Introduction
The ABVFCD database has collected 190,539 sequences of virulence genes of 1,942 strains of Acinetobacter baumannii which were collected from 25 provinces in mainland China. By classifying these virulence gene sequences, we aim to provide support for the spatiotemporal evolution research of Acinetobacter baumannii virulence genes. The current classification information in this database includes the spationtemporal distribution of virulence genes nationwide and the clinical status of these genes. In the future, we will incorporate classification information of potential unknown pathogenic factors predicted using host-bacteria and protein-protein interaction algorithms.
We classfied virulence factors by Year, Province, Humidity and Infection. You can get all the information about category from here: ABVF_Conclusion.xls
Classify & Datasets download
In each .faa file, the first sequence is the protein sequence referenced from ABVF database, and the remaining sequences are from our samples.
Each .faa is named after the gene of the virulence factor in the ABVF database. In the process of processing the sequences, we prescribe:
(1) "/" in the gene name is replaced with "^" giving that the file name is not allowed to include "/".
(2) For different sequence files of the same gene, we use _2, _3, etc. at the end of the file name to distinguish them.
Spatiotemporal Distribution
Year
ABVF_Year.zip: the zip contains 11 files, representing every year from 2011 to 2021. Each file contains the standard protein sequences of virulence factors (from ABVF database) and the associated protein sequences from samples of that year.
Geography
ABVF_Humidity.zip: the zip contains 4 files, representing humid, subhumid, arid and semiarid. Each file contains the standard protein sequences of virulence factors (from ABVF database) and the associated protein sequences from samples of that humidity.
ABVF_Province.zip: the zip contains 25 files and each file represents corresponding province. Each file contains the standard protein sequences of virulence factors (from ABVF database) and the associated protein sequences from samples of that province.
Clinical State Distribution
Infection
ABVF_Infection.zip: the zip contains one file representing infection. This file contains the standard protein sequences of virulence factors (from ABVF database) and the associated protein sequences from samples of infection.
Unknown Pathogenic Factors
To be updated......
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