From January 5th to 10th, Professor Chao Tang and lab members Liu Xiang, Xia Kang and Yang Ning attended the Aspen Winter Conference. The theme of the conference was "New physcial model for cell growth". Dozens of scholars discuss the experimental work and theoretical progress of cell growth. Prof. Chao Tang gave a conference report entitled "The role of Whi5 in coordinating growth and division in yeast", which reported in detail the laboratory's research on the cell cycle mechanism of budding yeast in recent years, especially experimental progress and model understanding of Whi5 protein, who played an important role in start transition. Liu Xiang, Xia Kang, and Yang Ning all gave oral reports. Liu Xiang's title was "Bistability of Whi5-SBF-Cln system regulates start". From the perspective of the kinetic model, the bi-stable mechanism of Whi5's Start transition was analyzed. Also the role of concentration dilution caused by growth and the phosphorylation of Cln protein in this process; Xia Kang's title is "Growth Strategy of microbes on mixed carbon sources". Starting from the metabolic network topology, by optimizing protein distribution, a theoretical model is given to quantatively explain the eating strategies of bacteria facing multiple carbon sources; Yang Ning's topic is "Information processing strategy inchanging environment". From the perspective of information theory, he discusses how to make the most appropriate response to the changing environment when the cell is regarded as a signal processing system.
