IL-1b	GLCA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.319	0.00358	no	no	no	up	up	no	HC
GLCA+blood	IL-1b	GLCA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.319	0.00358	no	no	no	up	up	no	HC
L-Tryptophan+stool	IL-1b	L-Tryptophan+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00358	no	no	no	up	up	no	HC
L-Tryptophan+stool	IL-1b	L-Tryptophan+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00358	no	no	no	up	up	no	HC
L-Tryptophan+stool	IL-1b	L-Tryptophan+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00358	no	no	no	up	up	no	HC
L-Tryptophan+stool	IL-1b	L-Tryptophan+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00358	no	no	no	up	up	no	HC
L-Tryptophan+stool	IL-1b	L-Tryptophan+stool-12-ketoDCA+blood-AA+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00358	no	no	no	up	up	no	HC
L-Tryptophan+stool	IL-1b	L-Tryptophan+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00358	no	no	no	up	up	no	HC
L-Tryptophan+stool	IL-1b	L-Tryptophan+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00358	no	no	no	up	up	no	HC
L-Tryptophan+stool	IL-1b	L-Tryptophan+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00358	no	no	no	up	up	no	HC
L-Tryptophan+stool	IL-1b	L-Tryptophan+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00358	no	no	no	up	up	no	HC
L-Tryptophan+stool	IL-1b	L-Tryptophan+stool-12-ketoDCA+blood-AA+blood-FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.557	0.00358	no	no	no	up	up	no	HC
CA+blood	IL-1b	CA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.606	0.00358	no	no	no	up	up	no	HC
CA+blood	IL-1b	CA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.606	0.00358	no	no	no	up	up	no	HC
GUDCA+stool	IL-1b	GUDCA+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0085	0.00358	no	dn	no	up	up	no	HC
GUDCA+stool	IL-1b	GUDCA+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0085	0.00358	no	dn	no	up	up	no	HC
GUDCA+stool	IL-1b	GUDCA+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0085	0.00358	no	dn	no	up	up	no	HC
GUDCA+stool	IL-1b	GUDCA+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0085	0.00358	no	dn	no	up	up	no	HC
L-Phenylalanine+stool	IL-1b	L-Phenylalanine+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00358	no	no	no	up	up	no	HC
L-Phenylalanine+stool	IL-1b	L-Phenylalanine+stool-12-ketoDCA+blood-AA+blood-FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00358	no	no	no	up	up	no	HC
L-Phenylalanine+stool	IL-1b	L-Phenylalanine+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00358	no	no	no	up	up	no	HC
L-Phenylalanine+stool	IL-1b	L-Phenylalanine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00358	no	no	no	up	up	no	HC
L-Phenylalanine+stool	IL-1b	L-Phenylalanine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00358	no	no	no	up	up	no	HC
L-Phenylalanine+stool	IL-1b	L-Phenylalanine+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00358	no	no	no	up	up	no	HC
L-Phenylalanine+stool	IL-1b	L-Phenylalanine+stool-12-ketoDCA+blood-AA+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00358	no	no	no	up	up	no	HC
L-Phenylalanine+stool	IL-1b	L-Phenylalanine+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00358	no	no	no	up	up	no	HC
L-Phenylalanine+stool	IL-1b	L-Phenylalanine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00358	no	no	no	up	up	no	HC
L-Phenylalanine+stool	IL-1b	L-Phenylalanine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.398	0.00358	no	no	no	up	up	no	HC
butyric acid C4+blood	IL-1b	butyric acid C4+blood+Cystine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.407	0.00358	no	no	no	up	up	no	HC
butyric acid C4+blood	IL-1b	butyric acid C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.407	0.00358	no	no	no	up	up	no	HC
butyric acid C4+blood	IL-1b	butyric acid C4+blood+Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.407	0.00358	no	no	no	up	up	no	HC
butyric acid C4+blood	IL-1b	butyric acid C4+blood+Cystine+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.407	0.00358	no	no	no	up	up	no	HC
butyric acid C4+blood	IL-1b	butyric acid C4+blood+Cystine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.407	0.00358	no	no	no	up	up	no	HC
butyric acid C4+blood	IL-1b	butyric acid C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.407	0.00358	no	no	no	up	up	no	HC
butyric acid C4+blood	IL-1b	butyric acid C4+blood+Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.407	0.00358	no	no	no	up	up	no	HC
butyric acid C4+blood	IL-1b	butyric acid C4+blood+Cystine+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.407	0.00358	no	no	no	up	up	no	HC
GCA+stool	IL-1b	GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	HC
GCA+stool	IL-1b	GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	HC
GCA+stool	IL-1b	GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	HC
GCA+stool	IL-1b	GCA+stool+18:0/22:6-PE+blood-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	HC
GCA+stool	IL-1b	GCA+stool+GDCA+stool-TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	HC
GCA+stool	IL-1b	GCA+stool-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	HC
GCA+stool	IL-1b	GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	HC
GCA+stool	IL-1b	GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	HC
GCA+stool	IL-1b	GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	HC
GCA+stool	IL-1b	GCA+stool+18:0/22:6-PE+blood-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	HC
GCA+stool	IL-1b	GCA+stool+GDCA+stool-TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	HC
GCA+stool	IL-1b	GCA+stool-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0809	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-18:1/18:2-PG+blood+AA+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Lysosome+Viral carcinogenesis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Viral carcinogenesis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Influenza A+Viral carcinogenesis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+TCA+stool-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Primary immunodeficiency-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Central carbon metabolism in cancer-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Lachnospira-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-18:1-LPC+blood+20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-18:2-LPC+blood+20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Primary immunodeficiency-Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Lachnospira-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-18:1-LPC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Lysosome+Endocytosis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Endocytosis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Allograft rejection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Influenza A+Allograft rejection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Cell adhesion molecules-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Autoimmune thyroid disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Influenza A+Autoimmune thyroid disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Cellular senescence-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Lysosome+Natural killer cell mediated cytotoxicity-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Natural killer cell mediated cytotoxicity-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Graft-versus-host disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Influenza A+Graft-versus-host disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Human papillomavirus infection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Influenza A+Human papillomavirus infection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes+mRNA surveillance pathway+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Lysosome+Phagosome-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Phagosome-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes+RNA degradation+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Type I diabetes mellitus-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Viral myocarditis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Influenza A+Viral myocarditis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-18:1/18:2-PG+blood+AA+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Lysosome+Viral carcinogenesis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Viral carcinogenesis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Influenza A+Viral carcinogenesis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+TCA+stool-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Primary immunodeficiency-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Central carbon metabolism in cancer-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Lachnospira-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-18:1-LPC+blood+20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-18:2-LPC+blood+20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Primary immunodeficiency-Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Lachnospira-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-18:1-LPC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Lysosome+Endocytosis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Endocytosis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Allograft rejection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Influenza A+Allograft rejection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Cell adhesion molecules-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Autoimmune thyroid disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Influenza A+Autoimmune thyroid disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Cellular senescence-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Lysosome+Natural killer cell mediated cytotoxicity-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Natural killer cell mediated cytotoxicity-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Graft-versus-host disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Influenza A+Graft-versus-host disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Human papillomavirus infection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Influenza A+Human papillomavirus infection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes+mRNA surveillance pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Lysosome+Phagosome-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Phagosome-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes+RNA degradation+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Type I diabetes mellitus-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus+Ribosome biogenesis in eukaryotes-Viral myocarditis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Coprococcus	IL-1b	Coprococcus-Influenza A+Viral myocarditis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.612	0.00358	no	no	no	up	up	no	HC
Oscillospira	IL-1b	Oscillospira-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	HC
Oscillospira	IL-1b	Oscillospira+L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	HC
Oscillospira	IL-1b	Oscillospira-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	HC
Oscillospira	IL-1b	Oscillospira+L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.62	0.00358	no	no	no	up	up	no	HC
HCA+blood	IL-1b	HCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.544	0.00358	no	no	no	up	up	no	HC
HCA+blood	IL-1b	HCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.544	0.00358	no	no	no	up	up	no	HC
iso-LCA+stool	IL-1b	iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	HC
iso-LCA+stool	IL-1b	iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	HC
iso-LCA+stool	IL-1b	iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	HC
iso-LCA+stool	IL-1b	iso-LCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	HC
iso-LCA+stool	IL-1b	iso-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	HC
iso-LCA+stool	IL-1b	iso-LCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	HC
iso-LCA+stool	IL-1b	iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	HC
iso-LCA+stool	IL-1b	iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	HC
iso-LCA+stool	IL-1b	iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	HC
iso-LCA+stool	IL-1b	iso-LCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	HC
iso-LCA+stool	IL-1b	iso-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	HC
iso-LCA+stool	IL-1b	iso-LCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.72	0.00358	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-1b	2-methyl-butyric acid m-C4+blood+20:1+blood-22:6n3+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.00358	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-1b	2-methyl-butyric acid m-C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.00358	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-1b	2-methyl-butyric acid m-C4+blood+decanoic acid C10+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.00358	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-1b	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.00358	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-1b	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.00358	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-1b	2-methyl-butyric acid m-C4+blood-22:2-LPA+blood-d18:0-24:1-SM+blood+d18:1-22:0-SM+blood+FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.00358	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-1b	2-methyl-butyric acid m-C4+blood+20:1+blood+20:1-LPC+blood-TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.00358	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-1b	2-methyl-butyric acid m-C4+blood+20:1+blood-22:6n3+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.00358	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-1b	2-methyl-butyric acid m-C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.00358	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-1b	2-methyl-butyric acid m-C4+blood+decanoic acid C10+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.00358	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-1b	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.00358	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-1b	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.00358	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-1b	2-methyl-butyric acid m-C4+blood-22:2-LPA+blood-d18:0-24:1-SM+blood+d18:1-22:0-SM+blood+FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.00358	no	no	no	up	up	no	HC
2-methyl-butyric acid m-C4+blood	IL-1b	2-methyl-butyric acid m-C4+blood+20:1+blood+20:1-LPC+blood-TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.262	0.00358	no	no	no	up	up	no	HC
DCA+blood	IL-1b	DCA+blood+GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	HC
DCA+blood	IL-1b	DCA+blood+GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	HC
DCA+blood	IL-1b	DCA+blood+GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	HC
DCA+blood	IL-1b	DCA+blood+GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	HC
DCA+blood	IL-1b	DCA+blood+GUDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	HC
DCA+blood	IL-1b	DCA+blood+GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	HC
DCA+blood	IL-1b	"DCA+blood-n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b"	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	HC
DCA+blood	IL-1b	DCA+blood+GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	HC
DCA+blood	IL-1b	DCA+blood+GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	HC
DCA+blood	IL-1b	DCA+blood+GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	HC
DCA+blood	IL-1b	DCA+blood+GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	HC
DCA+blood	IL-1b	DCA+blood+GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	HC
DCA+blood	IL-1b	DCA+blood+GUDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	HC
DCA+blood	IL-1b	DCA+blood+GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	HC
DCA+blood	IL-1b	"DCA+blood-n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b"	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	HC
DCA+blood	IL-1b	DCA+blood+GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.122	0.00358	no	no	no	up	up	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-1b	3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.33	0.00358	no	no	no	up	up	no	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-1b	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.00358	up	up	no	up	up	no	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-1b	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.00358	up	up	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	"GLCA+stool-LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+FGF basic+IL-17A-IL-1b"	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-iso-LCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-iso-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool-TCA+stool-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	"GLCA+stool-LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+FGF basic-IL-13+IL-1b"	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-iso-LCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-iso-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool-TCA+stool-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
GLCA+stool	IL-1b	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.617	0.00358	no	no	no	up	up	no	HC
Indole-3-Acetic acid+stool	IL-1b	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00358	no	no	no	up	up	no	HC
Indole-3-Acetic acid+stool	IL-1b	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00358	no	no	no	up	up	no	HC
Indole-3-Acetic acid+stool	IL-1b	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00358	no	no	no	up	up	no	HC
Indole-3-Acetic acid+stool	IL-1b	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.304	0.00358	no	no	no	up	up	no	HC
TCA+stool	IL-1b	TCA+stool-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	HC
TCA+stool	IL-1b	TCA+stool-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.458	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool+16:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool+20:3/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool+16:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
HDCA+stool	IL-1b	HDCA+stool+20:3/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.176	0.00358	no	no	no	up	up	no	HC
Lachnospira	IL-1b	Lachnospira-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.279	0.00358	no	no	no	up	up	no	HC
Lachnospira	IL-1b	Lachnospira-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.279	0.00358	no	no	no	up	up	no	HC
Lachnospira	IL-1b	Lachnospira-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.279	0.00358	no	no	no	up	up	no	HC
Lachnospira	IL-1b	Lachnospira-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.279	0.00358	no	no	no	up	up	no	HC
isobutyric acid C4+blood	IL-1b	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.0151	0.00358	up	up	no	up	up	no	HC
isobutyric acid C4+blood	IL-1b	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.0151	0.00358	up	up	no	up	up	no	HC
isobutyric acid C4+blood	IL-1b	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.0151	0.00358	up	up	no	up	up	no	HC
isobutyric acid C4+blood	IL-1b	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.0151	0.00358	up	up	no	up	up	no	HC
isobutyric acid C4+blood	IL-1b	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.0151	0.00358	up	up	no	up	up	no	HC
isobutyric acid C4+blood	IL-1b	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.0151	0.00358	up	up	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-9-HODE+blood-L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood+TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood-TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-9-HODE+blood+GPC+blood-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood+L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood-20:0-LPE+blood+d18:1-22:0-SM+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood+18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood+18:1/18:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-9-HODE+blood-L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood+TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood-TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-9-HODE+blood+GPC+blood-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood+L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood-20:0-LPE+blood+d18:1-22:0-SM+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood+18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood+18:1/18:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
GCDCA+stool	IL-1b	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.0471	0.00358	no	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool+GCA+stool-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool+GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool+GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool+GCA+stool+GDCA+stool-TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool+GCA+stool-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool+GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool+GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool+GCA+stool+GDCA+stool-TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
5-Hydroxytryptamine+stool	IL-1b	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.00358	dn	dn	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+Huntington disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+Huntington disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+Huntington disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+Huntington disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Cushing syndrome+Huntington disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter+Arginine and proline metabolism+Biosynthesis of amino acids-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+mRNA surveillance pathway+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+Prion disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+Prion disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+Prion disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+Non-alcoholic fatty liver disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+Non-alcoholic fatty liver disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+Parkinson disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+Parkinson disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter+Arginine and proline metabolism-Parkinson disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+Parkinson disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+Parkinson disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Cushing syndrome+Parkinson disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter+Arginine and proline metabolism-Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Cushing syndrome+Pathways of neurodegeneration - multiple diseases+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+RNA degradation+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter+Arginine and proline metabolism-RNA degradation+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+Alzheimer disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+Alzheimer disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+Alzheimer disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+Alzheimer disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Cushing syndrome+Alzheimer disease+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Phospholipase D signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+Thermogenesis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter+Arginine and proline metabolism-Thermogenesis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+Amyotrophic lateral sclerosis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+Amyotrophic lateral sclerosis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter+Arginine and proline metabolism-Amyotrophic lateral sclerosis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+Amyotrophic lateral sclerosis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Cushing syndrome+Amyotrophic lateral sclerosis+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Morphine addiction+Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Cushing syndrome+Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+Huntington disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+Huntington disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+Huntington disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+Huntington disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Cushing syndrome+Huntington disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter+Arginine and proline metabolism+Biosynthesis of amino acids-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+mRNA surveillance pathway+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+Prion disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+Prion disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+Prion disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+Non-alcoholic fatty liver disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+Non-alcoholic fatty liver disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+Parkinson disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+Parkinson disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter+Arginine and proline metabolism-Parkinson disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+Parkinson disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+Parkinson disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Cushing syndrome+Parkinson disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter+Arginine and proline metabolism-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Cushing syndrome+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+RNA degradation+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter+Arginine and proline metabolism-RNA degradation+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+Alzheimer disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+Alzheimer disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+Alzheimer disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+Alzheimer disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Cushing syndrome+Alzheimer disease+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Phospholipase D signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+Thermogenesis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter+Arginine and proline metabolism-Thermogenesis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Endocrine resistance+Amyotrophic lateral sclerosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+Amyotrophic lateral sclerosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter+Arginine and proline metabolism-Amyotrophic lateral sclerosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+Amyotrophic lateral sclerosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Cushing syndrome+Amyotrophic lateral sclerosis+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Morphine addiction+Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Long-term depression+Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Pancreatic secretion+Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Aldosterone synthesis and secretion+Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Odoribacter	IL-1b	Odoribacter-Cushing syndrome+Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.798	0.00358	no	no	no	up	up	no	HC
Isobutyric acid+stool	IL-1b	Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.00358	no	no	no	up	up	no	HC
Isobutyric acid+stool	IL-1b	Isobutyric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.00358	no	no	no	up	up	no	HC
Isobutyric acid+stool	IL-1b	Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.00358	no	no	no	up	up	no	HC
Isobutyric acid+stool	IL-1b	Isobutyric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_scfa	serum_cytokines	0.408	0.00358	no	no	no	up	up	no	HC
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	HC
Kynurenic acid+stool	IL-1b	Kynurenic acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.037	0.00358	dn	dn	no	up	up	no	HC
L-Tryptophan+urine	IL-1b	L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	urine_cometabolism	serum_cytokines	0.226	0.00358	no	no	no	up	up	no	HC
L-Tryptophan+urine	IL-1b	L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	urine_cometabolism	serum_cytokines	0.226	0.00358	no	no	no	up	up	no	HC
Eggerthella	IL-1b	Eggerthella+Bacteroides-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.912	0.00358	no	no	no	up	up	no	HC
Eggerthella	IL-1b	Eggerthella+Bacteroides-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.912	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Tuberculosis+Graft-versus-host disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Tuberculosis-Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Viral myocarditis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Tuberculosis+Viral myocarditis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-GPC+blood-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-20:1-LPA+blood-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Allograft rejection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Tuberculosis+Allograft rejection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Tuberculosis+Autoimmune thyroid disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Tuberculosis+Graft-versus-host disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Tuberculosis-Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Viral myocarditis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Tuberculosis+Viral myocarditis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-GPC+blood-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-20:1-LPA+blood-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Allograft rejection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Tuberculosis+Allograft rejection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-Tuberculosis+Autoimmune thyroid disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerotruncus	IL-1b	Anaerotruncus-Gemmiger-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.904	0.00358	no	no	no	up	up	no	HC
Anaerostipes	IL-1b	Anaerostipes-20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.568	0.00358	no	no	no	up	up	no	HC
Anaerostipes	IL-1b	Anaerostipes-20:0+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.568	0.00358	no	no	no	up	up	no	HC
Isovaleric acid+stool	IL-1b	Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.00358	no	no	no	up	up	no	HC
Isovaleric acid+stool	IL-1b	Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.00358	no	no	no	up	up	no	HC
Isovaleric acid+stool	IL-1b	Isovaleric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.00358	no	no	no	up	up	no	HC
Isovaleric acid+stool	IL-1b	Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.00358	no	no	no	up	up	no	HC
Isovaleric acid+stool	IL-1b	Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.00358	no	no	no	up	up	no	HC
Isovaleric acid+stool	IL-1b	Isovaleric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_scfa	serum_cytokines	0.343	0.00358	no	no	no	up	up	no	HC
Paraprevotella	IL-1b	Paraprevotella-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	HC
Paraprevotella	IL-1b	Paraprevotella+AA+blood-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	HC
Paraprevotella	IL-1b	Paraprevotella-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	HC
Paraprevotella	IL-1b	Paraprevotella+AA+blood-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.118	0.00358	no	no	no	up	up	no	HC
Homovanillic acid+urine	IL-1b	Homovanillic acid+urine-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	urine_cometabolism	serum_cytokines	0.45	0.00358	no	no	no	up	up	no	HC
Homovanillic acid+urine	IL-1b	Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	urine_cometabolism	serum_cytokines	0.45	0.00358	no	no	no	up	up	no	HC
Homovanillic acid+urine	IL-1b	Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	urine_cometabolism	serum_cytokines	0.45	0.00358	no	no	no	up	up	no	HC
Homovanillic acid+urine	IL-1b	Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	urine_cometabolism	serum_cytokines	0.45	0.00358	no	no	no	up	up	no	HC
TDCA+blood	IL-1b	TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.155	0.00358	no	up	no	up	up	no	HC
TDCA+blood	IL-1b	TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.155	0.00358	no	up	no	up	up	no	HC
iso-LCA+blood	IL-1b	iso-LCA+blood-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.507	0.00358	no	no	no	up	up	no	HC
iso-LCA+blood	IL-1b	iso-LCA+blood-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.507	0.00358	no	no	no	up	up	no	HC
iso-LCA+blood	IL-1b	iso-LCA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.507	0.00358	no	no	no	up	up	no	HC
iso-LCA+blood	IL-1b	iso-LCA+blood-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.507	0.00358	no	no	no	up	up	no	HC
iso-LCA+blood	IL-1b	iso-LCA+blood-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.507	0.00358	no	no	no	up	up	no	HC
iso-LCA+blood	IL-1b	iso-LCA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.507	0.00358	no	no	no	up	up	no	HC
¦Ø-MCA+stool	IL-1b	¦Ø-MCA+stool-Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.919	0.00358	no	no	no	up	up	no	HC
¦Ø-MCA+stool	IL-1b	¦Ø-MCA+stool-Acetic acid+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.919	0.00358	no	no	no	up	up	no	HC
¦Ø-MCA+stool	IL-1b	¦Ø-MCA+stool-Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.919	0.00358	no	no	no	up	up	no	HC
¦Ø-MCA+stool	IL-1b	¦Ø-MCA+stool-Acetic acid+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.919	0.00358	no	no	no	up	up	no	HC
Phenylacetic acid+stool	IL-1b	Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.00358	no	no	no	up	up	no	HC
Phenylacetic acid+stool	IL-1b	Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.00358	no	no	no	up	up	no	HC
Phenylacetic acid+stool	IL-1b	Phenylacetic acid+stool+20:0+blood+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.00358	no	no	no	up	up	no	HC
Phenylacetic acid+stool	IL-1b	Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.785	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Tuberculosis+Graft-versus-host disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Tuberculosis-Diabetic cardiomyopathy+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Staphylococcus aureus infection+Viral myocarditis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Tuberculosis+Viral myocarditis-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-GPC+blood-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-20:1-LPA+blood-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Staphylococcus aureus infection+Allograft rejection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Tuberculosis+Allograft rejection-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Tuberculosis+Autoimmune thyroid disease-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Tuberculosis+Graft-versus-host disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Tuberculosis-Diabetic cardiomyopathy+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Staphylococcus aureus infection+Viral myocarditis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Tuberculosis+Viral myocarditis-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-GPC+blood-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-20:1-LPA+blood-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Staphylococcus aureus infection+Allograft rejection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Tuberculosis+Allograft rejection-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-Tuberculosis+Autoimmune thyroid disease-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
Gemmiger	IL-1b	Gemmiger-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.595	0.00358	no	no	no	up	up	no	HC
GDCA+stool	IL-1b	GDCA+stool-TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	HC
GDCA+stool	IL-1b	GDCA+stool-TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.656	0.00358	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool+PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool+20:1-LPA+blood-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool+8-HETE+blood-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool-12-ketoDCA+blood-AA+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool+8-HETE+blood+AA+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool+8-HETE+blood+TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool+PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool+20:1-LPA+blood-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool+8-HETE+blood-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool-12-ketoDCA+blood-AA+blood-FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool+8-HETE+blood+AA+blood-FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	HC
L-Tyrosine+stool	IL-1b	L-Tyrosine+stool+8-HETE+blood+TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	stool_cometabolism	serum_cytokines	0.44	0.00358	no	no	no	up	up	no	HC
CDCA+stool	IL-1b	CDCA+stool+18:3n3+blood+AA+blood-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.00358	no	no	no	up	up	no	HC
CDCA+stool	IL-1b	CDCA+stool+TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.00358	no	no	no	up	up	no	HC
CDCA+stool	IL-1b	CDCA+stool+nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.00358	no	no	no	up	up	no	HC
CDCA+stool	IL-1b	CDCA+stool+HCA+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.00358	no	no	no	up	up	no	HC
CDCA+stool	IL-1b	CDCA+stool+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.00358	no	no	no	up	up	no	HC
CDCA+stool	IL-1b	CDCA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.00358	no	no	no	up	up	no	HC
CDCA+stool	IL-1b	CDCA+stool-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.00358	no	no	no	up	up	no	HC
CDCA+stool	IL-1b	CDCA+stool+18:3n3+blood+AA+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.00358	no	no	no	up	up	no	HC
CDCA+stool	IL-1b	CDCA+stool+TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.00358	no	no	no	up	up	no	HC
CDCA+stool	IL-1b	CDCA+stool+nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.00358	no	no	no	up	up	no	HC
CDCA+stool	IL-1b	CDCA+stool+HCA+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.00358	no	no	no	up	up	no	HC
CDCA+stool	IL-1b	CDCA+stool+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.00358	no	no	no	up	up	no	HC
CDCA+stool	IL-1b	CDCA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.00358	no	no	no	up	up	no	HC
CDCA+stool	IL-1b	CDCA+stool-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.663	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool+nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool+HCA+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool-ACA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool+GDCA+stool-TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool+TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool-18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool+nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool+HCA+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool-ACA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool+GDCA+stool-TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool+TUDCA+blood-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
CA+stool	IL-1b	CA+stool-18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.827	0.00358	no	no	no	up	up	no	HC
HDCA+blood	IL-1b	HDCA+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.483	0.00358	no	no	no	up	up	no	HC
HDCA+blood	IL-1b	HDCA+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.483	0.00358	no	no	no	up	up	no	HC
HDCA+blood	IL-1b	HDCA+blood+SFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.483	0.00358	no	no	no	up	up	no	HC
HDCA+blood	IL-1b	HDCA+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.483	0.00358	no	no	no	up	up	no	HC
HDCA+blood	IL-1b	HDCA+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.483	0.00358	no	no	no	up	up	no	HC
HDCA+blood	IL-1b	HDCA+blood+UFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.483	0.00358	no	no	no	up	up	no	HC
HDCA+blood	IL-1b	HDCA+blood+SFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.483	0.00358	no	no	no	up	up	no	HC
HDCA+blood	IL-1b	HDCA+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.483	0.00358	no	no	no	up	up	no	HC
UDCA+stool	IL-1b	UDCA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.00358	no	no	no	up	up	no	HC
UDCA+stool	IL-1b	UDCA+stool+18:3n3+blood+AA+blood-FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.00358	no	no	no	up	up	no	HC
UDCA+stool	IL-1b	UDCA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.00358	no	no	no	up	up	no	HC
UDCA+stool	IL-1b	UDCA+stool+18:3n3+blood+AA+blood-FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.266	0.00358	no	no	no	up	up	no	HC
LCA+blood	IL-1b	LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.884	0.00358	no	no	no	up	up	no	HC
LCA+blood	IL-1b	LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.884	0.00358	no	no	no	up	up	no	HC
nutriCA+stool	IL-1b	nutriCA+stool-L-Homocystine+blood+FGF basic-IL-13+IL-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.00358	no	no	no	up	up	no	HC
nutriCA+stool	IL-1b	nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A-IL-1b	Indirect	stool_bileacids	serum_cytokines	0.481	0.00358	no	no	no	up	up	no	HC
GDCA+blood	IL-1b	GDCA+blood+TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.632	0.00358	no	no	no	up	up	no	HC
GDCA+blood	IL-1b	GDCA+blood+TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.632	0.00358	no	no	no	up	up	no	HC
P-hydroxyhippuric acid+urine	IL-1b	P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	urine_cometabolism	serum_cytokines	0.436	0.00358	no	no	no	up	up	no	HC
P-hydroxyhippuric acid+urine	IL-1b	P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	urine_cometabolism	serum_cytokines	0.436	0.00358	no	no	no	up	up	no	HC
acetic acid C2+blood	IL-1b	acetic acid C2+blood-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.00358	up	dn	no	up	up	no	HC
acetic acid C2+blood	IL-1b	acetic acid C2+blood-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.000193	0.00358	up	dn	no	up	up	no	HC
isovaleric acid iso-C5+blood	IL-1b	isovaleric acid iso-C5+blood+Sarcosine+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	serum_scfa	serum_cytokines	0.117	0.00358	no	no	no	up	up	no	HC
isovaleric acid iso-C5+blood	IL-1b	isovaleric acid iso-C5+blood+Sarcosine+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	serum_scfa	serum_cytokines	0.117	0.00358	no	no	no	up	up	no	HC
L-Phenylalanine+urine	IL-1b	L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	urine_cometabolism	serum_cytokines	0.0908	0.00358	no	up	no	up	up	no	HC
L-Phenylalanine+urine	IL-1b	L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	urine_cometabolism	serum_cytokines	0.0908	0.00358	no	up	no	up	up	no	HC
Clostridium	IL-1b	Clostridium+P-hydroxyhippuric acid+urine-FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	HC
Clostridium	IL-1b	Clostridium-L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	HC
Clostridium	IL-1b	Clostridium+P-hydroxyhippuric acid+urine-FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	HC
Clostridium	IL-1b	Clostridium-L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.925	0.00358	no	no	no	up	up	no	HC
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-AA+blood-FGF basic+IL-17A-IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	HC
12-ketoDCA+blood	IL-1b	12-ketoDCA+blood-AA+blood-FGF basic-IL-13+IL-1b	Indirect	serum_bileacids	serum_cytokines	0.517	0.00358	no	no	no	up	up	no	HC
Butyricicoccus	IL-1b	Butyricicoccus+d18:1-22:0-SM+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	HC
Butyricicoccus	IL-1b	Butyricicoccus+d18:1-22:0-SM+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.852	0.00358	no	no	no	up	up	no	HC
3-Hydroxy-L-kynurenine+urine	IL-1b	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine+FGF basic+IL-17A-IL-1b	Indirect	urine_cometabolism	serum_cytokines	0.401	0.00358	no	no	no	up	up	no	HC
3-Hydroxy-L-kynurenine+urine	IL-1b	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine+FGF basic-IL-13+IL-1b	Indirect	urine_cometabolism	serum_cytokines	0.401	0.00358	no	no	no	up	up	no	HC
Wautersiella	IL-1b	Wautersiella+Butyricicoccus+d18:1-22:0-SM+blood+FGF basic-IL-13+IL-1b	Indirect	Genus	serum_cytokines	0.289	0.00358	no	no	no	up	up	no	HC
Wautersiella	IL-1b	Wautersiella+Butyricicoccus+d18:1-22:0-SM+blood+FGF basic+IL-17A-IL-1b	Indirect	Genus	serum_cytokines	0.289	0.00358	no	no	no	up	up	no	HC
Blautia	IL-17A	Blautia+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	1.36E-05	0.855	up	dn	dn	no	no	no	HC
Parabacteroides	IL-17A	Parabacteroides+Biosynthesis of amino acids-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	4.19E-05	0.855	no	up	up	no	no	no	HC
Parabacteroides	IL-17A	Parabacteroides-RNA degradation+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	4.19E-05	0.855	no	up	up	no	no	no	HC
Parabacteroides	IL-17A	Parabacteroides-mRNA surveillance pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	4.19E-05	0.855	no	up	up	no	no	no	HC
Dorea	IL-17A	Dorea-VEGF signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Fc epsilon RI signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-18:2-LPC+blood+20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Endocrine resistance+Huntington disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Endocrine resistance+L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Chemical carcinogenesis - receptor activation+L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	"Dorea-Growth hormone synthesis, secretion and action+L-Homocystine+blood+FGF basic+IL-17A"	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Endocrine resistance+mRNA surveillance pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Endocrine resistance+Non-alcoholic fatty liver disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-GnRH signaling pathway+Non-alcoholic fatty liver disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Endocrine resistance+Parkinson disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-GnRH signaling pathway+Parkinson disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Endocrine resistance+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Endocrine resistance+RNA degradation+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Endocrine resistance+Thermogenesis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Thyroid hormone signaling pathway+Viral myocarditis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Chemical carcinogenesis - receptor activation-Viral myocarditis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-16:0-LPC+blood+AA+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Amphetamine addiction-Human papillomavirus infection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Amphetamine addiction-Autoimmune thyroid disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Chemical carcinogenesis - receptor activation-Autoimmune thyroid disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-16:0-LPC+blood+TXB2+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Amphetamine addiction-Allograft rejection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Chemical carcinogenesis - receptor activation-Allograft rejection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Amphetamine addiction-Graft-versus-host disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Chemical carcinogenesis - receptor activation-Graft-versus-host disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea+Legionellosis-Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Amphetamine addiction+Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Chemical carcinogenesis - receptor activation+Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Amphetamine addiction-Viral carcinogenesis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Endocrine resistance+Amyotrophic lateral sclerosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-GnRH signaling pathway+Amyotrophic lateral sclerosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Chemical carcinogenesis - receptor activation-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Dorea	IL-17A	Dorea-Endocrine resistance+Alzheimer disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.00362	0.855	up	no	dn	no	no	no	HC
Faecalibacterium	IL-17A	Faecalibacterium+Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0039	0.855	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-17A	Faecalibacterium-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0039	0.855	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-17A	Faecalibacterium-Staphylococcus aureus infection+Viral myocarditis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0039	0.855	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-17A	Faecalibacterium-Staphylococcus aureus infection+Allograft rejection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0039	0.855	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-17A	Faecalibacterium-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0039	0.855	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-17A	Faecalibacterium+4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0039	0.855	no	dn	dn	no	no	no	HC
Faecalibacterium	IL-17A	Faecalibacterium-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0039	0.855	no	dn	dn	no	no	no	HC
TUDCA+blood	IL-17A	TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.0282	0.855	no	no	dn	no	no	no	HC
TUDCA+blood	IL-17A	TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.0282	0.855	no	no	dn	no	no	no	HC
isocapric acid iso-C6+blood	IL-17A	isocapric acid iso-C6+blood+L-2-Aminobutyric acid+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.0458	0.855	no	no	dn	no	no	no	HC
Bacteroides	IL-17A	Bacteroides-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.000267	0.855	dn	dn	up	no	no	no	HC
Propionic acid+stool	IL-17A	Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.0436	0.855	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-17A	Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.0436	0.855	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-17A	Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.0436	0.855	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-17A	Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.0436	0.855	dn	no	up	no	no	no	HC
Propionic acid+stool	IL-17A	Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.0436	0.855	dn	no	up	no	no	no	HC
[Ruminococcus]	IL-17A	[Ruminococcus]+nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	HC
[Ruminococcus]	IL-17A	[Ruminococcus]+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	HC
[Ruminococcus]	IL-17A	[Ruminococcus]-Hypotaurine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0679	0.855	no	no	dn	no	no	no	HC
GUDCA+blood	IL-17A	GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.0766	0.855	no	no	dn	no	no	no	HC
GUDCA+blood	IL-17A	GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.0766	0.855	no	no	dn	no	no	no	HC
GUDCA+blood	IL-17A	GUDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.0766	0.855	no	no	dn	no	no	no	HC
GUDCA+blood	IL-17A	GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.0766	0.855	no	no	dn	no	no	no	HC
GUDCA+blood	IL-17A	GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.0766	0.855	no	no	dn	no	no	no	HC
GUDCA+blood	IL-17A	GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.0766	0.855	no	no	dn	no	no	no	HC
GUDCA+blood	IL-17A	GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.0766	0.855	no	no	dn	no	no	no	HC
Acetic acid+stool	IL-17A	Acetic acid+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.0656	0.855	dn	no	no	no	no	no	HC
Alistipes	IL-17A	Alistipes+SFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes+20:3/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes+16:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-GDCA+stool-TXB2+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-MAPK signaling pathway-Cell adhesion molecules-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Lipid and atherosclerosis+AA+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Progesterone-mediated oocyte maturation-Allograft rejection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-MAPK signaling pathway-Allograft rejection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Peroxisome-Cardiac muscle contraction+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Peroxisome-Alzheimer disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Progesterone-mediated oocyte maturation-Autoimmune thyroid disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-MAPK signaling pathway-Autoimmune thyroid disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Peroxisome-Prion disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Peroxisome-Huntington disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Progesterone-mediated oocyte maturation-Viral myocarditis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Autophagy - animal-Viral myocarditis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-MAPK signaling pathway-Viral myocarditis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Cholinergic synapse-Viral myocarditis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Peroxisome+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Peroxisome-Non-alcoholic fatty liver disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Peroxisome-Thermogenesis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-NOD-like receptor signaling pathway-Thermogenesis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Autophagy - animal+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-GABAergic synapse+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-FoxO signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Peroxisome+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Autophagy - animal+L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-GABAergic synapse-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-FoxO signaling pathway-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Peroxisome-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-NOD-like receptor signaling pathway-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Olfactory transduction-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Primary immunodeficiency-Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Peroxisome-Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Primary immunodeficiency-20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-16:0/18:2-PI+blood-20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Central carbon metabolism in cancer-20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Peroxisome-20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Olfactory transduction-20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Progesterone-mediated oocyte maturation-Type I diabetes mellitus-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-MAPK signaling pathway-Type I diabetes mellitus-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-GABAergic synapse-Amyotrophic lateral sclerosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Peroxisome-Amyotrophic lateral sclerosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-NOD-like receptor signaling pathway-Amyotrophic lateral sclerosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Progesterone-mediated oocyte maturation-Graft-versus-host disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-MAPK signaling pathway-Graft-versus-host disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-GABAergic synapse-Parkinson disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-Peroxisome-Parkinson disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Alistipes	IL-17A	Alistipes-NOD-like receptor signaling pathway-Parkinson disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.0114	0.855	no	up	no	no	no	no	HC
Butyricimonas	IL-17A	Butyricimonas+Prion disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.17	0.855	no	no	no	no	no	no	HC
Butyricimonas	IL-17A	Butyricimonas+Non-alcoholic fatty liver disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.17	0.855	no	no	no	no	no	no	HC
Butyricimonas	IL-17A	Butyricimonas+Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.17	0.855	no	no	no	no	no	no	HC
Collinsella	IL-17A	Collinsella-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.128	0.855	no	no	no	no	no	no	HC
iso-DCA+stool	IL-17A	iso-DCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.155	0.855	no	no	no	no	no	no	HC
LCA+stool	IL-17A	"LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+FGF basic+IL-17A"	Indirect	stool_bileacids	serum_cytokines	0.314	0.855	no	no	no	no	no	no	HC
LCA+stool	IL-17A	LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.314	0.855	no	no	no	no	no	no	HC
LCA+stool	IL-17A	LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.314	0.855	no	no	no	no	no	no	HC
LCA+stool	IL-17A	LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.314	0.855	no	no	no	no	no	no	HC
LCA+stool	IL-17A	LCA+stool-TCA+stool-20:0+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.314	0.855	no	no	no	no	no	no	HC
LCA+stool	IL-17A	LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.314	0.855	no	no	no	no	no	no	HC
LCA+stool	IL-17A	LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.314	0.855	no	no	no	no	no	no	HC
LCA+stool	IL-17A	LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.314	0.855	no	no	no	no	no	no	HC
LCA+stool	IL-17A	LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.314	0.855	no	no	no	no	no	no	HC
LCA+stool	IL-17A	LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.314	0.855	no	no	no	no	no	no	HC
LCA+stool	IL-17A	LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.314	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia+Systemic lupus erythematosus+Graft-versus-host disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Ribosome-Phagosome-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Ribosome+Cardiac muscle contraction+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Wnt signaling pathway+Retrograde endocannabinoid signaling+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Wnt signaling pathway+Prion disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Ribosome+Prion disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Ribosome-Endocytosis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Wnt signaling pathway+Thermogenesis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Ribosome+Thermogenesis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Wnt signaling pathway+Alzheimer disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Ribosome+Alzheimer disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Ribosome+mRNA surveillance pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Wnt signaling pathway+Amyotrophic lateral sclerosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Ribosome+Amyotrophic lateral sclerosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia+Pertussis+16:0/22:6-PC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia+Systemic lupus erythematosus+Allograft rejection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Ribosome+RNA degradation+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Acetic acid+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Wnt signaling pathway-Cell adhesion molecules-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Ribosome-Cell adhesion molecules-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Wnt signaling pathway-Human papillomavirus infection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia+Pertussis+Human papillomavirus infection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Ribosome-Human papillomavirus infection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Wnt signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Ribosome+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Wnt signaling pathway-Natural killer cell mediated cytotoxicity-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Ribosome-Natural killer cell mediated cytotoxicity-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Wnt signaling pathway+Non-alcoholic fatty liver disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Ribosome+Non-alcoholic fatty liver disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Wnt signaling pathway+Huntington disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Ribosome+Huntington disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Wnt signaling pathway+Parkinson disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Ribosome+Parkinson disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Wnt signaling pathway+Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Coronavirus disease - COVID-19+Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia-Ribosome+Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Akkermansia	IL-17A	Akkermansia+Systemic lupus erythematosus-Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.23	0.855	no	no	no	no	no	no	HC
Bifidobacterium	IL-17A	Bifidobacterium+TXB2+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	HC
Bifidobacterium	IL-17A	Bifidobacterium+AA+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.105	0.855	no	dn	no	no	no	no	HC
Ruminococcus	IL-17A	Ruminococcus+Thermogenesis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.335	0.855	no	no	no	no	no	no	HC
Ruminococcus	IL-17A	Ruminococcus-Endocytosis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.335	0.855	no	no	no	no	no	no	HC
Ruminococcus	IL-17A	Ruminococcus-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.335	0.855	no	no	no	no	no	no	HC
Ruminococcus	IL-17A	Ruminococcus-Biosynthesis of amino acids-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.335	0.855	no	no	no	no	no	no	HC
Ruminococcus	IL-17A	Ruminococcus+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.335	0.855	no	no	no	no	no	no	HC
GCDCA+blood	IL-17A	GCDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.31	0.855	no	no	no	no	no	no	HC
GCDCA+blood	IL-17A	GCDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.31	0.855	no	no	no	no	no	no	HC
GCDCA+blood	IL-17A	GCDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.31	0.855	no	no	no	no	no	no	HC
GCDCA+blood	IL-17A	GCDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.31	0.855	no	no	no	no	no	no	HC
GCDCA+blood	IL-17A	GCDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.31	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]-18:0/22:6-PC+blood-20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]-Glutamatergic synapse-d18:1-22:0-SM+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]+24:0+blood+AA+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]-Aldosterone synthesis and secretion+Alzheimer disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]-18:0/22:6-PC+blood+TXB2+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]-GnRH signaling pathway+Amyotrophic lateral sclerosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]-Aldosterone synthesis and secretion+Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]-Morphine addiction+Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	"[Prevotella]-Growth hormone synthesis, secretion and action+L-Homocystine+blood+FGF basic+IL-17A"	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]-Aldosterone synthesis and secretion+L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]+24:0+blood-L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]-Aldosterone synthesis and secretion+Huntington disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]-Aldosterone synthesis and secretion+Parkinson disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]-GnRH signaling pathway+Parkinson disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]-GnRH signaling pathway+Non-alcoholic fatty liver disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]-Aldosterone synthesis and secretion+Prion disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]-GnRH signaling pathway+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
[Prevotella]	IL-17A	[Prevotella]+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.367	0.855	no	no	no	no	no	no	HC
ACA+blood	IL-17A	ACA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.338	0.855	no	no	no	no	no	no	HC
DCA+stool	IL-17A	DCA+stool-8-HETE+blood+TXB2+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.195	0.855	no	no	no	no	no	no	HC
DCA+stool	IL-17A	DCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.195	0.855	no	no	no	no	no	no	HC
DCA+stool	IL-17A	DCA+stool-20:1-LPA+blood-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.195	0.855	no	no	no	no	no	no	HC
DCA+stool	IL-17A	DCA+stool-8-HETE+blood-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.195	0.855	no	no	no	no	no	no	HC
DCA+stool	IL-17A	DCA+stool-8-HETE+blood+AA+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.195	0.855	no	no	no	no	no	no	HC
DCA+stool	IL-17A	DCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.195	0.855	no	no	no	no	no	no	HC
DCA+stool	IL-17A	DCA+stool-DL-methionine sulfoxide+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.195	0.855	no	no	no	no	no	no	HC
2-hydroxyhippuric acid+urine	IL-17A	2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	urine_cometabolism	serum_cytokines	0.215	0.855	no	no	no	no	no	no	HC
Butyric acid+stool	IL-17A	Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.102	0.855	dn	no	no	no	no	no	HC
4-hydroxybenzoic acid+stool	IL-17A	4-hydroxybenzoic acid+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.0536	0.855	no	dn	no	no	no	no	HC
GCA+blood	IL-17A	GCA+blood+TCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.16	0.855	no	no	no	no	no	no	HC
GCA+blood	IL-17A	GCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.16	0.855	no	no	no	no	no	no	HC
GCA+blood	IL-17A	GCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.16	0.855	no	no	no	no	no	no	HC
GCA+blood	IL-17A	GCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.16	0.855	no	no	no	no	no	no	HC
ACA+stool	IL-17A	ACA+stool+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.417	0.855	no	no	no	no	no	no	HC
ACA+stool	IL-17A	ACA+stool-Acetic acid+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.417	0.855	no	no	no	no	no	no	HC
CDCA+blood	IL-17A	CDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.506	0.855	no	no	no	no	no	no	HC
capric acid C6+blood	IL-17A	capric acid C6+blood-Cystine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.433	0.855	no	no	no	no	no	no	HC
capric acid C6+blood	IL-17A	capric acid C6+blood-Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.433	0.855	no	no	no	no	no	no	HC
capric acid C6+blood	IL-17A	capric acid C6+blood-Cystine+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.433	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-Lysosome+Phagosome-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-18:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-16:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-16:0/20:3-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-18:1/18:1-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-SFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-16:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-18:1/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella+18:0/18:1-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-24:1+blood-d18:1-22:0-SM+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella+12-ketoDCA+blood-AA+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-16:1/16:0-PC+blood+AA+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-16:1/16:1-PC+blood+AA+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Human papillomavirus infection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-Epithelial cell signaling in Helicobacter pylori infection+Viral carcinogenesis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella+Estrogen signaling pathway-Viral carcinogenesis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-Lysosome+Viral carcinogenesis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella+18:1-LPE+blood+L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-18:1/18:1-PC+blood+20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella+18:1-LPE+blood-TXB2+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella+Estrogen signaling pathway-Autoimmune thyroid disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella+Estrogen signaling pathway-Allograft rejection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella+Estrogen signaling pathway-Graft-versus-host disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella+Estrogen signaling pathway-Type I diabetes mellitus-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella+Estrogen signaling pathway-Viral myocarditis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-16:0/16:0-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-Lysosome+Endocytosis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
Prevotella	IL-17A	Prevotella-Lysosome+Natural killer cell mediated cytotoxicity-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.287	0.855	no	no	no	no	no	no	HC
TCA+blood	IL-17A	TCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.339	0.855	no	no	no	no	no	no	HC
iso-DCA+blood	IL-17A	iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.38	0.855	no	no	no	no	no	no	HC
HCA+stool	IL-17A	HCA+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.155	0.855	no	no	no	no	no	no	HC
Roseburia	IL-17A	Roseburia-L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.495	0.855	no	no	no	no	no	no	HC
Roseburia	IL-17A	Roseburia+TXB2+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.495	0.855	no	no	no	no	no	no	HC
12-ketoDCA+stool	IL-17A	12-ketoDCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.505	0.855	no	no	no	no	no	no	HC
12-ketoDCA+stool	IL-17A	12-ketoDCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.505	0.855	no	no	no	no	no	no	HC
GLCA+blood	IL-17A	GLCA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.319	0.855	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-17A	L-Tryptophan+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.557	0.855	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-17A	L-Tryptophan+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.557	0.855	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-17A	L-Tryptophan+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.557	0.855	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-17A	L-Tryptophan+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.557	0.855	no	no	no	no	no	no	HC
L-Tryptophan+stool	IL-17A	L-Tryptophan+stool-12-ketoDCA+blood-AA+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.557	0.855	no	no	no	no	no	no	HC
CA+blood	IL-17A	CA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.606	0.855	no	no	no	no	no	no	HC
GUDCA+stool	IL-17A	GUDCA+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0085	0.855	no	dn	no	no	no	no	HC
GUDCA+stool	IL-17A	GUDCA+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0085	0.855	no	dn	no	no	no	no	HC
L-Phenylalanine+stool	IL-17A	L-Phenylalanine+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.398	0.855	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IL-17A	L-Phenylalanine+stool-12-ketoDCA+blood-AA+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.398	0.855	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IL-17A	L-Phenylalanine+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.398	0.855	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IL-17A	L-Phenylalanine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.398	0.855	no	no	no	no	no	no	HC
L-Phenylalanine+stool	IL-17A	L-Phenylalanine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.398	0.855	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-17A	butyric acid C4+blood+Cystine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.407	0.855	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-17A	butyric acid C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.407	0.855	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-17A	butyric acid C4+blood+Cystine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.407	0.855	no	no	no	no	no	no	HC
butyric acid C4+blood	IL-17A	butyric acid C4+blood+Cystine+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.407	0.855	no	no	no	no	no	no	HC
GCA+stool	IL-17A	GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	HC
GCA+stool	IL-17A	GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	HC
GCA+stool	IL-17A	GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	HC
GCA+stool	IL-17A	GCA+stool+18:0/22:6-PE+blood-20:0+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	HC
GCA+stool	IL-17A	GCA+stool+GDCA+stool-TXB2+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	HC
GCA+stool	IL-17A	GCA+stool-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0809	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus-18:1/18:2-PG+blood+AA+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus-Lysosome+Viral carcinogenesis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Ribosome biogenesis in eukaryotes-Viral carcinogenesis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus-Influenza A+Viral carcinogenesis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+TCA+stool-20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Primary immunodeficiency-20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Central carbon metabolism in cancer-20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Lachnospira-20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus-18:1-LPC+blood+20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus-Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus-18:2-LPC+blood+20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Primary immunodeficiency-Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Lachnospira-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus-18:1-LPC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus-Lysosome+Endocytosis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Ribosome biogenesis in eukaryotes-Endocytosis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus-Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Ribosome biogenesis in eukaryotes-Allograft rejection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus-Influenza A+Allograft rejection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Ribosome biogenesis in eukaryotes-Cell adhesion molecules-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Ribosome biogenesis in eukaryotes-Autoimmune thyroid disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus-Influenza A+Autoimmune thyroid disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Ribosome biogenesis in eukaryotes-Cellular senescence-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus-Lysosome+Natural killer cell mediated cytotoxicity-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Ribosome biogenesis in eukaryotes-Natural killer cell mediated cytotoxicity-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Ribosome biogenesis in eukaryotes-Graft-versus-host disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus-Influenza A+Graft-versus-host disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Ribosome biogenesis in eukaryotes-Human papillomavirus infection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus-Influenza A+Human papillomavirus infection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Ribosome biogenesis in eukaryotes+mRNA surveillance pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus-Lysosome+Phagosome-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Ribosome biogenesis in eukaryotes-Phagosome-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Ribosome biogenesis in eukaryotes+RNA degradation+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Ribosome biogenesis in eukaryotes-Type I diabetes mellitus-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus+Ribosome biogenesis in eukaryotes-Viral myocarditis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Coprococcus	IL-17A	Coprococcus-Influenza A+Viral myocarditis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.612	0.855	no	no	no	no	no	no	HC
Oscillospira	IL-17A	Oscillospira-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	HC
Oscillospira	IL-17A	Oscillospira+L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.62	0.855	no	no	no	no	no	no	HC
HCA+blood	IL-17A	HCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.544	0.855	no	no	no	no	no	no	HC
iso-LCA+stool	IL-17A	iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.72	0.855	no	no	no	no	no	no	HC
iso-LCA+stool	IL-17A	iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.72	0.855	no	no	no	no	no	no	HC
iso-LCA+stool	IL-17A	iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.72	0.855	no	no	no	no	no	no	HC
iso-LCA+stool	IL-17A	iso-LCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.72	0.855	no	no	no	no	no	no	HC
iso-LCA+stool	IL-17A	iso-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.72	0.855	no	no	no	no	no	no	HC
iso-LCA+stool	IL-17A	iso-LCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.72	0.855	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-17A	2-methyl-butyric acid m-C4+blood+20:1+blood-22:6n3+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.262	0.855	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-17A	2-methyl-butyric acid m-C4+blood+iso-heptanoic acid C7+blood-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.262	0.855	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-17A	2-methyl-butyric acid m-C4+blood+decanoic acid C10+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.262	0.855	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-17A	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.262	0.855	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-17A	2-methyl-butyric acid m-C4+blood+lauric acid C12+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.262	0.855	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-17A	2-methyl-butyric acid m-C4+blood-22:2-LPA+blood-d18:0-24:1-SM+blood+d18:1-22:0-SM+blood+FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.262	0.855	no	no	no	no	no	no	HC
2-methyl-butyric acid m-C4+blood	IL-17A	2-methyl-butyric acid m-C4+blood+20:1+blood+20:1-LPC+blood-TXB2+blood-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.262	0.855	no	no	no	no	no	no	HC
DCA+blood	IL-17A	DCA+blood+GUDCA+blood-PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.122	0.855	no	no	no	no	no	no	HC
DCA+blood	IL-17A	DCA+blood+GUDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.122	0.855	no	no	no	no	no	no	HC
DCA+blood	IL-17A	DCA+blood+GUDCA+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.122	0.855	no	no	no	no	no	no	HC
DCA+blood	IL-17A	DCA+blood+GUDCA+blood-iso-DCA+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.122	0.855	no	no	no	no	no	no	HC
DCA+blood	IL-17A	DCA+blood+GUDCA+blood-UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.122	0.855	no	no	no	no	no	no	HC
DCA+blood	IL-17A	DCA+blood+GUDCA+blood+TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.122	0.855	no	no	no	no	no	no	HC
DCA+blood	IL-17A	"DCA+blood-n6+blood+3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A"	Indirect	serum_bileacids	serum_cytokines	0.122	0.855	no	no	no	no	no	no	HC
DCA+blood	IL-17A	DCA+blood+GUDCA+blood+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.122	0.855	no	no	no	no	no	no	HC
3-(3-Hydroxyphenyl)propanoic acid+stool	IL-17A	3-(3-Hydroxyphenyl)propanoic acid+stool+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.33	0.855	no	no	no	no	no	no	HC
"3-(3,4-dihydroxyphenyl)propionic acid+urine"	IL-17A	"3-(3,4-dihydroxyphenyl)propionic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A"	Indirect	urine_cometabolism	serum_cytokines	0.0125	0.855	up	up	no	no	no	no	HC
GLCA+stool	IL-17A	GLCA+stool-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.617	0.855	no	no	no	no	no	no	HC
GLCA+stool	IL-17A	GLCA+stool-iso-LCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.617	0.855	no	no	no	no	no	no	HC
GLCA+stool	IL-17A	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.617	0.855	no	no	no	no	no	no	HC
GLCA+stool	IL-17A	GLCA+stool-LCA+stool+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.617	0.855	no	no	no	no	no	no	HC
GLCA+stool	IL-17A	GLCA+stool-iso-LCA+stool-18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.617	0.855	no	no	no	no	no	no	HC
GLCA+stool	IL-17A	GLCA+stool-LCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.617	0.855	no	no	no	no	no	no	HC
GLCA+stool	IL-17A	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.617	0.855	no	no	no	no	no	no	HC
GLCA+stool	IL-17A	GLCA+stool-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.617	0.855	no	no	no	no	no	no	HC
GLCA+stool	IL-17A	GLCA+stool-iso-LCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.617	0.855	no	no	no	no	no	no	HC
GLCA+stool	IL-17A	"GLCA+stool-LCA+stool+9,10-EPOME+blood+d18:1-22:0-SM+blood+FGF basic+IL-17A"	Indirect	stool_bileacids	serum_cytokines	0.617	0.855	no	no	no	no	no	no	HC
GLCA+stool	IL-17A	GLCA+stool-iso-LCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.617	0.855	no	no	no	no	no	no	HC
GLCA+stool	IL-17A	GLCA+stool-iso-LCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.617	0.855	no	no	no	no	no	no	HC
GLCA+stool	IL-17A	GLCA+stool-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.617	0.855	no	no	no	no	no	no	HC
GLCA+stool	IL-17A	GLCA+stool-iso-LCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.617	0.855	no	no	no	no	no	no	HC
GLCA+stool	IL-17A	GLCA+stool-LCA+stool-TCA+stool-20:0+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.617	0.855	no	no	no	no	no	no	HC
GLCA+stool	IL-17A	GLCA+stool-LCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.617	0.855	no	no	no	no	no	no	HC
GLCA+stool	IL-17A	GLCA+stool-LCA+stool+16:0/18:2-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.617	0.855	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-17A	Indole-3-Acetic acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.304	0.855	no	no	no	no	no	no	HC
Indole-3-Acetic acid+stool	IL-17A	Indole-3-Acetic acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.304	0.855	no	no	no	no	no	no	HC
TCA+stool	IL-17A	TCA+stool-20:0+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.458	0.855	no	no	no	no	no	no	HC
HDCA+stool	IL-17A	HDCA+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	HC
HDCA+stool	IL-17A	HDCA+stool+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	HC
HDCA+stool	IL-17A	HDCA+stool-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	HC
HDCA+stool	IL-17A	HDCA+stool-16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	HC
HDCA+stool	IL-17A	HDCA+stool+20:3/16:0-PC+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	HC
HDCA+stool	IL-17A	HDCA+stool+16:0/18:1-PC+blood+16:0/22:6-PC+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	HC
HDCA+stool	IL-17A	HDCA+stool+16:0/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	HC
HDCA+stool	IL-17A	HDCA+stool+16:0/18:1-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	HC
HDCA+stool	IL-17A	HDCA+stool-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	HC
HDCA+stool	IL-17A	HDCA+stool+18:0/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	HC
HDCA+stool	IL-17A	HDCA+stool+20:3/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.176	0.855	no	no	no	no	no	no	HC
Lachnospira	IL-17A	Lachnospira-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.279	0.855	no	no	no	no	no	no	HC
Lachnospira	IL-17A	Lachnospira-20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.279	0.855	no	no	no	no	no	no	HC
isobutyric acid C4+blood	IL-17A	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.0151	0.855	up	up	no	no	no	no	HC
isobutyric acid C4+blood	IL-17A	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.0151	0.855	up	up	no	no	no	no	HC
isobutyric acid C4+blood	IL-17A	isobutyric acid C4+blood+L-Isoleucine+blood+L-Lysine+blood+L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.0151	0.855	up	up	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool-9-HODE+blood-L-Ornithine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood+TXB2+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood-TXB2+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool-Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool-Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool+18:0/20:5-PC+blood+18:0/22:6-PC+blood-20:0+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool-Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool-9-HODE+blood+GPC+blood-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool+18:0/20:5-PC+blood-18:1-LPE+blood+L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool+18:0/20:5-PC+blood-20:0-LPE+blood+d18:1-22:0-SM+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool+18:0/20:5-PC+blood+18:2/20:4-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool+18:0/20:5-PC+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool+18:0/20:5-PC+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool+18:0/20:5-PC+blood+18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool+18:0/20:5-PC+blood+18:1/18:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
GCDCA+stool	IL-17A	GCDCA+stool+18:0/20:5-PC+blood-Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.0471	0.855	no	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool+GCA+stool-L-Methionine+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-Propionic acid+stool+Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool+GCA+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool+GCA+stool+16:0/18:0-PS+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool+GCA+stool+GDCA+stool-TXB2+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool-Propionic acid+stool+16:0/18:2-PI+blood-20:0+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	HC
5-Hydroxytryptamine+stool	IL-17A	5-Hydroxytryptamine+stool+GCA+stool+18:0/22:6-PE+blood-20:0+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.00862	0.855	dn	dn	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Endocrine resistance+Huntington disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Long-term depression+Huntington disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Pancreatic secretion+Huntington disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Aldosterone synthesis and secretion+Huntington disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Cushing syndrome+Huntington disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Endocrine resistance+L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Long-term depression+L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Pancreatic secretion+L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Aldosterone synthesis and secretion+L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter+Arginine and proline metabolism+Biosynthesis of amino acids-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Endocrine resistance+mRNA surveillance pathway+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Long-term depression-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Pancreatic secretion-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Long-term depression+Prion disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Pancreatic secretion+Prion disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Aldosterone synthesis and secretion+Prion disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Endocrine resistance+Non-alcoholic fatty liver disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Long-term depression+Non-alcoholic fatty liver disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Aldosterone synthesis and secretion+Non-alcoholic fatty liver disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Endocrine resistance+Parkinson disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Long-term depression+Parkinson disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter+Arginine and proline metabolism-Parkinson disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Pancreatic secretion+Parkinson disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Aldosterone synthesis and secretion+Parkinson disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Cushing syndrome+Parkinson disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Endocrine resistance+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Long-term depression+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter+Arginine and proline metabolism-Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Pancreatic secretion+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Aldosterone synthesis and secretion+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Cushing syndrome+Pathways of neurodegeneration - multiple diseases+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Endocrine resistance+RNA degradation+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter+Arginine and proline metabolism-RNA degradation+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Endocrine resistance+Alzheimer disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Long-term depression+Alzheimer disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Pancreatic secretion+Alzheimer disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Aldosterone synthesis and secretion+Alzheimer disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Cushing syndrome+Alzheimer disease+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Phospholipase D signaling pathway+AGE-RAGE signaling pathway in diabetic complications-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Endocrine resistance+Thermogenesis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter+Arginine and proline metabolism-Thermogenesis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Endocrine resistance+Amyotrophic lateral sclerosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Long-term depression+Amyotrophic lateral sclerosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter+Arginine and proline metabolism-Amyotrophic lateral sclerosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Pancreatic secretion+Amyotrophic lateral sclerosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Aldosterone synthesis and secretion+Amyotrophic lateral sclerosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Cushing syndrome+Amyotrophic lateral sclerosis+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Pancreatic secretion+20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Morphine addiction+Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Long-term depression+Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Pancreatic secretion+Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Aldosterone synthesis and secretion+Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Odoribacter	IL-17A	Odoribacter-Cushing syndrome+Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.798	0.855	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-17A	Isobutyric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.408	0.855	no	no	no	no	no	no	HC
Isobutyric acid+stool	IL-17A	Isobutyric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.408	0.855	no	no	no	no	no	no	HC
Kynurenic acid+stool	IL-17A	Kynurenic acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.037	0.855	dn	dn	no	no	no	no	HC
L-Tryptophan+urine	IL-17A	L-Tryptophan+urine+FGF basic+IL-17A	Indirect	urine_cometabolism	serum_cytokines	0.226	0.855	no	no	no	no	no	no	HC
Eggerthella	IL-17A	Eggerthella+Bacteroides-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.912	0.855	no	no	no	no	no	no	HC
Anaerotruncus	IL-17A	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.904	0.855	no	no	no	no	no	no	HC
Anaerotruncus	IL-17A	Anaerotruncus-Gemmiger-Tuberculosis+Graft-versus-host disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.904	0.855	no	no	no	no	no	no	HC
Anaerotruncus	IL-17A	Anaerotruncus-Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.904	0.855	no	no	no	no	no	no	HC
Anaerotruncus	IL-17A	Anaerotruncus-Gemmiger-Tuberculosis-Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.904	0.855	no	no	no	no	no	no	HC
Anaerotruncus	IL-17A	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Viral myocarditis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.904	0.855	no	no	no	no	no	no	HC
Anaerotruncus	IL-17A	Anaerotruncus-Gemmiger-Tuberculosis+Viral myocarditis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.904	0.855	no	no	no	no	no	no	HC
Anaerotruncus	IL-17A	Anaerotruncus-Gemmiger-GPC+blood-L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.904	0.855	no	no	no	no	no	no	HC
Anaerotruncus	IL-17A	Anaerotruncus-Gemmiger-20:1-LPA+blood-L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.904	0.855	no	no	no	no	no	no	HC
Anaerotruncus	IL-17A	Anaerotruncus-Gemmiger-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.904	0.855	no	no	no	no	no	no	HC
Anaerotruncus	IL-17A	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Allograft rejection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.904	0.855	no	no	no	no	no	no	HC
Anaerotruncus	IL-17A	Anaerotruncus-Gemmiger-Tuberculosis+Allograft rejection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.904	0.855	no	no	no	no	no	no	HC
Anaerotruncus	IL-17A	Anaerotruncus-Gemmiger-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.904	0.855	no	no	no	no	no	no	HC
Anaerotruncus	IL-17A	Anaerotruncus-Gemmiger-Tuberculosis+Autoimmune thyroid disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.904	0.855	no	no	no	no	no	no	HC
Anaerotruncus	IL-17A	Anaerotruncus-Gemmiger+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.904	0.855	no	no	no	no	no	no	HC
Anaerotruncus	IL-17A	Anaerotruncus-Gemmiger-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.904	0.855	no	no	no	no	no	no	HC
Anaerostipes	IL-17A	Anaerostipes-20:0+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.568	0.855	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-17A	Isovaleric acid+stool-nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.343	0.855	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-17A	Isovaleric acid+stool+Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.343	0.855	no	no	no	no	no	no	HC
Isovaleric acid+stool	IL-17A	Isovaleric acid+stool+Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_scfa	serum_cytokines	0.343	0.855	no	no	no	no	no	no	HC
Paraprevotella	IL-17A	Paraprevotella-L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	HC
Paraprevotella	IL-17A	Paraprevotella+AA+blood-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.118	0.855	no	no	no	no	no	no	HC
Homovanillic acid+urine	IL-17A	Homovanillic acid+urine-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	urine_cometabolism	serum_cytokines	0.45	0.855	no	no	no	no	no	no	HC
Homovanillic acid+urine	IL-17A	Homovanillic acid+urine+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	urine_cometabolism	serum_cytokines	0.45	0.855	no	no	no	no	no	no	HC
TDCA+blood	IL-17A	TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.155	0.855	no	up	no	no	no	no	HC
iso-LCA+blood	IL-17A	iso-LCA+blood-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.507	0.855	no	no	no	no	no	no	HC
iso-LCA+blood	IL-17A	iso-LCA+blood-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.507	0.855	no	no	no	no	no	no	HC
iso-LCA+blood	IL-17A	iso-LCA+blood+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.507	0.855	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IL-17A	¦Ø-MCA+stool-Butyric acid+stool-d18:1-22:0-SM+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.919	0.855	no	no	no	no	no	no	HC
¦Ø-MCA+stool	IL-17A	¦Ø-MCA+stool-Acetic acid+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.919	0.855	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-17A	Phenylacetic acid+stool+20:0+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.785	0.855	no	no	no	no	no	no	HC
Phenylacetic acid+stool	IL-17A	Phenylacetic acid+stool-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.785	0.855	no	no	no	no	no	no	HC
Gemmiger	IL-17A	Gemmiger-Staphylococcus aureus infection+Graft-versus-host disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	HC
Gemmiger	IL-17A	Gemmiger-Tuberculosis+Graft-versus-host disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	HC
Gemmiger	IL-17A	Gemmiger-Staphylococcus aureus infection-Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	HC
Gemmiger	IL-17A	Gemmiger-Tuberculosis-Diabetic cardiomyopathy+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	HC
Gemmiger	IL-17A	Gemmiger-Staphylococcus aureus infection+Viral myocarditis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	HC
Gemmiger	IL-17A	Gemmiger-Tuberculosis+Viral myocarditis-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	HC
Gemmiger	IL-17A	Gemmiger-GPC+blood-L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	HC
Gemmiger	IL-17A	Gemmiger-20:1-LPA+blood-L-Homocystine+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	HC
Gemmiger	IL-17A	Gemmiger-TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	HC
Gemmiger	IL-17A	Gemmiger-Staphylococcus aureus infection+Allograft rejection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	HC
Gemmiger	IL-17A	Gemmiger-Tuberculosis+Allograft rejection-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	HC
Gemmiger	IL-17A	Gemmiger-Staphylococcus aureus infection+Autoimmune thyroid disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	HC
Gemmiger	IL-17A	Gemmiger-Tuberculosis+Autoimmune thyroid disease-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	HC
Gemmiger	IL-17A	Gemmiger+LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	HC
Gemmiger	IL-17A	Gemmiger-TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.595	0.855	no	no	no	no	no	no	HC
GDCA+stool	IL-17A	GDCA+stool-TXB2+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.656	0.855	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-17A	L-Tyrosine+stool+18:1/18:1-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.44	0.855	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-17A	L-Tyrosine+stool+16:0/22:6-PE+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.44	0.855	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-17A	L-Tyrosine+stool+PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.44	0.855	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-17A	L-Tyrosine+stool+20:1-LPA+blood-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.44	0.855	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-17A	L-Tyrosine+stool+8-HETE+blood-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.44	0.855	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-17A	L-Tyrosine+stool-12-ketoDCA+blood-AA+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.44	0.855	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-17A	L-Tyrosine+stool+8-HETE+blood+AA+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.44	0.855	no	no	no	no	no	no	HC
L-Tyrosine+stool	IL-17A	L-Tyrosine+stool+8-HETE+blood+TXB2+blood-FGF basic+IL-17A	Indirect	stool_cometabolism	serum_cytokines	0.44	0.855	no	no	no	no	no	no	HC
CDCA+stool	IL-17A	CDCA+stool+18:3n3+blood+AA+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.663	0.855	no	no	no	no	no	no	HC
CDCA+stool	IL-17A	CDCA+stool+TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.663	0.855	no	no	no	no	no	no	HC
CDCA+stool	IL-17A	CDCA+stool+nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.663	0.855	no	no	no	no	no	no	HC
CDCA+stool	IL-17A	CDCA+stool+HCA+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.663	0.855	no	no	no	no	no	no	HC
CDCA+stool	IL-17A	CDCA+stool+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.663	0.855	no	no	no	no	no	no	HC
CDCA+stool	IL-17A	CDCA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.663	0.855	no	no	no	no	no	no	HC
CDCA+stool	IL-17A	CDCA+stool-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.663	0.855	no	no	no	no	no	no	HC
CA+stool	IL-17A	CA+stool+nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.827	0.855	no	no	no	no	no	no	HC
CA+stool	IL-17A	CA+stool+HCA+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.827	0.855	no	no	no	no	no	no	HC
CA+stool	IL-17A	CA+stool-ACA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.827	0.855	no	no	no	no	no	no	HC
CA+stool	IL-17A	CA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.827	0.855	no	no	no	no	no	no	HC
CA+stool	IL-17A	CA+stool+TUDCA+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.827	0.855	no	no	no	no	no	no	HC
CA+stool	IL-17A	CA+stool-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.827	0.855	no	no	no	no	no	no	HC
CA+stool	IL-17A	CA+stool+GDCA+stool-TXB2+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.827	0.855	no	no	no	no	no	no	HC
CA+stool	IL-17A	CA+stool+TUDCA+blood-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.827	0.855	no	no	no	no	no	no	HC
CA+stool	IL-17A	CA+stool-18:1/16:0-PC+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.827	0.855	no	no	no	no	no	no	HC
HDCA+blood	IL-17A	HDCA+blood+L-Aspartic acid+blood+TXB2+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.483	0.855	no	no	no	no	no	no	HC
HDCA+blood	IL-17A	HDCA+blood+UFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.483	0.855	no	no	no	no	no	no	HC
HDCA+blood	IL-17A	HDCA+blood+SFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.483	0.855	no	no	no	no	no	no	HC
HDCA+blood	IL-17A	HDCA+blood+PUFA%+blood+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.483	0.855	no	no	no	no	no	no	HC
UDCA+stool	IL-17A	UDCA+stool+16:0/18:3-PC+blood+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.266	0.855	no	no	no	no	no	no	HC
UDCA+stool	IL-17A	UDCA+stool+18:3n3+blood+AA+blood-FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.266	0.855	no	no	no	no	no	no	HC
LCA+blood	IL-17A	LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.884	0.855	no	no	no	no	no	no	HC
nutriCA+stool	IL-17A	nutriCA+stool-L-Homocystine+blood+FGF basic+IL-17A	Indirect	stool_bileacids	serum_cytokines	0.481	0.855	no	no	no	no	no	no	HC
GDCA+blood	IL-17A	GDCA+blood+TDCA+blood+2-hydroxyhippuric acid+urine-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.632	0.855	no	no	no	no	no	no	HC
P-hydroxyhippuric acid+urine	IL-17A	P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	urine_cometabolism	serum_cytokines	0.436	0.855	no	no	no	no	no	no	HC
acetic acid C2+blood	IL-17A	acetic acid C2+blood-LCA+blood-P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.000193	0.855	up	dn	no	no	no	no	HC
isovaleric acid iso-C5+blood	IL-17A	isovaleric acid iso-C5+blood+Sarcosine+blood-L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	serum_scfa	serum_cytokines	0.117	0.855	no	no	no	no	no	no	HC
L-Phenylalanine+urine	IL-17A	L-Phenylalanine+urine+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	urine_cometabolism	serum_cytokines	0.0908	0.855	no	up	no	no	no	no	HC
Clostridium	IL-17A	Clostridium+P-hydroxyhippuric acid+urine-FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	HC
Clostridium	IL-17A	Clostridium-L-Tryptophan+urine+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.925	0.855	no	no	no	no	no	no	HC
12-ketoDCA+blood	IL-17A	12-ketoDCA+blood-AA+blood-FGF basic+IL-17A	Indirect	serum_bileacids	serum_cytokines	0.517	0.855	no	no	no	no	no	no	HC
Butyricicoccus	IL-17A	Butyricicoccus+d18:1-22:0-SM+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.852	0.855	no	no	no	no	no	no	HC
3-Hydroxy-L-kynurenine+urine	IL-17A	3-Hydroxy-L-kynurenine+urine+L-Tryptophan+urine+FGF basic+IL-17A	Indirect	urine_cometabolism	serum_cytokines	0.401	0.855	no	no	no	no	no	no	HC
Wautersiella	IL-17A	Wautersiella+Butyricicoccus+d18:1-22:0-SM+blood+FGF basic+IL-17A	Indirect	Genus	serum_cytokines	0.289	0.855	no	no	no	no	no	no	HC