On April 9, 2025, Prof. Charles Cox from the Victor Chang Cardiac Research Institute was invited by Prof. Chen Song to deliver a CQB seminar titled "A new family of PIEZO channel auxiliary subunits". He introduced his team's discovery of MyoD-family inhibitor proteins (MDFIC and MDFI) as auxiliary subunits of PIEZO1/2 channels. Cryo-EM studies revealed their direct binding to PIEZO2's pore module. Prof. Charles Cox provides extensive data, highlighting their role as key regulators integrating mechanical signals into transcriptional pathways.
