CSRC Workshop

Dr. Chen Song was invited to give a talk at the “Workshop on the Methods of Protein Structure and Dynamics”, at Beijing Computational Science Research Center on 12-13 Dec, 2018. The whole group attended the session of computational methods.

Prof. Ran Friedman visited us

Prof. Ran Friedman (Linnaeus University, Sweden) visited us and delivered a seminar entitled “Computer simulation in cancer research … and whisky” on 8 Nov 2018.

Prof. Catherine C.L. Wong visited us

Invited by Dr. Chen SONG, Prof. Catherine C.L. WONG (Director of the Center for Precision Medicine Multiomics, PKUHSC) visited us and gave a wonderful talk entitled “Mass Spectrometry-based Omics Technologies in Life Science: Basic Research and Applications”.

The OSCA Paper Online

Based on Lei CHEN Lab’s cryo-EM structure of OSCA, we explored the possible ion permeation pathway of this mechanosensitive ion channel and simulated its conformational changes in response to membrane surface tension. The results match with mutagenesis and electrophysiology studies, and a mechano-gating mechanism was proposed. It’s been a very smooth and successful collaboration between three labs: Lei CHEN’s lab@PKU, Zhiqiang YAN’s lab@Fudan, and us.

Dali Wang performed the computational work. The paper has appeared online: https://www.nature.com/articles/s41594-018-0117-6

Prof. Ulrich Zachariae visited us

Prof. Ulrich Zachariae from the University of Dundee visited us 26 Aug – 2 Sep. He gave us a brilliant seminar, and had lots of interesting discussions with faculties and students at CQB.

Two NSFC Grants Approved

We won two research grants from the National Natural Science Foundation of China (NSFC): one to Dr. Chen Song and one to Dr. Yanyan Liu. Thanks to all the group members who have been involved in the research and grant application.