Bo Xian

Former Associate Researcher
Email: bioxian@163.com

Experience

  • 2011.6 - 2018.12, Han Lab, PICB, SIBS, CAS.

  • 2005.12 - 2011.6, Han Lab, Institute of Genetics and Developmental Biology, CAS.

  • 2004.9 - 2005.11, Hu Lab, Institute of Genetics and Developmental Biology, CAS.

  • 2003.9 - 2004.8, 2003508, Graduate University of CAS.

  • 1999.9 - 2003.7, Beijing Forestry University.

Research Focus

My research interests are to systematically investigate the aging process and screen anti-aging natural compounds by applying automatic microfluidic technology on C.elegans.

Publications

  1. Xian Xia^, Xingwei Chen^, Gang Wu, Fang Li, Yiyang Wang, Yang Chen, Mingxu Chen, Xinyu Wang, Weiyang Chen, Bo Xian, Weizhong Chen, Yaqiang Cao, Chi Xu, Wenxuan Gong, Guoyu Chen, Donghong Cai, Wenxin Wei, Yizhen Yan, Kangping Liu, Nan Qiao, Xiaohui Zhao, Jin Jia, Wei Wang, Brian K. Kennedy, Kang Zhang, Carlo V. Cannistraci, Yong Zhou* and Jing-Dong J. Han*. Three-dimensional facial-image analysis to predict heterogeneity of the human ageing rate and the impact of lifestyle. Nature Metabolism, Sep 2020.
  2. Lei Hou, Dan Wang, Hao Cheng, Bo Xian and Jing-Dong J Han. Handbook of the Biology of Aging (Eighth Edition) by Academic Press, Chapter 8: Systems Approaches to Understanding Aging. Oct 2015.
  3. Weiyang Chen, Wei Qian, Gang Wu, Weizhong Chen, Bo Xian, Xingwei Chen, Yaqiang Cao, Christopher D Green, Fanghong Zhao, Kun Tang and Jing-Dong J. Han*. Three-dimensional human facial morphologies as robust aging markers. Cell Research, Mar 2015.
  4. Bo Xian^, Jie Shen^, Weiyang Chen^, Na Sun, Nan Qiao, Dongqing Jiang, Tao Yu, Yongfan Men, Zhijun Han, Yuhong Pang, Matt Kaeberlein, Yanyi Huang and Jing-Dong J. Han*. WormFarm: a quantitative control and measurement device toward automated Caenorhabditis elegans aging analysis. Aging Cell, Feb 2013.
  5. Chunyu Jin^, Jing Li^, Christopher D. Green^, Xiaoming Yu, Xia Tang, Dali Han, Bo Xian, Dan Wang, Xinxin Huang, Xiongwen Cao, Zheng Yan, Lei Hou, Jiancheng Liu, Nicholas Shukeir, Philipp Khaitovich, Charlie D. Chen, Hong Zhang, Thomas Jenuwein and Jing-Dong J. Han*. Histone Demethylase UTX-1 Regulates C. elegans Life Span by Targeting the Insulin/IGF-1 Signaling Pathway. Cell Metabolism, Aug 2011.
  6. Jing-Dong J. Han*, Yi Liu^, Huiling Xue^, Kai Xia^, Hong Yu^, Shanshan Zhu^, Zhang Chen, Wei Zhang, Chunyu Jin, Bo Xian, Jing Li, Lei Hou, Yixing Han, Chaoqun Niu and Timothy C. Alcon. Developmental systems biology flourishing on new technologies. Journal of Genetics and Genomics, Oct 2008.
  7. Huiling Xue^, Bo Xian^, Dong Dong, Kai Xia, Shanshan Zhu, Zhongnan Zhang, Lei Hou, Qingpeng Zhang, Yi Zhang and Jing-Dong J. Han*. A modular network model of aging. Molecular Systems Biology, Dec 2007.

  8. Shan Gao^, Weiyang Chen^, Yingxin Zeng, Haiming Jing, Nan Zhang, Matthew Flavel, Markandeya Jois, Jing-Dong J Han, Bo Xian* and Guojun Li*. Classification and prediction of toxicity of chemicals using an automated phenotypic profiling of Caenorhabditis elegans. BMC Pharmacology and Toxicology, Apr 2018.

  9. Weiyang Chen*, Bo Liao, Weiwei Li, Xiangjun Dong*, Matthew Flavel, Markandeya Jois, Guojun Li and Bo Xian. Segmenting Microscopy Images of Multi-Well Plates Based on Image Contrast. Microscopy and Microanalysis, Oct 2017.

  10. Matthew R Flavel, Adam Mechler, Mahdi Shahmiri, Elizabeth R Mathews, Ashley E Franks, Weisan Chen, Damien Zanker, Bo Xian, Shan Gao, Jing Luo, Surafel Tegegne, Christian Doneski and Markandeya Jois*. Growth of Caenorhabditis elegans in Defined Media Is Dependent on Presence of Particulate Matter. G3 (Bethesda), Dec 2017.

  11. Jennifer Schleit, Simon C Johnson, Christopher F Bennett, Marissa Simko, Natalie Trongtham, Anthony Castanza, Edward J Hsieh, Richard M Moller, Brian M Wasko, Joe R Delaney, George L Sutphin, Daniel Carr, Christopher J Murakami, Autumn Tocchi, Bo Xian and et al. Aging Cell, Jul 2013.

  12. Han Zhang, Yun-wu Zhang, Yaomin Chen, Xiumei Huang, Fangfang Zhou, Weiwei Wang, Bo Xian, Xian Zhang, Eliezer Masliah, Quan Chen, Jing-Dong J Han, Guojun Bu, John C Reed, Francesca-Fang Liao, Ye-Guang Chen and Huaxi Xu. Appoptosin is a novel pro-apoptotic protein and mediates cell death in neurodegeneration. The Journal of Neuroscience, Oct 2012.

Personal Show

  • Hobbies: Photograhy, Pool, Fishing...