2016 published



Singly Flagellated Pseudomonas aeruginosa Chemotaxes Efficiently by Unbiased Motor Regulation.

Qiuxian Cai,Zhaojun Li,Qi Ouyang,Chunxiong Luo,Vernita D. Gordon.

mBio. 2016;7:e00013-e00013. [Html]

 

Distinct signaling of Drosophila chemoreceptors in olfactory sensory neurons.

Li-Hui Cao,Bi-Yang Jing,Dong Yang,Xiankun Zeng,Ying Shen,Yuhai Tu,Dong-Gen Luo.

Proceedings of the National Academy of Sciences of the United States of America. 2016;113:E902-E911. [Html]

 

Thermodynamics and kinetics of TopoII action: A consensus on T-segment curvature selection? Comment on "Disentangling DNA Molecules" by Alexander Vologodskii.

Chan H S, Liu Z.

Phys Life Rev. 2016;18:135-138. [Html]

 

Designed inhibitor for nuclear localization signal of polo-like kinase 1 induces mitotic arrest.

Chen F, Zhuo X, Qin T, et al.

Chem Biol Drug Des. 2016. [Html]

 

Cab45S promotes cell proliferation through SERCA2b inhibition and Ca2+ signaling.

Chen L, Xu S, Xu Y, et al.

Oncogene. 2016;35:35-46. [Html]

 

Structural basis for dynamic regulation of the human 26S proteasome.

Shuobing Chen,Jiayi Wu,Ying Lu,Yong-Bei Ma,Byung-Hoon Lee,Zhou Yu,Qi Ouyang,Daniel J. Finley,Marc W. Kirschner,Youdong Mao.

Proceedings of the National Academy of Sciences of the United States of America. 2016;113:12991-12996. [Html]

 

Relationship between cancer mutations and parameter sensitivity in Rb pathway.

Chen X, Chen J, Shao B, et al.

J Theor Biol. 2016;404:120-125. [Html]

 

A Flux Balance of Glucose Metabolism Clarifies the Requirements of the Warburg Effect.

Dai Z, Shestov A A, Lai L, et al.

Biophysical Journal. 2016;111:1088-1100. [Html]

 

Indel variant analysis of short-read sequencing data with Scalpel.

Han Fang,Ewa A Bergmann,Kanika Arora,Vladimir Vacic,Michael C Zody,Ivan Iossifov,Jason A O'Rawe,Yiyang Wu,Laura T Jimenez Barron,Julie Rosenbaum,Michael Ronemus,Yoon-ha Lee,Zihua Wang,Esra Dikoglu,Vaidehi Jobanputra,Gholson J Lyon,Michael Wigler,Michael C Schatz,Giuseppe Narzisi.

Nature protocols. 2016;11:2529-2548. [Html]

 

Identifying micro-inversions using high-throughput sequencing reads.

Feifei He,Yang Li,Yu-Hang Tang,Jian Ma,Huaiqiu Zhu.

BMC Genomics. 2016;17 Suppl 1:4. [Html]

 

Conformational Flexibility of a Short Loop near the Active Site of the SARS-3CLpro is Essential to Maintain Catalytic Activity.

Chunmei Li,XinTeng,Yifei Qi,Bo Tang,Hailing Shi,Xiaomin Ma,Luhua Lai.

Sci Rep. 2016;6:20918. [Html]

 

Dimensions, energetics, and denaturant effects of the protein unstructured state.

Maodong Li,Zhirong Liu.

Protein Science. 2016;25:734-747. [Html]

 

Dimension conversion and scaling of disordered protein chains.

Maodong Li,Tanlin Sun,Fan Jin,Daqi Yu,Zhirong Liu.

Molecular Biosystems. 2016;12:2932-2940. [Html]

 

Novel Inhibitors of Toxin HipA Reduce Multidrug Tolerant Persisters.

Tongqing Li,Ning Yin,Hongbo Liu,Jianfeng Pei,Luhua Lai.

Acs Medicinal Chemistry Letters. 2016;7:449-453. [Html]

 

Engineering of core promoter regions enables the construction of constitutive and inducible promoters in Halomonas sp.

Li T T, Li T T, Ji W, et al.

Biotechnology Journal. 2016;11:219-227. [Html]

 

Herb-target interaction network analysis helps to disclose molecular mechanism of traditional Chinese medicine.

Hao Liang,Hao Ruan,Qi Ouyang,Luhua Lai.

Sci Rep. 2016;6:36767. [Html]

 

Similar Fecal Microbiota Signatures in Patients With Diarrhea-Predominant Irritable Bowel Syndrome and Patients With Depression.

Yixuan Liu,Lu Zhang,Xiaoqi Wang,Zhe Wang,Jingjing Zhang,Ronghuan Jiang,Xiangqun Wang,Kun Wang,Zuojing Liu,Zhiwei Xia,Zhijie Xu,Yong Nie,Xianglin Lv,Xiaolei Wu,Huaiqiu Zhu,Liping Duan.

Clin Gastroenterol Hepatol. 2016;14:1602-1611 e1605. [Html]

 

Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism.

Alvin Lu,Yang Li,Florian I Schmidt,Qian Yin,Shuobing Chen,Tian-Min Fu,Alexander B Tong,Hidde L Ploegh,Youdong Mao,Hao Wu.

Nat Struct Mol Biol. 2016;23:416-425. [Html]

 

Motions of Allosteric and Orthosteric Ligand-Binding Sites in Proteins are Highly Correlated.

Xiaomin Ma,Hu Meng,Luhua Lai.

Journal of Chemical Information and Modeling. 2016;56:1725-1733. [Html]

 

A microscopic landscape of the invasive breast cancer genome.

Zheng Ping,Yuchao Xia,Tiansheng Shen,Vishwas Parekh,Gene P. Siegal,IsamEldinEltoum,Jianbo He,Dongquan Chen, Minghua Deng, Ruibin Xi,Dejun Shen.

Sci Rep. 2016;6:27545. [Html]

 

Discovery of Novel Polo-Like Kinase 1 Polo-Box Domain Inhibitors to Induce Mitotic Arrest in Tumor Cells.

Tan Qin,Fangjin Chen,Xiaolong Zhuo,Xiao Guo,Taikangxiang Yun,Ying Liu,Chuanmao Zhang,Luhua Lai.

J Med Chem. 2016;59:7089-7096. [Html]

 

A parallel and quantitative cell migration assay using a novel multi-well-based device.

Quan Q, Zhang S, Wang X, et al.

Biomed Microdevices. 2016;18:99. [Html]

 

The transcriptional repressor Hes1 attenuates inflammation by regulating transcription elongation.

Yingli Shang,Maddalena Coppo,Teng He,Fei Ning,Li Yu,Lan Kang,Bin Zhang,Chanyang Ju,Yu Qiao,Baohong Zhao,Manfred Gessler,Inez Rogatsky,Xiaoyu Hu.

Nat Immunol. 2016;17:930-937. [Html]

 

Long-term dual-color tracking of genomic loci by modified sgRNAs of the CRISPR/Cas9 system.

Shipeng Shao,Weiwei Zhang,Huan Hu,Boxin Xue,Jinshan Qin,Chaoying Sun,Yuao Sun,Wensheng Wei,Yujie Sun.

Nucleic Acids Res. 2016;44:e86. [Html]

 

Study of invasion and colonization of E.

Sun X, Wang S, Yang Y, et al.

faecalis in microtubes by a novel device. Biomed Microdevices. 2016;18:82. [Html]

 

Contributions of Sequence to the Higher-Order Structures of DNA.

Todolli S, Perez P J, Clauvelin N, et al.

Biophys J. 2016. [Html]

 

Graded, Dynamically Routable Information Processing with Synfire-Gated Synfire Chains.

Zhuo Wang,Andrew T. Sornborger,Louis Tao.

PLoS Comput Biol. 2016;12:e1004979. [Html]



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Using Sub-Network Combinations to Scale Up an Enumeration Method for Determining the Network Structures of Biological Functions.

J. Y. Xi,Q. Ouyang.

PLoS One. 2016;11:e0168214. [Html]

 

Adaptation through proportion.

Xiong L, Shi W, Tang C.

Physical biology. 2016;13:46007. [Html]

 

Unsupervised Cryo-EM Data Clustering through Adaptively Constrained K-Means Algorithm.

Yaofang Xu,Jiayi Wu,Chang-Cheng Yin,Youdong Mao.

PLoS One. 2016;11:e0167765. [Html]

 

Structure-based Inhibitor Design for the Intrinsically Disordered Protein c-Myc.

ChenYu,Xiaogang Niu,Fan Jin,Zhirong Liu,Changwen Jin,Luhua Lai.

Sci Rep. 2016;6:22298. [Html]

 

A network based covariance test for detecting multivariate eQTL in saccharomyces cerevisiae.

Huili Yuan,Zhenye Li,Nelson L. S. Tang,Minghua Deng.

BMC Syst Biol. 2016;10 Suppl 1:8. [Html]

 

Discovery of Non-ATP-Competitive Inhibitors of Polo-like Kinase 1.

Taikangxiang Yun,Tan Qin,Ying Liu,Luhua Lai.

ChemMedChem. 2016;11:713-717. [Html]

 

Identification of acylthiourea derivatives as potent Plk1 PBD inhibitors.

Yun T, Qin T, Liu Y, et al.

European Journal of Medicinal Chemistry. 2016;124:229-236. [Html]

 

Improving residue-residue contact prediction via low-rank and sparse decomposition of residue correlation matrix.

Zhang H, Gao Y, Deng M, et al.

Biochem Biophys Res Commun. 2016;472:217-222. [Html]

 

Estimating net primary production of natural grassland and its spatio-temporal distribution in China.

Zhang M, Lal R, Zhao Y, et al.

Science of the Total Environment. 2016;553:184-195. [Html]

 

Gel integration for microfluidic applications.

Xuanqi Zhang,Lingjun Li,Chunxiong Luo.

Lab on a Chip. 2016;16:1757-1776. [Html]

 

Engineering Escherichia coli to bind to cyanobacteria.

Zhang Z, Meng L, Ni C, et al.

J Biosci Bioeng. 2016. [Html]

 

Novel T7-like expression systems used for Halomonas.

Zhao H, Zhang H M, Chen X, et al.

Metab Eng. 2016. [Html]

 

Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2.

Haining Zhou,Tianning Wang,Tao Zheng,Junlin Teng,Jianguo Chen.

Nat Commun. 2016;7:10151. [Html]

 

Rational design of TNFalpha binding proteins based on the de novo designed protein DS119.

Zhu C, Zhang C, Zhang T, et al.

Protein Sci. 2016;25:2066-2075. [Html]

 

Interplay between binding affinity and kinetics in protein-protein interactions.

Huaiqing Cao,Yongqi Huang,Zhirong Liu.

Proteins. 2016;84:920-933. [Html]