For linux/Unix user: please run the script file named "buid" to install the program. All resultant executable files will be generated in the package "bin". Please follow below instructions to run the program: 1) ensure that MED2, TRITisa.exe, settings, EDPCenters.txt and EDPCentersGC.txt are saved in the same directory, say "bin"; 2) move your genomic file in FastA format to the, say "bin" directory; 3) type in the console the instruction "./MED fna_file". Predictions will be saved in the same directory, say "bin".