Education:

2014-2018  B.E. in Pharmaceutical Engineering, Tianjin University

2018-2023  Ph.D. in Integrated Life Sciences, Peking University

Research interests:

My research focuses on the design of biologically inspired AI architectures and the development of foundational digital twin models spanning scales from single cells to whole individuals. With a particular emphasis on aging, I aim to uncover cross-scale spatiotemporal dynamics, discover and design targeted interventions, and advance precision health management.

Academic experiences:

2023-2026  Postdoctoral Researcher, Center for Quantitative Biology, Peking University

2026  Research Assistant, Jing-Dong J. Han Laboratory, Center for Quantitative Biology, Peking University

Selected publications:

1. Jiawei Chen^, Ya Ren^, Yong Zhou^, Ziyang Wang^, Jiyang Li, Xiaoxiao Guo, Hao Xu, Yiyang Wang, Huiru Tang and Jing-Dong J. Han*. Multi-modality profiling identifies Neisseria flavescens as a central geroprotective oral commensal in humans. Nature Aging, Sep 2026.  

2. Jiawei Chen^, Ya Ren^, Yong Zhou^, Ziyang Wang^, Kehang Mao, Zhengqing Yu, Jiyang Li, Xiaoxiao Gu, Hao Xu, Yiyang Wang , Yi Wang, Bo Pang, Hongxiao Liu, Huiru Tang, Jing-Dong J. Han*. A generative AI framework unifies human multi-omics to model aging, metabolic health, and intervention response. Cell Metabolism, Apr 2026.

3. Hongming Zhu^, Jiawei Chen^, Kangping Liu^, Lei Gao, Haiyan Wu, Liangliang Ma,Jieru Zhou, Zhongmin Liu*, Jing-Dong J. Han*. Human PBMC scRNA-seq–based aging clocks reveal ribosome to inflammation balance as a single-cell aging hallmark and super longevity. Science Advances, Jun 2023.  

4. Jiawei Chen^, Hao Xu^, Wanyu Tao, Zhaoxiong Chen, Yuxuan Zhao and Jing-Dong J. Han*. Transformer for one stop interpretable cell type annotation. Nature Communications, Jan 2023.  

5. Jiawei Chen^, Quanlong Jiang^, Xian Xia^, Kangping Liu^, Zhengqing Yu, Wanyu Tao, Wenxuan Gong and Jing-Dong J. Han*. Individual variation of the SARS-CoV-2 receptor ACE2 gene expression and regulation. Aging Cell, Jun 2020.