Christopher D. Green

Former Postdoc
Email: green@picb.ac.cn, cgreen1131@gmail.com

Experience

  • 2009.12 - , Postdoc in Jing-Dong Jackie Han's Lab, IGDB, CAS.

  • 2003.9 - 2009.12, Ph.D. Michigan State University

Research Focus

Identification of key regulatory pathways involved in aging and age-related diseases from an epigenetics perspective.

Publications

  1. Hao Cheng^, Hongwen Xuan^, Christopher D. Green, Yixing Han, Na Sun, Hongjie Shen, Joseph McDermott, David Bennett, Fei Lan and Jing-Dong J. Han*. Repression of human and mouse brain inflammaging transcriptome by broad gene-body histone hyperacetylation. PNAS, Jul 2018.
  2. Na Sun^, Xiaoming Yu^, Fang Li^, Denghui Liu, Shengbao Suo, Weiyang Chen, Shirui Chen, Lu Song, Christopher D. Green, Joseph McDermott, Qin Shen, Naihe Jing and Jing-Dong J. Han*. Inference of differentiation time for single cell transcriptomes using cell population reference data. Nature Communications, Nov 2017.
  3. Christopher D. Green^, Yi Huang^, Xiaoyang Dou^, Liu Yang, Yong Liu and Jing-Dong J. Han*. Impact of Dietary Interventions on Noncoding RNA Networks and mRNAs Encoding Chromatin-Related Factors. Cell Reports, Mar 2017.
  4. Dan Wang^, Lei Hou^, Shuhei Nakamura, Ming Su, Fang Li, Weiyang Chen, Yizhen Yan, Christopher D. Green, Di Chen, Hong Zhang, Adam Antebi and Jing-Dong J. Han*. LIN-28 balances longevity and germline stem cell number in Caenorhabditis elegans through let-7/AKT/DAF-16 axis. Aging Cell, Oct 2016.
  5. Weizhong Chen^, Yi Liu^, Shanshan Zhu, Christopher D. Green, Gang Wei and Jing-Dong J. Han*. Improved nucleosome-positioning algorithm iNPS for accurate nucleosome positioning from sequencing data. Nature Communications, Sep 2014.
  6. Nan Qiao^, Yi Huang^, Hammad Naveed, Christopher D. Green and Jing-Dong J. Han*. CoCiter: An Efficient Tool to Infer Gene Function by Assessing the Significance of Literature Co-Citation. PLoS One, Sep 2013.
  7. Lei Hou, Jialiang Huang, Christopher D. Green, Jerome Boyd-Kirkup, Wei Zhang, Xiaoming Yu, Wenxuan Gong, Bing Zhou and Jing-Dong J. Han*. Systems Biology in Aging: Linking the Old and the Young. Current Genomics, Nov 2012.
  8. Yixing Han^, Dali Han^, Zheng Yan, Jerome D. Boyd-Kirkup, Christopher D. Green, Philipp Khaitovich and Jing-Dong J. Han*. Stress-associated H3K4 methylation accumulates during postnatal development and aging of Rhesus macaque brain. Aging Cell, Sep 2012.
  9. Bing Zhou^, Liu Yang^, Shoufeng Li, Jialiang Huang, Haiyang Chen, Lei Hou, Jinbo Wang, Christopher D. Green, Zhen Yan, Xun Huang, Matt Kaeberlein, Li Zhu, Huasheng Xiao, Yong Liu* and Jing-Dong J. Han*. Midlife gene expressions identify modulators of aging through dietary interventions. PNAS, Apr 2012.
  10. Fang Chen^, Wei Zhang^, Yu Liang^, Jialiang Huang^, Kui Li^, Christopher D. Green^, Jiancheng Liu^, Guojie Zhang, Bing Zhou, Xin Yi, Wei Wang, Hang Liu, Xiaohong Xu, Feng Shen, Ning Qu, Yading Wang, Guoyi Gao, A. San, LuoSang JiangBai, Hua Sang, Xiangdong Fang, Karsten Kristiansen, Huanming Yang, Jun Wang*, Jing-Dong J. Han* and Jian Wang*. Transcriptome and Network Changes in Climbers at Extreme Altitudes. PLoS One, Feb 2012.
  11. Chunyu Jin^, Jing Li^, Christopher D. Green^, Xiaoming Yu, Xia Tang, Dali Han, Bo Xian, Dan Wang, Xinxin Huang, Xiongwen Cao, Zheng Yan, Lei Hou, Jiancheng Liu, Nicholas Shukeir, Philipp Khaitovich, Charlie D. Chen, Hong Zhang, Thomas Jenuwein and Jing-Dong J. Han*. Histone Demethylase UTX-1 Regulates C. elegans Life Span by Targeting the Insulin/IGF-1 Signaling Pathway. Cell Metabolism, Aug 2011.
  12. Christopher D. Green and Jing-Dong J. Han*. Epigenetic regulation by nuclear receptors. Epigenomics, Feb 2011.

  13. Aaron C. Baldwin, Christopher D. Green, L. Karl Olson, Michael A. Moxley and John A. Corbett.     A role for aberrant protein palmitoylation in FFA-induced ER stress and beta cell death. American Journal of Physiology - Endocrinology and Metabolism, Mar 2012.

  14. Christopher D. Green and L. Karl Olson. Modulation of palmitate-induced endoplasmic reticulum stress and apoptosis in pancreatic beta-cells by stearoyl-CoA desaturase and Elovl-6. American Journal of Physiology - Endocrinology and Metabolism, Apr 2011.

  15. Christopher D. Green, Cansel G. Ozguden-Akkoc, Yun Wang, Donald B. Jump and L. Karl Olson. Role of fatty acid elongases in determination of de novo synthesized monounsaturated fatty acid species. Journal of Lipid Research, Jul 2010.

  16. Christopher D. Green, Donald B. Jump and L. Karl Olson.     Elevated insulin secretion from liver X receptor-activated pancreatic beta-cells involves increased de novo lipid synthesis and triacylglyceride turnover. Endocrinology, Jun 2009.

  17. Maria F. Pino, Diana Z. Ye, Katrina D. Linning, Christopher D. Green, Brian Wicksteed, Vincent Poitout and L. Karl Olson.     Elevated glucose attenuates human insulin gene promoter activity in INS-1 pancreatic beta-cells via reduced nuclear factor binding to the A5/core and Z element. Molecular Endocrinology, May 2005.

  18. James P. Luyendyk, Patrick J. Shaw, Christopher D. Green, Jane F. Maddox, Patricia E. Ganey and Robert A. Roth. Coagulation-Mediated Hypoxia and Neutrophil-Dependent Hepatic Injury in Rats Given Lipopolysaccharide and Ranitidine. J Pharmacol Exp Ther, Sep 2005.

  19. James P. Luyendyk, Jane F. Maddox, Christopher D. Green, Patricia E. Ganey, Robert A. Roth. Role of hepatic fibrin in idiosyncrasy-like liver injury from lipopolysaccharide-ranitidine coexposure in rats. Hepatology, Dec 2004.

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