担任职务：

北京大学定量生物学中心副研究员。

研究方向：

计算合成生物学

DNA 分子信息存储

单分子测序、基因组学

工作经历：

2014-2018；美国纽约大学博士后研究员

代表性文章：

Wang T, Qin R BW, Li S, Wang Z, Li X, et al. Discovery of Diverse and High-quality mRNA Capping Enzymes through a Language Model-enabled Platform. Science Advances 11(15):eadt0402 (2025).

Zhang C, Wu R, Sun F, Lin Y, Liang Y, et al. Parallel Molecular Data Storage by Printing Epigenetic Bits on DNA. Nature 638:824-832 (2024).

Sun F, Dong Y, Ni M, Ping Z, Sun Y, et al. Mobile and self-sustained data storage in an extremophile genomic DNA. Advanced Science 10(10): 2206201 (2023).

Qin C, Xiang Y, Liu J, Zhang R, Liu Z, et al. Precise programming of multigene expression stoichiometry in mammalian cells by a modular and programmable transcriptional system. Nature Communications 14: 1500 (2023).

Yang J, Liang Y, Li X, Qian L, Ke Y, Zhang C. Spatially programmable enzymatic nanorobot arm to modulate anisotropic gold nanoparticle assembly. Angew. Chem. Int. Ed. 62(43): e202308797 (2023).

Dong Y, Sun F, Ping Z, Ouyang Q, Qian L. DNA storage: research landscape and future prospects. National Science Review 7: 1092-1107 (2020).

Du P, Zhao H, Zhang H, Wang R, Huang J, et al. De novo design of an intercellular signaling toolbox for multi-channel cell–cell communication and biological computation. Nature Communications 11(1): 4226 (2020).

Zhang Y, Qian L, Wei W, Wang Y, Wang B, et al. Paired design of dCas9 as a systematic platform for the detection of featured nucleic acid sequences in pathogenic strains. ACS Synthetic Biology 6(2):211-216 (2017).

Pleska M, Qian L, Okura R, Bergmiller T, Wakamoto Y, Kussell E, and Guet CC. Bacterial autoimmunity due to a restriction-modification system. Current Biology 26(3): 404-409 (2016). 

Qian L and Kussell E. Genome-wide motif statistics are shaped by DNA binding proteins over evolutionary time scales. Physical Review X 6, 041009 (2016). 

Qian L and Kussell E. Evolutionary dynamics of restriction site avoidance. Physical Review Letters 108: 158105 (2012).