Tools
Repositories
Cancer Immunolgoy
- ICRAFT Immune-related CRispr screen Analyzer of Functional Targets (ICRAFT) has an extensive collection of genome-scale CRISPR screens focusing on gene's immune-modulatory effects. ICRAFT provides interactive web interfaces for users to investigate whether specific gene perturbation influences immune-modulatory functions.
- TISMO Tumor Immune Syngeneic MOuse (TISMO) is a database specifically designed for hosting, visualizing, and analyzing immunotherapy response and immune infiltration of an extensive collection of syngeneic mouse model data.
Spatial Transcriptomics
- SPATCH SPAtial Transcriptomics resource for subCellular and High-throughput platforms (SPATCH) is a spatial transcriptomics database providing convenient tools for data visualization and exploration for 5 high-throughput spatial transcriptomics platforms with subcellular resolution and also the paired CODEX and scRNA-seq data.
- STAGE The Spatial TrAnscriptomics and multi-omics of female GEnital tumors (STAGE) comprises a comprehensive dataset from 546 ovarian, endometrial, and cervical cancer samples, including whole-exome sequencing, RNA sequencing, whole-genome methylation sequencing, microRNA sequencing, and Visium HD spatial transcriptome sequencing, along with detailed clinical information for the samples.
- DISSECT (DIffusion-based cell Segmentation integrating Spatially rEsolved transCripTome) is an advanced cell segmentation algorithm developed by the Zeng Lab. It combines cytological image segmentation with transcriptome-guided fine-tuning to achieve precise spatial transcriptome reconstruction.
- TARDIS (TArget pRioritization toolkit for CRISPR Data In Spatial-omics) is a comprehensive toolkit for spatial CRISPR screening analysis.
- SOAR Spatial transcriptOmics Analysis Resource (SOAR) is a comprehensive database of 132 spatial transcriptomics datasets from six species across 22 tissue types.