1. Ding, J.*, Li, X.*, Shen, J.*, Zhao, Y., Zhong, S., Lai, L., Niu, H.#, and Qi, Z.# (2023). ssDNA accessibility of Rad51 is regulated by orchestrating multiple RPA dynamics. Nature Communications 14, 3864. 10.1038/s41467-023-39579-y.

  2. Li, Y., Xu, M., and Qi, Z.# (2023). Deciphering molecular mechanisms of phase separation in RNA biology by single-molecule biophysical technologies. Acta Biochimica et Biophysica Sinica 55(7), 1-8.

  3. Zuo, L., Lai, L.#, and Qi, Z.# (2023). Single-Molecule Imaging of the Phase Separation-Modulated DNA Compaction to Study Transcriptional Repression. Methods Mol Biol 2563, 215-223. 10.1007/978-1-0716-2663-4-10.


  1. Wang, H., Li, B., Zuo, L., et al., Qi, Z., Deng, W., and Xiong J. (2022). The transcriptional coactivator RUVBL2 regulates Pol II clustering with diverse transcription factors. Nature Communications 13.

  2. Zhou, R., Tian, K., Huang, J., Duan, W., Fu, H., et al., Qi, Z.#, Ji. X.# (2022). CTCF DNA binding domain undergoes dynamic and selective protein– 2 protein interactions. iScience, 25(9): 105011.

  3. Zuo, L., Ding, J., and Qi, Z. (2022).  Visualizing carboxyl-terminal domain of RNA polymerase II recruitment by FET fusion protein condensates with DNA curtains.  Biophysics Reports 8, 80. 10.52601/bpr.2022.210027. (Invited Review)

  4. Li, L., Wang, J., Yang, Z., Zhao, Y. et al, Qi, Z., Li, Z., Lou, H. (2022). Metabolic remodeling maintains a reducing environment for rapid activation of the yeast DNA replication checkpoint. The EMBO Journal 41, e108290.

  5. Shen, J.*, Zhao, Y.*, Pham, N.T.*, Li, Y., Zhang, Y., Trinidad, J., Ira, G., Qi, Z.#, and Niu, H.# (2022). Deciphering the mechanism of processive ssDNA digestion by the Dna2-RPA ensemble. Nature Communications 13, 359. 10.1038/s41467-021-27940-y.


  1. Zuo, L.*, Ding, J.*, and Qi, Z. (2021). Single-molecule Imaging of EWS-FLI1 Condensates Assembling on DNA. JoVE (Journal of Visualized Experiments), e62974. doi:10.3791/62974 (Invited Review).

  2. Zuo, L., Zhang, G., Massett, M., Cheng, J., Guo, Z., Wang, L., Gao, Y., Li, R., Huang, X.#, Li, P.#, Qi, Z.# (2021). Loci-specific phase separation of FET fusion oncoproteins promotes gene transcription. Nature Communications 12, 1491.

    The editors at Nature Communications have put together an Editors’ Highlights webpage of recent research called “From molecules and cells to organisms” and our paper was chosen to be featured (

    The editors at Nature Communications have put together an Editors’ Highlights webpage of recent research called “Protein Liquid-Liquid Phase Separation in diseases” and our paper was chosen to be featured (


  1. Xu, M.Y., Zhang, C., Zhang, C.J., Zhao, Y.L., Qi, Z., Fan, C.H., Chao, J., and Wei, B. (2020). DNA Origami Nanostructures with Scaffolds Obtained from Rolling Circle Amplification. Acs Mater Lett2, 1322-1327.


  1. Steinfeld, J.B., Belan, O., Kwon, Y., Terakawa, T., Al-Zain, A., Smith, M.J., Crickard, J.B., Qi, Z., Zhao, W.X., Rothstein, R., et al. (2019). Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination. Genes Dev 33, 1191-1207.

  2. Zhou, H., Song, Z., Zhong, S., Zuo, L., Qi, Z.#, Qu, L.-J.#, and Lai, L.# (2019). Mechanism of DNA-Induced Phase Separation for Transcriptional Repressor VRN1. Angewandte Chemie (International ed in English) 58, 4858-4862.

    Our paper has been selected to be featured in PKU Scientific Research Highlights (2019).


  1. Li, S.Q., et al., Qi, Z., and Feng J.X., Li, Q. (2018). Rtt105 functions as a chaperone for Replication Protein A to preserve genome stability. EMBO J. 37(17).


  1. Zhao, Y.L., Jiang, Y.Z., and Qi, Z.# (2017). Visualizing biological reaction intermediates with DNA curtains. Journal of Physics D: Applied Physics 50, 153001-153016 (Invited Review).

  2. Lee, J.Y., Steinfeld, J.B., Qi, Z., Kwon, Y., Sung, P., and Greene, E.C. (2017). Sequence imperfections and base triplet recognition by the Rad51/RecA family of recombinases. J. Biol. Chem., M117. 787614.


  1. Lee, J.Y., Qi, Z., and Greene, E.C. (2016). ATP hydrolysis Promotes Duplex DNA Release by the RecA Presynaptic Complex. J Biol Chem 291, 22218-22230.

  2. Qi, Z., and Greene, E.C. (2016). Visualizing recombination intermediates with single-stranded DNA curtains. Methods 105, 62-74.


  1. Lee, J.Y., Terakawa, T.*, Qi, Z.*, Steinfeld, J.B., Redding, S., Kwon, Y., Gaines, W.A., Zhao, W., Sung, P., and Greene, E.C. (2015). Base triplet stepping by the Rad51/RecA family of recombinases. Science 349, 977-981.

  2. Qi, Z., Redding, S., Lee, J.Y., Gibb, B., Kwon, Y., Niu, H.Y., Gaines, W.A., Sung, P., and Greene, E.C. (2015). DNA Sequence Alignment by Microhomology Sampling during Homologous Recombination. Cell 160, 856-869.