研究成果 / Research Achievements

Siderophore-mediated iron partition promotes dynamical coexistence between cooperators and cheaters

2023-07-19
立即下载

Authors: Jiqi Shao, Nan Rong, Zhenchao Wu, Shaohua Gu, Beibei Liu, Ning Shen, Zhiyuan Li.

JournaliScience

DOI: 10.1016/j.isci.2023.107396

Link: https://www.cell.com/iscience/fulltext/S2589-0042(23)01473-6

Published: July 19, 2023

Document Type: Article


Highlights:

  • Siderophore-mediated iron partition allows for the cooperator–cheater coexistence

  • The resource partition mechanism bypasses competitive exclusion

  • Chemical innovation leads to different stability criteria than classical models


Summary:

Microbes shape their habitats by consuming resources and producing a diverse array of chemicals that can serve as public goods. Despite the risk of exploitation by cheaters, genes encoding sharable molecules like siderophores are widely found in nature, prompting investigations into the mechanisms that allow producers to resist invasion by cheaters. In this work, we presented the chemostat-typed “resource partition model” to demonstrate that dividing the iron resource between private and public siderophores can promote stable or dynamic coexistence between producers and cheaters in a well-mixed environment. Moreover, our analysis shows that when microbes not only consume but also produce resources, chemical innovation leads to stability criteria that differ from those of classical consumer resource models, resulting in more complex dynamics. Our work sheds light on the role of chemical innovations in microbial communities and the potential for resource partition to facilitate dynamical coexistence between cooperative and cheating organisms.

在线交流 x