A huge congratulations to Ruihan on winning the National Scholarship! Congratulations!!

Congratulations to Jingze, Lingfeng, and Zefeng on successfully passing their mid-term assessments! This important milestone brings them one step closer to earning their PhD degrees. Well done, and keep up the excellent work!

Ruihan's AMPainter work has been published in Adv. Sci. (Link). AMPainter is a powerful design model for 'painting' the antimicrobial potency on any given peptide sequence, based on the strategy of virtual directed evolution and deep reinforcement learning. The wet lab validations of the designed AMPs were conducted in our lab with Qiushi's participation. Meanwhile, our patents on the model and peptides have been granted recently. Congratulations!

Congratulations to Qiushi and Jun on successfully passing their PhD qualifying exams! They will now continue their research in our group as a formal PhD candidate. Congratulations again！

We are delighted to welcome Qianli and Jiajun to our group, following the successful completion of their rotations. Qianli will focus on MD simulations of the Sec system, and Jiajun will work on predicting protein multiple conformations. Their diverse expertise will be a valuable asset to our group. Welcome!

Dr. Chen Song was invited to deliver a talk at the 8^th National Conference on Statistical Physics and Complex Systems, which was held in Ningbo on July 30, 2025. He presented our recently published work on the Ca²⁺ permeation and selectivity mechanisms of voltage-gated calcium ion channels.

Lingfeng has won the President's Scholarship of Peking University. Congratulations!

From June 13th to 15th, 2025, our group actively participated in the 3rd National Conference on Biomolecular Structure Prediction and Modeling, held in Changchun, China. Prof. Chen SONG, along with Zefeng, Yiechang, and Lei, were honored with invitations to give talks to present our group's latest research. Congratulations to Jingze, Lingfeng, Qingyang, and Song for winning the poster award. Beyond the academic exchange, the conference provided a heartwarming reunion with former group members Hua, Dali, Yang, Jiaxuan, and Song. It was a joyous occasion to reconnect, reminisce, and celebrate our shared journey in advancing biomolecular science.

Lingfeng's work on the ion permeation and selectivity mechanisms of the voltage-gated calcium ion channel Ca_V1 has been published in PNAS (Link). In this work, Lingfeng showed that the three-ion knock-on mechanism not only enables the efficient calcium ion permeation but also helps to generate the valence selectivity because it is harder for sodium ions to get involved in the knock-on. Congratulations!

Dr. Chen Song was invited to give a talk at the "2025 Hong Kong Symposium on Molecular Modeling and Simulation" on May 24, an event organized by Dr. Yi Wang at The Chinese University of Hong Kong and co-chaired by Dr. Song. Zhongjie's recent work on improved anisotropic network models for membrane proteins and mechanosensitive ion channels was presented. A draft of the work has been posted on bioRxiv as well: https://doi.org/10.1101/2025.05.22.654704.