Publications

Zhi-Bo Zhang, Qiu-Yue Wang, Yu-Xi Ke, Shi-Yu Liu, Jian-Qi Ju, Wendell A. Lim, Chao Tang, Wei, P.*. Design of Tunable Oscillatory Dynamics in a Synthetic NF-kappaB Signaling Circuit. Cell Systems 2017; 5,1-11.

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Amir Mitchell, Wei, P.*, Wendell A. Lim*. Oscillatory stress stimulation uncovers an Achilles’ heel of the yeast MAPK signaling network. Science 2015; 350, 1379-1383. (*co-corr. author)

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Martin, H., Shales, M., Fernandez-Pinar, P., Wei, P., Molina, M., Fiedler, D., Shokat, K. M., Beltrao, P., Lim, W., Krogan, N. J. Differential genetic interactions of yeast stress response MAPK pathways. Molecular systems biology 2015; 11, 800.

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Xi, D., Wei, P., Zhang, C. & Lai, L. The minimal alpha-crystallin domain of Mj Hsp16.5 is functional at non-heat-shock conditions. Proteins 2014; 82, 1156-1167.

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Wei, P.*, Wong, W.W.*, Park, J.S., Corcoran, E. E., Peisajovich, S. G., Onuffer, J, J., Weiss, A., Lim, W.A. Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells. Nature 2012; 488, 384-388. (*co-first author)

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Peisajovich, S.G., Garbarino, J.E., Wei, P., Lim, W.A. Rapid diversification of cell signaling phenotypes by modular domain recombination. Science 2010; 328, 368-372

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Li, C., Qi, Y., Teng, X., Yang, Z., Wei, P., Zhang, C., Tan, L., Zhou, L., Liu, Y., Lai, L. Maturation mechanism of severe acute respiratory syndrome (SARS) coronavirus 3C-like proteinase. J Biol Chem. 2010; Sep 3;285(36):28134-40.

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Wei, P., Li, C., Zhou, L., Liu Y., Lai, L. Substrate Binding and Homo-Dimerization of SARS 3CL Proteinase are Mutual Allosteric Effectors [J]. Acta Phys. Chim. Sin., 2010; 26(04): 1093-1098.

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Liang H., Chen, H., Fan, F., Wei, P., Guo, X., Jin, C., Zeng, C., Tang, C., Lai, L. De novo design of a beta alpha beta motif. Angew Chem Int Ed Engl. 2009; 48(18):3301-3.

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Zhou, L., Fang, C., Wei, P., Liu S., Liu, Y., Lai, L. Chemically induced dimerization of human nonpancreatic secretory phospholipase A2 by bis-indole derivatives. J Med Chem. 2008; 51(12):3360-6.

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Cao, A., Wang, Z., Wei, P., Xu, F., Cao, J., Lai, L. Preheating induced homogeneity of the small heat shock protein from Methanococcus jannaschii. Biochimica et Biophysica Acta 2008; 1784: 489-495.

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Chen, H.*, Wei, P.*, Huang, C., Tan, L., Liu, Y., Lai, L. Only one protomer is active in the dimer of SARS 3C-like proteinase. J. Biol. Chem. 2006; 281: 13894-13898. (*co-first author)

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Wei, P.*, Fan, K.*, Chen, H., Ma, L., Huang, C., Tan, L., Xi, D., Li, C., Liu, Y., Cao, A., Lai, L. The N-terminal octapeptide acts as a dimerization inhibitor of SARS coronavirus 3C-like proteinase. Biochem. Biophys. Res. Commun. 2006; 339: 865-872. (*co-first author)

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Lai, L., Han, X., Chen, H., Wei, P., Huang, C., Liu, S., Fan, K., Zhou, L., Liu, Z., Pei, J., Liu, Y. Quaternary structure, substrate selectivity and inhibitor design for SARS 3C-like proteinase. Curr. Pharm. Des. 2006; 12: 4555-4564.

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Zhou, L., Liu, Y., Zhang W., Wei, P., Huang, C., Pei, J., Yuan, Y., Lai, L. Isatin compounds as noncovalent SARS coronavirus 3C-like protease inhibitors. J. Med. Chem. 2006; 49: 3440-3443.

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Ding, L., Zhang, X., Wei, P., Fan, K., Lai, L. The interaction between severe acute respiratory syndrome coronavirus 3C-like proteinase and a dimeric inhibitor by capillary electrophoresis. Anal. Biochem. 2005; 343: 159-165.

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Liu, Z., Huang, C., Fan, K., Wei, P., Chen, H., Liu, S., Pei, J., Shi, L., Li, B., Yang, K., Liu, Y., Lai, L. Virtual screening of novel noncovalent inhibitors for SARS-CoV 3C-like proteinase. J. Chem. Inf. Model. 2005; 45: 10-17.

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Fan, K., Ma, L., Han, X., Liang, H., Wei, P., Liu, Y., Lai, L., The substrate specificity of SARS coronavirus 3C-like proteinase. Biochem. Biophys. Res. Commun. 2005; 329: 934-940.

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Huang, C., Wei, P., Fan, K., Liu, Y., Lai, L. 3C-like proteinase from SARS coronavirus catalyzes substrate hydrolysis by a general base mechanism. Biochemistry 2004; 43: 4568-4574.

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Fan, K.*, Wei, P.*, Feng, Q., Chen, S., Huang, C., Ma, L., Lai, B., Pei, J., Liu, Y., Chen, J., Lai, L. Biosynthesis, purification, and substrate specificity of severe acute respiratory syndrome coronavirus 3C-like proteinase. J. Biol. Chem. 2004; 279: 1637-1642. (*co-first author)

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