Title: Stochastic processes at single-molecule and single-cell levels
Speaker: Dr. Hao Ge
BIOPIC, BICMR, Peking University
Time: 1:00pm Nov 17th 2014
Address: Rm 102, East wing of Old Chemistry Building, Peking Unversity
Chair: Dr. Fangting Li, Center for Quantitative Biology
Abstract:
Due to the advance of single-molecule techniques, stochastic phenomena in chemistry and biology have been widely observed, which promotes the rapid development of stochastic modeling. I will discuss several stochastic processes in single-molecule enzyme kinetics, transcriptional burst and toggle switch. The stochastic modeling not only can explain some unexpected law from the trajectory perspective, but also can help uncover certain molecular mechanism and carefully analyze the effect of noise within gene regulation.