担任职务：

北京大学定量生物学中心副研究员。

研究方向：

计算合成生物学

DNA 分子信息存储

单分子测序、基因组学

工作经历：

2014-2018；美国纽约大学博士后研究员

代表性文章：

Wang T, Qin R BW, Li S, Wang Z, Li X, et al. Discovery of Diverse and High-quality mRNA Capping Enzymes through a Language Model-enabled Platform. Science Advances in press (2025).

Zhang C, Wu R, Sun F, Lin Y, Liang Y, et al. Parallel Molecular Data Storage by Printing Epigenetic Bits on DNA. Nature 638:824-832 (2024).

Sun F, Dong Y, Ni M, Ping Z, Sun Y, et al. Mobile and self-sustained data storage in an extremophile genomic DNA. Advanced Science 10(10): 2206201 (2023).

Qin C, Xiang Y, Liu J, Zhang R, Liu Z, et al. Precise programming of multigene expression stoichiometry in mammalian cells by a modular and programmable transcriptional system. Nature Communications 14: 1500 (2023).

Yang J, Liang Y, Li X, Qian L, Ke Y, Zhang C. Spatially programmable enzymatic nanorobot arm to modulate anisotropic gold nanoparticle assembly. Angew. Chem. Int. Ed. 62(43): e202308797 (2023).

Dong Y, Sun F, Ping Z, Ouyang Q, Qian L. DNA storage: research landscape and future prospects. National Science Review 7: 1092-1107 (2020).

Du P, Zhao H, Zhang H, Wang R, Huang J, et al. De novo design of an intercellular signaling toolbox for multi-channel cell–cell communication and biological computation. Nature Communications 11(1): 4226 (2020).

Zhang Y, Qian L, Wei W, Wang Y, Wang B, et al. Paired design of dCas9 as a systematic platform for the detection of featured nucleic acid sequences in pathogenic strains. ACS Synthetic Biology 6(2):211-216 (2017).

Pleska M, Qian L, Okura R, Bergmiller T, Wakamoto Y, Kussell E, and Guet CC. Bacterial autoimmunity due to a restriction-modification system. Current Biology 26(3): 404-409 (2016). 

Qian L and Kussell E. Genome-wide motif statistics are shaped by DNA binding proteins over evolutionary time scales. Physical Review X 6, 041009 (2016). 

Qian L and Kussell E. Evolutionary dynamics of restriction site avoidance. Physical Review Letters 108: 158105 (2012).